CN106266918A - A kind of Chinese medicine composition treating cancer pain and preparation method thereof - Google Patents

Abstract

The present invention relates to technical field of Chinese medicine, it is specifically related to a kind of Chinese medicine composition treating cancer pain and preparation method thereof, it is to be prepared from by the raw material of following parts by weight: the Radix Angelicae Dahuricae 30 to 60 parts, Ganoderma 40 to 80 parts, Herba Chelidonii 40 to 80 parts, Radix Salviae Miltiorrhizae 30 to 90 parts, Fructus Amomi 30 to 90 parts, Flos Caryophylli 40 to 90 parts, Olibanum 30 to 90 parts, Rhizoma Corydalis 60 to 90 parts, Semen Strychni 80 to 120 parts, Semen Sinapis Albae 80 to 120 parts, Radix Aconiti 80 to 120 parts, preparation technology of the present invention is simple, pure Chinese medicine formula, there is blood circulation promoting and blood stasis dispelling, pain relieving is eased pain, effect of dissipating blood stasis for subsidence of swelling, treatment cancer pain has significant effect, without any side effects, and it is cheap.

Description

A kind of Chinese medicine composition treating cancer pain and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition treating cancer pain and preparation side thereof Method.

Background technology

Cancer pain is one of the most frightened symptom of tumor patient, often more fearful than the death that cancer causes.Cancer pain is not only Make patient agonize, but also a series of serious impact can be brought, the development of tumor can be accelerated；Nausea and vomiting, appetite subtract Move back, anxiety, fear, depression, be reluctant and people contacts；Various body functions go down, and mobility declines；Life and treatment are lost Confidence etc..The huge infringement that health, physiology and psychological aspects are caused by pain, not only significantly affects the quality of life of patient, But also influence whether enforcement and the effect of disease treatment.Some patients is lost patience because pain does not obtains Satisfactory Control, very To abandoning effecting a radical cure the chance of cancer.

To carry out, affect the key factor of life quality the most in widespread attention as affecting effective antitumor plan for cancer pain.For Alleviate and control patient's misery, strengthen cancer patient's autoimmunity, improve quality of life and the quality of life of cancer patient, mesh The method of front conventional pain relieving is injecting anesthetic medicine, though these medicines energy reduction of patient pain, patient's life-time service is easily generated Dependency, and patient is the most addicted, along with the progress of the state of an illness also needs escalated dose and shortens administration time, therefore side effect is big.

Summary of the invention

For the deficiencies in the prior art, the present invention provides a kind of Chinese medicine composition treating cancer pain and preparation method thereof, tool Blood circulation promoting and blood stasis dispelling, pain relieving analgesia, effect of dissipating blood stasis for subsidence of swelling, treatment cancer pain is had to have significant effect.

The technical scheme is that and be achieved in that: a kind of Chinese medicine composition treating cancer pain, it is by following weight The raw material of number is prepared from: the Radix Angelicae Dahuricae 30 to 60 parts, Ganoderma 40 to 80 parts, Herba Chelidonii 40 to 80 parts, Radix Salviae Miltiorrhizae 30 to 90 parts, sand Core 30 to 90 parts, Flos Caryophylli 40 to 90 parts, Olibanum 30 to 90 parts, Rhizoma Corydalis 60 to 90 parts, Semen Strychni 80 to 120 parts, Semen Sinapis Albae 80 To 120 parts, Radix Aconiti 80 to 120 parts.

It is to be prepared from by the raw material of following parts by weight: the Radix Angelicae Dahuricae 40 to 55 parts, Ganoderma 50 to 70 parts, Herba Chelidonii 50 To 70 parts, Radix Salviae Miltiorrhizae 40 to 80 parts, Fructus Amomi 40 to 80 parts, Flos Caryophylli 50 to 85 parts, Olibanum 40 to 80 parts, Rhizoma Corydalis 70 to 85 parts, horse Semen Strychni 90 to 110 parts, Semen Sinapis Albae 90 to 110 parts, Radix Aconiti 90 to 110 parts.

It is to be prepared from by the raw material of following parts by weight: the Radix Angelicae Dahuricae 50 parts, Ganoderma 65 parts, Herba Chelidonii 60 parts, Radix Salviae Miltiorrhizae 75 parts, Fructus Amomi 70 parts, Flos Caryophylli 70 parts, Olibanum 75 parts, Rhizoma Corydalis 80 parts, Semen Strychni 100 parts, Semen Sinapis Albae 100 parts, Radix Aconiti 100 parts.

Its preparation method is as follows:

1) choose above-mentioned raw materials, by raw material pulverizing to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain mixing Material；

2) reflux, extract, that added water by compound 3 to 4 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, every time Extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, by normal for gained filtrate room temperature Pressure sterilization treatment, obtains medicinal liquid；

3) by step 2) in the medicinal liquid that obtains carry out bottling by 20 milliliters every bottle and seal standby.

