CN106309952B - A kind of Chinese herbal medicine for oral administration and preparation method thereof for treating headstroke - Google Patents
A kind of Chinese herbal medicine for oral administration and preparation method thereof for treating headstroke Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K35/63—Arthropods
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention discloses a kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 25-40 parts of Radix Astragali, 10-20 parts of Radix Angelicae Sinensis, 8-15 parts of peach kernel, 12-25 parts of safflower, 6-10 parts of ramulus cinnamomi, 8-15 parts of Rhizoma Gastrodiae, 9-15 parts of radix achyranthis bidentatae, 9-25 parts of balsamine, 8-15 parts of uncaria, 6-15 parts of dragon's blood, 7-15 parts of pheretima, 6-15 parts of agkistrodon, 3-10 parts of centipede, 2-7 parts of leech, it is worm 3-10 parts complete, 6-10 parts of Radix Glycyrrhizae.The Chinese herbal medicine for oral administration is to cause internal organs imbalance of yin and yang, qi and blood against offending brain and wind, fire, phlegm, the stasis of blood this pathology in unrest by the factors such as internal injury product damage, feelings will, diet or exopathogen for headstroke, with help healthy tendency, reinvigoration for primary principle of reatment, assistant is with the insect medicine acupuncture-stimulating blood stasis dispersing altered of doing good works away, it is proper to choose medicinal material compatibility, with nourishing qi and blood, activating microcirculation and removing stasis medicinal, relieve the wind syndrome dredging collateral and other effects, treating both manifestation and root cause of disease, it is significant in efficacy.
Description
Technical field
The invention belongs to Chinese medicine technical fields, and in particular to a kind of Chinese herbal medicine for oral administration for treating headstroke and its preparation
Method.
Background technique
Headstroke also name " stroke ", be caused by the factors such as internal injury product damage, feelings will, diet or exopathogen internal organs imbalance of yin and yang,
Qi and blood against brain is offended in unrest, occur blood overflow that brain is outer or the resistance of brain vessle-Bi symptom-complex is caused is flutterred with suddenly dusk, senseless, hemiplegia,
Facial paralysis, dysphonia are flutterred and rarely seen hemiplegia, a kind of illness that facial paralysis is primary symptom without dusk.Doctor trained in Western medicine is by disease
Rationality matter is divided into cerebral haemorrhage stroke and Ischemic Stroke.Headstroke has high incidence, high mortality, high disability rate and height
The serious disease of recurrence rate.There are millions of morbidity examples, nearly 1/4 death in the whole world every year, and survivor also has different journeys
The disability rate of degree, is one of big cause of death of the mankind three, and China is one of high-incidence country of headstroke.
Although Western medicine is play an important role in the treatment of wind disease in brain, can have in long-term administration a large amount of poison,
Side effect, not using resuming treatment.Therefore when with drug therapy such disease, it is desirable that safely, effectively, toxic side effect it is few
Just it is particularly important.China's traditional medicine just had record to such disease and is controlled before thousands of years in Huangdi's Internal Classics
It treats, ancient Chinese medicine doctor also has different research and discussion to the cause of disease, the therapy etc. of this disease.Have with Chinese medicine treatment headstroke and takes effect
Fastly, the features such as adverse reaction is small, lasting medicine, therefore increase the research to Chinese medicine compound prescription and just shown with for treatment headstroke
It obtains particularly important.
