CN106266965A - 一种治疗儿童疳积的中药组合物 - Google Patents

一种治疗儿童疳积的中药组合物 Download PDF

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CN106266965A
CN106266965A CN201610793833.7A CN201610793833A CN106266965A CN 106266965 A CN106266965 A CN 106266965A CN 201610793833 A CN201610793833 A CN 201610793833A CN 106266965 A CN106266965 A CN 106266965A
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马英杰
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Abstract

本发明涉及一种治疗儿童疳积的中药组合物，它包含下列重量份的物质：白术30‑50份、苍术30‑50份、黄芩20‑40份、三棱10‑20份、莪术15‑20份、陈皮30‑50份、炒莱菔子30‑50份、阿魏10‑20份、银柴胡10‑30份、地骨皮10‑30份、使君子5‑10份、焦山楂30‑60份、焦麦芽30‑60份、焦神曲30‑60份、焦槟榔10‑30份、青皮10‑30份、枳实10‑30份、元胡10‑30份、鸡屎藤10‑30份、云苓30‑50份、川厚朴10‑30份、炒鸡内金20‑50份、甘草10‑30份、砂仁15‑40份、草果10‑30份、知母10‑30份、百合30‑50份、薏米30‑50份、扁豆15‑30份、胡黄连6‑15份、芦荟3‑10份和枳壳40‑100份。

Description

一种治疗儿童疳积的中药组合物
技术领域
本发明涉及医药领域，具体来说涉及一种治疗儿童疳积的中药组合物。
背景技术
疳积是一种儿童常见多发病，历来为儿科四大症(痘、麻、惊、疳)之一，属于消化、吸收、营养不良综合症。钱乙在《小儿药证直诀》中指出：“疳皆脾胃病，亡津液之所作也”。王肯堂《证治准绳》论述：“大抵疳之为病，皆过餐饮食，于家一脏有积不治，传之余脏，而成五疳之疾。若脾家病去，则余脏皆安；苟失其治，日久必有传变”。现代研究表明，疳积由致病菌引起。
发明内容
本发明的目的是提供一种治疗儿童疳积的中药组合物。
为了实现本发明的目的，本发明提供一种治疗儿童疳积的中药组合物，它包含下列重量份的物质：白术30-50份、苍术30-50份、黄芩20-40份、三棱10-20份、莪术15-20份、陈皮30-50份、炒莱菔子30-50份、阿魏10-20份、银柴胡10-30份、地骨皮10-30份、使君子5-10份、焦山楂30-60份、焦麦芽30-60份、焦神曲30-60份、焦槟榔10-30份、青皮10-30份、枳实10-30份、元胡10-30份、鸡屎藤10-30份、云苓30-50份、川厚朴10-30份、炒鸡内金20-50份、甘草10-30份、砂仁15-40份、草果10-30份、知母10-30份、百合30-50份、薏米30-50份、扁豆15-30份、胡黄连6-15份、芦荟3-10份和枳壳40-100份。
优选地，本发明所述的治疗儿童疳积的中药组合物包含下列重量份的物质：白术40份、苍术40份、黄芩30份、三棱15份、莪术18份、陈皮40份、炒莱菔子40份、阿魏15份、银柴胡20份、地骨皮20份、使君子8份、焦山楂45份、焦麦芽45份、焦神曲45份、焦槟榔20份、青皮20份、枳实20份、元胡20份、鸡屎藤20份、云苓40份、川厚朴20份、炒鸡内金30份、甘草20份、砂仁25份、草果20份、知母20份、百合40份、薏米40份、扁豆25份、胡黄连10份、芦荟6份和枳壳60份。
更优选地，本发明所述的治疗儿童疳积的中药组合物还包含下列重量份的物质：1.5份的具有下列结构式的物质：
本发明还提供具有下列结构式的物质在制备治疗儿童疳积的药物中的用途：
优选地，所述药物制成膏剂。
本发明所述的药物，具有重要意义和较高的实用价值。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例1
称取白术40克、苍术40克、黄芩30克、三棱15克、莪术18克、陈皮40克、炒莱菔子40克、阿魏15克、银柴胡20克、地骨皮20克、使君子8克、焦山楂45克、焦麦芽45克、焦神曲45克、焦槟榔20克、青皮20克、枳实20克、元胡20克、鸡屎藤20克、云苓40克、川厚朴20克、炒鸡内金30克、甘草20克、砂仁25克、草果20克、知母20克、百合40克、薏米40克、扁豆25克、胡黄连10克、芦荟6克和枳壳60克，加入150000毫升水，在回流的条件下加热5小时，过滤，使滤液冷却至室温，然后经0.22μm的微孔滤膜过滤，得到溶液1。
实施例2
称取0.2克的下列化合物，加入60000毫升无菌水，超声30分钟，然后0.22μm的微孔滤膜过滤，得到溶液2：
体外抑制嗜热链球菌ATCC 14485的试验
采用本领域中经典的滤纸片法来进行抑菌试验。
供试菌种嗜热链球菌ATCC 14485购自上海坤肯生物化工有限公司。
培养液
营养琼脂和营养肉汤，购自北京中科晨宇实验设备有限公司。
试验方法
将嗜热链球菌ATCC 14485接种于琼脂平板营养液平面上，接种时均匀密布。
镊取无菌圆形滤纸片，分别喷洒5ml的实施例1中的溶液、5ml的实施例2中的溶液、2.5ml的实施例1中的溶液+2.5ml的实施例2中的溶液，至完全润湿，贴在已接种细菌的琼脂平板营养液平面上。将琼脂平板置于37℃的培养箱内，温育8小时。测量抑菌环的直径。测定3次取平均值。
1.4结果
实施例1中的溶液的嗜热链球菌ATCC 14485的抑菌环的平均直径为12.36mm，实施例2中的溶液的嗜热链球菌ATCC 14485的抑菌环的平均直径为14.13mm，实施例1中的溶液+实施例2中的溶液的嗜热链球菌ATCC 14485的抑菌环的平均直径为13.55mm。

