CN106362098A - Traditional Chinese medicine preparation for treating liver-yang adverse rising and preparation method - Google Patents

Traditional Chinese medicine preparation for treating liver-yang adverse rising and preparation method Download PDF

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CN106362098A
CN106362098A CN201610992116.7A CN201610992116A CN106362098A CN 106362098 A CN106362098 A CN 106362098A CN 201610992116 A CN201610992116 A CN 201610992116A CN 106362098 A CN106362098 A CN 106362098A
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parts
radix
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chinese medicine
medicine preparation
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黄烜
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Dongguan Biological Technology Co Ltd
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Dongguan Biological Technology Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating liver-yang adverse rising and a preparation method. The traditional Chinese medicine preparation is prepared from, by weight, 90-150 parts of rhizoma gastrodiae, 200-400 parts of ramulus uncariae cum uncis, 200-400 parts of stir-fried jujube kernels, 170-230 parts of radix polygoni multiflori preparata, 170-230 parts of white peony roots, 170-230 parts of semen cassiae, 170-230 parts of radix glehniae, 200-400 parts of milkvetch roots, 120-180 parts of radix curcumae, 120-180 parts of barbary wolfberry fruit, 120-180 parts of polygala roots, 90-150 parts of lucid ganoderma, 40-80 parts of licorice roots, 50-110 parts of perilla leaves, 90-150 parts of earthworms, 90-150 parts of cornu saigae tataricae, 0.001-0.002 part of Acesulfame, 0.001-0.002 part of sodium benzoate and 0.001-0.0016 part of essence. The traditional Chinese medicine preparation has the effects of calming the liver, suppressing yang, nourishing yin and soothing the nerves and is exact in treatment effect, high in effective rate, safe and poisonless.

Description

A kind of Chinese medicine preparation treating liver-Yang hyperactivity card and preparation method
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine preparation treating liver-Yang hyperactivity card and preparation method.
Background technology
Liver-Yang hyperactivity is demonstrate,proved, and Chinese medical disease name refers to due to hepatic and renal YIN deficiency, and liver-yang is high to disturb in upper showed excess in the upper and deficiency in the lower card Wait, also known as excessive rising of liver-YANG, excess of liver-YANG, the cause of disease is angry to be hindered, stagnated QI transforming into fire, burning hot the moon consuming impairing the liver kidney, or hindered because of exhaustion due to sexual indulgence, Old deficiency of kidney-YIN, the kidney failing to nourish the liver, edema with the liver involved cervical carcinoma with cachexia, pathogenesis is many, and because of the hepatic and renal YIN deficiency, the moon does not contain sun, so that liver-yang rises moving too；Or Because of disgruntled anxiety, stagnated QI transforming into fire, consume impairment of YIN blood, the moon sun not processed forms, the dialectical vertigo to be put, distending pain, top-heavy, waist and knee Aching and limp, red tongue with a little fluid, stringy pulse or stringy and thready pulse number；At present, Chinese medicine liver-Yang hyperactivity card research report is increasing, because its pair is made Accepted by vast liver-Yang hyperactivity card patient with little, but made a general survey of Recent study overview, remained in many problems, such as decoction adds The person of subtracting is many, and fixed dosage form person is few etc., particularly the animal experiment study of the aspects such as mechanism of drug action, link is not yet appeared in the newspapers Road, in view of this, using modern science and technology equipment and method, inquires into liver-Yang hyperactivity card etiology and pathogenesis, screening verification active drug, grinds The Chinese medicine preparation that system is with strong points, curative effect affirmative, dosage form are easy, is key issue currently urgently to be resolved hurrily.
Content of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of taking convenience, be easy to carry, the controlling of easy long term usage Treat Chinese medicine composition and the preparation method of liver-Yang hyperactivity card, this Chinese medicine preparation has functions that suppressing the hyperactive liver and subsiding YANG, nourishing YIN for tranquillization, curative effect Definitely, effective percentage is high, safety non-toxic.
