CN106389865A - Taxillus-caloreas medicinal cake for treating cervical vertebral hyperosteogeny - Google Patents

Taxillus-caloreas medicinal cake for treating cervical vertebral hyperosteogeny Download PDF

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Publication number
CN106389865A
CN106389865A CN201611104999.XA CN201611104999A CN106389865A CN 106389865 A CN106389865 A CN 106389865A CN 201611104999 A CN201611104999 A CN 201611104999A CN 106389865 A CN106389865 A CN 106389865A
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hyperosteogeny
cervical vertebra
active component
prepared
caloreas
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张俊宝
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

The invention relates to a taxillus-caloreas medicinal cake for treating cervical vertebral hyperosteogeny. The traditional Chinese medicine is prepared from, by weight, taxillus caloreas, pholidota chinensis, flos rhododendri mollis, rhodomyrtus tomentosa hassk, erythrina indica lam, radix angelicae pubescentis, angelica sinensis, roots and stems of kadsura, common yam rhizomes, white atractylodes rhizomes, nduoh nyaatv buerng, roots and stems of sabia discolor dunn and white paeony roots. According to the traditional Chinese medicine composition, in the aspect of treating various kinds of cervical vertebral hyperosteogeny caused by cold-dampness closing of meridians and collaterals, the curative effect is exact, safety is good, side effects are avoided, using is convenient, the cost is low, and the effect is better than that of the prior art.