Application No. is 201610027216.6 patents of invention announce a kind of Chinese materia medica preparation for treating ischemia apoplexy and its
Preparation method, a kind of Chinese materia medica preparation for treating ischemia apoplexy, it is made of following bulk pharmaceutical chemicals: rattan wingceltis, Root of Girald Larkspur, coal
Grass, radix ranunculi ternati, gold boiling grass, resina liquidamberis, herba passiflorae wilsonii, Shishou Pu, cornu caprae hircus, the vine of multiflower knotweed, ardisia japonica, bluish dogbane, helps virtue at campanulaceae
Rattan, hance rosewood stem or root, berba aristolochiae mollissimae, whiteflower cacalia seed, citron, mast cotyledon, seaweed, Alpinia henryik Schum, chicken muscle ginseng, Rhizoma Atractylodis Macrocephalae.Application number
201510700085.9 patents of invention, Shen Qing Publication are treated the Chinese materia medica preparation of headstroke, are prepared by following raw materials: sponge gourd
Network, oriental wormwood, olibanum, Radix Angelicae Sinensis, ramulus mori, product reality, Divine Comedy, dandelion, rheum officinale, Rhizoma Atractylodis Macrocephalae, radix saposhnikoviae, radix paeoniae rubra, jujube, river Chinese herbaceous peony, radix bupleuri, horse
Qian Zi, Huang Mao, dried orange peel, Samson St Johswort, uncaria, field pennycress, structure offer sacriffices to the gods or the spirits of the dead son, Asiatic plantain, radix achyranthis bidentatae, ramulus cinnamomi, the fleece-flower root, ginkgo leaf.These
Not only dosage is big on prescription for Chinese materia medica preparation, and stresses promoting blood circulation and removing obstruction in channels, calming the liver to stop the wind and ignore " healthy tendency deposit in, heresy can not be done "
It is basic, do not embody dialectical under organic conception of Chinese medicine completely to treat.
Summary of the invention
In view of this, in view of the deficiencies of the prior art, it is an object of the present invention to provide it is a kind of treat headstroke it is for oral administration in
Herbal medicine causes internal organs imbalance of yin and yang, qi and blood against rushing in unrest for headstroke by the factors such as internal injury product damage, feelings will, diet or exopathogen
Violate brain and wind, fire, phlegm, the stasis of blood this pathology, with help healthy tendency, reinvigoration for primary principle of reatment, helps with the worm altered of doing good works away
Class medicine acupuncture-stimulating blood stasis dispersing, choose medicinal material compatibility it is proper, have nourishing qi and blood, activating microcirculation and removing stasis medicinal, relieve the wind syndrome dredging collateral and other effects, treating both manifestation and root cause of disease,
It is significant in efficacy.
The present invention also provides a kind of preparation methods of Chinese herbal medicine for oral administration for treating headstroke.
In order to achieve the above objectives, the invention adopts the following technical scheme:
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 25-40 parts of Radix Astragali, Radix Angelicae Sinensis 10-
20 parts, 8-15 parts of peach kernel, 12-25 parts of safflower, 6-10 parts of ramulus cinnamomi, 8-15 parts of Rhizoma Gastrodiae, 9-15 parts of radix achyranthis bidentatae, 9-25 parts of balsamine,
It is 8-15 parts of uncaria, 6-15 parts of dragon's blood, 7-15 parts of pheretima, 6-15 parts of agkistrodon, 3-10 parts of centipede, 2-7 parts of leech, worm 3-10 parts complete
With 6-10 parts of Radix Glycyrrhizae.
Further, the raw material including following parts by weight: 25 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis, 10 parts of peach kernel, 15 parts of safflower,
7 parts of ramulus cinnamomi, 10 parts of Rhizoma Gastrodiae, 10 parts of radix achyranthis bidentatae, 15 parts of balsamine, 11 parts of uncaria, 7 parts of dragon's blood, 7 parts of pheretima, 6 parts of agkistrodon, Wu
4 parts of centipede, 3 parts of leech, 4 parts of full worm and 10 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) various raw materials are weighed to crush, medicinal powder is prepared；
(2) above-mentioned medicinal powder is prepared into granule, pill or capsule.
Further, the pill in the step (2) is prepared by the following steps:
(1) medicinal powder, fecula, distilled water are modulated into bolus, the bolus is prepared into molding pill；
(2) the molding pill is polished, the pill after being polished gets product pill after dry；
(3) the finished product pill is packed, obtains product.
Further, the bolus modulated process are as follows: take 60-100 parts of distilled water, be added fecula 20-40 parts, mild fire tanning
At being poured into container after paste, medicinal powder is then added and stirs evenly up to bolus.
Further, the drying drying process in the step (2) are as follows: the pill after the polishing is put into baking oven,
Pill water content < 10% after being dried to polishing at 50-70 DEG C is to get finished product pill.
Pharmacology of various herbs, which act on, in the present invention is:
Radix Astragali, the sweet temperature of property, returns spleen, lung channel.Have effects that tonifying Qi and lifting yang, invigorating qi for consolidating superficies.Contain glycoside, polysaccharide, Huang
Ketone compounds etc..
