CN106360734A - Composition with both roles of weight losing and facial features beautifying and preparing method and application thereof - Google Patents
Composition with both roles of weight losing and facial features beautifying and preparing method and application thereof Download PDFInfo
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- CN106360734A CN106360734A CN201610858795.9A CN201610858795A CN106360734A CN 106360734 A CN106360734 A CN 106360734A CN 201610858795 A CN201610858795 A CN 201610858795A CN 106360734 A CN106360734 A CN 106360734A
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- arabinose
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention belongs to the field of drugs, health care products or food, and particularly relates to a composition with both roles of weight losing and facial features beautifying and a preparing method and an application thereof. The composition is prepared from, by weight, 3-15 parts of L-threonic acid magnesium, 6-20 parts of arabinose, 0.5-8 parts of lemon extractive, 1-15 parts of collagen peptide, 1-9 parts of grapefruit extractive and 0.1-5 parts of guarana extractive. The composition with both roles of weight losing and facial features beautifying takes a full consideration of the compositions of the raw materials and chooses the ratios among the raw materials, thus making the raw materials coordinate with each other and play the roles together according to the ratios; in addition, the composition not only plays the role of weight losing, but also can improve the luster and the elasticity of the skin at the time of weight losing so that the skin will not lose elasticity and generate collapse because of fat reducing, thus playing the role of facial features beautifying at the same time.
Description
Technical field
The invention belongs to medicine, health product or field of food are and in particular to a kind of have fat-reducing and beautification function simultaneously
Compositionss and preparation method thereof and purposes.
Background technology
With expanding economy, the living standard of people improves constantly, and overnutrition and food rich in fat picked-up make part
Obesity in crowd, and the incidence rate of obesity is in ascendant trend year by year.
Obesity is defined as a kind of disease by World Health Organization (WHO), rather than simple overweight.Obesity is internal
A kind of state that fat, especially triglyceride accumulation are excessive and lead to, is a kind of multifactor chronic metabolic diseases causing.Fertile
Fat, not only bring the worry of itself figure, more grave danger is caused to human health.Research finds, fat and coronary disease
The diseases such as disease, apoplexy, cerebral thrombosiss, hypertension, hyperlipidemia, hyperglycemia are closely related, jeopardize health of human body.
The medicine of existing fat-reducing or health product are achieved the goal by the method for diarrhoea mostly, or even some also added fiber crops
The violated product such as flavin, not only may produce harmful effect to health after taking, and be likely to be of larger side effect.This
Outward, after fat-reducing, by the fatty minimizing of body institute, skin often follows the string, glossiness reduces, it is lax to occur, and skin wrinkles
Stricture of vagina also progressively increases.
Chinese patent literature cn104287049a discloses a kind of generation meal protein powder solid beverage of Weight management: includes
Following components in percentage by weight: soybean protein isolate 3-5%, skimmed milk powder 35-43%, concentrated whey protein powder 20-25%,
Resistant dextrin 8-10%, alkalize cocoa powder 2-4%, l- carnitine 1.0-2.0%, Paullina Cupana extract 0.5-0.8%, soybean dietary
Fiber powder 0.5-0.8%, pea fibre 0.1-0.3%, Herba avenae fatuae fiber 0.1-0.3%, erythritol 4-8%, steviol glycosides
0.1-0.2%, phosphatidase 1-1.5%, arabic gum 3-5%, xanthan gum 0.1-0.3%, pectin 0.1-0.3%, edible essence 2-
3%.However, above-mentioned composition only has antiobesity action, the led to skin of can not solving to lose weight follows the string, glossiness
Reduce, lax, the problem that wrinkle of skin increases occurs, thus limiting its application.
Therefore, the new therapeutic effect of research is good, toxic and side effects are little, raw material composition simple, lower-cost both had subtract
The fertile medicine acting on and having beautification function or health product are significant.
Content of the invention
Therefore, the present invention provide a kind of therapeutic effect good, toxic and side effects are little, lower-cost not only there is antiobesity action but also
There are the compositionss of beautification function, and then its preparation method and purposes are provided.
