CN106267002A - A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof - Google Patents

Abstract

nullThe invention belongs to technical field of Chinese medicine，Purpose is a kind of Chinese medicine composition treating rheumatoid arthritis according to the traditional Chinese medical science, rheumatoid arthritis being recognized mechanism and providing，Each component of described Chinese medicine composition and mass parts ratio thereof are as follows: Herba Ephedrae 1.5～12g、Radix Clematidis 10～16g、Os pardi 15～30g、Radix Achyranthis Bidentatae 5～15g、Radix Angelicae Pubescentis 3～15g、The Cortex Eucommiae 6～16g、Rhizoma Gastrodiae 3～12g、Fructus Corni (enucleation) 6～12g、Bar halberd 6～18g、Radix Gentianae Macrophyllae 3～10g、Stigma Croci 1.5～4.5g、Fructus Alpiniae Oxyphyllae 3～12g、Rhizoma Chuanxiong 3～12g、Scorpio 3～5g、Carapax et Plastrum Testudinis 15～40g、Radix Notoginseng 3～11g、Radix Saposhnikoviae 8～18g、Rhizoma Corydalis 3～10g、Radix Angelicae Sinensis 8～16g、Radix Curcumae 3～12g、Rhizoma Cibotii 3～15g、Radix Glycyrrhizae 2.5～15g；The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition treating rheumatoid arthritis, Particularly for the field of Chinese medicine composition and preparation method thereof of patient with rheumatoid arthritis.

Background technology

Rheumatoid arthritis is a kind of chronic systemic autoimmune disease based on arthropathy.Major Clinical table The now arthralgia caused by Minor articulus synovial membrane, cartilage destruction, joint space narrow then, and late period is because of serious bone destruction, suction Receipts cause joint stiffness, deformity, dysfunction.Prevalence in China's rheumatoid arthritis is 0.24-0.5%, and women is more than Male, about 2-3:1, any age all can fall ill, most with 20-50 year.Primary disease mostly is a kind of repeated relapsing disease, disability rate Higher, prognosis mala, for now, does not effects a radical cure medicine or the method for above-mentioned disease the most very well.

So, just how to find a kind of medicine that can effectively treat rheumatoid arthritis, be that we are badly in need of solving at present Problem certainly.

Summary of the invention

Along with the development of China's Chinese medicine, in treatment rheumatoid arthritis, people gradually appreciate The advantage of the above-mentioned rheumatoid arthritis of Chinese traditional treatment, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, for existing There is the present situation of the above-mentioned rheumatoid arthritis of western medical treatment, it is an object of the invention to be to provide one to treat rheumatoid joint Scorching Chinese medicine composition, to solve the most restorative problem of patient with rheumatoid arthritis.This medicine is with in common Medicine is raw material, has instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned rheumatoid arthritis.

For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provides one to treat rheumatoid and closes Chinese medicine composition that joint is scorching and preparation method thereof, it is characterised in that each component of described Chinese medicine composition and mass parts are such as Shown in lower:

Herba Ephedrae 1.5～12g, Radix Clematidis 10～16g, Os pardi 15～30g, Radix Achyranthis Bidentatae 5～15g, Radix Angelicae Pubescentis 3～15g, the Cortex Eucommiae 6～ 16g, Rhizoma Gastrodiae 3～12g, Fructus Corni (enucleation) 6～12g, bar halberd 6～18g, Radix Gentianae Macrophyllae 3～10g, Stigma Croci 1.5～4.5g, Fructus Alpiniae Oxyphyllae Core 3～12g, Rhizoma Chuanxiong 3～12g, Scorpio 3～5g, Carapax et Plastrum Testudinis 15～40g, Radix Notoginseng 3～11g, Radix Saposhnikoviae 8～18g, Rhizoma Corydalis 3～10g, when Return 8～16g, Radix Curcumae 3～12g, Rhizoma Cibotii 3～15g, Radix Glycyrrhizae 2.5～15g.

