CN106372432A - Medicine combination information processing method - Google Patents

Medicine combination information processing method Download PDF

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Publication number
CN106372432A
CN106372432A CN201610799305.2A CN201610799305A CN106372432A CN 106372432 A CN106372432 A CN 106372432A CN 201610799305 A CN201610799305 A CN 201610799305A CN 106372432 A CN106372432 A CN 106372432A
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China
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information
medicine
drug regimen
doctor
drug
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CN201610799305.2A
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吕良忠
范辉
张玉瑛
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Hangzhou Yi Yao Information Technology Co Ltd
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Hangzhou Yi Yao Information Technology Co Ltd
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Priority to CN201610799305.2A priority Critical patent/CN106372432A/en
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Abstract

The invention relates to a medicine combination information processing method, which comprises the following steps of 1, generating medical advice information, wherein the medical advice information comprises medicine combination information; 2, extracting the medicine combination information from the medical advice information; 3, inquiring the medicine combination information from a medicine reasonable use database; 4, generating inquiry result information. The processing method of the medicine combination information provided by the invention has the advantages that the process of performing reasonableness inspection by a prescription-checking pharmacist through brain memory or literature and guide look-up on the complicated medicine use schemes is completed through computer software, so that the manual checking is changed into automatic checking; the checking efficiency on the specific medicine combination medical advice is greatly improved; the medicine use errors due to memory mistakes and familiar condition of the pharmacists to the medication schemes can be avoided; the medicine use safety of patients is ensured to the maximum degree.

