CN106244356A - A kind of infant detergent - Google Patents
A kind of infant detergent Download PDFInfo
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- CN106244356A CN106244356A CN201610604773.XA CN201610604773A CN106244356A CN 106244356 A CN106244356 A CN 106244356A CN 201610604773 A CN201610604773 A CN 201610604773A CN 106244356 A CN106244356 A CN 106244356A
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- China
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- cylinder
- radix stemonae
- swingle
- extract
- hothouse
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/40—Products in which the composition is not well defined
- C11D7/44—Vegetable products
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/267—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/268—Carbohydrates or derivatives thereof
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Abstract
The present invention is a kind of infant detergent, the extracting method of a kind of Radix Stemonae extract is provided, preparation method is: take the Radix Stemonae, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being concentrated into 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stirring, stand, filter, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, use microwave extracting, obtain Radix Stemonae extract, prepare tuberostemoenone content high, and it is prepared as infant detergent with avicularin and bergenin compatibility.
Description
Technical field
The present invention relates to technical field of extraction of Chinese traditional medicine, the extracting method and the infant that are specifically related to a kind of Radix Stemonae extract are washed
Clothing powder.
Background technology
The extracting method of Radix Stemonae extract in prior art, technique is coarse, backward, and impurity is many, and active constituent content is low, leads
Cause patient's consumption excessive, it has not been convenient to take, had a strong impact on this product and applied clinically.
Summary of the invention
Goal of the invention: in order to solve the problems referred to above, it is an object of the invention to provide the extraction side of a kind of Radix Stemonae extract
Method and infant detergent.
Technical scheme: it is an object of the invention to by following scheme realization:
The extracting method of a kind of Radix Stemonae extract, preparation method is: take the Radix Stemonae, adds the water of 10 times of weight, soaks 0.5h, decocts
Boiling 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, concentrate
Being 1.05 to 60 DEG C of relative densities, add ethanol and make the percent by volume of alcohol content reach 75%, stirring, standing, filtration, filtrate concentrates
It is 1.25 to relative density when 65 DEG C, and reclaims ethanol, obtain concentrated solution, use microwave extracting, concentrate, be dried, obtain the Radix Stemonae and extract
Thing.
Described microwave assisted extraction methods is: is put in microwave extracting apparatus by the concentrated solution after water extract-alcohol precipitation and carries out microwave extraction
Take, extract power 400-600W, extract 2 times, each 4-8 minute, amount is concentrated solution weight the 2 of 70% ethanol of addition every time
Times, obtaining extract, concentrate, optimum condition is: microwave extracting power 500W, every time extraction 6 minutes.
The extracting method of described Radix Stemonae extract, concentrates in said extracted method and uses device, including concentrating cylinder, arranges
At the vaporizer of described concentration cylinder body bottom, it is provided with venthole at the top of described concentration cylinder and condenses panel, described solidifying
It is provided with cooling liquid storage chamber in junction plate, is provided with at the top of described concentration cylinder and entering that described cooling liquid storage chamber is connected
Liquid pipe and discharge pipe, it is characterised in that: the roof in described concentration cylinder is provided with the swingle downwardly extended, described swingle
Being provided with scraper dish, the web of described scraper dish contacts, at the roof of described concentration cylinder with the inwall concentrating cylinder
Being provided with lift cylinder, the top of described swingle is connected through roof and the top of described concentration cylinder with described lift cylinder
Connecing, be provided with electric rotating machine in described swingle, the main shaft of described electric rotating machine is connected with the center of described scraper dish,
The top of described concentration cylinder is additionally provided with the elevating lever through roof, is provided with horn-like suction in the bottom of described elevating lever and steeps mouth,
It is provided with in described elevating lever and steeps, with described horn-like suction, the suction bubble passage that mouth is connected, be provided with suction at the top of described elevating lever
The attached pump housing, is provided with regulation cylinder between the roof and described elevating lever of described concentration cylinder, and described elevating lever is in described regulation
In described concentration cylinder, lifting moving is done under the effect of cylinder.
