CN106361937A - 一种多味祛风补肾浓缩剂的制备方法 - Google Patents

一种多味祛风补肾浓缩剂的制备方法 Download PDF

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CN106361937A
CN106361937A CN201610858168.5A CN201610858168A CN106361937A CN 106361937 A CN106361937 A CN 106361937A CN 201610858168 A CN201610858168 A CN 201610858168A CN 106361937 A CN106361937 A CN 106361937A
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霍波
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Abstract

一种多味祛风补肾浓缩剂的制备方法，医技术领域，在于解决腰椎骨质增生的治疗问题，其特征是按下面的制作步骤制作而成：一、所用的制作原料：肉苁蓉、牡蛎3、黑骨藤、牛膝、海藻、桑寄生、山药、金银花、透骨草、柴胡、当归、枸杞子、海风藤、甘草；二、将各中药用清水浸润2~3小时；三、将浸润的各中药与适量清水煎煮20~30分钟；四、将混合药煎液进行分离后得到药液；五、将药液进行静置或离心澄清得到较纯的药液；六、药液的浓缩：将药液进行低温减水蒸馏得到浓缩药液，蒸馏温度30℃~45℃，浓缩药浓度：30~40%；七、将浓缩液再次高温灭菌灭菌温度100℃~105℃、高温灭菌时间60~100秒，降温后装瓶密封即成。