Radix Angelicae Sinensis, property is sweet, pungent, warm, returns liver, the heart, the spleen channel.Have effects that replenishing and activating blood, menstruction regulating and pain relieving, relax bowel and defecation.Contain
There are nopinene, australene, containing organic acid, carbohydrate, amino acid etc..
Peach kernel, property is bitter, sweet, flat, return heart, liver, large intestine channel.With promoting blood circulation, relax bowel and defecation, relieving cough and asthma effect.
Contain lipid, amino acid, protein, microelement etc..
Safflower, property is pungent, warm, converge to heart and liver channels.Have effects that blood circulation, stasis-dispelling and pain-killing.Contain carthamone, newly red
Flower glycosides etc..
Ramulus cinnamomi, property acrid, sweet, warm, return heart, lung, bladder meridian.With sweating expelling pathogenic factors from muscles and skin, the effect of warming meridian, helps yang transforming qi.
Contain volatile oil, cinnaldehydrum, phenols, organic acid etc..
Rhizoma Gastrodiae, property sweet and neutral, return liver warp.With Inflammation Zhijing, the effect of suppressing liver-YANG, dispelling wind and removing obstruction in the meridians.Containing Gastrodine,
Gastrodia elata genin, β-steroid paddy alcohol, vitamin A, a variety of amino acid etc..
Radix achyranthis bidentatae, property is bitter, sweet, sour, puts down, returns liver and kidney channel.With blood circulation, nourishing liver and kidney, strengthening the bones and muscles, promoting diuresis for stranguria draws
The effect of fiery (blood) downlink.Contain triterpenoid saponin, polysaccharide, arginine etc..
Balsamine, property is sweet, slight bitter, and temperature returns liver and kidney channel.With blood circulation, dispelling wind and eliminating dampness detoxify desinsection the effect of.Contain
There is flower containing various anthocyanins, Kaempferol, Quercetin etc..
Uncaria, property is sweet, cool, returns liver, pericardium channel.With The flat liver of heat-clearing, the effect of Inflammation Zhijing.Containing there are many indoles lifes
Alkaloids, flavone compound etc..
Dragon's blood, property is sweet, salty, flat, return liver warp.With promoting blood circulation analgesic therapy, the effect of removing blood stasis and hemostasis, expelling pus and promoting granulation.Contain dragon's blood
Element, flavanols etc..
Pheretima, property is salty, cold, returns liver, spleen, bladder meridian.With clearing away heat and relieving the wind syndrome, the effect of dredging collateral is relievingd asthma, diuresis.Containing more
Kind amino acid, microelement lumbrifebrine etc..
Agkistrodon, property is sweet, salty, warm, enters liver, the spleen channel.With wind-dispelling, the effect of dredging collateral, relieving convulsion, main apoplexy, arthritis with fixed pain caused by dampness is meciless,
Spasm of muscles and vessels, mouth face is oblique, hemiplegia, arthralgia, and strong wind scabies leprosy and storm wind itch, flaccidity of lower limbs cannot be stood long.Contain fibrin ferment
Sample substance, esterase and 3 kinds of anticoagulative substances etc..
Centipede, property is pungent, warm, return liver warp.Have effects that relieve the wind syndrome antispastic, dispersing pathogen accumulation, remove obstruction in channels to relieve pain.Contain histamine sample
Substance and hemolytic protein, a variety of amino acid, microelement, carbohydrate, albumen etc..
Leech, property is salty, bitter, flat, return liver warp.With blood-breaking dysmenorrhea, the effect of by stagnation resolvation disease.Containing protein, hirudin,
Antithromboxin etc..
Full worm, property is pungent, flat, return liver warp.Have effects that Inflammation Zhijing, dispersing pathogen accumulation, remove obstruction in channels to relieve pain.With similar snake venom
Neurotoxic protein, lecithin, scorpion toxin etc..
Radix Glycyrrhizae, property is sweet, flat, return heart, lung, spleen, stomach meridian.With invigorating middle warmer and replenishing QI, expelling phlegm and arresting coughing, relieving spasm to stop pain, mediation property of medicine
The effect of.Contain licoflavone, polysaccharide, amino acid, alkaloid etc..
