CN106265343A - A kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof - Google Patents
A kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof Download PDFInfo
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- CN106265343A CN106265343A CN201610833052.6A CN201610833052A CN106265343A CN 106265343 A CN106265343 A CN 106265343A CN 201610833052 A CN201610833052 A CN 201610833052A CN 106265343 A CN106265343 A CN 106265343A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof, be made up of following raw material: vitamin C injection 50 70 parts, 37 parts of Flos Rosae Rugosae pistil, Flos Chrysanthemi 37 parts, Fructus Cucumidis sativi 6 10 parts, Radix Rauvolfiae 59 parts, Fructus Lycopersici esculenti 48 parts, Fructus Fragariae Ananssae 7 11 parts.Other raw materials after clean process are put in container by preparation method: poured into by vitamin C injection in container, soak 10 15 hours under room temperature, filter, bottle.The fruit and vegerable VC nutrition skin lotion of the present invention has antipruritic skin moistening, whitening skin and preserving moisture, promotion skin metabolism effect, have light speckle anti-acne concurrently, strengthen the multi-efficiency such as skin elasticity, discharge skin toxin, Cucumber Extract, during use, can skin permeation rapidly, human body skin is not had toxic and side effects and zest, safe and reliable.
Description
Technical field
The present invention relates to technical field of skin care, particularly relate to a kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof.
Background technology
Along with development and the raising of living standard of society, people increasingly pay attention to the beauty of appearance outward appearance.Can be by
In the impact of all factors, cause some people seeking beauty, it is difficult to have pale skin, an appearance that water is tender, cause this dimness
The reason of unglazed dry hydropenia skin quality has a lot, such as geneogenous inherited genetic factors, subhealth state factor posteriority, disease factor,
Dietary factor, environmental factors etc..
At present, moisturising product of improving looks in market is numerous, but various businessman is in order to make product have effect for the moment, often to
Wherein add various industrial chemicals, such as contain the heavy metal component such as lead, hydrargyrum.Although adding the skin care item tool for the moment of industrial chemicals
Having beauty treatment skin moistening effect, but be difficult to by percutaneous absorption and have certain zest, skin can be caused damage by life-time service, right
Health causes a series of harm.Along with beauty treatment, the needs of skin protection are gradually stepped up by people, people more favor in natural next
Source fruit and vegerable are the skin care item of raw material.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of fruit and vegerable VC nutrition skin lotion and preparation side thereof
Method, is made by vitamin C immersion bubble fruit and vegerable, has antipruritic skin moistening, whitening skin and preserving moisture, promotion skin metabolism effect, have concurrently
The multi-efficiency such as desalination wrinkle of skin, light speckle anti-acne, the skin elasticity that strengthens, discharge skin toxin, Cucumber Extract, appearance luster is pleased
Mesh, uniformity, have natural flavor, during use, it is possible to skin permeation rapidly, does not has toxic and side effects and stimulation to human body skin
Property, safe and reliable, being suitable for the crowd at each age of men and women, old and young uses, and preparation method is simple.
To achieve these goals, the present invention adopts the following technical scheme that
A kind of fruit and vegerable VC nutrition skin lotion, is made up of the raw material of following weight portion: vitamin C injection 50-70 part, Flos Rosae Rugosae
Pistil 3-7 part, Flos Chrysanthemi 3-7 part, Fructus Cucumidis sativi 6-10 part, Radix Rauvolfiae 5-9 part, Fructus Lycopersici esculenti 4-8 part, Fructus Fragariae Ananssae 7-11 part.
Preferably, described fruit and vegerable VC nutrition skin lotion, it is made up of the raw material of following weight portion: vitamin C injection 58-
62 parts, Flos Rosae Rugosae pistil 4-6 part, Flos Chrysanthemi 4-6 part, Fructus Cucumidis sativi 7-9 part, Radix Rauvolfiae 6-8 part, Fructus Lycopersici esculenti 5-7 part, Fructus Fragariae Ananssae 8-10 part.
Described vitamin C injection is commercially available vitamin C injection.
