CN106344145B - Hose cryoprobe and application method with seal wire guide device - Google Patents
Hose cryoprobe and application method with seal wire guide device Download PDFInfo
- Publication number
- CN106344145B CN106344145B CN201610874753.4A CN201610874753A CN106344145B CN 106344145 B CN106344145 B CN 106344145B CN 201610874753 A CN201610874753 A CN 201610874753A CN 106344145 B CN106344145 B CN 106344145B
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- seal wire
- air
- guide passage
- channel
- refrigerant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00482—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00529—Liver
- A61B2018/00535—Biliary tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
The present invention relates to hose cryoprobes and application method with seal wire guide device comprising right part protrudes into the refrigerant return-air and silk guide passage pipe and the cold head that refrigerant return-air and silk guide passage pipe right end is arranged in of human body；It is provided in the side of cold head for guiding cold head to hinder the seal wire that gear hinders pathological tissues to reach diseased region in tumour and/or channel by gear in bending channel in human body, channel；The application have can treat repeatedly, patient is painless, low-cost, easy to operate, few intercurrent disease, the identical advantage of therapeutic effect.
Description
Technical field
The present invention relates to hose cryoprobes and application method with seal wire guide device.
Background technique
Currently, existing frozen knife is all to protrude into body using a freezing cutter head, pass through bending channel example in human body at it
Gear hinders gear in tumour and/or channel to hinder pathological tissues especially difficult when reaching diseased region in such as biliary tract or enteron aisle, channel,
Surgical procedure causes high effort for.
Summary of the invention
The band seal wire reasonable, compact-sized and easy to use technical problem to be solved by the invention is to provide a kind of design
The hose cryoprobe and application method of guide device.
To solve the above problems, the technical solution used in the present invention is:
A kind of hose cryoprobe with seal wire guide device protrudes into the refrigerant return-air and silk guide passage of human body including right part
Manage and be arranged in the cold head of refrigerant return-air and silk guide passage pipe right end；It is provided in the side of cold head for guiding cold head to pass through
Bending channel in human body, gear hinders gear tumour and/or channel in hinder the seal wire of pathological tissues arrival diseased region in channel.
As a further improvement of the above technical scheme:
The flexible setting of the corresponding cold head of seal wire.
The guiding main channel of inserting seal wire is provided in refrigerant return-air and silk guide passage pipe.
Seal wire left end is exposed to the external world from the left end of guiding main channel or is provided with the right side in refrigerant return-air and silk guide passage pipe
It holds the guiding by-pass being connected to guiding main channel and seal wire passes through guiding by-pass.
It is fitted with refrigerant delivery pipe in refrigerant return-air and silk guide passage pipe, is provided with and cold head in refrigerant delivery pipe right end
Corresponding throttle orifice is provided with inlet channel in refrigerant delivery pipe, in refrigerant delivery pipe lateral wall and refrigerant return-air and seal wire
Return gas channel is formed between tube channel inner sidewall, return gas channel is connected to by throttle orifice with inlet channel.
Seal wire entrance guide sleeve is set in refrigerant return-air and silk guide passage pipe left part；Refrigerant return-air and silk guide passage pipe install
In the main through-hole of seal wire entrance guide sleeve；By-pass prot is provided on refrigerant return-air and silk guide passage pipe, by-pass prot and guiding are led
Channel connection, seal wire pass through by-pass prot.
It is provided with probe insert in the left positioning spigot of seal wire entrance guide sleeve left end, the screw thread of right end in probe insert
It is provided with locking swivel nut in hole, is provided with the core that rises in locking swivel nut, is provided with and is fixedly clamped between locking swivel nut and the core that rises
The left end of gap, refrigerant return-air and silk guide passage pipe is arranged in the gap that is fixedly clamped.
