CN106220867A - A kind of elecrtonegativity chitin nanofiber hydrogels and the preparation method of aeroge - Google Patents
A kind of elecrtonegativity chitin nanofiber hydrogels and the preparation method of aeroge Download PDFInfo
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- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
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- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
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- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
- C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
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Abstract
The invention discloses the preparation method of a kind of elecrtonegativity chitin nanofiber hydrogels, including: 1) take chitin raw material and carry out pretreatment, it is thus achieved that chitin slurry；2) the chitin slurry that step 1) obtains is through 2, and 2,6,6 tetramethyl piperidine nitrogen oxides catalyst oxidation systems process, it is thus achieved that TEMPO aoxidizes elecrtonegativity chitin；3) step 2) the elecrtonegativity chitin that obtains prepares elecrtonegativity chitin nanofiber dispersion liquid through mechanical treatment in weak alkaline aqueous solution or water；4) the elecrtonegativity chitin nanofiber dispersion liquid that step 3) obtains processes the elecrtonegativity chitin nanofiber hydrogels preparing physical crosslinking through acid coagulating bath or acid vapors bath.The elecrtonegativity chitin nanofiber hydrogels of the present invention, the preparation method of aeroge, method is simple and workable, can prepare the hydrogel that realize of low cost；Prepared chitin nanofiber hydrogels, that aerogel material has form is good, and concentration is low, the advantage that intensity is high.
Description
Technical field
The present invention relates to chitinous applied technical field, be specifically related to a kind of elecrtonegativity chitin nanofiber hydrogels
And the preparation method of aeroge.
Background technology
Chitin is the aminopolysaccharide biopolymer that a class formation is similar to cellulose.1963, Rudall was according to X-
The result that Ray Diffraction Spectroscopy obtains, it is proposed that chitin also exists tri-kinds of crystal formations of α, β, γ.These three crystal formation is by intramolecular
Formed with intermolecular different hydrogen bond action.Wherein, α-chitin is mostly present in the shell of crustaceans, as
Crusta Penaeus seu Panulirus, Carapax Eriocheir sinensis etc.；β-chitin is then primarily present in the biologies such as squid parietal bone, pipe worm, diatom.At industry processes
In, chitin mainly passes through acid treatment and calcium carbonate is sloughed in alkali process and protein obtains.Chitin has the most widely should
By value, such as: the field such as skin care item, organizational project, biomedical dressing, dentistry, engineering of water treatment, pharmaceutical carrier.In conjunction with it
Special biogenetic derivation, high-crystallinity, physical strength, good bio-compatibility and the character of nanofiber can be separated into,
Chitin has been developed as new high functional material of great interest.
Patent in terms of chitin nanofiber based aquagel, aeroge is less at present.Patent CN103357059A is open
A kind of chitin gel adhesive bandage and preparation method thereof, the method mainly uses chitin, sodium polyacrylate, carboxymethyl cellulose
Element sodium, polyvidone, gelatin, dihydroxyaluminum aminoacetate, glycerol, purified water and acetic acid are mixed in proportion, and prepare and have anti-inflammation and sterilization, acceleration wound
The adhesive bandage material of mouth healing.Patent CN102942660B discloses the nano combined three dimensional gel of a kind of natural biological crosslinking and props up
Frame and preparation method thereof, the method mainly use acrylamide monomers, inorganic nano clay, containing amino, carboxyl or hydroxyl
The biopolymer (including chitin) of base functional group and Biological cross-linker genipin are mixed in proportion to prepare and can be used for curing
The biologic bracket material cultivated with transplanting, drug release and cell.In terms of existing article works, Chuchu Chen et al. profit
In calcium chloride/methanol system, chitin nanofiber hydrogels and aerogel material is prepared, knot by the method for vacuum filtration
Fruit finds that chitin nanofiber gel shows good mechanical performance under hygrometric state condition.Changyu Chang et al. profit
Dissolving chitin by alkali urea system, and prepare the chitin chemical water gel rubber material of epichlorohydrin cross-linked further, experiment is sent out
Existing chitin hydrogel not only has mechanical strength is high, hole is homogeneous feature and 293T cell is had good bio-compatible
Property and nontoxic property, have a good application prospect in terms of biological support.
Although but chitin gel material raw material disclosed in above patent containing chitin is not prepared pure bearing
Electrical chitin nanofiber gel material, and in existing article the preparation process of chitin nanofiber hydrogels complicated,
Power consumption is big and does not has the physical gel preparation report under the conditions of super low concentration (< 0.6%).
