CN106176569A - A kind of prevent haze weather to the compositions of skin damage and application thereof - Google Patents

A kind of prevent haze weather to the compositions of skin damage and application thereof Download PDF

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Publication number
CN106176569A
CN106176569A CN201610751140.1A CN201610751140A CN106176569A CN 106176569 A CN106176569 A CN 106176569A CN 201610751140 A CN201610751140 A CN 201610751140A CN 106176569 A CN106176569 A CN 106176569A
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extract
cosmetics
compositions
mixture
present
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邓劲松
彭文丽
吴思瑶
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Ou Biao (guangzhou) Cosmetics Co Ltd
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Ou Biao (guangzhou) Cosmetics Co Ltd
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Priority to CN201610751140.1A priority Critical patent/CN106176569A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses and a kind of prevent haze weather to the compositions of skin damage and application thereof.The compositions of the present invention comprises Thallus Laminariae (Thallus Eckloniae) extract 15 weight portion and Alteromonad tunning extract 15 weight portion.The compositions of the present invention, can effectively resist damage that the injury of human body skin, chelating heavy metal, remediating heavy metal cause by pollutant component in air, reduce free radical damage.

Description

A kind of prevent haze weather to the compositions of skin damage and application thereof
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of haze weather and to the compositions of skin damage and answer With.
Background technology
Along with Development of Urbanization and the acceleration of process of industrialization, paint, grilled coal stove, wood combustion, cigarette combustion, Vehicle exhaust, industrial waste gas, building building cement dirt, waste incineration, etc. massive discharge of pollutant, cause the dust in air, thin The pollutant such as bacterium, virus, heavy metal (including lead, chromium, cadmium etc.), sulfur dioxide, nitrogen oxides, Carcinogenic Polycyclic Aromatic Hydrocarbons seriously surpass Mark, they combine with fog, allow weather moment become the most gloomy, formation haze weather, the most in recent years, along with Air quality runs down, and the frequency that haze weather phenomenon occurs is more and more higher, under this weather, when people's trip or daily During Working Life, the molecule (referring mainly to the diameter granule less than or equal to 2.5 microns, i.e. PM2.5) in air will Adhering to the oil membrane layer of skin people have no and take precautions against when, invade pore, at this moment the pollutant in molecule will Destroy the protective barrier of skin.
Skin is the first line of defence of protection human body, after the protective barrier of skin is destroyed, then can occur a series of Problem to skin damage, sulfur dioxide and nitrogen oxides to skin infringement be mainly the oxidation of free radical, at skin The improper free-radical oxidation effect occurred in skin surface and Skin Cell can accelerate cell injury and aging.Particulate matter can block up Plug pore, affect the normal metabolism of skin, cause that the colour of skin is uneven, the discharge of hydropenia, sebum is obstructed and lead acnegenic go out Existing.On particulate matter, the heavy metal ion of attachment can cause the albuminous degeneration of skin, causes pigmentation.Microbes causes skin Be inflamed reaction, is most commonly that by bacterial bacterial dermatosis.And heavy metal ion and microorganism all can cause Skin allergy.
At present, anti-haze weather is the most considerably less to the cosmetics of skin damage, and some compatibility is complicated, high cost, some Technique manufacture is complicated, raw material obtains the most one-sided antagonism haze weather injury to skin being difficult to, having, in view of prior art The defect existed, we should find, and mechanism is clear, exact efficacy is comprehensive, is specifically designed to antagonism haze weather to skin damage Compositions.
Summary of the invention
The weak point that it is an object of the invention to overcome prior art to exist and provide a kind of prevention haze weather to skin The compositions of skin injury, said composition has chelating heavy metal, the damage preventing heavy metal from causing, the merit of minimizing free radical damage Energy.
Another object of the present invention is to provide a kind of cosmetics comprising above-mentioned composition and above-mentioned composition making up Application in product.
For achieving the above object, the technical scheme that the present invention takes is: a kind of prevent the haze weather group to skin damage Compound, it is characterised in that described compositions comprises Thallus Laminariae (Thallus Eckloniae) extract 1-5 weight portion and Alteromonad tunning extract 1- 5 weight portions.Alteromonad tunning extract contains alduronic acid (glucose and galacturonic acid), the metal sun of heavy metal Ion can be with 4, the negative charge reaction of 5-epoxy tetrahydrophthalic acid di-isooctyl functional acid, thus reach to chelate heavy metal Purpose.