The beneficial effects of the present invention are:
1, the no matter specific parting of headstroke is apoplex involving the channels and collaterals or Hitting Viscera, mostly with imbalance of yin and yang, qi and blood it is inverse disorderly, on offend brain
And based on wind, fire, phlegm, the stasis of blood, and etiology and pathogenesis mostly induces on the basis of internal injury product is damaged, therefore the present invention is directed to headstroke by interior
Hurt the factors such as product damage, feelings will, diet or exopathogen cause internal organs imbalance of yin and yang, qi and blood against offend in unrest brain and wind, fire, phlegm, the stasis of blood this
A pathology, with help healthy tendency, reinvigoration for primary principle of reatment, assistant chooses medicine with the insect medicine acupuncture-stimulating blood stasis dispersing altered of doing good works away
Material compatibility is proper, has nourishing qi and blood, activating microcirculation and removing stasis medicinal, relieve the wind syndrome dredging collateral and other effects, treating both manifestation and root cause of disease is significant in efficacy.
2, for oral administration Chinese herbal medicine of the present invention for treating headstroke be using Radix Astragali, Radix Angelicae Sinensis, ramulus cinnamomi and radix achyranthis bidentatae as monarch drug in a prescription,
The middle sweet temperature of Radix Astragali, has effects that tonifying Qi and lifting yang, invigorating qi for consolidating superficies；Radix Angelicae Sinensis is sweet, pungent, warm, and there is replenishing and activating blood, menstruation regulating to stop
Bitterly；Ramulus cinnamomi acrid, sweet, warm, warming meridian, helps yang transforming qi；Radix achyranthis bidentatae is bitter, sweet, sour, puts down, dispelling stasis of blood and stimulating the menstrual flow, nourishing liver and kidney, strengthening tendons
Bone；This four tastes Chinese medicine bowl spares has logical, benefit, without rushing down, to have the effect of tonifying Qi and blood, building up healthful vital energy, warming meridian without stagnant, logical.
Using peach kernel, safflower, Rhizoma Gastrodiae, uncaria, balsamine and dragon's blood as ministerial drug, wherein peach kernel settle, mostly tangible hemostasis with it, safflower
Light liter is floating, and hemostasis is mostly used it without place person is determined in whole body, and Rhizoma Gastrodiae mutually must be used with uncaria, and no matter the cold and heat and asthenia and sthenia of illness can all close
The effect of with Inflammation Zhijing, suppressing liver-YANG is played；And balsamine is sweet, slight bitter, temperature, blood circulation, wind-expelling pain-stopping, dragon's blood
Sweet, salty, flat, invigorate blood circulation analgesic therapy, removing blood stasis and hemostasis, dragon's blood and balsamine share hemostasis and do not stay the stasis of blood；Therefore ministerial drug has Inflammation Zhijing, puts down
The effect of pressing down liver-yang, hemostasia and dissipation blood stasis.Using pheretima, full worm, agkistrodon, centipede and leech as adjutant, wherein pheretima clearing away heat and relieving the wind syndrome is logical
Network, full worm dredging collateral relieving convulsion, agkistrodon wind-damp dispelling, saturating muscles and bones, centipede relieve the wind syndrome antispastic are removed obstruction in channels to relieve pain, and leech is by stagnation resolvation disease, this five tastes
Worm pharmacological property is apt to walk to alter, outer channels and collaterals, can activating microcirculation and removing stasis medicinal, wind and removing obstruction in channels can be searched again.It is to make medicine with Radix Glycyrrhizae, it can invigorating middle warmer and replenishing QI, slow
Anxious analgesic, and can harmonizing various medicinal property, clearing heat and detoxicating.
3, according to clinical verification, significant in efficacy, total effective rate can for the Chinese herbal medicine for oral administration for the treatment of headstroke prepared by the present invention
Reach 87.07%, and medicinal peace, does not occur toxic side effect.
4, invention is used to treat the Chinese herbal medicine for oral administration of headstroke, can through crushing and etc. be fabricated to pill,
Preparation process Chinese medicine material that is easy, easily controllable, selecting is low in cost, is suitable for producing in enormous quantities.
Specific embodiment
The invention will be further described combined with specific embodiments below, and the weight in the embodiment of the present invention counts parts by weight
Meter.
