CN106236333A - The artificial vertebral body of a kind of road nail pedicle fix in the past and location and installation instrument - Google Patents

The artificial vertebral body of a kind of road nail pedicle fix in the past and location and installation instrument Download PDF

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Publication number
CN106236333A
CN106236333A CN201610869458.XA CN201610869458A CN106236333A CN 106236333 A CN106236333 A CN 106236333A CN 201610869458 A CN201610869458 A CN 201610869458A CN 106236333 A CN106236333 A CN 106236333A
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China
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vertebral body
pedicle
screw
artificial
nail
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CN201610869458.XA
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CN106236333B (en
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董谢平
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Jiangxi Provincial Peoples Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30942Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

The artificial vertebral body of a kind of road nail pedicle fix in the past and location and installation instrument, is characterized in that with pedicle screw fixing hole on artificial vertebral body, can accurately guide screw to be fixed on by artificial vertebral body in the pedicle of vertebral arch of both sides, it is achieved strong self-stabilization.Steel plate also can be incorporated artificial vertebral body by this artificial vertebral body as required, steel plate can upper and lower side all beyond the length of artificial vertebral body, it is possible to only upper end is longer than artificial vertebral body.Steel plate grows end and also can be provided with the screw hole coaxial with pedicle of vertebral arch and point to the screw hole of vertebral body.For inserting front road pedicle nail with ensureing safety and precise, it is simultaneously provided with boring positioning guide plate and osteotomy guide plate.Described artificial vertebral body and the installation tool such as boring, osteotomy guide plate thereof are all based on medical image data, utilize 3D printing technique to design and print.Safely and quickly can realize the maximization of the fixing intensity of front road spinal stability operation.