The extracting method of described Radix Stemonae extract, concentrates described in enrichment facility in said extracted method and sets on the sidewall of cylinder
Having observation window, be provided with seal glass in described observation window, described scraper dish is circular, the external diameter of described scraper dish with
Identical and scraper dish the inner ring surface of internal diameter concentrating cylinder is connected with the main shaft of electric rotating machine by dowel bar, described steaming
It is columnar structured for sending out device, and described vaporizer is connected to concentrate the diapire of cylinder by adpting flange, sets in described vaporizer
There is evaporation tube, the sidewall of described vaporizer is provided with the steam inlet being connected with described evaporation tube and steam (vapor) outlet.
The extracting method of described Radix Stemonae extract, is dried in said extracted method and uses device, including hothouse with described
The air quantity conditioning chamber that hothouse is connected, is provided with charging aperture on the roof of described hothouse, sets in the bottom of described hothouse
Having discharging opening, be provided with air intake passage, be provided with air exhaust passage on described hothouse on described air quantity conditioning chamber, its feature exists
In: between described air quantity conditioning chamber and described hothouse, be provided with dividing plate, described dividing plate be uniformly provided with pore, described every
Being additionally provided with the cavity of lateral opening on plate, described cavity is arranged on the side by hothouse, is provided with electric rotating in described cavity
Machine, is additionally provided with the swingle being connected with described electric rotating machine main shaft, is provided with upset paddle, institute on the surface of described swingle
State swingle and stretch in described hothouse, be provided with air guide channel at the center of described swingle, on described upset paddle all
The even hot gas injection jets being connected with described air guide channel that is provided with, when described wind is stretched in the end of described swingle in conditioning chamber,
It is provided with heat conduction blower fan in described air guide channel, is provided with movable plate when described wind in conditioning chamber, set in the side of described movable plate
Have and the air quantity adjusting plug that described pore matches and the air holes that is arranged between adjacent air quantity adjusting plug, described movable plate with
Mobile regulation cylinder it is provided with between the sidewall of described air quantity conditioning chamber.
The extracting method of described Radix Stemonae extract, is dried in said extracted method and uses described air quantity conditioning chamber described in device
Roof be provided with chute, the diapire at described air quantity conditioning chamber is provided with shifting chute, and described shifting chute moves towards one with described chute
Causing, the top of described movable plate is movably arranged in described chute by scroll wheel, and movable block is passed through in the bottom of described movable plate
Being movably arranged in described shifting chute, described mobile regulation cylinder is arranged between described movable block and the end wall of shifting chute.
The extracting method of described Radix Stemonae extract, is dried in said extracted method and uses the main shaft of electric rotating machine described in device
It is provided with driving fluted disc, described swingle is provided with the teeth groove mutually ratcheting with described driving fluted disc, the opening part of described cavity
Being provided with protection network, described swingle is arranged through described protection network.
Infant detergent, said method the Radix Stemonae extract prepared, avicularin, bergenin form.
Described infant detergent, Radix Stemonae extract, avicularin, the weight ratio of bergenin are 8-12:4-6:5-7.
Described infant detergent, Radix Stemonae extract, avicularin, the weight ratio of bergenin are 10:5:6.
