CN106344944A - Pulse sterilizing equipment - Google Patents

Pulse sterilizing equipment Download PDF

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Publication number
CN106344944A
CN106344944A CN201610776392.XA CN201610776392A CN106344944A CN 106344944 A CN106344944 A CN 106344944A CN 201610776392 A CN201610776392 A CN 201610776392A CN 106344944 A CN106344944 A CN 106344944A
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CN
China
Prior art keywords
sterilizing
vacuum
casing
pulsated
cavity
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Granted
Application number
CN201610776392.XA
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Chinese (zh)
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CN106344944B (en
Inventor
刘万忠
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HUBEI HOPE PHARMACEUTICAL CO Ltd
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HUBEI HOPE PHARMACEUTICAL CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24Apparatus using programmed or automatic operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10Apparatus features
    • A61L2202/13Biocide decomposition means, e.g. catalysts, sorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/24Medical instruments, e.g. endoscopes, catheters, sharps

Abstract

The application of the invention discloses pulse sterilizing equipment which comprises a liquid storage system, a separating and drying system, a detecting system, a spraying system, a vacuum system, a sterilizing box body and a control system. The air in the sterilizing box body, the liquid storage system and the separating and drying system is pumped into vacuum through the vacuum system, and as the boiling point of a disinfector is reduced under the vacuum condition, and the disinfector is much easier to evaporate, the atomizing effect and the drying efficiency of the disinfector are greatly improved, an atomized particle is smaller, even reaches a nanometer scale, is much closer to bacteria in size, can suspend in the air for a long period of time, and is in full contact with the bacteria in the air to fulfill the purpose of sterilizing, in addition, the pulse sterilizing equipment is reasonable in design, simple in structure, convenient in operation and lower in cost, not only is a small sealable sterilizing box body sterilized, but also various small pipelines and small containers, which are hard to sterilize, in the sterilizing box body can be sterilized.

Description

A kind of Pulsated sterilizing equipment
Technical field
The present invention relates to disinfecting field, particularly to a kind of Pulsated sterilizing equipment.
Background technology
It is known that most of plastics non-refractory and corrosion, the various pipelines being made up of these plastic materials and packaging Container equally also non-refractory and corrosion.When these plastic materials be used as food and pharmaceutical packing material (as eye-drop liquid bottle) with And it is necessary to sterilize to it during medical apparatus and instruments (as various endoscopies, disposable syringe etc.).
At present for the cavity of various non-refractories, plastic conduit and plastic containers (as plastic catheter, disposable syringe With plastic bottle etc.) sterilizing methods have epoxyethane method, flowing steam method, chemical disinfection liquid ablution, ultraviolet irradiation, smelly Oxygen sterilization and vaporized hydrogen peroxide (vhp) sterilization etc..These methods cut both ways: ethylene oxide sterilizing effect the most may be used Lean on, but oxirane is strong with the affinity of plastics, residual is difficult to clean off, and higher to equipment requirements, to environment toxic action Also larger;Chemical disinfection liquid ablution troublesome poeration, need to clean one by one it is difficult to reach the effect of complete sterilizing;Ultraviolet irradiates Method effect is very limited, and ultraviolet is easily blocked by object and affects and form lighting dead angle, thus Disinfection Effect it is not believed that.Stream Logical steaming process sterilizing results contrast satisfaction, but if the temperature and pressure control of steam is improper, easily makes plastic material be deformed. Ozonization reliable results, easy and simple to handle, but ozone has very strong oxidisability, in addition to gold and platinum, almost to all its Its metal has corrosiveness, particularly aluminum, zinc, lead can be aoxidized strongly, also have strong corrosiveness to nonmetallic materials, Even if other places highly stable material such as igelite be used and the rubber as encapsulant be also easy to by Ozone oxidation;Although vaporized hydrogen peroxide sterilization can reach sterilization effect, because the hydrogen peroxide of high concentration to be used is (big In 30%), not only using abnormally dangerous, corrosivity are very strong, and device therefor is also very expensive.Therefore, lack one kind suitable Sterilizing installation carry out disinfection sterilizing.