The present invention has no side effect, and prescription drug pharmacology is:

The Radix Angelicae Dahuricae: pungent, temperature.Return stomach, large intestine, lung meridian.Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, declare clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.

Ganoderma: sweet, flat.GUIXIN, lung, liver, kidney channel.Invigorating QI and tranquilization, relieving cough and asthma.For malaise, cardiopalmus of having a sleepless night, lung Empty cough with asthma, asthenia loses heart, anorexia.

Herba Chelidonii: bitter is cool；Poisonous.Attach to the lung and stomach meridians.Relieving spasm to stop pain, relieving cough and asthma.For gastral cavilty spasm and pain, cough and asthma, Pertussis.

Radix Salviae Miltiorrhizae: bitter, is slightly cold.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For the thoracic obstruction heart Bitterly, gastral cavity abdomen hypochondriac pain, abdominal mass accumulation, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache.

Fructus Amomi: pungent, temperature.Return spleen, stomach, kidney channel.Removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass The most hungry, Deficiency and coldness of spleen and stomach, vomiting has loose bowels, pregnancy reactions, frequent fetal movement.

Flos Caryophylli: pungent, temperature.Return spleen, stomach, lung, kidney channel.Warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, singultus is vomitted, food Few vomiting and diarrhoea, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.

Olibanum: pungent, bitter, temperature.GUIXIN, liver, spleen channel.Invigorate blood circulation analgesic therapy, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, bitterly Through amenorrhea, postpartum stagnation, abdominal mass stomachache, rheumatic arthralgia, muscle arteries and veins contracture, traumatic injury, carbuncle skin infection.

Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.For breast the side of body, epigastric pain, obstruction of qi in the chest and cardialgia, Amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.

Semen Strychni: bitter, temperature；Very toxic.Return liver, spleen channel.Removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For traumatic injury, fracture is swollen Bitterly, rheumatoid arthritis stubborn, paralysis and numbness, skin sore, laryngopharynx swelling and pain.

Semen Sinapis Albae: pungent, temperature.Return lung meridian.Warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.Cough for cold-phlegm, distending pain in the chest and hypochondrium, The stagnant meridians of expectorant, joint numbness, pain, phlegm-damp oozing in the body, carbuncle of yin nature toxic swelling.

Radix Aconiti: pungent, bitter, heat；Very toxic.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, Arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain and narcotic analgesic.

Usage of the present invention and consumption be: the method for being prepared as described above prepares clinical sample, and specification is 20 milliliters every bottle, within five days, is One course for the treatment of, one day three bottles, take point early, middle and late three half an hour ante cibum.Take medicine period avoid eating anything raw or cold, pungent, stimulate and rot Thing.

The present invention has a following beneficial effect: preparation technology of the present invention is simple, pure Chinese medicine formula, have blood circulation promoting and blood stasis dispelling, Pain relieving analgesia, effect of dissipating blood stasis for subsidence of swelling, treatment cancer pain has significant effect, without any side effects and cheap.

Concrete case citing:

Zhang, man, 50 years old, people from Nanyang.With chest pain, cough, expectorant blood is chief complaint January, and in February, 2013, pulmonary wears Thorn pathological diagnosis is: inferior lobe of right lung Small Cell Lung Cancer With Selective finds that again the right hip big lesser tubercle of subcutaneous about 2 × 3cm2 wears long simultaneously Thorn case turns out to be lung carcinoma subcutaneous transfer.Use chemotherapy immediately.Just when chemotherapy second time, left scapular region pain, active receiving occur Limit, finds osteolytic bone destruction after i.e. clapping CR, it is considered to bone metastases of lung cancer.Here, oral one, two step analgesia Western medicine are difficult to Alleviating pain, narcotic analgesic medicine probably addiction family members are reluctant to accept, and in examining at the beginning of 2014 7 months, through taking this medicinal liquid 20 My god, pain subtracts greatly, and spirit is hearty, and the quality of life such as appetite, sleep and people's contacts significantly improves, and existing still adheres to taking every day, hip Portion's subcutaneous nodule is obviously reduced more than 2/3, can do work in power.

Poplar, female, 40 years old, find breast carcinoma 3 years, period constantly seeks medical advice and medicine, and tried various Therapeutic Method, and all paid no attention to Thinking, after using 4 liang of courses for the treatment of of this formula later, pain has alleviated, and adheres to afterwards taking, can orthobiosis.

Wang, man, 52 years old, find hepatocarcinoma 4 years, tried Western medicine chemotherapeutics, effect is undesirable, uses this to join later After square 6 courses for the treatment of, pain has alleviated, and adheres to afterwards taking, can orthobiosis.

