CN106344145A - Hose cryoprobe with guide wire guiding device and usage method - Google Patents

Hose cryoprobe with guide wire guiding device and usage method Download PDF

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Publication number
CN106344145A
CN106344145A CN201610874753.4A CN201610874753A CN106344145A CN 106344145 A CN106344145 A CN 106344145A CN 201610874753 A CN201610874753 A CN 201610874753A CN 106344145 A CN106344145 A CN 106344145A
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CN
China
Prior art keywords
seal wire
air
cold head
coolant
hose
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610874753.4A
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Chinese (zh)
Other versions
CN106344145B (en
Inventor
敖国昆
张兰锁
李虎城
张志惠
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KULAN MEDICAL APPLIANCES CO Ltd BEIJING
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KULAN MEDICAL APPLIANCES CO Ltd BEIJING
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Priority to CN201610874753.4A priority Critical patent/CN106344145B/en
Publication of CN106344145A publication Critical patent/CN106344145A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00482Digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00529Liver
    • A61B2018/00535Biliary tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231Characteristics of handpieces or probes
    • A61B2018/0262Characteristics of handpieces or probes using a circulating cryogenic fluid

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

The invention relates to a hose cryoprobe with a guide wire guiding device and a usage method. The hose cryoprobe comprises a refrigerant return air and guide wire channel tube with the right portion extending into a human body and a cold head arranged at the right end of the refrigerant return air and guide wire channel tube, wherein a guide wire for guiding the cold head to pass through an inner bent channel of the human body, an in-channel blocking tumor and/or an in-channel blocking lesion tissue to reach a diseased part. The hose cryoprobe has the advantages of being capable of achieving repeated treatment, making a patient have no pain, being low in cost, simple in operation and same in treatment effect and bringing few complications.

