CN106213405A - A kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis and preparation method thereof - Google Patents
A kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis and preparation method thereof Download PDFInfo
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- CN106213405A CN106213405A CN201610608990.6A CN201610608990A CN106213405A CN 106213405 A CN106213405 A CN 106213405A CN 201610608990 A CN201610608990 A CN 201610608990A CN 106213405 A CN106213405 A CN 106213405A
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- 210000000582 semen Anatomy 0.000 title claims abstract description 35
- 206010003246 arthritis Diseases 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 230000003750 conditioning effect Effects 0.000 title claims abstract description 13
- 239000003814 drug Substances 0.000 claims abstract description 19
- 241000628997 Flos Species 0.000 claims abstract description 18
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 11
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 241000221635 Cladonia Species 0.000 claims abstract description 6
- 238000001035 drying Methods 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims abstract description 6
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Abstract
The invention discloses a kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis and preparation method thereof, by Radix Notoginseng powder, pollen, Semen Nelumbinis powder, Radix Rehmanniae Preparata, Radix Sanguisorbae, Radix Gentianae, Herba Ephedrae, Flos Carthami, Radix Tylophorae mollissimae, Herba Phyllanthi Urinariae, Semen Strychni, limacia sagittata, Herba Ophioglossi, Radix seu Folium Rubi Cochinchinensis, Herba Apocyni veneti, Rhizoma Alismatis, Herba Centellae, Cladonia alpestris (L.) Rabenh., Radix Polygoni Multiflori, Caulis Polygoni Multiflori, Flos Gomphrenae and Radix Ilicis Asprellae are prepared from, above-mentioned each Chinese medicine is decocted into medicinal liquid by proportioning mixing and water adding, it is subsequently adding Radix Notoginseng powder, pollen, Semen Nelumbinis powder, stir, it is evaporated to thick paste, drying under reduced pressure, it is ground into powder, be combined with flour or rice flour, make cookies, bread or steamed sponge cake.Chinese medicine is combined by the present invention with food, has not only played the dietary function of food, and has had treatment and the opsonic action having played Chinese medicine, and the present invention has good therapeutic effect to chronic arthritis, has no side effect, safely and effectively.
Description
Technical field
The present invention relates to field of food, a kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis and preparation method thereof.
Background technology
Chronic arthritis is a kind of disease that the middle-aging male caused by metabolism disorder and underexcretion is common
Sick.Multiple joint involvement seen from chronic arthritis, outbreak frequency, catabasis shortening, even after outbreak, pain is not alleviated.Along with me
State's growth in the living standard, dietary structure and living-pattern preservation, the increase of fat number, and owing to people move few,
Receptor site stimulation becomes again and injures joint, thus causes this disease sickness rate to increase the most rapidly, and sharp ache and recurrent exerbation, oneself becomes tired
Disturb big serious problems of patient with gout, not only had a strong impact on patient and the routine work of family members and life, and given society
Bring white elephant.
At present, modern medicine there is no radical cure method to this disease, and acute attack stage commonly uses anti-inflammatory agent and hormone therapy, but pain
Diarrhoea that wind patient often brings with kidney, cardiovascular, gastroenteropathy, and said medicine, gastrointestinal hemorrhage, cardiac muscle stalk
Extremely, injury of kidney etc. limit the use of Western medicine.Although, at present by the Chinese medicine of following treatment chronic arthritis, but this effect
Unsatisfactory, and human body is had certain side effect.
Summary of the invention
It is an object of the invention to provide a kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis and preparation method thereof, to solve
The problem proposed in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme:
A kind of Semen Nelumbinis powder alleviating conditioning chronic arthritis, is prepared from by the raw material of following weight portion: Radix Notoginseng powder 10～14 parts,
Pollen 12～16 parts, Semen Nelumbinis powder 20～24 parts, Radix Rehmanniae Preparata 12～14 parts, Radix Sanguisorbae 16～20 parts, Radix Gentianae 10～12 parts, Herba Ephedrae 8～
12 parts, Flos Carthami 16～20 parts, Radix Tylophorae mollissimae 13～15 parts, Herba Phyllanthi Urinariae 11～13 parts, Semen Strychni 9～11 parts, limacia sagittata 8～10 parts,
Herba Ophioglossi 6～8 parts, Radix seu Folium Rubi Cochinchinensis 6～8 parts, Herba Apocyni veneti 10～12 parts, Rhizoma Alismatis 14～16 parts, Herba Centellae 6～8 parts, Cladonia alpestris (L.) Rabenh. 11～
15 parts, Radix Polygoni Multiflori 10～14 parts, Caulis Polygoni Multiflori 12～16 parts, Flos Gomphrenae 4～6 parts, Radix Ilicis Asprellae 8～12 parts.
