CN106214460B - A kind of eye syringe - Google Patents
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- CN106214460B CN106214460B CN201610827123.1A CN201610827123A CN106214460B CN 106214460 B CN106214460 B CN 106214460B CN 201610827123 A CN201610827123 A CN 201610827123A CN 106214460 B CN106214460 B CN 106214460B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H35/00—Baths for specific parts of the body
- A61H35/02—Baths for specific parts of the body for the eyes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/01—Constructive details
- A61H2201/0157—Constructive details portable
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Abstract
The invention discloses a kind of eye syringes, belong to medical instruments field.A kind of eye syringe of the invention, including medicinal liquid cavity, collyrium is filled in the medicinal liquid cavity, the medicinal liquid cavity bottom opening, the medicinal liquid cavity opening is fixedly connected with button cover top, the button cover top opening is less than bottom opening, and the medicinal liquid cavity opening is equipped with baffle, and the baffle closes medicinal liquid cavity opening.A kind of eye syringe of the invention has without squeezing, the characteristics of avoiding in use causing stress eye, bring sense of discomfort, collyrium is preferably allowed sufficiently to rinse eye.
Description
Technical field
The present invention relates to a kind of medical instrument, especially a kind of eye syringe.
Background technique
U.S. pupil can be such that eyes increase, and so that entire people is seemed spiritual many, the deep welcome by modern.But long-term pendant
Dai Meitong can make eyes feel dry and astringent, easily cause keratitis, and even one's eyes became bloodshot, serious to will lead to the change of cornea anoxic
Shape and eye infection cause the serious eye diseases such as perforation of cornea, even result in eyes permanent loss vision.Eye is washed by eye syringe
It can play cleaning eye, improve that eyes are dry and astringent, the symptoms such as congested, but existing eye syringe is that a flexible silica gel holds
Device pours into medical fluid in container, and collyrium is rinsed eye by squeezing medical fluid.But during extruding, the pressure of generation
Power can bring biggish sense of discomfort to eye, and physiology natural reaction can shut eyes, can not play the work of good cleaning eye
With.
Summary of the invention
Goal of the invention of the invention is: in view of the above problems, providing one kind without squeezing, avoids using
Eye is caused stress in journey, brings sense of discomfort, collyrium is preferably allowed sufficiently to rinse the eye syringe of eye.
The technical solution adopted by the invention is as follows:
A kind of eye syringe of the invention, including medicinal liquid cavity fill collyrium in the medicinal liquid cavity, and the medicinal liquid cavity bottom is opened
Mouthful, the medicinal liquid cavity opening is fixedly connected with button cover top, and the button cover top opening is less than bottom opening, the medicinal liquid cavity
Opening is equipped with baffle, and the baffle closes medicinal liquid cavity opening.
By adopting the above-described technical solution, when in use, button is covered in into eye, then baffle is removed, can allow medicine
Liquid is flowed out from medicinal liquid cavity, to complete the cleaning to eye, structure is simple, easy to use.
A kind of eye syringe of the invention, the button cover include upper buckle cover and lower buckle cover, the upper buckle cover and lower part
Button cover is fabricated from a flexible material, and the upper buckle cover and lower buckle cover are flexibly connected, and the lower buckle cover can be with tie point
For midpoint flip-over.
By adopting the above-described technical solution, being acted on downwards after button cover is buckled in eye, tie point rotation, so that medical fluid
Distance of the chamber apart from eye shortens, and eye is come into full contact with medical fluid, and the medical fluid in medicinal liquid cavity is facilitated to carry out eye
Preferably rinse.
A kind of eye syringe of the invention, inclined face at the button cover opening, the button cover have most longwell and most shortwall,
The inclined surface and horizontal plane have 13 ° of angles, and the upper buckle cover is identical as the wall length of lower buckle cover.
By adopting the above-described technical solution, make button cover be more in line with human body eye shape feature, can preferably with
Eye is bonded, and avoiding detaining cover when in use can not fasten, and medical fluid is caused to trickle everywhere.
A kind of eye syringe of the invention, the flexible material are made of silica gel, and the flexible material surface is covered with antibiotic layer,
The antibiotic layer with a thickness of 300 μm, the antibiotic layer is made of acrylate grafted silica.
By adopting the above-described technical solution, antibacterial film not only has certain antibacterial action, while there is good dredge
It is aqueous, avoid water dust etc. from being attached to eye syringe surface, into eye, after placing 10h at room temperature, eye syringe surface bacteria is total
Number is 160cfu/g.
A kind of eye syringe of the invention, the upper buckle cover inner wall are fixedly connected with two eye speculums, and two eye speculum is oppositely arranged
On the inner wall of button cover most shortwall and most longwell, two eye speculum is set to above tie point.