Description

Hose cryoprobe with seal wire guide and using method
Technical field
The present invention relates to the hose cryoprobe with seal wire guide and using method.
Background technology
At present, existing frozen knife is all to stretch into body using a freezing cutter head, passes through bending channel example in human body at it As in biliary tract or intestinal etc., passage gear to hinder in tumor and/or passage gear to hinder pathological tissues to reach especially difficult when diseased region, Operation technique causes high effort for.
Content of the invention
The technical problem to be solved is to provide a kind of reasonable in design, compact conformation and band seal wire easy to use The hose cryoprobe of guide and using method.
For solving the above problems, the technical solution used in the present invention is:
A kind of hose cryoprobe with seal wire guide, including right part stretch into the coolant return-air of human body and silk guide passage pipe with And it is arranged on coolant return-air and the cold head of silk guide passage pipe right-hand member;It is provided with for guiding cold head to pass through human body in the side of cold head In interior bending channel, passage, gear hinders gear in tumor and/or passage to hinder pathological tissues to reach the seal wire of diseased region.
Improvement further as technique scheme:
The corresponding cold head of seal wire stretches and arranges.
It is provided with the guiding main channel of plug-in mounting seal wire in coolant return-air and silk guide passage pipe.
The left end from guiding main channel for the seal wire left end is exposed to the external world or is provided with the right side in coolant return-air and silk guide passage pipe Hold the guiding by-pass connecting with guiding main channel and seal wire passes through guiding by-pass.
It is fitted with coolant delivery pipe in coolant return-air and silk guide passage pipe, be provided with and cold head in coolant delivery pipe right-hand member Corresponding throttle orifice, is provided with inlet channel in coolant delivery pipe, in coolant delivery pipe lateral wall and coolant return-air and seal wire Form return gas channel, return gas channel is connected with inlet channel by throttle orifice between channel medial wall.
It is set with seal wire entrance guide pin bushing in coolant return-air and silk guide passage pipe left part;Coolant return-air and silk guide passage pipe install In the main through hole of seal wire entrance guide pin bushing;By-pass prot, by-pass prot and guiding master are provided with coolant return-air and silk guide passage pipe Channel connection, seal wire passes through by-pass prot.
It is provided with probe insert in the left positioning spigot of seal wire entrance guide pin bushing left end, the screw thread of right-hand member in probe insert In the hole is provided with locking swivel nut, is provided with the core that rises in locking swivel nut, in locking swivel nut and rise to be provided between core and be fixedly clamped Gap, the left end of coolant return-air and silk guide passage pipe is arranged on and is fixedly clamped in gap.
The right-hand member of probe insert is provided with retainer ring, Fixing shrink ring is contained on seal wire entrance guide pin bushing left end and is connected with screw Connect;It is provided with the first endoporus in probe insert, is provided with the second endoporus between the first endoporus and screwed hole, in-core sets rising It is equipped with the third through-hole connecting with the first endoporus, in third through-hole, the first endoporus and the second endoporus suit coolant delivery pipe, Venthole is provided with probe insert;Venthole passes through the gap between the second endoporus, third through-hole and coolant delivery pipe and returns Gas channel connection;It is provided with scolding tin in gap between the first endoporus and coolant delivery pipe;In cold head left end and coolant return-air And it is provided with hose connection between silk guide passage pipe right-hand member;Hose connection set is provided with auxiliary pilot hole, seal wire passes through Auxiliary pilot hole.
The temperature range of cold head is -40 ° of c--60 ° of c;The diameter range of cold head is 1.8-2.4mm.
A kind of using method of the hose cryoprobe with seal wire guide, by means of above-mentioned device;Including and suitable Secondary execution following steps:
Step a: seal wire is inserted from by-pass prot and from assisting pilot hole to expose, the end of seal wire is exposed at the right side of cold head;
Step b: cold head is inserted human body, the end guiding cold head of seal wire reaches diseased region;
Step c: seal wire is taken out from bypass in the hole;
Step d: carry out cryoablation operation.
Have the beneficial effects that using produced by technique scheme:
Compared with radiofrequency catheter thermal ablation techniques, the application have can repeatedly treat, patient is painless, low cost, simple to operate, Few intercurrent disease, therapeutic effect identical advantage.
Brief description
Fig. 1 is the structural representation of the present invention.
Fig. 2 is the structural representation of locking swivel nut of the present invention.
Fig. 3 is the structural representation of seal wire entrance guide pin bushing of the present invention.
Fig. 4 is the structural representation of coolant delivery pipe of the present invention.
Wherein: 1, scolding tin;2nd, coolant delivery pipe;3rd, probe insert;4th, rise core;5th, locking swivel nut;6th, retainer ring;7th, seal wire Entrance guide pin bushing;8th, coolant return-air and silk guide passage pipe;9th, hose connection;10th, cold head;11st, seal wire;12nd, venthole;13rd, One endoporus;14th, the second endoporus;15th, screwed hole;16th, be fixedly clamped gap;17th, third through-hole;18th, main through hole;19th, by-pass prot; 20th, left positioning spigot;21st, return gas channel;22nd, inlet channel;23rd, throttle orifice;24th, guide main channel;25th, guide by-pass.
Specific embodiment
As Figure 1-4, the hose cryoprobe with seal wire guide of the present embodiment, stretches into human body including right part Coolant return-air and silk guide passage pipe 8 and be arranged on coolant return-air and the cold head 10 of silk guide passage pipe 8 right-hand member;In cold head 10 one Side is provided with that cold head 10 passes through bending channel in human body, gear hinders gear in tumor and/or passage to hinder pathological changes group in passage for guiding Knit the seal wire 11 reaching diseased region.
The corresponding cold head 10 of seal wire 11 stretches and arranges.
It is provided with the guiding main channel 24 of plug-in mounting seal wire 11 in coolant return-air and silk guide passage pipe 8.
The left end from guiding main channel 24 for seal wire 11 left end is exposed to the external world or arranges in coolant return-air and silk guide passage pipe 8 There is right-hand member with the guiding by-pass 25 that connect of guiding main channel 24 and seal wire 11 passes through and guides by-pass 25.