Embodiment 1
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 40 parts of Radix Astragali, 20 parts of Radix Angelicae Sinensis,
15 parts of peach kernel, 25 parts of safflower, 10 parts of ramulus cinnamomi, 15 parts of Rhizoma Gastrodiae, 15 parts of radix achyranthis bidentatae, 25 parts of balsamine, 15 parts of uncaria, 15 parts of dragon's blood,
15 parts of pheretima, 15 parts of agkistrodon, 10 parts of centipede, 7 parts of leech, 10 parts of full worm and 10 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4500r/min revolving speed using cooking machine is crushed, then
250 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 100 parts of distilled water are weighed to be put into clean stainless-steel pan, 40 parts of fecula are then added, mild fire is kept stirring
It is poured into Stainless steel basin after being brewed into paste, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by medicine
Group is prepared into molding pill with Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 8% to get finished product pill that pill water content is dried at 60 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 2
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 35 parts of Radix Astragali, 17 parts of Radix Angelicae Sinensis,
13 parts of peach kernel, 20 parts of safflower, 8 parts of ramulus cinnamomi, 13 parts of Rhizoma Gastrodiae, 12 parts of radix achyranthis bidentatae, 19 parts of balsamine, 14 parts of uncaria, 10 parts of dragon's blood,
11 parts of dragon, 11 parts of agkistrodon, 5 parts of centipede, 3 parts of leech, 5 parts of full worm and 8 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4500r/min revolving speed using cooking machine is crushed, then
250 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 70 parts of distilled water are weighed to be put into clean stainless-steel pan, 25 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 8% to get finished product pill that pill water content is dried at 70 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 3
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 30 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis,
10 parts of peach kernel, 18 parts of safflower, 7 parts of ramulus cinnamomi, 10 parts of Rhizoma Gastrodiae, 10 parts of radix achyranthis bidentatae, 19 parts of balsamine, 14 parts of uncaria, 10 parts of dragon's blood,
11 parts of dragon, 11 parts of agkistrodon, 5 parts of centipede, 3 parts of leech, 5 parts of full worm and 8 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4500r/min revolving speed using cooking machine is crushed, then
300 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 80 parts of distilled water are weighed to be put into clean stainless-steel pan, 30 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 8% to get finished product pill that pill water content is dried at 65 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 4
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 32 parts of Radix Astragali, 16 parts of Radix Angelicae Sinensis,
12 parts of peach kernel, 17 parts of safflower, 8 parts of ramulus cinnamomi, 12 parts of Rhizoma Gastrodiae, 11 parts of radix achyranthis bidentatae, 16 parts of balsamine, 12 parts of uncaria, 9 parts of dragon's blood,
10 parts of dragon, 10 parts of agkistrodon, 4 parts of centipede, 4 parts of leech, 6 parts of full worm and 8 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4500r/min revolving speed using cooking machine is crushed, then
280 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 90 parts of distilled water are weighed to be put into clean stainless-steel pan, 35 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 8% to get finished product pill that pill water content is dried at 60 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 5
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 28 parts of Radix Astragali, 13 parts of Radix Angelicae Sinensis,
10 parts of peach kernel, 12 parts of safflower, 6 parts of ramulus cinnamomi, 10 parts of Rhizoma Gastrodiae, 10 parts of radix achyranthis bidentatae, 14 parts of balsamine, 10 parts of uncaria, 8 parts of dragon's blood,
8 parts of dragon, 7 parts of agkistrodon, 3 parts of centipede, 3 parts of leech, 4 parts of full worm and 6 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4000r/min revolving speed using cooking machine is crushed, then
250 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 70 parts of distilled water are weighed to be put into clean stainless-steel pan, 25 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 6% to get finished product pill that pill water content is dried at 50 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 6
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 25 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis,
10 parts of peach kernel, 15 parts of safflower, 7 parts of ramulus cinnamomi, 10 parts of Rhizoma Gastrodiae, 10 parts of radix achyranthis bidentatae, 15 parts of balsamine, 11 parts of uncaria, 7 parts of dragon's blood,