By adopting the above-described technical solution, after button cover is buckled in eye, will button cover when rotating down, two eye speculums can will
Upper eyelid and palpebra inferior strut, and eyes physiological reflex after contacting medical fluid is avoided to close one's eyes, so that medical fluid contacts eyelid first,
The cleaning capacity of medical fluid is caused to decline.
A kind of eye syringe of the invention, each eye speculum are sheet, and the eye speculum lower end has protrusion, the protrusion
Height is 0.7mm, and the eye speculum is gradually smoothly connected with button cover inner wall by lower end to upper end.
By adopting the above-described technical solution, eye speculum acts softly during supportting eye, avoid bringing eye injury.
One end of a kind of eye syringe of the invention, the baffle is fixedly connected with medical fluid cavity wall, the baffle it is another
End extends to outside medicinal liquid cavity across medical fluid cavity outer wall, and the baffle and medical fluid cavity wall connecting pin are equipped with breakpoint.
Baffle is removed by adopting the above-described technical solution, facilitating, eye is buckled in when button covers, head is raised, it is pico- to use
Power can disconnect the connection of baffle and medicinal liquid cavity, so that medical fluid flows out.
A kind of eye syringe of the invention, the collyrium is by 78 parts of physiological saline of mass parts, 26 parts of methylcellulose, and 13 parts
Sodium Hyaluronate, 13 parts of taurines, 8 parts of triazole thioether indole derivatives, 5 parts of [Ni (en)3](L)2·3H2O, 9 parts of Rhizoma Chuanxiongs
Extracting solution and 7 parts of preservative compositions, the structural formula of the triazole thioether indole derivatives are。
By adopting the above-described technical solution, to staphylococcus aureus, escherichia coli, bacillus subtilis, raw spore
Clostridium, Candida albicans, aspergillus niger and pseudomonas aeruginosa show good deactivation, can be in low concentration condition
Under, it is small to the stimulation of eyes, it is 30.2% to the inactivation ratio of staphylococcus aureus in 10s, the inactivation to escherichia coli
Rate is 27.4%, and the inactivation ratio to bacillus subtilis is 23.9%, and the inactivation ratio to clostridium sporogenes is 31.5%, to Candida albicans
The inactivation ratio of bacterium is 22.6%, and the inactivation ratio to aspergillus niger is 26.4%, and the inactivation ratio to pseudomonas aeruginosa is 20.8%.
A kind of eye syringe of the invention, the collyrium pass through60The sterilizing of Co- gamma Rays, radiation intensity 15kGy,
Radiation dose rate is 3.6kGy/h.
By adopting the above-described technical solution, by radiation sterilization, sterilization effect is good, while to each group molecular structure five
It influences, avoids in Rhizoma Chuanxiong extract thermal stability is heated compared with difference subspace from decomposing.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
1, it without squeezing, avoids in use causing stress eye, brings sense of discomfort, preferably collyrium is allowed to fill
Divide and rinses eye.
2, after button cover is buckled in eye, when button cover is rotated down, two eye speculums can strut upper eyelid and palpebra inferior, keep away
Exempt from eyes physiological reflex after contacting medical fluid to close one's eyes, so that medical fluid contacts eyelid first, under the cleaning capacity for leading to medical fluid
Drop.
3, to staphylococcus aureus, escherichia coli, bacillus subtilis, clostridium sporogenes, Candida albicans, aspergillus niger
Good deactivation is shown with pseudomonas aeruginosa, it can be small to the stimulation of eyes under the conditions of low concentration.
Detailed description of the invention
Fig. 1 is a kind of eye syringe structural schematic diagram.
Marked in the figure: 1 is medicinal liquid cavity, 2 be baffle, and 3 be eye speculum.
Specific embodiment
With reference to the accompanying drawing, the present invention is described in detail.
In order to which the objects, technical solutions and advantages of invention are more clearly understood, with reference to the accompanying drawings and embodiments, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
Embodiment 1
As shown in Figure 1, a kind of eye syringe, including medicinal liquid cavity 1, collyrium is filled in medicinal liquid cavity 1,1 bottom opening of medicinal liquid cavity,
1 opening of medicinal liquid cavity is fixedly connected with button cover top, and button cover top opening is less than bottom opening, and 1 opening of medicinal liquid cavity is equipped with gear
Plate 2, baffle 2 close 1 opening of medicinal liquid cavity.Button cover includes upper buckle cover and lower buckle cover, and upper buckle cover and lower buckle cover are equal
It is fabricated from a flexible material, upper buckle cover and lower buckle cover are flexibly connected, and lower buckle cover can be flipped outward by midpoint of tie point.
