CN106215113A - For treating the medicine of damp-heat type dysmenorrhea - Google Patents

For treating the medicine of damp-heat type dysmenorrhea Download PDF

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CN106215113A
CN106215113A CN201610728177.2A CN201610728177A CN106215113A CN 106215113 A CN106215113 A CN 106215113A CN 201610728177 A CN201610728177 A CN 201610728177A CN 106215113 A CN106215113 A CN 106215113A
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王立丽
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract

The invention discloses a kind of medicine for treating damp-heat type dysmenorrhea, mainly it is made up of the raw material of following weight parts proportioning: Rhizoma Cyperi 6 12 parts, Herba Leonuri 10 15 parts, Radix Rehmanniae 9 18 parts, Radix Angelicae Sinensis 9 18 parts, the Radix Paeoniae Alba 9 18 parts, Rhizoma Chuanxiong 6 12 parts, 6 12 parts of Flos Carthami, 6 12 parts of Semen Persicae, Rhizoma Curcumae 48 parts, Rhizoma Corydalis 9 18 parts, Semen Coicis 12 21 parts.The present invention is for treating the medicine of damp-heat type dysmenorrhea, choose 11 kinds of natural Chinese medicine scientific compatibility, formula is simple, and each crude drug synergism plays removing damp-heat, the effect of blood-activating analgetic, instant effect, treating both the principal and secondary aspects of a disease, has no side effect, and its preparation method is simple, taking convenience, low cost, effective percentage reaches more than 98%.