Content of the invention
In order to solve the problems, such as a kind of prior art suitable sterilizing installation of shortage, embodiments provide a kind of arteries and veins Dynamic sterilizing installation.Described technical scheme is as follows:
A kind of Pulsated sterilizing equipment, described Pulsated sterilizing equipment includes: liquid-storage system, separate drying system, detecting system, Spraying system, vacuum system, sterilizing casing and control system, the described drying system that separates is located above described liquid-storage system, and The described drying system that separates is connected with described liquid-storage system, and described liquid-storage system is used for depositing disinfectant, and described separation is dried system System is sequentially connected with described sterilizing casing, described spraying system, and described spraying system also separates drying system, described storage with described Liquid system connects respectively, and described sterilizing casing is also connected respectively with described detecting system, described vacuum system, described control system It is all connected with described spraying system, described vacuum system, described detecting system.
Preferably, described liquid-storage system includes reservoir, tube for transfusion, in described reservoir, deposit disinfectant, described storage Liquid device top is connected with the described drying system that separates, and described reservoir bottom is provided with outage, described tube for transfusion one end and institute State outage to connect, the described tube for transfusion other end is connected with described spraying system.
Preferably, described spraying system includes blower fan, Venturi tube, fog-spray nozzle, described sterilizing casing and described blower fan, Described Venturi tube, described fog-spray nozzle, the described drying system that separates are sequentially connected with, and described Venturi tube is also with described tube for transfusion even Connect.
Preferably, described separation includes at least one cavity, described cavity sidepiece and described spraying inside drying system Head connects, and described cavity bottom is connected with described reservoir.
Preferably, described separate the first cavity, the second cavity and the 3rd sky including inside drying system being sequentially connected with Chamber, described first cavity bottom is connected with described reservoir, and described first cavity sidepiece is connected with described fog-spray nozzle, and the described 3rd Cavity is also connected with described sterilizing casing, and described 3rd cavity top is provided with opening, and described opening is provided with closure, institute State the 3rd cavity bottom to be connected with described first cavity or reservoir.
Preferably, described sterilizing casing includes box-like body, support, described box-like body is internally provided with multiple Frame, described support is used for place the object of sterilizing to be sterilized.
Further, described sterilizing casing also includes breathing circuit filter and vacuum meter, and described breathing circuit filter is located at described Outside box-like body, and described breathing circuit filter, described vacuum meter are all connected with described box-like body.
Preferably, described vacuum system includes the vacuum tube of the vacuum pump and resistance to negative pressure being sequentially connected with, described vacuum tube Also it is connected with described box-like body.
Preferably, described detecting system includes sensing device, signal processing apparatus and the display device being sequentially connected with, institute State sensing device to be connected with described box-like body, described sensing device is also connected with spraying system.
Further, described Pulsated sterilizing equipment also includes at least one shell, described liquid-storage system, described separation drying System, described sterilizing casing, described spraying system and described control system are arranged at described enclosure.
Technical scheme provided in an embodiment of the present invention has the benefit that
The present invention can by vacuum system will sterilize casing, liquid-storage system and separate air in drying system extract out formed true Disinfectant is sprayed into little particle by spraying system by sky, injects and carries out in separation drying system separating, formation drying is dried Nanometer mist, reinjects and is sterilized to sterilization tank body, be back in spraying system afterwards and be circulated;Due in vacuum condition The boiling point of lower disinfectant reduces, and disinfectant is easier to volatilize, and therefore drastically increases disinfectant atomizing effect and drying efficiency, Atomization particle is also less, even up to nanoscale, with antibacterial size more closely, suspending in atmosphere therefore, it is possible to long-time, And be fully contacted with the antibacterial of in the air and reach sterilization purpose;And, the present invention is reasonable in design, and structure is simple, easy to operate, Cost is relatively low, and the present invention not only can sterilize to small-sized salable casing, but also can be each to being placed in casing The object planting the more difficult sterilizing such as small pipeline and small containers is sterilized.