As the further scheme of the present invention: described pollen is in Pollen Pini, bee pollen, Flos Rosae Rugosas pollen, Flos Chrysanthemi powder
Kind.
The preparation method of a kind of described Semen Nelumbinis powder alleviating conditioning chronic arthritis, specifically comprises the following steps that
(1) being mixed by proportioning by above-mentioned each Chinese medicine, add each Chinese medicine gross weight 10～the deionized water of 12 times, first intense fire boils 5
～7min, then with slow fire boiling 2～3h, after filtration, add gross weight 8～the deionized water of 10 times, continue to decoct 1.5～
2.5h, filters, merges twice filtrate, be cooled to room temperature, standby；
(2) Radix Notoginseng powder, pollen, Semen Nelumbinis powder are sequentially added at normal temperatures in the filtrate of above-mentioned merging, stir while adding, extremely
It is sufficiently mixed uniformly, at 45～50 DEG C, carries out being evaporated to thick paste, drying under reduced pressure, be ground into powder；
(3) powder of preparation is mixed with Semen Nelumbinis powder,.
Compared with prior art, the invention has the beneficial effects as follows:
Chinese medicine is combined by the present invention with food, has not only played the dietary function of food, and have the treatment having played Chinese medicine with
And opsonic action, the present invention has good therapeutic effect, has no side effect, safely and effectively chronic arthritis.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, all
Belong to the scope of protection of the invention.
Embodiment 1
Alleviate the Semen Nelumbinis powder of conditioning chronic arthritis, the raw material of following weight portion be prepared from: Radix Notoginseng powder 10 parts, Pollen Pini 16
Part, Semen Nelumbinis powder 24 parts, 12 parts of Radix Rehmanniae Preparata, Radix Sanguisorbae 20 parts, Radix Gentianae 10 parts, 12 parts of Herba Ephedrae, 16 parts of Flos Carthami, Radix Tylophorae mollissimae 15 parts, Margarita
Grass 11 parts, Semen Strychni 11 parts, limacia sagittata 8 parts, Herba Ophioglossi 8 parts, Radix seu Folium Rubi Cochinchinensis 6 parts, Herba Apocyni veneti 12 parts, Rhizoma Alismatis 14 parts, Herba Centellae 8
Part, Cladonia alpestris (L.) Rabenh. 11 parts, Radix Polygoni Multiflori 14 parts, Caulis Polygoni Multiflori 12 parts, Flos Gomphrenae 6 parts, Radix Ilicis Asprellae 8 parts.
The preparation process of above-mentioned food is as follows:
(1) being mixed by proportioning by above-mentioned each Chinese medicine, add the deionized water of each Chinese medicine gross weight 10 times, first intense fire boils 5min,
Use slow fire boiling 2h again, after filtration, add the deionized water of gross weight 8 times, continue to decoct 1.5h, filter, merge twice mistake
Filtrate, is cooled to room temperature, standby；
(2) Radix Notoginseng powder, pollen, Semen Nelumbinis powder are sequentially added at normal temperatures in the filtrate of above-mentioned merging, stir while adding, extremely
It is sufficiently mixed uniformly, at 45 DEG C, carries out being evaporated to thick paste, drying under reduced pressure, be ground into powder；
(3) powder of preparation is mixed with Semen Nelumbinis powder,.