A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof, it is characterised in that described Chinese drug-treated group Each component of compound and mass parts ratio are as follows:

Herba Ephedrae 8～11g, Radix Clematidis 11～14g, Os pardi 20～26g, Radix Achyranthis Bidentatae 8～13g, Radix Angelicae Pubescentis 8～13g, the Cortex Eucommiae 8～14g, Rhizoma Gastrodiae 6～11g, Fructus Corni (enucleation) 8～11g, bar halberd 10～16g, Radix Gentianae Macrophyllae 6～9g, Stigma Croci 2～4.2g, Fructus Alpiniae Oxyphyllae 6～ 11g, Rhizoma Chuanxiong 6～11g, Scorpio 3.5～4.5g, Carapax et Plastrum Testudinis 20～35g, Radix Notoginseng 6～10g, Radix Saposhnikoviae 10～16g, Rhizoma Corydalis 6～9g, when Return 10～14g, Radix Curcumae 6～11g, Rhizoma Cibotii 8～13g, Radix Glycyrrhizae 6～13g.

A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof, it is characterised in that described " the most square Case " each component of Chinese medicine composition and mass parts ratio as follows:

Herba Ephedrae 10g, Radix Clematidis 13g, Os pardi 23g, Radix Achyranthis Bidentatae 12g, Radix Angelicae Pubescentis 12g, Cortex Eucommiae 13g, Rhizoma Gastrodiae 10g, Fructus Corni (enucleation) 10g, bar halberd 14g, Radix Gentianae Macrophyllae 8g, Stigma Croci 4g, Fructus Alpiniae Oxyphyllae 10g, Rhizoma Chuanxiong 10g, Scorpio 4g, Carapax et Plastrum Testudinis 30g, Radix Notoginseng 9g, Radix Saposhnikoviae 14g, Rhizoma Corydalis 8g, Radix Angelicae Sinensis 13g, Radix Curcumae 10g, Rhizoma Cibotii 12g, Radix Glycyrrhizae 12g.

A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof, it is characterised in that described method bag Include following steps to be prepared from:

A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be ground into superfine end according to mass parts ratio stand-by；

B, the method preparing Chinese medicine capsules according to tradition, after being sieved by ground superfine myrrh thing, put in medicine device and mix Uniformly, capsule (the sealed rear total length of its capsule is 23.3mm, medicated powder capacity 0.4～0.5g/ grain), and then subpackage then it are prepared as Seal standby.

A kind of Chinese medicine composition treating rheumatoid arthritis and preparation method thereof, it is characterised in that described in the side of taking Method is: by the capsule medicine prepared to take three times a day, the morning, noon and afternoon service once, dosage 2g/time, taking medicine before meal, clothes Medicine 15～60 days, symptom substantially alleviates or fully recovers.

Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:

Herba Ephedrae, nature and flavor: hardship pungent, micro-, warm in nature, there is effect of relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema, be used for treating wind and cold Exterior excess syndrome, fever with aversion to cold, lossless, headache body pain, heresy stops up in lung, inhibited pulmonary QI, cough and asthma, edema caused by wind, dysuria, rheumatism Arthralgia pain, numbness of the skin and rubella pruritus, carbuncle of yin nature sucutaneous nodule；

Radix Clematidis, nature and flavor: acrid in the mouth, hardship salty, micro-, warm in nature, mild toxicity, there is effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, be used for treating wind Pain of dampness syndrome, numb limbs and tense tendons, muscle arteries and veins contracture, joint stuffiness, tinea pedis swells and ache, malaria, bone choke with sobs larynx, and controls the diseases such as phlegm retention accumulation；

Os pardi, nature and flavor: acrid in the mouth, salty, warm in nature, there is effect of wind-damp dispelling, bone and muscle strengthening, tranquillizing the mind by relieving convulsion, be used for treating anemofrigid-damp arthralgia, Bones and muscles pain, spasm of the limbs are numb, waist knee joint is miserable, infantile convulsion is twitched；

Radix Achyranthis Bidentatae, nature and flavor: sweet in the mouth, hardship, acid, property are put down, and have effect of dissipating blood stasis blood, subduing inflammation, are used for treating soreness of waist and knee joint, lower limb Flaccidity is soft, amenorrhea due to stagnation of blood, dysmenorrhea, abdominal pain due to blood stasis in puerperal, note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, pharynx Larynx swells and ache；