Detailed description of the invention

A kind of Chinese medicine composition treating cancer pain, it is to be prepared from by the raw material of following parts by weight: the Radix Angelicae Dahuricae 30 to 60 parts, Ganoderma 40 to 80 parts, Herba Chelidonii 40 to 80 parts, Radix Salviae Miltiorrhizae 30 to 90 parts, Fructus Amomi 30 to 90 parts, Flos Caryophylli 40 to 90 parts, Olibanum 30 to 90 parts, Rhizoma Pinelliae 20 to 50 parts, Rhizoma Corydalis 60 to 90 parts, Semen Strychni 80 to 120 parts, Semen Sinapis Albae 80 to 120 parts, Radix Aconiti 80 To 120 parts.It is to be prepared from by the raw material of following parts by weight: the Radix Angelicae Dahuricae 40 to 55 parts, Ganoderma 50 to 70 parts, Herba Chelidonii 50 To 70 parts, Radix Salviae Miltiorrhizae 40 to 80 parts, Fructus Amomi 40 to 80 parts, Flos Caryophylli 50 to 85 parts, Olibanum 40 to 80 parts, Rhizoma Pinelliae 30 to 45 parts, prolongs Rhizoma Corydalis 70 to 85 parts, Semen Strychni 90 to 110 parts, Semen Sinapis Albae 90 to 110 parts, Radix Aconiti 90 to 110 parts.It is by following parts by weight Raw material be prepared from: the Radix Angelicae Dahuricae 50 parts, Ganoderma 65 parts, Herba Chelidonii 60 parts, Radix Salviae Miltiorrhizae 75 parts, Fructus Amomi 70 parts, Flos Caryophylli 70 parts, Olibanum 75 parts, Rhizoma Pinelliae 40 parts, Rhizoma Corydalis 80 parts, Semen Strychni 100 parts, Semen Sinapis Albae 100 parts, Radix Aconiti 100 parts.Its preparation method is as follows: 1) choose above-mentioned raw materials, by raw material pulverizing to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；2) The reflux, extract, that added water by compound 3 to 4 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, when extracting every time Between be 1 to 3 hour, merge the extracting solution of each gained, by extracting solution filter, obtain filtrate, will go out under gained filtrate normal temperature and pressure Bacterium processes, and obtains medicinal liquid；3) by step 2) in the medicinal liquid that obtains carry out bottling by 20 milliliters every bottle and seal standby.

Embodiment 1: take the Radix Angelicae Dahuricae 30 parts, Ganoderma 40 parts, Herba Chelidonii 40 parts, Radix Salviae Miltiorrhizae 30 parts, Fructus Amomi 30 parts, Flos Caryophylli 40 parts, breast Fragrant 30 parts, Rhizoma Pinelliae 20 parts, Rhizoma Corydalis 60 parts, Semen Strychni 80 parts, Semen Sinapis Albae 80 parts, Radix Aconiti 80 parts, they are crushed to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；The reflux, extract, that added water by compound 3 to 4 times, adds water every time Amount is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges the extracting solution of each gained, will Extracting solution filters, and obtains filtrate, by sterilization treatment under gained filtrate normal temperature and pressure, obtains medicinal liquid；By the medicinal liquid that obtains by every bottle 20 milli Liter carries out bottling and seals standby.

Embodiment 2: take the Radix Angelicae Dahuricae 60 parts, Ganoderma 80 parts, Herba Chelidonii 80 parts, Radix Salviae Miltiorrhizae 90 parts, Fructus Amomi 90 parts, Flos Caryophylli 90 parts, breast Fragrant 90 parts, Rhizoma Pinelliae 50 parts, Rhizoma Corydalis 90 parts, Semen Strychni 120 parts, Semen Sinapis Albae 120 parts, Radix Aconiti 120 parts, they are crushed to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；Reflux, extract, that compound is added water 3 to 4 times, often Secondary amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges carrying of each gained Take liquid, extracting solution is filtered, obtains filtrate, by sterilization treatment under gained filtrate normal temperature and pressure, obtain medicinal liquid；By the medicinal liquid that obtains by often 20 milliliters of bottle carries out bottling and seals standby.

Embodiment 3: take the Radix Angelicae Dahuricae 40 parts, Ganoderma 50 parts, Herba Chelidonii 50 parts, Radix Salviae Miltiorrhizae 40 parts, Fructus Amomi 40 parts, Flos Caryophylli 50 parts, breast Fragrant 40 parts, Rhizoma Pinelliae 30 parts, Rhizoma Corydalis 70 parts, Semen Strychni 90 parts, Semen Sinapis Albae 90 parts, Radix Aconiti 90 parts, they are crushed to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；The reflux, extract, that added water by compound 3 to 4 times, adds water every time Amount is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges the extracting solution of each gained, will Extracting solution filters, and obtains filtrate, by sterilization treatment under gained filtrate normal temperature and pressure, obtains medicinal liquid；By the medicinal liquid that obtains by every bottle 20 milli Liter carries out bottling and seals standby.