Preferably, described compositions comprises Thallus Laminariae (Thallus Eckloniae) extract 2-3 weight portion and Alteromonad tunning extract 1-3 Weight portion.
Through test, inventor finds that the weight portion of Thallus Laminariae (Thallus Eckloniae) extract is less than 2 parts, Alteromonad tunning extract Weight portion less than 1 part time, chelating heavy metal, reduce free radical damage ability all can decline.And the weight of Thallus Laminariae (Thallus Eckloniae) extract Part is higher than 3 parts, and the weight portion of Alteromonad tunning extract is higher than 3 parts, and the product skinfeel worked it out is thick and heavy, glutinous greasy, And also can increase cost.It is advantageous to be 2-3 weight portion for Thallus Laminariae (Thallus Eckloniae) extract and Alteromonad tunning extract is 1-3 Weight portion.
Preferably, described Thallus Laminariae (Thallus Eckloniae) extract is wedge base Thallus Laminariae (Thallus Eckloniae) extract.Wedge base Thallus Laminariae (Thallus Eckloniae) extract is for have in Sargassum body The lipid cell membrane material of Stabilization-special lecithin, alpha oleic acid derivatives and vitamin are separated and are prepared from, There is the functions such as strengthening sebum barrier, anti-light aging, minimizing skin free radical damage.
Preferably, described wedge base Thallus Laminariae (Thallus Eckloniae) extract dispersant is polarity oils and fats, preferably octanoic acid/tricaprin 3 parts, Alteromonad tunning extract dispersant is butanediol 3 parts.
Preferably, the carrier of described compositions is emulsus elite, emulsion, cream.
Present invention also offers a kind of cosmetics comprising described compositions.Preferably, described cosmetics also comprise adjuvant.
Preferably, described accessory package is containing following components in parts by weight: polyacrylate cross linked polymer 0.2-0.4 part, second Edetate disodium 0.01-0.3 part, allantoin 0.1-0.3 part, glycerol 2-6 part, levan 2-6 part, cetearyl alcohol 0.5- 1 part, polydimethylsiloxane 5-8 part, caprylic/capric triglyceride 3-6 part, vitamin E 0.4-0.8 part, double (methylol) miaow Oxazolidinyl urea and 0.3 part of mixture, phenoxyethanol and the mixture of Sensiva SC50 of iodine propilolic alcohol butyl mephenesin Carbamate 0.25 part, polysorbate-60 0.8-1.2 part, PEG-60 Span60 0.6-1 part, Jojoba oil 2-6 part.
Above-mentioned caprylic/capric triglyceride can also be expressed as caprylic/capric triglyceride, its be by caprylic/capric and The high-purity oils and fats of glycerine esterification.
Preferably, described cosmetics use following steps to be prepared from:
(1) by polyacrylate cross linked polymer, disodiumedetate, allantoin, glycerol, levan add go from In sub-water, it is heated to 85 DEG C and extremely dissolves completely, obtain aqueous phase;
(2) by polysorbate-60, PEG-60 Span60, cetearyl alcohol, Jojoba oil, poly-two Methylsiloxane, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C and extremely dissolve completely, obtain oil phase;
(3) step (2) gained oil phase is added in step (1) gained aqueous phase, homogenizing 4 minutes, then it is incubated emulsifying 5 minutes, Stirring be cooled to 45 DEG C, add Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, Bis(hydroxymethyl)imidazolidinyl urea and The most described cosmetic of mixture mix homogeneously of mixture, phenoxyethanol and the Sensiva SC50 of iodine propilolic alcohol butyl mephenesin Carbamate Product.
Preferably, described accessory package is containing following components in parts by weight: polyacrylate cross linked polymer 0.2-0.4 part, second Edetate disodium 0.01-0.3 part, allantoin 0.1-0.3 part, glycerol 2-6 part, levan 2-6 part, cetearyl alcohol 1-2 Part, polydimethylsiloxane 5-8 part, caprylic/capric triglyceride 3-6 part, vitamin E 0.4-0.8 part, double (methylol) miaow Oxazolidinyl urea and 0.3 part of mixture, phenoxyethanol and the mixture of Sensiva SC50 of iodine propilolic alcohol butyl mephenesin Carbamate 0.25 part, xanthan gum 0.2-0.4 part, hydrolecithin 1-1.5 part, cetearyl glucoside 2-3 part, isononyl isononanoate 2- 6 parts, ring five polydimethylsiloxane 2-5 part, Dimethicone Crosspolymer 2-5 part.
