CN1061867C - Powder medicine for tumour - Google Patents

Abstract

The present invention relates to a powder medicine for eliminating tumor and alleviating toxicity for treating liver cancer. The powder medicine belongs to an aqueous agent prepared by proportioning the pure Chinese medicine materials of active compounds according to the synergy and decocting with water. The components of the active compounds comprise barbed skullcap herb, hairy knotweed herb, bistortae, herba lobeliae radicantis, oldenlandia, small centipeda herb, lesser hypericum, Tianzhuocai, greater selaginella, red peony root, Linlanzi, peach seed, safflower, rehmannia root, twotoothed achyranthes root, bupleurum, platycodon root, orange, angelica, Sichuan coptis root, Chinese wolfberry root-bark, Gentiana triflora pall., common prism tuber, zedoray rhizome, pangolin scale, oyster shell, turtle shell, Yuanwuban, chicken's gizzard-membrane, largehead atractylodes rhozome, hemlock parsley and licorice root.

Description

The tumour water preparation

The present invention relates to a kind of medicine tumour water preparation for the treatment of hepatocarcinoma, is the water preparation that forms with decocting system with the pure Chinese medicinal herbs of former medicine.

Hepatocarcinoma is the malignant tumor of primary liver cell and hepatic portal bile duct cell, also claims primary hepatocarcinoma.At present, no matter the medicine of treatment hepatocarcinoma is Western medicine, or Chinese medicine, and report is many, but its effect and unsatisfactory.

The objective of the invention is to: invent the pure preferably Chinese herbal medicine aqua medicine of a kind of treatment liver cancer efficacy tumour water preparation.

The present invention realizes its purpose like this: this Department of Pharmacy with the water preparation that decocting system forms, makes the compatibility dosage of per 445 grams of former medicine of this water preparation with the pure Chinese medicinal herbs of former medicine, in gram, for:

Herba Scutellariae Barbatae 8-12, a lotus 6-12, seven lotus 8-16,

Herba Lobeliae Chinensis 20-35, Herba Hedyotidis Diffusae 8-12, Herba Centipedae 8-12,

Herba Hyperici Japonici 8-16, the tall and erect dish 6-12 in field, Herba Selaginellae Doederleinii 8-12,

Radix Paeoniae Rubra 8-12, the blue sub-8-12 of woods, Semen Persicae 6-12,

Flos Carthami 6-14, Radix Rehmanniae 10-20, Radix Achyranthis Bidentatae 8-12,

Smoke 6-12, Radix Platycodonis 8-16, swan shell 6-12,

Radix Angelicae Sinensis 6-12, Rhizoma Coptidis 8-12, ground joint 8-12,

Three flower Radix Gentianae 6-16, rhizoma sparganic 6-12, Rhizoma Curcumae 8-12,

Squama Manis 26-35, left shell 20-40, last first 20-40,

The military plate 8-16 of unit, Endothelium Corneum Gigeriae Galli 25-35, Rhizoma Atractylodis Macrocephalae 20-40,

Rhizoma Chuanxiong 6-12, Radix Glycyrrhizae 8-14.

Further specified below in conjunction with embodiment, but be not limited only to this.

Embodiment one

1, the former medicine compatibility of medicine dosage (in gram).Be furnished with in the former medicine of per 445 grams:

6, seven lotuses 8 of 12, one lotuses of Herba Scutellariae Barbatae, Herba Lobeliae Chinensis 35,

Herba Hedyotidis Diffusae 8, Herba Centipedae 8, Herba Hyperici Japonici 16, the tall and erect dish 6 in field,

Herba Selaginellae Doederleinii 8, Radix Paeoniae Rubra 12, the blue son 8 of woods, Semen Persicae 12,

Flos Carthami 6, the Radix Rehmanniae 10, Radix Achyranthis Bidentatae 8, ground smokes 6,

Radix Platycodonis 16, swan shell 6, Radix Angelicae Sinensis 12, Rhizoma Coptidis 12,

Ground joint 8, three flower Radix Gentianae 16, rhizoma sparganic 6, Rhizoma Curcumae 8,

Squama Manis 35, left shell 40, last first 20, first military plate 8,

Endothelium Corneum Gigeriae Galli 35, the Rhizoma Atractylodis Macrocephalae 40, Rhizoma Chuanxiong 6, Radix Glycyrrhizae 8.

2, manufacture method of medicine.Above-mentioned pure Chinese medicinal herbs is pressed compatibility dosage metering, add 4000 milliliters in water (tap water, well water), low baking temperature decocts, and when decoction is 1000 milliliters, filters, and cools off, and is final drug, the capping of bottling then.Produce in enormous quantities, get final product in the expansion of dosage ratio.

3, drug use method is preserved and taboo.

Using method.Obey 1000 milliliters every day, divide clothes four times, four hours once, and each 250 milliliters, ten is a course of treatment, serve on four courses of treatment and imitate good.

Preserve.Medicine is stored in shady and cool exsiccant place.

Taboo.Period in a medicine, fasting Oryza glutinosa, beef, Cyprinus carpio, outstanding fish, Carnis Sus domestica, tobacco and wine, spicy food are avoided sexual life.