Be fitted with coolant delivery pipe 2 in coolant return-air and silk guide passage pipe 8, coolant delivery pipe 2 right-hand member be provided with The corresponding throttle orifice 23 of cold head 10, is provided with inlet channel 22 in coolant delivery pipe 2, coolant delivery pipe 2 lateral wall with cold Form return gas channel 21, return gas channel 21 passes through throttle orifice 23 and inlet channel between matchmaker's return-air and silk guide passage pipe 8 medial wall 22 connections.
It is set with seal wire entrance guide pin bushing 7 in coolant return-air and silk guide passage pipe 8 left part;Coolant return-air and silk guide passage pipe 8 It is installed in the main through hole 18 of seal wire entrance guide pin bushing 7;By-pass prot 19 is provided with coolant return-air and silk guide passage pipe 8, bypass Hole 19 is connected with guiding main channel 24, and seal wire 11 passes through by-pass prot 19.
It is provided with probe insert 3 in the left positioning spigot 20 of seal wire entrance guide pin bushing 7 left end, right-hand member in probe insert 3 Screwed hole 15 in be provided with locking swivel nut 5, be provided with the core 4 that rises in locking swivel nut 5, set between core 4 in locking swivel nut 5 and rising It is equipped with the gap 16 that is fixedly clamped, the left end of coolant return-air and silk guide passage pipe 8 is arranged on and is fixedly clamped in gap 16.
The right-hand member of probe insert 3 is provided with retainer ring 6, retainer ring 6 is sleeved on seal wire entrance guide pin bushing 7 left end and uses spiral shell Nail connects.
It is provided with the first endoporus 13 in probe insert 3, be provided with second between the first endoporus 13 and screwed hole 15 Hole 14, is provided with the third through-hole 17 connecting with the first endoporus 13, third through-hole 17, the first endoporus 13 and in the core 4 that rises In two endoporus 14 suit coolant delivery pipe 2, venthole 12 is provided with probe insert 3;Venthole 12 pass through the second endoporus 14, Gap between third through-hole 17 and coolant delivery pipe 2 is connected with return gas channel 21;The first endoporus 13 and coolant delivery pipe 2 it Between gap in be provided with scolding tin 1.
It is provided with hose connection 9 between cold head 10 left end and coolant return-air and silk guide passage pipe 8 right-hand member;In flexible pipe even Auxiliary pilot hole is provided with female connector 9, seal wire 11 passes through auxiliary pilot hole.
The using method of the present embodiment, by means of said apparatus;Specifically include following steps:
Step a: seal wire 11 is inserted from by-pass prot 19 and from assisting pilot hole to expose, the end of seal wire 11 is exposed at cold head 10 Right side;
Step b: cold head 10 is inserted human body, the end guiding cold head 10 of seal wire 11 reaches diseased region;
Step c: seal wire 11 is taken out in by-pass prot 19;
Step d: carry out cryoablation operation.
For example, seal wire enters biliary tract through subcutaneous puncture passage, due to tumor and pathological tissues in biliary tract bending and biliary tract Obstruction, need seal wire above exploring the way, cryoprobe enters biliary tract along seal wire, after cold head reaches diseased region, seal wire Exit, cryoprobe starts cryoablation operation.
The cold head 10 of the present invention reaches diseased region under seal wire 11 guiding, in seal wire entrance guide pin bushing 7, coolant return-air and lead On silk channel 8, hose connection 9, there is independent silk guide passage;Independent coolant return gas channel and independent silk guide passage are mutual Not interference effect.
Using carbon freezing treatment technology, on the basis of setting up biliary drainage, application hose cryoprobe passes through Percutaneous, directly carry out cryoablation and control through liver puncture drainage channel or through being directed to the obstructive focus of malignant tumor of biliary tract under scope Treat, by destroying local tumor tissue, keep biliary tract unobstructed for a long time, improve liver function, and extend the survival of patients time limit.
Cold head 10 temperature should be maintained at -40 ° of c-- -60 ° of c, both guarantees to kill tumor cell, and activated cell immunity is anti- Should, avoid too deep cryolesion to cause biliary tract fistula again.The diameter of cold head 10 should be it is ensured that can pass through between 1.8-2.4mm Endoscope and percutaneous, through liver puncture pipeline work passage, and be soft connecting tube, arbitrarily bend.
Certainly, the application can also first stretch into cold head, then runs into tumor and pathological tissues in biliary tract bending and biliary tract Hinder, then seal wire is stretched into guiding cold head and pass through to hinder.
Seal wire 11 guiding is convenient, and the corresponding cold head 10 of seal wire 11 stretches and arranges, it is to avoid impact freezing operation, independent leads To main channel 24, it is to avoid influence each other with coolant path.The external world is exposed to by the left end from guiding main channel 24 for seal wire 11 left end, I.e. using the axial passage manufacturing coolant return-air and silk guide passage pipe 8, reduce processing, main logical by guiding by-pass 25 and guiding Road 24 forms three-port structure, plug-in mounting seal wire 11 convenience;The gap 16 that is fixedly clamped fastens a left side for coolant return-air and silk guide passage pipe 8 End, reasonable in design, it is connected firmly, good airproof performance;Positioning is realized by left positioning spigot 20, is connected by retainer ring 6, anyway respectively Relatively rotate between part, thus avoiding damage to coolant return-air and silk guide passage pipe 8;Scolding tin 1 is realized connecting and sealing, certainly, Can be clung using glue or other welding manners.
Auxiliary pilot hole realizes the righting to seal wire 11 it is ensured that seal wire 11 is parallel with cold head 10 axial line.
Compared with radiofrequency catheter thermal ablation techniques, the application have can repeatedly treat, patient is painless, low cost, operation Simply, few intercurrent disease, therapeutic effect identical advantage.
Finally it is noted that above example, only in order to technical scheme to be described, is not intended to limit;Although With reference to the foregoing embodiments the present invention is described in detail, it will be understood by those within the art that: it still may be used To modify to the technical scheme described in previous embodiment, or equivalent is carried out to wherein some technical characteristics;Make For those skilled in the art, multiple technical schemes of the present invention are combined being obvious.And these are changed or replace Change, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.