Summary of the invention
Goal of the invention: for the exploration of chitin nanofiber application aspect, it is an object of the present invention to provide a kind of elecrtonegativity
The preparation method of chitin nanofiber hydrogels.The elecrtonegativity chitin mainly solving how to make super low concentration (< 0.6%) is received
A rice fiber dispersion gelation difficult problem, is not required to, by complex processes such as chemical crosslinkings, do not adding any other macromolecular compound
In the case of prepare the physical hydrogel that mechanical strength is higher.It is a further object of the present invention to provide a kind of elecrtonegativity chitin
The preparation method of nanofiber aeroge.
Technical scheme: for achieving the above object, the technical solution used in the present invention is:
The preparation method of a kind of elecrtonegativity chitin nanofiber hydrogels, comprises the following steps:
1) take chitin raw material and carry out pretreatment, it is thus achieved that chitin slurry；
2) the chitin slurry that step 1) obtains is through 2,2,6,6-tetramethyl piperidine-nitrogen-oxide (TEMPO) catalyst oxidation system
(TEMPO/NaBr/NaClO) process, it is thus achieved that TEMPO aoxidizes elecrtonegativity chitin；
3) step 2) the elecrtonegativity chitin that obtains prepares elecrtonegativity chitin through mechanical treatment in the solution of pH 5-10
Nanofiber dispersion liquid；
4) the elecrtonegativity chitin nanofiber dispersion liquid that step 3) obtains processes preparation through acid coagulating bath or acid vapors bath
Obtain the elecrtonegativity chitin nanofiber hydrogels of physical crosslinking.
In step 1), described chitin raw material includes Crusta Penaeus seu Panulirus, Carapax Eriocheir sinensis.
Step 2) in, 2,2,6,6-tetramethyl piperidines-nitrogen-oxide catalyst oxidation system is: relative to chitin dry weight,
TEMPO addition is 0.05-0.5 mmol/g, and NaBr addition is 0.5-5 mmol/g, and NaClO addition is 2-8 mmol/
G chitin, pH is 10.
In step 3), described solution is weak alkaline aqueous solution or water.
In step 4), acid coagulating bath includes acetic acid coagulating bath, hydrochloric acid coagulating bath etc..
In step 4), acid vapors bath includes acetic acid steam bath, hydrochloric acid vapour bath etc..
In step 4), acid coagulating bath and steam bath process time are 6-120h.
The preparation method of a kind of elecrtonegativity chitin nanofiber aeroge, by the elecrtonegativity chitin nanometer prepared
Obtain after the dehydration of fiber water gel drying.
Described drying means is lyophilization, supercritical drying etc..
Beneficial effect: compared with prior art, present invention have the advantage that
1) the elecrtonegativity chitin nanofiber hydrogels of the present invention, the preparation method of aeroge, method is simple and operability
By force, can prepare the hydrogel that realize of low cost；
2) it is good that the chitin nanofiber hydrogels prepared by, aerogel material have form, and concentration is low, the advantage that intensity is high.
3) the method does not use any toxic chemical, the chitin nanofiber hydrogels prepared, aeroge material
Material not only has negative electricity characteristic but also has bio-compatible and nontoxic advantage, has good answering in terms of biological medicine
Use prospect.Can efficiently utilize biomass resource, widen the purposes of biomass, improve its use value, for efficiently utilizing biomass
Resource provides new thinking and approach.
4) present invention utilizes simplicity to be easy to get and steam coagulation with low cost bath, and gel preparation course is simply efficient, and energy
Successfully preparing the physical gel material that network structure is abundant under low consistency conditions, the application for chitin nanofiber provides
New methods in working.
5) use novel steam coagulation bath to prepare chitin nanofiber gel material, simple to operate efficiently, and preparation
The chitin nanofiber hydrogels material network structure-rich, the intensity that go out are high, and the negative electricity characteristic of hydrogel improves gel
Reactivity and biological activity.
Accompanying drawing explanation
Fig. 1 is elecrtonegativity chitin nanofiber testing result figure；Wherein, left figure is that TEMPO aoxidizes elecrtonegativity chitin
Nanofiber dispersion liquid digital photograph, right figure is elecrtonegativity chitin nanofiber transmission electron microscope picture；
Fig. 2 is elecrtonegativity chitin nanofiber hydrogels number figure；
Fig. 3 elecrtonegativity chitin nanofiber aeroge testing result figure；Wherein, left figure is elecrtonegativity chitin nanofiber gas
Gel digital photograph, right figure is elecrtonegativity chitin nanofiber aeroge scanning electron microscope (SEM) photograph.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further elaborated.Embodiment is to send out for illustrative not limiting
Bright.Any those of ordinary skill in this area, it will be appreciated that these embodiments limit the present invention never in any form, can do suitably
Amendment and without prejudice to the present invention essence and deviation the scope of the present invention.