For solving above-mentioned technical problem, the present invention is achieved through the following technical solutions:
Present invention offer is a kind of not only to have been had antiobesity action but also had had the compositionss of beautification function, the raw material of described compositionss
Including:
L- magnesium threonate 3～15 weight portion, arabinose 6～20 weight portion, citron extract 0.5～8 weight portion, collagen
Protein peptide 1～15 weight portion, Citrua paradiai extract 1～9 weight portion, Paullina Cupana extract 0.1～5 weight portion.
Preferably, the present invention is above-mentioned had not only had antiobesity action but also had had the compositionss of beautification function, described compositionss former
Material includes:
L- magnesium threonate 5～13 weight portion, arabinose 9～17 weight portion, citron extract 2～6 weight portion, collagen egg
White peptide 4～12 weight portion, Citrua paradiai extract 3～7 weight portion, Paullina Cupana extract 1～3 weight portion.
It is further preferred that the present invention was above-mentioned and not only having there is antiobesity action but also there are the compositionss of beautification function, described combination
The raw material of thing includes:
L- magnesium threonate 9 weight portion, arabinose 13 weight portion, citron extract 4 weight portion, collagen peptide 8 weight
Part, Citrua paradiai extract 5 weight portion, Paullina Cupana extract 2 weight portion；Or
L- magnesium threonate 5 weight portion, arabinose 17 weight portion, citron extract 2 weight portion, collagen peptide 12 weight
Part, Citrua paradiai extract 3 weight portion, Paullina Cupana extract 3 weight portion；Or
L- magnesium threonate 13 weight portion, arabinose 9 weight portion, citron extract 6 weight portion, collagen peptide 4 weight
Part, Citrua paradiai extract 7 weight portion, Paullina Cupana extract 1 weight portion；Or
L- magnesium threonate 7 weight portion, arabinose 10 weight portion, citron extract 3 weight portion, collagen peptide 11 weight
Part, Citrua paradiai extract 6 weight portion, Paullina Cupana extract 2.5 weight portion.
It is further preferred that the present invention was above-mentioned and not only having there is antiobesity action but also there are the compositionss of beautification function, described combination
The raw material of thing also includes: local flavor regulator 0.1-3 weight portion,
Described local flavor regulator is selected from citric acid, malic acid, sodium citrate, sucralose, Fructose, acesulfame potassium, stevioside
At least one in glycosides, sucrose, aspartame.
The present invention also provides a kind of above-mentioned preparation method not only having had antiobesity action but also having had the compositionss of beautification function,
Comprise the following steps:
The l- magnesium threonate of selected weight portion, arabinose, citron extract, collagen peptide, Citrua paradiai is taken to extract respectively
Thing and Paullina Cupana extract, grinding, mix homogeneously, obtain final product.
The present invention also provides a kind of above-mentioned preparation method not only having had antiobesity action but also having had the compositionss of beautification function,
Comprise the following steps:
The l- magnesium threonate of selected weight portion, arabinose, citron extract, collagen peptide, Citrua paradiai is taken to extract respectively
Thing, Paullina Cupana extract and local flavor regulator, grinding, mix homogeneously, obtain final product.
The present invention also provide including above-mentioned not only there is antiobesity action but also have the compositionss of beautification function preparation or
The preparation of the compositionss preparing including above-mentioned preparation method,
Described compositionss add customary adjuvant, according to common process, make clinically acceptable tablet, capsule, dissipate
Agent, mixture, pill, granule, solution, syrup, soft extract, beverage, cookiess, confection or cake.
Described customary adjuvant is: filler, disintegrating agent, lubricant, suspending agent, binding agent, sweeting agent, correctivess, anti-corrosion
Agent, substrate etc..Filler includes: starch, Pregelatinized Starch, Lactose, Mannitol, chitin, Microcrystalline Cellulose, sucrose etc.；Collapse
Solution agent includes: starch, Pregelatinized Starch, Microcrystalline Cellulose, carboxymethyl starch sodium, crospolyvinylpyrrolidone, low replacement hydroxyl
Third cellulose, cross-linked carboxymethyl cellulose are received；Lubricant includes: magnesium stearate, sodium lauryl sulphate, Pulvis Talci, dioxy
SiClx etc.；Suspending agent includes: Polyvinylpyrrolidone, Microcrystalline Cellulose, sucrose, agar, hydroxypropyl methyl cellulose etc.；Bonding
Agent includes, starch slurry, Polyvinylpyrrolidone, hydroxypropyl methyl cellulose etc.；Sweeting agent includes: saccharin sodium, Aspartane, sugarcane
Sugar, cyclamate, enoxolone etc.；Correctivess include: sweeting agent and various essence；Preservative includes: parabenses, benzoic acid,
Sodium benzoate, sorbic acid and its esters, benzalkonium bromide, the fixed, eucalyptus oil of acetic acid chloroethene etc.；Substrate includes: peg6000,
Peg4000, insect wax etc..