Description

The artificial vertebral body of a kind of road nail pedicle fix in the past and location and installation instrument
Technical field
The invention belongs to medical instruments field, the artificial vertebral body of especially a kind of road nail pedicle fix in the past and location peace Holding tool.
Background technology
Need line stabilization type reconstruction operations after the excision of the pathological changes such as Cervical vertebral tumor, tuberculosis, wound, the most generally use autologous bone or Allograph bone or artificial bone or titanium net or artificial vertebral body are supported at defect, then by lock screw by Interal fixation in retaining Vertebral body on.But it is all spongy bone due to vertebral body, and anteroposterior diameter is shorter, be only capable of using the screw of about 15mm.Therefore fixing strong Spend more weak, need to cervical region brace carry out up to several months fixing.The especially vertebral body in screw set itself also has pathological changes or weight Building the case that sections is longer, its fixation is more weak, spinal column displacement, nonunion, steel plate screw and implantation caused by solid failure Thing loosens the complication such as dislocation fracture and happens occasionally.Such as tuberculosis of spine, typically occurs in intervertebral disc and upper and lower vertebral rim, The top of upper vertebral body is relative with the bottom sclerotin of the next vertebral body complete, is available for screw and fixes, but sclerotin at this is normal on MRI Being infiltrated, the spongy bone of vertebral body will become more crisp, rely solely on 2 pieces of vertebral body nails and is difficult to obtain stable fixing, strengthen What bed knife will make pathological changes vertebral body cuts full resection operation, then must be excised in the lump by the intervertebral disc of upper and lower side and plant to provide Bone bed, merges thereon for the supporter implanted, so increases fixed-segment, decrease the range of activity of cervical vertebra, the most more It is susceptible to the regression of adjacent segment.For another example, long segment Cervical vertebral tumor need to be by whole to all pathological changes vertebral bodys and upper and lower intervertebral disc thereof Excision, after supporting with titanium net or artificial vertebral body, two pieces of vertebral body nails each can only be played in steel plate two ends, and cannot use at the vertebral body excised Screw is reinforced, and long to the span making steel plate, fixing intensity weakens naturally.Meropodium degree cervical spinal trauma Hang Qian road is fixing in subtracting titanium net After equally exist the problems referred to above.
For solving this problem, in recent years occur in that the research of front road cervical pedicle screws technique for fixing, i.e. from vertebral body front to The strongest pedicle of vertebral arch of vertebra penetrates the screw beyond vertebral body one times of multiple-length of nail and is fixed.Basic research shows, it is fixed Intensity promotes at double.But owing to conical surface lacks the anatomic landmark being available for positioning, during putting nail, easily accidentally injure vertebral artery, ridge The important feature such as marrow or nerve root;In addition screw is relatively big with the angle of cut of steel plate, and lock screw tail end Chang Huigao is convex on steel plate, Withstand on esophagus rear wall, the wriggling hindering esophagus pharynx to produce, cause esophagus rear wall congestion and edema, and then cause esophagus fistula.Above-mentioned Complication all can cause the most serious consequence such as life danger or high paraplegia.Additionally, due to pedicle of cervical vertebra axis and cervical vertebra The sagittal line angle of cut is excessive, and two pieces of pedicle nail tail ends of same vertebral body will intersect.Therefore only a few is only had the most both at home and abroad special Family reports the clinical case of anterior approach vertebral arch nail, and is single piece of screw and fixes.Spine dieases equally exists above-mentioned asking Topic.
Summary of the invention
Fixing intensity this difficult problem more weak for solving anterior spinal, the present invention devises road nail pedicle fix before one Artificial vertebral body, and auxiliary positioning install operation tool.
For realizing the purpose of the present invention, the technical solution adopted in the present invention is:
Medical image data and 3D printing technique is utilized to set up the mathematical model of pathological changes spinal column, according to illness analysis, on model Make the planning of pathological changes excision extension, and virtual resection pathological changes, the position of the most virtual adjustment and recovery spinal column, make vertebral levels, Curvatures etc. recover the optimum state can being remedied to art.Further according to the situation of Cranial defect under this state, design and fill up scarce Damage, support the artificial vertebral body of spinal column, or plus and in order to the steel plate of spinal fixation.The present invention artificial vertebral body and steel plate can be melted for Integrally, steel plate is the antetheca of artificial vertebral body.Preferably, described steel plate can be slightly longer than artificial vertebral body in two ends, it is possible to only upper end is long In artificial vertebral body.The two ends exceeding artificial vertebral body at steel plate are respectively arranged with several screw holes.Preferably, described screw hole can be with Pedicle of vertebral arch is coaxial, it is also possible to be that non-accurate orientation points to vertebral body, or a combination of both.Preferably, artificial vertebral body part The fixing nail that the pedicle of vertebral arch of all vertebral bodys also designed and excised is coaxial, and all vertebral bodys all can design two vertebral arch Root follows closely fixing hole, that is all vertebral bodys all can carry out bilateral front road nail pedicle fix.Therefore, its fixing intensity is up to maximum Change.
For ensureing pathological changes vertebral resection, original body surface symbol disappearance, described artificial vertebral body remains to after implanting at Cranial defect Pedicle nail fixing hole precisely implants pedicle screw, present invention additionally comprises the pediculus arcus vertebrae boring utilizing original surface of bone to make and leads Plate and osteotomy guide plate.Preferably, described boring guide plate with in operative region when modeling the still fine and close smooth surface of bone in surface for covering Version, makes the boring guide pipe of projection on outer surface each pedicle of vertebral arch major axis extended line;Upper two pedicles of vertebral arch of same vertebral body are led Can intersect to the substrate of pipe, two guide pipe interior lumen also can intersect.The masking-out of described osteotomy guide plate is also by above-mentioned requirements Make, and produce the osteotomy guiding window of hollow out in the plane planning osteotomy.Can be carried out in advance by described boring guide plate Front road bilateral pediculus arcus vertebrae boring, outputs pedicle screw trajectory;Using osteotomy guide plate instead, then to carry out the pathological changes of accurate scope according to plan clear Removing, after implantable artificial vertebral body, the pedicle screw trajectory got out is detected in nail pedicle fix hole printed on it, can test Whether card artificial vertebral body disposes accurate, and puts artificial vertebral body according in type pedicle screw trajectory and be finely adjusted, it is achieved Precisely, safe, efficient front road pedicle screw fixation.
The artificial vertebral body gone out designed by the present invention and all guide plates are to use metal or nonmetal 3D based on 3D printing technique Printer manufactures, it is possible to realize the manufacture requirements of design.Especially implant can be printed as the imitative of concrete dynamic modulus edge encryption Raw trabecular bone structure, effectively prevents its depression and is beneficial to the fusion of itself and host bone.
The installation of the present invention also can be carried out under the navigation auxiliary with robot.
The invention has the beneficial effects as follows, can accurately customize out individuation, incidentally can to realize Selfstabilizing mechanism maximum The artificial vertebral body changed, and the anterior spinal pathological changes excision fixing intensity of stability reconstruction operation can be realized safely, quickly, accurately Maximization, realize the friendly of implant and tissue simultaneously and merge with steady in a long-term.
Accompanying drawing explanation
Fig. 1 is the rear side schematic view that the present invention adds cartridge screw;
Fig. 2 is the front side schematic view of the present invention;
Fig. 3 is that the present invention positions boring guide plate schematic diagram;
Fig. 4 is osteotomy guide plate schematic diagram of the present invention;
In figure:
1. vertebral body;2. steel plate;3. screw hole;4. nail pedicle fix hole;5. pedicle nail;6. vertebral body screw;7. boring guide plate Mask;8. guide pipe;9. osteotomy guide plate mask.
Detailed description of the invention
The present invention is further elaborated with embodiment below in conjunction with the accompanying drawings.
Artificial vertebral body of the present invention can be by vertebral body 1 and steel plate 2-in-1 become winged column, it is also possible to be simple Column.Vertebral body 1 is in hollow barrel, in order to fill autologous or allosome, bone-xenograft or artificial bone.Vertebral body 1 profile can be according to excision Pathological changes vertebral body and adjacent vertebral bodies flexible shapes set.If, its cross section can be circle, ellipse, rectangle, trapezoidal etc..
