CN106234771A - A kind of feed additive, its application and a kind of feedstuff - Google Patents
A kind of feed additive, its application and a kind of feedstuff Download PDFInfo
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- CN106234771A CN106234771A CN201610608467.3A CN201610608467A CN106234771A CN 106234771 A CN106234771 A CN 106234771A CN 201610608467 A CN201610608467 A CN 201610608467A CN 106234771 A CN106234771 A CN 106234771A
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Abstract
This application provides a kind of feed additive, it include in the ester of high fatty alcohol and high fatty alcohol one or both, present invention also provides feed additive and have the application on the viral feedstuff of cyst membrane in preparation preventing and treating, present invention also provides a kind of feedstuff including above-mentioned feed additive.The feed additive of the application includes high triacontanol and the ester thereof that toxicity is the lowest, it has preferable prevention effect to the virus having cyst membrane, it it is the feed additive of the most non-specific a kind of preventing and treating animal virus, both need not to put into any artificial, also animal will not be caused stress and affect growth of animal, and, also can promote growth of animal.Result of the test shows, the cultivated animals disaster infections loss that can make of feed additive of the present invention reduces at least 50%.
Description
Technical field
The present invention relates to field of feed, particularly relate to a kind of feed additive, its application and a kind of feedstuff.
Background technology
Along with development and the deterioration of environment of society, various viruses are constantly grown, cultivated animals and environment for human survival phase
With, therefore cultivated animals is constantly attacked by various viruses.In order to strengthen the management to cultivated animals, prevent, control and flutter
Go out animal epidemic, promotes aquaculture development, protects human health, safeguards public health security, take one for animal epidemic
The prophylactico-therapeutic measures of series.
The most commonly used prophylactico-therapeutic measures includes: vaccination, breeding environment a large amount of spray disinfectant agent and to cultivation
The animal population of field (specific region) is extinctive to be killed off and corpse carries out three kinds of methods of harmless treatment.Said method exist with
Lower pluses and minuses:
It is the commonly used effective ways of current animal feeding that cultivated animals carries out (weak poison) vaccination, and achieves huge
Big achievement.But this is a kind of specific immunity method, different virus must be led with corresponding weak poison low toxicity vaccination
Activating the thing different types of vaccine of n times to be inoculated in all one's life, even if same vaccine, needs that all one's life of animal has inoculate for several times,
Not only the workload of people is huge, and inoculates every time and all can cause Animal stress, affects growth of animal；On the other hand, due to disease
Poison variation happens occasionally and has the tendency of aggravation, frequently results in vaccination invalid, and animal virus has thousands of kinds, it is impossible to
All developing vaccine each virus and animal carries out immunity inoculation, therefore, the virus outbreak disease of non-immunity inoculation still can
Heavy loss and strike is caused to aquaculture.
Spray disinfectant agent a large amount of to breeding environment, just not saying the use cost of disinfectant, owing to disinfectant is to animal
Vitro is sterilized, and is at a complete loss as to what to do the animal contaminated, thus the quantity rescuing cultivated animals is extremely limited, and disinfectant
It is the most fearful that pollution on the environment is often, the particularly pollution to water body.
To pernicious potent virus sexually transmitted disease, the animal population of plant specific region is killed off Tu absolutely, and corpse is entered
Row harmless treatment, this is the pressure Disposal Measures of many countries.This measure causes catastrophic loss to breeding enterprise, has
If country to raiser (enterprise) compensating for loss and damage less time, many plants (enterprise) fallen ill then can conceal by every possible means
Epidemic situation, brings irretrievable loss often to region even this country.
Feedstuff is the food that growth of animal is indispensable, if the composition of preventing and treating animal virus is added to feedstuff, and can be real
The now effective preventing and treating to animal epidemic, and do not affect the growth of animal, therefore, research is a kind of harmless and prevention effect is preferably raised
Feed additives is the most necessary.
Summary of the invention
Present invention solves the technical problem that and be to provide a kind of feedstuff, the feed additive that the application provides is harmless and prevents and treats
Effect is preferable, further, can promote growth of animal.
In view of this, this application provides a kind of feed additive, in the ester including high fatty alcohol and high fatty alcohol
One or both.