The right end of probe insert is provided with fixed ring, Fixing shrink ring connects on seal wire entrance guide sleeve left end and with screw
It connects；It is provided with the first inner hole in probe insert, the second inner hole is provided between the first inner hole and threaded hole, in-core is set rising
It is equipped with the third through-hole being connected to the first inner hole, third through-hole, the first inner hole and the second inner hole are set in refrigerant delivery pipe,
Venthole is provided on probe insert；Venthole is by the gap between the second inner hole, third through-hole and refrigerant delivery pipe and returns
The connection of gas channel；Scolding tin is provided in gap between the first inner hole and refrigerant delivery pipe；In cold head left end and refrigerant return-air
And hose connection is provided between silk guide passage pipe right end；Auxiliary pilot hole is provided on hose connection, seal wire passes through
Assist pilot hole.
The temperature range of cold head is -40 DEG C -- 60 DEG C；The diameter range of cold head is 1.8-2.4mm.
A kind of application method of the hose cryoprobe with seal wire guide device, by means of above-mentioned device；Including and it is suitable
Secondary execution following steps:
Step a: seal wire is inserted into from by-pass prot and is exposed from auxiliary pilot hole, and the end of seal wire is exposed at the right side of cold head
Side；
Step b: cold head is inserted into human body, the end guidance cold head of seal wire reaches diseased region；
Step c: seal wire is taken out out of by-pass prot；
Step d: cryoablation operation is carried out.
The beneficial effects of adopting the technical scheme are that
Compared with radiofrequency catheter thermal ablation techniques, the application have can treat repeatedly, patient is painless, it is low-cost, operation
Simply, the identical advantage of few intercurrent disease, therapeutic effect.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention.
Fig. 2 is the structural schematic diagram of present invention locking swivel nut.
Fig. 3 is the structural schematic diagram of seal wire entrance guide sleeve of the present invention.
Fig. 4 is the structural schematic diagram of refrigerant delivery pipe of the present invention.
Wherein: 1, scolding tin；2, refrigerant delivery pipe；3, probe insert；4, rise core；5, swivel nut is locked；6, fixed ring；7, seal wire
Entrance guide sleeve；8, refrigerant return-air and silk guide passage pipe；9, hose connection；10, cold head；11, seal wire；12, venthole；13,
One inner hole；14, the second inner hole；15, threaded hole；16, be fixedly clamped gap；17, third through-hole；18, main through-hole；19, by-pass prot；
20, left positioning spigot；21, return gas channel；22, inlet channel；23, throttle orifice；24, it is oriented to main channel；25, it is oriented to by-pass.
Specific embodiment
As shown in Figs 1-4, the hose cryoprobe with seal wire guide device of the present embodiment, protrudes into human body including right part
Refrigerant return-air and silk guide passage pipe 8 and the cold head 10 that 8 right end of refrigerant return-air and silk guide passage pipe is set；The one of cold head 10
Side is provided with for guiding cold head 10 to hinder gear in tumour and/or channel to hinder lesion group by gear in bending channel in human body, channel
Knit the seal wire 11 for reaching diseased region.
The flexible setting of the corresponding cold head 10 of seal wire 11.
The guiding main channel 24 of inserting seal wire 11 is provided in refrigerant return-air and silk guide passage pipe 8.
11 left end of seal wire is exposed to the external world from the left end of guiding main channel 24 or is arranged in refrigerant return-air and silk guide passage pipe 8
The guiding by-pass 25 and seal wire 11 for having right end to be connected to guiding main channel 24 pass through guiding by-pass 25.
Be fitted with refrigerant delivery pipe 2 in refrigerant return-air and silk guide passage pipe 8,2 right end of refrigerant delivery pipe be provided with
The corresponding throttle orifice 23 of cold head 10, is provided with inlet channel 22 in refrigerant delivery pipe 2,2 lateral wall of refrigerant delivery pipe with it is cold
Return gas channel 21 is formed between 8 inner sidewall of matchmaker's return-air and silk guide passage pipe, return gas channel 21 passes through throttle orifice 23 and inlet channel
22 connections.