Embodiment 2
Alleviate the Semen Nelumbinis powder of conditioning chronic arthritis, the raw material of following weight portion be prepared from: Radix Notoginseng powder 12 parts, Flos Rosae Rugosas pollen
14 parts, Semen Nelumbinis powder 22 parts, 13 parts of Radix Rehmanniae Preparata, Radix Sanguisorbae 18 parts, Radix Gentianae 11 parts, 10 parts of Herba Ephedrae, 18 parts of Flos Carthami, Radix Tylophorae mollissimae 14 parts, precious
Pearl grass 12 parts, Semen Strychni 10 parts, limacia sagittata 9 parts, Herba Ophioglossi 7 parts, Radix seu Folium Rubi Cochinchinensis 7 parts, Herba Apocyni veneti 11 parts, Rhizoma Alismatis 15 parts, Herba Centellae 7
Part, Cladonia alpestris (L.) Rabenh. 13 parts, Radix Polygoni Multiflori 12 parts, Caulis Polygoni Multiflori 14 parts, Flos Gomphrenae 5 parts, Radix Ilicis Asprellae 10 parts.
The preparation process of above-mentioned food is as follows:
(1) being mixed by proportioning by above-mentioned each Chinese medicine, add the deionized water of each Chinese medicine gross weight 11 times, first intense fire boils 6min,
Use slow fire boiling 2.5h again, after filtration, add the deionized water of gross weight 9 times, continue to decoct 2h, filter, merge twice mistake
Filtrate, is cooled to room temperature, standby；
(2) Radix Notoginseng powder, pollen, Semen Nelumbinis powder are sequentially added at normal temperatures in the filtrate of above-mentioned merging, stir while adding, extremely
It is sufficiently mixed uniformly, at 47.5 DEG C, carries out being evaporated to thick paste, drying under reduced pressure, be ground into powder；
(3) powder of preparation is mixed with Semen Nelumbinis powder,.
Embodiment 3
Alleviate the Semen Nelumbinis powder of conditioning chronic arthritis, the raw material of following weight portion be prepared from: Radix Notoginseng powder 14 parts, pollen powder of chrysanthemun flower
12 parts, Semen Nelumbinis powder 20 parts, 14 parts of Radix Rehmanniae Preparata, Radix Sanguisorbae 16 parts, Radix Gentianae 12 parts, 8 parts of Herba Ephedrae, 20 parts of Flos Carthami, Radix Tylophorae mollissimae 13 parts, Margarita
Grass 13 parts, Semen Strychni 9 parts, limacia sagittata 10 parts, Herba Ophioglossi 6 parts, Radix seu Folium Rubi Cochinchinensis 8 parts, Herba Apocyni veneti 10 parts, Rhizoma Alismatis 16 parts, Herba Centellae 6
Part, Cladonia alpestris (L.) Rabenh. 15 parts, Radix Polygoni Multiflori 10 parts, Caulis Polygoni Multiflori 16 parts, Flos Gomphrenae 4 parts, Radix Ilicis Asprellae 12 parts.
The preparation process of above-mentioned food is as follows:
(1) being mixed by proportioning by above-mentioned each Chinese medicine, add the deionized water of each Chinese medicine gross weight 12 times, first intense fire boils 7min,
Use slow fire boiling 3h again, after filtration, add the deionized water of gross weight 10 times, continue to decoct 2.5h, filter, merge twice mistake
Filtrate, is cooled to room temperature, standby；
(2) Radix Notoginseng powder, pollen, Semen Nelumbinis powder are sequentially added at normal temperatures in the filtrate of above-mentioned merging, stir while adding, extremely
It is sufficiently mixed uniformly, at 50 DEG C, carries out being evaporated to thick paste, drying under reduced pressure, be ground into powder；
(3) powder of preparation is mixed with Semen Nelumbinis powder,.
Embodiment 4 clinical research is tested
One, clinical data
Choosing and connect subject patient with gout in August, 2015 in my institute 100 in January, 2013, this group all patients all meet
The gout diagnostic criteria that turbid damp addiction resistance type in " tcm syndrome diagnosis and treatment standard " implements diagnosis and Americanism damp disease association proposes, its
In have 55 male, 45 women, the mean age is (44.2 ± 1.1) year, and wherein 80 patient's courses of disease are within 3 years, 20
Patient's course of disease is within 3-6；20 patients are acute gouty arthritis, and 80 patients show effect the catabasis for gout.
