CN106178073A - A kind of bandage that can automatically point out wound inflammation - Google Patents
A kind of bandage that can automatically point out wound inflammation Download PDFInfo
- Publication number
- CN106178073A CN106178073A CN201610713255.1A CN201610713255A CN106178073A CN 106178073 A CN106178073 A CN 106178073A CN 201610713255 A CN201610713255 A CN 201610713255A CN 106178073 A CN106178073 A CN 106178073A
- Authority
- CN
- China
- Prior art keywords
- silkworm silk
- cocoon
- bandage
- gauze
- silkworm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/56—Wetness-indicators or colourants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Abstract
The present invention discloses a kind of bandage that can automatically point out wound inflammation, wherein: by following manufacturing process steps: open cocoon, select silkworm, wash cocoon, for the first time degumming, for the second time degumming, dry, break up, combing, be cut into sprayed biological fluorescent agent on short fibre, braiding, immersion, drying, yet another waterproof silkworm silk gauze, it is sliced into equivalent size the most respectively, the gauze of bioluminescence agent is had to stack the section of immersion and dip-coating, fluorescent agent face is harmonious with immersion, transparent rubberized fabric is overlying on top layer, makes bandage;The present invention has for wound repair, is difficult to breed bacteria, and when wound infection, can send the advantages such as fluorescence early warning in time.
Description
Technical field
The present invention relates to hygiene article sector, a kind of bandage that can automatically point out wound inflammation.
Background technology
Bandage, is conventional a kind of surgery article.Bandage is generally the adhesive plaster of strip, and centre is provided with medicine layer,
Be used to be attached to wound, have opposing bacteriological aftergrowth, prevent wound secondary damage, the effect of protection wound surface.General bandage
The time used is unsuitable long, uses it after for a long time, and the adhesive plaster of bandage outer layer is airtight, will make wound and wound circumference
Skin whitening, deliquescing causes the infection of the secondary of antibacterial to cause wound more to deteriorate.Due to some wounds, wound surface is relatively
Greatly, recovering relatively slow, the short time uses bandage to be difficult to reach preferable effect, changes the most frequently and causes cost to increase,
On the other hand, the most effectively helping wound healing, to reduce the use time of bandage, the research in terms of this is the fewest;And
The mode that tradition is bound up a wound, if wound infection also cannot be known the very first time.
Summary of the invention
In order to overcome the disadvantages mentioned above of prior art, it is an object of the invention to provide a kind of for wound repair, be difficult to grow
Endophytic bacteria, and when wound infection, the most luminous early warning of energy can point out the bandage of wound inflammation automatically.
The technical solution adopted for the present invention to solve the technical problems is: a kind of wound that can automatically point out wound inflammation
Patch, wherein: described manufacturing process steps is as follows:
1) opening cocoon: by Bombyx bombycis opening, opening is not more than 1/3rd of Bombyx bombycis;
2) selecting silkworm: remove Pupa bombycis, select inwall without the excremental Bombyx bombycis of silkworm, inwall speckles with the excremental Bombyx bombycis of silkworm and abandons;
3) wash cocoon: the cocoon wash clean pollutant will selected with clear water, dry standby;
4) degumming for the first time: put standby cocoon into high temperature distillation still, temperature is set to 100 DEG C ~ 140 DEG C, cocoon and the ratio of water
Mixing for 1:1 ~ 3, after steaming and decocting 1 ~ 4 hour, the sericin water that will obtain derives high temperature distillation still;
5) degumming for the second time: add the pure water being not less than 60 DEG C, washs cocoon 5 ~ 30 minutes, by the sericin washes clean on cocoon top layer
After, the sericin water obtained is derived high temperature distillation still;
6) dry: the cocoon of washes clean sericin is taken out from high temperature distillation still, put drier into and dry moisture;
7) break up: put the cocoon opening part of drying into devil, open cocoon and break up and become silkworm silk;
8) combing: the silkworm silk broken up is put in tidy on carding machine;
9) it is cut into short fibre: the silkworm silk after tidy is cut into the chopped fiber of 3 ~ 5cm;
10) braiding: chopped fiber is woven into yarn, is then made into cloth stand-by;
11) immersion: the silkworm silk gauze prepared by method, is dipped in nutritional solution 5 ~ 30 minutes;It is made fully to hang liquid;
12) it is cut into dimension size pieces of cloth after being dried by the silkworm silk gauze after immersion;
13) by 10) prepare silkworm silk gauze take some, one side dip-coating bioluminescence agent;Dip-coating is had bioluminescence agent again
Silkworm silk gauze in an aseptic environment, air-dries under 25 ~ 60 DEG C of ambient temperatures;After air-drying, it is cut into dimension size pieces of cloth.
14) by 12) 13) two steps prepare equivalent specifications size silkworm silk Gauze stacking pressing.
