CN106176819A - A kind of manufacture method of propolis ball - Google Patents

A kind of manufacture method of propolis ball Download PDF

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Publication number
CN106176819A
CN106176819A CN201610658166.1A CN201610658166A CN106176819A CN 106176819 A CN106176819 A CN 106176819A CN 201610658166 A CN201610658166 A CN 201610658166A CN 106176819 A CN106176819 A CN 106176819A
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CN
China
Prior art keywords
propolis
ball
wax
pure
solid pure
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
CN201610658166.1A
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Chinese (zh)
Inventor
金帅
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Zhejiang Jintong Biotechnology Co Ltd
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Zhejiang Jintong Biotechnology Co Ltd
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Priority to CN201610658166.1A priority Critical patent/CN106176819A/en
Publication of CN106176819A publication Critical patent/CN106176819A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The manufacture method of a kind of propolis ball, specifically comprises the following steps that and propolis raw material is extracted with 95% edible ethanol, obtains solid pure propolis, purity >=95% of solid pure propolis;Then solid pure propolis is inserted in the environment of 1 DEG C ~ 18 DEG C, freezing more than 24 hours;The solid pure propolis powder through freezing processing is broken to the fine powder of more than 100 mesh again;In the environment of below 5 DEG C, the pure propolis fine powder through pulverizing being sent into pellet press and carries out pill, make propolis ball, after propolis ball is made, pack sealing icebox is store temporarily.Propolis ball of the present invention is pure bee glue product, is made into ball by freezing and low temperature environment, then is encapsulated in wax pill, in propolis ball manufacturing process, it is not necessary to add other solvents or additive.

Description

A kind of manufacture method of propolis ball
Technical field
The present invention relates to the manufacture method of a kind of propolis ball.
Background technology
Propolis is the resin that Apis gathers from plant spore or trunk, is mixed into the secretions of palatine gland on it, wax gland A kind of colloidal solid thing with aromatic odor processed.It is that Apidae animal apis cerana etc. is repaired secreted by Nidus Vespae Yellowish-brown or the stickum of pitchy, be a kind of extremely rare natural resources, have the title of " purple gold ", include 20 big Class more than totally 300 plants nutritional labeling.In the composition of propolis, the most representational active substance is the Cortex querci dentatae in flavone compound CAPE in element, terpenoid and organic acid.Quercetin is the effective ingredient of a lot of Chinese crude drug, have widely physiology and Pharmacological action.Quercetin is also called rutin or rutin, has the effect of Citrin sample.Data shows, it is crown that Cortex querci dentatae have expansion Blood vessel, the reduction effect such as blood fat, anti-platelet aggregation, have synergism with aspirin.The endothelium under different conditions can be suppressed Cell release Endothelin, to reduce the tonicity of blood vessel, for preventing thromboembolism from providing foundation.For many years, clinic is mainly used in Capillary hemorrhage and secondary buck medicine.Except flavonoid beyond the region of objective existence, propolis also has fragrance volatile oil, alkene terpenoid Thing, organic acid, flavanol compound, alcohol, phenol, aldehyde, ketone, ester, ether compound, enzyme and inorganic salt etc., propolis is just as a sky Right " Drug Storage ", can be used for there is skin moistening granulation promoting, and effect of anti-inflammatory analgetic can treat gastric ulcer, oral ulcer, burn and scald, skin Splitting pain, the disease such as radioprotective.
Because propolis has special viscosity and to hot extremely sensitive, it is difficult to make the pure bee glue preparation that can directly take, Therefore at present the most at home and abroad propolis is the most only made liquor, capsule and tablets and other formulations and taken, but above-mentioned dosage form is producing In must mix solvent or other auxiliary agents of vast scale, make consumer swallow into a large amount of solvents while taking propolis or help Agent and additive, take in solvent because of a large amount of accumulations after taking for a long time or auxiliary agent bring bigger health risk.
Summary of the invention
Adding vast scale solvent or the deficiency of additive to overcome bee glue preparation in prior art to need, the present invention provides The manufacture method of a kind of pure propolis ball, can produce the health food containing propolis of pure propolis pill.
The manufacture method of a kind of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis, and the purity of solid pure propolis >= 95%;
Step (2), inserts in the environment of-1 DEG C ~-18 DEG C by the solid pure propolis after step (1) processes, freezing 24 hours Above;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C.
As preferably, in step (2), solid pure propolis is embedded in the environment of-5 DEG C, freezing more than 24 hours.
As preferably, also include step (7), the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing is stained with gold Powder, argentum powder or Vermilion powder add a cover the name of an article.
As preferably, in step (3), pulverizer is used to carry out crushing operation.
Propolis ball of the present invention is pure bee glue product, is made into ball by freezing and low temperature environment, then is encapsulated in wax pill In, in propolis ball manufacturing process, it is not necessary to add other solvents or additive.
The beneficial effects of the present invention is: propolis ball of the present invention is pure bee glue preparation, compared with other bee glue preparations, overcomes Bee glue preparation produces needs to add vast scale solvent or an additive technology difficult problem, it is to avoid takes propolis for a long time and tires out in a large number The health risk that long-pending absorption solvent or other auxiliary agents bring, meanwhile, carries use very convenient.
Detailed description of the invention
Below by detailed description of the invention, the present invention is described in further detail.
Embodiment one: the manufacture method of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis;
Step (2), inserts in the environment of-1 DEG C by the solid pure propolis after step (1) processes, freezing more than 24 hours;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C;
Step (7), is stained with bronze, argentum powder or Vermilion powder by the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing and adds a cover The name of an article.
Embodiment two: the manufacture method of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis;
Step (2), inserts in the environment of-5 DEG C by the solid pure propolis after step (1) processes, freezing more than 24 hours;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C;
Step (7), is stained with bronze, argentum powder or Vermilion powder by the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing and adds a cover The name of an article.
Embodiment three: the manufacture method of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis;
Step (2), inserts in the environment of-9 DEG C by the solid pure propolis after step (1) processes, freezing more than 24 hours;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C;
Step (7), is stained with bronze, argentum powder or Vermilion powder by the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing and adds a cover The name of an article.
Embodiment four: the manufacture method of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis;
Step (2), inserts in the environment of-13 DEG C by the solid pure propolis after step (1) processes, freezing more than 24 hours;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C;
Step (7), is stained with bronze, argentum powder or Vermilion powder by the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing and adds a cover The name of an article.
Embodiment five: the manufacture method of propolis ball, specifically comprises the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis;
Step (2), inserts in the environment of-18 DEG C by the solid pure propolis after step (1) processes, freezing more than 24 hours;
Step (3), is crushed to the fine powder of more than 100 mesh by the solid pure propolis through step (2) freezing processing by pulverizer;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C;
Step (7), is stained with bronze, argentum powder or Vermilion powder by the roasting heat on alcohol burner of the wax pill surface Cornu Bovis seu Bubali stamp after sealing and adds a cover The name of an article.
Propolis ball of the present invention is pure bee glue preparation, compared with other bee glue preparations, overcomes bee glue preparation production needs and adds Add vast scale solvent or an additive technology difficult problem, it is to avoid take propolis for a long time and accumulate absorption solvent or other auxiliary agents in a large number The health risk brought, meanwhile, carries use very convenient.