The present invention also provides above-mentioned composition, above-mentioned preparation method prepares compositionss or the system of above-mentioned composition
Application in medicine, health product or the food that preparation has fat-reducing and/or beautification function for the agent.
Technical scheme has the advantage that
(1) compositionss of the present invention, take into full account the composition of each raw material, and select each raw material proportioning each other, make
Each raw material cooperates according to its proportioning, collective effect, and it not only has antiobesity action, and can change while fat-reducing
Kind skin gloss, elasticity, make skin will not follow the string because of fat reducing, produce and subside, thus play beautification function simultaneously；
(2) compositionss of the present invention, composition is simple, cost is relatively low；
(3) by grinding, mix homogeneously can be prepared by compositionss of the present invention, and preparation method is easier.
Specific embodiment
In following examples of the present invention and experimental example, all raw materials are commercially available product.
Embodiment 1
The present embodiment had not only had antiobesity action but also had had the raw material of the compositionss of beautification function and consisted of: l- magnesium threonate
9g, arabinose 13g, citron extract 4g, collagen peptide 8g, Citrua paradiai extract 5g, Paullina Cupana extract 2g；
The preparation method of said composition, comprises the following steps: take respectively the l- magnesium threonate of selected weight, arabinose,
Citron extract, collagen peptide, Citrua paradiai extract and Paullina Cupana extract, grinding, mix homogeneously, obtain final product.
The present embodiment had not only had antiobesity action but also had had the compositionss addition customary adjuvant of beautification function, according to conventional work
Skill, makes granule.
Embodiment 2
The present embodiment had not only had antiobesity action but also had had the raw material of the compositionss of beautification function and consisted of: l- magnesium threonate
5g, arabinose 17g, citron extract 2g, collagen peptide 12g, Citrua paradiai extract 3g, Paullina Cupana extract 3g, citric acid
0.1g；
The preparation method of said composition, comprises the following steps: take respectively the l- magnesium threonate of selected weight, arabinose,
Citron extract, collagen peptide, Citrua paradiai extract, Paullina Cupana extract and citric acid, grinding, mix homogeneously, obtain final product.
The present embodiment had not only had antiobesity action but also had had the compositionss addition customary adjuvant of beautification function, according to conventional work
Skill, makes capsule.
Embodiment 3
The present embodiment had not only had antiobesity action but also had had the raw material of the compositionss of beautification function and consisted of: l- magnesium threonate
13g, arabinose 9g, citron extract 6g, collagen peptide 4g, Citrua paradiai extract 7g, Paullina Cupana extract 1g, aspartame
3g；
The preparation method of said composition, comprises the following steps: take respectively the l- magnesium threonate of selected weight, arabinose,
Citron extract, collagen peptide, Citrua paradiai extract, Paullina Cupana extract and aspartame, grinding, mix homogeneously, obtain final product.
The present embodiment had not only had antiobesity action but also had had the compositionss addition customary adjuvant of beautification function, according to conventional work
Skill, makes tablet.
Embodiment 4
The present embodiment had not only had antiobesity action but also had had the raw material of the compositionss of beautification function and consisted of: l- magnesium threonate
7g, arabinose 10g, citron extract 3g, collagen peptide 11g, Citrua paradiai extract 6g, Paullina Cupana extract 2.5g, Flos Chrysanthemi
Glucosides 1.5g；
The preparation method of said composition, comprises the following steps: take respectively the l- magnesium threonate of selected weight, arabinose,
Citron extract, collagen peptide, Citrua paradiai extract, Paullina Cupana extract and stevioside, grinding, mix homogeneously, obtain final product.