Preferably, described high fatty alcohol include lauryl alcohol, tridecanol, myristyl alcohol, pentadecanol, hexadecanol, Heptadecyl alcohol,
Stearyl alcohol, nonadecanol, eicosanol, two undecyl alcohols, tadenan, tricosanol, tetracosanol, pentacosyl alcohol, hexacosyl alcohol,
One or more in heptacosanol, octacosanol, nonacosanol and melissyl alcohol.
Preferably, the ester of described high fatty alcohol obtains by being dehydrated after described high fatty alcohol and fatty acid esterification.
Preferably, described fatty acid is selected from formic acid, acetic acid, propanoic acid, butanoic acid, valeric acid, caproic acid, enanthic acid, octanoic acid, n-nonanoic acid, the last of the ten Heavenly stems
Acid, undecanoic acid, lauric acid, tridecanoic acid, myristic acid, pentadecanoic acid, palmitic acid, heptadecanoic acid, stearic acid, nonadecanoic acid, 20 acid, two
Undecanoic acid, behenic acid, tricosanic acid or behenic acid.
Present invention also provides the feed additive described in such scheme to have on the feedstuff of virus of cyst membrane in preparation preventing and treating
Application.
Preferably, the virus having cyst membrane described in includes:
A) alphavirus in Togaviridae, rubella virus genus, Arterivirus,
B) Flavivirus in flaviviridae, pestivirus, class Hepacivirus,
C) hat during hat closes shape Viraceae closes Tobamovirus, grand Tobamovirus,
D) equine influenza virus in orthomyxoviridae family, swine influenza virus, poultry Influenza Virus,
E) paramyxovirus genus in Paramyxoviridae, Morbillivirus,
F) Marburg virus in filamentous virus section, Ebola virus,
G) rabies virus in Rhabdoviridae, bovine ephemeral fever virus, vesicular stomatitis virus, Fish strong shape virus,
H) Bunyavirus in Bunyaviridae, phlebotomus fever virus genus, Nairovirus, Hanta virases,
I) lymphocytic choriomeningitis virus in arenvirus section, Lassa virus, Junin virus, Ma Xiubo
Virus,
J) the mammalian B retrovirus retrovirus in Retroviridae belongs to, mammal c-type retrovirus retrovirus belongs to, fowl C
Type retrovirus retrovirus genus, D type retrovirus retrovirus genus, bovine leucosis-people are addicted to T cell retrovirus retrovirus genus, lentivirus, foam disease
Poison belongs to,
K) orthopoxvirus in Poxviridae, Avipoxvirus, Capripoxvirus, rabbitpox virus genus, Suipoxvirus,
Parapoxvirus genus, Molluscipoxvirus, tooth tower Poxvirus,
L) pseudorabies virus in herpetoviridae, equine abortion virus, infectious bovine rhinotrachetis virus, cattle ulcer
Property mammilitis virus (attached) A Leidun virus, malignant catarrhal fever virus, procine inclusion body rhinitis virus, canine alphaherpesvirus, cat nose gas
Pipe inflammation virus, marek's disease virus, chicken infectivity throat trachea fire virus, duck plague virus,
M) Hepadnavirus in Hepadnaviridae, Avihepadnavirus,
N) iridescent virus in Iridoviridae, Chloriridovirus genus, Ranavirus, Lymphocystivirus, eka-gold
Fish virus 1 type Tobamovirus,
Or O) Bao Na disease virus in unfiled virus and African swine fever virus.
Present invention also provides a kind of feedstuff, including normal feedstuff and feed additive, described feed additive includes
High fatty alcohol described in such scheme and one or both in the ester of high fatty alcohol.
Preferably, one or both concentration in described feedstuff in the ester of described high fatty alcohol and high fatty alcohol
It is 1～25000mg/kg.
Preferably, described feedstuff include pig feed, cattle feedstuff, sheep feedstuff, chicken feed, duck feed, goose feedstuff, fish meal,
Shrimp feed, Eriocheir sinensis feedstuff, dog feed, cat feed, ermine feedstuff, deer feedstuff, turtle feed, trionyx sinensis feed, shellfish feedstuff, Monopteri albi feedstuff, Columba livia are raised
Material, quail feed, fodder for snake, horse feedstuff or donkey feedstuff.
