CN106309672A - Gynecological lotion and preparation method thereof - Google Patents

Abstract

The invention relates to gynecological lotion and a preparation method thereof. The gynecological lotion is prepared from major active ingredients of common sage herb, and auxiliary ingredients of honeysuckle flowers, radix scutellariae, rhizoma coptidis, fructus forsythia, cortex phellodendri, herba menthae, borneol, pepper and fructus cnidii. The gynecological lotion is prepared from the following raw material ingredients in parts by mass: 50 to 70 parts of common sage herb, 1 to 5 parts of honeysuckle flowers, 1 to 4 parts of radix scutellariae, 1 to 3 parts of rhizoma coptidis, 1 to 5 parts of fructus forsythiae, 1 to 5 parts of cortex phellodendri, 1 to 7 parts of herba menthae, 1 to 5 parts of borneol, 1 to 8 parts of pepper and 1 to 5 parts of fructus cnidii. Various active ingredients are crushed, mixed and are dried, disinfected and crushed to be made into powdery materials with the fineness of about 200 meshes; 20g is used as one part; when the gynecological lotion is used, the ingredients are boiled for 15 minutes by boiling water or are soaked for 20 minutes by boiling water, then, steam generated by the medicine liquid is used for steaming the vulva when the steam is still hot; the medicine liquid is used for cleaning the vulva and the vagina after being slightly cooled.

Description

A kind of gynaecologic washing lotion and preparation method thereof

(1) technical field

The present invention relates to a kind of antibacterial-anti-inflammatory drug combination washing liquid, particularly a kind of with vegetable Chinese herbal medicine toad grass for the most former Drug regimen washing liquid for the treatment of gynecological inflammation class disease that material is made and preparation method thereof, belongs to field of Chinese herbal medicine technology.

(2) background technology

Toad grass, leaf surfaces is rough, as the skin of toad back, therefore obtains its name.Medicine name Herba Salviae Plebeiae, English name Claim Common Sage Herb.Another name: snow is shown in grass, elephant skin grass, toad grass, leprosy clam skin, wild mustard, Lai Zicao, Rana nigromaculata grass, snow In Folium Perillae blue or green, black, Herba Chenopodii, monkey back of the body grass, Radix Rubiae Yunnanensis, partridge chickens mother-in-law, ditch Herba Moslae, expand grass, pass the winter careless etc., various places call is not One.

Toad grass is born on hillside, roadside, wasteland, river bank wetland, height above sea level can be to 2800m.Main product Shandong, Jiangsu, Zhejiang River, Anhui, Sichuan, Hubei etc., in addition to Xinjiang, Gansu, Qinghai, Tibet, are almost distributed in the whole nation in all parts of the country overwhelming majority and save Part.Sowing time in autumn, in the summer, gathers time autumn, the flowers are in blossom, fringe is green to clean and dries or using fresh herb.At ordinary times can excavate at any time clean dry or Using fresh herb.Also can be transplanted to family Around the house can plant in case of need. also can receive seed and plant again.Main chemical compositions: contain Protocatechuic acid (protocatechuic acid), 4-hydroxyphenyl lactic acid, homoplantaginin (homoplantaginin), Buddhist nun moor flavone Glycoside (nepetrin), eupacunin (eupafolin), dinatin (hispidulin) etc..

Toad grass is as a herb, with all herbal medicine.Cool in nature, bitter in the mouth, pungent, have heat clearing away, detoxify, subside a swelling, removing heat from blood, Diuresis, dampness removing and the effect such as antipruritic, because its drug effect is notable, at the folk prescription being commonly used for curing the disease among the people, be mainly used in treating almond Body is scorching, hemoptysis of pulmonary tuberculosis, bronchitis, ascites swelling, oedema due to nephritis, metrorrhagia, have blood in stool, thrombocytopenic purpura；External is controlled The diseases such as doctor carbuncle, hemorrhoid, swelling and pain of anus, scalp itch, eczema, mastitis, vaginitis, tinea pedis.Cough there is specially good effect, to throat Swell and ache, chronic bronchitis has positive effect.