In prior art, the original extracting method of the Radix Stemonae, technique is coarse, backward, and impurity is many, causes patient's consumption excessive, no
Conveniently taking, tuberostemoenone content prepared by the present invention increases, and content is high.Concentrator simple in construction in the present invention,
Simple operation, it not only can start scraper dish as required and do lift adjustment as required such that it is able to realize concentration
The inwall of cylinder carries out scraping dirt process, and the descending operation that simultaneously can also regulate elevating lever as required makes horn-like suction at bubble mouth
Being absorbed by the foam on surface by the absorption pump housing just above in medication level, is solved in conventional art medicine enrichment facility and manages
Wall medicine dirt removes the technical deficiency of difficulty, and stability in use is good and the suitability is strong.This drying equipment structure is simple, simple operation,
It is provided with upset paddle and is provided with, in upset paddle, the hot gas injection jets being connected with air quantity conditioning chamber, making at stirring medical material
Medical material is dried simultaneously, adds the speed contacted with medical material, can effectively improve medicinal material drying efficiency, and use steady
Qualitative good, solve the technical deficiency that conventional art pharmaceutical drying device drying efficiency is low, the suitability is strong and practicality good.
Accompanying drawing explanation
In order to make present disclosure be more likely to be clearly understood, below according to specific embodiment and combine accompanying drawing, right
The present invention is described in further detail, wherein:
Fig. 1 is the structural representation of enrichment facility of the present invention.
Fig. 2 is the structural representation of drying device of the present invention.
Detailed description of the invention
Form by the following examples, is described in further detail the foregoing of the present invention again, but should be by this
Being interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to Examples below, all technology realized based on foregoing of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1
Taking Radix Stemonae 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8 times
The water of weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes
The percent by volume of alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims
Ethanol, obtains concentrated solution, uses microwave extracting, concentrates, and is dried, obtains Radix Stemonae extract.
Described microwave assisted extraction methods is: is put in microwave extracting apparatus by the concentrated solution after water extract-alcohol precipitation and carries out microwave extraction
Take, extract power 400W, extract 2 times, each 8 minutes, amount is concentrated solution weight 2 times of 70% ethanol every time added, must
Extract, concentrates.
Seeing Fig. 1: the extracting method of described Radix Stemonae extract, above-mentioned concentration uses device, including concentrating cylinder 1, is arranged on
Vaporizer 2 bottom described concentration cylinder 1, is provided with venthole 3 and condenses panel 4, described at the top of described concentration cylinder 1
It is provided with cooling liquid storage chamber 5 in condensing panel 4, is provided with at the top of described concentration cylinder 1 and is connected with described cooling liquid storage chamber 5
Logical feed tube 6 and discharge pipe 7, be provided with condensation panel, the gas partial coagulation of medicine evaporation at night can be become moisture, be possible to prevent
Drug volatilization is fallen, and the roof in described concentration cylinder 1 is provided with the swingle 8 downwardly extended, and described swingle 8 is provided with scrapes dirt
Cutterhead 9, the web of described scraper dish 9 contacts with the inwall concentrating cylinder 1, is provided with on the roof of described concentration cylinder 1
Lift cylinder 10, the top of described swingle 8 is connected through roof and the top of described concentration cylinder 1 with described lift cylinder 10
Connect, in described swingle 8, be provided with electric rotating machine 11, the center phase of the main shaft of described electric rotating machine 11 and described scraper dish 9
Connect, be additionally provided with the elevating lever 12 through roof at the top of described concentration cylinder 1, be provided with loudspeaker in the bottom of described elevating lever 12
Shape inhales bubble mouth 13, is provided with and steeps the suction bubble passage 14 that mouth 13 is connected, in institute with described horn-like suction in described elevating lever 12
The top stating elevating lever 12 is provided with the absorption pump housing 15, is provided with tune between the roof and described elevating lever 12 of described concentration cylinder 1
Displacements of cylinders 16, described elevating lever does lifting moving under the effect of described regulation cylinder in described concentration cylinder.
The sidewall of described concentration cylinder 1 is provided with observation window 17, in described observation window, is provided with seal glass 18.
Described scraper dish is circular, the external diameter of described scraper dish with concentrate cylinder internal diameter is identical and scraper dish
Inner ring surface be connected with the main shaft of electric rotating machine by dowel bar.It is not to carry out owing to scraping dirt and inhaling bubble simultaneously, so
Both can't cause mutually restriction.