Description

A kind of Taxillus caloreas (Diels) Danser medicine cake treating hyperosteogeny of cervical vertebra
Technical field
The present invention relates to the field of Chinese medicines is and in particular to a kind of Taxillus caloreas (Diels) Danser medicine cake treating hyperosteogeny of cervical vertebra.
Background technology
Hyperosteogeny is to lead to local joint, muscle, ligament moving obstacle with sclerotin pathological proliferation, based on the pain that occurs together Want the disease of symptom.Can occur in cervical vertebra, cervical vertebra, joint and calcaneus etc., including hypertrophy spondylitiss, hpertrophic osteoarthropathy And calcanean spur etc..Primary disease is apt to occur in the person in middle and old age of more than 40 years old and is engaged in load-bearing, long station, the staff of sitting, with activity The larger joint of scope, vertebra pathological changes common.The cause of disease of bone matrix hyperplasia is unknown so far, belongs to senile degenerative disease more The category becoming, a lot of with regard to its etiology and pathogenesis hypothesis, such as machinery is said, function is said, angiopathy, dysbolism, endocrine Obstacle etc..Basic understandings are on the basis of endogenous cause of ill, are led to by the induction of exopathogenic factor fall ill.Doctor trained in Western medicine adopts non-hormone antiinflammatory at present Analgesic drug product, physical therapy and operative treatment, have certain effect to relief of symptoms, but there is no special effective therapy so far.
Fomentation method be using medicine and suitable adjuvant after heat treated, spread on one kind side for the treatment of of affected part or acupuncture points on the human body Method.This law is that the traditional Chinese medical science is unique, one of effective external treatment.It can by the power of warm, by the property of medicine by expressing in, by the fur natural fibre line of meat Reason, follows through running, inside reaching internal organs, dredging the meridian, warming spleen and stomach for dispelling cold, unimpeded mechanism of qi, analgesia detumescence, adjusting internal organs negative and positive, thus reaching To the purpose cured the disease.This law is simple to operate, draws materials conveniently, and indication is wide, Small side effects, low cost, and safe no pain, is value The outer treating method that must promote.
Content of the invention
It is an object of the invention to provide a kind of Taxillus caloreas (Diels) Danser medicine cake treating hyperosteogeny of cervical vertebra.
The purpose of the present invention is to be realized by following technical scheme：
The medicine cake for the treatment of hyperosteogeny of cervical vertebra of the present invention, is to be prepared from by the raw material of Chinese medicine of following weight portion：
Taxillus caloreas (Diels) Danser 10-30 part, Radix Phytolaccae 5-20 part, hair tiger 5-20 part, Fructus Rhodomyrti 10-30 part, Cortex erythrinae 10-30 part, Radix Angelicae Pubescentiss 10-30 part, Radix Angelicae Sinensis 5-20 part, white brill 10-30 part, Rhizoma Dioscoreae 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Herba Pileae Scriptae 3-10 part, scattered greatly GUFENG 10-30 part, Radix Paeoniae Alba 3-10 part.
Preferably, it is to be prepared from by the raw material of Chinese medicine of following weight portion：
Taxillus caloreas (Diels) Danser 15-25 part, Radix Phytolaccae 8-15 part, hair tiger 8-15 part, Fructus Rhodomyrti 15-25 part, Cortex erythrinae 15-25 part, Radix Angelicae Pubescentiss 15-25 part, Radix Angelicae Sinensis 8-15 part, white brill 15-25 part, Rhizoma Dioscoreae 8-15 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Herba Pileae Scriptae 5-8 part, scattered greatly GUFENG 15- 25 parts, Radix Paeoniae Alba 5-8 part.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and the method is Ethanol extraction using water extraction or 40-80% concentration expressed in percentage by volume is prepared from.Concrete preparation method is as follows：
Scheme one：Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to 6-12 times of medical material gross weight, Extraction time is 1-3 hour every time, united extraction liquid, filtration, and it is 1.15-1.20 that filtrate is concentrated into relative density when 70-80 DEG C Clear paste, obtain final product active component.
Scheme two：Take whole medical materials, after mixing, use 40-80% alcohol reflux 2-3 time, each ethanol consumption is medical material total amount 4-10 times, extraction time is 1-4 hour, and united extraction liquid filters, filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, obtains final product active component.
Scheme three：Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6- of medical material gross weight 12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, adds ethanol, makes alcohol content be 40-70%, stands 12-24 hour, filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 extractum, obtain final product active component.