Preferably, described cosmetics use following steps to be prepared from:
A () is by polyacrylate cross linked polymer, disodiumedetate, allantoin, glycerol, levan, xanthan gum Add in deionized water, be heated to 85 DEG C and extremely dissolve completely, obtain aqueous phase;
B () is by hydrolecithin, polysorbate-60, cetearyl alcohol, cetearyl glucoside, the different nonyl of different n-nonanoic acid Ester, ring five polydimethylsiloxane, Dimethicone Crosspolymer, caprylic/capric triglyceride, vitamin E heat To 85 DEG C to dissolving completely, obtain oil phase;
C step (2) gained oil phase is added in step (1) gained aqueous phase by (), homogenizing 4 minutes, insulation emulsifying 5 minutes, stirs Mix and be cooled to 45 DEG C, add Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, Bis(hydroxymethyl)imidazolidinyl urea and iodine The most described cosmetic of mixture mix homogeneously of mixture, phenoxyethanol and the Sensiva SC50 of propilolic alcohol butyl mephenesin Carbamate Product.
Present invention also offers the application in cosmetics of the described compositions.
The beneficial effects of the present invention is: the invention provides a kind of collocation simple, cost is reasonable, and raw material is easily obtained Being specifically designed to the antagonism haze weather compositions to skin damage, said composition has resists in air pollutant component to human body skin The injury of skin, has chelating heavy metal, the damage preventing heavy metal from causing, the function of minimizing free radical damage.The present invention is from mist The Injury Mechanism of skin is started with by haze weather, uses the counte-rplan of science, selects wedge base Thallus Laminariae (Thallus Eckloniae) extract and Alteromonad The compounding acquisition by a certain percentage of tunning extract has resists the pollutant component injury to human body skin in air, has chela Close heavy metal, the damage preventing heavy metal from causing, the compositions of minimizing free radical damage function.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of test zone on arm of the present invention;
Fig. 2 is filter analysis figure of the present invention;
Fig. 3 a is the electron microscope picture of arm a-quadrant of the present invention;
Fig. 3 b is the electron microscope picture in arm B region of the present invention;
Fig. 4 is the peroxidating situation map of sebum of the present invention.
Detailed description of the invention
For better illustrating the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiments and the drawings pair The present invention is described further.
In embodiment, PLUS is Bis(hydroxymethyl)imidazolidinyl urea and the mixture of iodine propilolic alcohol butyl mephenesin Carbamate;PE- 9010 is the mixture of phenoxyethanol and Sensiva SC50;ZEN is polyacrylate cross linked polymer.Alteromonad ferments Product extract is purchased from LUCASMEYER company, trade name EXO-P PRODUCT INFORMATION;Wedge base Thallus Laminariae (Thallus Eckloniae) is extracted Thing is purchased from BIOTECHMARINE company.
Embodiment 1
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 1 weight Part and Alteromonad tunning extract 1 weight portion.
Cosmetics described in the present embodiment, it is emulsion, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
(1) ZEN, disodiumedetate, allantoin, glycerol, levan are added in deionized water, be heated to 85 DEG C To dissolving completely, obtain aqueous phase;
(2) by polysorbate-60, PEG-60 Span60, cetearyl alcohol, Jojoba oil, poly-two Methylsiloxane, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C and extremely dissolve completely, obtain oil phase;
(3) just step (2) gained oil phase adds in step (1) gained aqueous phase 4 minutes, insulation emulsifying 5 minutes, stirring fall Temperature, to 45 DEG C, adds wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUS, PE-9010 mix homogeneously i.e. institute State cosmetics.
Embodiment 2
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 2 weight Part and Alteromonad tunning extract 2 weight portion.