Brief description
Fig. 1 is the structural representation of Pulsated sterilizing equipment provided in an embodiment of the present invention;
Wherein: 1 liquid-storage system, 11 reservoirs, 12 outages, 13 tube for transfusions,
2 spraying systems, 21 blower fans, 22 Venturi tubes, 23 fog-spray nozzles,
3 sterilizing casings, 31 box-like body, 32 supports, 33 breathing circuit filters,
4 vacuum systems,
5 shells,
6 separation drying systems, 61 first cavitys, 62 second cavitys, 63 the 3rd cavitys,
7 detecting systems.
Specific embodiment
With reference to embodiment in detail the application is described in detail, but the application is not limited to these embodiments.
As shown in figure 1, embodiments providing a kind of Pulsated sterilizing equipment, described Pulsated sterilizing equipment includes: storage Liquid system 1, separation drying system 6, detecting system 7, spraying system 2, vacuum system 4, sterilizing casing 3 and control system, described Separate drying system 6 to be located above described liquid-storage system 1, and the described drying system 6 that separates is connected with described liquid-storage system 1, institute State liquid-storage system 1 to be used for depositing disinfectant, the described drying system 6 that separates sterilizes casing 3, described spraying system 2 sequentially with described Connect, described spraying system 2 also with described separate drying system 6, described liquid-storage system 1 connects respectively, described sterilizing casing 3 is also It is connected respectively with described detecting system 7, described vacuum system 4, described control system and described spraying system 2, described vacuum system System 4, described detecting system 7 are all connected with.
Wherein, control system typically adopts plc program control system.It is defeated that separation drying system 6 top is provided with nanometer mist Outlet, is connected with the nanometer mist inlet of sterilizing casing 3 by pipeline;Vacuum system 4 passes through pipeline and phase in sterilizing casing 3 Connection, separates drying system 6 and sterilizing casing 3, spraying system 2, separates drying system 6 and be sequentially connected with, form circulation, by true Empty set system 4 will sterilize casing 3, liquid-storage system 1 and separate drying system 6 in air extract out formation vacuum, ultimately forming one can Closed circuit with the sterilizing that carries out disinfection under vacuum;Disinfectant is sprayed into by little particle, injection point by spraying system 2 Carry out separating in drying system 6, the nanometer mist that form drying is dried, reinject and sterilized to sterilizing casing 3, return afterwards It is back in spraying system 2 and be circulated;Boiling point due to disinfectant under vacuum reduces, and disinfectant is easier to volatilize, because This drastically increases disinfectant atomizing effect and drying efficiency, and atomization particle is also less, even up to (0.1 micron of nanoscale Below), with antibacterial size more closely, suspending in atmosphere therefore, it is possible to long-time, and it is fully contacted with the antibacterial of in the air And reach sterilization purpose;And, the present invention is reasonable in design, and structure is simple, and easy to operate, cost is relatively low, and the present invention not only may be used To sterilize to small-sized salable sterilizing casing 3, but also can be to being placed on various small pipelines and little in sterilizing casing 3 The object of the more difficult sterilizing such as type container is sterilized.
As shown in figure 1, preferably, described liquid-storage system 1 includes reservoir 11, tube for transfusion 13, in described reservoir 11 Deposit disinfectant, described reservoir 11 top is connected with the described drying system 6 that separates, described reservoir 11 bottom is provided with discharge opeing Hole 12, described tube for transfusion 13 one end is connected with described outage 12, and described tube for transfusion 13 other end is with described spraying system 2 even Connect.Opening is additionally provided with tube for transfusion 13, is connected with a two-port valve at opening, uses as discharge opeing or liquid feeding.
As shown in figure 1, preferably, described spraying system 2 includes blower fan 21, Venturi tube 22, fog-spray nozzle 23, described go out Bacterium casing 3 is sequentially connected with described blower fan 21, described Venturi tube 22, described fog-spray nozzle 23, the described drying system 6 that separates, institute State Venturi tube 22 to be also connected with described tube for transfusion 13.Wherein, in the presence of blower fan 21, the disinfectant in reservoir 11 is passed through Tube for transfusion 13 road is sucked in spraying system 2 is sprayed.Blower fan 21 is high speed air-heater 21.
As shown in figure 1, preferably, described separate internal at least one cavity of inclusion of drying system 6, described cavity sidepiece It is connected with described fog-spray nozzle 23, described cavity bottom is connected with described reservoir 11.