The medicine cake for the treatment of hyperosteogeny of cervical vertebra of the present invention, is prepared by the following method and forms：Take whole medicines Material, micronizing, cross 300-400 mesh sieve, mix homogeneously, add the flour of 1-2 times of medical material weight, the rubbing that adds water is extremely agglomerating not Dissipate, obtain final product.
The medicine cake for the treatment of hyperosteogeny of cervical vertebra of the present invention, is prepared by the following method and forms：Take scheme one One of to scheme three gained active component, add the flour of 1-2 times of medical material weight, the rubbing that adds water does not dissipate to agglomerating, puts into mould Machine-shaping, obtains final product.
During use, dough is heated to 40-50 DEG C, fomentation affected part, you can.
Inventive formulation is rationally innovated, Taxillus caloreas (Diels) Danser, Radix Phytolaccae, Radix Paeoniae Alba expelling wind and activating blood circulation in side, heat-clearing and toxic substances removing, reducing swelling and alleviating pain； Hair tiger expelling wind and removing dampness, promoting blood circulation and stopping pain；Fructus Rhodomyrti nourishing YIN and benefiting blood；Cortex erythrinae heat-clearing and toxic substances removing；Radix Angelicae Pubescentiss, Radix Angelicae Sinensis, white brill, Rhizoma Dioscoreae wind-dispelling Active, pain relieving bone strengthening；Rhizoma Atractylodis Macrocephalae promoting blood circulation to remove blood stasis, expelling wind and removing dampness, reunion of fractured tendons and bones；Herba Pileae Scriptae, scattered greatly GUFENG blood circulation promoting and blood stasis dispelling, dehumidifying disappears Swollen.Side plays expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling altogether entirely, and the work(of reducing swelling and alleviating pain, for treating hyperosteogeny of cervical vertebra.
A kind of Taxillus caloreas (Diels) Danser medicine cake treating hyperosteogeny of cervical vertebra that the present invention provides has advantages below：
1st, the compositionss that the present invention provides safely and effectively, have expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the work(of reducing swelling and alleviating pain, for treating Hyperosteogeny of cervical vertebra.
2nd, the total effective rate of the composition treatment hyperosteogeny of cervical vertebra that the present invention provides is 92.9%, and treatment cervical vertebra increases Life is evident in efficacy.
3rd, Traditional Chinese medicine composition formula of the present invention is rationally innovated, low production cost, process is simple.
Specific embodiment
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for illustrating The present invention rather than limitation of the present invention.Broadly fall into the present invention according to the simple modifications that the essence of the present invention is carried out to the present invention Claimed scope.Unless otherwise stated, the percent of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution Volume ratio.
Embodiment 1
Weigh Taxillus caloreas (Diels) Danser 1kg, Radix Phytolaccae 0.5kg, hair tiger 0.5kg, Fructus Rhodomyrti 1kg, Cortex erythrinae 1kg, Radix Angelicae Pubescentiss 1kg, Radix Angelicae Sinensis 0.5kg, in vain brill 1kg, Rhizoma Dioscoreae 0.5kg, Rhizoma Atractylodis Macrocephalae 1kg, Herba Pileae Scriptae 0.3kg, scattered greatly GUFENG 1kg, Radix Paeoniae Alba 0.3kg.Extracting in water 3 Secondary, three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, three extraction times be respectively 3 hours, 2 hours, 1 little When, united extraction liquid, filtration, when filtrate is concentrated into 70 DEG C, relative density is 1.25 clear paste, adds the face of 1 times of medical material weight Powder, the rubbing that adds water does not dissipate to agglomerating, obtains final product.
Embodiment 2
Weigh Taxillus caloreas (Diels) Danser 3kg, Radix Phytolaccae 2kg, hair tiger 2kg, Fructus Rhodomyrti 3kg, Cortex erythrinae 3kg, Radix Angelicae Pubescentiss 3kg, Radix Angelicae Sinensis 2kg, white Bore 3kg, Rhizoma Dioscoreae 2kg, Rhizoma Atractylodis Macrocephalae 3kg, Herba Pileae Scriptae 1kg, dissipate greatly GUFENG 3kg, Radix Paeoniae Alba 1kg.With 40% alcohol reflux 3 times, every time Ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours, 2 hours, 1 hour respectively extraction time, united extraction Liquid, filters, and when filtrate concentrates 60 DEG C, relative density is 1.25 extractum, adds the flour of 2 times of medical material weight, and the rubbing that adds water extremely becomes Group does not dissipate, and obtains final product.
Embodiment 3
Weigh Taxillus caloreas (Diels) Danser 1.5kg, Radix Phytolaccae 0.8kg, hair tiger 0.8kg, Fructus Rhodomyrti 1.5kg, Cortex erythrinae 1.5kg, Radix Angelicae Pubescentiss 1.5kg, Radix Angelicae Sinensis 0.8kg, in vain brill 1.5kg, Rhizoma Dioscoreae 0.8kg, Rhizoma Atractylodis Macrocephalae 1.5kg, Herba Pileae Scriptae 0.5kg, scattered greatly GUFENG 1.5kg, the Radix Paeoniae Alba 0.5kg.Extracting in water 3 times, three times amount of water is respectively equivalent to 12 times of medical material gross weight, 8 times, 6 times, and each extraction time divides Other 3 hours, 2 hours, 1 hour, united extraction liquid, filtration, when filtrate is concentrated into 70 DEG C, relative density is 1.20 clear paste, adds Ethanol, makes alcohol content be 40%, stands 24 hours, filtration, and it is 1.10 that filtrate is concentrated into relative density when filtrate is concentrated into 70 DEG C Extractum, adds the flour of 2 times of medical material weight, and the rubbing that adds water does not dissipate to agglomerating, obtains final product.