4, clinical trial result.To using this Drug therapy entirely from the whole nation 48 routine hepatocarcinoma, after four courses of treatment, through CT and B ultrasonic and laboratory examination, 41 examples of fully recovering, produce effects 3 examples, relatively poor 4 examples, total effective rate 91.6% through patient reflection, has no side effect to patient.

Embodiment two

1, the former medicine compatibility of medicine dosage (in gram).Pure Chinese medicinal herbs dosage in the former medicine of per 445 grams is:

10, seven lotuses 10 of 10, one lotuses of Herba Scutellariae Barbatae, Herba Lobeliae Chinensis 30,

Herba Hedyotidis Diffusae 10, Herba Centipedae 10, Herba Hyperici Japonici 10, the tall and erect dish 10 in field,

Herba Selaginellae Doederleinii 10, Radix Paeoniae Rubra 10, the blue son 10 of woods, Semen Persicae 10,

Flos Carthami 10, the Radix Rehmanniae 15, Radix Achyranthis Bidentatae 10, ground smokes 10,

Stalk 10 short of money, swan shell 10, Radix Angelicae Sinensis 10, Rhizoma Coptidis 10,

Ground joint 10, three flower Radix Gentianae 10, rhizoma sparganic 10, Rhizoma Curcumae 10,

Squama Manis 30, left shell 30, last first 30, first military plate 10,

Endothelium Corneum Gigeriae Galli 30, the Rhizoma Atractylodis Macrocephalae 30, Rhizoma Chuanxiong 10, Radix Glycyrrhizae 10.

2, manufacture method of medicine, preservation, using method and taboo are with example one.

3, clinical trial result.Through to 51 routine liver cancer treatments, after four courses of treatment, through CT and B ultrasonic and laboratory examination, 41 examples of fully recovering, produce effects 5 examples, relatively poor 5 examples, total effective rate 90.1%, patient's reflection has no side effect.

Embodiment three

1, the former medicine compatibility of medicine dosage (in gram), the pure Chinese medicinal herbs dosage in the former medicine of per 445 grams is:

12, seven lotuses 16 of 8, one lotuses of Herba Scutellariae Barbatae, Herba Lobeliae Chinensis 20,

Herba Hedyotidis Diffusae 12, Herba Centipedae 12, Herba Hyperici Japonici 8, the tall and erect dish 12 in field,

Herba Selaginellae Doederleinii 12, Radix Paeoniae Rubra 8, the blue son 12 of woods, Semen Persicae 6,

Flos Carthami 14, the Radix Rehmanniae 20, Radix Achyranthis Bidentatae 12, ground smokes 12,

Radix Platycodonis 8, swan shell 12, Radix Angelicae Sinensis 6, Rhizoma Coptidis 8,

Ground joint 12, three flower Radix Gentianae 6, rhizoma sparganic 12, Rhizoma Curcumae 12,

Squama Manis 26, left shell 20, last first 40, first military plate 16,

Endothelium Corneum Gigeriae Galli 25, the Rhizoma Atractylodis Macrocephalae 20, Rhizoma Chuanxiong 12, Radix Glycyrrhizae 14.

2, manufacture method of medicine, preservation, using method and taboo are with example one.

3, clinical trial result.Through to 50 routine liver cancer treatments, after four courses of treatment, through CT and B ultrasonic and laboratory examination, 42 examples of fully recovering, produce effects 4 examples, relatively poor 4 examples, total effective rate 93.8%, patient's reflection has no side effect.

Pharmacology and effect analysis.