7 parts of dragon, 6 parts of agkistrodon, 4 parts of centipede, 3 parts of leech, 4 parts of full worm and 10 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4000r/min revolving speed using cooking machine is crushed, then
250 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 80 parts of distilled water are weighed to be put into clean stainless-steel pan, 30 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 5% to get finished product pill that pill water content is dried at 60 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 7
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 28 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis,
8 parts of peach kernel, 13 parts of safflower, 6 parts of ramulus cinnamomi, 8 parts of Rhizoma Gastrodiae, 9 parts of radix achyranthis bidentatae, 9 parts of balsamine, 8 parts of uncaria, 6 parts of dragon's blood, 7 parts of pheretima,
6 parts of agkistrodon, 3 parts of centipede, 2 parts of leech, 3 parts of full worm and 10 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4000r/min revolving speed using cooking machine is crushed, then
280 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 90 parts of distilled water are weighed to be put into clean stainless-steel pan, 35 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 7% to get finished product pill that pill water content is dried at 60 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Embodiment 8
A kind of Chinese herbal medicine for oral administration for treating headstroke, the raw material including following parts by weight: 32 parts of Radix Astragali, 11 parts of Radix Angelicae Sinensis,
9 parts of peach kernel, 13 parts of safflower, 8 parts of ramulus cinnamomi, 12 parts of Rhizoma Gastrodiae, 11 parts of radix achyranthis bidentatae, 15 parts of balsamine, 12 parts of uncaria, 8 parts of dragon's blood, pheretima
8 parts, 8 parts of agkistrodon, 3 parts of centipede, 2 parts of leech, 3 parts of full worm and 8 parts of Radix Glycyrrhizae.
A kind of preparation method of Chinese herbal medicine for oral administration that treating headstroke, comprising the following steps:
(1) raw material for having been removed impurity is weighed, 1min is crushed with 4000r/min revolving speed using cooking machine is crushed, then
280 meshes are crossed, extracting screen underflow obtains medicinal powder；
(2) above-mentioned medicinal powder is prepared into pill.
Wherein pill is prepared by the following steps:
(1) 60 parts of distilled water are weighed to be put into clean stainless-steel pan, 20 parts of fecula are then added, mild fire, which is kept stirring, to be endured
It is poured into Stainless steel basin after paste is made, medicinal powder is added in Stainless steel basin and stirs to obtain bolus, by bolus
Molding pill is prepared into Chinese medicinal pills preparing machine；
(2) above-mentioned molding pill is put into after being polished in polishing case, the pill after being polished；Pill after polishing is equal
On pallet, pallet is put into baking oven even bulk storage, and it is 5% to get finished product pill that pill water content is dried at 50 DEG C；
(3) it collects finished product pill and is distributed into bag, every bag of 10g is then shut off pellet processing machine, cleans pill machine equipment.
Clinical test
One, general information
From in July, 2013 in July, 2016, treat Patients with Stroke totally 178 (women 73, male 105), the age
Between 42-75 years old.
Two, diagnostic criteria
Stroke diagnosis standard: (1) confused servant, senseless, hemiplegia, hemianesthesia, facial paralysis, speech be not suddenly
The performance of the specific clinicals such as benefit.The rarely seen dizziness of mild case, hemianesthesia, facial paralysis, hemiplegia etc..(2) more Acute onsets are good to send out
In 40 years old or more age.(3) before morbidity to have the premonitory symptoms such as dizziness, headache, limbs side numbness more.(4) often there are dizziness, head
Bitterly, the medical histories such as palpitaition, morbidity disorder of emotion, the improper diet or inducements such as tired.
Three, efficacy assessment standard
It is evaluated according to " apoplexy diagnosis and efficacy assessment standard ":
(1) basic to cure: patient's associated clinical symptoms disappear substantially, and disability degree is at I grade hereinafter, muscle strength level is substantially extensive
It is multiple to arrive normally；
(2) effective: patient clinical symptom is obviously improved, and daily basic living can take care of oneself, and muscle strength level improves II grade or more；
(3) effectively: patient clinical symptom, sign have certain improvement, and muscle strength level is at I grade or more, but daily life cannot
It takes care of oneself；
(4) invalid: patient clinical symptom, sign are obviously improved without any.