Embodiment 4
Weigh Taxillus caloreas (Diels) Danser 2.5kg, Radix Phytolaccae 1.5kg, hair tiger 1.5kg, Fructus Rhodomyrti 2.5kg, Cortex erythrinae 2.5kg, Radix Angelicae Pubescentiss 2.5kg, Radix Angelicae Sinensis 1.5kg, in vain brill 2.5kg, Rhizoma Dioscoreae 1.5kg, Rhizoma Atractylodis Macrocephalae 2.5kg, Herba Pileae Scriptae 0.8kg, scattered greatly GUFENG 2.5kg, the Radix Paeoniae Alba 0.8kg.With alcohol reflux 2 times, each concentration of alcohol is respectively 80%, 60%, and each ethanol consumption is respectively medical material total amount 10 times, 8 times, extraction time be respectively 4 hours, 3 hours, united extraction liquid, filter, relative density when filtrate is concentrated into 80 DEG C Extractum for 1.10, adds the flour of 1.5 times of medical material weight, and the rubbing that adds water does not dissipate to agglomerating, obtains final product.
Embodiment 5
Weigh Taxillus caloreas (Diels) Danser 2kg, Radix Phytolaccae 1kg, hair tiger 1kg, Fructus Rhodomyrti 2kg, Cortex erythrinae 2kg, Radix Angelicae Pubescentiss 2kg, Radix Angelicae Sinensis 1kg, white Bore 2kg, Rhizoma Dioscoreae 1kg, Rhizoma Atractylodis Macrocephalae 2kg, Herba Pileae Scriptae 0.7kg, dissipate greatly GUFENG 2kg, Radix Paeoniae Alba 0.7kg.Take whole medical materials, micronizing, Cross 300 mesh sieves, mix homogeneously, add the flour of 1 times of medical material weight, the rubbing that adds water does not dissipate to agglomerating, obtains final product.
Embodiment 6
Weigh Taxillus caloreas (Diels) Danser 2.3kg, Radix Phytolaccae 1.2kg, hair tiger 0.8kg, Fructus Rhodomyrti 1.8kg, Cortex erythrinae 2.3kg, Radix Angelicae Pubescentiss 1.8kg, Radix Angelicae Sinensis 0.6kg, in vain brill 1.2kg, Rhizoma Dioscoreae 1.5kg, Rhizoma Atractylodis Macrocephalae 2kg, Herba Pileae Scriptae 0.6kg, scattered greatly GUFENG 2.3kg, the Radix Paeoniae Alba 0.4kg.Take whole medical materials, micronizing, cross 400 mesh sieves, mix homogeneously, add the flour of 2 times of medical material weight, add water rubbing extremely Agglomerating do not dissipate, obtain final product.
Clinical trial is summarized
1 basic document
Observe hyperosteogeny of cervical vertebra patient 42, man 18, female 24, age 28-70 year, the course of disease exclusion gestation and age of sucking Women, those who are allergic to this drug, late deformity, maimed person, disability person.Patient all haves a medical check-up through x-ray and is diagnosed as cervical vertebra increasing Raw.
2 Therapeutic Method
With the dough of the embodiment of the present invention 5, during use, dough is heated to 40-50 DEG C, fomentation affected part, repeated multiple times, it is within 1 week 1 The individual course for the treatment of, after observation and treatment, symptom changes situation, administration time 2 weeks -2 months.
3 curative effect judging standards
Recovery from illness：Clinical symptom disappearance, freely, x line check bone matrix hyperplasia does not have growth to local movement, and after 1 year, follow-up is no multiple Send out.
Effective：Clinical symptoms disappear substantially, and local movement is no substantially limited.
Effectively：Clinical symptoms are obviously improved, tired or may occur in which symptom after catching cold, but have mitigated earlier above, may participate in relatively Light work.
Invalid：2～3 courses for the treatment of are treated in medication, and clinical symptoms improvement is inconspicuous, and joint movement disorder is unchanged, very then adds Weight.5 the results are shown in Table 1.
Table 1 efficacy result
Recovery from illness Effective Effectively Invalid Effective percentage（%）
Curative effect 6 15 18 3 92.9
Clinical effectiveness shows：The medicine disease that the present invention treats hyperosteogeny of cervical vertebra to the total effective rate of hyperosteogeny of cervical vertebra patient is 92.9%, result shows, the present invention has the curative effect of good treatment hyperosteogeny of cervical vertebra.
Model case：
Case 1：What XX, female, 46 years old.Often feel dizzy, numbness of hand, make a definite diagnosis hyperosteogeny of cervical vertebra 3 through hospital and save, give the present invention Embodiment 3 is treated, and treats March, dizzy, and numbness of hand symptom disappears, and continues to strengthen treatment January, and further consultation after 1 year cannot be sent out, and follow-up is extremely Modern preferable.
Although, above used general explanation, specific embodiment and test, the present invention made retouch in detail State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art 's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed Scope.