Embodiment 4: take the Radix Angelicae Dahuricae 55 parts, Ganoderma 70 parts, Herba Chelidonii 70 parts, Radix Salviae Miltiorrhizae 80 parts, Fructus Amomi 80 parts, Flos Caryophylli 85 parts, breast Fragrant 80 parts, Rhizoma Pinelliae 45 parts, Rhizoma Corydalis 85 parts, Semen Strychni 110 parts, Semen Sinapis Albae 110 parts, Radix Aconiti 110 parts, they are crushed to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；Reflux, extract, that compound is added water 3 to 4 times, often Secondary amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges carrying of each gained Take liquid, extracting solution is filtered, obtains filtrate, by sterilization treatment under gained filtrate normal temperature and pressure, obtain medicinal liquid；By the medicinal liquid that obtains by often 20 milliliters of bottle carries out bottling and seals standby.

Embodiment 5: take the Radix Angelicae Dahuricae 50 parts, Ganoderma 65 parts, Herba Chelidonii 60 parts, Radix Salviae Miltiorrhizae 75 parts, Fructus Amomi 70 parts, Flos Caryophylli 70 parts, breast Fragrant 75 parts, Rhizoma Pinelliae 40 parts, Rhizoma Corydalis 80 parts, Semen Strychni 100 parts, Semen Sinapis Albae 100 parts, Radix Aconiti 100 parts, they are crushed to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain compound；Reflux, extract, that compound is added water 3 to 4 times, often Secondary amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, and each extraction time is 1 to 3 hour, merges carrying of each gained Take liquid, extracting solution is filtered, obtains filtrate, by sterilization treatment under gained filtrate normal temperature and pressure, obtain medicinal liquid；By the medicinal liquid that obtains by often 20 milliliters of bottle carries out bottling and seals standby.

Claims (4)

1. the Chinese medicine composition treating cancer pain, it is characterised in that it is to be prepared from by the raw material of following parts by weight: The Radix Angelicae Dahuricae 30 to 60 parts, Ganoderma 40 to 80 parts, Herba Chelidonii 40 to 80 parts, Radix Salviae Miltiorrhizae 30 to 90 parts, Fructus Amomi 30 to 90 parts, Flos Caryophylli 40 to 90 Part, Olibanum 30 to 90 parts, Rhizoma Pinelliae 20 to 50 parts, Rhizoma Corydalis 60 to 90 parts, Semen Strychni 80 to 120 parts, Semen Sinapis Albae 80 to 120 Part, Radix Aconiti 80 to 120 parts.

The Chinese medicine composition for the treatment of cancer pain the most according to claim 1, it is characterised in that it is by following parts by weight Raw material is prepared from: the Radix Angelicae Dahuricae 40 to 55 parts, Ganoderma 50 to 70 parts, Herba Chelidonii 50 to 70 parts, Radix Salviae Miltiorrhizae 40 to 80 parts, Fructus Amomi 40 to 80 parts, Flos Caryophylli 50 to 85 parts, Olibanum 40 to 80 parts, Rhizoma Pinelliae 30 to 45 parts, Rhizoma Corydalis 70 to 85 parts, Semen Strychni 90 to 110 parts, Semen Sinapis Albae 90 to 110 parts, Radix Aconiti 90 to 110 parts.

The Chinese medicine composition for the treatment of cancer pain the most according to claim 1, it is characterised in that it is by following parts by weight Raw material is prepared from: the Radix Angelicae Dahuricae 50 parts, Ganoderma 65 parts, Herba Chelidonii 60 parts, Radix Salviae Miltiorrhizae 75 parts, Fructus Amomi 70 parts, Flos Caryophylli 70 parts, Olibanum 75 Part, Rhizoma Pinelliae 40 parts, Rhizoma Corydalis 80 parts, Semen Strychni 100 parts, Semen Sinapis Albae 100 parts, Radix Aconiti 100 parts.

4. the preparation method of the Chinese medicine composition of a treatment cancer pain as claimed in claim 1, it is characterised in that its preparation side Method is as follows:

1) choose above-mentioned raw materials, by raw material pulverizing to 150 to 200 mesh, the raw material mix homogeneously after then pulverizing, obtain mixing Material；

2) reflux, extract, that added water by compound 3 to 4 times, each amount of water is equivalent to 6 to 8 times of above-mentioned raw materials gross weight, every time Extraction time is 1 to 3 hour, merges the extracting solution of each gained, is filtered by extracting solution, obtains filtrate, by normal for gained filtrate room temperature Pressure sterilization treatment, obtains medicinal liquid；

3) by step 2) in the medicinal liquid that obtains carry out bottling by 20 milliliters every bottle and seal standby.