This application provides a kind of feed additive, it include the one in the ester of high fatty alcohol and high fatty alcohol or
Two kinds, present invention also provides feed additive has the application in the virus of cyst membrane in preventing and treating, present invention also provides a kind of bag
Include the feedstuff of above-mentioned feed additive.The feed additive of the application includes high triacontanol and the ester thereof that toxicity is the lowest, and it is right
The phospholipid layer structure of zooblast is optimized, and can successfully prevent the invasion implantation of virus, virus is strangled in rudiment and
Commitment, is the method for the most non-specific a kind of preventing and treating animal virus, both need not to put into any artificial, also will not
Animal is caused stress and affect growth of animal, and, also can promote growth of animal.Result of the test shows, feedstuff of the present invention adds
The cultivated animals disaster infections loss that can make adding agent at least reduces 50%, endangers extremely serious fowl the most in recent years
Influenza is exactly the deadly infectious disease that a kind of people fowl having cyst membrane suffers from altogether, and the feed additive of the application is the most aobvious to its prevention effect
Write.
Detailed description of the invention
In order to be further appreciated by the present invention, below in conjunction with embodiment, the preferred embodiment of the invention is described, but
Should be appreciated that these describe simply as to further illustrate the features and advantages of the present invention rather than to the claims in the present invention
Limit.
The embodiment of the invention discloses a kind of feed additive, it includes in the ester of high fatty alcohol and high fatty alcohol
One or both.
Herein described feed additive includes one or both in the ester of high fatty alcohol and high fatty alcohol.Institute
State what high fatty alcohol was well known to those skilled in the art, this application is had no particular limits.Concrete, herein described
High fatty alcohol be preferably selected from lauryl alcohol, tridecanol, myristyl alcohol, pentadecanol, hexadecanol, Heptadecyl alcohol, stearyl alcohol, 19
Alcohol, eicosanol, two undecyl alcohols, tadenan, tricosanol, tetracosanol, pentacosyl alcohol, hexacosyl alcohol, heptacosanol, two
One or more in octadecanol, nonacosanol and melissyl alcohol；Preferably, herein described high fatty alcohol is 20
Dialkanol.The source of described high fatty alcohol is had no particular limits by the application, can be commercially available prod, it is also possible to by existing
Method prepares.
The ester of described high fatty alcohol is the ester corresponding to described high fatty alcohol, and its preparation method is according to art technology
Prepared by the mode known to personnel, example, and the ester of described high fatty alcohol is by described high fatty alcohol and fatty acid esterification
Rear dehydration obtains, and described fatty acid is preferably selected from formic acid, acetic acid, propanoic acid, butanoic acid, valeric acid, caproic acid, enanthic acid, octanoic acid, n-nonanoic acid, the last of the ten Heavenly stems
Acid, undecanoic acid, lauric acid, tridecanoic acid, myristic acid, pentadecanoic acid, palmitic acid, heptadecanoic acid, stearic acid, nonadecanoic acid, 20 acid, two
Undecanoic acid, behenic acid, tricosanic acid or behenic acid.Described esterification is well known to those skilled in the art with the process of described dehydration
Technological means, the most particularly limit.Herein described feed additive also including, those skilled in the art are ripe
The additive known, such as diluent etc., has no particular limits this application.
Present invention also provides feed additive and have the application on the viral feedstuff of cyst membrane in preparation preventing and treating.Result of the test
Showing, the feed additive of the application can effectively prevent and treat the virus of cyst membrane.