Seal wire entrance guide sleeve 7 is set in refrigerant return-air and 8 left part of silk guide passage pipe；Refrigerant return-air and silk guide passage pipe 8
It is installed in the main through-hole 18 of seal wire entrance guide sleeve 7；It is provided with by-pass prot 19 on refrigerant return-air and silk guide passage pipe 8, bypasses
Hole 19 is connected to guiding main channel 24, and seal wire 11 passes through by-pass prot 19.
It is provided with probe insert 3 in the left positioning spigot 20 of 7 left end of seal wire entrance guide sleeve, the right end in probe insert 3
Threaded hole 15 in be provided with locking swivel nut 5, locking swivel nut 5 in be provided with the core 4 that rises, locking swivel nut 5 and the core 4 that rises between set
It is equipped with the gap 16 that is fixedly clamped, the left end setting of refrigerant return-air and silk guide passage pipe 8 is in the gap 16 that is fixedly clamped.
The right end of probe insert 3 is provided with fixed ring 6, fixed ring 6 is sleeved on 7 left end of seal wire entrance guide sleeve and uses spiral shell
Nail connection.
It is provided with the first inner hole 13 in probe insert 3, is provided in second between the first inner hole 13 and threaded hole 15
Hole 14 is provided with the third through-hole 17 being connected to the first inner hole 13, third through-hole 17, the first inner hole 13 and in the core 4 that rises
Two inner holes 14 are set in refrigerant delivery pipe 2, and venthole 12 is provided on probe insert 3；Venthole 12 by the second inner hole 14,
Gap between third through-hole 17 and refrigerant delivery pipe 2 is connected to return gas channel 21；The first inner hole 13 and refrigerant delivery pipe 2 it
Between gap in be provided with scolding tin 1.
Hose connection 9 is provided between 10 left end of cold head and refrigerant return-air and 8 right end of silk guide passage pipe；Connect in hose
Auxiliary pilot hole is provided in female connector 9, seal wire 11 passes through auxiliary pilot hole.
The application method of the present embodiment, by means of above-mentioned apparatus；Specifically includes the following steps:
Step a: seal wire 11 is inserted into from by-pass prot 19 and is exposed from auxiliary pilot hole, and the end of seal wire 11 is exposed at cold head
10 right side；
Step b: cold head 10 is inserted into human body, the end guidance cold head 10 of seal wire 11 reaches diseased region；
Step c: seal wire 11 is taken out out of by-pass prot 19；
Step d: cryoablation operation is carried out.
For example, seal wire enters biliary tract by subcutaneous puncture channel, due to tumour and pathological tissues in biliary tract bending and biliary tract
Obstruction, need seal wire to explore the way in front, cryoprobe enters biliary tract along seal wire, when cold head reach diseased region after, seal wire
It exits, cryoprobe starts cryoablation operation.
Cold head 10 of the invention reaches diseased region under the guidance of seal wire 11, in seal wire entrance guide sleeve 7, refrigerant return-air and leads
There is independent silk guide passage in silk tube channel 8, hose connection 9；Independent refrigerant return gas channel and independent silk guide passage are mutual
Not interference effect.
Using carbon freezing treatment technology, on the basis of establishing biliary drainage, pass through using hose cryoprobe
Percutaneously, the obstructive lesion of malignant tumour through liver puncture drainage channel or through being directed to biliary tract under scope directly carries out cryoablation and controls
It treats, by destroying local tumor tissue, keeps biliary tract unobstructed for a long time, improve liver function, and extend the survival of patients time limit.
10 temperature of cold head should be maintained at -40 DEG C --- 60 DEG C, both guarantees to kill tumour cell, activated cell is immune anti-
It answers, and too deep freezing injury is avoided to cause biliary tract fistula.The diameter of cold head 10 should guarantee to pass through between 1.8-2.4mm
Endoscope and it is percutaneous, through liver puncture pipeline work channel, and be soft connecting tube, be arbitrarily bent.
Certainly, the application can also first protrude into cold head, then encounter tumour and pathological tissues in biliary tract bending and biliary tract
It hinders, then seal wire is protruded into guidance cold head and passes through obstruction.