Radix Angelicae Pubescentis, nature and flavor: pungent, bitter, tepor, there is effect of expelling wind and removing dampness, numbness relieving and pain relieving, be used for treating anemofrigid-damp arthralgia, waist knee joint pain Bitterly, few the moon volt wind headache；

The Cortex Eucommiae, nature and flavor: sweet, micro-pungent, warm in nature, there is invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect, be used for treating spinal column ache, sun Flaccidity, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion；

Rhizoma Gastrodiae, nature and flavor: sweet, pungent, flat, nontoxic, there is endogenous wind stopping relieving convulsion, suppressing the hyperactive liver sun, effect of dispelling wind and removing obstruction in the collateral, be used for treating anxious intermittent infantile convulsion Wind, tic contracture, dizziness, headache, hemiplegia, limb fiber crops, rheumatic arthralgia；

Fructus Corni (enucleation), nature and flavor: sour, puckery, tepor, there is effect of liver and kidney tonifying, essence astringing and desertion stemming, be used for treating dizziness ear Ring, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat are quenched one's thirst, additionally, this product can be consolidated again through only Blood, can use and control the diseases such as human female void, menorrhagia；

Ba Ji, nature and flavor: Xin Gan, temperature, there is effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness, be used for treating impotence due to deficiency of the kidney, Seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb are infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism limb gas；

Radix Gentianae Macrophyllae, nature and flavor: pungent, bitter, flat, there is effect of wind-damp dispelling, clearing away damp-heat, stopping numbness pain, be used for treating rheumatic arthralgia, muscle arteries and veins is arrested Contraction, joint are ached, the heating of afternoon fever, infantile malnutrition；

Stigma Croci, nature and flavor: sweet in the mouth, property are flat, have effect of blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving, be used for treating troubled thoughts pent-up, Chest and diaphragm painful abdominal mass is vexed, spit blood, typhoid fever is gone mad, frightened be afraid of in a trance, women's amenorrhea, stasis menoxenia, prolonged lochia, blood stasis are had a pain, Measles, traumatic injury etc.；

Fructus Alpiniae Oxyphyllae, nature and flavor: acrid in the mouth, warm in nature, have and warming spleen and stopping diarrha take the photograph saliva, effect of warming the kidney reducing urination controlling nocturnal emission with astringent drugs, be used for treating taste empty Tremble with fear, vomit, have loose bowels, cold in abdomen educate, the many salivas of mouth, enuresis due to deficiency of the kidney, frequent micturition, seminal emission, the disease such as nebulousurine；

Rhizoma Chuanxiong, nature and flavor: pungent, warm, there is effect of blood-activating and qi-promoting, wind-expelling pain-stopping, for treatment pacify nerve, positive wind syndrome of head headache, Lump in the abdomen stomachache, the breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia；

Scorpio, nature and flavor: pungent, flat, poisonous, there is effect of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, be used for treating children's and shy Wind, tic spasm, middle air port are askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula；

Carapax et Plastrum Testudinis, nature and flavor: salty sweet, flat, there is YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, effect of strong bone, control deficiency of kidney yin, hectic fever due to YIN-deficiency labor for treatment Heat, haematemesis, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, children's's fontanel are not The diseases such as conjunction；

Radix Notoginseng, nature and flavor: hardship sweet, micro-, temperature, there is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain, be used for treating spitting of blood, haematemesis, epistaxis, Have blood in stool, the disease such as metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling；

Radix Saposhnikoviae, nature and flavor: acrid in the mouth, sweet, slightly warm in nature, there is expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic effect, be used for treating Affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache is had loose bowels, at the beginning of discharging fresh blood stool, tetanus, rubella pruritus, skin infection Rise etc. disease；

Rhizoma Corydalis, nature and flavor: bitter, micro-pungent, warm, have invigorate blood circulation, promoting the circulation of QI, effect of pain relieving, be used for treating stomachache, chest and hypochondrium, stomachache, sudden and violent Lumbago, colic, dysmenorrhea, abdominal pain due to blood stasis in puerperal, abdominal mass, traumatic injury, now be used for treating coronary heart disease, arrhythmia；