Description

The processing method of drug regimen information
Technical field
The present invention relates to a kind of information processing method, more particularly, to a kind of processing method of drug regimen information.
Background technology
With the development of medical skill, the medicine that can be used to carry out disease treatment gets more and more, by this clinical practice Treatment for some diseases generally has multiple therapeutic schemes, particularly in Drug therapy and the nutritional support treatment of tumor In, these schemes typically form a kind of drug regimen by two or more medicines, from single medicine using different, these schemes There is strict regulation to the indication of this pharmaceutical admixtures or combination, drug dose, the course for the treatment of and compatibility etc..In addition, nutritional support Drug regimen total parenteral nutrition liquid (total parenteral nutrition, tpn) in treatment is multiple due to its composition Miscellaneous, affected by ph, cation concn, other drugs, preparation order etc., be that clinical safety requires highest, need One of venous transfusion to be paid close attention to.
Examination & verification for drug regimen can only be the inefficiency by manually carrying out at present, and it is wrong examination & verification easily By mistake, thus affecting medication effect, it is unfavorable for that patient gets well.
Content of the invention
It is an object of the invention to provide a kind of processing method of drug regimen information, to solve manual examination and verification drug regimen effect Rate is low, and the problem of mistake easily.
For achieving the above object, the invention provides a kind of processing method of drug regimen information, comprising:
Step 1, generates doctor's advice information, and described doctor's advice information includes drug regimen information;
Step 2, extracts described drug regimen information from described doctor's advice information;
Step 3, inquires about described drug regimen information from rational application of medicine data base;
Step 4, generates Query Result information.
Further, described drug regimen information includes multiple medicine informations, dosage information, administrated method letter Breath.
Further, described step 1 specifically includes: specification drug regimen module, according to the diagnostic message receiving, is inquired about Corresponding drug regimen information list in described diagnostic message, selects the first drug regimen from described drug regimen information list Information, generates described doctor's advice information according to described first drug regimen information.
Further, described drug regimen information list generates according to treatment guidelines and evidence-based medicine EBM foundation.
Further, the drug regimen in described drug regimen information list sorts according to priority orders.
Further, described step 3 specifically includes: using the logical judgment rule in described rational application of medicine data base Then, state of an illness information, drug administration information are carried out judging whether to meet.
Further, described state of an illness information includes: the age, sex, height, body weight, allergy medicine, staging typing, Liver function, renal function, whether pregnancy, whether suckling, pregnancy period and information of whether dialysing;Described drug administration information include administration frequency, Route of administration, each dosage, delivery time, the dosage period/course for the treatment of, daily dosage, solvent type and consumption information.
Further, described step 4 specifically includes: generates described first drug regimen information and whether there is non-rational use of drug Situation information, and send alarm prompt.
Further, also include after described step 4: step 5, according to described alarm prompt, generate doctor's advice again Information, execution step 2.
Further, described rational application of medicine data base includes: package insert information, clinical application notice information and Clinical therapeutic guideline information.
The processing method of the drug regimen information that the present invention provides, originally will rely on brain memory by careful side pharmacist or borrow Consulting literatures are helped to complete complicated therapeutic regimen is carried out the process of reasonableness check with guide by computer software Lai complete Become, make examination & verification from being manually changed into automatic, drastically increase the review efficiency that specific drugs are combined with doctor's advice, be reduced as far as Medication errors dosage regimen is unfamiliar with and is led to due to mistake and the pharmacist of memory, have farthest ensured the use of patient Medicine safety.
Brief description
Fig. 1 is the process flow figure of drug regimen information provided in an embodiment of the present invention.
Specific embodiment
Below by drawings and Examples, technical scheme is described in further detail.
Due to not coming for drug regimen or for specific drugs combination as an entirety in currently available technology Audited, therefore the invention provides a kind of carry out personalisation process for the combination of these specific drugs, and data statisticss Reasonable employment examination & verification ways and means, can accurately and efficiently find drug regimen medication that may be present problem.
Fig. 1 is the flow chart of the processing method of drug regimen information of the present invention, as shown in figure 1, the present invention includes walking as follows Rapid:
Step 1, generates doctor's advice information, and described doctor's advice information includes drug regimen information.