The guidance of seal wire 11 is convenient, and the flexible setting of the corresponding cold head 10 of seal wire 11 avoids influencing freezing operation, independent guiding
Main channel 24 avoids influencing each other with coolant path.It is exposed to the external world from the left end of guiding main channel 24 by 11 left end of seal wire, i.e.,
Using manufacture refrigerant return-air and the axial passage of silk guide passage pipe 8, processing is reduced, passes through guiding by-pass 25 and guiding main channel
24 form three-port structure, insert 11 convenience of seal wire；The gap 16 that is fixedly clamped fastens the left end of refrigerant return-air and silk guide passage pipe 8,
Design rationally, is connected firmly, good airproof performance；It is realized and is positioned by left positioning spigot 20, connected by fixed ring 6, anyway each portion
It is relatively rotated between part, to avoid damage to refrigerant return-air and silk guide passage pipe 8；Scolding tin 1 realizes connection and sealing, certainly, can
To use glue to cling or other welding manners.
It assists pilot hole to realize the righting to seal wire 11, guarantees that seal wire 11 is parallel with 10 axial line of cold head.
Compared with radiofrequency catheter thermal ablation techniques, the application have can treat repeatedly, patient is painless, it is low-cost, operation
Simply, the identical advantage of few intercurrent disease, therapeutic effect.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although
Present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: it still may be used
To modify to technical solution documented by previous embodiment or equivalent replacement of some of the technical features；Make
It is obvious for being combined for those skilled in the art to multiple technical solutions of the invention.And these are modified or replace
It changes, the spirit and scope for technical solution of the embodiment of the present invention that it does not separate the essence of the corresponding technical solution.
Claims (1)
1. a kind of hose cryoprobe with seal wire guide device, it is characterised in that: protrude into the refrigerant return-air of human body including right part
And silk guide passage pipe (8) and setting are in refrigerant return-air and the cold head (10) of silk guide passage pipe (8) right end；The one of cold head (10)
Side, which is provided with, hinders lesion for guiding cold head (10) to hinder to keep off tumour and/or channel in by gear in bending channel in human body, channel
Tissue reaches the seal wire (11) of diseased region；
The flexible setting of seal wire (11) corresponding cold head (10)；
The guiding main channel (24) of inserting seal wire (11) is provided in refrigerant return-air and silk guide passage pipe (8)；
Seal wire (11) left end is exposed to the external world from the left end of guiding main channel (24) or sets in refrigerant return-air and silk guide passage pipe (8)
It is equipped with the guiding by-pass (25) that right end is connected to guiding main channel (24) and seal wire (11) passes through guiding by-pass (25)；
Refrigerant delivery pipe (2) are fitted in refrigerant return-air and silk guide passage pipe (8), right end is provided in refrigerant delivery pipe (2)
Throttle orifice (23) corresponding with cold head (10) is provided with inlet channel (22) in refrigerant delivery pipe (2), in refrigerant delivery pipe
(2) return gas channel (21) are formed between lateral wall and refrigerant return-air and silk guide passage pipe (8) inner sidewall, return gas channel (21) passes through
Throttle orifice (23) is connected to inlet channel (22)；
Seal wire entrance guide sleeve (7) is set in refrigerant return-air and silk guide passage pipe (8) left part；Refrigerant return-air and silk guide passage pipe
(8) it is installed in the main through-hole (18) of seal wire entrance guide sleeve (7)；Bypass is provided on refrigerant return-air and silk guide passage pipe (8)
Hole (19), by-pass prot (19) are connected to guiding main channel (24), and seal wire (11) passes through by-pass prot (19)；
Probe insert (3) are provided in the left positioning spigot (20) of seal wire entrance guide sleeve (7) left end, in probe insert (3)