As shown in figure 1, preferably, described separate internal the first cavity 61, second including being sequentially connected with of drying system 6 Cavity 62, the 3rd cavity 63, described first cavity 61 bottom is connected with described reservoir 11, described first cavity 61 sidepiece and institute State fog-spray nozzle 23 to connect, described 3rd cavity 63 is also connected with described sterilizing casing 3, and described 3rd cavity 63 top is provided with out Mouthful, described opening is provided with closure, described 3rd cavity 63 bottom is connected with described first cavity 61 or reservoir 11.
Wherein, in the embodiment of the present invention, when containing three cavitys, the top of each cavity and bottom are provided with out Hole, passes through pipeline between each cavity or the dividing plate with perforate is attached in series, can between two cavitys Arranged with last 1 cavity it is also possible to be attached otherwise, being connected with sterilizing casing 3 in integral structure Perforate is as the last outlet of nanometer mist;
Last the 3rd cavity 63 setting extends to a nanometer mist delivery outlet by pipeline, and passes through pipeline and two-port valve and go out The nanometer mist inlet of bacterium casing 3 is connected;3rd cavity 63 bottom is also provided with aperture, by pipeline and the first cavity 61 or reservoir 11 be connected, the 3rd cavity 63 top is provided with the opening of closure, and on the first cavity 61 or liquid storage Perforate can also be arranged on device 11, the disinfectant of addition can be made to flow into reservoir with not remaining as the addition mouth of disinfectant In 11;Other perforate disinfectant can also be added on the other cavitys separating drying system 6 or on reservoir 11.
As shown in figure 1, preferably, described sterilizing casing 3 includes box-like body 31, support 32, described box-like body 31 It is internally provided with multiple supports 32, described support 32 is used for place the object of sterilizing to be sterilized.
As shown in figure 1, further, described sterilizing casing 3 also includes breathing circuit filter 33 and vacuum meter, described breathes Filter 33 is located at outside described box-like body 31, and described breathing circuit filter 33 is connected with described box-like body 31, described vacuum Table is connected with described box-like body 31.
As shown in figure 1, preferably, described vacuum system 4 includes the vacuum tube of the vacuum pump and resistance to negative pressure being sequentially connected with, Described vacuum tube is also connected with described box-like body 31.Wherein, vacuum system 4 may also include the parts such as two-port valve, and vacuum pump is Oil pump or water pump, preferably water pump, vacuum pump can independent of outside the shell 5 of the present invention it is also possible to be installed on shell 5 it Interior, it is connected with sterilizing casing 3 with two-port valve (vacuum valve) by vacuum tube.
Preferably, described detecting system 7 includes sensing device, signal processing apparatus and the display device being sequentially connected with, Described sensing device is connected with described box-like body 31.Wherein, using the change that detection nanometer mist disinfectant is special in detecting system 7 Learn sensor and signal amplifier and character display, described chemical sensor mainly includes detecting nanometer mist disinfectant Sensor special, sensor may be mounted in sterilizing casing 3 it is also possible to be arranged on the wind pipe of sterilizing casing 3, also may be used It is connected with the air inlet of spraying system 2 or air outlet.
As shown in figure 1, further, described nanometer mist disinfector also includes at least one shell 5, described liquid storage System 1, described separation drying system 6, described sterilizing casing 3, described spraying system 2 and described control system are arranged at described Inside shell 5.Vacuum system 4 and detecting system 7 can be arranged on described shell 5 inside it is also possible to be arranged on outside described shell 5 Portion.Wherein, described vacuum system 4, spraying system 2, drying system 6, control system, sterilizing casing 3 and detecting system 7 are separated All can be included in a shell 5 etc. all parts, when including multiple shell 5, you can outer to be included in two or three In shell 5, such as spraying system 2 and separation drying system 6 are included in a shell 5, vacuum system 4, sterilizing casing 3, control system System and detecting system 7 etc. are included in another shell 5, outside vacuum system 4 even can also be independent of shell 5.