Specifically, specification drug regimen module, according to the diagnostic message receiving, inquires about corresponding medicine in diagnostic message Combined information list, selects the first drug regimen information from drug regimen information list, is given birth to according to the first drug regimen information Become doctor's advice information.Drug regimen information includes multiple medicine informations, dosage information, administrated method information.
Wherein, the first drug regimen is the specific drugs combination needing to be examined.Drug regimen information list is according to controlling Treat guide and evidence-based medicine EBM to generate according to information.Drug regimen in drug regimen information list sorts according to priority orders. The confirmation of priority can be self-defining, or is determined according to the order of medication guide suggestion.
This step is exactly the generating mode of doctor's advice information, and concrete methods of realizing is as follows:
Implementation method one: specification drug regimen module provides by veteran medicine and pharmacology expert according to up-to-date both at home and abroad Treatment guidelines and evidence-based medicine EBM are according to the different pharmaceutical combined information list determining, the diagnosis that specification drug regimen module receives After information, the diagnosis according to patient selects specific drug regimen in drug regimen information list, by determining drug regimen In every kind of medicine usage and dosage after, generate doctor's advice information.
Implementation method two: to the medicine belonging in specific drugs assembled scheme in up-to-date treatment guidelines and evidence-based medicine EBM foundation Give special label, directly these are classified as specific drugs composition of medicine with special tag medicine, generate doctor's advice information.
Step 2, extracts described drug regimen information from described doctor's advice information.
Specifically, doctor's advice information is parsed, thus obtaining drug regimen information.
Step 3, inquires about described drug regimen information from rational application of medicine data base.
Specifically, using the logical judgment rule in rational application of medicine data base, state of an illness information, drug administration information are carried out Judge whether to meet.
Wherein, rational application of medicine data base includes: package insert information, clinical application notice information and clinical treatment Guide information.
State of an illness information includes: the age, sex, height, body weight, allergy medicine, staging typing, liver function, renal function, Whether pregnancy, whether suckling, pregnancy period and information of whether dialysing;Described drug administration information include administration frequency, route of administration, every time to Pharmaceutical quantities, delivery time, the dosage period/course for the treatment of, daily dosage, solvent type and consumption information.
Because the therapeutic regimen from up-to-date treatment guidelines and evidence-based medicine EBM both at home and abroad is typically by two or more medicine shapes Become a kind of drug regimen, the use with single medicine has bigger difference, it uses and there may be problems with preparation aspect, Need to carry out medication reasonability examination.If being completely dependent on manual examination and verification, workload is big and because pharmacist's professional standards are uneven, It is difficult to ensure the drug safety of patient completely it is therefore desirable to using package insert, clinical application notice, treatment guidelines etc. as special The Knowledge Source of different drug regimen rational use of drug appraisement system, all factors relevant with judging rational use of drug are organized in one Rise, in the form of logical judgment rule, set up rational application of medicine data base.
Drug regimen information, the critical thinking mode of simulation clinical rational drug use expert, root is extracted from doctor's advice information According to the logical judgment rule set up in rational application of medicine data base, the results such as patient information, drug administration information are carried out comprehensively sentence Disconnected, show that this drug regimen doctor's advice whether there is possible non-rational use of drug situation.
Step 4, generates Query Result information.
Specifically, generate the first drug regimen information and whether there is non-rational use of drug situation information, and send alarm prompt Information.Warning information can be pointed out according to alarm level, for example, pass through different colours prompt alarm rank;Can also pass through Word message representing alarm level, for example, absolutely not can use, advise not using, advising cautiously using etc..
Also include after step 4: step 5, according to alarm prompt, generate doctor's advice information, execution step 2 again.
If there is non-rational use of drug situation, after producing alarm prompt, it is shown in pharmacists ' job platform, by pharmacist Carry out secondary examination & verification, and auditing result is fed back to doctor, decide whether to adjust medication information by doctor, generate doctor's advice letter again Breath, enters the specific drugs composite reagent reasonability review procedure of next round.
Examine side pharmacist as follows to the feedback specific implementation of evolution doctor:
Implementation method one: doctor's doctor's advice platform not prompt alarm information, pharmacist is directly by modes such as short words, notes Doctor's advice auditing result is informed doctor, after confirming with doctor, decides whether to modify doctor's advice or further confirm that doctor's advice Enter allocation process.