The present embodiment had not only had antiobesity action but also had had the compositionss addition customary adjuvant of beautification function, according to conventional work
Skill, makes syrup.
Experimental example
Experimental example 1Present composition fat-reducing and the research of beautification function
1st, experiment purpose
Research present composition fat-reducing and the effect of beauty treatment.
2nd, experiment material
With the compositionss of embodiment 1 preparation as test sample.
3rd, experimental technique
3.1 experiment packet
Choose 60 ages 20-40 year healthy women as experimenter, be randomly divided into 2 groups, every group of 30 people, respectively
Experimental group and blank control group.
The compositionss of experimental group oral embodiment 1 preparation 30g/ time, 3 times a day；Blank control group oral placebo 30g/
Secondary, 3 times a day；Continue 90.
During experiment, experimental group box matched group is all normally taken food, and food do not eaten by not snack, does not take any relevant medicine
Product and other health product, and the 30min that jogs daily.
Before testing and after oral 90 days, the body weight of record each group, waistline, hip circumference and cutaneous sense evaluation etc. respectively.
4th, experimental result
The specific experiment result of each group is as shown in table 1.
The specific experiment result of table 1 each group
As shown in Table 1, compared with blank control group, experimental group has significant fat-reducing effect.
Wherein, the weight average of experimental group reduces 1.3kg, and hip circumference averagely reduces 1.5cm, and waistline averagely reduces 2cm；Reduce
Relative percentage is respectively 2.7%, 2.1%, 3.8%.
Additionally, in cutaneous sense evaluation test, in experimental group, the skin of 21 people keeps smooth exquisiteness, ruddy glossy,
Buckling phenomena no occurs；The facial speckle of 6 people there has also been different degrees of mitigation；That is: beauty treatment effective percentage reaches 90%.
From experimental example 1, the compositionss of the embodiment of the present invention 1 preparation, not only there is antiobesity action, and can subtract
While fertile, improve skin gloss, elasticity, so that skin will not be followed the string because of fat reducing, produce and subside, thus play simultaneously
Beautification function.
Obviously, above-described embodiment is only intended to clearly illustrate example, and the not restriction to embodiment.Right
For those of ordinary skill in the art, can also make on the basis of the above description other multi-forms change or
Change.There is no need to be exhaustive to all of embodiment.And the obvious change thus extended out or
Change among still in the protection domain of the invention.
Claims (8)
1. a kind of compositionss are it is characterised in that the raw material of described compositionss includes:
L- magnesium threonate 3～15 weight portion, arabinose 6～20 weight portion, citron extract 0.5～8 weight portion, collagen protein
Peptide 1～15 weight portion, Citrua paradiai extract 1～9 weight portion, Paullina Cupana extract 0.1～5 weight portion.
2. compositionss according to claim 1 are it is characterised in that the raw material of described compositionss includes:
L- magnesium threonate 5～13 weight portion, arabinose 9～17 weight portion, citron extract 2～6 weight portion, collagen peptide
4～12 weight portions, Citrua paradiai extract 3～7 weight portion, Paullina Cupana extract 1～3 weight portion.
3. compositionss according to claim 2 are it is characterised in that the raw material of described compositionss includes:
L- magnesium threonate 9 weight portion, arabinose 13 weight portion, citron extract 4 weight portion, collagen peptide 8 weight portion, west
Fructus Citri grandiss extract 5 weight portion, Paullina Cupana extract 2 weight portion；Or
L- magnesium threonate 5 weight portion, arabinose 17 weight portion, citron extract 2 weight portion, collagen peptide 12 weight portion,
Citrua paradiai extract 3 weight portion, Paullina Cupana extract 3 weight portion；Or
L- magnesium threonate 13 weight portion, arabinose 9 weight portion, citron extract 6 weight portion, collagen peptide 4 weight portion, west
Fructus Citri grandiss extract 7 weight portion, Paullina Cupana extract 1 weight portion；Or
L- magnesium threonate 7 weight portion, arabinose 10 weight portion, citron extract 3 weight portion, collagen peptide 11 weight portion,
Citrua paradiai extract 6 weight portion, Paullina Cupana extract 2.5 weight portion.