Preferably, the artificial vertebral body of described winged column pattern is close to vertebral body 1 antetheca by steel plate 2, and melt therewith for One composition, to thicken antetheca.Steel plate 2 length is more than vertebral body 1 length.Can be that two ends are all beyond the double-vane post at vertebral body 1 edge Shape;Can also be that upper end exceeds vertebral body 1, the single-blade column that lower end is concordant with vertebral body 1.Steel plate 2 two ends are each beyond the part of vertebral body 1 Several screw holes 3 are set, in order to cross screw, steel plate 2 are fixed on the vertebra vertebral body or pedicle of vertebral arch that vertebral body 1 supported.
Preferably, the screw hole 3 at described steel plate 2 two ends can be divided into pedicle of vertebral arch nail and vertebral body nail, pedicle of vertebral arch nail with Corresponding pedicle of vertebral arch is coaxial, and pedicle screw 5 and is fixed thereon through the pedicle of vertebral arch longitudinal axis through this hole;The axis of vertebral body nail Pointing to vertebral body rear, vertebral body screw 6 is screwed in vertebral body through this hole.
Preferably, described vertebral body 1 and steel plate 2 length are all in accordance with needing the vertebra quantity of resection and the most full vertebral resection Need to decide etc. the state of an illness, but artificial vertebral body is equipped with vertebral arch corresponding on each vertebra both sides pedicle of vertebral arch axis having excised vertebral body Root nail fixing hole 4, runs through vertebral body 1 front and rear wall;Each fixing hole 4 all in single-stage ladder tubulose, is followed closely in order to accommodate pedicle screw 5 Head also prevents pedicle screw from sinking.For avoiding both sides pedicle screw 5 to collide, the relatively gross porosity road of fixing hole 4 tail end should be deepened To making pedicle screw 5 depression in the antetheca that vertebral body 1 has been pressurizeed thick.
The pedicle screw of the present invention adds to produce more greatly by threaded rivet nut and relatively shaft diameter with vertebral body screw Press system also prevents the nail head of screw depression to be grouped into, and ailhead is short and small, ailhead shape only allow its after being screwed into screw hole with Steel plate 2 is concordant, or slightly above steel plate 2 surface and must be smooth dimpling shape.Screw hole 3 can be to rotate with the combination of screw Plain screw structure with beat, it is also possible to be locked out structure.
Present invention additionally comprises the pediculus arcus vertebrae boring guide plate and osteotomy guide plate utilizing original surface of bone to make.Preferably, described brill Hole guide plate with in operative region when modeling the still fine and close smooth surface of bone in surface for boring guide plate masking-out 7, boring guide plate masking-out 7 Inner surface coincide with the bony structure outer surface fitted, and boring guide plate masking-out 7 pressing can not occur any after being stuck on surface of bone The fine motion in direction.Outer surface in boring guide plate masking-out 7 makes and boring guide plate masking-out 7 Rhizoma Nelumbinis along each pedicle of vertebral arch major axis extended line The boring guide pipe 8 closed, described guide pipe 8 can retrain drill bit and can only advance along its longitudinal axis, i.e. can only advance along the pedicle of vertebral arch longitudinal axis, Pedicle screw trajectory is outputed accurately with this;The substrate of upper two the pediculus arcus vertebrae boring guide pipes 8 of same vertebral body can be intersected, and tube wall can To merge into each other, its interior lumen also can intersect.
The osteotomy guide plate masking-out 9 of described osteotomy guide plate is also made by above-mentioned requirements, and produces in the plane planning osteotomy The osteotomy of hollow out guides window, and window edge is osteotomy guide surface 10.
Front road bilateral pediculus arcus vertebrae boring can be carried out in advance by described boring guide plate, output pedicle screw trajectory;Use instead and cut Bone conduction plate then can be carried out scope pathological changes accurately according to plan and remove.In defect after removing pathological changes after implantable artificial vertebral body, warp The pedicle screw trajectory got out is detected in nail pedicle fix hole 5 printed on it, can verify whether artificial vertebral body disposes Accurately, and according in type pedicle screw trajectory artificial vertebral body put and be finely adjusted, thus realize precisely, safely, quickly Front road pedicle screw fix.

