CN106226897A - A kind of tissue slice scanning means based on ordinary optical microscope and smart mobile phone - Google Patents
A kind of tissue slice scanning means based on ordinary optical microscope and smart mobile phone Download PDFInfo
- Publication number
- CN106226897A CN106226897A CN201610746297.5A CN201610746297A CN106226897A CN 106226897 A CN106226897 A CN 106226897A CN 201610746297 A CN201610746297 A CN 201610746297A CN 106226897 A CN106226897 A CN 106226897A
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- mobile phone
- smart mobile
- microscope
- tissue slice
- ordinary optical
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/362—Mechanical details, e.g. mountings for the camera or image sensor, housings
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04M—TELEPHONIC COMMUNICATION
- H04M1/00—Substation equipment, e.g. for use by subscribers
- H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
- H04M1/724—User interfaces specially adapted for cordless or mobile telephones
- H04M1/72403—User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
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- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Multimedia (AREA)
- Human Computer Interaction (AREA)
- Computer Networks & Wireless Communication (AREA)
- Signal Processing (AREA)
- Microscoopes, Condenser (AREA)
Abstract
In order to provide, a kind of picture quality is high, convenient to be used and digital tissue slice scanning means with low cost, the present invention discloses a kind of based on smart mobile phone with the digital tissue slice scanning means of ordinary optical microscope, it is characterised in that: it is made up of fixed frame for microscope, ordinary optical microscope, smart mobile phone, focusing and slide displacing mechanism, smart mobile phone fixed mount and computer.By smart mobile phone, computer and microscopical Function Integration Mechanism to together with, with low cost and easily mode realize the digitized of tissue slice.
Description
Technical field
The invention belongs to mechanical manufacturing field, particularly relate to a kind of based on ordinary optical microscope with the tissue of smart mobile phone
Section scanning means.
Background technology
Tissue slice is the capsule information of medical diagnosis on disease, scientific research and teaching, by numeral tissue slice scanner by tradition
Tissue slice be scanned, be converted into numeral tissue slice, it is simple to preserve and transmit, therefore, numeral tissue slice scanner
It is increasingly becoming one of necessary equipment of hospital and other scientific research institutions.But, existing numeral tissue slice scanner is more high
Expensive (about 500,000 yuans every), use frequency low and cause use cost high, and basic hospital needs but is not easily accepted by, resistance
Hinder the progress of relevant Clinics, scientific research and teaching.Therefore, it is necessary to a kind of picture quality of exploitation is high, use cost is low and
It is easy to the digital tissue slice scanning means promoted.It is the indispensability of hospital in view of ordinary optical microscope (hereinafter referred to as microscope)
Equipment, and smart mobile phone (hereinafter referred to as mobile phone) is universal in medical personnel, so, mobile phone and microscope are integrated
Become tissue slice scanning means and can reduce cost, promote the popularization and application of numeral tissue slice scanning technique.
Summary of the invention
It is an object of the invention to: for the problem that existing tissue slice scanner use cost is high, it is provided that a kind of image
Quality is high, convenient to be used and digital tissue slice scanning means with low cost.
For solving above-mentioned technical problem, the present invention provides a kind of tissue based on ordinary optical microscope and smart mobile phone to cut
Sheet scanning means, it is characterised in that: fixed by fixed frame for microscope, microscope, mobile phone, focusing and slide displacing mechanism, mobile phone
Frame and computer composition.
Described fixed frame for microscope is to be made up of 1 framework and 4 ~ 8 knobs, and described framework is 1 and is become by 4 skirt
Frame structure, size is preferable over and can just microscope stand be enclosed within frame structure, 4 limits of described frame structure have 4 ~
8 knobs inwardly stretched out, the medial extremity of each described knob is with knob cushion block.Described microscopical microscope base is positioned over aobvious
Micro mirror fixed mount central authorities, inwardly twist knob, fixed frame for microscope can be firmly fixed with microscope together with.
Described focusing and slide displacing mechanism are made up of three motor modules and a CPU.Each described electricity
Machine module is by each composition of motor mounting rack, motor, worm gear and worm screw.Described CPU, including processing chip
With driving module, it is used for driving and controlling the operation of three motors.Described motor mounting rack is fixed on described fixed frame for microscope
Reserved location, be used for fixing motor.Worm gear is respectively fitted over microscope carefully accurate burnt spiral, transverse shifting handwheel and vertically moves
On handwheel, described worm screw the power of motor is transferred to microscope carefully accurate burnt spiral, transverse shifting handwheel and longitudinal direction respectively and moves
Start wheel, thus complete the tissue slice on the fine setting of microscope focus and microscope carrier in left and right and former and later two directions
On movement.