Description

一种多味祛风补肾浓缩剂的制备方法
技术领域
本发明涉及一种治疗腰椎病的药剂及其制备方法，属于医药技术领域。
背景技术
腰椎骨质增生的主要病因与关节软骨的退行性病变有关，腰椎的骨质增生是因为中年以后，腰椎骨质增生随着年龄的增大，机体各组织细胞的生理功能也逐渐衰退老化，退化的椎间盘逐渐失去水份，椎间隙变窄，纤维环松弛向周边膨出，椎体不稳，纤维环在椎体边缘外发生撕裂，导致髓核之突出，将后纵韧带的骨膜顶起，其下面产生新骨，形成骨刺或骨质增生，日常生活中应用骨质骨方世医贴和练习倒走以及合理休息，才能有效治愈骨质增生。
骨质增生的主要病因与关节软骨的退行性病变有关，腰椎的骨质增生是因为中年以后， 随着年龄的增大，机体各组织细胞的生理功能也逐渐衰退老化，退化的椎间盘逐渐失去水份，椎间隙变窄，纤维环松弛向周边膨出，椎体不稳，纤维环在椎体边缘外发生撕裂，导致髓核之突出，将后纵韧带的骨膜顶起，其下面产生新骨，形成骨刺或骨质增生。也有人认为椎间盘退变萎缩后，椎体向前倾斜，椎体前缘在中线为前纵韧带所阻，两侧骨膜掀起，骨膜下形成新骨。另外，局部的受压因素也是引起腰椎骨质增生的主要因素，腰椎椎体边缘受压较重，故此处骨质增生的发生也较常见。
骨质增生在临床上常出现腰椎及腰部软组织酸痛、胀痛、僵硬与疲乏感，甚至弯腰受限。如邻近的神经根受压，可引起相应的症状，出现局部疼痛、发僵、后根神经痛、麻木等。如压迫坐骨神经可引起坐骨神经炎，出现患肢剧烈麻痛、灼痛、抽痛、串痛、向整个下肢放射。
腰椎骨质增生一般主要与年龄、劳损、外伤、姿势不正确等有着直接的关系。
(一) 年龄因素：人体的老化是不可抗拒的自然规律，随着年龄的增长，腰椎由于运动磨损不可避免地会出现退行性改变，绝大部分60岁以上的正常人拍片时均可发现腰椎的骨刺形成，椎间隙狭窄等退变老化现象。
(二)劳损因素： 腰椎的退变过程，除随年龄变化以外，还与腰椎劳损有很大关系，腰椎长期受到反复劳损以及过度活动等不良因素的刺激，则有可能加速腰椎的退变，使椎间盘突出，骨刺的形成并不断增大；反之，注意腰部的休息和保养，就可以减缓腰椎的退变速度和骨刺的进展。
(三）外伤史：青少年时代的腰椎外伤，也是中年以后发生腰椎骨质增生的重要外因。
(四)姿势不正确：腰椎骨质增生症年轻患者主要是与长时间维持同一个姿势，同时姿势不正确导致睡软的席梦思床垫，长时间睡姿不正确也会导致腰椎骨质增生。
腰椎骨质增生的治疗主要以中医中药论治。传统黑膏药腰痛复正贴作为传统黑膏药的典型代表，由川乌、草乌、细辛、杜仲、一枝蒿、乳香、没药、大黄、血竭、樟脑、冰片、老蒜、葱白、生姜等多味名贵中药经古法熬制而成，是遵循中药归经原则，运用药物互相协调为用的效能，组成的多味药物大组方，以发挥药材的良好功效。由于膏药用于肌表薄贴，所以中取芳香透达之药物，并加以引药率领群药，开结行滞直达病所。因此可透入皮肤产生活血，止痛，化淤，通经走络，开窍透骨，祛风散寒等效果，并通过药物的归经作用而调理机体阴阳平衡，扶正固本、改善体质。
发明内容
为了能正解有效地治疗腰椎骨质增生，必须能正解诊断腰椎骨质增生的病根原因，其实腰椎骨质增生的根本原因不在于劳累和坐姿势不正，以中医学分析腰椎骨质增生，属于肾精亏损，风寒湿邪、侵入骨髓，首生肾虚致腰椎间肌肉收缩力下降，致腰间骨质逐渐增生，甚至有的发展成为弓腰；另一方面肾虚致免疫力低下，风趁虚而入，风邪病毒蕴结，产发生腰病。由此分析，我们治疗腰椎骨质增生，应以补肾装腰、祛风排毒、活血通络之中药组合治疗，并把组合药物提取制作成中成药，利于服用。
一种多味祛风补肾浓缩剂的制备方法解决问题所采取的技术方案是按下面的制作步骤制作而成：一、所用的制作原料质量份比：肉苁蓉15份、牡蛎30份、黑骨藤10份、牛膝15份、海藻15份、桑寄生15份、山药20份、金银花15份 、透骨草10份、柴胡15份、当归12份、枸杞子12份、海风藤10份、甘草8份；二、将各中药用清水浸润2~3小时；三、将浸润的各中药与适量清水煎煮20~30分钟成为混合药煎液；四、将混合药煎液进行分离后得到药液；五、将药液进行静置或离心澄清得到较纯的药液；六、药液的浓缩：将药液进行低温减水蒸馏得到浓缩药液，蒸馏温度30℃~45℃，浓缩药浓度：30~40%；七、将浓缩液再次高温灭菌灭菌温度100℃~105℃、高温灭菌时间60~100秒，降温后装瓶密封即成。