Four, therapeutic scheme
The Chinese herbal medicine for oral administration of the treatment headstroke is suitable for the treatment each card type of headstroke, and in therapeutic process, patient is random
Take finished product pill made from present example 1-8, specific instructions of taking is postprandial 1 hour warm water delivery service, once a bag, one
Day 3 times；Pungent greasy, the cold and cool food of duration of medication fasting；The 2 Monday courses for the treatment of, depending on the clinical features 2-4 course for the treatment of of medication.
Five, statistical result
Basic healing 106, effective 34, effective 15, invalid 23, total effective rate 87.07%.
Typical case
Case 1: Dai, male 63 years old, are engaged in agriculture.Patient's early winter in 2015 because " cerebral hemorrhage " occur right side limb activity it is unfavorable,
Alleviate after treatment.Because occurring dizziness vomiting, astasia, right side disorder of limb's activity suddenly after disagreeing with household after half a year, enter
It is diagnosed as after institute " cerebral infarction ", routine care treatment is outer, effective obvious after taking 2 courses for the treatment of of this drug.Effect of follow-up visit by telephone after half a year
Without recurrence.
Case 2: it is remaining certain, male, 61 years old, retired worker.Its household has left hand to hold suddenly before giving an oral account half a month when patient is admitted to hospital
Voluntarily alleviate after several minutes powerless.There is within 2 hours before the onset of being admitted to hospital left hand and left side face is powerless, aphasia is diagnosed as " lacking
Hemorrhagic cerebral apoplexy ".Routine care treatment is outer, basic to cure after taking 2 courses for the treatment of of this drug.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 3: Mr. Wang, male, 57 years old, worker.Patient likes tobacco and wine usually, occurs right side before hypertension history 10 years, 3 months
Limb activity is unfavorable, with dizziness, without nausea and vomiting.Look into head CT: right side thalamus, left side cerebellar infarction stove.Through invigorating blood circulation after in hospital
After the treatment such as thrombolysis, blood pressure lowering, still there is the right side unfavorable presence of limb activity.For further rehabilitation, 2.5 courses for the treatment of of this drug are taken
Afterwards, basic to cure.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 4: Mr. Lin, female, 70 years old, retired worker.It was hospitalized for treatment before one month with " three days out of strength of side limbs ".Physical examination mouth
Tongue skew, aphasia, left limb numbness, hypermyotonia, right side body is normal, Consciousness, and tentative diagnosis is " in brain
Wind (apoplex involving the channels and collaterals) ".Patient is strongly required to give Chinese traditional treatment in addition to physiotherapy, and after taking 3 courses for the treatment of of this drug, speech is clear
Clear, left side Muscle tensility restores, basic to cure.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 5: section, female, 43 years old, cadre.Patient is admitted to hospital because of " lower left side limb activity unfavorable, glossolalia 6 months "
Treatment.Household describes that the lower left side extremity numbness that happens suddenly after the fatigue that worked before its half a year, activity is unfavorable, nausea and vomiting, is urinary and fecal inconvenience.
It looked into head CT " cerebral hemorrhage " about 35ml at that time, and after urgent row " removing cranium valve decompression ", left lower left side limbs disturbance.It takes
After 3 courses for the treatment of of this drug, left lower extremity function is obviously improved, and daily life can take care of oneself, effective obvious.Effect of follow-up visit by telephone is without multiple after half a year
Hair.