The preparation of embodiment 1 chitin slurry
Take Carapax Eriocheir sinensis raw material, clean and cut into pieces, by the raw material after chopping through 1 M sodium hydroxide and 1 M hydrochloric acid alternate treatment
12h, processes three circulations and removes albumen in Carapax Eriocheir sinensis and calcareous, then with 0.5% NaClO2Solution bleaching delignification is except the color in Carapax Eriocheir sinensis
Element.After having bleached, with distilled water, bleaching Carapax Eriocheir sinensis is washed till neutrality, is placed in 4 DEG C of refrigerators preservation.Eriocheir sinensis will be bleached with pulverizer
Shell fragment is ground into pulpous state, obtains chitin slurry after purification.
Embodiment 2 TEMPO oxidation chitin and the preparation of elecrtonegativity chitin nanofiber dispersion liquid
The purification chitin weighing 0.016g TEMPO, 0.1g NaBr, 1g dry weight is separately added into stirring and dissolving in 200mL beaker.
The backward system that is uniformly dispersed adds the NaClO solution of chitinous 5% effective chlorine of 5mL and starts oxidation, uses pH titration system under room temperature
PH is maintained by dropping 0.5M NaOH in system 10, when system no longer consumes NaOH, add several ethanol and terminate reaction,
With 0.5M HCl, pH value of solution being adjusted to 7,12000 turn of 5 min repeated centrifugation washing is to neutral, and tilt-pour process removes supernatant, obtains
Water-insoluble fraction, the water-insoluble fraction obtained is that TEMPO aoxidizes chitin.With distilled water with the ratio of solid-to-liquid ratio 1:100 by upper
State the TEMPO oxidation chitin dispersion prepared homogeneous, and carry out further being homogenized supersound process, final centrifuging and taking supernatant
Obtain the chitin nanofiber dispersion liquid of negative electricity characteristic.TEMPO oxidation elecrtonegativity chitin nanofiber dispersion liquid number shines
Sheet and chitin nanofiber transmission electron microscope picture (left side: dispersion liquid digital photograph, the right side: nanofiber transmission electron microscope as shown in Figure 1
Figure), Fig. 1 shows, chitin nanofiber dispersion liquid light transmission is good, and the chitin nanofiber of cross section width 5-50nm is stably deposited
It is in dispersion liquid system, and possesses the zeta-current potential of negative value, it was demonstrated that the elecrtonegativity feature of chitin nanofiber, simultaneously
Also being to maintain one of factor of chitin nanofiber stable dispersion, therefore, TEMPO oxidation elecrtonegativity chitin nanofiber divides
Scattered liquid has good transmittance and stability.
Embodiment 3 prepares elecrtonegativity chitin nanofiber dispersion liquid with sodium hydroxide for weak alkaline medium
Weigh 0.016g TEMPO, 0.1 g NaBr, the purification chitin of 1g dry weight be separately added into 200mL beaker stirs molten
Solve.The backward system that is uniformly dispersed adds the NaClO solution of chitinous 5% effective chlorine of 5mL and starts oxidation, titrates with pH under room temperature
System drips 0.5M NaOH in system and pH is maintained 10, when system no longer consumes NaOH, adds several ethanol and terminates anti-
Should, with 0.5M HCl, pH value of solution being adjusted to 7,1200 turns of 5min repeated centrifugation washings are to neutral, and tilt-pour process removes supernatant, obtains
The water-insoluble fraction that water-insoluble fraction obtains is that TEMPO aoxidizes chitin.With distilled water with the ratio of solid-to-liquid ratio 1:100 by above-mentioned
The TEMPO oxidation chitin dispersion prepared is homogeneous, regulates pH value of solution to about 9 with the sodium hydroxide solution of 0.5 M, goes forward side by side
One step carries out being homogenized supersound process, and final centrifuging and taking supernatant obtains with the scattered chitin with negative electricity characteristic of sodium hydroxide
Nanofiber dispersion liquid.
Embodiment 4 prepares elecrtonegativity chitin nanofiber hydrogels with hydrochloric acid for coagulating bath
The elecrtonegativity chitin nanofiber dispersion liquid of configuration 0.6%, takes 20 mL elecrtonegativity chitin nanofiber dispersion liquid and puts
In 50 mL beakers, separately take 250 mL beakers and place the hydrochloric acid solution of 20 g 5 M, be positioned over small beaker in large beaker to protect
Fresh bag seals, and takes out small beaker, prepare homogeneous and that printing opacity is good elecrtonegativity chitin nanofiber water after processing 12 h
Gel.Elecrtonegativity chitin nanofiber hydrogels digital photograph is as in figure 2 it is shown, Fig. 2 left-handed watch bright chitin nanofiber water-setting
Glue possesses good independence and mechanical strength, and Fig. 2 right side shows that chitin nanofiber hydrogels possesses preferable light transmission, because of
This, TEMPO oxidation elecrtonegativity chitin nanofiber hydrogels has preferable light transmission and good mechanical strength.
