CN106306312A - Qi and blood benefiting pressed candy containing lactic acid bacteria and preparation method of pressed candy - Google Patents
Qi and blood benefiting pressed candy containing lactic acid bacteria and preparation method of pressed candy Download PDFInfo
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- CN106306312A CN106306312A CN201610759450.8A CN201610759450A CN106306312A CN 106306312 A CN106306312 A CN 106306312A CN 201610759450 A CN201610759450 A CN 201610759450A CN 106306312 A CN106306312 A CN 106306312A
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- powder
- lactic acid
- acid bacteria
- pressed candy
- blood
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title claims abstract description 222
- 241000894006 Bacteria Species 0.000 title claims abstract description 126
- 235000014655 lactic acid Nutrition 0.000 title claims abstract description 111
- 239000004310 lactic acid Substances 0.000 title claims abstract description 111
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 58
- 239000008280 blood Substances 0.000 title claims abstract description 45
- 210000004369 blood Anatomy 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title abstract description 20
- 239000000843 powder Substances 0.000 claims abstract description 165
- 239000000463 material Substances 0.000 claims abstract description 38
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 29
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 29
- 235000008434 ginseng Nutrition 0.000 claims abstract description 29
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 28
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims abstract description 27
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims abstract description 27
- 235000021014 blueberries Nutrition 0.000 claims abstract description 27
- 240000000851 Vaccinium corymbosum Species 0.000 claims abstract description 26
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 26
- 239000002994 raw material Substances 0.000 claims abstract description 19
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000008187 granular material Substances 0.000 claims abstract description 18
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 15
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 15
- 239000008103 glucose Substances 0.000 claims abstract description 15
- 239000008101 lactose Substances 0.000 claims abstract description 15
- 235000010352 sodium erythorbate Nutrition 0.000 claims abstract description 15
- 239000004320 sodium erythorbate Substances 0.000 claims abstract description 15
- RBWSWDPRDBEWCR-RKJRWTFHSA-N sodium;(2r)-2-[(2r)-3,4-dihydroxy-5-oxo-2h-furan-2-yl]-2-hydroxyethanolate Chemical compound [Na+].[O-]C[C@@H](O)[C@H]1OC(=O)C(O)=C1O RBWSWDPRDBEWCR-RKJRWTFHSA-N 0.000 claims abstract description 15
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 14
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 14
- 239000011718 vitamin C Substances 0.000 claims abstract description 14
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 13
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 13
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 13
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 13
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 11
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 11
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 11
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 11
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims abstract description 9
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 8
- 229940057948 magnesium stearate Drugs 0.000 claims abstract description 7
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 7
- 229960001866 silicon dioxide Drugs 0.000 claims abstract description 3
- 238000000034 method Methods 0.000 claims description 30
- 241000208340 Araliaceae Species 0.000 claims description 28
- 238000005469 granulation Methods 0.000 claims description 28
- 230000003179 granulation Effects 0.000 claims description 28
- 238000002156 mixing Methods 0.000 claims description 21
- 230000001476 alcoholic effect Effects 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 13
- 241000186660 Lactobacillus Species 0.000 claims description 10
- 229940039696 lactobacillus Drugs 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 9
- 239000007921 spray Substances 0.000 claims description 9
- 240000006024 Lactobacillus plantarum Species 0.000 claims description 7
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims description 7
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 7
- 229940072205 lactobacillus plantarum Drugs 0.000 claims description 7
- 244000199866 Lactobacillus casei Species 0.000 claims description 6
- 235000013958 Lactobacillus casei Nutrition 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 229940017800 lactobacillus casei Drugs 0.000 claims description 6
- 240000001046 Lactobacillus acidophilus Species 0.000 claims description 5
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims description 5
- 238000005453 pelletization Methods 0.000 claims description 5
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- -1 mixing Uniformly Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 14
- 238000003860 storage Methods 0.000 abstract description 4
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 230000002045 lasting effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 16
- 239000006041 probiotic Substances 0.000 description 10
- 230000000529 probiotic effect Effects 0.000 description 10
- 235000018291 probiotics Nutrition 0.000 description 10
- 230000000968 intestinal effect Effects 0.000 description 7
- 239000003094 microcapsule Substances 0.000 description 6
