CN106264781A - The manufacture method of overlay film frame, system - Google Patents
The manufacture method of overlay film frame, system Download PDFInfo
- Publication number
- CN106264781A CN106264781A CN201510358283.1A CN201510358283A CN106264781A CN 106264781 A CN106264781 A CN 106264781A CN 201510358283 A CN201510358283 A CN 201510358283A CN 106264781 A CN106264781 A CN 106264781A
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- China
- Prior art keywords
- overlay film
- core
- film frame
- support
- manufacture method
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
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- Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses the manufacture method of a kind of overlay film frame, system, this manufacture method includes: first step, according to the blood vessel structure Design and Machining core of support to be implanted；Second step, processes described overlay film frame on described core；And third step, described core is separated with described overlay film frame.Therefore, first core can be processed according to the human vas structure of support to be implanted, and after the skeleton of support and overlay film have combined according to the structure of this core, core is separated with overlay film frame, thus it is manufactured that the overlay film frame that the blood vessel with different structure matches dexterously, it is achieved the customization of overlay film frame.And step is simply easily achieved, practical.
Description
Technical field
The present invention relates to the manufacture manufacture field of overlay film frame in intravascular stent, in particular it relates to one is covered
The manufacture method of membrane support.
Background technology
Along with the arriving of aging society, for radially supporting the application of the intravascular stent that blood vessel blockage occurs
More and more.Wherein, with implantation position and treatment disease plant difference, the kind of intravascular stent, structure and
Implantation is the most different.At present, widely used support includes bare bracket, coating bracket and overlay film
Support, the expansion mode of support can be divided into ball to expand mode and from swollen mode.Wherein overlay film frame is mainly used in
The big blood vessel such as aorta.It includes passive support skeleton, and is attached on this support skeleton
Overlay film.Wherein, in prior art, the manufacture of overlay film frame manufactures support overlay film and support bone the most respectively
Frame, and support overlay film is seamed on support skeleton by silk thread.And overlay film frame of the prior art
Although plurality of specifications can be fabricated to adapt to different blood vessel as far as possible.But, various due to human vas
Property, disease locus is the most various.Thus cause this mode cannot realize the knot of the blood vessel to Different Individual
The adaptation of structure.Thus form internal hemorrhage due to trauma or thrombosis owing to can not fit with blood vessel after causing Vascular implantation, make
The effect becoming intravascular stent is poor, and the state of an illness is easily multiple, the problem that complication is many.
Therefore it provides a kind of intravascular stent manufacturing technology that can customize according to specific human vas has
Positive effect.
Summary of the invention
It is an object of the present invention to provide the manufacture method of a kind of overlay film frame, this manufacture method is ingenious easily
OK, it is possible to according to the overlay film frame that the customization of feature human vas is different.
It is a further object of the present invention to provide the manufacture system of a kind of overlay film frame, this manufacture system can be real
The manufacture method that the existing present invention provides.
To achieve these goals, according to an aspect of the present invention, it is provided that the manufacture of a kind of overlay film frame
Method, this manufacture method includes: first step, according to the blood vessel structure Design and Machining type of support to be implanted
Core；Second step, processes described overlay film frame on described core；And third step, by described type
Core separates with described overlay film frame.
Preferably, in described first step, process described core by 3D printing technique.
Preferably, soluble material is used to process described core.
Preferably, glucide is used to process described core.
Preferably, in described third step, by described core dissolution, so that described core is with described
Overlay film frame separates.
Preferably, in described second step, including suit step and integrating step, in described suit step
In Zhou, the support skeleton of described overlay film frame is sleeved on described core, in described integrating step,
The covering material of described overlay film frame is attached on described support skeleton.
Preferably, described suit step occurs in described integrating step, in described integrating step, first
On described core, first process ground floor support overlay film, then perform described suit step, finally described
Process second layer support overlay film on support skeleton, and this second layer support overlay film is propped up with described ground floor
Frame overlay film combines, to realize described covering material and the combination of described support skeleton.