The cyst membrane that the above-mentioned virus having cyst membrane is well known to those skilled in the art, concrete, described in have cyst membrane virus bag
Include:
A) Togaviridae
A) alphavirus: eastern equine encephalitis virus, western equine encephalitis virus, Nei Ruila equine encephalitis virus, Xin Debi
This virus, cover his virus；
B) rubella virus genus
C) Arterivirus: equine arteritis virus, pig reproduction and respiratory system syndrome virus, SHF virus,
Lactic acid dehydrogenase increases syndrome virus；
B) flaviviridae
A) Flavivirus: mobility encephalitis b virus, louping-ill virus, wesselsbron disease disease, Murray valley head
Scorching virus, turkey meningo-encephalitis virus；
B) pestivirus: Bovine Viral Diarrhea-Mucosal Disease Virus, swine fever virus, border disease virus；
C) class Hepacivirus
C) hat closes shape Viraceae
A) hat pass Tobamovirus: avian infectious bronchitis virus, transmissible gastro-enteritis virus, Porcine Epidemic Diarrhea
Brain malicious, porcine hemagglutinating is encephalitis virus, Mouse hepatitis virus, TCDV, canine coronavirus, other crown diseases
Poison；
B) grand Tobamovirus: berne virus, background of cloth da virus；
D) orthomyxoviridae family: equine influenza virus, swine influenza virus, poultry Influenza Virus；
E) Paramyxoviridae
A) paramyxovirus genus: Avian pneumo-encephalitis virus, type avian paramyxoviruses, parainfluenza virus subgroup；
B) Morbillivirus: canine distemper virus, rinderpest virus；
F) filamentous virus section: Marburg virus, Ebola virus；
G) Rhabdoviridae: rabies virus, bovine ephemeral fever virus, vesicular stomatitis virus, Fish strong shape virus；
H) Bunyaviridae
A) Bunyavirus, Ah card's pinta poison；
B) phlebotomus fever virus genus, Rift Valley fever virus；
C) Nairovirus, nairobi disease virus；
D) Hanta virases, epidemic haemorrhagic fever virus；
I) arenvirus section: lymphocytic choriomeningitis virus, Lassa virus, Junin virus, Ma Xiubo disease
Poison；
J) Retroviridae
A) " mammal " Type B retrovirus retrovirus belongs to: mouse mammary adenoma virus；
B) " mammal " c-type retrovirus retrovirus belongs to: mouse leukaemia virus and mouse sarcoma virus, feline leukaemia virus
With cat sarcoma virus, avian reticuloendotheliosis virus groups；
C) fowl c-type retrovirus retrovirus belongs to: fowl leukocyte hypertrophy disease virus, fowl myeloblast hypertrophy disease virus, fowl bone marrow are thin
Born of the same parents' tumor virus 29, rous sarcoma virus, RU2 sarcoma virus, Fujinami sarcoma virus, Y73 sarcoma virus, MH2 fowl cancer virus；
D) D type retrovirus retrovirus belongs to: monkey D type retrovirus retrovirus, sheep adenocarcinoma of lung virus；
E) bovine leucosis-people belongs to addicted to T cell retrovirus retrovirus: bovine leukemia virus；
F) lentivirus: primate Slow virus group, sheep/goat Slow virus group, horse Slow virus group, cat slow virus
Group, cattle Slow virus group；
G) Spumavirus；
K) Poxviridae
A) orthopoxvirus: vaccinia virus, smallpox virus and vaccinia virus, rabbitpox virus, mice infectiousness take off pedopathy disease
Poison, buffalo pox virus, camelpox virus, contagious pustular stomatitis virus, monkey pox virus；
B) Avipoxvirus: bird pox virus, pigeon avipoxvirus, turkey pox virus；
C) Capripoxvirus: sheep pox virus, goat capripoxvirus, lumpy skin disease virus；
D) rabbitpox virus belongs to: myxoma virus, rabbit fibroma virus, pernicious rabbit fibroma virus, other fibroma viruses；
D) Suipoxvirus；
E) parapoxvirus belong to: sheep contagiousness dermatitis impetiginosa virus, pseudocowpox virus, ulcerative stomatitis of cattle virus,
New Zealand's red deer parapoxvirus, other parapoxviruses；
F) Molluscipoxvirus；
G) tooth tower Poxvirus: tooth bar monkey tumor poxvirus, that poxvirus of tower；
L) herpetoviridae: pseudorabies virus, equine abortion virus, infectious bovine rhinotrachetis virus, cattle are exedens
Mammilitis virus (attached) A Leidun virus, malignant catarrhal fever virus, procine inclusion body rhinitis virus, canine alphaherpesvirus, cat nose trachea
Scorching virus, marek's disease virus, chicken infectivity throat trachea fire virus, duck plague virus；
M) Hepadnaviridae
A) Hepadnavirus: woodchuck hepatitis virus, ground squirrel hapatitis virus, tree squirrel hepatitis virus；
B) Avihepadnavirus: DHB, heron hepatitis B virus；
N) Iridoviridae: iridescent virus, Chloriridovirus genus, Ranavirus, Lymphocystivirus, " class Carassius auratus
Virus 1 type Tobamovirus "；
O) virus of the Bao Na disease in unfiled virus and African swine fever virus.
Present invention also provides a kind of feedstuff, it includes normal feedstuff and feed additive, wraps in described feed additive
Include in the ester of the high fatty alcohol described in such scheme and high fatty alcohol one or both.