- 239000002671 adjuvant Substances 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 230000006870 function Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 241000790917 Dioxys <bee> Species 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 229910003978 SiClx Inorganic materials 0.000 description 3
- 230000009102 absorption Effects 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 210000000481 breast Anatomy 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 2
- 244000283207 Indigofera tinctoria Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 235000021028 berry Nutrition 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 108010013296 Sericins Proteins 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 244000077233 Vaccinium uliginosum Species 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 229940099352 cholate Drugs 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000008204 material by function Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/362—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
- A23G3/366—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
- A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides qi and blood benefiting pressed candy containing lactic acid bacteria and a preparation method of the pressed candy. The novel pressed candy containing the lactic acid bacteria and having advantages of good storage stability, safety, efficiency, lasting improvement and the effect of nourishing qi and blood of a human body is prepared through compounding from the following specific raw materials: lactic acid bacteria powder, glucose, maltodextrin, ginseng powder, Chinese angelica powder, red date powder, blueberry powder, 20.00% of lactose, vitamin C, sodium erythorbate, magnesium stearate, microcrystalline cellulose and silicon dioxide. Part of specific raw materials are granulated, then the granular materials are mixed with non-granulated powdery materials and are pressed, so that damage to the lactic acid bacteria in the preparation process is reduced greatly, and the number of live bacteria in the prepared qi and blood benefiting pressed candy containing the lactic acid bacteria is higher than or equal to 2.0*10<9>CFU/g.
Description
Technical field
The present invention relates to a kind of pressed candy, be specifically related to one and fill blood lactic acid bacteria pressed candy and preparation side thereof
Method, belongs to biotechnology and field of food.
Background technology
Lactic acid bacteria is a kind of probiotic bacteria being distributed widely in nature, because carbohydrate fermentation can become lactic acid obtain
Name.Lactic acid bacteria can improve nutritive value of food by the way of fermentation, improve flavour of food products, strengthens its keeping quality and additional
Value, physiologically active that additionally lactic acid bacteria is unique and trophic function, also can directly improve human body intestinal microbial population, strengthen intestinal motive force,
Loosening bowel to relieve constipation, help digest absorption, promote human immunity, be considered the medicine more safer than food, more more effective than medicine
Food.
Existing lactic acid bacteria tablet function is primarily present following defect: a kind, function singleness, plays the basic of health-care effect
Only lactic acid bacteria, mainly to intestinal beneficial；2, existing lactic acid bacteria tablet because of preparation method be by all raw materials through pelletize after tabletting
Obtaining, Lactobacillus loses after granulation, tabletting in a large number so that obtain viable lactic acid bacteria≤1.0*10 in lactic acid bacteria tablet7CFU/
G, its effect is extremely limited.3, the shelf-life is short, and when preserving during mainly showing as preserving, viable bacteria mortality rate is high thus affect effect.
Such as Application No. CN201410167563.X, entitled a kind of low-sugar probiotic bacterium pressed candy and preparation method thereof, by following heavy
The raw material composition of amount part: the live probiotic mycopowder 0.7 of lyophilizing～1.0 parts, Fructus actinidiae chinensis sarcocarp 10～15 parts, sericin peptide taken 1～3 parts,
Xylitol 20～30 parts, Herba Passiflorae Caeruleae sarcocarp 10～20 parts, defatted milk powder 20～40 parts, microcrystalline Cellulose 6～15 parts, tea powder 3～
10 parts, Polyethylene Glycol 0.5～1.5 parts；The preparation method of a kind of described low-sugar probiotic bacterium confection tabletting is provided simultaneously, mainly includes
(1) preparation of material；(2) mixing granulation；(3) tabletting.Therefore research worker is devoted to study how to improve breast in lactic acid bacteria tablet
The amount of acid bacterium viable count, is substantially at present and probiotic bacteria embedding is made microcapsule, such as Application No. CN201510217112.7
, entitled pressed candy containing probiotic microcapsule and preparation method thereof, described pressed candy be by probiotic microcapsule with
Confection adjuvant mixes, and uses dry granule tabletting to prepare.Described probiotic microcapsule is by lactic acid bacteria, functional materials and colloid
Aqueous solution solidification pelletize screening obtains.Probiotic bacteria is prefabricated into microcapsule by this, the most again with confection base material mixed pressuring plate, makes
Obtain its stability to improve, excellent to the toleration of human gastric juice and high cholate, can farthest send out hence into after human body
Wave effectiveness.The viable count of the method a certain degree of raising probiotic bacteria of energy, however it is necessary that and prepare microcapsule, add raw material and life
Produce cost.