Existing using method among the people mainly has following several, and existing using method among the people mainly has following several, fills Divide and show that toad grass has good anti-inflammation effect and effect.

Using method one: be put in pot with decocting in water about 15 minutes with herb that is fresh or that dry, then with while hot with boiling The water of toad grass cleans or fumigates patient part, cures tinea pedis, carbuncle, hemorrhoid, swelling and pain of anus, eczema, breast in order to external The disease such as adenitis, vaginitis.

Using method two: the fresh and tender stem and leaf with toad grass is to boil water or brews up for treating tonsillitis, lung knot Core spitting of blood, bronchitis, ascites swelling, oedema due to nephritis, metrorrhagia, have blood in stool, the disease such as thrombocytopenic purpura.

Using method three: fry (decocting) egg with the fresh and tender stem and leaf of toad grass and take, cough is had specially good effect, to swelling throat Bitterly, chronic bronchitis has positive effect.

Although the toad this cheap Chinese herbal medicine evident in efficacy that is seen everywhere of grass is cured the disease among the people being widely used as Folk prescription, the most never cause national departments concerned and the enough attention of regular pharmacy corporation, developed the most widely And utilization.Though having use among the people, but most of ordinary people is the fewest to its cognition, the medical value of toad grass does not obtain To fully excavating and being widely used, during use, drug effect is not not fully exerted and utilizes, the range of toad grass Being not very extensive, using method is more original and single；The effective ingredient of medicine is not concentrated and is extracted, and does not has medicine The packaging changed and preparation, it is not very convenient for using, also not with other Chinese herbal medicine with the use of, form special for treating Plant unique Chinese medicinal components or the patent medicine of disease.A kind of low cost, determined curative effect, easy to use with toad grass it is Principle active component, adds other and assists effective ingredient in order to improve drug effect, be specifically used to treat in gynecological inflammation class disease What drug composition was made has the washing liquid of antibacterial and anti-inflammation functions, does not the most come out.

(3) summary of the invention

The present invention is in order to make up the deficiencies in the prior art, on the basis of folk prescription among the people, it is provided that a kind of with toad grass herb For principle active component, be equipped with other several have anti-inflammation, antiviral, heat clearing and damp drying, refrigerant, eliminating fire and detoxication effect its The Chinese medicinal components that its auxiliary active ingredient is made, various active drug composition synergism, it is used for improving curative effect, improves treatment effect Really, therapeutic process is shortened.Main active component is toad grass, and auxiliary active component is Flos Lonicerae, Radix Scutellariae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Rhizoma Coptidis, company Stick up, Cortex Phellodendri, Herba Menthae, Borneolum Syntheticum, Radix Glycyrrhizae, Pericarpium Zanthoxyli, Folium Artemisiae Argyi.The quality meter number of each raw material components is toad grass 50～70 parts, gold Flos Lonicerae 1～5 parts, Radix Scutellariae 1～4 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 1～6 parts, Rhizoma Coptidis 1～3 parts, Fructus Forsythiae 1～5 parts, Cortex Phellodendri 1～5 parts, Herba Menthae 1～7 parts, Borneolum Syntheticum 1～5 parts, Pericarpium Zanthoxyli 1～8 parts, Fructus Cnidii 1～5 parts.

The invention has the beneficial effects as follows, this Chinese medicinal components composition of raw material is simple, cheap, draws materials conveniently, processing system Making technique simple, product quality is easily controlled, patent medicine is cheap, carry with easy to use, have no side effect, anti-inflammation, Antiviral effect is obvious, determined curative effect, instant effect, short treating period；Contrast is used alone toad grass curative effect and becomes apparent from, and takes effect more Hurry up, the course for the treatment of is shorter.The washing liquid that this drug regimen boiling water is made after crossing or soaking with boiled water is permissible by cleaning disease sites It is specifically used to treat the inflammation class disease such as various types of tinea pedis and carbuncle, hemorrhoid, swelling and pain of anus, eczema, mastitis, vaginitis Sick.The method by cleaning that is especially suitable for treats the condyloma latum class pathological changes that various types of non-gonorrheas, syphilis and HPV virus cause With the inflammation class gynaecopathia of precancerosis modification, it is adapted to treat the cervicitis of simple type, vaginitis the most exactly, outward Cloudy pruritus, the gynaecopathia such as abnormal flavour of leucorrhea, an effective percentage 95%, four to six times is almost recovered, cure rate 80%, consolidates curative effect again Will not recur in a short time with three to five times, nonresponder should the Other diseases of examination in time.