In the embodiment of the present invention, when specifically carrying out disinfection sterilization processes, carried out using pulse mode: vacuum system 4 is first First the air in sterilizing casing 3, reservoir 11 and separation drying system 6 is extracted out and form vacuum, then starting spraying system 2 will Disinfectant in liquid-storage system 1 is sprayed to less than 10 microns of little particle (wet granular), is injected in separation drying system 6 and carries out Separate, be dried, form dry nanometer mist disinfectant, this nanometer mist disinfectant is passed through to receive in pipeline and sterilizing casing 3 Rice mist inlet is injected in sterilizing casing 3, then is back in spraying system 2 by the nanometer mist outlet in sterilizing casing 3 Row circulation;When the vacuum in the casing 3 that sterilizes reaches normal pressure (vacuum is zero), close spraying system 2, open vacuum system 4, it is evacuated in sterilizing casing 3, restart spraying system 2 and disinfectant is sprayed into little particle, injection separates and system is dried again Carry out in system 6 separating, the nanometer mist that form drying is dried, then be injected in sterilizing casing 3 by pipeline, and by sterilizing casing 3 Middle nanometer mist outlet is back in spraying system 2 and is circulated;By the way of pulsation, produced nanometer mist is sterilized Agent gradation is injected in sterilizing casing 3, includes being injected simultaneously into being placed on various pipelines or the thing such as container sterilizing in casing 3 In vivo.Close the blower fan 21 of spraying system 2 when the vacuum in the casing 3 that sterilizes reaches zero again, sterilizing casing 3 is exposed to and disappears Carry out disinfection in toxic agent nanometer mist sterilizing;
After reaching the predetermined exposure sterilization time, first pass through two-port valve (the sterilizing casing 3 in the embodiment of the present invention On each outlet and porch, control valve all can be flexibly set according to actual needs, typically adopt two-port valve) close sterilization tank Nanometer mist inlet in body 3 and nanometer mist outlet, are then turned on vacuum system 4, are evacuated in sterilizing casing 3, will In sterilizing casing 3, a nanometer mist disinfectant is discharged by way of evacuation, when reaching required vacuum, closes vacuum System 4, opens the breathing circuit filter 33 on sterilizing casing 3, and extraneous fresh air is sucked in sterilizing casing 3;Work as sterilizing When vacuum in casing 3 reaches zero, close the corresponding two-port valve of breathing circuit filter 33, be then turned on vacuum system 4, by sterilization tank In body 3, the nanometer mist disinfectant of residual is discharged;
I.e. nanometer mist disinfectant is injected in sterilizing casing 3 to the thing in sterilizing casing 3 and casing by way of pulsation Body carries out disinfection sterilizing, then using by the way of pulsation by sterilizing casing 3 in the disinfectant that remains discharged by several times, finally make Till in sterilizing casing 3, the disinfectant of the disinfectant of residual and the interior residual of sterilization container drops to below 1ppm.The present invention's Low temperature Pulsated sterilizing equipment not only can carry out disinfection to small-sized salable casing such as freeze dryer sterilizing, but also can be to placement In casing, for example various small pipeline (as various medical speculums) of the object of more difficult sterilizing and small containers (as eye-drop liquid bottle) enter Row sterilization.
In the embodiment of the present invention, actual analysis are carried out using experiment method, sterilizing casing 3 is vacuum tank, with vacuum tank and As a example the eye-drop liquid bottle placed in vacuum tank, the low temperature Pulsated sterilizing equipment measuring the present invention is to eye drip in vacuum tank and vacuum tank The sterilization effect of liquid bottle, concrete grammar is as follows:
1. major experimental material
(bacstearothermophilus spore, spore amount 106cfu/ piece, containing same lot number biological indicator for biological indicator Special culture solution) and tsa, 5%The special sporicide of active hydrogen peroxide.
2. test vacuum drying oven
The length, width and height of vacuum drying oven box house are respectively 1.0m × 0.8m × 1.4m, and volume is 1.12m3.