Preferably, in described integrating step, by thermal spraying, Electrospun or controllable deposition technology in institute
State and on core, process described covering material.
According to a further aspect in the invention, it is provided that the manufacture system of a kind of overlay film frame, including: core adds
Construction equipment, processes core for the blood vessel structure according to support to be implanted；Suit equipment, for described
The support skeleton of described overlay film frame it is set with on core；Bonding apparatus, for covering described overlay film frame
Membrane material is attached on described support skeleton form the support overlay film of described overlay film frame；And separation sets
It is standby, for described core is separated with described overlay film frame.
Preferably, described core process equipment is 3D printer.
Preferably, described bonding apparatus is hot spray apparatus, electric spinning device or controllable deposition device.
Preferably, described separation equipment is for dissolving utensil.
By technique scheme, first the present invention ties according to the human vas of support to be implanted
Structure processes core, and after the skeleton of support and overlay film have combined according to the structure of this core, this type
Core can separate with overlay film frame, thus is manufactured that what the blood vessel with different structure matched covers dexterously
Membrane support, and step is simply easily achieved, practical.
Other features and advantages of the present invention will be described in detail in detailed description of the invention part subsequently.
Accompanying drawing explanation
Accompanying drawing is used to provide a further understanding of the present invention, and constitutes the part of description, with
Detailed description below is used for explaining the present invention together, but is not intended that limitation of the present invention.?
In accompanying drawing:
Fig. 1 is the structured flowchart of the manufacture system that the present invention provides.
Description of reference numerals
1 core process equipment 2 braiding apparatus
3 bonding apparatus 4 separation equipments
Detailed description of the invention
Below in conjunction with accompanying drawing, the detailed description of the invention of the present invention is described in detail.It should be appreciated that
Detailed description of the invention described herein is merely to illustrate and explains the present invention, is not limited to this
Bright.
As it is shown in figure 1, the present invention provides the manufacture method of a kind of overlay film frame and realizes this manufacture method
Manufacture system.The overlay film frame that wherein present invention is to be manufactured includes support skeleton and is combined in this support skeleton
On support overlay film.Wherein, support skeleton can be by for metal material, such as metal tantalum, medical not
The rust metal such as steel and Nitinol is made, and support overlay film can be by PTFE (politef) etc.
The membrane structure that macromolecular material is formed.
In order to realize the purpose of the present invention, i.e. realize the customization to overlay film frame, the manufacture that the present invention provides
Method includes: first step, according to the blood vessel structure Design and Machining core of support to be implanted；Second step,
Core is processed overlay film frame；And third step, core is separated with overlay film frame.In other words,
The feature of the manufacture method that the present invention provides is first to set according to the human vas structure of support to be implanted
Meter processes core, i.e. can imitate out the structure of particular blood vessel with this core, then add on this core
Work overlay film frame, finally separates this core with overlay film frame, such that it is able to be manufactured that dexterously
The overlay film frame matched with the blood vessel of different structure, and step is simply easily achieved, practical.
In order to realize this manufacture method, the present invention also provides for the manufacture system of a kind of overlay film frame.Below in conjunction with
The optimal way of this manufacture method introduces the manufacture system that the present invention provides.
It should be noted that the embodiment being capable of foregoing invention design has multiple, such as core
Separate mode of processing method, core and overlay film frame etc., for convenience of explanation present invention, at this
Introducing preferred implementation therein, this preferred implementation is served only for the present invention is described, and need not
In limiting the present invention.