Summary of the invention
Present invention seek to address that in prior art, lactic acid bacteria pressed candy health-care effect is single, in lactic acid bacteria tablet, viable count is relatively
Low (viable lactic acid bacteria≤1.0*107CFU/g) and lactic acid bacteria tablet shelf-life short problem, it is provided that one fills blood lactic acid bacteria tabletting
Confection, specifically by lactic acid bacteria mycopowder and red date powder, blue berry powder, Radix Ginseng powder, Radix Angelicae Sinensis powder and the specific collocation of each adjuvant, has manufactured one
Kind new storage stability is good, safely and effectively, persistently improve, have the lactic acid bacteria pressed candy of human body nourishing qi and blood effect.
Present invention also offers a kind of preparation method preparing the lactic acid bacteria pressed candy that fills blood, the method is different from tradition
Raw material tabletting after pelletizing is obtained, but the granule materials after specifically part material being pelletized again with the powder not have granulation
Tabletting after the material mixing of end, thus greatly reduce the preparation process damage to lactic acid bacteria, prepare viable count >=2.0*
109The lactic acid bacteria pressed candy that fills blood of CFU/g.
In order to solve above-mentioned technical problem, the present invention is achieved through the following technical solutions:
One fills blood lactic acid bacteria pressed candy, the following raw material including by mass percentage: lactic acid bacteria mycopowder 30.00～
40.00%, glucose 10.00～15.00%, maltodextrin 8.00%～15.00%, Radix Ginseng powder 7.00～9.00%, Radix Angelicae Sinensis powder 0.50
～1.50%, red date powder 0.30～0.70%, blue berry powder 0.30～0.70%, lactose 14.00～20.00%, vitamin C 0.20～
0.60%, sodium erythorbate 0.50～1.50%, magnesium stearate 0.50～1.50%, microcrystalline Cellulose 3.00～8.00%, dioxy
SiClx 6.00～12.00%.
Preferably, the viable count content of described lactic acid bacteria mycopowder is 2*1010～3*1010CFU/g。
Described lactic acid bacteria mycopowder is in Lactobacillus plantarum, bacillus acidophilus, lactobacillus casei and lactobacillus rhamnosus
Kind or two or more mixing.Lactobacillus plantarum mycopowder, bacillus acidophilus's mycopowder, lactobacillus casei mycopowder and Mus in the present invention
Lee's sugar lactobacillus mycopowder all can commercially buy acquisition.
Described lactic acid bacteria mycopowder, Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder were respectively what 100～120 mesh sieves obtained
Powder, i.e. fineness are at least 100～120 mesh.
A kind of method preparing the lactic acid bacteria pressed candy that fills blood, comprises the steps:
A, granulation
Granulation 1: glucose, lactose, sodium erythorbate, vitamin C are proportionally weighed rear mix homogeneously, uniformly sprays wine
Add granulator after essence solution to pelletize；
Granulation 2: after Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder being weighed in proportion, adds system after uniformly spraying alcoholic solution
Grain machine is pelletized；
It is dried: prepared particle drying is obtained granule materials；
B, powder process: weigh powder stock in proportion: lactic acid bacteria mycopowder, maltodextrin, magnesium stearate, microcrystalline Cellulose and dioxy
SiClx, mix homogeneously, obtain powder material；
C, mixing: the powder material mix homogeneously that granule materials step step A prepared and step B prepare, standby
With；
D, tabletting: mixed for step C material is taken out and carries out tabletting, obtain described in fill blood lactic acid bacteria pressed candy.
In step, in described granulation 1, spray body volume concentrations is the alcoholic solution of 40～60%, described alcoholic solution
Addition is glucose, lactose, sodium erythorbate and the 1.00 of vitamin C gross weight～5.00%；In described granulation 2, spray
Volumetric concentration is the alcoholic solution of 60～80%, and the consumption of described alcoholic solution is Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder and blue berry powder
The 15～35% of gross weight, the described sieve number used of pelletizing is 20 mesh.
In step, described being dried is to be dried 3～6h at 30～40 DEG C.
In stepb, described each powder stock is to cross the powder that 100～120 mesh sieves obtain respectively, i.e. fineness is at least 100
～120 mesh, in step C, described mixing is to mix 10～20min by rotating speed 10～30r/min in mixer.
