CN106388872A - Living tissue puncturing and sampling needle - Google Patents

Living tissue puncturing and sampling needle Download PDF

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Publication number
CN106388872A
CN106388872A CN201610869544.0A CN201610869544A CN106388872A CN 106388872 A CN106388872 A CN 106388872A CN 201610869544 A CN201610869544 A CN 201610869544A CN 106388872 A CN106388872 A CN 106388872A
Authority
CN
China
Prior art keywords
cutter
hollow
negative pressure
sickle
tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610869544.0A
Other languages
Chinese (zh)
Inventor
叶雨
张剑锋
谢招娣
余永当
刘云
王茹月
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
First Affiliated Hospital of Guangxi Medical University
Original Assignee
First Affiliated Hospital of Guangxi Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of Guangxi Medical University filed Critical First Affiliated Hospital of Guangxi Medical University
Priority to CN201610869544.0A priority Critical patent/CN106388872A/en
Publication of CN106388872A publication Critical patent/CN106388872A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • A61B10/0275Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0225Instruments for taking cell samples or for biopsy for taking multiple samples

Abstract

The invention discloses a living tissue puncturing and sampling needle. The living tissue puncturing and sampling needle comprises a hollow puncturing tube, wherein the interior of the hollow puncturing tube is sleeved with a cutter; a sampling hole is formed in the tube wall at the front end of the hollow puncturing tube; the cutter is a tubular cutter; a cutting edge is arranged at the front end of the cutter; the cutter adopts a hollow cylinder structure; the tail of the cutter is connected to a negative pressure generation device; the front end of the hollow puncturing tube is a solid tip structure. Samples sunken in the sampling hole are separated from a body when the cutter is inserted; the samples are small in wound area and simple and convenient to cut; the tail of the cutter is connected to the negative pressure generation device; the cutter is capable of adsorbing and extracting the samples separated from the body; the end of the hollow puncturing tube is the solid tip structure, so that the hollow puncturing tube is capable of effectively preventing the samples from dropping out of a needle body area; meanwhile, due to the adoption of a solid tip, so that the end surface is smooth, and the puncture is facilitated. Through the living tissue puncturing and sampling needle, the problems of large wound area and incapability of multiple sampling with one puncturing during sampling via the existing tissue puncturing and sampling needle can be solved.