For solving above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation treating liver-Yang hyperactivity card, by following weight The raw material of part is made: Rhizoma Gastrodiae 90-150 part, Ramulus Uncariae Cum Uncis 200-400 part, Semen Ziziphi Spinosae (parched) 200-400 part, Radix Polygoni Multiflori Preparata 170-230 part, the Radix Paeoniae Alba 170-230 part, Semen Cassiae 170-230 part, Radix Glehniae 170-230 part, Radix Astragali 200-400 part, Radix Curcumae 120-180 part, Fructus Lycii 120-180 part, Radix Polygalae 120-180 part, Ganoderma 90-150 part, Radix Glycyrrhizae 40-80 part, Folium Perillae 50-110 part, Pheretima 90-150 part, Cornu Saigae Tataricae 90-150 part, acesulfame potassium 0.001-0.002 part, sodium benzoate 0.001-0.002 part, essence 0.001-0.0016 part；
Its preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 50-80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200-300 mesh, obtains raw material powder, Standby；
(3) take 6-10 times that raw material Folium Perillae adds water as its weight, distillation time is 3-5 hour, the another device of the aqueous solution after distillation Collect, medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first use 30-50 DEG C water soak 30-50 minute, 10-14 times adding water as raw material gross weight, decoction 25-55 minute, pour out medicinal liquid, add water again For 5-8 times of raw material gross weight, decoct 25-55 minute, merge the aqueous solution after medicinal liquid and distillation, filter, be evaporated to 55- Survey the clear paste that relative density is 1.05-1.15 for 65 DEG C, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12-24 hour, fling to ethanol, after Filter, is further concentrated to 80-90 DEG C and surveys the extractum that relative density is 1.15-1.20, is placed in -5 to 0 DEG C of freezing 48-72 hours, standby With；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 200-300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6-9 times of its weight, agitator tank stirs 15- 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, add acesulfame potassium and sodium benzoate after pulverizing in filtrate, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, filtrate fill sterilizes, obtain final product treatment liver The Chinese medicine preparation of deteriorating syndrome on sun.
Preferably in scheme, a kind of Chinese medicine preparation treating liver-Yang hyperactivity card, it is made up of the raw material of following weight portion: Rhizoma Gastrodiae 120 parts, 300 parts of Ramulus Uncariae Cum Uncis, 300 parts of Semen Ziziphi Spinosae (parched), 200 parts of Radix Polygoni Multiflori Preparata, 200 parts of the Radix Paeoniae Alba, 200 parts of Semen Cassiae, 200 parts of Radix Glehniae, yellow 300 parts of stilbene, 150 parts of Radix Curcumae, 150 parts of Fructus Lycii, 150 parts of Radix Polygalae, 120 parts of Ganoderma, 60 parts of Radix Glycyrrhizae, 80 parts of Folium Perillae, Pheretima 120 Part, 120 parts of Cornu Saigae Tataricae, 0.0015 part of acesulfame potassium, 0.0015 part of sodium benzoate, 0.0013 part of essence；
Its preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200 mesh, obtains raw material powder, standby With；
(3) 10 times that raw material Folium Perillae adds water as its weight are taken, distillation time is 3 hours, and the another device of the aqueous solution after distillation is collected, Medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first with 40 DEG C of water logging Bubble 30 minutes, 10 times adding water as raw material gross weight, decoct 35 minutes, pour out medicinal liquid, add water again for raw material gross weight 8 Times, decoct 35 minutes, merge the aqueous solution after medicinal liquid and distillation, filter, being evaporated to 65 DEG C and surveying relative density is 1.05 Clear paste, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12 hours, fling to ethanol, refilter, then It is concentrated into 80 DEG C and surveys the extractum that relative density is 1.15, be placed in -5 DEG C and freeze 48 hours, standby；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6 times of its weight, in agitator tank, stir 15 points Clock, stands 4 hours, is stirred for 15 minutes, makes serosity flow into 360 mesh sieve hole reciprocating sieves while stirring and filters, obtains filtrate, to filtrate Acesulfame potassium and sodium benzoate after middle addition pulverizing, stirring adds essence after pulverizing after 20 minutes, is stirred for 20 minutes, finally 8 Stand 12 hours under conditions of DEG C, filter, filtrate fill sterilizes, obtain final product the Chinese medicine preparation for the treatment of liver-Yang hyperactivity card.
Used by the present invention, the pharmacology of raw material of Chinese medicine medicine is as follows:
Rhizoma Gastrodiae: meridian distribution of property and flavor: sweet, put down, return liver warp；Indication: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion；For dizziness of having a headache, numb limbs and tense tendons are little Youngster's infantile convulsion, epilepsy clonus, tetanus.
Ramulus Uncariae Cum Uncis: meridian distribution of property and flavor: sweet, cool, Return liver, pericardium channel；Indication: The flat liver of heat-clearing, dispelling wind and relieving convulsion；Dizzy for having a headache Dizzy, dysphoric cold, twitch, pre-eclampsia, hypertension.