Claims (10)

1. the artificial vertebral body of road nail pedicle fix and a location and installation instrument before, it is characterized in that artificial vertebral body has can be with Front road pedicle screw is fixed in the fixing hole in the pedicle of vertebral arch of cut vertebral body place vertebra, and has auxiliary to output vertebral arch The location drilling guide device in Gen Ding road and auxiliary precisely excise the osteotomy guider of pathological changes vertebral body.
2. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of Being that artificial vertebral body is hollow column, its cross section can be circular, oval, rectangle or trapezoidal;It corresponds to both sides vertebral arch Being provided with the pedicle screw fixing hole running through front and rear wall at root axis, each fixing hole is all in single-stage ladder tubulose, in order to accommodate Pedicle screw ailhead also prevents pedicle screw from sinking;For avoiding the collision of both sides pedicle screws, fixing hole tail end thicker Duct should add and is deep to make pedicle screw depression in vertebral body antetheca;Pedicle screw fixed hole is screwed into screw can be by artificial Vertebral body is fixed in pedicle of vertebral arch.
3. artificial vertebral body described in can be by the winged column of vertebral body and steel plate synthesis, and vertebral body antetheca is close to by steel plate, and with The composition that combines together, to thicken antetheca.
4. the artificial vertebral body of road nail pedicle fix and location and installation instrument before a kind of as described in claim 1 or 3, it is special Levying and be that steel plate length is more than vertebral body length, its shape can be that two ends are all beyond the double-vane column of vertebral rim, it is also possible to is Upper end exceeds vertebral body, the single-blade column that lower end is concordant with vertebral body.
5. the artificial vertebral body of road nail pedicle fix and location and installation instrument before a kind of as described in claim 1 or 3, it is special Levy and be that steel plate two ends respectively arrange several screw holes, in order to cross screw, by Interal fixation in vertebral body beyond the part of vertebral body On the vertebra vertebral body supported or pedicle of vertebral arch;The screw hole at described steel plate two ends can be divided into pedicle of vertebral arch nail and vertebral body nail, vertebra Nut nail is coaxial with corresponding pedicle of vertebral arch, and pedicle screw and is fixed thereon through the pedicle of vertebral arch longitudinal axis through this hole;Vertebral body The axis of nail points to vertebral body rear, and vertebral body screw is screwed in vertebral body through this hole.
6. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of It is that pedicle screw and vertebral body screw are bigger to produce pressurizing mechanism and to prevent spiral shell by threaded rivet nut and relatively shaft diameter The nail head of nail depression is grouped into, and ailhead is short and small, and ailhead shape only allows it concordant with steel plate after being screwed into screw hole or slightly higher In surface of steel plate and must be smooth dimpling shape;Screw hole can be to rotate the plain screw knot with beat with the combination of screw Structure, it is also possible to be locked out structure.
7. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of Be described boring to device with in operative region when modeling the still fine and close smooth surface of bone in surface for boring guide plate masking-out, masking-out Inner surface coincide with the bony structure outer surface fitted, masking-out pressing can not occur the micro-of any direction after being stuck on surface of bone Dynamic;Outer surface in masking-out makes the boring guide pipe closed with masking-out Rhizoma Nelumbinis, described guide pipe along each pedicle of vertebral arch major axis extended line Drill bit can be retrained can only advance along its longitudinal axis.
8. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of Be described osteotomy guider with in operative region when modeling the still fine and close smooth surface of bone in surface for osteotomy guide plate masking-out, cover The inner surface of version coincide with the bony structure outer surface fitted, and masking-out pressing can not occur any direction after being stuck on surface of bone Fine motion;Plane in plan osteotomy is produced the osteotomy of hollow out and is guided window, and window edge is osteotomy and guides face into.
9. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of It is that described artificial vertebral body, drilling guide device, osteotomy guider are to utilize medical image data and the design of 3D printing technique With manufacture.
10. the artificial vertebral body of road nail pedicle fix and location and installation instrument, its feature before as claimed in claim 1 a kind of It is that artificial vertebral body uses the 3D print structure of concrete dynamic modulus edge encryption, to meet body biomechanics requirement.
CN201610869458.XA 2016-10-01 2016-10-01 Artificial vertebral body fixed by anterior pedicle screw and positioning and installing tool Active CN106236333B (en)

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Cited By (7)

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CN106923941A (en) * 2017-04-26 2017-07-07 中国人民解放军第二军医大学第二附属医院 A kind of personalized plate body integration artificial vertebral body based on 3D printing
CN106943215A (en) * 2017-04-25 2017-07-14 中国人民解放军第二军医大学第二附属医院 A kind of adjustable assembly type artificial vertebral body
CN107095730A (en) * 2017-04-25 2017-08-29 中国人民解放军第二军医大学第二附属医院 A kind of assembly type artificial vertebral body
CN108324409A (en) * 2018-01-08 2018-07-27 北京爱康宜诚医疗器材有限公司 Bone attachment device
CN108542556A (en) * 2018-04-28 2018-09-18 北京爱康宜诚医疗器材有限公司 Waist sacrum artificial prosthesis
CN109009581A (en) * 2018-09-13 2018-12-18 陕西东望科技有限公司 A kind of assembly type artificial vertebral body
CN109646153A (en) * 2019-02-28 2019-04-19 赵刘军 Novel interbody cage systems based on lower cervical anterior pedicle of vertebral arch basal part screw

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