In step D, humidity≤50% during described tabletting, temperature≤28 DEG C, pressure: 3.00～5.00kg/cm2。
Viable count of lactobacillus >=the 2.0*10 of the described lactic acid bacteria pressed candy that fills blood9CFU/g, moisture≤5.00%, tablet weight
0.25～1.00g/ grain.
The method have the advantages that
1. in proportioning raw materials:
The present invention first specifically by red date powder, blue berry powder, Radix Ginseng powder, Radix Angelicae Sinensis powder and lactic acid bacteria mycopowder and other adjuvants according to spy
Fixed proportioning combines, obtain a kind of new storage stability good, safely and effectively, persistently improve, have human body nourishing qi and blood make
Lactic acid bacteria pressed candy.
A, the effect of each component: the red date powder of interpolation, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder are all the works with nourishing qi and blood
Have with, lactic acid bacteria and directly improve the intestinal microbial population of human body, strengthen intestinal motive force, loosening bowel to relieve constipation, help digest absorptions, lifting human body
Effect of immunity, by lactic acid bacteria and red date powder, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder particular combination tabletting, is not only of value to
Intestinal can also the lactic acid bacteria confection of nourishing qi and blood, enrich the kind of lactic acid bacteria class health-care product, health-care effect on market.
Interaction between b, each component: lactic acid bacteria can improve gastrointestinal function, the metabolite energy that lactic acid bacteria produces
Enough promote that the functional component in red date powder, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder discharges, improve the absorption of functional component further
Rate.Therefore lactic acid bacteria and red date powder, blue berry powder, Radix Ginseng powder, Radix Angelicae Sinensis powder compound tabletting, and can not only play respective effect can also
Enough Synergistics, adjust intestinal microbial population at nourishing qi and blood simultaneously, it is ensured that healthy.
C, the function of product and technique effect: the present invention is by red date powder, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder and lactic acid
Mycopowder is aided with other adjuvant tablettings and becomes confection, imparts the new product form of red date powder, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder (pressure
Sheet confection), it is convenient for carrying and can eat at any time, just can absorb in red date powder, blue berry powder, Radix Ginseng powder and Radix Angelicae Sinensis powder time edible simultaneously
Plurality kinds of health care composition.
2, the technique effect of present invention process preparation method is as follows:
A, existing lactic acid bacteria product preservation the most difficult, moisture, air, temperature, nutrient, pressure etc. all can cause it
Dead.The viable lactic acid bacteria type product such as Yoghourt, mycopowder, the bacterium sheet etc. that now circulate all there are preservation defect.The inventive method is led to
Cross the selection to material and proportioning to control, it is achieved that the stability of tabletting low-loss and storage promotes, and lactic acid bacteria is at tableting processes
In loss be reduced to 20% from 80%, be greatly improved viable count content.
B, existing lactic acid bacteria sheeted product production technology by the powder containing viable count of lactobacillus and adjuvant mixing granulation
After, then granule is carried out tabletting, but pelletization can cause lactic acid bacteria damage and mortality inactivation, this has resulted in finally
Low (viable count≤the 1.0*10 of viable bacteria of product7CFU/g).Although powder stock tabletting can also directly be used, but directly adopt
With powder stock tabletting material fluidity is poor, tabletting is inefficient, it is unfavorable for that industrialization produces.The method of the present invention specifically will
Glucose, lactose, sodium erythorbate, vitamin C mixing granulation, by Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder mixing system
Grain, by maltodextrin, magnesium stearate, microcrystalline Cellulose and silicon dioxide powder process, the most again by prepared powder material and granule
Tabletting after material mixing, had both ensured ease for operation and the efficiency of compression molding, effectively reduced again the breast of the fide jussio indemnitatis to lactic acid bacteria
The survival rate of acid bacterium, has started a kind of brand-new lactic bacteria activity bacterium sheet mode of production, it is achieved that high viable count lactic acid bacteria tabletting
Confection, is suitable for industrialization and produces.
It is straight that maltodextrin, magnesium stearate, microcrystalline Cellulose and silicon dioxide powder process are achieved lactic acid bacteria mycopowder by the present invention
Tap into the purpose into tabletting link, it is to avoid the tabletting efficiency only lactic acid bacteria mycopowder powder process existed is low, outside the pressed candy obtained
See poor quality, problem that viable count of lactobacillus the is low.