In a preferred embodiment of the invention, in order to accurately, conveniently obtain the type suited with blood vessel structure
Core, it is preferable that in the first step, processes core by 3D printing technique.That is, the present invention provides
Manufacture system in, perform first step core process equipment 1 be 3D printer.Specifically, setting
During meter core, band can be obtained by medical means such as radiographies and implant the blood vessel structure of holder part, such as
CT radiography, then builds and this blood vessel in a computer according to the blood vessel structure of this support portions to be implanted
The threedimensional model that structure suits, then completes the processing and manufacturing of core by 3D printer.Wherein need
It is noted that the intravascular stent owing to finally giving needs to adapt with blood vessel, therefore should in guarantee
While the outer surface structure of core and the interior wall construction of blood vessel adapt, the dimensions of core can root
Designing according to the error precision needed for doctor, the processing method for different error precisions all should fall at this
In bright protection domain.That is, it is to manufacture on the basis of the outer surface of core due to overlay film frame, covers
Membrane support needs to be implanted on the inwall of blood vessel, the most also need to need according to doctor's when processing core
Requirement, design makes core exterior surface dimension be less than the size of blood vessel with required error, so that
Whole overlay film frame adapts to blood vessel.Wherein, core its can be that hollow-core construction can also be for solid knot
Structure, does not limits this present invention.Wherein in view of convenient processing, core is preferably solid construction body.
Wherein for the ease of the processing of core, soluble material can be used to process core, such as, adopt
Core is processed with water-soluble material.More specifically, it is possible to use glucide processing core, the most permissible
Readily obtain the core of solid-state.The most importantly, using liquid soluble materials processing core is in order to more preferably
Realize core and manufacture complete overlay film frame be separated from each other.The most preferably, in order to complete efficiently
Above-mentioned third step, can be by core dissolution, so that core separates with overlay film frame.That is, the present invention
For performing the separation equipment 4 of third step for dissolving utensil, this dissolving utensil in the manufacture system provided
The dissolving of core can be completed by applying the lysate for core material.In such manner, it is possible in side
Just, while processing and manufacturing core, the separation of core and overlay film frame is the most conveniently completed.Thus
Obtain support to be implanted.In other embodiments, core can also use fusible material to make,
As long as when separating core, use firing equipment to be melted by core, this kind of mode of texturing also should
Fall in protection scope of the present invention.
Above describe the processing with core and separate relevant first step and third step, below to
Two steps are introduced.In the second step, in order to complete the processing of overlay film frame, need on core
Support skeleton and support overlay film are be combined with each other.Wherein support skeleton can be the ring of individual pen, according to type
The specification of core selects the support ring of different size in case installing to combine with overlay film after on core with at set.Separately
Outward, support skeleton can also be whole piece silk thread, and set installs to the appearance of core in the way of by voluble wrapping
On face, thus obtain suitable support skeleton.Should fall equally at the protection model of the present invention for this mode
In enclosing.That is, in the second step that the present invention provides, including suit step and integrating step, at suit
In step, the support skeleton of overlay film frame is sleeved on core, in integrating step, by overlay film frame
Covering material be attached on support skeleton.Specifically, in the manufacture system that the present invention provides, including
Perform the suit equipment of suit step and perform the bonding apparatus of integrating step.
For the ease of the two being combined, in the second step, design suit step occurs in integrating step
In, specifically, in integrating step, on core, first process ground floor support overlay film, then perform
Suit step, finally continues executing with integrating step, i.e. processes second layer support overlay film on support skeleton,
And this second layer support overlay film is combined with described ground floor support overlay film, to realize described covering material
Combination with described support skeleton.That is, among support skeleton being firmly clipped in by two-layer overlay film front and back,
With the combination that both realizations are stable.
Support skeleton and the combination of support overlay film the most for convenience, is different from stitching skill of the prior art
Art, the present invention utilizes the feature of support covering material dexterously, can directly be attached to support overlay film prop up
On frame skeleton and form stable overall structure.In order to realize this mode, it is preferable that in the present invention,
The technology such as thermal spraying, Electrospun or controllable deposition can be passed through and will process covering material.That is, combination is performed
The bonding apparatus 3 of step is hot spray apparatus, electric spinning device or controllable deposition equipment.This, permissible
Covering material feature is utilized, it is achieved support overlay film and the stable bond of support skeleton by ingenious.Wherein heat
The technology that spraying, Electrospinning and controllable deposition technology are known in the art, does not do at this and too much repeats.