Radix Angelicae Sinensis, nature and flavor: sweet in the mouth, hardship pungent, micro-, warm in nature, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, be used for treating Menoxenia, amenorrhea stomachache, abdominal mass tie poly-, metrorrhagia;Headache due to deficiency of blood, dizziness, flaccidity syndrome and arthralgia syndrome, weight, carbuncle skin ulcer after dryness of the intestine dyschezia, bloody dysentery Surreptitiously, injury from falling down；

Radix Curcumae, nature and flavor: acrid in the mouth, hardship, cold in nature, have invigorate blood circulation only can, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, effect of depressed liver-energy dispersing and function of gallbladder promoting, be used for The treatment chest and abdomen side of body all pains of rib, dysmenorrhes, amenorrhea, abdominal mass caking, calentura coma, demented, infantile convulsion, spit blood, be defeated in battle standby, stranguria with blood, sand Pouring, jaundice；

Rhizoma Cibotii, nature and flavor: bitter, sweet, warm, have except rheumatism, strong waist foot, the effect in profit joint, be used for treating lumbago due to renal deficiency ridge strong, sufficient The diseases such as knee joint weakness, rheumatic arthralgia, frequent micturition, seminal emission, leukorrhagia；

Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, use In treatment asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, extremity contraction urgency pain, hysteria, cough and asthma, swelling throat Bitterly, ulcerative carbuncle swell and ache, infantile carbuncle and the disease such as medicine, alimentary toxicosis.

Medicine of the present invention is differential diagnosis of diseases based on Rheumatoid Arthritis with Traditional Chinese Medicine and the dialectical principle combined, from pharmacology Effect and mechanism of action are thought: with regard to rheumatoid arthritis one disease, each raw material herbal medicine efficacy in medicine provided by the present invention Play altogether, above-mentioned disease is had good therapeutic effect.

Detailed description of the invention

The present invention is aiming at the treatment of above-mentioned rheumatoid arthritis and a kind of Chinese medicine formula of proposing, uses this formula The medicine effect of preparation is good, and instant effect is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Below in conjunction with this The detailed description of the invention of invention is described in further detail:

Embodiment 1:

A kind of Chinese medicine composition treating rheumatoid arthritis, it is characterised in that each component of described Chinese medicine composition and Mass parts ratio is as follows:

Herba Ephedrae 10g, Radix Clematidis 13g, Os pardi 23g, Radix Achyranthis Bidentatae 12g, Radix Angelicae Pubescentis 12g, Cortex Eucommiae 13g, Rhizoma Gastrodiae 10g, Fructus Corni (enucleation) 10g, bar halberd 14g, Radix Gentianae Macrophyllae 8g, Stigma Croci 4g, Fructus Alpiniae Oxyphyllae 10g, Rhizoma Chuanxiong 10g, Scorpio 4g, Carapax et Plastrum Testudinis 30g, Radix Notoginseng 9g, Radix Saposhnikoviae 14g, Rhizoma Corydalis 8g, Radix Angelicae Sinensis 13g, Radix Curcumae 10g, Rhizoma Cibotii 12g, Radix Glycyrrhizae 12g.

Embodiment 2:

A kind of Chinese medicine composition treating rheumatoid arthritis, it is characterised in that each component of described Chinese medicine composition and Mass parts ratio is as follows:

Herba Ephedrae 11g, Radix Clematidis 14g, Os pardi 26g, Radix Achyranthis Bidentatae 13g, Radix Angelicae Pubescentis 13g, Cortex Eucommiae 14g, Rhizoma Gastrodiae 11g, Fructus Corni (enucleation) 11g, bar halberd 16g, Radix Gentianae Macrophyllae 9g, Stigma Croci 4.2g, Fructus Alpiniae Oxyphyllae 11g, Rhizoma Chuanxiong 11g, Scorpio 34.5g, Carapax et Plastrum Testudinis 35g, Radix Notoginseng 10g, anti- Wind 16g, Rhizoma Corydalis 9g, Radix Angelicae Sinensis 14g, Radix Curcumae 11g, Rhizoma Cibotii 13g, Radix Glycyrrhizae 13g.