C, be different from prior art lactic acid bacteria tabletting have to cold preservation, the present invention consists of specific raw material, proportioning
And the preparation method obtained that studies for a long period of time on the basis of raw material forms so that the lactic acid bacteria confection that fills blood of the present invention, can room temperature
Preserve and the room temperature shelf-life was up to 8 months (viable count >=2.0*10 in the shelf-life8Under refrigerated condition CFU/g), (temperature 4 DEG C～
6 DEG C) shelf-life is up to 24 months (viable count >=2.0*10 CFU/g in the shelf-life 8), exceed well over the lactic acid bacteria tablet of prior art
The stored refrigerated time.
Using volumetric concentration when d, the glucose of the present invention, lactose, sodium erythorbate, vitamin C mixing granulation is 40
～the alcoholic solution of 60%, when Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder are pelletized, the ethanol of employing volumetric concentration 60%～80% is molten
Liquid, i.e. can guarantee that two kinds of granule materials have excellent mouldability, it is ensured that the quality of granule materials, can reduce alcohol raw material simultaneously
Cost.
E, traditional tablet forming technique are in order to ensure the molding of product, and pressure is excessive, generally higher than 5.00kg/cm2, can't
Control the humiture of environment especially.But the humidity of the pressure of tabletting, environment and temperature is too high all can cause lactic acid bacteria survival rate
Reduction, therefore raw material by material choice, burden control and is respectively prepared powder and granule by the present invention, so that the present invention
The lactic acid bacteria pressed candy that fills blood can be at tabletting humidity≤50%, temperature≤28 DEG C, pressure: 3.00～5.00kg/cm2Bar
Part lower sheeting molding, this tabletting conditions can reduce lactic acid bacteria loss in the tabletting course of processing.
In sum, the present invention uses the processing mode of grain+grain+powder, and by controlling processing environment condition such as temperature, pressure
Power etc., on the one hand solve effective configuration of production efficiency and functional effect (viable count and health care), meet the product holding time
Under conditions of length, conscientiously accomplish to reduce cost；On the other hand by starting components, preparation technology and the adjustment of control parameter
Guarantee to realize foregoing invention purpose.
Detailed description of the invention
The present invention is described in detail below in conjunction with specific embodiment.
The raw materials used conventional raw material being commercially of the present invention.
Embodiment 1
The present embodiment 1 is as a example by the lactic acid bacteria pressed candy that fills blood producing 1kg.
One fills blood lactic acid bacteria pressed candy, is made up of the following raw material weighed by quality: lactic acid bacteria mycopowder
300.00g, glucose 150.00g, maltodextrin 150.00g, Radix Ginseng powder 70.00g, Radix Angelicae Sinensis powder 5.00g, red date powder 3.00g, indigo plant
Certain kind of berries powder 3.00g, lactose 200.00g, vitamin 4.00g, sodium erythorbate 10.00g, magnesium stearate 5.00g, microcrystalline Cellulose
40.00g, silicon dioxide 60.00g.
Embodiment 2
The present embodiment is as a example by the lactic acid bacteria pressed candy that fills blood producing 50kg.
One fills blood lactic acid bacteria pressed candy, is made up of the following raw material weighed by quality: lactic acid bacteria mycopowder
17.50kg, glucose 5.00kg, maltodextrin 5.00kg, Radix Ginseng powder 4.50kg, Radix Angelicae Sinensis powder 0.75kg, red date powder 0.35kg, indigo plant
Certain kind of berries powder 0.35kg, lactose 7.00kg, vitamin C 0.30kg, sodium erythorbate 0.75kg, magnesium stearate 0.75kg, crystallite are fine
Dimension element 2.45kg, silicon dioxide 4.50kg(9%).
Embodiment 3
The present embodiment is as a example by the production of 100kg lactic acid bacteria pressed candy.
One fills blood lactic acid bacteria pressed candy, is made up of the following raw material weighed by quality: lactic acid bacteria mycopowder
40.00kg, glucose 11.00kg, maltodextrin 8.00kg, Radix Ginseng powder 8.00kg, Radix Angelicae Sinensis powder 1.00kg, red date powder 0.50kg,
Blue berry powder 0.50kg, lactose 16.80kg, vitamin C 0.20kg, sodium erythorbate 0.50kg, magnesium stearate 0.50kg, crystallite
Cellulose 3.00kg, silica 1 0.00kg.