Embodiment 5 prepares elecrtonegativity chitin nanofiber hydrogels with acetic acid coagulating bath
The elecrtonegativity chitin nanofiber dispersion liquid of configuration 0.6%, takes 20 mL elecrtonegativity chitin nanofiber dispersion liquid and puts
In 50 mL beakers, separately take 250 mL beakers and place the acetum of 20 g 5 M, be positioned over small beaker in large beaker to protect
Fresh bag seals, and takes out small beaker, prepare homogeneous and that printing opacity is good elecrtonegativity chitin nanofiber water after processing 12 h
Gel.
Embodiment 6 prepares the chitin nanofiber hydrogels of 0.2% concentration with hydrochloric acid steam bath
Configuration 5M hydrochloric acid solution and the elecrtonegativity chitin nanofiber dispersion liquid of 0.2%, take 20mL elecrtonegativity chitin Nanowire
Dimension dispersion liquid is placed in 50mL beaker, separately takes 250mL beaker and pours 20mL above-mentioned configuration hydrochloric acid solution into, is positioned over greatly by small beaker
Beaker seals with preservative film, takes out small beaker after processing 24h, prepare homogeneous and that printing opacity is good elecrtonegativity chitin and receive
Rice fiber water gel.
Embodiment 7 prepares the chitin nanofiber hydrogels of 0.5% concentration with hydrochloric acid steam bath
Configure the elecrtonegativity chitin nanofiber dispersion liquid of 5 M hydrochloric acid solutions and 0.5%, take 20mL elecrtonegativity chitin nanometer
Fiber dispersion is placed in 50 mL beakers, separately takes 250 mL beakers and pours 20 mL above-mentioned configuration hydrochloric acid solution into, is put by small beaker
It is placed in large beaker and seals with preservative film, take out small beaker after processing 24h, prepare homogeneous and that printing opacity is good elecrtonegativity several
Fourth matter nanofiber hydrogels.
Embodiment 8 prepares the chitin nanofiber hydrogels of 2.0% concentration with hydrochloric acid steam bath
Configuration 5M hydrochloric acid solution and the elecrtonegativity chitin nanofiber dispersion liquid of 2.0%, take 20 mL elecrtonegativity chitin nanometers
Fiber dispersion is placed in 50mL beaker, separately takes 250mL beaker and pours 20mL above-mentioned configuration hydrochloric acid solution into, is positioned over by small beaker
Large beaker seals with preservative film, takes out small beaker after processing 24h, prepare homogeneous and that printing opacity is good elecrtonegativity chitin
Nanofiber hydrogels.
Embodiment 9 prepares chitin nanofiber aeroge with lyophilization for drying means
By the chitin nanofiber physical hydrogel produced with liquid nitrogen flash freezer, and lyophilization 3 days, prepare chitin and receive
Rice fiber aeroge.Elecrtonegativity chitin nanofiber aeroge digital photograph, as shown in Fig. 3 left side, elecrtonegativity chitin nanometer
Fiber aeroge scanning electron microscope (SEM) photograph, as shown in Fig. 3 right side, Fig. 3 shows TEMPO oxidation elecrtonegativity chitin nanofiber aeroge tool
Abundant fibrillar meshwork structure and aeroge is had to have the advantages that light weight is high-strength.
Although the present invention describes according to above-mentioned detailed description of the invention, but the invention thought of the present invention not only limiting
Invent in this, the repacking of any utilization inventive concept, all will include in this patent scope of patent protection.