Embodiment 3:

A kind of Chinese medicine composition treating rheumatoid arthritis, it is characterised in that each component of described Chinese medicine composition and Mass parts ratio is as follows:

Herba Ephedrae 12g, Radix Clematidis 16g, Os pardi 30g, Radix Achyranthis Bidentatae 15g, Radix Angelicae Pubescentis 15g, Cortex Eucommiae 16g, Rhizoma Gastrodiae 12g, Fructus Corni (enucleation) 12g, bar halberd 18g, Radix Gentianae Macrophyllae 10g, Stigma Croci 4.5g, Fructus Alpiniae Oxyphyllae 12g, Rhizoma Chuanxiong 12g, Scorpio 5g, Carapax et Plastrum Testudinis 40g, Radix Notoginseng 11g, Radix Saposhnikoviae 18g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 16g, Radix Curcumae 12g, Rhizoma Cibotii 15g, Radix Glycyrrhizae 15g.

Model case:

Through clinical conditions patient with rheumatoid arthritis totally 130 example, the age is 99 examples of more than 52 years old, and only 31 examples are 52 Below Sui.98 examples of recovery from illness in 130 example patients, 32 effective examples, total effective rate reaches 100%.After treatment, symptom substantially alleviates Or recovery from illness.

Claims (3)

1. the Chinese medicine composition treating rheumatoid arthritis, it is characterised in that each component of described Chinese medicine composition And mass parts ratio is as follows:

Herba Ephedrae 1.5～12g, Radix Clematidis 10～16g, Os pardi 15～30g, Radix Achyranthis Bidentatae 5～15g, Radix Angelicae Pubescentis 3～15g, the Cortex Eucommiae 6～ 16g, Rhizoma Gastrodiae 3～12g, Fructus Corni (enucleation) 6～12g, bar halberd 6～18g, Radix Gentianae Macrophyllae 3～10g, Stigma Croci 1.5～4.5g, Fructus Alpiniae Oxyphyllae Core 3～12g, Rhizoma Chuanxiong 3～12g, Scorpio 3～5g, Carapax et Plastrum Testudinis 15～40g, Radix Notoginseng 3～11g, Radix Saposhnikoviae 8～18g, Rhizoma Corydalis 3～10g, when Return 8～16g, Radix Curcumae 3～12g, Rhizoma Cibotii 3～15g, Radix Glycyrrhizae 2.5～15g.

The Chinese medicine composition for the treatment of rheumatoid arthritis the most according to claim 1, it is characterised in that described Chinese drug-treated group Each component of compound and mass parts ratio thereof are as follows:

Herba Ephedrae 8～11g, Radix Clematidis 11～14g, Os pardi 20～26g, Radix Achyranthis Bidentatae 8～13g, Radix Angelicae Pubescentis 8～13g, the Cortex Eucommiae 8～14g, Rhizoma Gastrodiae 6～11g, Fructus Corni (enucleation) 8～11g, bar halberd 10～16g, Radix Gentianae Macrophyllae 6～9g, Stigma Croci 2～4.2g, Fructus Alpiniae Oxyphyllae 6～ 11g, Rhizoma Chuanxiong 6～11g, Scorpio 3.5～4.5g, Carapax et Plastrum Testudinis 20～35g, Radix Notoginseng 6～10g, Radix Saposhnikoviae 10～16g, Rhizoma Corydalis 6～9g, when Return 10～14g, Radix Curcumae 6～11g, Rhizoma Cibotii 8～13g, Radix Glycyrrhizae 6～13g.

3. according to the Chinese medicine composition of the treatment rheumatoid arthritis described in claim 1 to 2, it is characterised in that in described Each component of drug composition and mass parts ratio thereof are as follows:

Herba Ephedrae 10g, Radix Clematidis 13g, Os pardi 23g, Radix Achyranthis Bidentatae 12g, Radix Angelicae Pubescentis 12g, Cortex Eucommiae 13g, Rhizoma Gastrodiae 10g, Fructus Corni (enucleation) 10g, bar halberd 14g, Radix Gentianae Macrophyllae 8g, Stigma Croci 4g, Fructus Alpiniae Oxyphyllae 10g, Rhizoma Chuanxiong 10g, Scorpio 4g, Carapax et Plastrum Testudinis 30g, Radix Notoginseng 9g, Radix Saposhnikoviae 14g, Rhizoma Corydalis 8g, Radix Angelicae Sinensis 13g, Radix Curcumae 10g, Rhizoma Cibotii 12g, Radix Glycyrrhizae 12g.