Description

For treating the medicine of damp-heat type dysmenorrhea
Technical field
The present invention relates to Chinese medicine, a kind of medicine for treating damp-heat type dysmenorrhea.
Background technology
Dysmenorrhea is common gynecological disease and frequently-occurring disease, and the cause of disease is many, and pathogenesis is complicated, and repeatability is big, treats thorny, the most unmarried Women and menarche maiden the most universal, before and after showing as menstrual period or passing through, periodically there is hypogastric region distending pain, cold type of pain, burn Bitterly, twinge, dull pain, pendant pain, angor, spasmic pain, lancinating pain, pain is extended down to sacrum lower back, even relate to thigh and Foot, is often accompanied by General Symptoms: distending pain of the breast, agitation uncomfortable in chest, sad irritability, the heart shy insomnia, headache and dizzy, nausea and vomiting, stomach The symptoms such as pain diarrhoea, fatigue and weakness, pale complexion, extremity are ice-cold, dripping cold sweat, collapse faintness.High, the scope of its morbidity it Extensively, the cycle is closely, misery is big, has had a strong impact on the working and learning of numerous women, has reduced the quality of life.
At present, formula and the various medicine of clinical treatment damp-heat type dysmenorrhea have a lot, but, comparatively speaking, control The cycle treated is the longest, takes effect inconspicuous, there is also sensory difference to a certain extent simultaneously.
Summary of the invention
It is an object of the invention to provide a kind of good effect, short treating period, low cost, have no side effect for treating damp-heat type The medicine of dysmenorrhea.
The technical scheme realizing the object of the invention is:
A kind of medicine for treating damp-heat type dysmenorrhea, is mainly made up of the raw material of following weight parts proportioning:
Rhizoma Cyperi 6-12 part, Herba Leonuri 10-15 part, Radix Rehmanniae 9-18 part, Radix Angelicae Sinensis 9-18 part, Radix Paeoniae Alba 9-18 part, Rhizoma Chuanxiong 6-12 Part, Flos Carthami 6-12 part, Semen Persicae 6-12 part, Rhizoma Curcumae 4-8 part, Rhizoma Corydalis 9-18 part, Semen Coicis 12-21 part.
The above-mentioned medicine for treating damp-heat type dysmenorrhea, optimum weight part proportioning of each raw material is:
Rhizoma Cyperi 9 parts, Herba Leonuri 12 parts, Radix Rehmanniae 12 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Chuanxiong 9 parts, 9 parts of Flos Carthami, Semen Persicae 9 Part, Rhizoma Curcumae 6 parts, Rhizoma Corydalis 12 parts, Semen Coicis 18 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, after adding alcohol dipping 5-7 days that 3-5 times of concentration of material quantity is 40-60%, filter and remove residue, decompression filtrate recycling ethanol is extremely Taste without alcohol, obtains concentrated solution 60-100 part, standby；
(2) in the concentrated solution that step (1) prepares, add 800-1000 part water and 0.8-1.2 part potassium sorbate, stir evenly, quiet Put 20-30h, filter, obtain filtrate, standby；
(3) separately with 80-100 part sucrose, add 120-150 part water boil 30-40min, filter, standby；
(4) the filtrate mixing of step (2) and (3) is placed in container, adds 800-1000 part water, bottle after cooling, seal After carry out sterilization treatment, make product.
In the present invention, the pharmacology of each crude drug, effect are as follows:
Rhizoma Cyperi: have soothing the liver, yin nourishing, regulate the flow of vital energy, effect of pain relieving, be used for treating the menoxenia of hepatic depression and blood deficiency, abdominal pain during menstruation.
Herba Leonuri: there is promoting blood flow to regulate menstruation, inducing diuresis to remove edema, effect of heat-clearing and toxic substances removing.For menoxenia, dysmenorrhea amenorrhea, dislike Reveal endless, edema oliguria, sore swollen toxin.
Radix Rehmanniae: there is heat clearing away, YIN nourishing of promoting the production of body fluid, the effect nourished blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, Menoxenia, frequent fetal movement, the moon hinders constipation.
Radix Angelicae Sinensis: have and enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, cure mainly all cards of blood deficiency；Menoxenia；Warp Close；Dysmenorrhea；Lump in the abdomen knot is poly-；Metrorrhagia；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness of the skin；Dryness of the intestine dyschezia；Weight after bloody dysentery；Ulcer sores；Fall and flutter Damage.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, it is slightly cold, there is easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing receives the effects such as antiperspirant, it is adaptable to the deficiency of YIN Heating, menoxenia, the chest and abdomen pain over the hypochondriac region, extremity contraction urgency, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.
Rhizoma Chuanxiong: cure mainly menoxenia；Amenorrhea dysmenorrhea；Puerperal the stasis of blood stagnant raw meat pain；Lump in the abdomen lump；Pain in chest and hypochondrium；Headache dizziness；Wind Cold-damp numbness；Traumatic injury；Ulcer sores etc..
Flos Carthami: warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury Damage.
Semen Persicae: there is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess Acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.
Rhizoma Curcumae: cure mainly " coagulation of QI-blood, trusted subordinate's distending pain, lump in the abdomen, accumulation, dyspepsia does not disappears, women's blood stasis amenorrhea, traumatic injury Have a pain." tuber claims " green filament Radix Curcumae ", has promoting QI circulation for relieving depression, removing blood stasis with potent drugs, the function of pain relieving.
Rhizoma Corydalis: have and invigorate blood circulation, circulation of qi promoting, effect of pain relieving.For breast the side of body, epigastric pain, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, Postpartum stagnation, tumbling and swelling.
Semen Coicis: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.Can be used for treating edema, tinea pedis, dysuria.
The present invention, for treating the medicine of damp-heat type dysmenorrhea, chooses 11 kinds of natural Chinese medicine scientific compatibility, and formula is simple, each former Material medicine synergism plays removing damp-heat, the effect of blood-activating analgetic, instant effect, and treating both the principal and secondary aspects of a disease has no side effect, and it is prepared Method is simple, taking convenience, low cost.
Detailed description of the invention
Below in conjunction with embodiment, present invention is further described, but is not limitation of the invention.
Embodiment 1
A kind of medicine for treating damp-heat type dysmenorrhea, is mainly made up of the raw material of following weight parts proportioning:
Rhizoma Cyperi 6kg, Herba Leonuri 10kg, Radix Rehmanniae 9kg, Radix Angelicae Sinensis 9kg, Radix Paeoniae Alba 9kg, Rhizoma Chuanxiong 6kg, Flos Carthami 6kg, Semen Persicae 6kg, Rhizoma Curcumae 4kg, Rhizoma Corydalis 9kg, Semen Coicis 12kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 3 times of concentration of material quantity is the alcohol dipping of 40% after 5 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 60kg, standby；
(2) in the concentrated solution that step (1) prepares, add 800kg water and 0.8kg potassium sorbate, stir evenly, stand 20h, mistake Filter, obtains filtrate, standby；
(3) separately use 80kg sucrose, add 120kg water boil 30min, filter, standby；
(4) filtrate of step (2) and (3) mixed be placed in container, add 800kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 2
A kind of medicine for treating damp-heat type dysmenorrhea, is mainly made up of the raw material of following weight parts proportioning:
Rhizoma Cyperi 9kg, Herba Leonuri 12kg, Radix Rehmanniae 12kg, Radix Angelicae Sinensis 12kg, Radix Paeoniae Alba 12kg, Rhizoma Chuanxiong 9kg, Flos Carthami 9kg, Semen Persicae 9kg, Rhizoma Curcumae 6kg, Rhizoma Corydalis 12kg, Semen Coicis 18kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 4 times of concentration of material quantity is the alcohol dipping of 50% after 6 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 80kg, standby；
(2) in the concentrated solution that step (1) prepares, add 900kg water and 1kg potassium sorbate, stir evenly, stand 25h, filter, Obtain filtrate, standby；
(3) separately use 90kg sucrose, add 135kg water boil 35min, filter, standby；
(4) filtrate of step (2) and (3) mixed be placed in container, add 900kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 3
A kind of medicine for treating damp-heat type dysmenorrhea, is mainly made up of the raw material of following weight parts proportioning:
Rhizoma Cyperi 12kg, Herba Leonuri 15kg, Radix Rehmanniae 18kg, Radix Angelicae Sinensis 18kg, Radix Paeoniae Alba 18kg, Rhizoma Chuanxiong 12kg, Flos Carthami 12kg, Fructus Persicae Core 12kg, Rhizoma Curcumae 8kg, Rhizoma Corydalis 18kg, Semen Coicis 21kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 5 times of concentration of material quantity is the alcohol dipping of 60% after 7 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 100kg, standby；
(2) in the concentrated solution that step (1) prepares, add 1000kg water and 1.2kg potassium sorbate, stir evenly, stand 30h, mistake Filter, obtains filtrate, standby；
(3) separately use 100kg sucrose, add 150kg water boil 40min, filter, standby；
(4) filtrate of step (2) and (3) mixed be placed in container, add 1000kg water, bottle after cooling, seal laggard Row sterilization treatment, makes product.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, select to accept 150 examples in patient for medical treatment, to medicine of the present invention Curative effect carry out clinical observation.In age 13-30 year, it is randomly divided into 3 groups, often organizes 50 examples, respectively experimental group 1-3 group.
Experimental group 1-3 group takes the medicine of embodiment 1-3 respectively, three times a day, takes 5g orally every time, within one week, is a course for the treatment of, The course for the treatment of is 2 weeks.The most effective 145 examples, effective 147 examples, cure 142 examples, invalid 3 examples, cure rate 95%, effective percentage 98%.

