CN106344425A - Marine shellfish bioactive peptide emulsion - Google Patents

Marine shellfish bioactive peptide emulsion Download PDF

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Publication number
CN106344425A
CN106344425A CN201610870275.XA CN201610870275A CN106344425A CN 106344425 A CN106344425 A CN 106344425A CN 201610870275 A CN201610870275 A CN 201610870275A CN 106344425 A CN106344425 A CN 106344425A
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China
Prior art keywords
parts
bioactive peptide
skin
marine shellfish
emulsion
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Pending
Application number
CN201610870275.XA
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Chinese (zh)
Inventor
刘艺鹏
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Individual
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Individual
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Priority to CN201610870275.XA priority Critical patent/CN106344425A/en
Publication of CN106344425A publication Critical patent/CN106344425A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

Abstract

The invention provides a marine shellfish bioactive peptide emulsion. A formula of the marine shellfish bioactive peptide emulsion comprises the following raw materials in parts by weight: 1 part of cyclopentasiloxane, 1 part of dicaprylyl carbonate, 1 part of bee wax, 2 parts of glycerol, 7 parts of marine shellfish bioactive peptide, 2 parts of hyaluronic acid, 1 part of xanthan gum, 3 parts of honey, 0.5 part of vitamin E acetate, 0.5 part of essence, 0.5 part of a preservative and the balance of deionized water replenished until the weight part of total raw materials is 100. The dosage and physicochemical properties of all the raw materials achieve a synergetic effect, so that the effects of eliminating wrinkles, preserving moisture and promoting cell regeneration are achieved. The PH value of the marine shellfish bioactive peptide emulsion is approximate to that of human skin, so that the marine shellfish bioactive peptide emulsion is non-irritant to the skin; after the marine shellfish bioactive peptide emulsion is used, a user can obviously feel comfortable and soft; the marine shellfish bioactive peptide emulsion is free from oily feel and has obvious effects of eliminating wrinkles, tendering skin and improving the skin color.