Claims (10)

1. a kind of hose cryoprobe with seal wire guide it is characterised in that: include right part and stretch into the coolant return-air of human body And silk guide passage pipe (8) and the cold head (10) being arranged on coolant return-air and silk guide passage pipe (8) right-hand member;In cold head (10) one Side is provided with for guiding cold head (10) to pass through bending channel in human body, the interior gear of passage hinders tumor and/or the interior gear of passage hinders pathological changes Tissue reaches the seal wire (11) of diseased region.
2. the hose cryoprobe with seal wire guide according to claim 1 it is characterised in that: seal wire (11) phase Corresponding cold head (10) is stretched and is arranged.
3. the hose cryoprobe with seal wire guide according to claim 2 it is characterised in that: in coolant return-air and It is provided with the guiding main channel (24) of plug-in mounting seal wire (11) in silk guide passage pipe (8).
4. the hose cryoprobe with seal wire guide according to claim 3 it is characterised in that: seal wire (11) is left End is exposed to the external world or is provided with right-hand member and guiding in coolant return-air and silk guide passage pipe (8) from the left end of guiding main channel (24) Guiding by-pass (25) that main channel (24) connects and seal wire (11) passes through guiding by-pass (25).
5. the hose cryoprobe with seal wire guide according to claim 3 or 4 it is characterised in that: in coolant It is fitted with coolant delivery pipe (2) in return-air and silk guide passage pipe (8), be provided with and cold head (10) in coolant delivery pipe (2) right-hand member Corresponding throttle orifice (23), is provided with inlet channel (22) in coolant delivery pipe (2), coolant delivery pipe (2) lateral wall with Form return gas channel (21), return gas channel (21) passes through throttle orifice (23) between coolant return-air and silk guide passage pipe (8) medial wall Connect with inlet channel (22).
6. the hose cryoprobe with seal wire guide according to claim 5 it is characterised in that: in coolant return-air And silk guide passage pipe (8) left part is set with seal wire entrance guide pin bushing (7);Coolant return-air and silk guide passage pipe (8) are installed on seal wire and enter In the main through hole (18) of mouth guide pin bushing (7);Coolant return-air and silk guide passage pipe (8) are provided with by-pass prot (19), by-pass prot (19) connect with guiding main channel (24), seal wire (11) passes through by-pass prot (19).
7. the hose cryoprobe with seal wire guide according to claim 6 it is characterised in that: lead in seal wire entrance It is provided with probe insert (3), the screwed hole (15) of right-hand member in probe insert (3) in the left positioning spigot (20) of set (7) left end Inside it is provided with locking swivel nut (5), is provided with the core that rises (4) in locking swivel nut (5), set between locking swivel nut (5) and the core that rises (4) It is equipped with the gap that is fixedly clamped (16), the left end of coolant return-air and silk guide passage pipe (8) is arranged in the gap that is fixedly clamped (16).
8. the hose cryoprobe with seal wire guide according to claim 7 it is characterised in that: in probe insert (3) right-hand member is provided with retainer ring (6), and retainer ring (6) is sleeved on seal wire entrance guide pin bushing (7) left end and uses mode connects for screw;? It is provided with the first endoporus (13) in probe insert (3), between the first endoporus (13) and screwed hole (15), be provided with the second endoporus (14), it is provided with the third through-hole (17) connecting with the first endoporus (13), third through-hole (17), the first endoporus in the core that rises (4) (13), and on the second endoporus (14) suit coolant delivery pipe (2), venthole (12) is provided with probe insert (3);Give vent to anger Hole (12) is connected by the gap between the second endoporus (14), third through-hole (17) and coolant delivery pipe (2) and return gas channel (21) Logical;It is provided with scolding tin (1) in gap between the first endoporus (13) and coolant delivery pipe (2);Cold head (10) left end with cold It is provided with hose connection (9) between matchmaker's return-air and silk guide passage pipe (8) right-hand member;Hose connection (9) is provided with auxiliary Pilot hole, seal wire (11) passes through auxiliary pilot hole.
9. the hose cryoprobe with seal wire guide according to claim 8 it is characterised in that: cold head (10) Temperature range is -40 ° of c -60 ° of c;The diameter range of cold head (10) is 1.8-2.4mm.
10. a kind of using method of the hose cryoprobe with seal wire guide it is characterised in that: by means of aforesaid right will Seek the device described in any one of 1-9;Including and sequentially carry out following steps:
Step a: seal wire (11) is inserted from by-pass prot (19) and exposes from auxiliary pilot hole, the end of seal wire (11) is exposed at cold The right side of head (10);
Step b: cold head (10) is inserted human body, end guiding cold head (10) of seal wire (11) reaches diseased region;
Step c: seal wire (11) is taken out in by-pass prot (19);
Step d: carry out cryoablation operation.
CN201610874753.4A 2016-10-08 2016-10-08 Hose cryoprobe and application method with seal wire guide device Active CN106344145B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610874753.4A CN106344145B (en) 2016-10-08 2016-10-08 Hose cryoprobe and application method with seal wire guide device