(4) it is embodied as

The following is drug regimen of the present invention for treating a specific embodiment of gynecological inflammation class disease, main active component is Toad grass, auxiliary has other active component of anti-inflammation, antiviral, heat clearing and damp drying, eliminating fire and detoxication effect: Flos Lonicerae, Radix Scutellariae, Rhizoma Coptidis, Fructus Forsythiae, Cortex Phellodendri, Herba Menthae, Borneolum Syntheticum, Pericarpium Zanthoxyli and Fructus Cnidii.Based on the quality of each raw material components, number dispensing is as follows: Toad grass 60 parts, Flos Lonicerae 3 parts, Radix Scutellariae 3 parts, Rhizoma Coptidis 2 parts, Fructus Forsythiae 4 parts, Cortex Phellodendri 3 parts, Herba Menthae 6 parts, Borneolum Syntheticum 4 parts, Pericarpium Zanthoxyli 5 Part, Fructus Cnidii 5 parts.

After toad grass herb 60 parts is cut into the section of 1 centimeter length, the prepared slices of Chinese crude drugs with above-mentioned other medicines component mix And dry 2 hours in 120 degrees Celsius of bakers, disinfection by ultraviolet light 2 hours, further reinstate pulverizer and pulverize, make about 200 mesh thick Thin powder thing, then with every 20 grams for a, install sealing with small plastic bag, perform the labellings such as date, weight, title, It is positioned over the shady and cool lucifuge ventilation that is dried and stores stand-by.

Using method: a 20 grams of the powder made by this drug regimen is poured into totally without in the earth pot of greasy dirt, adds 1000 grams of boiled rear slow fire of clear water boil 15 minutes, or steep 20 minutes with 1000 grams of boiled water, then medicine and water one play into In clean special basin, the steam first produced with basin inner liquid medicine fumigates pudendum, after being somewhat cooled to less scald, then uses medicinal liquid Clean inside pudendum and vagina.

Can also stifling by this drug regimen and method and clean human body by the easily pathogenic bacterium such as fungus para-infectious other Disease sites, is used for treating the diseases such as carbuncle, hemorrhoid, swelling and pain of anus, anal inflammation, anal eczema, scalp itch, mastitis, tinea pedis.

The following is drug regimen gynaecologic washing lotion of the present invention for treating one group of concrete clinical trial of gynecological inflammation class disease Data, test site: select the big city Jinan City of the non-coastal non-wet thermal climate of central China.

Test season: summer 7, to August, compares how sultry wet weather, gynecological inflammation class disease suffering season.

Test crowd: gynecological inflammation class Disease 120 example, wherein vaginitis 40 example, pruritus vulvae 40 example, abnormal flavour of leucorrhea 40 examples；Age, 40 years old mean age, stablize relative with operating environment requirements of the living habit of testing crew was not 22 to 60 Very severe, working environment will not have the biggest change during testing, and the comparability of test data is higher, and the above persons are each It is divided into 6 groups, often organizes 20 people；

Trial drug: A group medicine uses the simple toad grass herb being dried to be cut into the section of 1 centimeter length, and B group medicine uses this A 20 grams of the drug regimen powder of invention；Two kinds of medicines by the boiled water boiling with soft fire 15 minutes of 1000g, are poured into clean simultaneously In basin standby.

Test method: first cleaned up by the pudendum of patient by warm water, removes secretions and dirt, uses above two medicine The steam of liquid is fumigated 10 minutes, until medicinal liquid not bery bathes one's feet in hot water, or else breaks and cleans V&V internal 20 minutes with medicinal liquid.Early Evening is each 6 days is once a course for the treatment of, and drug withdrawal is observed and within 3 days, carried out the next course for the treatment of again, altogether 2 courses for the treatment of of test, terminates each course for the treatment of After carry out effective evaluation.Prohibit the use of during treatment and take other medicine and Therapeutic Method, in order to avoid affecting this test Effect.