4. the compositionss according to any one of claim 1-3 are it is characterised in that the raw material of described compositionss also includes: wind
Taste regulator 0.1-3 weight portion,
Described local flavor regulator is selected from citric acid, malic acid, sodium citrate, sucralose, Fructose, acesulfame potassium, stevioside, sugarcane
At least one in sugar, aspartame.
5. a kind of preparation method of the compositionss described in any one of claim 1-3 is it is characterised in that comprise the following steps:
Take respectively the l- magnesium threonate of selected weight portion, arabinose, citron extract, collagen peptide, Citrua paradiai extract and
Paullina Cupana extract, grinding, mix homogeneously, obtain final product.
6. a kind of preparation method of the compositionss described in claim 4 is it is characterised in that comprise the following steps:
Take the l- magnesium threonate of selected weight portion, arabinose, citron extract, collagen peptide, Citrua paradiai extract, melon respectively
Rana extract and local flavor regulator, grinding, mix homogeneously, obtain final product.
7. include the preparation of compositionss described in any one of claim 1-4 or include the preparation described in claim 5 or 6
The preparation of the compositionss that method prepares it is characterised in that
Described compositionss add customary adjuvant, according to common process, make clinically acceptable tablet, capsule, powder, conjunction
Agent, pill, granule, solution, syrup, soft extract, beverage, cookiess, confection or cake.
8. the combination that the compositionss described in any one of claim 1-4, the preparation method described in claim 5 or 6 prepare
The preparation of the compositionss described in thing or claim 7 has medicine, health product or the food of fat-reducing and/or beautification function in preparation
Application in product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610858795.9A CN106360734A (en) | 2016-09-28 | 2016-09-28 | Composition with both roles of weight losing and facial features beautifying and preparing method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610858795.9A CN106360734A (en) | 2016-09-28 | 2016-09-28 | Composition with both roles of weight losing and facial features beautifying and preparing method and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110574893A (en) * | 2018-06-11 | 2019-12-17 | 江苏帝尔生物科技有限公司 | nutritional meal replacement product with effects of maintaining beauty and keeping young and preparation method thereof |
| JP2021522344A (en) * | 2018-04-25 | 2021-08-30 | ニュロセントリア インコーポレイテッドＮｅｕｒｏｃｅｎｔｒｉａ， Ｉｎｃ． | Magnesium threonic acid composition and its use |
| CN115868628A (en) * | 2022-10-11 | 2023-03-31 | 泓博元生命科技（深圳）有限公司 | Weight-reducing composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104961636A (en) * | 2015-07-14 | 2015-10-07 | 启东东岳药业有限公司 | Synthesis method of magnesium L-threonate |
| CN105725191A (en) * | 2016-02-16 | 2016-07-06 | 江苏隆力奇生物科技股份有限公司 | Composition having face-beautifying and weight-losing effects and preparation method and application thereof |
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2016
- 2016-09-28 CN CN201610858795.9A patent/CN106360734A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104961636A (en) * | 2015-07-14 | 2015-10-07 | 启东东岳药业有限公司 | Synthesis method of magnesium L-threonate |
| CN105725191A (en) * | 2016-02-16 | 2016-07-06 | 江苏隆力奇生物科技股份有限公司 | Composition having face-beautifying and weight-losing effects and preparation method and application thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021522344A (en) * | 2018-04-25 | 2021-08-30 | ニュロセントリア インコーポレイテッドＮｅｕｒｏｃｅｎｔｒｉａ， Ｉｎｃ． | Magnesium threonic acid composition and its use |
| US11717501B2 (en) | 2018-04-25 | 2023-08-08 | Neurocentria, Inc. | Magnesium threonate compositions and uses thereof |
| CN110574893A (en) * | 2018-06-11 | 2019-12-17 | 江苏帝尔生物科技有限公司 | nutritional meal replacement product with effects of maintaining beauty and keeping young and preparation method thereof |
| CN115868628A (en) * | 2022-10-11 | 2023-03-31 | 泓博元生命科技（深圳）有限公司 | Weight-reducing composition |
| CN115868628B (en) * | 2022-10-11 | 2024-01-26 | 泓博元生命科技（深圳）有限公司 | Weight-reducing composition |
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Application publication date: 20170201 |