Description

Oceanic shellfish active peptide emulsion
Technical field
The present invention relates to cosmetic field is and in particular to the seashells of a kind of wrinkle removing moisturizing, promotion cell regeneration are active Peptide emulsion, has good wrinkle removing skin care, improves the effect of the colour of skin to skin.
Background technology
Emulsion, being a kind of liquid frost class cosmetics, because seeming pure white such as milk, being emulsion.Emulsion is as shield Skin product, maximum feature is exactly that water content is very high, can moment Glycerin, be that dry skin keeps the skin wet.Can plus emulsion To form the protecting film of frivolous ventilative in skin surface, water loss can be prevented, serve splendid moistening effect.Therefore with list The astringent of pure moisturizing type is compared, and emulsion is more suitable for using in dry season.Emulsion has good skin moistening effect, also has moisturizing Effect, is particularly suitable for the spring of drying, and season in autumn two uses, if skin is neutral it is also possible to use in winter.Spring and autumn uses When, in addition to skin-moistening effect, the extraneous weather being dried can also be isolated, prevent skin water loss too fast, it is to avoid skin Dry and cracked, peeling, be dry season go out when must skin care item.Although, many emulsions have good moisturizing effect, right In the strengthening of facial continuing care, nutritional supplementation and equilibrium function, still need and will improve further.
Content of the invention
It is an object of the invention to provide the oceanic shellfish active peptide emulsion of a kind of wrinkle removing moisturizing, promotion cell regeneration, right Skin has good wrinkle removing skin care, improves the effect of the colour of skin.
Present invention employs such technical scheme: described invention is applied to the oceanic shellfish active peptide breast of any skin Liquid, the raw material in its formula and weight ratio are respectively: 1 part of cyclopentasiloxane, 1 part of dicaprylyl carbonate, 1 part of Cera Flava, 2 parts of glycerol, 7 parts of oceanic shellfish active peptide, 2 parts of hyaluronic acid, 1 part of HANSHENGJIAO, 3 parts of Mel, 0.5 part of vitamin e acetass, 0.5 part of essence, 0.5 part of preservative, deionized water add to 100 parts.
The weight proportion of the present invention is to obtain through the present inventor's lot of experiments, and up to the practical application of 2 years Middle proof, has ideal wrinkle removing skin care, improves the effect of the colour of skin.
Heretofore described raw material:
Cyclopentasiloxane: smooth dose, the transparent volatile silicone oils of colorless and odorless, due to its volatile characteristic, frequently as cosmetic Carrier in product, helps other materials to enter skin, and can reduce surface tension, so that product is clearly smeared well.
Dicaprylyl carbonate: (carbonicacid, dioctylester), is a kind of new emollient, it has extremely dry Refreshing skin sense and good spreadability, can be compared favourably with volatile silicone oils;Meanwhile, it is to crystal type Orangic sunscreen and titanium dioxide Titanium, zinc oxide have fine dissolubility, be remarkably improved the spf value of product and lower the greasy of sunscreen in sunscreen product Sense.
Cera Flava: Cera Flava is used for beautifying skin as trophism and astringent substance, is senior natural good merchantable brand, makes mask Excellent materials, Cera Flava energy nutrition and improve subcutaneous tissue situation so as to elastic fiberss activation, prevent its hardening, promote skin soft and moist, Reduce wrinkle.External also have expert in order to prepare ointment, to improve looks and remove the report of wrinkle.
Glycerol: appearance colorless clear viscous liquids, odorless, tasteless, there is hygroscopicity, humectation, the property of softening, extremely aobvious absorb The moisture of in the air, aqueous solution is in neutrality, has good freeze-proof.
Oceanic shellfish active peptide: seashells, as a kind of large high quality protein resource being extensively easy to get of raw material, are raw The desirable feedstock of thing bioactive peptide exploitation.Oceanic shellfish active peptide is in the fields such as food industry, medicine, cosmetics and feedstuff Potential using value and prospect.There are the biological activitys such as antioxidation, antitumor, resisting hypertension, antibacterial and anticoagulation.
HANSHENGJIAO: Xanthan Gum.Xanthan gum is light yellow to white flowable powder, slightly carries stink.It is soluble in hot and cold In water, solution neutral, resistance and freeze and defrosting, insoluble in ethanol.Chance moisture dissipates, emulsifying becomes stable hydrophilic thick gel. Xanthan gum is that one kind integrates thickening, suspension, emulsifying, is stable at. best performance biogum more.It is used as multiple in the industry The stabilizer of purpose, thickening agent and processing paving auxiliary agent, include making canned with bottled food, bakery food, milk product, freezing Food, salad flavoring agent, beverage, brewage, confection, cake pattern join product etc..When making food, readily flowed, it is easy to pour out down Enter, be easy to pipeline, reduce energy resource consumption.
Hyaluronic acid: also known as Hyaluronic Acid, it is a kind of acid mucopolysaccharide.It is the tender important foundation material of skin water, itself It is also a kind of composition of human body, it has special water retention, deal is more up to 100 times of itself weight, be to send out at present The best material of moisture retention in existing nature, is referred to as preferable nature moisturizing factor.It can improve skin-nourishing metabolism, Make that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, be good Percutaneous absorption enhancer again while moisturizing. Use cooperatively with other nutritional labelings, the more preferable effect promoting alimentation can be played.
HANSHENGJIAO: unit cell polysaccharide.Xanthan gum is light yellow to white flowable powder, slightly carries stink.It is soluble in hot water or cold water In, solution neutral, resistance and freeze and defrosting, insoluble in ethanol.Chance moisture dissipates, emulsifying becomes stable hydrophilic thick gel.Yellow Virgin rubber is that one kind integrates thickening, suspension, emulsifying, is stable at. best performance biogum more.It is used as multiple mesh in the industry Stabilizer, thickening agent and processing paving auxiliary agent, include making canned and bottled food, bakery food, milk product, freezing are eaten Product, salad flavoring agent, beverage, brewage, confection, cake pattern join product etc..When making food, readily flowed, it is easy to pour out and pour into, It is easy to pipeline, reduce energy resource consumption.
Mel: the honey that the nectar that to be insecticide Apiss adopt from the spending of flowering plant is brewed in Nidus Vespae.The composition of Mel Kind except glucose, Fructose also contains various vitamin, mineral and aminoacid.1 kilogram of Mel contains the heat of 2940 cards Amount.Mel is the supersaturated solution of sugar, can produce crystallization during low temperature, generates the part being glucose, not producing crystallization of crystallization Mainly Fructose.Mel is a kind of nutritious natural nourishing food, is also one of the most frequently used tonic.According to analysis, contain There are plurality of inorganic salt with human serum concentration comparable and multiple organic acid such as vitamin, ferrum, calcium, copper, manganese, potassium, phosphorus and beneficial The trace element of health, and Fructose, glucose, amylase, oxidase, reductase etc., have nourishing, moisturize, detoxify, The effect of beauty face-whitening-nourishing, loosening bowel to relieve constipation.
Vitamin e acetass: character: faint yellow viscous fluid.Dissolubility: be soluble in alcohol, ether, acetone, chloroform, oils and fatss and its His fat solvent, is practically insoluble in water.Ve to knife injury, burn, scald, acne, senile plaque, xerosis cutiss and to ultraviolet line loss The protection of wound, reducing the aspect such as lipid peroxidation and glabrous skin has preferable effect.
Essence: be that in cosmetics, access times at most, are also a range class additive the widest.It is a kind of by artificial The redeployed mixture containing two or more spice.
Preservative: refer to stop the material of the growth of microorganism of growth of microorganism or prevention product reaction.Making up In product, the effect of preservative is protection product, is allowed to extend the shelf life of product from microorganism pollution;Guarantee product Safety, prevents consumer from being caused possible infecting by the product of microorganism pollution because using.
Deionized water: deionized water (deionized water) refer to eliminate in ionic speciess impurity after pure water.State " deionization " of border standardization body iso/tc 147 regulation is defined as: " deionized water removes deionization thing completely or by halves Matter, refers mainly to using ion exchange resin treatment method." present technique mainly produced using the method for ro reverse osmosiss.
The consumption of each raw material of the present invention and physicochemical property produce coordinative role, have the active effect that wrinkle removing moisturizing, promote carefully Born of the same parents regenerate;Ph value is close with the ph value of human body skin, to no skin irritation;Using rear substantially feel comfortably cool, soft, no greasy Sense, has obvious wrinkle removing skin care, improves the effect of the colour of skin.
The using effect Experimental comparison of the present invention: address: Dengfeng City of Henan Province Dong Guanjie " certain famous brand name cosmetology and health machine Structure ".
First group: participate in experiment number 155, be certain famous brand name cosmetology and health mechanism client women, age 18 40 years old.Using certain enterprise's reputable brand emulsion, usage cycles are 4 months, and averagely everyone is daily using 1-2 time.Experimental result: full Meaning rate 67.2%;Be satisfied with standard: using rear substantially feel comfortably cool, soft, no greasy feeling, have and significantly moisten skin care effect.
Second group: participate in experiment number 170, be certain famous brand name cosmetology and health mechanism client women, age 18 42 years old.Using oceanic shellfish active peptide emulsion of the present invention, using method is: wipes in facial skin.Usage cycles are 4 Individual month, averagely everyone was daily using 1-2 time.Experimental result: satisfaction rate 88.2%;It is satisfied with standard: to no skin irritation, use Substantially feel comfortably cool afterwards, soft, no greasy feeling, there is obvious wrinkle removing skin care, improve the effect of the colour of skin.
Experiment contrast result: emulsion of the present invention, to no skin irritation, using rear substantially feel comfortably cool, soft, No greasy feeling, has obvious wrinkle removing skin care, improves the effect of the colour of skin.
Specific embodiment
Described oceanic shellfish active peptide emulsion, the raw material in its formula and weight ratio are respectively: 1 part of cyclopentasiloxane, carbon 1 part of dioctyl phthalate, 1 part of Cera Flava, 2 parts of glycerol, 7 parts of oceanic shellfish active peptide, 2 parts of hyaluronic acid, 1 part of HANSHENGJIAO, 3 parts of Mel, 0.5 part of vitamin e acetass, 0.5 part of essence, 0.5 part of preservative, deionized water add to 100 parts.Its preparation method is:
Step one: the materials such as cyclopentasiloxane, dicaprylyl carbonate, Cera Flava are mixed and heated to 80 DEG C, constant temperature stirs 10min;
Step 2: by glycerol, oceanic shellfish active peptide, hyaluronic acid, HANSHENGJIAO, vitamin e acetass, preservative and deionization Water is mixed and heated to 80 DEG C, and constant temperature stirs 10min;
Step 3: step (one) resulting material is added in step (two) resulting material, stirs while adding, mix homogenizing 15min, adds Mel and essence to be uniformly mixed when it is cooled to 40 DEG C, stands to room temperature, sterilize, subpackage.