Two, Therapeutic Method
Bread prepared by the embodiment of the present invention 2, eats twice every day, continuous edible tri month.
Three, the standard of curative effect evaluation
According to the clinical symptom disappearance such as " tcm syndrome diagnosis and treatment standard " efficacy assessment standard, patient articular is hot, swollen, red, pain, joint
Chamber synovial bursa liquid microscopy display aciculiform urate crystal disappears, and blood uric acid recovers normal level for curing；Patient articular's heat,
The clinical symptoms such as swollen, red, pain have been alleviated, serum uric acid level reduce, local joint skin carcinoma is itched, desquamation symptom is eased into
Take a turn for the better;Patients symptomatic is not eased, and its blood uric acid is not the most reduced to not heal.
Four, statistical procedures
Carrying out statistical procedures by SPSS13.0 software, compare employing paired t-test with before and after group treatment, measurement data is with (x
± s) represent, P ＜ 0.05 represents that diversity is more obvious, has statistical significance.
Five, therapeutic outcome
1, clinical efficacy contrast, the results are shown in Table 1.
The clinical treatment outcome table of table 1 present invention
| Group | Number of cases | Cure | Take a turn for the better | Do not heal | Effective percentage (%) |
| Treatment group | 100 | 62 | 32 | 6 | 94 |
As shown in Table 1, the present invention has good therapeutic effect to the gouty arthritis state of an illness.
2, the serum Uric Acid Concentration before and after contrast patient treatment
Before treatment, patient serum Uric Acid Concentration average out to (653.124 ± 82.252) μm ol L-1, after treatment, patient's blood uric acid is dense
Degree average out to (406.612 ± 45.205) μm ol L-1, its diversity contrast, difference have statistical significance ((P ＜ 0.05),
The results are shown in Table 2
。
Embodiment 5: model case
1. Tan, male, 58 years old, first visit in June, 2016.Extremities joint swells and ache 3 years, left swelling and pain in knee, looks into the both hands many gouts of foot
Tuberosity, red and swollen hotness, tenderness is obvious, left knee joint redness hotness, and tenderness is obvious, and diagnosis suffers from gouty arthritis.Adhere to food
With the cookies three months of the embodiment of the present invention 1, extremity tuberosity redness substantially alleviates, relieving swelling and pain of joints, and walking freely, is checked every
All oneself index normally, can normally work.
2. Wu, female, 76 years old, retired employees, in May, 2016 was weak because of the whole body, and soreness of waist pain, right chronic foot pain carrys out undergraduate course outpatient service
Treatment, disease is seen the most weak, right chronic foot pain, and diagnosis suffers from gouty arthritis, adheres to the bread three of the edible embodiment of the present invention 2
Individual month, waist was the sourest, and lower limb the most bitterly, freely, be all down to normal range in walking by renal function and uric acid.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter
From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim
Change is included in the present invention.
Claims (3)
1. the Semen Nelumbinis powder alleviating conditioning chronic arthritis, it is characterised in that be prepared from by the raw material of following weight portion: three
Seven powder 10～14 parts, pollen 12～16 parts, Semen Nelumbinis powder 20～24 parts, Radix Rehmanniae Preparata 12～14 parts, Radix Sanguisorbae 16～20 parts, Radix Gentianae 10～
12 parts, Herba Ephedrae 8～12 parts, Flos Carthami 16～20 parts, Radix Tylophorae mollissimae 13～15 parts, Herba Phyllanthi Urinariae 11～13 parts, Semen Strychni 9～11 parts, blue or green
Fel Bovis seu Bubali 8～10 parts, Herba Ophioglossi 6～8 parts, Radix seu Folium Rubi Cochinchinensis 6～8 parts, Herba Apocyni veneti 10～12 parts, Rhizoma Alismatis 14～16 parts, Herba Centellae 6～8
Part, Cladonia alpestris (L.) Rabenh. 11～15 parts, Radix Polygoni Multiflori 10～14 parts, Caulis Polygoni Multiflori 12～16 parts, Flos Gomphrenae 4～6 parts, Radix Ilicis Asprellae 8～12 parts.