Inclined face at cover opening is detained, button cover has most longwell and most shortwall, and inclined surface and horizontal plane have 13 ° of angles, upper buckle cover
It is identical as the wall length of lower buckle cover.Flexible material is made of silica gel, and flexible material surface is covered with antibiotic layer, antibiotic layer with a thickness of
300 μm, antibiotic layer is made of acrylate grafted silica.Upper buckle cover inner wall is fixedly connected with two eye speculums 3, two eye speculums
3 are relatively arranged on the inner wall of button cover most shortwall and most longwell, and two eye speculums 3 are set to above tie point.Each eye speculum 3 is piece
Shape, 3 lower end of eye speculum have a protrusion, and raised height is 0.7mm, eye speculum 3 by lower end to upper end gradually smoothly with button cover inner wall phase
It connects.One end of baffle 2 is fixedly connected with 1 inner wall of medicinal liquid cavity, and the other end of baffle 2 passes through 1 outer wall of medicinal liquid cavity, extends to medicinal liquid cavity 1
Outside, baffle 2 and 1 inner wall connecting pin of medicinal liquid cavity are equipped with breakpoint.
Embodiment 2
Acrylate grafted silica preparation method:
The synthesis of acrylic resin: being added 50 g toluene in four-hole bottle, is heated to 80 C, 0.5 h of nitrogen deoxygenation.By first
Base acrylic acid fourth 8 g, 1 g of glycidyl methacrylate, 0.97 g of deionized water, methyl methacrylate 49 and azo two
0.17 g of isobutyronitrile, which is uniformly mixed to initiator, to be completely dissolved.Monomer mixed solution is added to 50 mI.In disposable syringe,
Monomer is added in four-hole bottle in 3 h using syringe pump.10 g first of 0.09 g azodiisobutyronitrile are added after 1 h of constant temperature
Benzole soln, 0.5 h is interior to be added with syringe pump.2 h of subsequent isothermal reaction, closes heat source.After reaction vessel cooling after, utilization just oneself
Alkane purifies acrylic resin, and drying is stand-by.Acrylic resin is mixed with organic siliconresin later, at 80 DEG C drying to
With.
The modification of silica: 100 g toluene and 5 g silica are taken, silica dispersions are configured to.Utilize cell
Pulverizer ultrasonic disperse (3 s, 180 times, 600W), then plus 2 g silane coupling agents into four-hole bottle, flow back 8 h.Use soxhlet extraction
Device cleans residual silane coupling agent with 8 h of refluxing toluene.
The preparation of composite material: by a certain proportion of modified Nano SiO2It is distributed in certain toluene first, using super
Sonic disintegrator (3 s, 180 times, 600 W), is prepared nanoparticle dispersion liquid；Configure certain density acrylic resin and
Mixed liquor and nanoparticle dispersion liquid magneton are stirred 10 min by organic siliconresin mixed liquor, obtain acrylate grafting two
Silica.
Embodiment 3
By 78 parts of physiological saline of mass parts, 26 parts of methylcellulose, 13 parts of Sodium Hyaluronates, 13 parts of taurines, 8 part three
Nitrogen azoles thioether indole derivatives, 5 parts of [Ni (en)3](L)2·3H2O, 9 parts of Rhizoma Chuanxiongs
Extracting solution and 7 portions of preservatives uniformly mix at normal temperature, wherein preservative is by 8 parts of potassium sorbates of mass parts, 12 parts of nipalgin second
Ester, 3 parts of sodium benzoates and 6 parts of sodium sulfite compositions, are after mixing 15kGy in radiation intensity, radiation dose rate is
Pass through under conditions of 3.6kGy/h60The sterilizing of Co- gamma Rays.