Described feedstuff is had no particular limits by the application, and described feedstuff can be pig feed, cattle feedstuff, sheep feedstuff, chicken
Feedstuff, duck feed, goose feedstuff, fish meal, shrimp feed, Eriocheir sinensis feedstuff, dog feed, cat feed, ermine feedstuff, deer feedstuff, turtle feed, Trionyx sinensis Wiegmann
Feedstuff, shellfish feedstuff, Monopteri albi feedstuff, pigeon feed, quail feed, fodder for snake, horse feedstuff or donkey feedstuff.
The feedstuff that normal feedstuff in herein described feedstuff is well known to those skilled in the art, does not has spy to this application
Other restriction.The concentration of the feed additive in herein described feedstuff be preferably 1～25000mg/kg, more preferably 100～
20000mg/kg, in certain embodiments, more preferably 300～5000mg/kg.Feed additive in the application feedstuff is permissible
Including other additives, it is also possible to without other additives, this application is had no particular limits.
In order to be further appreciated by the present invention, the feed additive provided the present invention below in conjunction with embodiment is carried out specifically
Bright, protection scope of the present invention is not limited by the following examples.
Feedstuff in following example is feedstuff well known to those skilled in the art, for commercially available prod；Following example
In raw material be commercially available prod.
Embodiment 1
In the chicken house of certain 50,000 plumage chicken in certain bird flu epidemic-stricken area, it is found to have and thinks and be likely to bird flu virus disease
Disease, during beginning every day have tens, hundreds of chicken deaths, dead symptom is typical case's bird flu symptom, chicken more than 300
On the dead same day, chicken house is divided into two by road surface, a house, the left side 30,000 plumage, the right 20,000 plumage, the feedstuff on the left side with the addition of
500ppm tadenan, the chicken feed on the right does not deals with, and remaining cultivating condition is completely the same.42 days as a result out after, left
The hen house on limit survives and delivers 26963 for sale, the rate of animals delivered to the slaughter-house 89.8%, chicken group in addition to experiment in early days has zero amount and is similar to bird flu symptom,
At the end of not do not find to show the viral chicken of bird flu symptom；And often there is substantial amounts of chicken death on the right, only 3679 plumages are lucky
Good fortune survives, and survival rate only has 643 chickens at the end of only having 18.40%, and experiment have slight to mild or moderate bird flu symptom,
In view of the importance of thing, buried for these 3679 whole execution, and in burying hole, it is filled with substantial amounts of Calx (hydroxide
Calcium), the right hen house rate of animals delivered to the slaughter-house is zero.
Embodiment 2
There is not bird flu laying hen field in certain 100,000 plumage in bird flu epidemic-stricken area, is divided into two by hen house, wherein 50,000
Adding 120ppm tadenan in the feedstuff of plumage chicken, another side 50,000 plumage chicken all inoculates avian influenza vaccine, remaining cultivating condition
Completely the same.Through an egg-laying peak, the laying rate of the chicken that feedstuff adds tadenan is 97.53%, does not find
The chicken that the symptom of bird flu is dead；And vaccinated chicken group, laying rate only has 81.25%, and successively has 39 the most doubtful
The chicken that bird flu symptom is dead, illustrates that the laying rate of laying hen is had little to no effect by tadenan, has also carried out good to chicken group
Good protection, is better than the chicken group of avian influenza vaccine inoculation.
Embodiment 3
In certain large-scale plant in pig blue-ear disease epidemic-stricken area, 2589 replacement gilts therein, it is divided into respectively 2000
Head and two groups of 859, to 2000 replacement gilt forage therein are added the tadenan of 260ppm always, output
Suckling piglet daily ration also add 80ppm tadenan, and in the porkling feedstuff of the replacement gilt of 859 and output all without
Tadenan, remaining cultivating condition is completely the same.Through observation and the record of 730 days, feedstuff adds tadenan
Replacement gilt group's retention rate 98.75%, farrowing next year single head sow year deliver pig 24 for sale, and do not take in and be added with docosane
859 swinerys of alcohol feedstuff, eliminate 289, and retention rate 66.36% has 137 sows that die of illness, has typical pig blue-ear disease corpse
Inspection feature, the swinery single head sow of reservation, next year delivers pig for sale 14, far below the swinery adding tadenan.Pig is blue
Otopathy poison is to affect pig reproduction and respiratory system is the most viral, belongs to the arteritis virus in togavirus kind, and it is a kind of allusion quotation
The virus having cyst membrane of type.Therefore, tadenan has good prevention and prevention effect to pig blue-ear disease poison.
