CN106237213A - A kind of pill medicine treating depression and preparation method thereof - Google Patents

A kind of pill medicine treating depression and preparation method thereof Download PDF

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Publication number
CN106237213A
CN106237213A CN201610808059.2A CN201610808059A CN106237213A CN 106237213 A CN106237213 A CN 106237213A CN 201610808059 A CN201610808059 A CN 201610808059A CN 106237213 A CN106237213 A CN 106237213A
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medicine
depression
fructus
radix
treating
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孙素蓉
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to technical field of Chinese medicine, purpose is a kind of pill medicine treating depression according to the traditional Chinese medical science, depression being recognized mechanism and providing, and each component of described medicine and mass parts ratio thereof are as follows: Fructus Alpiniae Oxyphyllae 5～15g, Fructus Jujubae 15～32g, Radix Ophiopogonis 6～16g, the Rhizoma Atractylodis Macrocephalae 8～16g, Semen Cuscutae (salt stir-fry) 9～16g, the Radix Astragali 15～28g, Flos Chrysanthemi 10～25g, Semen Cassiae 9～16g, Flos Buddlejae 6～16g, Yellow Fructus Gardeniae 10～20g, Radix Glycyrrhizae 3～12g；The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of pill medicine treating depression and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of pill medicine treating depression, particularly for pressing down The field of the pill medicine that strongly fragrant disease patient uses and preparation method thereof.
Background technology
Depression is also known as depressive disorder, low as main clinical characteristics with notable and lasting mental state, is mood disorders Main Types.Clinical visible mental state is low unbecoming with its situation, and the downhearted of emotion can be from depressed to extremely grieved, certainly Inferior depression, the most pessimistic and worldweary, can there be suicidal attempt or behavior；Even occur numb；Some cases has obvious anxiety and fortune Dynamic property is intense；Severe patient may occur in which the psychotic symptoms such as hallucination, vain hope.Even outbreak continues at least 2 weeks more than, elder every time Several years, majority of cases has the tendency of recurrent exerbation, and outbreak great majority can be alleviated every time, and part can have residual symptoms or transfer to slow Property.
So, just how to find a kind of medicine that can effectively treat above-mentioned depression, be that we are badly in need of to be solved at present Problem.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment depression, people gradually appreciate Chinese traditional treatment The advantage of above-mentioned depression, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, press down for existing western medical treatment is above-mentioned The present situation of strongly fragrant disease, it is an object of the invention to be to provide a kind of pill medicine treating depression, to solve patients with depression early Day restorative problem.This medicine is with common Chinese medicine as raw material, has instant effect, the feature such as evident in efficacy, and can have Effect treats above-mentioned depression.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide a kind of ball treating depression Agent medicine and preparation method thereof, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Fructus Alpiniae Oxyphyllae 5～15g, Fructus Jujubae 15～32g, Radix Ophiopogonis 6～16g, the Rhizoma Atractylodis Macrocephalae 8～16g, Semen Cuscutae (salt stir-fry) 9～16g, the Radix Astragali 15～ 28g, Flos Chrysanthemi 10～25g, Semen Cassiae 9～16g, Flos Buddlejae 6～16g, Yellow Fructus Gardeniae 10～20g, Radix Glycyrrhizae 3～12g.
A kind of pill medicine treating depression and preparation method thereof, it is characterised in that each component of described medicine and Its mass parts ratio is as follows:
Fructus Alpiniae Oxyphyllae 10～13g, Fructus Jujubae 18～28g, Radix Ophiopogonis 10～14g, the Rhizoma Atractylodis Macrocephalae 10～14g, Semen Cuscutae (salt stir-fry) 10～14g, the Radix Astragali 18～25g, Flos Chrysanthemi 15～22g, Semen Cassiae 10～14g, Flos Buddlejae 10～14g, Yellow Fructus Gardeniae 12～17g, Radix Glycyrrhizae 8～11g.
A kind of pill medicine treating depression and preparation method thereof, it is characterised in that the medicine of described " preferred plan " Each component and mass parts ratio as follows:
Fructus Alpiniae Oxyphyllae 12g, Fructus Jujubae 25g, 13g Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae 13g, Semen Cuscutae (salt stir-fry) 13g, Radix Astragali 22g, Flos Chrysanthemi 20g, Semen Cassiae 13g, Flos Buddlejae 13g, Yellow Fructus Gardeniae 15g, Radix Glycyrrhizae 10g.
A kind of pill medicine treating depression and preparation method thereof, it is characterised in that described method comprises the steps It is prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be ground into superfine end according to mass parts ratio stand-by；
B, the method preparing Chinese kmedicine bolus agent according to tradition, after being sieved by ground superfine myrrh thing, put in medicine device and mix Mixing all, (granularity of its watered pill is: 4.7mm-4.9mm), and then dry, sealed packaging to be then prepared as watered pill.
A kind of pill medicine treating depression and preparation method thereof, it is characterised in that described instructions of taking is: will preparation Good watered pill medicine is taken with every twice-daily, sooner or later services once, and dosage 2.5g/time, taking medicine before meal (warm water is sent down), Taking medicine 21～85 days, symptom gradually alleviates or fully recovers.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Fructus Alpiniae Oxyphyllae, nature and flavor: warm in nature, acrid in the mouth, have and warming spleen and stopping diarrha take the photograph saliva, effect of warming the kidney controlling nocturnal emission with astringent drugs reducing urination, be used for treating spleen-cold syndrome have loose bowels, The disease such as cold type of pain, the many salivas of mouth, the kidney enuresis, frequent micturition, seminal emission candle in vain in abdomen；