Semen Ziziphi Spinosae (parched): meridian distribution of property and flavor: sweet, sour, put down, Return liver, gallbladder, heart channel；Indication: tonifying liver, mind calming, arresting sweating, promote the production of body fluid；With In restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, injury thirst.
Radix Polygoni Multiflori Preparata: nature and flavor: bitter, sweet, puckery, temperature, Return liver, the heart, kidney channel；Indication: invigorating the liver and kidney, benefiting essence-blood, black beard and hair, by force Muscles and bones；For for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void, Hyperlipidemia.
The Radix Paeoniae Alba: meridian distribution of property and flavor: bitter, sour, it is slightly cold, Return liver, spleen channel；Indication: smooth liver and relieve pain, nourishing blood for regulating menstruation, yin fluid astringing stops Antiperspirant；For dizziness of having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Semen Cassiae: meridian distribution of property and flavor: sweet, bitter, salty, it is slightly cold, Return liver, large intestine channel；Indication: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation； For the puckery pain of conjunctival congestion, the many tear of photophobia, dizziness of having a headache, poor vision, constipation.
Radix Glehniae: nature and flavor, sweet in the mouth, slight bitter, cold nature, return through, return lung, stomach；Indication: replenishing YIN and removing heat, lung moistening Expectorant, reinforcing stomach reg fluid, main yin chronic cough, consumptive disease is coughed expectorant blood, and cough caused by dryness expectorant is few, deficiency-heat sore throat, injury thirst.
The Radix Astragali: meridian distribution of property and flavor: sweet, temperature, return lung, spleen channel；Indication: invigorating QI to consolidate the body surface resistance, diuretic and maintain drug, evacuation of pus, sore is given birth to Flesh；For treatment deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult Burst, bursts for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic nephritis proteinuria, diabetes.
Radix Curcumae: meridian distribution of property and flavor: pungent, bitter, tremble with fear, Return liver, the heart, lung meridian；Indication: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, function of gallbladder promoting moves back Yellow；For closed dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice urine is red.
Fructus Lycii: meridian distribution of property and flavor: sweet, put down, return liver and kidney channel；Indication: nourishing the liver and kidney, replenishing vital essence to improve eyesight；For asthenia essence Lose, soreness of waist and knee joint, vertigo and tinnitus, Heat Diabetes, blood deficiency and yellow complexion, blurred vision.
Radix Polygalae: meridian distribution of property and flavor: bitter, pungent, warm, GUIXIN, kidney, lung meridian；Indication: tranquilize the mind and promote the intelligence, eliminating the phlegm, detumescence；For The insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Ganoderma: meridian distribution of property and flavor: sweet, put down, GUIXIN, lung, liver and kidney channel；Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, Malignant tumor etc..
Radix Glycyrrhizae: mild-natured, sweet in the mouth, GUIXIN, spleen, lung, stomach；Effect: tonification；Indication: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, Expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription；For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity Contraction urgency pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Folium Perillae: meridian distribution of property and flavor: pungent, temperature, return lung warp；Indication: sending down the abnormal ascending QI expectorant, relieving asthma, intestine moistening；Stop up gas for expectorant Inverse, cough and asthma, dry constipation of intestines.
Pheretima: meridian distribution of property and flavor: salty, tremble with fear, Return liver, spleen, bladder warp；Indication: heat clearing away arresting convulsion, dredging collateral, relieving asthma, diuresis； For unconsciousness due to high fever, twitch, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Cornu Saigae Tataricae: salty in the mouth, cold in nature, Return liver, heart channel；Effect: suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, scattered blood removing toxic substances；Cure mainly: be used for Liver-wind stirring up internally, twitch, pre-eclampsia, hyperpyrexia convulsion is fainted, and epilepsy is gone mad, dizziness of having a headache, cataract, maculae caused by violent heat pathogen, carbuncle Sore.
The invention has the benefit that having functions that suppressing the hyperactive liver and subsiding YANG, nourishing YIN for tranquillization, determined curative effect, effective percentage is high, safety Nontoxic.
Specific embodiment
Describe technical scheme with reference to embodiment and experimental example in detail, but protection domain not limited to this.