Preferably, described vitamin C injection includes vitamin C, sodium diethyldithiocarbamate, ethylenediamine tetraacetic
Acetic acid disodium, sodium pyrosulfite, Cys, sodium bicarbonate and water for injection, described ascorbic concentration is 15-20g/
L, the concentration of sodium diethyldithiocarbamate is 0.5-0.8g/L, and the concentration of disodiumedetate is 0.3-0.5g/
L, the concentration of sodium pyrosulfite is 1-2g/L, and the concentration of Cys is 8-10g/L, and the concentration of sodium bicarbonate is for making vitamin
The pH value of C injection is 6.0-6.5.Preparation method is: be first sequentially added into second two in the water for injection saturated by carbon dioxide
Amine tetraacethyl disodium, sodium pyrosulfite and Cys, add vitamin C after being completely dissolved, stirring makes vitamin C the most molten
Solve, be subsequently adding sodium bicarbonate, add sodium diethyldithiocarbamate, be eventually adding water for injection constant volume, mixed
Close solution；Then adding needle-use activated carbon in mixed solution, filter decarburization after stirring 10-20min, the filtrate after filtering is used
Aperture is the ultrafilter membrane fine straining of 0.22nm；Then the filtrate after fine straining is continually fed into carbon dioxide, at aeration condition
Sterilizing after lower embedding, obtains vitamin C injection.This vitamin C injection is by adding stabilizer diethyl-dithio amino
Sodium formate, coordinates sodium pyrosulfite, Cys, vitamin C can be protected not oxidized in storing process, table in appearance
Now for turning to be yellow, significantly extending the effect duration of vitamin C injection, the stability making vitamin C injection is big greatly
By force.
The preparation method of described fruit and vegerable VC nutrition skin lotion, comprises the following steps:
(1) pretreatment of raw material: pluck new fresh-rose stamen and Flos Chrysanthemi, cleans；By fresh Fructus Cucumidis sativi, Radix Rauvolfiae, western red
Fructus Kaki and Fructus Fragariae Ananssae are cleaned respectively, remove seed, are then cut into sheet；
(2) vitamin C injection is poured in container, by pretreated Flos Rosae Rugosae pistil, Flos Chrysanthemi and tableted Huang
Melon, Radix Rauvolfiae, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae are put in container, soak 10-15 hour at normal temperatures；
(3) filter, filtrate is bottled.
Using method: the skin lotion of the present invention uses once for 5-7 days.
Each raw material explanation in the present invention:
Vitamin C injection, containing vitamin C, plays regulatory role the metabolism of human body, can promote ossein
Biosynthesis, the beneficially faster healing of tissue injury mouth, promote TYR and the metabolism of tryptophan in aminoacid, extend human body
In the life-span, strengthen anti-stress ability and the immunity of human body environment to external world, can be with Whitening, spot, antioxidation, and promote other
The absorption of composition.
Flos Rosae Rugosae, maintaining beauty and keeping young is notable, promoting blood circulation to remove blood stasis, the withered skin of improvement, blood circulation promoting and metabolism,
There is the effect of delay skin aging, moisturizing, smoothing wrinkle.
Flos Chrysanthemi, has wind-dispelling heat-dissipating, heat-clearing and toxic substances removing, suppression pathogenic bacteria and antibacterial effect, cures mainly rheumatism, integumentary musculature bad
Wait indefinitely.
Fructus Cucumidis sativi, containing abundant vitamin E, plays and extends human body life-span, the effect of defying age, the cucumber chitinase in Fructus Cucumidis sativi,
There is the strongest biological activity, the metabolism of body can be effectively facilitated, have skin moistening, unfold effect of wrinkle.
Radix Rauvolfiae, effective ingredient capsaicin is a kind of antioxidant, can stop the metabolism about cell, thus whole
The only Carcinogenesis of cell tissue, reduces the incidence rate of cancer cell, and capsaicin can alleviate skin pain, have sterilization,
Effect of antipruritic pain relieving.
Fructus Lycopersici esculenti, has effect of radioprotective, moisturizing, anti-inflammation, anti-acne, whitening and speckle dispelling, can promote collagen protein
Synthesis, strengthen skin elasticity, prevent scaly dry skin aging.Containing abundant lycopene in Fructus Lycopersici esculenti, lycopene has
Unique oxidation resistance, can remove free radical, and repair cell damages, the Oxidation of suppression DNA, and slow down aging promotes thin
Born of the same parents regenerate；Containing protein, cellulose, saccharide, it is possible to remove black eye, whitening and moistening skin, promotion immune function of human body；Fructus Lycopersici esculenti
In containing alkali, it is possible to suppress the fungus harmful for human body, antiphlogistic antibacterial.