15) transparent rubberized fabric is overlying on 14) prepare pressing Gauze on, prepare a kind of automatic prompting wound inflammation wound
Patch.
As a further improvement on the present invention: use nonwoven water to weave cotton cloth technology or short staple spinning is weaved cotton cloth technology, by short fibre
Dimension is made into cloth and replaces above-mentioned steps 10).
As a further improvement on the present invention: the nutritional labeling of described nutritional solution is alligator oil, silkworm silk aminoacid or green grass or young crops
Bur extract.
As a further improvement on the present invention: prepare the nutritional labeling in described nutritional solution as follows with water proportioning: 1 ~ 20ml:
100ml。
As a further improvement on the present invention: described bioluminescence agent is fluorescent particle capsule;Described fluorescent particle
The composition of capsule is green fluorescent protein;Described green fluorescent protein, under meeting weakly alkaline environment, can send green fluorescence.
As a further improvement on the present invention: described bandage is had bioluminescence agent by transparent rubberized fabric, one side dip-coating successively
Silkworm silk gauze, immersed with nutritional solution silkworm silk paster form;Described transparent adhesive tape is furnished with waterproof layer and adhesive layer composition;Described
One side dip-coating have the silkworm silk silk cloth of bioluminescence agent be positioned at transparent rubberized fabric adhesive layer lower section by without sericin silkworm silk gauze with
Mark layer forms;The described silkworm silk paster immersed with nutritional solution is formed with nutritional solution by without sericin silkworm silk gauze;Described nothing
Sericin silkworm silk gauze is made by pure silk cellulosic material.
Compared with prior art, the invention has the beneficial effects as follows:
1) form owing to the section pure silk cellulose fiber of the present invention weaves, be difficult to breed bacteria, do not absorb water, wound face is used
It is to press principle hemostasis;
2) immersed with alligator oil, silkworm silk aminoacid or the nutritional solution of Princepia utilis extract in section, for wound repair, effectively to
Wound provides nutrition;
3) section is provided with bioluminescence agent, and when wound infection, pathogenic bacteria phagotrophy liquid reproductive status will will swash in alkalescence
Send out faintly acid bioluminescence agent luminescence early warning, automatically at prompting wound inflammation, in order to accurately tracing and positioning and process wound
Change bandage in time.
Detailed description of the invention
In conjunction with embodiment, the present invention is further described:
A kind of bandage that can automatically point out wound inflammation, wherein: described bandage is had life by transparent rubberized fabric, one side dip-coating successively
The silkworm silk gauze of thing fluorescent agent, silkworm silk paster immersed with nutritional solution form;Described one side dip-coating has the silkworm of bioluminescence agent
Si Sibu is positioned at the lower section of the adhesive layer of transparent rubberized fabric and is formed with mark layer by without sericin silkworm silk gauze;Described immersed with nutrition
The silkworm silk paster of liquid is formed with nutritional solution by without sericin silkworm silk gauze;The described gauze of silkworm silk without sericin is made by pure silk cellulosic material
Form.
Embodiment one: a kind of bandage that can automatically point out wound inflammation containing silkworm silk amino-acid nutrition liquid
A kind of processing technology of short silk fiber, wherein: described manufacturing process steps is as follows:
1) opening cocoon: by Bombyx bombycis opening, opening is not more than 1/3rd of Bombyx bombycis;
2) selecting silkworm: remove Pupa bombycis, select inwall without the excremental Bombyx bombycis of silkworm, inwall speckles with the excremental Bombyx bombycis of silkworm and abandons;Avoid
Pupa bombycis and the manure contamination sericin purity extracted;
3) cocoon is washed: the cocoon wash clean pollutant will selected with clear water, such as the dust in transporting, the pollutant in air and people
Hands opens the pollutant of hand when cocoon is selected silkworm, and dries standby, and drying can use craft or drier to dry;
4) degumming for the first time: put standby cocoon into high temperature distillation still, temperature is set to 120 DEG C, and cocoon is 1:1.5 with the ratio of water
Mixing, after steaming and decocting 2 hours, pours out high temperature distillation still by the sericin water obtained;Because sericin heat can be accelerated higher than 60 DEG C to melt,
Therefore the temperature of high temperature distillation still is set to 120 DEG C, sericin melting speed can be made to double, beneficially degumming;
5) degumming for the second time: add the pure water obtained after level Four filter pressure system filters of 60 DEG C, washed 30 minutes by cocoon, will
After the sericin washes clean on cocoon top layer, the sericin water obtained is poured out high temperature distillation still;Because after degumming for the first time, cocoon top layer is also
Having sericin residue, so avoiding degumming unclean, carrying out second time degumming, it is to avoid purity is had an impact by water quality, so
Using level Four filter pressure system that water is filtrated to get pure water, actual filter pressure system herein uses prior art means,
These means do not list this scope of patent protection in;Degumming for the second time can guarantee that does not leaves over sericin on the fibroin of Bombyx bombycis;
6) dry: the cocoon of washes clean sericin is taken out from high temperature distillation still, put drier into and dry moisture;
7) break up: put the cocoon opening part of drying into devil, open cocoon and break up and become silkworm silk;
8) combing: the silkworm silk broken up is put in tidy on carding machine;
9) it is cut into short fibre: the silkworm silk after tidy is cut into the chopped fiber of 4cm;
10) braiding: chopped fiber is woven into yarn, is then made into cloth stand-by;
11) immersion: the silkworm silk gauze prepared by method, is dipped in nutritional solution 5 ~ 30 minutes;It is made fully to hang liquid;
12) it is cut into dimension size pieces of cloth after being dried by the silkworm silk gauze after immersion;
13) by 10) prepare silkworm silk gauze take some, one side dip-coating bioluminescence agent;Dip-coating is had bioluminescence agent again
Silkworm silk gauze in an aseptic environment, air-dries under 25 ~ 60 DEG C of ambient temperatures;After air-drying, it is cut into dimension size pieces of cloth.