Case 6: Xing, male, 56 years old, worker.There is right side lower limb paralysis, no when Clear and Bright sweeps a grave within 2014 suddenly in patient
Energy speech enters local hospital treatment then.Head CT shows " left side centrum ovale is shown in sheet depression density stove ", symptomatic treatment
Afterwards, still there are disfluency and right side lower limb that can not stand.After taking 2.5 courses for the treatment of of this drug, right lower extremity can voluntarily be careful, speech
Clearly, effective obvious.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 7: the Qin, male 68 years old, peasant.Patient's in January, 2016 is because there is left limb function barrier after quarreling with a neighbor
Hinder companion's unconsciousness to our hospital, is diagnosed as " right intracerebral hemorrhage in basal ganglia ".After emergency treatment row " extraventricular drainage art ", start to take
This drug, after taking 3.5 courses for the treatment of of this drug, patient's Consciousness, left limb can voluntarily be careful, other clinical symptoms are basic
It disappears, it is basic to cure.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 8: Ma, male, 49 years old, worker.In July, 2013, patient was surprisingly bereft of one's spouse, and mood is depressed always.For the year
Its children of night after entering the winter have found the unexpected astasia of Ma, are obnubilation after bed, are urinary and fecal inconvenience, examine in local hospital
Break as cerebral infarction.Routinize thrombolysis, nutrition cranial nerve etc. treatment after, patient's sanity, glossolalia, left side half body paralyse nothing
Method is stood.For further rehabilitation, start to take this drug, after taking 4 courses for the treatment of of this drug, can understand and link up, is voluntarily slow
Step, life can take care of oneself, basic to cure.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 9: Lyu, female, 73 years old, retired worker.In September, 2015, patient happen suddenly left limb powerlessly, suddenly at home
It falls down, glossolalia, the treatment of Sui Lai our hospital.MRI shows " right Basal ganglia half acute stage focus of infarct " that the thrombolysis that routinizes controls
After the treatment such as blood pressure, blood glucose, patient has replied mind, artistomia, but left limb dysfunction.It is controlled for further rehabilitation
It treats, after taking 3 courses for the treatment of of this drug, can walk on their own, take care of oneself, it is basic to cure.Effect of follow-up visit by telephone is without recurrence after half a year.
Case 10: it is neat certain, male, 56 years old, retired worker.It is diagnosed as " in brain before patient's readme 8 months in local county hospital
Wind " still has right side quadriplegia, is unable to independent ambulation, dizziness, the clear symptom of glossolalia after hospitalization.Take this drug 2.5
After a course for the treatment of, right side extremity numbness sense disappear can independent ambulation, understand without spinning sensation, verbal exposition, it is basic to cure.It is electric after half a year
Follow-up is talked about without recurrence.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, this field is common
Other modifications or equivalent replacement that technical staff makes technical solution of the present invention, without departing from technical solution of the present invention
Spirit and scope, be intended to be within the scope of the claims of the invention.
Claims (4)
1. a kind of preparation method for the Chinese herbal medicine for oral administration for treating headstroke, it is characterised in that: the following steps are included:
(1) various raw materials are weighed to crush, medicinal powder is prepared；
(2) above-mentioned medicinal powder is prepared into granule, pill or capsule；
It wherein takes Chinese herbal medicine orally to be made of the raw material of following parts by weight: 25 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis, 10 parts of peach kernel, safflower 15
Part, 7 parts of ramulus cinnamomi, 10 parts of Rhizoma Gastrodiae, 10 parts of radix achyranthis bidentatae, 15 parts of balsamine, 11 parts of uncaria, 7 parts of dragon's blood, 7 parts of pheretima, 6 parts of agkistrodon,
4 parts of centipede, 3 parts of leech, 4 parts of full worm and 10 parts of Radix Glycyrrhizae.
2. the preparation method of the Chinese herbal medicine for oral administration for the treatment of headstroke according to claim 1, it is characterised in that: the step
(2) pill in is prepared by the following steps:
(1) medicinal powder, fecula, distilled water are modulated into bolus, the bolus is prepared into molding pill；
(2) the molding pill is polished, the pill after being polished gets product pill after dry；
(3) the finished product pill is packed, obtains product.
3. the preparation method of the Chinese herbal medicine for oral administration for the treatment of headstroke according to claim 2, it is characterised in that: the bolus
Modulated process are as follows: take 60-100 parts of distilled water, be added fecula 20-40 parts, mild fire pours into container after being brewed into paste, then plus
Enter medicinal powder to stir evenly up to bolus.
4. the preparation method of the Chinese herbal medicine for oral administration for the treatment of headstroke according to claim 2, it is characterised in that: the step
(2) drying process in are as follows: the pill after the polishing is put into baking oven, the pill after polishing is dried at 50-70 DEG C
Water content < 10% is to get finished product pill.
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| CN1572314A (en) * | 2003-05-30 | 2005-02-02 | 咸阳步长医药科技发展有限公司 | Chinese patent medicine for treating apoplexy and its preparation method |
| CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
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| CN1572314A (en) * | 2003-05-30 | 2005-02-02 | 咸阳步长医药科技发展有限公司 | Chinese patent medicine for treating apoplexy and its preparation method |
| CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
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