[Ni(en)3](L)2·3H2The preparation of O: 0.5mmol nickel sulfate is taken to be dissolved in the ethyl alcohol-that the volume ratio of 10mL is 1:l
In water mixed solvent, lmmol HL is separately taken to be dissolved in 10 mL ethanol-waters, the pH value of solution is adjusted with sodium hydroxide solution
It is 5, is gradually dropped in above-mentioned solution.4 h are stirred at room temperature, there are a large amount of greenish precipitates to generate, precipitating is filtered, l:l is used
Ethanol-water mixed solvent wash 3 times, normal-temperature vacuum is dry.Solid obtained is dissolved under constant stirring the ethyl alcohol of 30 mL
In, the ethylenediamine of 1 mmol is then added dropwise, solution colour becomes lavender from light green color, and 3 h are stirred at room temperature, and solution is quiet
It sets, purple monocrystalline is obtained obtaining after a few days, filter, with a small amount of ethanol washing, air drying, yield 40% (in terms of nickel sulfate).[Ni
(en)3](L)2·3H2O, IR (KBr) cm-1: 3418 (w), 3288 (s), 3165 (s), 2925 (w), 2879 (w), 1599 (s),
1573 (s), 1461 (s), 1358 (s), 1266 (m), 1020 (s), 971 (s), 766 (s), 694 (s).Anal. Calcd. For
NiC26H42N8O7Se2(%): C, 39.26；H, 5.32；N, 14.09；Found (%): C, 39.19；H, 5.25；N, 14.10.[Ni
(en)3](L)·3H2O intramolecular, hydrone form 1 six-membered ring structure, the hexatomic ring by intermolecular and intramolecular hydrogen bond
Existing with chair conformation, the opposite side side of the hexatomic ring and diagonal equal, the side length on three side of hexatomic ring is respectively 0.275,
0.291 and 0.281nm, three angles of the hexatomic ring are respectively 87.617 °, 121.903 ° and 120.820 °.
Triazole thioether indole derivatives are synthesized by following route,
The synthetic method of compound 2 and compound 3 is the prior art.
The synthesis of compound 4: 5.0 g (21.0 mmol) compound 3 and 3.0 mL is added in 50 mL round-bottomed flasks
(63.0 mmol) 85% hydrazine hydrate (molar ratio 1:3) stands 48 h.After complete reaction, it filters, filter cake successively uses water, dichloro
Methane wash is dried in vacuo to obtain light yellow solid (compound 4).
Compound 5: it is anhydrous that 2.3 g (10.0 mmol) mL of compound 4 and 40.0 is added in the three-necked flask of 100 mL
Ethyl alcohol drips 10 mmol phenyl isothiocyanate of people after solid is completely dissolved, and flow back 3h, cooling, a large amount of white solids occurs
Object 5 is closed, filters, is washed with a small amount of deionized water, it is dry, obtain white solid.
The synthesis of compound 6: 3.6 g (10.0 mmol) compound 5 and 15.0 mL 2 is added in 50 mL round-bottomed flasks
Mol/L NaOH solution, flow back 4 h, adjusts pH value to neutrality with the hydrochloric acid solution of 4 mol/L, generates a large amount of yellow solid chemical combination
Object 6 filters, and washs, dry.
The synthesis of compound 7: in dry ampoule bottle, the stirrer of drying is added, 0.5 g is added under Ar gas shielded
Compound 6 (1.5mmol), 0.6 g potassium phosphate (2.9 mm01), 0.0077 g stannous chloride (0.073 mm01), 0.0088 g
1,1,1- trimethylolethane (0.073 mmol), bis- cyclopentadienyl of 2 mL DMF, 3 mmol 5- chloro-indole -2- ketone and 0.2mmol
Iron is uniformly mixed, reacts 24 h in 100 DEG C of oil bath under the protection of Ar gas.To after reaction, by ampoule bottle from oil
It is taken out in bath, it is cooling in room temperature.Solid is filtered out, rotary evaporation removes solvent, and target product is obtained after chromatography post separation.
Rhizoma Chuanxiong extracting solution is by the connected extraction kettle of sequence, separation reactor I, and separation reactor I I and storage tank are through supercritical CO2It mentions
It follows the example of obtained, includes the following steps,
Step 1 takes the Ligusticum chuanxiong Hort of a certain amount of crushing to put into extraction kettle, to extraction kettle, separation reactor I, separation reactor I I and storage
Hiding tank is respectively heated/cools down, and when extraction kettle temperature reaches 35 DEG C, the temperature of separation reactor I reaches 78 DEG C, the temperature of separation reactor I I
When spending 50 DEG C, CO is opened2Gas cylinder is filled with CO2Fluid；
Step 2, when the pressure of extraction kettle reaches 30MPa, the pressure of separation reactor I reaches 6MPa, and the pressure of separation reactor I I reaches
When to 8MPa, extraction, CO are started the cycle over2Flow is 12kg/h；
Step 3 merges the extract that separation reactor I and separation reactor I I discharge port respectively obtain to obtain palm fibre after extracting 1.5h
Yellow oil；
Step 4 takes Rhizoma Chuanxiong extracting solution, and being diluted to concentration by ethyl alcohol is 63%, and adjusting pH is 5.7, by volume 1:
0.08 n-trimethyl chitosan chloride is added into extracting solution, and 2 ~ 3h, filtering are stood after being sufficiently stirred at room temperature；
Step 5 takes filtrate, is that filtrate is by 100MPa by porosity under conditions of temperature is 50 DEG C in pressure
30%, the ceramic membrane filter that aperture is 10 μm.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (6)
1. a kind of eye syringe, it is characterised in that: including medicinal liquid cavity (1), fill collyrium, the medical fluid in the medicinal liquid cavity (1)
Chamber (1) bottom opening, medicinal liquid cavity (1) opening are fixedly connected with button cover top, and the button cover top opening, which is less than, buckles cover
Bottom opening, medicinal liquid cavity (1) opening are equipped with baffle (2), and the baffle (2) closes medicinal liquid cavity (1) opening；It is described
Button cover includes upper buckle cover and lower buckle cover, and the upper buckle cover and lower buckle cover are fabricated from a flexible material, the upper buckle
Cover and lower buckle cover are flexibly connected, and the lower buckle cover can be that rotation point is flipped outward with tie point, and button cover bottom is opened
Mouthful locate inclined face, button cover has most longwell and a most shortwall, the inclined surface and horizontal plane with 13 ° of angles, it is described on
Portion's button cover is identical as the wall length of lower buckle cover, and the upper buckle cover inner wall is fixedly connected two eye speculums (3), two eye speculum (3) phase
To being set on the inner wall of button cover most shortwall and most longwell, two eye speculum (3) is set to above tie point.