14) by 12) 13) two steps prepare equivalent specifications size silkworm silk Gauze stacking pressing.
15) transparent rubberized fabric is overlying on 14) prepare pressing Gauze on, prepare a kind of automatic prompting wound inflammation wound
Patch.Pressing Gauze is combined the step employing traditional handicraft making bandage with transparent rubberized fabric, and this step does not list the present invention's in
Protection domain.
Principle: green fluorescent protein is a kind of biomaterial, can play biomaterial fluorescent labeling effect, can with another kind
Its biomaterial sending fluorescence is promoted to combine, it is possible to send fluorescence.We can be according to the position of fluorescence with glimmering
The region that light sends, comes position and the quantity of labelling another kind biomaterial, is a kind of the most safest biomarker method.
The present invention apply in because wound infection is caused by bacteria breed, the wound of ordinary people can in acidity,
Ph value is general about 5, and once wound infection, this ph value will change, and even becomes alkalescence.Work as wound infection
, pH value rises, and touching dip-coating has the silkworm silk gauze of green fluorescent protein, will promote to meet the green fluorescent protein of alkali variable color
Send fluorescence, inform that infecting occurs at this in the wounded, need to process in time;And time common, when not occurring infecting, on silkworm silk paster
Nutritional solution play repair wound effect;The silkworm silk aminoacid of nutritional solution, for supporting skin composition, can protect Bombycis mori one as silkworm silk
Sample, the skin surface at us forms one layer of nutrition protecting film, our skin of maintenance;Owing to paster uses pure silk element system
Forming, pure silk element itself is not easy breed bacteria, does not absorbs water, wound is bigger when, will not absorb the blood of patient,
The excellent haemostatic effect of comparison can be played and keep chip drying not breed bacteria.This bandage is relatively large patient wound
When the haemostatic effect that plays and remind the function of infection site excellent.
Embodiment two: a kind of bandage that can automatically point out wound inflammation containing alligator oil nutritional solution
The present embodiment uses water to knit technology and chopped fiber is made into the step 10) in cloth alternative embodiment one;
Use alligator oil as the silkworm silk amino-acid nutrition liquid in nutrient composition alternative embodiment one;
Other steps are consistent with step in embodiment one.
Embodiment three: a kind of bandage that can automatically point out wound inflammation containing Princepia utilis nutritional solution
Use Princepia utilis as the silkworm silk amino-acid nutrition liquid in nutrient composition alternative embodiment one;
Other steps are consistent with step in embodiment one.
In sum, after those of ordinary skill in the art reads file of the present invention, according to technical scheme and
Technology design makes other various corresponding conversion scheme without creative mental work, belongs to the model that the present invention is protected
Enclose.