Embodiment 4
The present embodiment is as a example by the lactic acid bacteria pressed candy that fills blood producing 500kg.
One fills blood lactic acid bacteria pressed candy, is made up of the following raw material weighed by quality: lactic acid bacteria mycopowder 160kg,
Glucose 65kg, maltodextrin 42.5kg, Radix Ginseng powder 30 kg, Radix Angelicae Sinensis powder 10kg, red date powder 25kg, blue berry powder 25kg, lactose
75kg, vitamin C 1kg, sodium erythorbate 2.5kg, magnesium stearate 2.5kg, microcrystalline Cellulose 1.5kg, silicon dioxide 60kg.
Embodiment 5
The present embodiment is on the basis of embodiment 1～4 any embodiment:
Preferably, the viable count content of the described lactic acid bacteria mycopowder of the present embodiment is 2*1010CFU/g.Described lactic acid bacteria mycopowder is excellent
Elected the powder that 100 mesh sieves obtain as.
The described lactic acid bacteria mycopowder of the present embodiment is Lactobacillus plantarum mycopowder.
The Radix Ginseng powder of the present embodiment, Radix Angelicae Sinensis powder, red date powder, blue berry powder are preferably and cross the powder that 100 mesh sieves obtain respectively.
Embodiment 6
The present embodiment is on the basis of embodiment 1～4 any embodiment:
Preferably, the viable count content of the described lactic acid bacteria mycopowder of the present embodiment is 2.5*1010CFU/g.Described lactic acid bacteria mycopowder
It was preferably the powder that 110 mesh sieves obtain.
The described lactic acid bacteria mycopowder of the present embodiment is Lactobacillus plantarum, the mixing mycopowder of bacillus acidophilus two kinds.
The Radix Ginseng powder of the present embodiment, Radix Angelicae Sinensis powder, red date powder, blue berry powder are preferably and cross the powder that 110 mesh sieves obtain respectively.
Embodiment 7
The present embodiment is on the basis of embodiment 1～4 any embodiment:
Preferably, the viable count content of the described lactic acid bacteria mycopowder of the present embodiment is 3*1010CFU/g.Described lactic acid bacteria mycopowder is excellent
Elected the powder that 120 mesh sieves obtain as.
The described lactic acid bacteria mycopowder of the present embodiment is Lactobacillus plantarum, bacillus acidophilus, lactobacillus casei and rhamnose breast
The mixing mycopowder of bacillus.
The Radix Ginseng powder of the present embodiment, Radix Angelicae Sinensis powder, red date powder, blue berry powder are preferably the powder obtained for mistake 120 mesh sieves the most respectively.
Embodiment 8
The present embodiment provides a kind of method of lactic acid bacteria pressed candy that fills blood preparing embodiment 1～7 any embodiment, this bag
Include following step:
A, granulation
Granulation 1: glucose, lactose, sodium erythorbate, vitamin C are proportionally weighed rear mix homogeneously, uniformly sprays wine
Add granulator after essence solution to pelletize；
Granulation 2: after Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder being weighed in proportion, adds system after uniformly spraying alcoholic solution
Grain machine is pelletized；
It is dried: prepared particle drying is obtained granule materials；
The described sieve number used of pelletizing is 20 mesh, and i.e. obtained granule needs the screen cloth through 20 mesh.
B, powder process: weigh powder stock in proportion: lactic acid bacteria mycopowder, maltodextrin, magnesium stearate, microcrystalline Cellulose and
Silicon dioxide, mix homogeneously, obtain powder material；
C, mixing: the powder material mix homogeneously that granule materials step step A prepared and step B prepare, standby
With；
D, tabletting: mixed for step C material is taken out and carries out tabletting, obtain described in fill blood lactic acid bacteria pressed candy.
Producing the finished product index obtained as stated above is: viable count of lactobacillus >=2.0*109CFU/g, moisture≤
5.00%, tablet weight 0.25～1.00g/ grain.
In the present embodiment, lactic acid bacteria mycopowder uses Lactobacillus plantarum, lactobacillus casei and the mixed vaccine of lactobacillus rhamnosus
Powder.