Described vaporizer 2 is columnar structured, and described vaporizer 2 is connected to concentrate the end of cylinder 1 by adpting flange 19
Wall, is provided with evaporation tube 20 in described vaporizer, is provided with and is connected with described evaporation tube 20 on the sidewall of described vaporizer 2
Steam inlet 21 and steam (vapor) outlet 22.
Seeing Fig. 2: the extracting method of described Radix Stemonae extract, above-mentioned dry use device, including including hothouse 1 and institute
State the air quantity conditioning chamber 2 that hothouse 1 is connected, the roof of described hothouse 1 is provided with charging aperture 3, at described hothouse 1
Bottom is provided with discharging opening 4, is provided with air intake passage 5, is provided with air exhaust passage on described hothouse 1 on described air quantity conditioning chamber 2
6, between described air quantity conditioning chamber 2 and described hothouse 1, it is provided with dividing plate 7, described dividing plate 7 is uniformly provided with pore 8, in institute
Stating the cavity 9 being additionally provided with lateral opening on dividing plate 7, described cavity 9 is arranged on the side by hothouse 1, sets in described cavity 9
There is electric rotating machine 10, be additionally provided with the swingle 11 being connected with described electric rotating machine 10 main shaft, on the surface of described swingle 11
Being provided with upset paddle 12, described swingle 11 stretches in described hothouse 1, is provided with inducing QI at the center of described swingle 11 and leads to
Road 13, is uniformly provided with the hot gas injection jets 14 being connected with described air guide channel 13, described rotation on described upset paddle 12
When described wind is stretched in the end of bar 11 in conditioning chamber 2, in described air guide channel 13, it is provided with heat conduction blower fan 15, adjusts when described wind
Joint room 2 in be provided with movable plate 16, be provided with in the side of described movable plate 16 the air quantity adjusting plug 17 matched with described pore 8 and
It is arranged on the air holes 18 between adjacent air quantity adjusting plug, sets between the sidewall of described movable plate 16 and described air quantity conditioning chamber 2
There is mobile regulation cylinder 19.
Roof at described air quantity conditioning chamber 2 is provided with chute 20, and the diapire at described air quantity conditioning chamber 2 is provided with shifting chute
21, described shifting chute 21 is consistent with the trend of described chute 20, and the top of described movable plate 16 is arranged by scroll wheel 22 is movable
In described chute 20, the bottom of described movable plate 16 is movably arranged in described shifting chute 21 by movable block 23, described shifting
Dynamic regulation cylinder 19 is arranged between described movable block 23 and the end wall of shifting chute 21.
The main shaft of described electric rotating machine is provided with driving fluted disc 24, described swingle is provided with and described driving fluted disc
Mutually ratcheting teeth groove 25.
Opening part at described cavity is provided with protection network 26, and described swingle is arranged through described protection network.
Take Radix Stemonae extract prepared by said method, avicularin, the weight ratio of bergenin are 10:5:6, according to a conventional method
It is prepared as infant detergent.
Embodiment 2
Taking Radix Stemonae 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8 times
The water of weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes
The percent by volume of alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims
Ethanol, obtains concentrated solution, uses microwave extracting, concentrates, and is dried, obtains Radix Stemonae extract.
Described microwave assisted extraction methods is: is put in microwave extracting apparatus by the concentrated solution after water extract-alcohol precipitation and carries out microwave extraction
Take, extract power 600W, extract 2 times, each 4 minutes, amount is concentrated solution weight 2 times of 70% ethanol every time added, must
Extract, concentrates.
Concentrate with drying equipment ibid.
Take Radix Stemonae extract prepared by said method, avicularin, the weight ratio of bergenin are 10:4:7, according to a conventional method
It is prepared as infant detergent.
Embodiment 3
Taking Radix Stemonae 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8 times
The water of weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes
The percent by volume of alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims
Ethanol, obtains concentrated solution, uses microwave extracting, concentrates, and is dried, obtains Radix Stemonae extract.