Fructus Fragariae Ananssae, belongs to berry, and sugar content is up to 6%-10%, and containing multiple fruit acid, vitamin and mineral etc., can strengthen skin
Skin is elastic, has brightening and moistens effect of moisturizing；And have deoil, the effect of clean skin, it is to avoid pigmentation.
Compared with the prior art, beneficial effects of the present invention is as follows:
The fruit and vegerable VC nutrition skin lotion of the present invention, with vitamin C injection as primary raw material, by add Flos Rosae Rugosae pistil,
The fruit and vegerable such as Flos Chrysanthemi and Fructus Cucumidis sativi, Radix Rauvolfiae, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae compound, equilibrium collocation, and Synergistic has antipruritic profit
Skin, whitening skin and preserving moisture, promotion skin metabolism effect, have desalination wrinkle of skin, light speckle anti-acne concurrently, strengthen skin elasticity, discharge
The multi-efficiencies such as skin toxin, Cucumber Extract, life-time service, can improve the metabolic function in the nutrition of skin and cortex, increase
Add skin cytoactive, suppress melanic generation, make whitening skin, smooth tender, flexible；The skin lotion outward appearance of the present invention
Color and luster is pleasing, uniformity, has natural flavor, during use, it is possible to skin permeation rapidly, and human body skin is not had toxic and side effects
And zest, safe and reliable, it is suitable for the crowd at each age of men and women, old and young and uses.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, but the present invention is not limited only to these embodiments, not
On the premise of departing from present inventive concept, within any improvement made all falls within protection scope of the present invention.
Embodiment 1:
A kind of fruit and vegerable VC nutrition skin lotion, is made up of the raw material of following weight portion: vitamin C injection 55 parts, Flos Rosae Rugosae
Stamen 3 parts, Flos Chrysanthemi 6 parts, Fructus Cucumidis sativi 6 parts, Radix Rauvolfiae 8 parts, Fructus Lycopersici esculenti 4 parts, Fructus Fragariae Ananssae 11 parts.
Described vitamin C injection is commercially available vitamin C injection.
The preparation method of described fruit and vegerable VC nutrition skin lotion, comprises the following steps:
(1) pretreatment of raw material: pluck new fresh-rose stamen and Flos Chrysanthemi, cleans；By fresh Fructus Cucumidis sativi, Radix Rauvolfiae, western red
Fructus Kaki and Fructus Fragariae Ananssae are cleaned respectively, remove seed, are then cut into sheet；
(2) vitamin C injection is poured in container, by pretreated Flos Rosae Rugosae pistil, Flos Chrysanthemi and tableted Huang
Melon, Radix Rauvolfiae, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae are put in container, soak 10 hours at normal temperatures；
(3) filter, filtrate is bottled.
Embodiment 2:
A kind of fruit and vegerable VC nutrition skin lotion, is made up of the raw material of following weight portion: vitamin C injection 60 parts, Flos Rosae Rugosae
Stamen 5 parts, Flos Chrysanthemi 5 parts, Fructus Cucumidis sativi 8 parts, Radix Rauvolfiae 7 parts, Fructus Lycopersici esculenti 6 parts, Fructus Fragariae Ananssae 9 parts.
Described vitamin C injection includes vitamin C, sodium diethyldithiocarbamate, ethylenediaminetetraacetic acid two
Sodium, sodium pyrosulfite, Cys, sodium bicarbonate and water for injection, described ascorbic concentration is 15-20g/L, diethyl
The concentration of base nabam is 0.5-0.8g/L, and the concentration of disodiumedetate is 0.3-0.5g/L, Jiao Ya
The concentration of sodium sulfate is 1-2g/L, and the concentration of Cys is 8-10g/L, and the concentration of sodium bicarbonate is injected for making vitamin C
The pH value of liquid is 6.0-6.5.Preparation method is: be first sequentially added into ethylenediamine tetrem in the water for injection saturated by carbon dioxide
Acid disodium, sodium pyrosulfite and Cys, add vitamin C after being completely dissolved, stirring makes vitamin C be completely dissolved, so
Rear addition sodium bicarbonate, adds sodium diethyldithiocarbamate, is eventually adding water for injection constant volume, obtains mixing molten
Liquid；Then in mixed solution, add needle-use activated carbon, after stirring 10-20min, filter decarburization, the filtrate aperture after filtering
Ultrafilter membrane fine straining for 0.22nm；Then the filtrate after fine straining is continually fed into carbon dioxide, fills under aeration condition
It is honored as a queen sterilizing, obtains vitamin C injection.