Claims (2)

1. a kind of oceanic shellfish active peptide emulsion is it is characterised in that the raw material in formula and weight ratio are respectively: cyclopentasiloxane 1 part, 1 part of dicaprylyl carbonate, 1 part of Cera Flava, 2 parts of glycerol, 7 parts of oceanic shellfish active peptide, 2 parts of hyaluronic acid, 1 part of HANSHENGJIAO, honeybee 3 parts of honey, 0.5 part of vitamin e acetass, 0.5 part of essence, 0.5 part of preservative, deionized water add to 100 parts.
2. according to the emulsion described in claim 1 it is characterised in that the preparation method of described oceanic shellfish active peptide emulsion is:
Step one: the materials such as cyclopentasiloxane, dicaprylyl carbonate, Cera Flava are mixed and heated to 80 DEG C, constant temperature stirs 10min;
Step 2: by glycerol, oceanic shellfish active peptide, hyaluronic acid, HANSHENGJIAO, vitamin e acetass, preservative and deionization Water is mixed and heated to 80 DEG C, and constant temperature stirs 10min;
Step 3: step (one) resulting material is added in step (two) resulting material, stirs while adding, mix homogenizing 15min, adds Mel and essence to be uniformly mixed when it is cooled to 40 DEG C, stands to room temperature, sterilize, subpackage.
CN201610870275.XA 2016-10-06 2016-10-06 Marine shellfish bioactive peptide emulsion Pending CN106344425A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610870275.XA CN106344425A (en) 2016-10-06 2016-10-06 Marine shellfish bioactive peptide emulsion

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Application Number Priority Date Filing Date Title
CN201610870275.XA CN106344425A (en) 2016-10-06 2016-10-06 Marine shellfish bioactive peptide emulsion

Publications (1)

Publication Number Publication Date
CN106344425A true CN106344425A (en) 2017-01-25

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102188332A (en) * 2011-03-31 2011-09-21 中国科学院南海海洋研究所 Cosmetic containing oceanic shellfish active peptide and preparation method and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102188332A (en) * 2011-03-31 2011-09-21 中国科学院南海海洋研究所 Cosmetic containing oceanic shellfish active peptide and preparation method and application thereof

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