Described microwave assisted extraction methods is: is put in microwave extracting apparatus by the concentrated solution after water extract-alcohol precipitation and carries out microwave extraction
Take, extract power 500W, extract 2 times, each 6 minutes, amount is concentrated solution weight 2 times of 70% ethanol every time added, must
Extract, concentrates.
Concentrate with drying equipment ibid.
Take Radix Stemonae extract prepared by said method, avicularin, the weight ratio of bergenin are 10:6:5, according to a conventional method
It is prepared as infant detergent.
In above-described embodiment, avicularin (30%), bergenin (30%) are purchased from bio tech ltd of AOC, Shaanxi.
Embodiment 4: by method preparation in embodiment 1 without the infant detergent of avicularin.
Embodiment 5: by method preparation in embodiment 1 without the infant detergent of bergenin.
Tuberostemoenone assay experimentation data in the extracting method of embodiment 6 Radix Stemonae extract of the present invention
1.1 Experimental agents: infant detergent of the present invention: prepare by embodiment 1-3 method.According to embodiment in matched group
1 uses common concentration to be prepared as infant detergent with drying means.
1.2 instruments: high performance liquid chromatograph system includes high performance liquid chromatograph (Waters 515)；P200 high-pressure pump；
Waters2487 UV-detector and GJ605 type high pressure six-way injection valve；Data acquisition and process use the work of HS chromatographic data
Stand V4.0+ (Hangzhou English spectrum science and technology).
1.3 condition determinations: measure according to high performance liquid chromatography (general rule 0512).Chromatographic condition and system suitability:
Chromatographic column is SinoChrom ODS (250mm × 4.6mm, 5 μm), flowing mutually for acetonitrile-volume fraction be the phosphoric acid water of 0.5%
Solution, gradient elution, flow velocity: 1.0mL min^-1, detects wavelength: 210nm, column temperature: 30 DEG C.Number of theoretical plate presses radix stemonae tuberosae
Ketenes peak calculates should be not less than 2000.Take tuberostemoenone reference substance appropriate, accurately weighed, add methanol and make every lm l and contain
The solution of 5ug, to obtain final product.The preparation of need testing solution takes this product under content uniformity item, finely ground, takes about 0.5g, accurately weighed, puts
In 25ml measuring bottle, add methanol 20ml, supersound process (power 250W, frequency 40kHz) 30 minutes, let cool, add methanol to scale, shake
Even, filter, take subsequent filtrate, to obtain final product.Precision draws reference substance solution and need testing solution each 20ul injection chromatograph of liquid respectively,
Measure, to obtain final product.
1.4 experimental result
Tuberostemoenone assay result in infant detergent prepared by each embodiment
| Sample source | Tuberostemoenone content (%) |
| Embodiment 1 | 0.48 |
| Embodiment 2 | 0.52 |
| Embodiment 3 | 0.45 |
| Matched group | 0.12 |
According to the result of the test of upper table, radix stemonae tuberosae alkene in infant detergent prepared by embodiment of the present invention 1-3
Ketone content is apparently higher than matched group.
Embodiment 7: the present invention affects result of the test to staphylococcus aureus etc..