Description

A kind of biological tissue punctures sampling probe
Technical field
The present invention relates to living body sampling equipment technical field, puncture sampling probe particularly to a kind of biological tissue.
Background technology
In clinical research and diagnosis, frequently with living body sampling method to will study or the position diagnosing is adopted Sample.I.e. to studying or the position analyzed or tissue are sampled, then the sample of taking-up is cultivated and checked, obtained There is cogency and targetedly result or conclusion.In the application extracting a small amount of sample, living body sampling pin is a kind of important Apparatus, because its wound surface is little, flexible operation is widely accepted.
Existing Chinese patent CN201010154334.6 provides a kind of biopsy needle group puncturing active organization's inspection for bone Close, including solid puncture needle, there is the hollow pipe sampling probe of cone tubular front end, the cutting parallel to needle tubing axle in needle wall Face opening, and located at section opening one edge needle tubing circumference tangentially extending go out cutter.
But above-mentioned technology, using complex, needs for solid puncture needle to coordinate insertion group with service aisle sleeve pipe first Knit, solid puncture needle is taken out;Then hollow pipe sampling probe is inserted from service aisle tail end of conduit, rotate hollow pipe sampling probe Make purpose sample and separate tissue, after extracting hollow pipe sampling probe, draw its internal sample with copper bar.This technical operation is complicated, And draw its internal sample distance farther out with copper bar, damage is likely to result in sample.
Content of the invention
It is an object of the invention to provide a kind of biological tissue punctures sampling probe, solve existing tissue penetration sampling probe sampling When wound big and can not the many sub-samplings of one-time puncture problem.
For achieving the above object, reach above-mentioned technique effect, the present invention solves the above problems by the following technical programs:
A kind of biological tissue punctures sampling probe, including hollow puncture tube, suit sickle in described hollow puncture tube pipe;Institute Thief hole is offered on the tube wall stating hollow puncture tube front end;Put the first edge on a knife or a pair of scissors in described sickle front end.
Ring set type sampling probe of the present invention, outer layer is hollow puncture tube, and internal layer is sickle.The tube wall of hollow puncture tube front end On offer thief hole, hollow puncture tube is punctured into lesion tissue position, due to the interaction between pressure and tissue, part Lesion tissue can be sunk in the shrinkage pool of thief hole.Treat that hollow puncture tube is placed to finish, using sickle, the tissue of in the hole is carried out Cutting, is realized sample and is separated with body.The more existing method that cutter are extended to the outside rotary-cut focus of hollow pipe of this method, cuts Cut speed fast, wound face is little.
Puncture the improvement of sampling probe as a kind of above-mentioned biological tissue of the present invention, described sickle is tubular cutter, cuts Put the first edge on a knife or a pair of scissors in the front end of cutter.Sickle is set to the tubular structure putting the first edge on a knife or a pair of scissors in front end, caliber is mated with hollow puncture bore, cutting The cutting to lesion tissue in thief hole can be completed during cutter reach, be not required to many more manipulations.
Puncture the improvement of sampling probe as a kind of above-mentioned biological tissue of the present invention, described sickle adopts hollow cylinder to tie Structure, afterbody connects negative pressure generating device.Tissue after cutting is located in sickle or end, and the negative pressure connecting in afterbody generates dress Put under effect, using the sucking action of negative pressure, cut down sample will be mobile or be adsorbed in sickle to sickle afterbody The mouth of pipe, takes out sickle in hollow puncture tube and can obtain sample tissue.So, can be in the feelings not taking out hollow puncture tube Repeat under condition and complete above-mentioned sampling operation.
Puncture the improvement of sampling probe as a kind of above-mentioned biological tissue of the present invention, described negative pressure generating device includes open circles The negative pressure cylinder of rod structure, in negative pressure cylinder cylinder, slidable connection is fixedly arranged at the front end with the core bar of plug.Negative pressure is less than the gas of normal pressure Pressure state, when container air pressure inside is changed into negative pressure from normal pressure, the pressure reduction between available external atmosphere pressure and this negative pressure is made With reaching the purpose adsorbing object.The negative pressure maker that the present invention adopts is identical with syringe principle, using core bar front end Negative pressure cylinder is closed by plug, and while pulling out core bar, the air pressure inside of negative pressure cylinder and sickle is changed into negative pressure from normal pressure, Produce adsorption, realize the purpose of sickle front end adsorption sample.
Puncture the improvement of sampling probe as a kind of above-mentioned biological tissue of the present invention, described hollow puncture tube front end is solid point Header structure.When not opening negative pressure maker, it is located at sickle front end or port via the sample that cutter cuts are got off, adopts Opening syringe needle, sample may drop out needle body region, leads to extract difficulty.Sample can be protected using solid tip, with When also sickle can be positioned.Further, puncture needle end face can be kept smooth using solid prong structure, be conducive to wearing Thorn operation.