下面对一种多味祛风补肾浓缩剂的制备方法中的各中药成份药性功效作分析。肉苁蓉功能主治：补肾阳，益精血，润肠通便。用于阳痿，不孕，腰膝酸软，筋骨无力，肠燥便秘.指导意见：应用1.用于肾虚阳痿，遗精早泄及腰膝冷痛，筋骨痉弱.治肾虚阳。牡蛎的功效：敛阴，潜阳，止汗，涩精，化痰，软坚；治惊痫，眩晕，自汗，盗汗，遗精，淋浊，崩漏，带下，瘰疬，瘿瘤；用于惊悸失眠，眩晕耳鸣，瘰疠痰核，瘕痞块，自汗盗汗、牙齿酸痛。黑骨藤功效: 通经络、去风湿、活血、消炎； 能祛风除湿, 通络止痛；用于风寒湿痹, 臂痛, 腰痛, 腿疼痛等疾。牛膝散瘀血，消痈肿、补肝肾，强筋骨，治腰膝骨痛。 海藻功效：软坚, 消痰,利水, 泄热；治瘰疬, 瘿瘤, 积聚, 水肿, 睾丸肿痛。桑寄生归肝、肾经；用于补肝肾；强筋骨；祛风湿；安胎；主腰膝酸痛；筋骨痿弱；肢体偏枯；风湿痹痛；头错目眩；胎动不安，崩漏下血。生姜能增强和加速血液循环，刺激胃液分泌，帮助消化，有健胃的功能。淮山药的功效与作用是补脾、养肺、固肾、益精、治脾虚泄泻、遗精、带下、肾虚尿频、食少浮肿、肺虚咳喘、消渴。枸杞子能补肾益精，养肝明目，补血安神，生津止渴，润肺止咳。金银花既能宣散风热，还善清解血毒，用于各种热性病，如身热、发疹、发斑、热毒疮痈、咽喉肿痛等证，均效果显著。 金银花的功效概述：清热解毒，凉散风热。透骨草有祛风胜湿、活血止痛；舒筋活络, 祛风胜湿,活血止痛,软坚消痞。柴胡功效：和表解里, 疏肝, 升阳；用于:感冒发热, 寒热往来, 胸胁胀痛, 月经不调, 宫脱垂, 脱肛。当归补血和血，调经止痛，润燥滑肠，用于血虚，面色萎黄，眩晕心悸；血虚，或兼有瘀滞的月经不调、经闭、痛经，虚寒性腹痛、冠心病心绞痛、风湿痹痛。当归健脾，补肺，固肾，益精，治脾虚泄泻，久痢，虚劳咳嗽，消渴，遗精、带下，小便频数，补脾养胃，生津益肺，补肾涩精。海风藤为祛风湿, 通经络的要药, 用于风湿痹证显效。甘草补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。
一种多味祛风补肾浓缩剂的制备方法发明的有益效果是：通过以中医学正解分析腰椎骨质增生，属于肾精亏损，风寒湿邪、侵入骨髓，肾虚致腰椎间肌肉收缩力下降，致腰间骨质逐渐增生；另一方面肾虚致免疫力低下，风趁虚而入，风邪病毒蕴结，产发生腰病；采取以补肾装腰、祛风排毒、活血通络之中药组合，并把各组合药物提取制作成中成药剂，利于服用，医学理论分析正解，应用治疗效果显著。
具体实施方式
下面以瓶装的一种多味祛风补肾浓缩剂药剂量作为优选实施例对一种多味祛风补肾浓缩剂的制备方法进一步的说明。
一种多味祛风补肾浓缩剂的制备方法制作一瓶装的药量是按下面的中药量及制作步骤：一、所用的制作原料质量份比：肉苁蓉15克、牡蛎30克、黑骨藤10克、牛膝15克、海藻15克、桑寄生15克、山药20克、金银花15克 、透骨草10克、柴胡15克、当归12克、枸杞子12克、海风藤10克、甘草8克；二、将各中药用清水浸润2~3小时；三、将浸润的各中药与适量清水煎煮20~30分钟成为混合药煎液；四、将混合药煎液进行分离后得到药液；五、将药液进行静置或离心澄清得到较纯的药液；六、药液的浓缩：将药液进行低温减水蒸馏得到浓缩药液，蒸馏温度30℃~45℃，浓缩药浓度：30~40%；七、将浓缩液再次高温灭菌灭菌温度100℃~105℃、高温灭菌时间60~100秒，降温后装瓶密封即成。
一种多味祛风补肾浓缩剂使用方法：重症患者日服一瓶，连服一个星期为一个疗程，服用一瓶即可得到改良效果、腰酸痛感消失，一个星期后可减量连续服用1个月。一种多味祛风补肾浓缩剂属于功能性中成药剂，适合于肾虚亏损者，治疗改良有效率100%，治愈率95%，疗效稳定，使用安全。

Claims (1)

1.一种多味祛风补肾浓缩剂的制备方法，其特征是按下面的制作步骤制作而成：一、所用的制作原料质量份比：肉苁蓉15份、牡蛎30份、黑骨藤10份、牛膝15份、海藻15份、桑寄生15份、山药20份、金银花15份 、透骨草10份、柴胡15份、当归12份、枸杞子12份、海风藤10份、甘草8份；二、将各中药用清水浸润2~3小时；三、将浸润的各中药与适量清水煎煮20~30分钟成为混合药煎液；四、将混合药煎液进行分离后得到药液；五、将药液进行静置或离心澄清得到较纯的药液；六、药液的浓缩：将药液进行低温减水蒸馏得到浓缩药液，蒸馏温度30℃~45℃，浓缩药浓度：30~40%；七、将浓缩液再次高温灭菌灭菌温度100℃~105℃、高温灭菌时间60~100秒，降温后装瓶密封即成。
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