Implementation method two: doctor's doctor's advice platform not display alarm information in advance, after pharmacist's examination & verification, then by with doctor The interface caused trouble, auditing result is returned doctor terminal, is judged by doctor, determines modification doctor's advice or provides specific reason continuation Execute allotment.
Implementation method three: doctor's doctor's advice platform prompt alarm information, the use changing in doctor's advice of being maked decision by doctor Medicine information or be given specific reason continue executing with doctor's advice preserve.After entering pharmacist's examination & verification platform, show at pharmacist's examination & verification interface simultaneously Show the reasons why alarm prompt and doctor, then reasonability is judged by careful side pharmacist.
Concrete example is as follows:
Doctor's advice information for the mfolfox6 scheme in treatment of colon cancer is as follows:
Oxaliplatin 85mg/m2, iv (venoclysises), d1;
Calcium folinate 400mg/m2, iv (venoclysises), d1;
5-fluorouracil 400mg/m2, iv bolus (intravenous injection), d1;
Subsequently 1200mg/m2/ d × 2 day, (amount to 2400mg/m in 46-48 hour2) Intravenous Infusion, every 2 weeks repeat;
It is made up of the mfolfox6ization finished in intestinal cancer treatment oxaliplatin, calcium folinate and three kinds of medicines of 5-fluorouracil The specific drugs combined information for the treatment of scheme.
Using program patient basis: man, 56 years old, body weight 62kg, height 170cm, body surface area (bsa) 1.75m2, kps80.Medicine-less allergy history.
The logical judgment rule that may use:
1st, patient is to three kinds of medicines all no allergy;
2nd, kps > 70 just can give chemotherapy;
3rd, patient's routine blood test result: if first time chemotherapy, neutrophil count < 2 × 109/ l, or platelet meter Number < 100 × 109/ l is it is proposed that prohibit the use of;In remaining chemotherapy process, neutrophil count < 1.5 × 109/ l, or leukocyte meter Number < 2 × 109/ l, or platelet count < 50 × 109/ l, it is proposed that prohibitting the use of, postpones chemotherapy;
If < 30ml/ divides 4 patient's creatinine clearance rates (ccr), disabling;
5th, calculate by patient body surface areas 1.75m2 and determine three kinds of drug administration dosage;
6th, three kinds of drug administration frequencies are single-dose, use on the same day;
7th, oxaliplatin must be diluted with 5% Glucose Injection 250-500ml;
8th, oxaliplatin and calcium folinate venoclysises are unsuitable fast, and the general instillation time should be greater than 2h.5-fluorouracil is held Continuous venoclysises time requirement 46-48 hour;
9th, oxaliplatin should use prior to 5-fu;
10th, two course for the treatment of interval times were 2 weeks.
Using the logical judgment rule in rational application of medicine data base, according to state of an illness information, drug administration information to special medicine Thing combination is judged, show that this drug regimen doctor's advice whether there is possible non-rational use of drug situation.Think rational, enter Allotment and dispensing flow process it is believed that irrational, pointed out unreasonable message in pharmacists ' job platform and doctor's doctor's advice platform respectively, are made Doctor can be known the unreasonable problem occurring in prescription in time and modify.
The processing method of the drug regimen information that the present invention provides, originally will rely on brain memory by careful side pharmacist or borrow Consulting literatures are helped to complete complicated therapeutic regimen is carried out the process of reasonableness check with guide by computer software Lai complete Become, make examination & verification from being manually changed into automatic, drastically increase the review efficiency that specific drugs are combined with doctor's advice, be reduced as far as Medication errors dosage regimen is unfamiliar with and is led to due to mistake and the pharmacist of memory, have farthest ensured the use of patient Medicine safety.
Professional should further appreciate that, each example describing in conjunction with the embodiments described herein Unit and algorithm steps, can be hard in order to clearly demonstrate with electronic hardware, computer software or the two be implemented in combination in Part and the interchangeability of software, generally describe composition and the step of each example in the above description according to function. These functions to be executed with hardware or software mode actually, the application-specific depending on technical scheme and design constraint. Professional and technical personnel can use different methods to each specific application realize described function, but this realization It is not considered that it is beyond the scope of this invention.
The step of the method in conjunction with the embodiments described herein description or algorithm can be with hardware, computing device Software module, or the combination of the two is implementing.Software module can be placed in random access memory (ram), internal memory, read only memory (rom), electrically programmable rom, electrically erasable rom, depositor, hard disk, moveable magnetic disc, cd-rom or technical field In interior known any other form of storage medium.
Above-described specific embodiment, has been carried out to the purpose of the present invention, technical scheme and beneficial effect further Describe in detail, be should be understood that the specific embodiment that the foregoing is only the present invention, be not intended to limit the present invention Protection domain, all any modification, equivalent substitution and improvement within the spirit and principles in the present invention, done etc., all should comprise Within protection scope of the present invention.