Embodiment 4
Porcine pseudorabies has been broken out on certain fattening pig farm, after all delivering for sale, has carried out identifying oneself to sterilize thoroughly, due to pig valency
The highest, profit of raising pigs is the highest, pig farm the most vacant certain time, the most large quantities of enter pig 2500, attempt 2000 therein
Adding swine rations 150ppm, big swine rations 200ppm in tadenan in 30kg pig feed, result survives 1996, and all
Delivering for sale, in addition to the four-head pig of Early death, do not find obvious pseudorabies symptom in 1996 pigs, the full phase expects meat 2.87:1,
Belong to normal feed conversion level；And feedstuff does not add 500 pigs of tadenan, survive 395, actual delivered for sale
364, having 31 cad pigs, and marketing time extends 43 days, the rate of animals delivered to the slaughter-house 72.8%, feedstuff feedstuff-meat ratio is 3.43:1, feedstuff
Conversion ratio is far below normal level, and the most dead 105 of production period, mortality rate 21%, wherein 22 postmortems have obvious puppet
Rabies anatomical features, 86 dead pigs have obvious pseudorabies disease before dying of illness, even if the pig survived one's illness, the speed of growth
Also far below 2000 the pig swinery performances adding tadenan in feedstuff.
Embodiment 5
In the chicken house of certain 50,000 plumage chicken in certain bird flu epidemic-stricken area, it is found to have and thinks and be likely to bird flu virus disease
Disease, during beginning every day have tens, hundreds of chicken deaths, dead symptom is typical case's bird flu symptom, chicken more than 300
On the dead same day, chicken house is divided into two by road surface, a house, the left side 30,000 plumage, the right 20,000 plumage, the feedstuff on the left side with the addition of
1000ppm lauryl alcohol, the chicken feed on the right does not deals with, and remaining cultivating condition is completely the same.42 days as a result out after, the left side
Hen house survives and delivers 19365 for sale, the rate of animals delivered to the slaughter-house 64.55%, and chicken group, in addition to experiment has zero amount in early days and is similar to bird flu symptom, terminates
Time do not find to show the viral chicken of bird flu symptom；And often there is substantial amounts of chicken death on the right, only 6743 plumages become by sheer good luck
Living, survival rate only has 1764 chickens at the end of only having 33.71%, and experiment have slight to mild or moderate bird flu symptom, examines
Consider the importance to thing, buried for these 6743 whole execution, and in burying hole, be filled with substantial amounts of Calx (calcium hydroxide),
The right hen house rate of animals delivered to the slaughter-house is zero.Thus explanation lauryl alcohol has certain preventive effect to bird flu.
Embodiment 6
There is not bird flu laying hen field in certain 100,000 plumage in bird flu epidemic-stricken area, is divided into two by hen house, wherein 50,000
Adding 350ppm octacosanol in the feedstuff of plumage chicken, another side 50,000 plumage chicken all inoculates avian influenza vaccine, remaining cultivating condition
Completely the same.Through an egg-laying peak, the laying rate of the chicken that feedstuff adds octacosanol is 91.41%, does not find
The chicken that the symptom of bird flu is dead；And vaccinated chicken group, laying rate only has 82.35%, and successively has 65 the most doubtful
The chicken that bird flu symptom is dead, illustrates that octacosanol has good protective effect to the laying hen of the laying hen field of avian influenza infection,
It is better than the chicken group of avian influenza vaccine inoculation.
Embodiment 7
Porcine pseudorabies has been broken out on certain fattening pig farm, after all delivering for sale, has carried out identifying oneself to sterilize thoroughly, due to pig valency
The highest, profit of raising pigs is the highest, pig farm the most vacant certain time, the most large quantities of enter pig 10000, attempt 9500 therein
Adding swine rations 350ppm, big swine rations 550ppm in tadenan butyl ester in 30kg pig feed, result survives 9454, and
All deliver for sale, in addition to 46 pigs of Early death, 9464 pigs do not find obvious pseudorabies symptom, the rate of animals delivered to the slaughter-house
99.62%, material meat 2.76:1 of full phase, belong to normal feed conversion level；And feedstuff does not add tadenan methyl ester
500 pigs, have survived 297, actual deliver 187 for sale, have 110 cad pigs, and marketing time extends 67 days, the rate of animals delivered to the slaughter-house
37.4%, feedstuff feedstuff-meat ratio is 3.95:1, and feed conversion rate is far below normal level, the most dead 203 of production period, death
Rate 40.6%, wherein 175 postmortems have obvious pseudorabies anatomical features, 196 dead pigs to have obvious puppet before dying of illness
Rabies disease, even if the pig survived one's illness, the speed of growth is also far below 9500 pigs adding tadenan methyl ester in feedstuff
The performance of swinery.