Claims (9)
1. the preparation method of an elecrtonegativity chitin nanofiber hydrogels, it is characterised in that comprise the following steps:
1) take chitin raw material and carry out pretreatment, it is thus achieved that chitin slurry；
2) the chitin slurry that step 1) obtains is through 2, and 2,6,6-tetramethyl piperidines-nitrogen-oxide catalyst oxidation system processes, and obtains
Obtain elecrtonegativity chitin；
3) step 2) the elecrtonegativity chitin that obtains prepares elecrtonegativity chitin through mechanical treatment in the solution of pH 5-10
Nanofiber dispersion liquid；
4) the elecrtonegativity chitin nanofiber dispersion liquid that step 3) obtains processes preparation through acid coagulating bath or acid vapors bath
Obtain the elecrtonegativity chitin nanofiber hydrogels of physical crosslinking.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
Being: in step 1), described chitin raw material includes Crusta Penaeus seu Panulirus, Carapax Eriocheir sinensis.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
It is: step 2) in, 2,2,6,6-tetramethyl piperidines-nitrogen-oxide catalyst oxidation system is: relative to chitin dry weight,
TEMPO addition is 0.05-0.5 mmol/g, and NaBr addition is 0.5-5 mmol/g, and NaClO addition is 2-8 mmol/
G chitin, pH is 10.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
Being: in step 3), described solution is weak alkaline aqueous solution or water.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
Being: in step 4), acid coagulating bath includes acetic acid coagulating bath, hydrochloric acid coagulating bath.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
Being: in step 4), acid vapors bath includes acetic acid steam bath, and hydrochloric acid vapour is bathed.
Preparation elecrtonegativity chitin nanofiber hydrogels the most according to claim 1 and the method for aeroge, its feature
Being: in step 4), acid coagulating bath and steam bath process time are 6-120h.
8. the preparation method of an elecrtonegativity chitin nanofiber aeroge, it is characterised in that prepared by claim 1
Elecrtonegativity chitin nanofiber hydrogels drying dehydration after obtain.
The preparation method of elecrtonegativity chitin nanofiber aeroge the most according to claim 8, it is characterised in that: described
Drying means is lyophilization, supercritical drying.
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106893116A (en) * | 2017-02-24 | 2017-06-27 | 浙江和也健康科技有限公司 | A kind of preparation method of cellulose nano-fibrous biomass gel and aeroge |
| CN107233356A (en) * | 2017-06-13 | 2017-10-10 | 南京林业大学 | Chitin nanofiber compositions and its application with fat-reducing and antihyperglycemic |
| CN108192113A (en) * | 2018-01-09 | 2018-06-22 | 南京林业大学 | A kind of method of the preparation and its redisperse of highly concentrated hygrometric state and dry state chitin nanofiber/whisker |
| CN108774289A (en) * | 2018-07-03 | 2018-11-09 | 南京林业大学 | Preparation method, high-carboxyl-content chitin nanofiber dispersion liquid and the application of high-carboxyl-content chitin nanofiber dispersion liquid |
| CN108795911A (en) * | 2018-07-03 | 2018-11-13 | 南京林业大学 | Chitin deacetylase, chitin nanofiber dispersion liquid and its preparation method and application |
| CN108822309A (en) * | 2018-05-29 | 2018-11-16 | 南京林业大学 | A kind of preparation method of the nanofiber with sustained release performance/microemulsion composite hydrogel |
| CN109251330A (en) * | 2018-08-08 | 2019-01-22 | 华南理工大学 | Nano-chitosan-PVA hydrogel and its preparation method and application |
| CN109836607A (en) * | 2019-01-16 | 2019-06-04 | 中国制浆造纸研究院有限公司 | A kind of preparation method improving cellulose aerogels pore structure |
| CN110003535A (en) * | 2019-04-12 | 2019-07-12 | 南京林业大学 | It is a kind of based on solvent-induced hyaluronic acid-based shape memory gel and preparation method thereof |
| CN112940287A (en) * | 2021-02-03 | 2021-06-11 | 武汉大学 | Shape memory chitosan hydrogel and preparation method thereof |
| CN114292447A (en) * | 2021-11-24 | 2022-04-08 | 南京林业大学 | Preparation of nano-chitin-based porous conductive elastic foam by Pickering foam template method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105820352A (en) * | 2016-04-06 | 2016-08-03 | 南京林业大学 | Method for preparing electropositive chitin nanofiber hydrogel and aerogel |
-
2016
- 2016-08-04 CN CN201610630545.XA patent/CN106220867A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105820352A (en) * | 2016-04-06 | 2016-08-03 | 南京林业大学 | Method for preparing electropositive chitin nanofiber hydrogel and aerogel |
Non-Patent Citations (2)
| Title |
|---|
| YAN ZHANG ET AL.: ""Preparation, assessment, and comparison of α-chitin nano-fiber films with different surface charges"", 《NANOSCALE RESEARCH LETTERS》 * |
| 张燕等: ""晶体表面修饰制备几丁质纳米纤维的研究进展"", 《林产化学与工业》 * |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN107233356A (en) * | 2017-06-13 | 2017-10-10 | 南京林业大学 | Chitin nanofiber compositions and its application with fat-reducing and antihyperglycemic |
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