Described mobile phone fixing frame is made up of mobile phone fixed support and two knobs, is used for fixing mobile phone, makes described mobile phone
Photographic head is stable in the position of aligming microscope eyepiece, it is simple to gather the image from microscope ocular.
Described mobile phone possesses image acquisition and by the function of the Internet transmission image, and the resolution of described image reaches 500
More than ten thousand pixels；Described computer is connected with CPU, and described computer is connected with the Internet, and described computer passes through software system
System controls three described motor modules, and described computer receives, by the Internet, the image that mobile phone gathers, according to the definition of image
Microscopical focal length is adjusted, according to image acquisition need the tissue slice on microscope carrier is carried out left and right and
Position adjustments on former and later two directions.
It is an advantage of the current invention that: make full use of the equipment popularized in medical institutions and medical worker (mobile phone, aobvious
Micro mirror and computer), add a small amount of easy device and software on this basis, thus with high-quality and easily mode realize tissue
The scanning of section, use cost is reduced to about 1/10th of existing numeral tissue slice scanner.
Accompanying drawing explanation
Fig. 1 is axis side view of the present invention；
Fig. 2 is motor module installation site zoomed-in view of the present invention；
Fig. 3 is motor module one axis side view of the present invention；
Fig. 4 is motor module two axis side view of the present invention；
Fig. 5 is motor module three axis side view of the present invention；
Fig. 6 is mobile phone installing rack axis side view of the present invention.
Illustrate: 1, microscope；2, M5 knob；3, mobile phone fixing frame；4, computer；5, worm gear；6, worm screw；7、12、13、
Motor mounting rack；8, motor；9, connecting line；10, M10 knob；11, knob cushion block；14, fixed frame for microscope；17,18,19, electricity
Machine module；Mobile phone 20.
Detailed description of the invention
Below in conjunction with the accompanying drawings, the invention will be further described.
A kind of tissue slice scanning means based on ordinary optical microscope and smart mobile phone disclosed by the invention, by micro-
Mirror fixed mount 14, microscope 1, mobile phone 20, focusing and slide displacing mechanism, mobile phone fixing frame 3 and computer 4 form.
Fixed frame for microscope 14 is made up of 1 framework and 8 M10 knobs 10, and 4 limits of framework have 8 inwardly to stretch out
M10 knob 10, the medial extremity of each M10 knob 10 is with 1 knob cushion block 11, when being positioned over micro-by microscopical microscope base
During mirror fixed mount 14 central authorities, inwardly twist 8 M10 knobs 10, fixed frame for microscope 14 and microscope 1 can be firmly fixed to one
Rise.
Focusing and slide displacing mechanism are made up of 17,18,19 and 1 CPU of 3 motor modules.Each motor
Module is by motor mounting rack 7,12,13, motor 8, worm gear 5 and each composition of worm screw 6.CPU includes processing core
Sheet and driving module, can drive and control the operation of three motors 8.Motor mounting rack 7,12,13 is fixed on fixed frame for microscope
The reserved location of 14,3 motors 8 are separately fixed on motor mounting rack 7,12,13.It is thin that three worm gears 5 are respectively fitted over microscope
Accurate burnt spiral, transverse shifting handwheel and vertically move on handwheel, be transferred to motor power worm gear 5 by worm screw 6, thus complete to show
The motion on left and right and former and later two directions of the tissue slice in the fine setting of micro mirror focal length and microscope carrier.
Mobile phone fixing frame 3 is made up of mobile phone fixed support and two M5 knobs 2, makes the photographic head of described mobile phone 20 stablize
The position of aligming microscope eyepiece.
In use, connect computer 4 and CPU by connecting line 9, and provided to motor 8 by connecting line 9
Power supply, is also turned on the Internet by computer 4 and mobile phone 20, is positioned on microscope carrier by tissue slice, according to intending collection
The amplification of image requires to select microscope objective, and regulation microscope is to seeing tissue slice by microscope ocular
Target area.Mobile phone 20 is fixed to the position of the stable aligming microscope eyepiece of photographic head, by micro-by mobile phone fixing frame 3
Mirror fixed mount 14 is fixed on microscopical microscope base, installs focusing and slide displacing mechanism.Start the image acquisition merit of mobile phone 20
Can, adjust to the picture rich in detail that can get tissue slice at mobile phone 20.The tissue slice images gathered is passed through mutually by mobile phone 20
Networking transport is to computer 4, and computer 4 processes image, and adjusts microscope focus in real time, according to Transformation Graphs according to the definition of image
As the position needing regulation tissue slice of pickup area, thus collect the picture rich in detail of whole tissue slice.