Same method, it is possible to obtain tridecanol, myristyl alcohol, pentadecanol, hexadecanol, Heptadecyl alcohol, stearyl alcohol, nonadecanol,
Eicosanol, two undecyl alcohols, tricosanol, tetracosanol, pentacosyl alcohol, hexacosyl alcohol, heptacosanol, nonacosanol, melissyl alcohol
And ester adds preventing to have the virus of cyst membrane to have certain effect in feedstuff.
The explanation of above example is only intended to help to understand method and the core concept thereof of the present invention.It is right to it should be pointed out that,
For those skilled in the art, under the premise without departing from the principles of the invention, it is also possible to the present invention is carried out
Some improvement and modification, these improve and modify in the protection domain also falling into the claims in the present invention.
Described above to the disclosed embodiments, makes professional and technical personnel in the field be capable of or uses the present invention.
Multiple amendment to these embodiments will be apparent from for those skilled in the art, as defined herein
General Principle can realize without departing from the spirit or scope of the present invention in other embodiments.Therefore, the present invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and principles disclosed herein and features of novelty phase one
The widest scope caused.
Claims (9)
1. a feed additive, including one or both in the ester of high fatty alcohol and high fatty alcohol.
Feed additive the most according to claim 1, it is characterised in that described high fatty alcohol include lauryl alcohol, 13
Alcohol, myristyl alcohol, pentadecanol, hexadecanol, Heptadecyl alcohol, stearyl alcohol, nonadecanol, eicosanol, two undecyl alcohols, tadenan, two
One in tridecanol, tetracosanol, pentacosyl alcohol, hexacosyl alcohol, heptacosanol, octacosanol, nonacosanol and melissyl alcohol
Or it is multiple.
Feed additive the most according to claim 1, it is characterised in that the ester of described high fatty alcohol is by described senior fat
It is dehydrated after fat alcohol and fatty acid esterification and obtains.
Feed additive the most according to claim 3, it is characterised in that described fatty acid selected from formic acid, acetic acid, propanoic acid,
Butanoic acid, valeric acid, caproic acid, enanthic acid, octanoic acid, n-nonanoic acid, capric acid, undecanoic acid, lauric acid, tridecanoic acid, myristic acid, pentadecanoic acid, palmitin
Acid, heptadecanoic acid, stearic acid, nonadecanoic acid, 20 acid, heneicosoic acid, behenic acid, tricosanic acid or behenic acid.
5. the feed additive described in any one of Claims 1 to 4 has the application on the viral feedstuff of cyst membrane in preparation preventing and treating.
Application the most according to claim 5, it is characterised in that described in have the virus of cyst membrane to include:
A) alphavirus in Togaviridae, rubella virus genus, Arterivirus,
B) Flavivirus in flaviviridae, pestivirus, class Hepacivirus,
C) hat during hat closes shape Viraceae closes Tobamovirus, grand Tobamovirus,
D) equine influenza virus in orthomyxoviridae family, swine influenza virus, poultry Influenza Virus,
E) paramyxovirus genus in Paramyxoviridae, Morbillivirus,
F) Marburg virus in filamentous virus section, Ebola virus,
G) rabies virus in Rhabdoviridae, bovine ephemeral fever virus, vesicular stomatitis virus, Fish strong shape virus,
H) Bunyavirus in Bunyaviridae, phlebotomus fever virus genus, Nairovirus, Hanta virases,
I) lymphocytic choriomeningitis virus in arenvirus section, Lassa virus, Junin virus, Ma Xiubo disease
Poison,
J) the mammalian B retrovirus retrovirus in Retroviridae belongs to, mammal c-type retrovirus retrovirus belongs to, fowl c-type is anti-
Retroviral genus, D type retrovirus retrovirus genus, bovine leucosis-people are addicted to T cell retrovirus retrovirus genus, lentivirus, foamy virus
Belong to,
K) orthopoxvirus in Poxviridae, Avipoxvirus, Capripoxvirus, rabbitpox virus genus, Suipoxvirus, secondary pox
Tobamovirus, Molluscipoxvirus, tooth tower Poxvirus,
L) pseudorabies virus in herpetoviridae, equine abortion virus, infectious bovine rhinotrachetis virus, the exedens breast of cattle
Head scorching virus (attached) A Leidun virus, malignant catarrhal fever virus, procine inclusion body rhinitis virus, canine alphaherpesvirus, Feline Rhinotracheitis
Virus, marek's disease virus, chicken infectivity throat trachea fire virus, duck plague virus,
M) Hepadnavirus in Hepadnaviridae, Avihepadnavirus,
N) iridescent virus in Iridoviridae, Chloriridovirus genus, Ranavirus, Lymphocystivirus, eka-gold fish diseases
Poison 1 type Tobamovirus,
Or O) Bao Na disease virus in unfiled virus and African swine fever virus.