Test requirements document: wash the V&V inside of patient with medicinal liquid after, no longer by clean water, it is ensured that ill portion Position retains some ingredients, puts on underwear after drying again, and the same day, used medicinal liquid was used for soaking the underwear 30 points passed the same day Clock, afterwash dries.

Efficacy assessment standard:

1, invalid: and compare before treatment, symptom is not improved, or has and increase the weight of trend；

2, effective: and compare before treatment, symptom substantially alleviates；

3, recovery from illness: and compare before treatment, symptom is wholly absent.

Conclusion (of pressure testing): drug test process does not finds that the untoward reaction such as allergic symptom, test effect show that the present invention uses Safety, total effective rate 100%, contrast uses the simple toad grass herb being dried treatment cure rate higher, takes effect faster, right Vaginitis, pruritus vulvae, abnormal flavour of leucorrhea all have the highest cure rate.And a course for the treatment of basically reaches therapeutic effect.It is gynecological The active drug of inflammation class disease, has clinical value and promotional value.

Owing to the morbidity of gynecological inflammation class disease is mainly what antibacterial infection caused, self body constitution of patient, bad life It is accustomed to the particularly factor such as sexual life custom and used underwear, socks and all may cause palindromia, cure and be not equal to root Remove.So being likely to recurrence after Zhi Yuing, wanting to eradicate gynecological inflammation class disease and must form good clean living habit, especially It is sexual life custom, gives up unclean sexual life and the habit of multiple sex partner.

It addition, Lee the present inventor is wise and able suffers from tinea pedis and anal eczema for many years, annual summer all mild episode 3 to 5 times, Every time attack degree simply somewhat has the sensation scratched where it itches, as long as now timely using after drug regimen of the present invention cleans three to five times Just can fully recover, at ordinary times only it is noted that keep the sanitation and hygiene of foot and anus with dry, typically will not recur, even if recurrence is the most very Easily cure.Demonstrate the definite curative effect of drug regimen of the present invention in person.

Claims (2)

1. gynaecologic washing lotion and preparation method thereof, is characterized in that main active component is toad grass, and auxiliary active component is Flos Lonicerae, Radix Scutellariae, Rhizoma Coptidis, Fructus Forsythiae, Herba Menthae, Borneolum Syntheticum, Pericarpium Zanthoxyli, Fructus Cnidii；The quality meter number of each raw material components is toad grass 50～70 parts, Flos Lonicerae 1～5 parts, Radix Scutellariae 1～4 parts, Rhizoma Coptidis 1～3 parts, Fructus Forsythiae 1～5 parts, Cortex Phellodendri 1～5 parts, Herba Menthae 1～7 parts, Borneolum Syntheticum 1～5 parts, Pericarpium Zanthoxyli 1～8 parts, Fructus Cnidii 1～5 parts.

The most according to claim 1, a kind of gynaecologic washing lotion, is characterized in that its preparation method is that toad grass herb is cut into 1 li After the long section of rice with the prepared slices of Chinese crude drugs of above-mentioned other medicines component mixed be incorporated in 120 degrees Celsius of bakers in dry 2 hours, ultraviolet Line is sterilized 2 hours, further reinstates pulverizer and pulverizes, makes the powder thing of about 200 mesh thicknesses, then with every 20 grams for portion, Install sealing with small plastic bag, perform the labellings such as date, weight, title, be positioned over the shady and cool lucifuge ventilation that is dried and store stand-by； During use, a for the powder of this drug regimen 20 grams are poured into totally without in the earth pot of greasy dirt, add 1000 grams of clear water boiled after Slow fire boils 15 minutes, or steeps 20 minutes with 1000 grams of boiled water, then medicine and water one is played in clean basin, first uses basin Steam that inner liquid medicine produces is stifling has cleaned up pudendum, after being somewhat cooled to less scald, then with medicinal liquid clean pudendum and Vagina.