Claims (6)
1. the bandage that can automatically point out wound inflammation, it is characterised in that: described manufacturing process steps is as follows:
1) opening cocoon: by Bombyx bombycis opening, opening is not more than 1/3rd of Bombyx bombycis;
2) selecting silkworm: remove Pupa bombycis, select inwall without the excremental Bombyx bombycis of silkworm, inwall speckles with the excremental Bombyx bombycis of silkworm and abandons;
3) wash cocoon: the cocoon wash clean pollutant will selected with clear water, dry standby;
4) degumming for the first time: put standby cocoon into high temperature distillation still, temperature is set to 100 DEG C ~ 140 DEG C, cocoon and the ratio of water
Mixing for 1:1 ~ 3, after steaming and decocting 1 ~ 4 hour, the sericin water that will obtain derives high temperature distillation still;
5) degumming for the second time: add the pure water being not less than 60 DEG C, washs cocoon 5 ~ 30 minutes, by the sericin washes clean on cocoon top layer
After, the sericin water obtained is derived high temperature distillation still;
6) dry: the cocoon of washes clean sericin is taken out from high temperature distillation still, put drier into and dry moisture;
7) break up: put the cocoon opening part of drying into devil, open cocoon and break up and become silkworm silk;
8) combing: the silkworm silk broken up is put in tidy on carding machine;
9) it is cut into short fibre: the silkworm silk after tidy is cut into the chopped fiber of 3 ~ 5cm;
10) braiding: chopped fiber is woven into yarn, is then made into cloth stand-by;
11) immersion: the silkworm silk gauze prepared by method, is dipped in nutritional solution 5 ~ 30 minutes;It is made fully to hang liquid;
12) it is cut into dimension size pieces of cloth after being dried by the silkworm silk gauze after immersion;
13) by 10) prepare silkworm silk gauze take some, one side dip-coating bioluminescence agent;Dip-coating is had bioluminescence agent again
Silkworm silk gauze in an aseptic environment, air-dries under 25 ~ 60 DEG C of ambient temperatures;After air-drying, it is cut into dimension size pieces of cloth.
14) by 12) 13) two steps prepare equivalent specifications size silkworm silk Gauze stacking pressing.
15) transparent rubberized fabric is overlying on 14) prepare pressing Gauze on, prepare a kind of automatic prompting wound inflammation bandage.
2. it is applicable to a kind of bandage that can automatically point out wound inflammation described in claim 1, it is characterised in that: use nonwoven
Technology that water weaves cotton cloth technology or short staple spinning is weaved cotton cloth, is made into chopped fiber cloth and replaces above-mentioned steps 10).
A kind of bandage that can automatically point out wound inflammation the most according to claim 1 and 2, it is characterised in that: described
The nutritional labeling of nutritional solution is alligator oil, silkworm silk aminoacid or Princepia utilis extract.
A kind of bandage that can automatically point out wound inflammation the most according to claim 3, it is characterised in that: prepare described battalion
Nutritional labeling in nutrient solution is as follows with water proportioning: 1 ~ 20ml:100ml.
A kind of bandage that can automatically point out wound inflammation the most according to claim 1 and 2, it is characterised in that: described
Bioluminescence agent is fluorescent particle capsule;The composition of described fluorescent particle capsule is green fluorescent protein;Described green is glimmering
Photoprotein, under meeting weakly alkaline environment, can send green fluorescence.
6. the bandage that can automatically point out wound inflammation, it is characterised in that: a kind of wound that can automatically point out wound inflammation
Patch, wherein: described bandage is had the silkworm silk gauze of bioluminescence agent by transparent rubberized fabric, one side dip-coating, successively immersed with nutritional solution
Silkworm silk paster composition;Described transparent adhesive tape is furnished with waterproof layer and adhesive layer composition;Described one side dip-coating has bioluminescence agent
The lower section of the silkworm silk silk cloth adhesive layer that is positioned at transparent rubberized fabric formed with mark layer by without sericin silkworm silk gauze;Described immersed with
The silkworm silk paster of nutritional solution is formed with nutritional solution by without sericin silkworm silk gauze;The described gauze of silkworm silk without sericin is by pure silk cellulosic material
It is made.
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CN201610713255.1A CN106178073A (en) | 2016-08-24 | 2016-08-24 | A kind of bandage that can automatically point out wound inflammation |
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CN201610713255.1A CN106178073A (en) | 2016-08-24 | 2016-08-24 | A kind of bandage that can automatically point out wound inflammation |
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Family
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CN201610713255.1A Pending CN106178073A (en) | 2016-08-24 | 2016-08-24 | A kind of bandage that can automatically point out wound inflammation |
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CN108179481A (en) * | 2018-02-07 | 2018-06-19 | 苏州先蚕丝绸生物科技有限公司 | A kind of method of refining of natural colorful silk |
CN115287796A (en) * | 2022-02-18 | 2022-11-04 | 盐城工业职业技术学院 | Method for producing yarn by utilizing castor silkworm flat silk |
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CN115287796A (en) * | 2022-02-18 | 2022-11-04 | 盐城工业职业技术学院 | Method for producing yarn by utilizing castor silkworm flat silk |
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Effective date of registration: 20180929 Address after: 510000 Guangzhou, Guangdong province Huadu District, Xinhua Street, No. 1 Pine Garden Road, Yongda new town, Heng Fa commercial and residential 5, 602 rooms. Applicant after: Liu Yongjian Address before: 510000 X1301-A301, 106 East Feng Ze Road, Nansha District, Guangzhou, Guangdong. Applicant before: CHINA NATIONAL SILK BIOLOGICAL TECHNOLOGY CO.,LTD. |
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RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161207 |