Claims (4)

1. the manufacture method of a propolis ball, it is characterised in that specifically comprise the following steps that
Step (1), extracts propolis raw material with 95% edible ethanol, obtains solid pure propolis, and the purity of solid pure propolis >= 95%;
Step (2), inserts in the environment of-1 DEG C ~-18 DEG C by the solid pure propolis after step (1) processes, freezing 24 hours Above;
Step (3), is broken to the fine powder of more than 100 mesh by the solid pure propolis powder through step (2) freezing processing;
Step (4), below 5 DEG C in the environment of, the pure propolis fine powder pulverized through step (3) is sent into pellet press system Ball, makes propolis ball, and after propolis ball is made, pack seals, and inserts less than 0 DEG C icebox and stores temporarily;
Step (5), will take out through the propolis ball that step (4) process, wraps paraffin paper, further according to different size to every propolis ball Granule number loads wax pill shell, builds wax pill shell;
Step (6), under the room temperature condition of 18 DEG C ~ 25 DEG C, carries out being stained with wax sealing, wax liquid by the above-mentioned wax pill shell equipped with propolis ball Temperature be maintained at 65 DEG C ~ 75 DEG C.
The manufacture method of a kind of propolis ball the most according to claim 1, it is characterised in that: in step (2), solid pure honeybee Glue is embedded in the environment of-5 DEG C, freezing more than 24 hours.
The manufacture method of a kind of propolis ball the most according to claim 2, it is characterised in that: also include step (7), by sealing After wax pill surface Cornu Bovis seu Bubali stamp roasting heat on alcohol burner be stained with bronze, argentum powder or Vermilion powder and add a cover the name of an article.
4. the manufacture method of a kind of propolis ball as described in one of claim 1 ~ 3, it is characterised in that: in step (3), use Pulverizer carries out crushing operation.
CN201610658166.1A 2016-08-12 2016-08-12 A kind of manufacture method of propolis ball Withdrawn CN106176819A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057477A (en) * 2020-09-30 2020-12-11 江苏江大源生态生物科技股份有限公司 Method for preparing propolis Chinese medicinal pill

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011419A (en) * 2007-02-06 2007-08-08 傅金龙 Bee glue preparation and its preparation method
CN101912111A (en) * 2010-07-19 2010-12-15 马建中 Method for preparing high-content propolis soft capsules
CN102018728A (en) * 2009-09-17 2011-04-20 北京久和开源营养科技有限公司 Propolis extraction process

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011419A (en) * 2007-02-06 2007-08-08 傅金龙 Bee glue preparation and its preparation method
CN102018728A (en) * 2009-09-17 2011-04-20 北京久和开源营养科技有限公司 Propolis extraction process
CN101912111A (en) * 2010-07-19 2010-12-15 马建中 Method for preparing high-content propolis soft capsules

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
沈学梅: "《中药制剂学》", 31 May 2006, 中国医药科技出版社 *
韦旭斌等: "《鹿产品珍方与药膳》", 31 August 2004, 吉林科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057477A (en) * 2020-09-30 2020-12-11 江苏江大源生态生物科技股份有限公司 Method for preparing propolis Chinese medicinal pill

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Application publication date: 20161207