Puncture the improvement of sampling probe as a kind of above-mentioned biological tissue of the present invention, described thief hole is arc shrinkage pool.Focus Tissue forms convex surface due to the impact of internal pressure and cell-cell interaction in sampling in the hole, and design arcuation shrinkage pool can make more Tissue enter groove in, after also can avoiding pathological changes simultaneously harder tissue cannot be introduced into thief hole situation occur.
The invention has the beneficial effects as follows:
1st, will sink into the sample in thief hole and separate with body while inserting sickle, more existing cutter are extended To the outside rotary-cut focus of hollow pipe, wound face is little, and cutting technique is easy.
2nd, sickle afterbody connects negative pressure generating device, and sickle can be adsorbed to the sample after being separated with body, with Sickle removes from hollow puncture tube and obtains, and may be implemented in and does not take out multiple repairing weld in the case of hollow puncture tube.
3rd, hollow puncture tube front end is solid prong structure, can effectively prevent sample from dropping out needle body region.Meanwhile, using reality Apex of the heart header structure can keep end face smooth, beneficial to puncture.
The present invention can preferably solve during the sampling of existing tissue penetration sampling probe that wound is big and can not the many sub-samplings of one-time puncture Problem.
Brief description
Fig. 1 is that a kind of biological tissue punctures sampling probe profile;
Fig. 2 is hollow puncture tube schematic diagram;
Fig. 3 is sickle schematic diagram;
Fig. 4 is negative pressure generating device schematic diagram.
Figure number identifies:10th, hollow puncture tube, 11, thief hole, 12, handle, 20, sickle, 21, sword, 22, base, 30, Negative pressure maker, 31, negative pressure cylinder, 32, plug, 33, core bar.
Specific embodiment
The invention will be further described with reference to embodiments, but the invention is not limited in following examples.
Described in this example, a kind of biological tissue punctures sampling probe, and as shown in Figure 1, needle body is column type ring set structure, interior Portion is the sickle 20 of tubulose, and outside is hollow puncture tube 10.As shown in Figures 1 and 2, outside hollow puncture tube 10 is The hollow structure of afterbody opening, front end is solid prong structure, can be used for puncturing skin or tissue divots.Before hollow puncture tube 10 The pipe wall position at end offers arc thief hole 11, and afterbody is provided with ring-shaped handle 12.Using cabochon shrinkage pool thief hole 11, just It is absorbed in lesion tissue.
As shown in accompanying drawing 1 and accompanying drawing 3, sickle 20 is similarly open column shape pipe 10, and mouth of pipe annular end face puts the first edge on a knife or a pair of scissors 21, is used for Cutting dents into the lesion tissue in thief hole 11.Sickle 20 tail end arranges ring-type base 22, base 22 and sickle 20 Central axes.
As shown in accompanying drawing 1 and accompanying drawing 4, be connected with sickle 20 rear end base is the negative pressure cylinder of negative pressure generating device 30 31, negative pressure cylinder 31 inner slidable is connected with plug 32, and plug 32 radial shape is identical with the internal diameter of negative pressure cylinder 31 with size, can The space of plug 32 front side effectively in closed negative pressure cylinder 31.This example, using double-deck plug 32, can effectively completely cut off in negative pressure cylinder 31 The gas of both sides in front and back.Plug 32 afterbody axial location is fixedly connected with core bar 33, and under the drive of core bar 33, plug 32 is realized Move along negative pressure cylinder 31 axis direction, thus reaching the purpose adjusting 31 internal gas pressures of negative pressure cylinder.
The operation principle of the present embodiment is:
First open column shape pipe 10 is punctured into targeted site position, after will be connected to the sickle of negative pressure generating device 30 In the pipe box of 20 insertion open column shape pipes 10, complete the cutting of sample.Now the plug 32 of negative pressure maker 30 is located at negative pressure cylinder The front end of 31 inwalls.
The sword 21 of cutter 20 front end to be cut reaches inside the solid tip of open column shape pipe 10, keeps open column shape pipe 10th, in the case that sickle 20, negative pressure cylinder 31 relative position are constant, pull back core bar 33, drive plug 32 along axis side It is moved back by 1/3~2/3 distance.Make to be in negative pressure state inside negative pressure cylinder 31 and sickle 20, now can be to sickle 20 end Sample produce absorption.
Finally, sickle 20 and negative pressure maker 30 are taken out in open column shape pipe 10, required target sample is located at and cuts Cutter 20 inside or endface position, promote core bar 33 along axis direction, release negative pressure state, make sample and 20 points of sickle From acquisition sample to be studied.
Above in association with accompanying drawing, embodiments of the present invention are described in detail, but the present invention is not limited to described embodiment party Formula.For a person skilled in the art, without departing from the principles and spirit of the present invention to these embodiments Carry out multiple changes, modification, replacement and modification to still fall within protection scope of the present invention.