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Application Number Priority Date Filing Date Title
CN201610874753.4A CN106344145B (en) 2016-10-08 2016-10-08 Hose cryoprobe and application method with seal wire guide device

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CN106344145B CN106344145B (en) 2019-06-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117159104A (en) * 2023-08-02 2023-12-05 上海玮启医疗器械有限公司 Room septum puncture system

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2726546Y (en) * 2004-08-19 2005-09-21 上海靶向医疗系统有限公司 Cryoprobe for target treatment for human tumor
CN2787162Y (en) * 2005-04-05 2006-06-14 杨瑞森 Freezing dilator for oesophagus cavity
US20120016355A1 (en) * 2010-07-14 2012-01-19 Boston Scientific Scimed, Inc. System and method for regulating coolant flow through a catheter and an expansion element of a cryoablation system
CN204581496U (en) * 2015-03-17 2015-08-26 北京库蓝医疗设备有限公司 Single use sterile hose cryoprobe
CN204797985U (en) * 2015-07-09 2015-11-25 宁波胜杰康生物科技有限公司 Novel pipe is melted in tumour refrigeration
CN206424141U (en) * 2016-10-08 2017-08-22 北京库蓝医疗设备有限公司 Hose cryoprobe flexible pipe and cold head structure with seal wire guide device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2726546Y (en) * 2004-08-19 2005-09-21 上海靶向医疗系统有限公司 Cryoprobe for target treatment for human tumor
CN2787162Y (en) * 2005-04-05 2006-06-14 杨瑞森 Freezing dilator for oesophagus cavity
US20120016355A1 (en) * 2010-07-14 2012-01-19 Boston Scientific Scimed, Inc. System and method for regulating coolant flow through a catheter and an expansion element of a cryoablation system
CN204581496U (en) * 2015-03-17 2015-08-26 北京库蓝医疗设备有限公司 Single use sterile hose cryoprobe
CN204797985U (en) * 2015-07-09 2015-11-25 宁波胜杰康生物科技有限公司 Novel pipe is melted in tumour refrigeration
CN206424141U (en) * 2016-10-08 2017-08-22 北京库蓝医疗设备有限公司 Hose cryoprobe flexible pipe and cold head structure with seal wire guide device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117159104A (en) * 2023-08-02 2023-12-05 上海玮启医疗器械有限公司 Room septum puncture system

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