Claims (10)

1. a kind of processing method of drug regimen information is it is characterised in that methods described includes:
Step 1, generates doctor's advice information, and described doctor's advice information includes drug regimen information;
Step 2, extracts described drug regimen information from described doctor's advice information;
Step 3, inquires about described drug regimen information from rational application of medicine data base;
Step 4, generates Query Result information.
2. method according to claim 1 it is characterised in that described drug regimen information include multiple medicine informations, Dosage information, administrated method information.
3. method according to claim 1 is it is characterised in that described step 1 specifically includes: specification drug regimen module root According to the diagnostic message receiving, inquire about corresponding drug regimen information list in described diagnostic message, from described drug regimen letter Select the first drug regimen information in breath list, described doctor's advice information is generated according to described first drug regimen information.
4. method according to claim 3 is it is characterised in that described drug regimen information list according to treatment guidelines and follows Card medical science is according to generation.
5. method according to claim 3 it is characterised in that drug regimen in described drug regimen information list according to Priority orders sort.
6. method according to claim 1 is it is characterised in that described step 3 specifically includes: is rationally made using described medicine With the logical judgment rule in data base, state of an illness information, drug administration information are carried out judging whether to meet.
7. method according to claim 6 is it is characterised in that described state of an illness information includes: age, sex, height, body Weight, allergy medicine, staging typing, liver function, renal function, whether pregnancy, whether suckling, pregnancy period and information of whether dialysing; Described drug administration information include administration frequency, route of administration, each dosage, delivery time, the dosage period/course for the treatment of, daily to Pharmaceutical quantities, solvent type and consumption information.
8. method according to claim 1 is it is characterised in that described step 4 specifically includes: generates described first medicine group Conjunction information whether there is non-rational use of drug situation information, and sends alarm prompt.
9. method according to claim 8 is it is characterised in that also include after described step 4: step 5, according to described announcement Alert information, generates doctor's advice information, execution step 2 again.
10. method according to claim 1 is it is characterised in that described rational application of medicine data base includes: medicine explanation Letter breath, clinical application notice information and clinical therapeutic guideline information.
CN201610799305.2A 2016-08-31 2016-08-31 Medicine combination information processing method Pending CN106372432A (en)

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Cited By (10)

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CN106971083A (en) * 2017-05-11 2017-07-21 杭州逸曜信息技术有限公司 Medication information processing method based on test rating
CN107066826A (en) * 2017-05-11 2017-08-18 杭州逸曜信息技术有限公司 Medication information processing method based on test rating
CN107180157A (en) * 2017-05-11 2017-09-19 杭州逸曜信息技术有限公司 Medical information processing method
CN107705825A (en) * 2017-09-25 2018-02-16 南京市儿童医院 A kind of children's parenteral nutrition computational chart preparation method based on MicrosoftExcel
CN108538351A (en) * 2018-03-19 2018-09-14 杭州逸曜信息技术有限公司 Based on drug minimum can divided dose and routine dose medication information processing method
CN108538352A (en) * 2018-03-19 2018-09-14 杭州逸曜信息技术有限公司 Medication information processing method
CN111192650A (en) * 2019-12-25 2020-05-22 浙江大学 Prescription information pushing method and device based on parenteral nutrition and computer equipment
CN111986038A (en) * 2020-08-31 2020-11-24 平安医疗健康管理股份有限公司 Examination method, device, equipment and storage medium for diagnosis and treatment behaviors of single disease
CN113813478A (en) * 2021-10-11 2021-12-21 河南省儿童医院郑州儿童医院 Automatic control method and system for drug delivery of atomizer
CN115312205A (en) * 2022-10-11 2022-11-08 四川省医学科学院·四川省人民医院 Single-disease clinical path management system

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CN106971083A (en) * 2017-05-11 2017-07-21 杭州逸曜信息技术有限公司 Medication information processing method based on test rating
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CN111192650B (en) * 2019-12-25 2021-07-30 浙江大学 Prescription information pushing method and device based on parenteral nutrition and computer equipment
CN111986038A (en) * 2020-08-31 2020-11-24 平安医疗健康管理股份有限公司 Examination method, device, equipment and storage medium for diagnosis and treatment behaviors of single disease
CN113813478A (en) * 2021-10-11 2021-12-21 河南省儿童医院郑州儿童医院 Automatic control method and system for drug delivery of atomizer
CN115312205A (en) * 2022-10-11 2022-11-08 四川省医学科学院·四川省人民医院 Single-disease clinical path management system

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Application publication date: 20170201