First according to shown in embodiment accompanying drawing, vacuum drying oven is transformed into low temperature impulse sterilization casing 3 before test: by vacuum 2 apertures are opened at the top of drying baker, respectively as decontaminant concentration detection mouth and nanometer mist inlet, connect and detecting system 7 The two-port valve of connection is connected with nanometer mist inlet two-port valve, will be dense with hydrogen peroxide for the two-port valve connecting with detecting system 7 Degree detector connects, and will be connected with the outlet of spraying system 2 by pipeline with the nanometer mist inlet two-port valve that is connected;Will be true 2 apertures are also opened in the bottom of empty drying baker, respectively as fresh air access port and nanometer mist outlet, connect and breath The two-port valve that the two-port valve that device 33 is connected is connected with blower fan 21 air inlet, the two-way being connected with breathing circuit filter 33 Valve is connected with breathing circuit filter 33, and the two-port valve being connected with blower fan 21 air inlet is passed through pipeline and blower fan 21 air inlet phase Connect;Former casing vacuum outlet is connected with vacuum pump by the two-port valve being connected with vacuum system 4;By this transformation and Connected mode, spraying system 2, separation drying system 6 and sterilizing casing 3 are constituted one and can carry out arteries and veins under vacuum The disinfection system of dynamic circulation.
3. use flow process
(1) pass through funnel and add 5% to disinfectant solution inletThe special sporicide of active hydrogen peroxide is to setting In standby reservoir 11.
(2) on vacuum tank inner support 32, different parts (upper, middle and lower) place 6 biological indicators and subject to sterilization respectively Eye-drop liquid bottle, respectively put into 1 biological indicator at random in 6 eye-drop liquid bottles.
(3) close chamber door and all two-port valves, seal all connecting pipes, open vacuum pump and be connected with vacuum system 4 Logical two-port valve, the vacuum in vacuum tank is evacuated to after -90kpa, closes vacuum pump and this two-port valve.
(4) open the two-port valve that the two-port valve that is connected with nanometer mist inlet is connected with blower fan 21 air inlet, open spray Disinfectant solution is atomized by mist system 2, after continuing atomization 1-5min, closes spraying system after the vacuum in vacuum tank reaches zero System 2 and this two two-port valves.
(5) it is then turned on vacuum pump and the two-port valve being connected with vacuum system 4, the vacuum in vacuum tank is evacuated to -90kpa Afterwards, vacuum pump and this two-port valve are closed.
(6) open the two-port valve that the two-port valve that is connected with nanometer mist inlet is connected with blower fan 21 air inlet again, open Disinfectant solution is atomized by spraying system 2, after continuing atomization 1-5min, closes spraying after the vacuum in vacuum tank reaches zero System 2 and this two two-port valves.
(7) repetitive operation (5) and (6) 1-2 time, open the two-port valve detection wherein hydrogen peroxide connecting with detecting system 7 Sterilizing concentration after turn off this two-port valve.
(8) sealing exposes sterilization 90-120min.
(9) open vacuum pump and two-port valve, the vacuum in sterilizing casing 3 is evacuated to after -90kpa, closes and vacuum system Two-port valves that system 4 is connected, open the two-port valve being connected with breathing circuit filter 33, be connected with breathing circuit filter 33, will be new Fresh air is sucked in sterilizing casing 3, makes vacuum reach the two-port valve that after zero, closing is connected with breathing circuit filter 33.
(10) two-port valve that the two-port valve that keeps being connected with nanometer mist inlet is connected with blower fan 21 air inlet is in pass Closed state, opens the two-port valve being connected with vacuum system 4, opens vacuum pump, the vacuum in vacuum tank is evacuated to again- After 90kpa, close this two-port valve, open the two-port valve being connected with breathing circuit filter 33, be connected with breathing circuit filter 33, will Fresh air is sucked in sterilizing casing 3, makes vacuum close this two-port valve after reaching zero.
(11) repetitive operation (9) and (10) 1-2 time, open the two-port valve connecting with detecting system 7, detect wherein peroxidating The residual concentration of hydrogen turns off this two-port valve to below 1ppm.
(12) press aseptic procedure and take out biological indicator's (spore bar), put into the stearothermophilus spore culture fluid of reference numeral In, according to the operation instructions of purchased biological indicator, it is placed in constant incubator, observe after cultivating 24 hours at 56 ± 1 DEG C. Take simultaneously and make positive control with crowd biological indicator 1.Through the culture of 24 hours, if culture fluid becomes cloudy, color from purple It is changed into yellow and be then judged to the positive;If culture fluid is clarified, color invariant color is then feminine gender;Continue culture to the 7th day, if culture Liquid is changed into yellow, then be judged to sterilize unqualified;If culture fluid is still purple, it is qualified to be judged to sterilize.