Cosmetics described in the present embodiment, it is emulsion, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
(1) ZEN, disodiumedetate, allantoin, glycerol, levan are added in deionized water, be heated to 85 DEG C To dissolving completely, obtain aqueous phase;
(2) by polysorbate-60, PEG-60 Span60, cetearyl alcohol, Jojoba oil, poly-two Methylsiloxane, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C and extremely dissolve completely, obtain oil phase;
(3) step (2) gained oil phase is added homogenizing 4 minutes in step (1) gained aqueous phase, insulation emulsifying 5 minutes, stirring It is cooled to 45 DEG C, adds wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUS, PE-9010 mix homogeneously i.e. Described cosmetics.
Embodiment 3
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 5 weight Part and Alteromonad tunning extract 5 weight portion.
Cosmetics described in the present embodiment, it is emulsion, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
(1) ZEN, disodiumedetate, allantoin, glycerol, levan are added in deionized water, be heated to 85 DEG C To dissolving completely, obtain aqueous phase;
(2) by polysorbate-60, PEG-60 Span60, cetearyl alcohol, Jojoba oil, poly-two Methylsiloxane, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C and extremely dissolve completely, obtain oil phase;
(3) homogenizing 4 minutes during just step (2) gained oil phase adds step (1) gained aqueous phase, insulation emulsifying 5 minutes, stir Mix and be cooled to 45 DEG C, add wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUS, PE-9010 mix homogeneously The most described cosmetics.
Embodiment 4
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 3 weight Part and Alteromonad tunning extract 3 weight portion.
Cosmetics described in the present embodiment, it is cream, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
A ZEN, disodiumedetate, allantoin, glycerol, levan, xanthan gum are added in deionized water by (), add Heat to 85 DEG C, to dissolving completely, obtains aqueous phase;
B () is by hydrolecithin, polysorbate-60, cetearyl alcohol, cetearyl glucoside, the different nonyl of different n-nonanoic acid Ester, ring five polydimethylsiloxane, Dimethicone Crosspolymer, caprylic/capric triglyceride, vitamin E heat To 85 DEG C to dissolving completely, obtain oil phase;
C step (b) gained oil phase is added homogenizing 4 minutes in step (a) gained aqueous phase, insulation emulsifying 5 minutes, stirring by () It is cooled to 45 DEG C, adds wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUS, PE-9010 mix homogeneously i.e. Described cosmetics.
Embodiment 5
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 2 weight Part and Alteromonad tunning extract 2 weight portion.
Cosmetics described in the present embodiment, it is cream, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
A ZEN, disodiumedetate, allantoin, glycerol, levan, xanthan gum are added in deionized water by (), add Heat to 85 DEG C, to dissolving completely, obtains aqueous phase;
B () is by hydrolecithin, polysorbate-60, cetearyl alcohol, cetearyl glucoside, the different nonyl of different n-nonanoic acid Ester, ring five polydimethylsiloxane, Dimethicone Crosspolymer, caprylic/capric triglyceride, vitamin E heat To 85 DEG C to dissolving completely, obtain oil phase;
C step (b) gained oil phase is added homogenizing 4 minutes in step (a) gained aqueous phase, insulation emulsifying 5 minutes, stirring by () It is cooled to 45 DEG C, adds wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUS, PE-9010 mix homogeneously i.e. Described cosmetics.
Embodiment 6
Preventing the haze weather compositions to skin damage described in the present embodiment, it comprises wedge base Thallus Laminariae (Thallus Eckloniae) extract 4 weight Part and Alteromonad tunning extract 4 weight portion.
Cosmetics described in the present embodiment, it is cream, and the toiletry bag of the present embodiment is containing haze described in the present embodiment The weather compositions to skin damage, it also comprises the adjuvant of following parts by weight of component:
The preparation method of cosmetics described in the present embodiment is as follows:
A ZEN, disodiumedetate, allantoin, glycerol, levan, xanthan gum are added in deionized water by (), add Heat to 85 DEG C, to dissolving completely, obtains aqueous phase;
B () is by hydrolecithin, polysorbate-60, cetearyl alcohol, cetearyl glucoside, the different nonyl of different n-nonanoic acid Ester, ring five polydimethylsiloxane, Dimethicone Crosspolymer, caprylic/capric triglyceride, vitamin E heat To 85 DEG C to dissolving completely, obtain oil phase;
C step (b) gained oil phase is added homogenizing 4 minutes in step (a) gained aqueous phase, insulation emulsifying 5 minutes, stirring by () It is cooled to 45 DEG C, adds wedge base Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, PLUSPLUS, PE-9010 mixing all Even i.e. described cosmetics.