The Semen Nelumbinis powder alleviating conditioning chronic arthritis the most according to claim 1, it is characterised in that described pollen is Flos pini
One in powder, bee pollen, Flos Rosae Rugosas pollen, Flos Chrysanthemi powder.
3. the preparation method of the Semen Nelumbinis powder alleviating conditioning chronic arthritis as claimed in claim 1, it is characterised in that tool
Body step is as follows:
(1) being mixed by proportioning by above-mentioned each Chinese medicine, add each Chinese medicine gross weight 10～the deionized water of 12 times, first intense fire boils 5
～7min, then with slow fire boiling 2～3h, after filtration, add gross weight 8～the deionized water of 10 times, continue to decoct 1.5～
2.5h, filters, merges twice filtrate, be cooled to room temperature, standby；
(2) Radix Notoginseng powder, pollen are sequentially added at normal temperatures in the filtrate of above-mentioned merging, stir while adding, to the most mixed
Close uniformly, at 45～50 DEG C, carry out being evaporated to thick paste, drying under reduced pressure, be ground into powder；
(3) powder of preparation is mixed with Semen Nelumbinis powder,.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE102017125166A1 (en) * | 2017-10-26 | 2019-05-02 | Quansheng Li | Detumescence-ODYNOLYSE OINTMENT |
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| CN101757580A (en) * | 2008-11-26 | 2010-06-30 | 杨汝静 | Traditional Chinese medicine for treating chronic rheumatic arthritis |
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| CN103478539A (en) * | 2013-08-18 | 2014-01-01 | 青岛福加德面粉有限公司 | Traditional Chinese medicine flour and application thereof |
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| CN103800609A (en) * | 2012-11-13 | 2014-05-21 | 石树华 | Food therapy formula for treating gout |
| CN104352907A (en) * | 2014-11-07 | 2015-02-18 | 洪立新 | Traditional Chinese medicine composition for treating chronic gouty arthritis |
| CN104435994A (en) * | 2014-12-22 | 2015-03-25 | 蒋亚静 | Traditional Chinese medicine for treating hyperosteogeny arthritis and preparation method thereof |
| CN105362423A (en) * | 2015-12-04 | 2016-03-02 | 沈德旭 | Traditional Chinese medicine preparation for treating phlegm-damp stagnation type stomach cancer, method for preparing traditional Chinese medicine preparation and application thereof |
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|---|---|---|---|---|
| CN101757580A (en) * | 2008-11-26 | 2010-06-30 | 杨汝静 | Traditional Chinese medicine for treating chronic rheumatic arthritis |
| CN103800609A (en) * | 2012-11-13 | 2014-05-21 | 石树华 | Food therapy formula for treating gout |
| CN103191330A (en) * | 2013-04-16 | 2013-07-10 | 孔建 | Traditional Chinese medicine used for treating swelling of limbs of hemiplegic patient |
| CN103478539A (en) * | 2013-08-18 | 2014-01-01 | 青岛福加德面粉有限公司 | Traditional Chinese medicine flour and application thereof |
| CN103735763A (en) * | 2014-01-22 | 2014-04-23 | 刘庆辉 | Traditional Chinese medicine composition for treating hyperostosis and cold arthritis and preparation method thereof |
| CN104352907A (en) * | 2014-11-07 | 2015-02-18 | 洪立新 | Traditional Chinese medicine composition for treating chronic gouty arthritis |
| CN104435994A (en) * | 2014-12-22 | 2015-03-25 | 蒋亚静 | Traditional Chinese medicine for treating hyperosteogeny arthritis and preparation method thereof |
| CN105362423A (en) * | 2015-12-04 | 2016-03-02 | 沈德旭 | Traditional Chinese medicine preparation for treating phlegm-damp stagnation type stomach cancer, method for preparing traditional Chinese medicine preparation and application thereof |
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| DE102017125166A1 (en) * | 2017-10-26 | 2019-05-02 | Quansheng Li | Detumescence-ODYNOLYSE OINTMENT |
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Application publication date: 20161214 |