Test material: (1) medicine and reagent are by reagent: prepare infant laundry by preparation embodiment 1,4,5 method
Powder；Sodium chloride: the long hundred million chemical reagent company limiteies in Shanghai, lot number: 00090130.Nutrient broth medium: upper marine section insecticide
Biotechnology development corporation, Ltd., lot number: 130616.Nutrient agar: Jiangsu Prov. Disease Preventing and Controlling Center's microorganism
Chemical reagent work, lot number: 130026.Improvement Martin's culture medium: sky, Hangzhou and microorganism reagent company limited, lot number: 130731.Improvement
Martin's culture medium: Beijing three medicine scientific and technological development company, lot number: 131023；Sabouraud's agar: CIQ science is ground
Jiu Yuan Beijing Luqiao Technology Co., Ltd., lot number: 1208156；Calf serum, Hangzhou Ilex purpurea Hassk.[I.chinensis Sims biological engineering material is limited
Company, lot number: 130808；De-fine Sheep Blood, purchased from Jiangning county epidemic prevention station, lot number: 130712 (2) bacterial strain reference cultures: golden yellow
Color staphylococcus (ATCC25923), escherichia coli (441490), beta hemolytic streptococcus (32210), Candida albicans
(98100) provided by Jiangsu Province Disease epizootic prevention center microorganism reagent factory.(3) instrument and equipment electronic balance, Beijing plug is many
Li Si balance company limited produces；Full-automatic high-pressure autoclave, Japan SANYO；Superclean bench, Suzhou Decontamination Equipment Plant；
SHP-80 biochemical cultivation case, Shanghai is gloomy reliable tests Instrument Ltd.
Experimental technique: (1) antibacterial culturing: take reference culture: staphylococcus aureus (ATCC25923), escherichia coli
(441490), beta hemolytic streptococcus (32210) bacterial strain a little, be inoculated in respectively in nutrient broth medium, 37 DEG C of cultivations
18h.(adding 20% calf serum in group B streptococcus broth bouillon) takes each bacterial strain nutrient broth culture that 18h cultivates, and uses
Nutrient broth makees 10-3Dilution is used for testing.Extracting waste candidiasis bacterial strain is a little, is inoculated in improvement Martin's culture medium, 35 DEG C of trainings
Support 24h.Take the Candida albicans culture that 24h cultivates, be used for testing with improvement Martin's culture medium 10-3 dilution.(2) two times dilute
Interpretation of the law (test tube method): take sterilizing test tubes 11, the 1st pipe adds nutrient broth fluid medium 1.6ml, remaining every pipe 1ml, respectively
Taking and added in the first pipe by reagent diluent 0.4ml, take 1ml to the 2nd pipe, dilute successively after mixing, the 10th pipe sucking-off 1ml abandons
Going, the 11st pipe is not added with medicinal liquid as comparison.Often pipe adds dilution bacterium solution 0.1ml, cultivates 24h for 37 DEG C.Take out and observe bacterial growth
Situation.As drug liquid tube is muddy, i.e. represent bacterial growth, for reagent thing without bacteriostasis；Then expression antibacterial as limpid in drug liquid tube is raw
Length is suppressed, the medicinal liquid of the greatest dilution of its energy bacteria growing inhibiting, is the minimal inhibitory concentration (MIC) of this medicine.
By limpid medicinal liquid meat soup each pipe transferred species broth agar plates, cultivating 24h and observe, still the minimum drug level without bacterial growth is
Bacteriocidal concentration for this medicine.
Experimental result: antibacterial activity in vitro of the present invention (n=2), unit is: minimum inhibitory concentration (MIC) (g crude drug/g).
The embodiment of the present invention 1,4,5 anti-inflammation test
| Sample source | Staphylococcus aureus | Escherichia coli | Group B streptococcus | Candida albicans |
| Embodiment 1 | 0.01 | 0.04 | 0.03 | 0.05 |
| Embodiment 4 | 0.8 | 0.9 | 0.5 | 0.7 |
| Embodiment 5 | 0.6 | 0.7 | 0.8 | 0.6 |
Show: 1,4,5 pairs of staphylococcus aureuses (ATCC25923) of embodiment, escherichia coli (441490), beta hemolysis
Property streptococcus (32210), Candida albicans are respectively provided with stronger bacteriostasis；Wherein embodiment 1 is better than embodiment 4,5, explanation
The Radix Stemonae, avicularin, bergenin compatibility using effect are more preferable.