Fructus Jujubae, nature and flavor: sweet, warm, there is spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, tune Ying Wei, effect of solution poison of drug, be used for treating insufficiency of stomach food Less, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation；
Radix Ophiopogonis, nature and flavor: hardship sweet, micro-is slightly cold, there is nourishing YIN and moistening the lung, effect that stomach reinforcing clears away heart-fire, be used for treating lung-dryness syndrome due to deficiency of YIN, dry cough expectorant The diseases such as thick, chronic cough is spat blood, Tianjin few insomnia thirsty, vexed, dryness of the intestine constipation；
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter sweet, warm, have spleen reinforcing, stomach reinforcing, dampness and in, antiabortive effect, for treatment control deficient QI of the spleen and stomach, Anorexia, asthenia few gas, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea are uneasy Disease；
Semen Cuscutae (salt stir-fry), nature and flavor: warm, sweet, there is nourishing the liver and kidney, antiabortive, improving eyesight, effect of antidiarrheal, it is used for treating sexual impotence and loses Essence, dripping urination, enuresis frequent micturition, medicine knees soreness, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen are suffered from a deficiency of the kidney and are rushed down, externally treating leucoderma；
The Radix Astragali, nature and flavor: sweet, tepor, there is polishing consolidating superficial resistance, effect of torr skin ulcer granulation promoting, be used for treating body void spontaneous perspiration, chronic diarrhea, proctoptosis, The diseases such as impractical swollen, the chronic ulcer of uterine prolapse, chronic nephritis, body, the long disunion of the open sore part；
Flos Chrysanthemi, nature and flavor: Huang pungent, sweet, bitter, micro-, there is effect of dispelling wind, heat clearing away, improving eyesight, removing toxic substances, be used for treating headache, dizziness, The diseases such as conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling；
Semen Cassiae, nature and flavor: salty hardship, Pingliang, nontoxic, there is effect of expelling wind and clearing away heat, detoxification and promoting urination, be used for treating anemopyretic cold, The diseases such as influenza, acute conjunctivitis, jaundice due to damp-heat, acute and chronic nephritis, leukorrhagia, scrofula, carbuncle sore furuncle and phyma, mastitis；
Flos Buddlejae, nature and flavor: sweet, cool, have dispel the wind, removing heat from blood, profit liver, effect of improving eyesight, be used for treating conjunctival congestion and swelling pain, many tear shy The diseases such as bright, optic atrohic blindness cataracta, the wind rotten eye of string；
Yellow Fructus Gardeniae, nature and flavor: bitter, cold, there is effect of heat clearing away, pathogenic fire purging, removing heat from blood, be used for treating calentura restlessness of asrhenia type and insomnia, jaundice, pouring Sick, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache；
Radix Glycyrrhizae, nature and flavor: sweet, flat, have and middle emergency, lung moistening, removing toxic substances, effect of coordinating the actions of various ingredients in a prescription, be used for treating weakness of the spleen and stomach, food Less, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, give birth to, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores, Solve poison of drug and alimentary toxicosis.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment depression and the dialectical principle combined, from pharmacological action and work Think by mechanism: with regard to depression, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has above-mentioned disease very well Therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned depression and a kind of Chinese medicine formula of proposing, uses medicine prepared by this formula Thing good drug efficacy, instant effect, it is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Tool below in conjunction with the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of pill medicine treating depression, it is characterised in that each component of described medicine and mass parts thereof are than following institute Show:
Fructus Alpiniae Oxyphyllae 12g, Fructus Jujubae 25g, 13g Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae 13g, Semen Cuscutae (salt stir-fry) 13g, Radix Astragali 22g, Flos Chrysanthemi 20g, Semen Cassiae 13g, Flos Buddlejae 13g, Yellow Fructus Gardeniae 15g, Radix Glycyrrhizae 10g.
Embodiment 2:
A kind of pill medicine treating depression, it is characterised in that each component of described medicine and mass parts thereof are than following institute Show:
Fructus Alpiniae Oxyphyllae 13g, Fructus Jujubae 28g, 14g Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae 14g, Semen Cuscutae (salt stir-fry) 14g, Radix Astragali 25g, Flos Chrysanthemi 22g, Semen Cassiae 14g, Flos Buddlejae 14g, Yellow Fructus Gardeniae 17g, Radix Glycyrrhizae 11g.
Embodiment 3:
A kind of pill medicine treating depression, it is characterised in that each component of described medicine and mass parts thereof are than following institute Show:
Fructus Alpiniae Oxyphyllae 15g, Fructus Jujubae 32g, 16g Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae 16g, Semen Cuscutae (salt stir-fry) 16g, Radix Astragali 28g, Flos Chrysanthemi 25g, Semen Cassiae 16g, Flos Buddlejae 16g, Yellow Fructus Gardeniae 20g, Radix Glycyrrhizae 12g.
Model case:
Through clinical conditions patients with depression totally 167 example, the age is 100 examples of more than 25 years old, and only 67 examples are less than 25 years old. 90 examples of recovery from illness in 167 example patients, 77 effective examples, total effective rate reaches 100%.After treatment, symptom gradually alleviates or fully recovers.