2. a kind of eye syringe as described in claim 1, it is characterised in that: the flexible material is made of silica gel, the flexibility
Material surface is covered with antibiotic layer, the antibiotic layer with a thickness of 300 μm, the antibiotic layer is grafted titanium dioxide by acrylate
Silicon is made.
3. a kind of eye syringe as claimed in claim 2, it is characterised in that: each eye speculum (3) is sheet, the eye speculum
(3) lower end has protrusion, and the height of the protrusion is 0.7mm, and the eye speculum (3) is by lower end to upper end gradually smoothly and in button cover
Wall connects.
4. a kind of eye syringe as claimed in claim 1 or 2, it is characterised in that: one end and medicinal liquid cavity (1) of the baffle (2)
Inner wall is fixedly connected, and the other end of the baffle (2) passes through medicinal liquid cavity (1) outer wall, extends to medicinal liquid cavity (1) outside, the baffle
(2) breakpoint is equipped with medicinal liquid cavity (1) inner wall connecting pin.
5. a kind of eye syringe as described in claim 1, it is characterised in that: the collyrium by 78 parts of physiological saline of mass parts,
26 parts of methylcellulose, 13 parts of Sodium Hyaluronates, 13 parts of taurines, 8 parts of triazole thioether indole derivatives, 5 parts of [Ni
(en)3](L)2·3H2O, 9 parts of Rhizoma Chuanxiong extracting solutions and 7 parts of preservative compositions, the structural formula of the triazole thioether indole derivatives
For。
6. a kind of eye syringe as described in claim 1, it is characterised in that: the collyrium passes through60Co- gamma Rays go out
Bacterium, radiation intensity 15kGy, radiation dose rate 3.6kGy/h.
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|---|---|---|---|
| CN201610827123.1A CN106214460B (en) | 2016-09-18 | 2016-09-18 | A kind of eye syringe |
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| CN106214460B true CN106214460B (en) | 2019-04-23 |
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| JP3096647U (en) * | 2003-03-24 | 2003-09-26 | 一枝 木村 | Disposable eyeball washer using dropper |
| CN101057860A (en) * | 2007-05-30 | 2007-10-24 | 杨文龙 | Eye drops and preparing method thereof |
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|---|---|---|---|---|
| CN202490163U (en) * | 2012-01-06 | 2012-10-17 | 刘琴 | Eye syringe |
| CN204542551U (en) * | 2015-03-24 | 2015-08-12 | 亓超逸 | A kind of adjustable medical eyedrops bottle support |
| CN205322768U (en) * | 2016-01-29 | 2016-06-22 | 张冬松 | Novel ophthalmology washs and uses medicine device |
| CN206391184U (en) * | 2016-09-18 | 2017-08-11 | 刘艳琳 | A kind of eye syringe |
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| Publication number | Publication date |
|---|---|
| CN106214460A (en) | 2016-12-14 |
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Effective date of registration: 20190321 Address after: 430061 No. 481 Zhongshan Road, Wuchang District, Wuhan City, Hubei Province Applicant after: WUHAN AIER EYE HOSPITAL CO., LTD. Address before: 610041 No. 1, 1-1 building, 180 Ju Lu Road, Wuhou District, Chengdu, Sichuan, 1 Applicant before: Chengdu Addison Biotechnology Co. Ltd. |
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