Claims (10)
1. the extracting method of a Radix Stemonae extract, it is characterised in that preparation method is: take Fructus Sapindi Mukouossi, adds the water of 10 times of weight,
Soaking 0.5h, decoct 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice
Decoction liquor, being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, stand, mistake
Filter, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses microwave extracting, concentrates, and is dried,
Obtain Radix Stemonae extract.
The extracting method of Radix Stemonae extract the most according to claim 1, it is characterised in that microwave extracting described in preparation method
Method is: is put into by the concentrated solution after water extract-alcohol precipitation in microwave extracting apparatus and carries out microwave extracting, extracts power 400-600W, extraction
Taking 2 times, each 4-8 minute, amount is concentrated solution weight 2 times of 70% ethanol of addition, obtained extract every time, concentrated, preferably
Condition is: microwave extracting power 500W, every time extraction 6 minutes.
The extracting method of Radix Stemonae extract the most according to claim 1, it is characterised in that concentrate in said extracted method and use
Device, including concentrating cylinder, is arranged on the vaporizer of described concentration cylinder body bottom, is provided with at the top of described concentration cylinder and gives vent to anger
Hole and condensation panel, be provided with cooling liquid storage chamber in described condensation panel, be provided with described at the top of described concentration cylinder
Cooling liquid stores feed tube and the discharge pipe that chamber is connected, it is characterised in that: the roof in described concentration cylinder is provided with downwards
The swingle extended, described swingle is provided with scraper dish, and the web of described scraper dish connects with the inwall concentrating cylinder
Touching, be provided with lift cylinder on the roof of described concentration cylinder, the top of described swingle is through the roof of described concentration cylinder
And top is connected with described lift cylinder, in described swingle, it is provided with electric rotating machine, the main shaft of described electric rotating machine and institute
The center stating scraper dish is connected, and is additionally provided with the elevating lever through roof at the top of described concentration cylinder, in described lifting
The bottom of bar is provided with horn-like suction and steeps mouth, is provided with logical with the suction bubble that described horn-like suction bubble mouth is connected in described elevating lever
Road, is provided with the absorption pump housing at the top of described elevating lever, is provided with tune between the roof and described elevating lever of described concentration cylinder
Displacements of cylinders, described elevating lever does lifting moving under the effect of described regulation cylinder in described concentration cylinder.
The extracting method of Radix Stemonae extract the most according to claim 3, it is characterised in that enrichment facility in said extracted method
The sidewall of described concentration cylinder is provided with observation window, is provided with seal glass in described observation window, and described scraper dish is annulus
Shape, identical with the internal diameter concentrating cylinder and scraper dish the inner ring surface of the external diameter of described scraper dish passes through dowel bar and rotation
The main shaft of motor is connected, and described vaporizer is columnar structured, and described vaporizer is connected to concentrate cylinder by adpting flange
Diapire, in described vaporizer, be provided with evaporation tube, the sidewall of described vaporizer be provided with and be connected with described evaporation tube
Steam inlet and steam (vapor) outlet.
The extracting method of Radix Stemonae extract the most according to claim 1, it is characterised in that be dried in said extracted method and use
Device, the air quantity conditioning chamber being connected with described hothouse including hothouse, the roof of described hothouse is provided with charging
Mouthful, it is provided with discharging opening in the bottom of described hothouse, described air quantity conditioning chamber is provided with air intake passage, on described hothouse
It is provided with air exhaust passage, it is characterised in that: between described air quantity conditioning chamber and described hothouse, it is provided with dividing plate, on described dividing plate
Being uniformly provided with pore, be additionally provided with the cavity of lateral opening on described dividing plate, described cavity is arranged on the side by hothouse,
It is provided with electric rotating machine in described cavity, is additionally provided with the swingle being connected with described electric rotating machine main shaft, at described swingle
Surface is provided with upset paddle, and described swingle stretches in described hothouse, is provided with air guide channel at the center of described swingle,
Being uniformly provided with the hot gas injection jets being connected with described air guide channel on described upset paddle, the end of described swingle is stretched into
During described wind in conditioning chamber, in described air guide channel, it is provided with heat conduction blower fan, is provided with movable plate when described wind in conditioning chamber,
The side of described movable plate is provided with described pore matches air quantity adjusting plug and being arranged between adjacent air quantity adjusting plug
Air holes, is provided with mobile regulation cylinder between the sidewall of described movable plate and described air quantity conditioning chamber.