Embodiment 9
The present embodiment further provides the method for the lactic acid bacteria pressed candy that fills blood of preparation embodiment 1:
A, granulation
Granulation 1: glucose, lactose, sodium erythorbate, vitamin C are proportionally weighed rear mix homogeneously, uniformly sprays dense
Degree is for 40.00%(V/V) alcoholic solution 1.00%(G/G) then add granulator and enter to pelletize；The granule prepared crosses 20 mesh sieves；
Granulation 2: after Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder being weighed in proportion, uniform spray concentration is 80%(V/V)
Alcoholic solution 35.00%(G/G) afterwards add granulator pelletize；The granule prepared crosses 20 mesh sieves；
It is dried: being dried is to be dried 6h in 30 DEG C of drying baker；
B, powder process: weigh powder stock in proportion: lactic acid bacteria mycopowder, maltodextrin, magnesium stearate, microcrystalline Cellulose and dioxy
SiClx, mix homogeneously, obtain powder material；Described each powder stock is to cross the powder that 100 mesh sieves obtain respectively；
C, mixing: the powder material that granule materials step step A prepared and step B prepare sends into mixer,
Under the conditions of 10r/min, mix 20min, obtain tabletting mixed material, standby；
D, tabletting: mixed for step C material is taken out at ambient temperature 24 DEG C, humidity 25%, pressure 3.00kg/cm2Under the conditions of
Tabletting, obtaining bacterium tablet quality is 0.33g/ grain, and smooth surface is without the lactic acid bacteria pressed candy that fills blood of dry linting phenomenon.According to
GB4789.3 carries out viable count of lactobacillus detection, and its viable count is: 2.4*109CFU/g。
In the present embodiment, lactic acid bacteria mycopowder uses lactobacillus casei and the mixing mycopowder of lactobacillus rhamnosus.
Embodiment 10
The present embodiment further provides the method for the lactic acid bacteria pressed candy that fills blood of preparation embodiment 2:
The present embodiment is with the difference of the preparation method of embodiment 9: in the present embodiment, in step, adds in described granulation 1
Adding concentration is 50%(V/V) alcoholic solution 3.5%(G/G), in described granulation 2 add concentration be 65%(V/V) alcoholic solution
25%(G/G)；Described being dried is to be dried 4.5h in 35 DEG C of drying baker；In the present embodiment, in stepb, described each powder is former
Material is for crossing the powder that obtains of 110 mesh sieves respectively, and in step C, granulation material and powder material are in mixing condition 20r/ of mixer
Min, 15min；The tabletting conditions of the present embodiment is ambient temperature 25 DEG C, humidity 40%, pressure 4.00kg/cm2, obtain bacterium sheet matter
Amount is 0.67g/ grain, and smooth surface is without dry linting phenomenon.Carrying out viable count of lactobacillus detection according to GB4789.3, its viable count is:
2.6*109CFU/g。
Embodiment 11
The present embodiment further provides the method for the lactic acid bacteria pressed candy that fills blood of preparation embodiment 3:
The present embodiment method is with the difference of the preparation method of embodiment 9: in the present embodiment, in step, and described granulation 1
Middle interpolation concentration is 60%(V/V) alcoholic solution 5%(G/G), in described granulation 2 add concentration be 60%(V/V) alcoholic solution
15%(G/G)；Described being dried is to be dried 3h in 40 DEG C of drying baker；In the present embodiment, in stepb, described each powder stock is
Cross the powder that 120 mesh sieves obtain respectively, in step C, granulation material and powder material in mixing condition 30r/min of mixer,
10min；The tabletting conditions of the present embodiment is ambient temperature 26 DEG C, humidity 50%, pressure 5.00kg/cm2, obtaining bacterium tablet quality is
0.76g/ grain, smooth surface is without dry linting phenomenon.Carrying out viable count of lactobacillus detection according to GB4789.3, its viable count is: 3.3*
109CFU/g。
Claims (10)
1. the lactic acid bacteria pressed candy that fills blood, it is characterised in that: include following raw material by mass percentage: lactic acid bacteria
Mycopowder 30.00～40.00%, glucose 10.00～15.00%, maltodextrin 8.00%～15.00%, Radix Ginseng powder 7.00～
9.00%, Radix Angelicae Sinensis powder 0.50～1.50%, red date powder 0.30～0.70%, blue berry powder 0.30～0.70%, lactose 14.00～
20.00%, vitamin C 0.20～0.60%, sodium erythorbate 0.50～1.50%, magnesium stearate 0.50～1.50%, crystallite are fine
Dimension element 3.00～8.00%, silicon dioxide 6.00～12.00%.