It is provided with locking swivel nut (5) in the threaded hole (15) of right end, is provided with the core that rises (4) in locking swivel nut (5), in locking swivel nut
(5) it is provided between the core that rises (4) gap that is fixedly clamped (16), the left end setting of refrigerant return-air and silk guide passage pipe (8) is being pressed from both sides
It fastens in gap (16)；
It is provided with fixed ring (6) in the right end of probe insert (3), fixed ring (6) is sleeved on seal wire entrance guide sleeve (7) left end simultaneously
It is connected with screw；The first inner hole (13) are provided in probe insert (3), are set between the first inner hole (13) and threaded hole (15)
The second inner hole (14) are equipped with, are provided with the third through-hole (17) being connected to the first inner hole (13), third through-hole in the core that rises (4)
(17), the first inner hole (13) and the second inner hole (14) are set on refrigerant delivery pipe (2), are provided with out on probe insert (3)
Stomata (12)；Venthole (12) is by the gap between the second inner hole (14), third through-hole (17) and refrigerant delivery pipe (2) and returns
Gas channel (21) connection；Scolding tin (1) is provided in gap between the first inner hole (13) and refrigerant delivery pipe (2)；In cold head
(10) hose connection (9) are provided between left end and refrigerant return-air and silk guide passage pipe (8) right end；In hose connection (9)
On be provided with auxiliary pilot hole, seal wire (11) passes through auxiliary pilot hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610874753.4A CN106344145B (en) | 2016-10-08 | 2016-10-08 | Hose cryoprobe and application method with seal wire guide device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610874753.4A CN106344145B (en) | 2016-10-08 | 2016-10-08 | Hose cryoprobe and application method with seal wire guide device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106344145A CN106344145A (en) | 2017-01-25 |
| CN106344145B true CN106344145B (en) | 2019-06-28 |
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ID=57865971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610874753.4A Active CN106344145B (en) | 2016-10-08 | 2016-10-08 | Hose cryoprobe and application method with seal wire guide device |
Country Status (1)
| Country | Link |
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| CN (1) | CN106344145B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117159104A (en) * | 2023-08-02 | 2023-12-05 | 上海玮启医疗器械有限公司 | Room septum puncture system |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2726546Y (en) * | 2004-08-19 | 2005-09-21 | 上海靶向医疗系统有限公司 | Cryoprobe for target treatment for human tumor |
| CN2787162Y (en) * | 2005-04-05 | 2006-06-14 | 杨瑞森 | Freezing dilator for oesophagus cavity |
| CN204581496U (en) * | 2015-03-17 | 2015-08-26 | 北京库蓝医疗设备有限公司 | Single use sterile hose cryoprobe |
| CN204797985U (en) * | 2015-07-09 | 2015-11-25 | 宁波胜杰康生物科技有限公司 | Novel pipe is melted in tumour refrigeration |
| CN206424141U (en) * | 2016-10-08 | 2017-08-22 | 北京库蓝医疗设备有限公司 | Hose cryoprobe flexible pipe and cold head structure with seal wire guide device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120016355A1 (en) * | 2010-07-14 | 2012-01-19 | Boston Scientific Scimed, Inc. | System and method for regulating coolant flow through a catheter and an expansion element of a cryoablation system |
-
2016
- 2016-10-08 CN CN201610874753.4A patent/CN106344145B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2726546Y (en) * | 2004-08-19 | 2005-09-21 | 上海靶向医疗系统有限公司 | Cryoprobe for target treatment for human tumor |
| CN2787162Y (en) * | 2005-04-05 | 2006-06-14 | 杨瑞森 | Freezing dilator for oesophagus cavity |
| CN204581496U (en) * | 2015-03-17 | 2015-08-26 | 北京库蓝医疗设备有限公司 | Single use sterile hose cryoprobe |
| CN204797985U (en) * | 2015-07-09 | 2015-11-25 | 宁波胜杰康生物科技有限公司 | Novel pipe is melted in tumour refrigeration |
| CN206424141U (en) * | 2016-10-08 | 2017-08-22 | 北京库蓝医疗设备有限公司 | Hose cryoprobe flexible pipe and cold head structure with seal wire guide device |
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| Publication number | Publication date |
|---|---|
| CN106344145A (en) | 2017-01-25 |
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