Embodiment 1
A kind of treat liver-Yang hyperactivity card Chinese medicine preparation, be made up of the raw material of following weight portion: 150 parts of Rhizoma Gastrodiae, 400 parts of Ramulus Uncariae Cum Uncis, 400 parts of Semen Ziziphi Spinosae (parched), 230 parts of Radix Polygoni Multiflori Preparata, 230 parts of the Radix Paeoniae Alba, 230 parts of Semen Cassiae, 230 parts of Radix Glehniae, 400 parts of the Radix Astragali, Radix Curcumae 180 Part, 180 parts of Fructus Lycii, 180 parts of Radix Polygalae, 150 parts of Ganoderma, 80 parts of Radix Glycyrrhizae, 110 parts of Folium Perillae, 150 parts of Pheretima, Cornu Saigae Tataricae 150 Part, 0.002 part of acesulfame potassium, 0.002 part of sodium benzoate, 0.0016 part of essence；
Its preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 50-80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200-300 mesh, obtains raw material powder, Standby；
(3) take 6-10 times that raw material Folium Perillae adds water as its weight, distillation time is 3-5 hour, the another device of the aqueous solution after distillation Collect, medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first use 30-50 DEG C water soak 30-50 minute, 10-14 times adding water as raw material gross weight, decoction 25-55 minute, pour out medicinal liquid, add water again For 5-8 times of raw material gross weight, decoct 25-55 minute, merge the aqueous solution after medicinal liquid and distillation, filter, be evaporated to 55- Survey the clear paste that relative density is 1.05-1.15 for 65 DEG C, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12-24 hour, fling to ethanol, after Filter, is further concentrated to 80-90 DEG C and surveys the extractum that relative density is 1.15-1.20, is placed in -5 to 0 DEG C of freezing 48-72 hours, standby With；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 200-300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6-9 times of its weight, agitator tank stirs 15- 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, add acesulfame potassium and sodium benzoate after pulverizing in filtrate, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, filtrate fill sterilizes, obtain final product treatment liver The Chinese medicine preparation of deteriorating syndrome on sun.
Usage: oral, 2 times a day, each 15ml.
Embodiment 2
A kind of treat liver-Yang hyperactivity card Chinese medicine preparation, be made up of the raw material of following weight portion: 120 parts of Rhizoma Gastrodiae, 300 parts of Ramulus Uncariae Cum Uncis, 300 parts of Semen Ziziphi Spinosae (parched), 200 parts of Radix Polygoni Multiflori Preparata, 200 parts of the Radix Paeoniae Alba, 200 parts of Semen Cassiae, 200 parts of Radix Glehniae, 300 parts of the Radix Astragali, Radix Curcumae 150 Part, 150 parts of Fructus Lycii, 150 parts of Radix Polygalae, 120 parts of Ganoderma, 60 parts of Radix Glycyrrhizae, 80 parts of Folium Perillae, 120 parts of Pheretima, 120 parts of Cornu Saigae Tataricae, 0.0015 part of acesulfame potassium, 0.0015 part of sodium benzoate, 0.0013 part of essence；
Its preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 50-80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200-300 mesh, obtains raw material powder, Standby；
(3) take 6-10 times that raw material Folium Perillae adds water as its weight, distillation time is 3-5 hour, the another device of the aqueous solution after distillation Collect, medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first use 30-50 DEG C water soak 30-50 minute, 10-14 times adding water as raw material gross weight, decoction 25-55 minute, pour out medicinal liquid, add water again For 5-8 times of raw material gross weight, decoct 25-55 minute, merge the aqueous solution after medicinal liquid and distillation, filter, be evaporated to 55- Survey the clear paste that relative density is 1.05-1.15 for 65 DEG C, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12-24 hour, fling to ethanol, after Filter, is further concentrated to 80-90 DEG C and surveys the extractum that relative density is 1.15-1.20, is placed in -5 to 0 DEG C of freezing 48-72 hours, standby With；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 200-300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6-9 times of its weight, agitator tank stirs 15- 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, add acesulfame potassium and sodium benzoate after pulverizing in filtrate, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, filtrate fill sterilizes, obtain final product treatment liver The Chinese medicine preparation of deteriorating syndrome on sun.
Usage: oral, 2 times a day, each 15ml.