The preparation method of described fruit and vegerable VC nutrition skin lotion, comprises the following steps:
(1) pretreatment of raw material: pluck new fresh-rose stamen and Flos Chrysanthemi, cleans；By fresh Fructus Cucumidis sativi, Radix Rauvolfiae, western red
Fructus Kaki and Fructus Fragariae Ananssae are cleaned respectively, remove seed, are then cut into sheet；
(2) vitamin C injection is poured in container, by pretreated Flos Rosae Rugosae pistil, Flos Chrysanthemi and tableted Huang
Melon, Radix Rauvolfiae, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae are put in container, soak 12 hours at normal temperatures；
(3) filter, filtrate is bottled.
Embodiment 3:
A kind of fruit and vegerable VC nutrition skin lotion, is made up of the raw material of following weight portion: vitamin C injection 70 parts, Flos Rosae Rugosae
Stamen 7 parts, Flos Chrysanthemi 3 parts, Fructus Cucumidis sativi 7 parts, Radix Rauvolfiae 9 parts, Fructus Lycopersici esculenti 5 parts, Fructus Fragariae Ananssae 8 parts.
Described vitamin C injection is commercially available vitamin C injection.
The preparation method of described fruit and vegerable VC nutrition skin lotion, comprises the following steps:
(1) pretreatment of raw material: pluck new fresh-rose stamen and Flos Chrysanthemi, cleans；By fresh Fructus Cucumidis sativi, Radix Rauvolfiae, western red
Fructus Kaki and Fructus Fragariae Ananssae are cleaned respectively, remove seed, are then cut into sheet；
(2) vitamin C injection is poured in container, by pretreated Flos Rosae Rugosae pistil, Flos Chrysanthemi and tableted Huang
Melon, Radix Rauvolfiae, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae are put in container, soak 15 hours at normal temperatures；
(3) filter, filtrate is bottled.
Effect test example:
(1) B16 cell test in suppression mouse melanin cell
By B16 mouse melanin tumor cell with 1 × 105The density of individual/ml is connected to the culture dish of a diameter of 9cm, at 37 DEG C
5%CO2Under conditions of cultivate 2 days, abandon supernatant, add the sample solution 18-22ml after filtration sterilization, be then incubated for 3 days, abandon
Supernatant, PBS washs, and every hole adds the trypsin solution peptic cell 3min of 0.5ml mass percent 0.2%, and every ware adds 2ml dimension
Hold liquid and terminate digestion. after piping and druming mixing, every kind of concentration is taken out 0.5ml and is made cell counting. remaining cell suspension with 2500r/min from
Heart 5min, abandons supernatant, adds NaoH solution in precipitation, and heating makes melanin dissolve, and selects the enzyme linked immunological of 490nm wavelength
Absorbance is surveyed on detector.
B16 cell suppression ratio=(1-(medicine hole absorbance+medicine porocyte density)+(control wells absorbance+right
According to porocyte density)) × 100%.
B16 cell test in suppression mouse melanin cell, result is as shown in table 1:
Table 1
| Suppression ratio (%) | |
| Embodiment 1 | 63.5 |
| Embodiment 2 | 68.7 |
| Embodiment 3 | 65.6 |
Above-mentioned result of the test shows, the skin lotion of the present invention can effectively suppress melanin to generate, and the skin lotion of embodiment 2
Most pronounced effects.
(2) skin moisturizing test
Subjects: the tester 60 in age 18-60 year, wherein women 40, male 20.Test position is left
Cheek, comparison position is right cheek.
Test method: the skin lotion that tester uses embodiment 2 in every 5 days smears skin once, and the time is 15 days；Use
Skin elasticity tester MPA580 Detection results.In result of the test, skin elasticity strengthen degree more than 15% for skin moisturizing
Effect is preferable.Result of the test such as table 2 below.
Result of the test:
Table 2
| Within 15 days, skin elasticity strengthens degree | Women (people) | Male (people) |
| 5-10% | 2 | 3 |
| 16-40% | 8 | 9 |
| More than 40% | 30 | 8 |
Above-mentioned result of the test shows, after 30 days, it is preferable that women group has the tester of 95% to show as skin moisturizing effect,
It is preferable that male's group has the tester of 85% to show as skin moisturizing effect, thus, human body skin is had by the skin lotion of the present invention
Preferably moisten effect.