Claims (4)
1. one kind based on smart mobile phone and the digital tissue slice scanning means of ordinary optical microscope, it is characterised in that: by showing
Micro mirror fixed mount, ordinary optical microscope, smart mobile phone, focusing and slide displacing mechanism, smart mobile phone fixed mount and computer group
Become.
A kind of digital tissue slice based on smart mobile phone and ordinary optical microscope the most according to claim 1 scanning dress
Put, it is characterised in that:
Described focusing and slide displacing mechanism are made up of three motor modules and a CPU, each described motor mould
Block is by each composition of motor mounting rack, motor, worm gear and worm screw；
Described CPU, including processing chip and driving module, for driving and control the operation of three motors；
Described motor mounting rack is fixed on the reserved location of described fixed frame for microscope；
Three motor modules connect microscope carefully accurate burnt spiral, transverse shifting handwheel respectively and vertically move handwheel, are used for realizing
The motion on left and right and former and later two directions of the tissue slice in the fine setting of microscope focus and microscope carrier.
A kind of digital tissue slice based on smart mobile phone and ordinary optical microscope the most according to claim 1 scanning dress
Put, it is characterised in that: described smart mobile phone fixed mount is made up of mobile phone fixed support and two knobs, is used for fixing smart mobile phone
Photographic head stable in the position of aligming microscope eyepiece.
A kind of digital tissue slice based on smart mobile phone and ordinary optical microscope the most according to claim 1 scanning dress
Put, it is characterised in that: described computer is connected with CPU, and described computer is connected with the Internet, by software system control
Making three described motor modules, described computer receives, by the Internet, the image that smart mobile phone gathers, according to the definition of image
Microscopical focal length is adjusted, according to image acquisition need the tissue slice on microscope carrier is carried out left and right and
Position adjustments on former and later two directions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610746297.5A CN106226897B (en) | 2016-08-29 | 2016-08-29 | A kind of histotomy scanning means based on ordinary optical microscope and smart phone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610746297.5A CN106226897B (en) | 2016-08-29 | 2016-08-29 | A kind of histotomy scanning means based on ordinary optical microscope and smart phone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106226897A true CN106226897A (en) | 2016-12-14 |
| CN106226897B CN106226897B (en) | 2019-07-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610746297.5A Active CN106226897B (en) | 2016-08-29 | 2016-08-29 | A kind of histotomy scanning means based on ordinary optical microscope and smart phone |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106707493A (en) * | 2017-03-06 | 2017-05-24 | 四川农业大学 | Microscope shooting assisting device |
| CN106990522A (en) * | 2017-06-05 | 2017-07-28 | 郑州大学第附属医院 | The electric adjusting apparatus of micro- mirror scanning type article carrying platform |
| CN109031641A (en) * | 2018-08-21 | 2018-12-18 | 北京青燕祥云科技有限公司 | A kind of digitalized sliced sheet system and pathological section analysis method |
| CN109147912A (en) * | 2018-08-30 | 2019-01-04 | 宁波江丰生物信息技术有限公司 | A kind of digital slices scan method and device |
| WO2021093109A1 (en) * | 2019-11-14 | 2021-05-20 | 武汉兰丁智能医学股份有限公司 | Mobile phone-based miniature microscopic image acquisition device, image splicing method, and image recognition method |
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| US11586028B2 (en) * | 2019-11-14 | 2023-02-21 | Wuhan Landing Intelligence Medical Co., Ltd. | Mobile phone-based miniature microscopic image acquisition device and image stitching and recognition methods |
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Effective date of registration: 20230301 Address after: 550081 area B, Jinhua garden south, Guanshan North Road, Jinhua Garden Street, guanshanhu District, Guiyang City, Guizhou Province Patentee after: Guiyang demandoo Medical Technology Co.,Ltd. Address before: 330001 Room 202, Unit 1, Residential Building, No. 39, Vanke Runyuan, Qingyunpu District, Nanchang City, Jiangxi Province Patentee before: NANCHANG DEMANDUO TECHNOLOGY Co.,Ltd. |
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