Embodiment 3
A kind of Chinese medicine preparation treating liver-Yang hyperactivity card, is made up of the raw material of following weight portion: 90 parts of Rhizoma Gastrodiae, 200 parts of Ramulus Uncariae Cum Uncis, stir-fry 200 parts of Semen Ziziphi Spinosae, 170 parts of Radix Polygoni Multiflori Preparata, 170 parts of the Radix Paeoniae Alba, 170 parts of Semen Cassiae, 170 parts of Radix Glehniae, 200 parts of the Radix Astragali, 120 parts of Radix Curcumae, 120 parts of Fructus Lycii, 120 parts of Radix Polygalae, 90 parts of Ganoderma, 40 parts of Radix Glycyrrhizae, 50 parts of Folium Perillae, 90 parts of Pheretima, 90 parts of Cornu Saigae Tataricae, acesulfame potassium 0.001 part, 0.001 part of sodium benzoate, 0.001 part of essence；
Its preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 50-80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200-300 mesh, obtains raw material powder, Standby；
(3) take 6-10 times that raw material Folium Perillae adds water as its weight, distillation time is 3-5 hour, the another device of the aqueous solution after distillation Collect, medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first use 30-50 DEG C water soak 30-50 minute, 10-14 times adding water as raw material gross weight, decoction 25-55 minute, pour out medicinal liquid, add water again For 5-8 times of raw material gross weight, decoct 25-55 minute, merge the aqueous solution after medicinal liquid and distillation, filter, be evaporated to 55- Survey the clear paste that relative density is 1.05-1.15 for 65 DEG C, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12-24 hour, fling to ethanol, after Filter, is further concentrated to 80-90 DEG C and surveys the extractum that relative density is 1.15-1.20, is placed in -5 to 0 DEG C of freezing 48-72 hours, standby With；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 200-300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6-9 times of its weight, agitator tank stirs 15- 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, add acesulfame potassium and sodium benzoate after pulverizing in filtrate, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, filtrate fill sterilizes, obtain final product treatment liver The Chinese medicine preparation of deteriorating syndrome on sun.
Usage: oral, 2 times a day, each 15ml.
Traditional Chinese medicine composition for treating of the present invention observes liver-Yang hyperactivity card patient 45, and clinical report is as follows:
1st, physical data
Clinical observation liver-Yang hyperactivity demonstrate,proves patient 45, wherein male 20, female 25, age 20-65 year, 47.5 years old mean age.
2nd, diagnostic criteria
Symptoms include: liver-yang is high to disturb in upper, with dizziness ear toot, distending pain of the head and eyes, top-heavy, flushing conjunctival congestion, being irritable and getting angry easily, has a sleepless night many Dream, soreness of the waist and knees, bitter taste, red tongue stringy pulse.
3rd, Therapeutic Method
Using Chinese medicine preparation of the present invention treatment, take Chinese medicine preparation of the present invention, 2 times a day, each 15ml, 7 days is a course for the treatment of.
4th, efficacy evaluation
Cure: symptom, sign disappear substantially；
Take a turn for the better: symptom mitigation, sign is improved；
Invalid: symptom, sign are unchanged.
5th, therapeutic outcome
In clinical treatment liver-Yang hyperactivity card patient 45, cure 40 and account for 88.8%, take a turn for the better 5 and account for 11.2%, invalid 0, always have Efficiency is 100%.
6th, model case
Case 1: man, 22 years old, main suit: vexed, night rather sleeps, insomnia and dreamful sleep, soreness of the waist and knees, bitter taste, red tongue, and stringy pulse takes this One course for the treatment of of invention Chinese medicine preparation, patient symptom substantially mitigates, and takes one course for the treatment of of Chinese medicine preparation of the present invention again, and symptom is substantially good Turn, take two courses for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.
Case 2: man, 56 years old, main suit: dizzy, depending on thing rotation, tinnitus, lack of appetite, distending pain of the head and eyes, top-heavy, bitter taste, tongue Red, stringy pulse, take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom substantially mitigates, take Chinese medicine preparation of the present invention again The course for the treatment of, symptom is clearly better, and takes three courses for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.
Case 3: female, 40 years old, main suit: vertigo and tinnitus, distending pain of the head and eyes, top-heavy, being irritable and getting angry easily, insomnia and dreamful sleep, waist and knee Aching and limp, bitter taste, red tongue, stringy pulse, take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom substantially mitigates, and takes the present invention again One course for the treatment of of Chinese medicine preparation, symptom is clearly better, and takes two courses for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.
It should be pointed out that the specific embodiment more representational example that is the present invention is it is clear that the skill of the present invention Art scheme is not limited to above-described embodiment, can also have many variations；Those of ordinary skill in the art, clearly public with present invention institute What what written description that open or according to file was undoubted obtained, all it is considered as this patent scope of the claimed.