4. experimental result
Experimental result is shown in Table 1.As shown in Table 1, when the concentration of active Hydrogen Peroxide Disinfection Solution is 6%, number of times of pulsing For 3 times, seal time is 90 minutes, you can the eye-drop liquid bottle in vacuum tank and case is sterilized and (makes spore decline six right Number), and the residual of disinfectant is less than 1ppm, reaches safety range.
Eye-drop liquid bottle sterile biological indicator testing result in table 1. vacuum tank and case
To sum up, the present invention has the advantage that
1., because the boiling point of solution under vacuum reduces, disinfectant is easier to volatilize, therefore right under vacuum Disinfectant is sprayed, and compared with being easier under condition of normal pressure to obtain separating drying, so drastically increases atomizing effect and drying Efficiency, atomization particle is also less, even up to nanoscale.And the atomization particle more little time suspending in atmosphere is longer, just The antibacterial of same in the air of more having an opportunity is fully contacted and reaches the purpose of sterilizing.
2. the nanometer mist disinfectant injection sterilizing casing 3 due to being formed after spraying by the way of pulsation spraying, not only Improve the concentration of nanometer mist disinfectant in sterilizing casing 3, but also easily nanometer mist disinfectant is injected into various In small pipeline (as medical various endoscopies, disposable syringe etc.) and small containers (as eye-drop liquid bottle), therefore this low Warm impulse sterilization mode, is particularly well-suited to various small-sized salable spaces (as freeze dryer) and each of the interior placement of casing 3 that sterilize The sterilization of the object (as plastic catheter and plastic containers) of class non-refractory.
3. because the disinfectant of residual in the casing 3 that sterilizes is purged by the mode employing vacuum impulse simultaneously, not only Reduce manufacturing cost and the use cost of equipment, and the disinfectant of residual is removed very thorough, save sterilization and make The time of industry.
4. it is different from vaporized hydrogen peroxide sterilization technology (vhp, vaporized hydrogenperoxide), vhp needs Using the change hydrogenperoxide steam generator (more than more than 30%) of high concentration, not only corrosivity are strong, and dense with change hydrogen peroxide Degree increases, and viscosity is also gradually increased, and is also not easy in atmosphere to spread.And this technology only need to use less than 5% change peroxidating Hydrogen solution it is not required that hot conditionss, using safer.
5. the present invention is equipped with detecting system 7, can at any time the concentration of disinfectant nanometer mist be monitored it is also possible to right After elimination, the concentration of residual disinfectant nanometer mist is detected.
6. the active Hydrogen Peroxide Disinfectant of present invention cooperation uses, and has noresidue, free of contamination advantage after sterilizing, is one Plant the Sterilization and Disinfection Equipment of environmental protection.
The above, be only 1 embodiment of the application, and not the application is done with any type of restriction although this Shen Please with preferred embodiment disclose as above, but and be not used to limit the application, any those skilled in the art, do not taking off In the range of technical scheme, make a little variation using the technology contents of the disclosure above or modification is all equal to Effect case study on implementation, belongs in the range of technical scheme.

Claims (10)

1. a kind of Pulsated sterilizing equipment is it is characterised in that described Pulsated sterilizing equipment includes: liquid-storage system, separately drying system, Detecting system, spraying system, vacuum system, sterilizing casing and control system, the described drying system that separates is located at described liquid storage system Above system, and the described drying system that separates is connected with described liquid-storage system, and described liquid-storage system is used for depositing disinfectant, described point It is sequentially connected with described sterilizing casing, described spraying system from drying system, described spraying system is also dried system with described separation System, described liquid-storage system connect respectively, and described sterilizing casing is also connected respectively with described detecting system, described vacuum system, institute State control system to be all connected with described spraying system, described vacuum system, described detecting system.