One the most according to claim 1 fills blood lactic acid bacteria pressed candy, it is characterised in that: described lactic acid bacteria mycopowder
Viable count content is 2*1010～3*1010CFU/g, described lactic acid bacteria mycopowder was the powder that 100～120 mesh sieves obtain.
One the most according to claim 1 fills blood lactic acid bacteria pressed candy, it is characterised in that: described lactic acid bacteria mycopowder bag
Include a kind of or the most two or more mixing in Lactobacillus plantarum, bacillus acidophilus, lactobacillus casei and lactobacillus rhamnosus.
One the most according to claim 1 fills blood lactic acid bacteria pressed candy, it is characterised in that: described Radix Ginseng powder, Radix Angelicae Sinensis
Powder, red date powder, blue berry powder were respectively the powder that 100～120 mesh sieves obtain.
5. the method preparing the lactic acid bacteria pressed candy that fills blood as claimed in claim 1, it is characterised in that: include following step
Rapid:
A, granulation
Granulation 1: glucose, lactose, sodium erythorbate, vitamin C are proportionally weighed rear mix homogeneously, uniformly sprays wine
Add granulator after essence solution to pelletize；
Granulation 2: after Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder, blue berry powder being weighed in proportion, adds system after uniformly spraying alcoholic solution
Grain machine is pelletized；
It is dried: prepared particle drying is obtained granule materials；
B, powder process:
Weigh powder stock in proportion: lactic acid bacteria mycopowder, maltodextrin, magnesium stearate, microcrystalline Cellulose and silicon dioxide, mixing
Uniformly, powder material is obtained；
C, mixing
The powder material mix homogeneously that granule materials step step A prepared and B prepare, standby；
D, tabletting: mixed for step C material is taken out and carries out tabletting, obtain described in fill blood lactic acid bacteria pressed candy.
A kind of method preparing the lactic acid bacteria pressed candy that fills blood the most according to claim 5, it is characterised in that: in step
In A, in described granulation 1, spray body volume concentrations is the alcoholic solution of 40～60%, the addition of described alcoholic solution be glucose,
Lactose, sodium erythorbate and the 1.00 of vitamin C gross weight～5.00%；In described granulation 2, spray body volume concentrations be 60～
The alcoholic solution of 80%, the consumption of described alcoholic solution be Radix Ginseng powder, Radix Angelicae Sinensis powder, red date powder and the 15 of blue berry powder gross weight～
35%；The described sieve number used of pelletizing is 20 mesh.
A kind of method preparing the lactic acid bacteria pressed candy that fills blood the most according to claim 5, it is characterised in that: in step
In A, described being dried is to be dried 3～6h at 30～40 DEG C.
A kind of method preparing the lactic acid bacteria pressed candy that fills blood the most according to claim 5, it is characterised in that: in step
In B, described each powder stock is to cross the powder that 100～120 mesh sieves obtain respectively, and in step C, described mixing is in mixer
10～20min are mixed by rotating speed 10～30r/min.
A kind of method preparing the lactic acid bacteria pressed candy that fills blood the most according to claim 5, it is characterised in that: in step
In D, humidity≤50% during described tabletting, temperature≤28 DEG C, pressure: 3.00～5.00kg/cm2。
A kind of method preparing the lactic acid bacteria pressed candy that fills blood the most according to claim 5, it is characterised in that: described benefit
Viable count of lactobacillus >=the 2.0*10 of QI and blood lactic acid bacteria pressed candy9CFU/g, moisture≤5.00%, tablet weight 0.25～1.00g/ grain.
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| CN110301515A (en) * | 2019-07-16 | 2019-10-08 | 吉林农业大学 | A kind of ginseng blueberry pressed candy of high added value and preparation method thereof |
| CN114027431A (en) * | 2021-11-12 | 2022-02-11 | 广州市广马医药科技有限公司 | Probiotic solid beverage with effects of enriching blood and promoting bowel circulation |
| CN114762511A (en) * | 2021-01-11 | 2022-07-19 | 陈志宏 | Buccal tablet prepared by mixing forest berries and ginseng |
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Application publication date: 20170111 |
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| RJ01 | Rejection of invention patent application after publication |