Claims (6)

1. a kind of treat liver-Yang hyperactivity card Chinese medicine preparation it is characterised in that: be made up of the raw material of following weight portion: Rhizoma Gastrodiae 90- 150 parts, Ramulus Uncariae Cum Uncis 200-400 part, Semen Ziziphi Spinosae (parched) 200-400 part, Radix Polygoni Multiflori Preparata 170-230 part, Radix Paeoniae Alba 170-230 part, Semen Cassiae 170- 230 parts, Radix Glehniae 170-230 part, Radix Astragali 200-400 part, Radix Curcumae 120-180 part, Fructus Lycii 120-180 part, Radix Polygalae 120-180 Part, Ganoderma 90-150 part, Radix Glycyrrhizae 40-80 part, Folium Perillae 50-110 part, Pheretima 90-150 part, Cornu Saigae Tataricae 90-150 part, acesulfame potassium 0.001-0.002 part, sodium benzoate 0.001-0.002 part, essence 0.001-0.0016 part.
2. according to claim 1 a kind of treat liver-Yang hyperactivity card Chinese medicine preparation preparation method it is characterised in that: its Preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 50-80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200-300 mesh, obtains raw material powder, Standby；
(3) take 6-10 times that raw material Folium Perillae adds water as its weight, distillation time is 3-5 hour, the another device of the aqueous solution after distillation Collect, medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first use 30-50 DEG C water soak 30-50 minute, 10-14 times adding water as raw material gross weight, decoction 25-55 minute, pour out medicinal liquid, add water again For 5-8 times of raw material gross weight, decoct 25-55 minute, merge the aqueous solution after medicinal liquid and distillation, filter, be evaporated to 55- Survey the clear paste that relative density is 1.05-1.15 for 65 DEG C, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12-24 hour, fling to ethanol, after Filter, is further concentrated to 80-90 DEG C and surveys the extractum that relative density is 1.15-1.20, is placed in -5 to 0 DEG C of freezing 48-72 hours, standby With；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 200-300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6-9 times of its weight, agitator tank stirs 15- 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, add acesulfame potassium and sodium benzoate after pulverizing in filtrate, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, filtrate fill sterilizes, obtain final product treatment liver The Chinese medicine preparation of deteriorating syndrome on sun.
3. according to claim 2 a kind of treat liver-Yang hyperactivity card Chinese medicine preparation preparation method it is characterised in that: its Preparation process is:
(1) take raw material Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Polygoni Multiflori Preparata, the Radix Paeoniae Alba, Semen Cassiae, Radix Glehniae, the Radix Astragali, Radix Curcumae, Fructus Lycii, remote Will, Radix Glycyrrhizae mixing, are ground into 80 mesh, obtain raw material powder, standby；
(2) raw material Ganoderma, Pheretima, Cornu Saigae Tataricae is taken to be pulverized after mixing, the fineness degree of pulverizing is 200 mesh, obtains raw material powder, standby With；
(3) 10 times that raw material Folium Perillae adds water as its weight are taken, distillation time is 3 hours, and the another device of the aqueous solution after distillation is collected, Medicinal residues mix decoction with the raw material powder after pulverizing in the raw material powder after pulverizing in step (1), step (2), first with 40 DEG C of water logging Bubble 30 minutes, 10 times adding water as raw material gross weight, decoct 35 minutes, pour out medicinal liquid, add water again for raw material gross weight 8 Times, decoct 35 minutes, merge the aqueous solution after medicinal liquid and distillation, filter, being evaporated to 65 DEG C and surveying relative density is 1.05 Clear paste, standby；
(4) gained clear paste in step (3) is added by volume 15% ethanol, static 12 hours, fling to ethanol, refilter, then It is concentrated into 80 DEG C and surveys the extractum that relative density is 1.15, be placed in -5 DEG C and freeze 48 hours, standby；
(5) raw material acesulfame potassium, sodium benzoate, essence is taken to be respectively crushed into 300 mesh, standby；
(6) gained extractum in step (4) is added pure water, amount of water is 6 times of its weight, in agitator tank, stir 15 points Clock, stands 4 hours, is stirred for 15 minutes, makes serosity flow into 360 mesh sieve hole reciprocating sieves while stirring and filters, obtains filtrate, to filtrate Acesulfame potassium and sodium benzoate after middle addition pulverizing, stirring adds essence after pulverizing after 20 minutes, is stirred for 20 minutes, finally 8 Stand 12 hours under conditions of DEG C, filter, filtrate fill sterilizes, obtain final product the Chinese medicine preparation for the treatment of liver-Yang hyperactivity card.