2. Pulsated sterilizing equipment according to claim 1 is it is characterised in that described liquid-storage system includes reservoir, transfusion Pipe, deposits disinfectant in described reservoir, and described reservoir top is connected with the described drying system that separates, described reservoir bottom It is provided with outage, described tube for transfusion one end is connected with described outage, the described tube for transfusion other end is with described spraying system even Connect.
3. Pulsated sterilizing equipment according to claim 2 is it is characterised in that described spraying system includes blower fan, venturi Pipe and fog-spray nozzle, described sterilizing casing and described blower fan, described Venturi tube, described fog-spray nozzle, described to separate drying system suitable Secondary connection, described Venturi tube is also connected with described tube for transfusion.
4. Pulsated sterilizing equipment according to claim 3 is it is characterised in that described separation includes at least inside drying system One cavity, described cavity sidepiece is connected with described fog-spray nozzle, and described cavity bottom is connected with described reservoir.
5. Pulsated sterilizing equipment according to claim 4 is it is characterised in that described separation includes sequentially inside drying system The first cavity, the second cavity and the 3rd cavity connecting, described first cavity bottom is connected with described reservoir, and described first is empty Chamber sidepiece is connected with described fog-spray nozzle, and described 3rd cavity is also connected with described sterilizing casing, described 3rd cavity top setting There is opening, described opening is provided with closure, described 3rd cavity bottom is connected with described first cavity or reservoir.
6. the Pulsated sterilizing equipment according to any one of claim 1-5 is it is characterised in that described sterilizing casing includes casing Body, support, described box-like body is internally provided with multiple supports, described support is used for place the object of sterilizing to be sterilized.
7. Pulsated sterilizing equipment according to claim 6 is it is characterised in that described sterilizing casing also includes breathing circuit filter With vacuum meter, described breathing circuit filter is located at outside described box-like body, and described breathing circuit filter, described vacuum meter are all and institute State box-like body to connect.
8. Pulsated sterilizing equipment according to claim 7 it is characterised in that described vacuum system include being sequentially connected with true Empty pump and the vacuum tube of resistance to negative pressure, described vacuum tube is also connected with described box-like body.
9. Pulsated sterilizing equipment according to claim 8 is it is characterised in that described detecting system includes the biography being sequentially connected with Induction device, signal processing apparatus and display device, described sensing device is connected with described box-like body, described sensing device also with Spraying system connects.
10. Pulsated sterilizing equipment according to claim 9 is it is characterised in that described Pulsated sterilizing equipment is also included at least One shell, described liquid-storage system, described separation drying system, described sterilizing casing, described spraying system control system with described System is arranged at described enclosure.
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CN107802853A (en) * 2017-10-24 2018-03-16 天津市海正泰克塑胶制品有限公司 A kind of Medical efficient disinfecting washer
CN113368282A (en) * 2021-03-18 2021-09-10 郑州圣华药物食品技术开发有限公司 Pulse disinfection method for preparing ozone by using xenon excimer light source and equipment thereof

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CN204637039U (en) * 2015-03-12 2015-09-16 江阴滨江医疗设备有限公司 The pulse vacuum vapor sterilization machine
CN105597133A (en) * 2016-01-28 2016-05-25 湖北荷普药业股份有限公司 Ultra-dry fog generator

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CN2845803Y (en) * 2005-06-02 2006-12-13 武汉市江汉医疗制药设备有限公司 Electric heating type pulse vacuum sterilizing device
CN104474564A (en) * 2014-12-08 2015-04-01 老肯医疗科技股份有限公司 Energy-saving type pulsation vacuum pressure steam sterilizer
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CN106822954A (en) * 2017-03-21 2017-06-13 湖北荷普药业股份有限公司 A kind of room temperature vaporizes disinfection system
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CN107802853A (en) * 2017-10-24 2018-03-16 天津市海正泰克塑胶制品有限公司 A kind of Medical efficient disinfecting washer
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CN113368282A (en) * 2021-03-18 2021-09-10 郑州圣华药物食品技术开发有限公司 Pulse disinfection method for preparing ozone by using xenon excimer light source and equipment thereof
CN113368282B (en) * 2021-03-18 2023-08-08 郑州圣华药物食品技术开发有限公司 Pulse disinfection method for preparing ozone by xenon excimer light source and equipment thereof

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