Claims (7)

1., for treating a medicine for damp-heat type dysmenorrhea, it is characterized in that: be mainly made up of the raw material of following weight parts proportioning:
Rhizoma Cyperi 6-12 part, Herba Leonuri 10-15 part, Radix Rehmanniae 9-18 part, Radix Angelicae Sinensis 9-18 part, Radix Paeoniae Alba 9-18 part, Rhizoma Chuanxiong 6-12 part, red Flower 6-12 part, Semen Persicae 6-12 part, Rhizoma Curcumae 4-8 part, Rhizoma Corydalis 9-18 part, Semen Coicis 12-21 part.
2. to require the medicine for treating damp-heat type dysmenorrhea described in 1 according to right, it is characterized in that: the weight portion of each raw material is joined Than being:
Rhizoma Cyperi 9 parts, Herba Leonuri 12 parts, Radix Rehmanniae 12 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Chuanxiong 9 parts, 9 parts of Flos Carthami, 9 parts of Semen Persicae, Rhizoma Curcumae 6 parts, Rhizoma Corydalis 12 parts, Semen Coicis 18 parts.
3. to require the preparation method of the medicine for treating damp-heat type dysmenorrhea described in 1 according to right, it is characterized in that: specifically walk Rapid as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, be mixed together and be placed in container, add After entering alcohol dipping 5-7 days of material quantity 3-5 times, filter and remove residue, decompression filtrate recycling ethanol, to without alcohol taste, obtains concentrated solution 60- 100 parts, standby；
(2) in the concentrated solution that step (1) prepares, add water and potassium sorbate, stir evenly, stand 20-30h, filter, obtain filtrate, standby With；
(3) separately with sucrose, add water boil 30-40min, filter, standby；
(4) filtrate of step (2) and (3) mixed be placed in container, add water, bottle after cooling, seal after carry out sterilization treatment, Make product.
The preparation method of the medicine for treating damp-heat type dysmenorrhea the most according to claim 3, is characterized in that: described step (1) concentration of the ethanol added in is 40-60%.
The preparation method of the medicine for treating damp-heat type dysmenorrhea the most according to claim 3, is characterized in that: described step (2) in, the addition of water is 800-1000 part, and the addition of potassium sorbate is 0.8-1.2 part.
The preparation method of the medicine for treating damp-heat type dysmenorrhea the most according to claim 3, is characterized in that: described step (3) amount of the sucrose in is 80-100 part, and the amount of water is 120-150 part.
The preparation method of the medicine for treating damp-heat type dysmenorrhea the most according to claim 3, is characterized in that: described step (4) in, the addition of water is 800-1000 part.
CN201610728177.2A 2016-08-25 2016-08-25 For treating the medicine of damp-heat type dysmenorrhea Pending CN106215113A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272774A (en) * 2018-03-15 2018-07-13 广西中医药大学 A kind of graphene treatment dysmenorrhea plaster and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102049001A (en) * 2009-10-28 2011-05-11 王宝凤 Formula of traditional Chinese medicine for treating primary dysmenorrhea
CN104984256A (en) * 2015-07-27 2015-10-21 谢丽蓉 Drug for treatment of damp heat and blood stasis type dysmenorrhea

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102049001A (en) * 2009-10-28 2011-05-11 王宝凤 Formula of traditional Chinese medicine for treating primary dysmenorrhea
CN104984256A (en) * 2015-07-27 2015-10-21 谢丽蓉 Drug for treatment of damp heat and blood stasis type dysmenorrhea

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272774A (en) * 2018-03-15 2018-07-13 广西中医药大学 A kind of graphene treatment dysmenorrhea plaster and preparation method thereof

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Application publication date: 20161214