4. according to claim 1 a kind of treat liver-Yang hyperactivity card Chinese medicine preparation it is characterised in that: by following weight portion Raw material make: 120 parts of Rhizoma Gastrodiae, 300 parts of Ramulus Uncariae Cum Uncis, 300 parts of Semen Ziziphi Spinosae (parched), 200 parts of Radix Polygoni Multiflori Preparata, 200 parts of the Radix Paeoniae Alba, 200 parts of Semen Cassiae, 200 parts of Radix Glehniae, 300 parts of the Radix Astragali, 150 parts of Radix Curcumae, 150 parts of Fructus Lycii, 150 parts of Radix Polygalae, 120 parts of Ganoderma, 60 parts of Radix Glycyrrhizae, Folium Perillae 80 parts of leaf, 120 parts of Pheretima, 120 parts of Cornu Saigae Tataricae, 0.0015 part of acesulfame potassium, 0.0015 part of sodium benzoate, 0.0013 part of essence.
5. according to claim 1 a kind of treat liver-Yang hyperactivity card Chinese medicine preparation it is characterised in that: by following weight portion Raw material make: 150 parts of Rhizoma Gastrodiae, 400 parts of Ramulus Uncariae Cum Uncis, 400 parts of Semen Ziziphi Spinosae (parched), 230 parts of Radix Polygoni Multiflori Preparata, 230 parts of the Radix Paeoniae Alba, 230 parts of Semen Cassiae, 230 parts of Radix Glehniae, 400 parts of the Radix Astragali, 180 parts of Radix Curcumae, 180 parts of Fructus Lycii, 180 parts of Radix Polygalae, 150 parts of Ganoderma, 80 parts of Radix Glycyrrhizae, Folium Perillae 110 parts of leaf, 150 parts of Pheretima, 150 parts of Cornu Saigae Tataricae, 0.002 part of acesulfame potassium, 0.002 part of sodium benzoate, 0.0016 part of essence.
6. according to claim 1 a kind of treat liver-Yang hyperactivity card Chinese medicine preparation it is characterised in that: by following weight portion Raw material make: 90 parts of Rhizoma Gastrodiae, 200 parts of Ramulus Uncariae Cum Uncis, 200 parts of Semen Ziziphi Spinosae (parched), 170 parts of Radix Polygoni Multiflori Preparata, 170 parts of the Radix Paeoniae Alba, 170 parts of Semen Cassiae, 170 parts of Radix Glehniae, 200 parts of the Radix Astragali, 120 parts of Radix Curcumae, 120 parts of Fructus Lycii, 120 parts of Radix Polygalae, 90 parts of Ganoderma, 40 parts of Radix Glycyrrhizae, Folium Perillae 50 parts of leaf, 90 parts of Pheretima, 90 parts of Cornu Saigae Tataricae, 0.001 part of acesulfame potassium, 0.001 part of sodium benzoate, 0.001 part of essence.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461907A (en) * 2009-01-16 2009-06-24 武昌钱治敏西医内科诊所 Medicament for treating liver-yang hyperactivity, extinguishing liver-wind and nourishing kidney-yin as well as preparation method
CN104645080A (en) * 2015-01-29 2015-05-27 崔银方 Traditional Chinese medicine preparation for treating dizziness and preparation method of traditional Chinese medicine preparation
CN104940844A (en) * 2015-07-17 2015-09-30 青岛恒波仪器有限公司 Traditional Chinese medicine preparation for treating liver-fire flaming type palpitation and insomnia and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461907A (en) * 2009-01-16 2009-06-24 武昌钱治敏西医内科诊所 Medicament for treating liver-yang hyperactivity, extinguishing liver-wind and nourishing kidney-yin as well as preparation method
CN104645080A (en) * 2015-01-29 2015-05-27 崔银方 Traditional Chinese medicine preparation for treating dizziness and preparation method of traditional Chinese medicine preparation
CN104940844A (en) * 2015-07-17 2015-09-30 青岛恒波仪器有限公司 Traditional Chinese medicine preparation for treating liver-fire flaming type palpitation and insomnia and preparation method thereof

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Application publication date: 20170201