Claims (5)

1.一种治疗儿童疳积的中药组合物，其特征在于，它包含下列重量份的物质：白术30-50份、苍术30-50份、黄芩20-40份、三棱10-20份、莪术15-20份、陈皮30-50份、炒莱菔子30-50份、阿魏10-20份、银柴胡10-30份、地骨皮10-30份、使君子5-10份、焦山楂30-60份、焦麦芽30-60份、焦神曲30-60份、焦槟榔10-30份、青皮10-30份、枳实10-30份、元胡10-30份、鸡屎藤10-30份、云苓30-50份、川厚朴10-30份、炒鸡内金20-50份、甘草10-30份、砂仁15-40份、草果10-30份、知母10-30份、百合30-50份、薏米30-50份、扁豆15-30份、胡黄连6-15份、芦荟3-10份和枳壳40-100份。
2.根据权利要求1所述的治疗儿童疳积的中药组合物，其特征在于，它包含下列重量份的物质：白术40份、苍术40份、黄芩30份、三棱15份、莪术18份、陈皮40份、炒莱菔子40份、阿魏15份、银柴胡20份、地骨皮20份、使君子8份、焦山楂45份、焦麦芽45份、焦神曲45份、焦槟榔20份、青皮20份、枳实20份、元胡20份、鸡屎藤20份、云苓40份、川厚朴20份、炒鸡内金30份、甘草20份、砂仁25份、草果20份、知母20份、百合40份、薏米40份、扁豆25份、胡黄连10份、芦荟6份和枳壳60份。
3.根据权利要求1所述的治疗儿童疳积的中药组合物，其特征在于，它还包含下列重量份的物质：1.5份的具有下列结构式的物质：
4.具有下列结构式的物质在制备治疗儿童疳积的药物中的用途：
5.根据权利要求4所述的用途，其特征在于，所述药物制成膏剂。
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