Claims (6)

1. a kind of Taxillus caloreas (Diels) Danser medicine cake treating hyperosteogeny of cervical vertebra is it is characterised in that it is by the raw material of Chinese medicine of following weight portion It is prepared from：Taxillus caloreas (Diels) Danser 10-30 part, Radix Phytolaccae 5-20 part, hair tiger 5-20 part, Fructus Rhodomyrti 10-30 part, Cortex erythrinae 10-30 Part, Radix Angelicae Pubescentiss 10-30 part, Radix Angelicae Sinensis 5-20 part, white bore 10-30 part, Rhizoma Dioscoreae 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Herba Pileae Scriptae 3-10 part, big Scattered GUFENG 10-30 part, Radix Paeoniae Alba 3-10 part.
2. the medicine cake for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 1 is it is characterised in that it is by the following weight portion of inclusion Raw material of Chinese medicine be prepared from：Taxillus caloreas (Diels) Danser 15-25 part, Radix Phytolaccae 8-15 part, hair tiger 8-15 part, Fructus Rhodomyrti 15-25 part, sea Cortex paulowniae 15-25 part, Radix Angelicae Pubescentiss 15-25 part, Radix Angelicae Sinensis 8-15 part, white brill 15-25 part, Rhizoma Dioscoreae 8-15 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Herba Pileae Scriptae 5-8 part, scattered greatly GUFENG 15-25 part, Radix Paeoniae Alba 5-8 part.
3. the medicine cake for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 1 or 2 is it is characterised in that its active component is to adopt It is prepared from the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume.
4. as claimed in claim 3 treatment hyperosteogeny of cervical vertebra medicine cake it is characterised in that its active component be by with Lower section method is prepared from：Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to medical material gross weight 6-12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, obtains final product active component.
5. as claimed in claim 3 treatment hyperosteogeny of cervical vertebra medicine cake it is characterised in that its active component be by with Lower section method is prepared from：Take whole medical materials, after mixing, use 40-80% alcohol reflux 2-3 time, each ethanol consumption is medicine 4-10 times of material total amount, extraction time is 1-4 hour, and united extraction liquid filters, and filtrate is concentrated into relative density when 70-80 DEG C Clear paste for 1.15-1.20, obtains final product active component.
6. as claimed in claim 3 treatment hyperosteogeny of cervical vertebra medicine cake it is characterised in that its active component be by with Lower section method is prepared from：Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to medical material gross weight 6-12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, adds ethanol, makes alcohol content be 40-70%, stands 12-24 hour, filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 extractum, obtain final product active component.
CN201611104999.XA 2016-12-05 2016-12-05 Taxillus-caloreas medicinal cake for treating cervical vertebral hyperosteogeny Pending CN106389865A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362491A (en) * 2015-11-25 2016-03-02 张立 External-use medicine for treating cervical vertebra hyperosteogeny
CN105362439A (en) * 2015-11-25 2016-03-02 张立 External medicine for treating lumbar vertebrae hyperosteogeny

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362491A (en) * 2015-11-25 2016-03-02 张立 External-use medicine for treating cervical vertebra hyperosteogeny
CN105362439A (en) * 2015-11-25 2016-03-02 张立 External medicine for treating lumbar vertebrae hyperosteogeny

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