7. a feedstuff, including normal feedstuff and feed additive, it is characterised in that described feed additive includes that right is wanted
Ask in the ester of the high fatty alcohol described in 1～4 any one and high fatty alcohol one or both.
Feedstuff the most according to claim 7, it is characterised in that in the ester of described high fatty alcohol and high fatty alcohol
Plant or two kinds of concentration in described feedstuff are 1～25000mg/kg.
Feedstuff the most according to claim 7, it is characterised in that described feedstuff includes pig feed, cattle feedstuff, sheep feedstuff, chicken
Feedstuff, duck feed, goose feedstuff, fish meal, shrimp feed, Eriocheir sinensis feedstuff, dog feed, cat feed, ermine feedstuff, deer feedstuff, turtle feed, Trionyx sinensis Wiegmann
Feedstuff, shellfish feedstuff, Monopteri albi feedstuff, pigeon feed, quail feed, fodder for snake, horse feedstuff or donkey feedstuff.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106804939A (en) * | 2017-01-26 | 2017-06-09 | 江西省科学院生物资源研究所 | A kind of additive for feed for piglets of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN106858136A (en) * | 2017-01-26 | 2017-06-20 | 江西省科学院生物资源研究所 | A kind of poultry feed addictive of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN106858182A (en) * | 2017-01-26 | 2017-06-20 | 江西省科学院生物资源研究所 | A kind of feeding additive aquatic animal of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN107223790A (en) * | 2017-01-26 | 2017-10-03 | 江西省科学院生物资源研究所 | It is a kind of to produce feed conditioning agent of low-cholesterol egg and preparation method thereof and the formula forage containing the conditioning agent |
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| CN102696883A (en) * | 2012-05-23 | 2012-10-03 | 浙江大学 | Feed additive and application of feed additive |
| CN103392929A (en) * | 2013-07-19 | 2013-11-20 | 清远海贝生物技术有限公司 | Premixing agent for controlling water content of finished fish and shrimp pellet feed product and using method of premixing agent |
| CN105767531A (en) * | 2016-03-21 | 2016-07-20 | 湖南晶天科技实业有限公司 | Feed additive and feed |
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| CN102696883A (en) * | 2012-05-23 | 2012-10-03 | 浙江大学 | Feed additive and application of feed additive |
| CN103392929A (en) * | 2013-07-19 | 2013-11-20 | 清远海贝生物技术有限公司 | Premixing agent for controlling water content of finished fish and shrimp pellet feed product and using method of premixing agent |
| CN105767531A (en) * | 2016-03-21 | 2016-07-20 | 湖南晶天科技实业有限公司 | Feed additive and feed |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106804939A (en) * | 2017-01-26 | 2017-06-09 | 江西省科学院生物资源研究所 | A kind of additive for feed for piglets of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN106858136A (en) * | 2017-01-26 | 2017-06-20 | 江西省科学院生物资源研究所 | A kind of poultry feed addictive of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN106858182A (en) * | 2017-01-26 | 2017-06-20 | 江西省科学院生物资源研究所 | A kind of feeding additive aquatic animal of the rice bran extract of collection of illustrative plates containing particular fingerprint and preparation method thereof and the formula forage containing the additive |
| CN107223790A (en) * | 2017-01-26 | 2017-10-03 | 江西省科学院生物资源研究所 | It is a kind of to produce feed conditioning agent of low-cholesterol egg and preparation method thereof and the formula forage containing the conditioning agent |
| CN107223790B (en) * | 2017-01-26 | 2020-05-26 | 江西省科学院生物资源研究所 | Feed regulator for producing low-cholesterol eggs, preparation method thereof and formula feed containing regulator |
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