The extracting method of Radix Stemonae extract the most according to claim 5, it is characterised in that be dried in said extracted method and use
Described in device, the roof of described air quantity conditioning chamber is provided with chute, and the diapire at described air quantity conditioning chamber is provided with shifting chute, described shifting
Dynamic groove is consistent with the trend of described chute, and the top of described movable plate is movably arranged in described chute by scroll wheel, described
The bottom of movable plate is movably arranged in described shifting chute by movable block, and described mobile regulation cylinder is arranged on described movable block
And between the end wall of shifting chute.
The extracting method of Radix Stemonae extract the most according to claim 5, it is characterised in that be dried in said extracted method and use
The main shaft of electric rotating machine described in device is provided with driving fluted disc, is provided with mutually ratcheting with described driving fluted disc on described swingle
Teeth groove, the opening part of described cavity is provided with protection network, and described swingle is arranged through described protection network.
8. an infant detergent, it is characterised in that by the Radix Stemonae extract prepared in claim 1, avicularin, tiger
Auricled Hedyotis Herb element forms.
Infant detergent the most according to claim 8, it is characterised in that Radix Stemonae extract, avicularin, the weight of bergenin
Amount ratio is 8-12:4-6:5-7.
Infant detergent the most according to claim 9, it is characterised in that Radix Stemonae extract, avicularin, the weight of bergenin
Amount ratio is 10:5:6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610604773.XA CN106244356A (en) | 2016-07-28 | 2016-07-28 | A kind of infant detergent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610604773.XA CN106244356A (en) | 2016-07-28 | 2016-07-28 | A kind of infant detergent |
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| CN106244356A true CN106244356A (en) | 2016-12-21 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002003900A (en) * | 2000-06-22 | 2002-01-09 | Sunstar Eng Inc | Powder detergent composition for clothing |
| CN103735960A (en) * | 2013-12-10 | 2014-04-23 | 济南新起点医药科技有限公司 | Application of boenninghausenia sessilicarpa cough-asthma tablet to prepare medicaments for inhibiting lung cancer cell LLC proliferation |
| CN105602751A (en) * | 2016-03-14 | 2016-05-25 | 太仓棨淂服装有限公司 | Traditional Chinese medicine laundry detergent for infant clothes and preparation method thereof |
| KR101624951B1 (en) * | 2013-02-26 | 2016-05-30 | 청산화학(주) | Detergent composition for clothes comprising rhus verniciflua extract |
-
2016
- 2016-07-28 CN CN201610604773.XA patent/CN106244356A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002003900A (en) * | 2000-06-22 | 2002-01-09 | Sunstar Eng Inc | Powder detergent composition for clothing |
| KR101624951B1 (en) * | 2013-02-26 | 2016-05-30 | 청산화학(주) | Detergent composition for clothes comprising rhus verniciflua extract |
| CN103735960A (en) * | 2013-12-10 | 2014-04-23 | 济南新起点医药科技有限公司 | Application of boenninghausenia sessilicarpa cough-asthma tablet to prepare medicaments for inhibiting lung cancer cell LLC proliferation |
| CN105602751A (en) * | 2016-03-14 | 2016-05-25 | 太仓棨淂服装有限公司 | Traditional Chinese medicine laundry detergent for infant clothes and preparation method thereof |
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| 柯铭清 等主编: "《医院制剂》", 30 September 1980 * |
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