(3) practical example:
1, application form tried out by nutrition skin lotion of the present invention
Remarks: 1: after use, effect is fine；2: after use, effect is preferable；3: after use, effect is general；4: to no effect.
2, Classical examples
Lee, female, Anqing, 20 years old, once itching endlessly to skin in autumn is dry, wipe a lot of skin care item and all loseed onset.
After using the skin lotion of the embodiment of the present invention 2, within 5 days, using once, after two weeks, the dry phenomenon of itching of skin greatly takes a turn for the better, skin light
Sliding tender, flexible.
Permitted certain, female, Lu'an City, 30 years old, owing to making the skin allergy redness caused that applies some make up, pruritus, goose pimples occurs,
After skin lotion by the embodiment of the present invention 2, within 7 days, use once, used began to no longer pruritus the same day, after the week, skin
Skin slowly starts to recover, and after adhering to using 28 days, skin becomes pale, smooth, tender, flexible.
Wang, female, Hefei City, 45 years old, xerosis cutis was turned to be yellow, and face has wrinkle, used the skin moistening of the embodiment of the present invention 2
Liquid, uses once for 5 days, and after 20 days, skin starts smooth tender, and wrinkle significantly reduces, it appears that young more many than original.
Zhang, man, Hefei City, 21 years old, start long pox pachylosis the most on the face from ten dark and gloomy, can send out during dry weather
Itch, used a large amount of skin care item, all loseed obvious curative effects, used the skin lotion of the embodiment of the present invention 1, within 5 days, used once, 10 days
After, skin is obvious smooth to be much continuing with, and comedo and pox print disappear the most simultaneously, and skin quality thoroughly changes.
Claims (4)
1. a fruit and vegerable VC nutrition skin lotion, it is characterised in that: it is made up of the raw material of following weight portion: vitamin C injection 50-
70 parts, Flos Rosae Rugosae pistil 3-7 part, Flos Chrysanthemi 3-7 part, Fructus Cucumidis sativi 6-10 part, Radix Rauvolfiae 5-9 part, Fructus Lycopersici esculenti 4-8 part, Fructus Fragariae Ananssae 7-11 part.
Fruit and vegerable VC nutrition skin lotion the most according to claim 1, it is characterised in that: it is made up of the raw material of following weight portion:
Vitamin C injection 58-62 part, Flos Rosae Rugosae pistil 4-6 part, Flos Chrysanthemi 4-6 part, Fructus Cucumidis sativi 7-9 part, Radix Rauvolfiae 6-8 part, Fructus Lycopersici esculenti 5-
7 parts, Fructus Fragariae Ananssae 8-10 part.
Fruit and vegerable VC nutrition skin lotion the most according to claim 1 and 2, it is characterised in that: described vitamin C injection bag
Include vitamin C, sodium diethyldithiocarbamate, disodiumedetate, sodium pyrosulfite, Cys, carbonic acid
Hydrogen sodium and water for injection, described ascorbic concentration is 15-20g/L, and the concentration of sodium diethyldithiocarbamate is 0.5-
0.8g/L, the concentration of disodiumedetate is 0.3-0.5g/L, and the concentration of sodium pyrosulfite is 1-2g/L, Cys
Concentration be 8-10g/L, the concentration of sodium bicarbonate is that to make the pH value of vitamin C injection be 6.0-6.5.
The preparation method of fruit and vegerable VC nutrition skin lotion the most according to claim 1, it is characterised in that: comprise the following steps:
(1) pretreatment of raw material: pluck new fresh-rose stamen and Flos Chrysanthemi, cleans；By fresh Fructus Cucumidis sativi, Radix Rauvolfiae, Fructus Lycopersici esculenti and
Fructus Fragariae Ananssae is cleaned respectively, removes seed, is then cut into sheet；
(2) vitamin C injection is poured in container, by pretreated Flos Rosae Rugosae pistil, Flos Chrysanthemi and tableted Fructus Cucumidis sativi, green grass or young crops
Fructus Capsici, Fructus Lycopersici esculenti, Fructus Fragariae Ananssae are put in container, soak 10-15 hour at normal temperatures；
(3) filter, filtrate is bottled.
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| CN201610833052.6A CN106265343A (en) | 2016-09-20 | 2016-09-20 | A kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof |
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| CN201610833052.6A CN106265343A (en) | 2016-09-20 | 2016-09-20 | A kind of fruit and vegerable VC nutrition skin lotion and preparation method thereof |
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Application publication date: 20170104 |
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