To sum up, the manufacture method of the overlay film frame that the present invention provides is ingenious easy, it is possible to realize for difference
The customization of the overlay film frame of blood vessel structure, has higher practicality and promotional value.
The preferred embodiment of the present invention is described in detail above in association with accompanying drawing, but, the present invention does not limit
Detail in above-mentioned embodiment, in the technology concept of the present invention, can be to the present invention
Technical scheme carry out multiple simple variant, these simple variant belong to protection scope of the present invention.
It is further to note that each the concrete technology described in above-mentioned detailed description of the invention is special
Levy, in the case of reconcilable, can be combined by any suitable means, in order to avoid need not
The repetition wanted, various possible compound modes are illustrated by the present invention the most separately.
Additionally, combination in any can also be carried out between the various different embodiment of the present invention, as long as its
Without prejudice to the thought of the present invention, it should be considered as content disclosed in this invention equally.
Claims (12)
1. the manufacture method of an overlay film frame, it is characterised in that this manufacture method includes:
First step, according to the blood vessel structure Design and Machining core of support to be implanted；
Second step, processes described overlay film frame on described core；And
Third step, separates described core with described overlay film frame.
Manufacture method the most according to claim 1, it is characterised in that in described first step,
Described core is processed by 3D printing technique.
Manufacture method the most according to claim 2, it is characterised in that use soluble material to add
Core described in work.
Manufacture method the most according to claim 3, it is characterised in that use glucide processing
Described core.
Manufacture method the most according to claim 1, it is characterised in that in described third step,
By described core dissolution, so that described core separates with described overlay film frame.
Manufacture method the most according to claim 1, it is characterised in that in described second step,
Including suit step and integrating step, in described suit step, by the support skeleton of described overlay film frame
It is sleeved on described core, in described integrating step, the covering material of described overlay film frame is attached to
On described support skeleton.
Manufacture method the most according to claim 6, it is characterised in that described suit step occurs
In described integrating step, in described integrating step, on described core, first process ground floor support
Overlay film, then performs described suit step, finally processes second layer support overlay film on described support skeleton,
And this second layer support overlay film is combined with described ground floor support overlay film, to realize described covering material
Combination with described support skeleton.
8. according to the manufacture method described in claim 6 or 7, it is characterised in that walk in described combination
In Zhou, on described core, process described covering material by thermal spraying, Electrospun or controllable deposition technology.
9. a manufacture system for overlay film frame, including:
Core process equipment (1), processes core for the blood vessel structure according to support to be implanted；
Suit equipment (2), for being set with the support skeleton of described overlay film frame on described core；
Bonding apparatus (3), for being attached to described support skeleton by the covering material of described overlay film frame
To form the support overlay film of described overlay film frame；And
Separation equipment (4), for separating described core with described overlay film frame.
Manufacture system the most according to claim 9, it is characterised in that described core process equipment
(1) it is 3D printer.
11. manufacture systems according to claim 9, it is characterised in that described bonding apparatus (3)
For hot spray apparatus, electric spinning device or controllable deposition device.
12. manufacture systems according to claim 9, it is characterised in that described separation equipment (4)
For dissolving utensil.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510358283.1A CN106264781A (en) | 2015-06-25 | 2015-06-25 | The manufacture method of overlay film frame, system |
| PCT/CN2016/085969 WO2016206561A1 (en) | 2015-06-25 | 2016-06-16 | Manufacturing method and system of covered stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510358283.1A CN106264781A (en) | 2015-06-25 | 2015-06-25 | The manufacture method of overlay film frame, system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106264781A true CN106264781A (en) | 2017-01-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510358283.1A Pending CN106264781A (en) | 2015-06-25 | 2015-06-25 | The manufacture method of overlay film frame, system |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN106264781A (en) |
| WO (1) | WO2016206561A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726003B (en) * | 2016-12-30 | 2018-03-13 | 上海长海医院 | Dissection of aorta intravascular stent and its manufacture method |
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| Publication number | Publication date |
|---|---|
| WO2016206561A1 (en) | 2016-12-29 |
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Application publication date: 20170104 |