CN106176746A - A kind of child's injecting narcotic - Google Patents
A kind of child's injecting narcotic Download PDFInfo
- Publication number
- CN106176746A CN106176746A CN201610539601.9A CN201610539601A CN106176746A CN 106176746 A CN106176746 A CN 106176746A CN 201610539601 A CN201610539601 A CN 201610539601A CN 106176746 A CN106176746 A CN 106176746A
- Authority
- CN
- China
- Prior art keywords
- component
- child
- injecting narcotic
- narcotic
- injecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a kind of child's injecting narcotic, comprising: component A:
Description
Technical field
The present invention relates to a kind of child's injecting narcotic.
Background technology
Anesthetics is requisite medicine in medical surgery, is generally divided into general anesthetic and local anesthetic, and complete
Body anesthetics deeply suppresses cerebral cortex, makes people's mind disappear.Tradition use general anesthetic by ether and fluorochemical,
But such medicine storage request is higher, and photodissociation, pyrolysis, poor stability easily occur, and deposits and there is impurity the most at once, impact anesthesia effect
Really, when using especially for child, cause Anesthetic safety accident.Therefore in the urgent need to developing the stable fiber crops that a kind of child uses
Liquor-saturated dose.
Summary of the invention
It is an object of the invention to provide one and deposit stable, free from admixture produces, use safe efficient, have no side effect
Child's injecting narcotic.
The technical scheme is that a kind of child's injecting narcotic, comprising:
Component A:,
In formula: R1 is the alkyl of 1-4 carbon atom;R2 is benzyl;R3 is the alkylcarboxyalkyl of most 8 carbon atoms;
Component B: polysorbate80;
Component C: etomidate;
Component D: mepivacaine;
Component E: lignocaine and WS-23 are by quality 2:1 eutectic mixture.
Described component A:B:C:D:E mass ratio=1.5:0.8:4:28:2.5.
Use this compound to prepare anesthetics, can avoid producing, store, transport in decompose and produce impurity, impact anesthesia
Safety, improves safety in utilization.
Detailed description of the invention
A kind of child's injecting narcotic, comprising:
Component A:,
In formula: R1 is the alkyl of 1-4 carbon atom;R2 is benzyl;R3 is the alkylcarboxyalkyl of most 8 carbon atoms;
Component B: polysorbate80;
Component C: etomidate;
Component D: mepivacaine;
Component E: lignocaine and WS-23 are by quality 2:1 eutectic mixture.
Described component A:B:C:D:E mass ratio=1.5:0.8:4:28:2.5.
Claims (2)
1. child's injecting narcotic, comprising:
Component A:,
In formula: R1 is the alkyl of 1-4 carbon atom;R2 is benzyl;R3 is the alkylcarboxyalkyl of most 8 carbon atoms;
Component B: polysorbate80;
Component C: etomidate;
Component D: mepivacaine;
Component E: lignocaine and WS-23 are by quality 2:1 eutectic mixture.
A kind of child's injecting narcotic the most according to claim 1, is characterized in that: described component A:B:C:D:E mass ratio=
1.5:0.8:4:28:2.5.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610539601.9A CN106176746A (en) | 2016-07-11 | 2016-07-11 | A kind of child's injecting narcotic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610539601.9A CN106176746A (en) | 2016-07-11 | 2016-07-11 | A kind of child's injecting narcotic |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106176746A true CN106176746A (en) | 2016-12-07 |
Family
ID=57473094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610539601.9A Pending CN106176746A (en) | 2016-07-11 | 2016-07-11 | A kind of child's injecting narcotic |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106176746A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101765582A (en) * | 2007-04-26 | 2010-06-30 | 奥斯拜客斯制药有限公司 | Deuterium-labelled ketamine |
US20100303718A1 (en) * | 2003-10-08 | 2010-12-02 | David Anderson | Stabilized Uncoated Particles of Reversed Liquid Crystalline Phase Materials |
CN104706587A (en) * | 2013-12-16 | 2015-06-17 | 天津迈迪瑞康生物医药科技有限公司 | Etomidate fat emulsion concentrated solution, preparation method and application thereof |
-
2016
- 2016-07-11 CN CN201610539601.9A patent/CN106176746A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100303718A1 (en) * | 2003-10-08 | 2010-12-02 | David Anderson | Stabilized Uncoated Particles of Reversed Liquid Crystalline Phase Materials |
CN101765582A (en) * | 2007-04-26 | 2010-06-30 | 奥斯拜客斯制药有限公司 | Deuterium-labelled ketamine |
CN104706587A (en) * | 2013-12-16 | 2015-06-17 | 天津迈迪瑞康生物医药科技有限公司 | Etomidate fat emulsion concentrated solution, preparation method and application thereof |
Non-Patent Citations (1)
Title |
---|
史新华 等: "利多卡因联合依托咪酯在老年人无痛胃镜中的应用", 《世界临床药物》 * |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161207 |
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WD01 | Invention patent application deemed withdrawn after publication |