Claims (3)

1. the pill medicine treating depression, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows Shown in:
Fructus Alpiniae Oxyphyllae 5～15g, Fructus Jujubae 15～32g, Radix Ophiopogonis 6～16g, the Rhizoma Atractylodis Macrocephalae 8～16g, Semen Cuscutae (salt stir-fry) 9～16g, the Radix Astragali 15～ 28g, Flos Chrysanthemi 10～25g, Semen Cassiae 9～16g, Flos Buddlejae 6～16g, Yellow Fructus Gardeniae 10～20g, Radix Glycyrrhizae 3～12g.
The pill medicine for the treatment of depression the most according to claim 1, it is characterised in that each component of described medicine and Its mass parts ratio is as follows:
Fructus Alpiniae Oxyphyllae 10～13g, Fructus Jujubae 18～28g, Radix Ophiopogonis 10～14g, the Rhizoma Atractylodis Macrocephalae 10～14g, Semen Cuscutae (salt stir-fry) 10～14g, the Radix Astragali 18～25g, Flos Chrysanthemi 15～22g, Semen Cassiae 10～14g, Flos Buddlejae 10～14g, Yellow Fructus Gardeniae 12～17g, Radix Glycyrrhizae 8～11g.
3. according to the pill medicine of the treatment depression described in claim 1 to 2, it is characterised in that each group of described medicine Divide and mass parts ratio be as follows:
Fructus Alpiniae Oxyphyllae 12g, Fructus Jujubae 25g, 13g Radix Ophiopogonis, Rhizoma Atractylodis Macrocephalae 13g, Semen Cuscutae (salt stir-fry) 13g, Radix Astragali 22g, Flos Chrysanthemi 20g, Semen Cassiae 13g, Flos Buddlejae 13g, Yellow Fructus Gardeniae 15g, Radix Glycyrrhizae 10g.
CN201610808059.2A 2016-09-08 2016-09-08 A kind of pill medicine treating depression and preparation method thereof Withdrawn CN106237213A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860816A (en) * 2017-03-24 2017-06-20 成都海青生物科技有限公司 A kind of Chinese medicine composition for treating depression and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860816A (en) * 2017-03-24 2017-06-20 成都海青生物科技有限公司 A kind of Chinese medicine composition for treating depression and preparation method thereof

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Application publication date: 20161221