Hepatocarcinoma is said by the traditional Chinese medical science, be by lump in the abdomen, gather, the liver rump, lump at the left hypochondrium, addiction Huang, mass formed by blood stasis, hypochondriac pain etc. carry out dialectical executing and control.The pathogenesis that gets to the bottom of sb.'s illness can be summarized as the evil poison of impression, stagnation of dampness due to deficiency of the spleen, qi depression to blood stasis, and on the deficient basis of healthy energy, inside and outside combined pathogens causes evil poison cohesion what liver, and sending out is hepatocarcinoma.Evil poison invasion and attack, eating and drinking without temperance, disorder of emotion all can cause hepatocarcinoma, though its diseased region is closely related with taste in liver, and the two is normal for interacting, reciprocal causation causes pathological change various.Stagnation of liver-QI is not relaxed, and catharsis is immoderate, and edema with the liver involved is taken advantage of spleen, and spleen fortune is obstructed, and wet poly-expectorant is given birth to, the what the liver pulse that stagnates, hepatocarcinoma.Simultaneously, spleen soil is restrained, and middle burnt gas is stopped up, and QI-blood circulation is not smooth, and qi depression to blood stasis also can be sent out and is primary disease, in addition, insufficiency of the spleen leading to overabundance of dampness, the damp stasis of blood is long-pending, with the passing of time heat-transformation, damp and hot combined pathogens, hot and suffocating liver and gall, gallbladder can turn to be yellow.After tangible piece forms,, hinder mechanism of qi more along with increasing gradually, disturbance in functioning of QI, water liquid stops gathering, and holds in the what abdomen, then becomes ascites.Pathogenic fire derived from stagnation of liver-QI or wet accumulate heat-transformation, the venation of all burning makes outside the blood oozing from the body openings or subcuta neous tissue arteries and veins, makes and causes epistaxis, sends out speckle, hematemesis, has blood in stool etc.The liver and the kidney have a common source, and the kidney usually involved in chronic disease causes the exhaustion of Liver and kidney essence and blood, is YIN failing to keep YANG well eventually, and outer take off dead of empty sun waited.Medication clinically needs flexible Application, and dialectical executing controlled, lotus, Herba Scutellariae Barbatae, the tall and erect dish in field, Herba Selaginellae Doederleinii heat-clearing and toxic substances removing in the former medicine of this medicine, and it is anticancer to invigorate blood circulation; Herba Hedyotidis Diffusae, Herba Hyperici Japonici, Herba Centipedae, Herba Lobeliae Chinensis, seven lotus heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, expelling wind and cold, the logical inducing diuresis to remove edema of stealing; Radix Paeoniae Rubra, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong blood stasis dispelling stimulate the menstrual flow, activating blood circulation, pain relieving, eliminating mass abdominal mass; Smoke dispersing the stagnated live-QI to relieve the stagnation of QI; Radix Rehmanniae clearing away heat and cooling blood; The Radix Achyranthis Bidentatae promoting blood circulation to remove blood stasis, it is descending to draw the stasis of blood; Swan shell, Radix Platycodonis leave the breast intake of food in the morning and vomitting in the evening, remove the chest and diaphragm feeling of fullness, and the band medicine is up; Rhizoma sparganic, Rhizoma Curcumae removing blood stasis, eliminating mass abdominal mass are gathered; Lin Lanzi, Rhizoma Coptidis eliminating fire and detoxication, relieving restlessness, clearing away heat-damp and promoting diuresis; Three flower Radix Gentianae heat clearing and damp drying, move back the fire of liver and gall, the jaundice eliminating pox; Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, dampness diuretic; The Endothelium Corneum Gigeriae Galli activating the spleen helps digestion, and removes liver cirrhosis, hepatosplenomegaly disappears; Ground joint, first military plate enrich blood yin nourishing, nourish heart, removing heat from blood moves back steaming; Hard masses softening and resolving such as left side shell, Shang Jia, Squama Manis remove hepatosplenomegaly, and suppressing the hyperactive liver and subsiding YANG removes lump in the abdomen, the mass in the abdomen of dispelling; Radix Glycyrrhizae invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription reduce toxicity.Therefore, each Chinese herbal medicine compatibility of last speed, it is strong to make this medicine have a heat-clearing and toxic substances removing, eliminating mass abdominal mass, jaundice eliminating subcutaneous ulcer power, detoxicating and fighting cancer is arranged, eliminate hepatoma, promoting tissue regeneration by removing blood stasis, blood stasis dispelling stimulates the menstrual flow, the effect of activating blood circulation, hepatocarcinoma there is significant curative effect, through above-mentioned treatment, cure 124 examples, cure rate average out to 83.2% to 149 routine hepatocarcinoma, produce effects 12 examples, total effective rate is more than 90%.Because the hepatocarcinoma state of an illness is changeable, can be serious in treatment according to ascites, general debility with deficiency of QI, dry mouth with bitter taste, pain in the hepatic region be the situation of change of play, yellowish fur etc. very, suitably is aided with the medicine that other are suited the medicine to the illness, and also can be aided with Western medicine, and dialectical executing controlled, and effect is better.

Claims (1)

1, a kind of medicine tumour water preparation for the treatment of hepatocarcinoma is the water preparation made from decocting with the pure Chinese medicinal herbs of former medicine, it is characterized in that: make the compatibility dosage of per 445 grams of former medicine of this water preparation, and in gram, for:

Herba Scutellariae Barbatae 8-12, a lotus 6-12, seven lotus 8-16,

Herba Lobeliae Chinensis 0-35, Herba Hedyotidis Diffusae 8-12, Herba Centipedae 8-12,

Herba Hyperici Japonici 8-16, the tall and erect dish 6-12 in field, Herba Selaginellae Doederleinii 8-12,

Radix Paeoniae Rubra 8-12, the blue sub-8-12 of woods, Semen Persicae 6-12,

Flos Carthami 6-14, Radix Rehmanniae 10-20, Radix Achyranthis Bidentatae 8-12,

Smoke 6-12, Radix Platycodonis 8-16, swan shell 6-12,

Radix Angelicae Sinensis 6-12, Rhizoma Coptidis 8-12, ground joint 8-12,

Three flower Radix Gentianae 6-16, rhizoma sparganic 6-12, Rhizoma Curcumae 8-12,

Squama Manis 26-35, left shell 20-40, last first 20-40,

The military plate 8-16 of unit, Endothelium Corneum Gigeriae Galli 25-35, Rhizoma Atractylodis Macrocephalae 20-40,

Rhizoma Chuanxiong 6-12, Radix Glycyrrhizae 8-14.