Claims (6)

1. a kind of biological tissue punctures sampling probe, including hollow puncture tube (10) it is characterised in that:Described hollow puncture tube (10) Suit sickle (20) in pipe;Thief hole (11) is offered on the tube wall of described hollow puncture tube (10) front end.
2. a kind of biological tissue according to claim 1 puncture sampling probe it is characterised in that:Described sickle (20) is pipe Shape sickle, put the first edge on a knife or a pair of scissors in the front end of sickle (21).
3. a kind of biological tissue according to claim 1 puncture sampling probe it is characterised in that:Described sickle (20) adopts Hollow cylinder structure, afterbody connects negative pressure generating device (30).
4. a kind of biological tissue according to claim 3 puncture sampling probe it is characterised in that:Described negative pressure generating device (30) include the negative pressure cylinder (31) of hollow cylinder structure, in negative pressure cylinder (31) cylinder, slidable connection is fixedly arranged at the front end with plug (32) Core bar (33).
5. a kind of biological tissue according to claim 1 puncture sampling probe it is characterised in that:Described hollow puncture tube (10) Front end is solid prong structure.
6. a kind of biological tissue according to any one of Claims 1 to 5 puncture sampling probe it is characterised in that:Described Thief hole (11) is arc shrinkage pool.
CN201610869544.0A 2016-09-28 2016-09-28 Living tissue puncturing and sampling needle Pending CN106388872A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610869544.0A CN106388872A (en) 2016-09-28 2016-09-28 Living tissue puncturing and sampling needle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610869544.0A CN106388872A (en) 2016-09-28 2016-09-28 Living tissue puncturing and sampling needle

Publications (1)

Publication Number Publication Date
CN106388872A true CN106388872A (en) 2017-02-15

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Country Status (1)

Country Link
CN (1) CN106388872A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106895989A (en) * 2017-03-31 2017-06-27 董成功 Biological tissue samples pathological study instrument
CN107411782A (en) * 2017-05-12 2017-12-01 张颖 A kind of oncology chemicotherapy treatment pipe device
CN107536628A (en) * 2017-10-11 2018-01-05 北京柏惠维康科技有限公司 Sampler
CN109247957A (en) * 2018-10-26 2019-01-22 陈菁 percutaneous puncture catheter needle
CN109303575A (en) * 2017-07-26 2019-02-05 株式会社岛津制作所 Needle biopsy device, needle biopsy and needle biopsy system
CN109528244A (en) * 2018-12-28 2019-03-29 河南农业大学 Living body sampler and drill bit suitable for the living body sampler

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Publication number Priority date Publication date Assignee Title
CN1722986A (en) * 2002-12-11 2006-01-18 伊西康内外科公司 Biopsy device with sample tube
CN1827050A (en) * 2005-03-04 2006-09-06 伊西康内外科公司 Biopsy device incorporating an adjustable probe sleeve
CN101032419A (en) * 2006-03-07 2007-09-12 伊西康内外科公司 Device for minimally invasive internal tissue removal
CN103096814A (en) * 2010-09-10 2013-05-08 德威科医疗产品公司 Biopsy device tissue sample holder with removable tray
US20150190124A1 (en) * 2005-01-31 2015-07-09 C. R. Bard, Inc. Quick cycle biopsy system
CN205163116U (en) * 2015-08-14 2016-04-20 李勇 Tumor sampling device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1722986A (en) * 2002-12-11 2006-01-18 伊西康内外科公司 Biopsy device with sample tube
US20150190124A1 (en) * 2005-01-31 2015-07-09 C. R. Bard, Inc. Quick cycle biopsy system
CN1827050A (en) * 2005-03-04 2006-09-06 伊西康内外科公司 Biopsy device incorporating an adjustable probe sleeve
CN101032419A (en) * 2006-03-07 2007-09-12 伊西康内外科公司 Device for minimally invasive internal tissue removal
CN103096814A (en) * 2010-09-10 2013-05-08 德威科医疗产品公司 Biopsy device tissue sample holder with removable tray
CN205163116U (en) * 2015-08-14 2016-04-20 李勇 Tumor sampling device

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106895989A (en) * 2017-03-31 2017-06-27 董成功 Biological tissue samples pathological study instrument
CN107411782A (en) * 2017-05-12 2017-12-01 张颖 A kind of oncology chemicotherapy treatment pipe device
CN109303575A (en) * 2017-07-26 2019-02-05 株式会社岛津制作所 Needle biopsy device, needle biopsy and needle biopsy system
US10980497B2 (en) 2017-07-26 2021-04-20 Shimadzu Corporation Needle biopsy apparatus, needle biopsy method, and needle biopsy system
CN107536628A (en) * 2017-10-11 2018-01-05 北京柏惠维康科技有限公司 Sampler
CN109247957A (en) * 2018-10-26 2019-01-22 陈菁 percutaneous puncture catheter needle
CN109528244A (en) * 2018-12-28 2019-03-29 河南农业大学 Living body sampler and drill bit suitable for the living body sampler

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