Embodiment 7
It is below that cosmetics of the present invention prevent the haze weather effect assessment embodiment to skin damage.
Prevent haze weather that the emulsion of skin damage is carried out clinical trial embodiment 2 offer.
One, PM2.5 protection reaction (anti-adsorption reaction)
On the arm in 18 volunteers (age 42-70 year), a-quadrant as shown in Figure 1 is smeared in embodiment 2 and is not added Add the emulsion (comparison emulsion) of the present composition, arm B region is smeared the emulsion (present invention breast provided in embodiment 2 Liquid), all massage 2 minutes to fully absorbing.After 15 minutes, PM2.5 is smeared in A, B region on the arm scribbling emulsion.PM2.5 Clean with water after arm stops 20 minutes, wipe with dry cotton after massage.Image is obtained, result such as Fig. 2 institute with filter Show.Figure it is seen that compared with the skin that unused PM2.5 processes, smear the arm B area skin of emulsion of the present invention not The amount of adhesion of particles is higher than the amount of the unattached microgranule of the arm a-quadrant skin that comparison emulsion is smeared.It is experimentally confirmed, is coated with Smear the mass percent of the unattached microgranule of emulsion of the present invention compared with the skin that unused PM2.5 processes, can reach 83%.After illustrating to smear emulsion of the present invention, skin has the ability of stronger opposing PM2.5 absorption.
Being tested the skin in A, B region by ultramicroscope, test result is as shown in Fig. 3 a, 3b.Can from Fig. 3 b To find out, the B area skin surface smearing emulsion described in embodiment 2 defines a tunic, can be obvious from arrow direction Find out that the a-quadrant skin contamination thing smearing comparison emulsion adsorbs more (Fig. 3 a), illustrate to use the change containing the present composition Cosmetic can reduce the skin absorption to PM2.5, and protection skin also reduces the injury polluting initiation.
Two, free radical damage measure of merit is reduced
By the emulsion provided in the most each for human body fibroblast personal embodiment 2 with embodiment 2 is not added this The emulsion of inventive composition is cultivated 24 hours.
Cell UVB after cultivating stimulates (induced radical), finally by the fluorescence pointer peroxidating situation to sebum Confirming, with cytometry, analysis result is as shown in Figure 4.From fig. 4, it can be seen that the cell phase stimulated with unused UVB Ratio, smears the peroxide rate of sebum of comparison emulsion more than the sebum peroxide rate smearing emulsion of the present invention.Explanation is smeared Emulsion containing the present composition can protect skin the damage preventing skin from being caused by free radical.
Three, chelating heavy metal measure of merit
Heavy metal (lead cadmium, arsenic, hydrargyrum, nickel), due to its ionic charge, is high response metallic chemical element.They are the earth's crust Natural constituents, it is impossible to degrade or destroy.Chelatropic reaction is to neutralize heavy metal by ion binding (positive and negative charge attraction).
The compositions that the present invention provides has chelation to be because Alteromonad tunning extract to contain alduronic acid (glucose and galacturonic acid), the metal cation of heavy metal and 4,5-epoxy tetrahydrophthalic acid di-isooctyl functional acid Negative charge reaction.
The emulsion that will provide in embodiment 2, adds in the solution of the Cd ion containing 0.3 μ g/mL concentration and Pb ion, stirs Mix lower cultivation 3 hours.After 3 hours, measure the concentration of metal with atomic absorption spectrophotometry (FAAS), to investigate this Invent the chelate effect of described compositions.Measurement result shows, after 3 hours, the Cd ion in solution is 0.154 μ g/ by sequestration ML, the Pb ion in solution is 0.25 μ g/mL by sequestration.As can be seen here, the emulsion containing compositions of the present invention can neutralize Heavy metal, it is possible to reduce the PM2.5 toxicity to skin.
Four, antipollution consumer tests
57 volunteers (age 30-50 year) use the breast containing the present composition pollute that city (Guangzhou) lives Liquid, wherein, 29 is smoker, one day twice, uses 7 days, and using effect feedback is as shown in the table.
Positive accreditation 83%
Improve skin low and deep 82%
The outside invasion of opposing 82%
Moistening effect 80%
Shield effectiveness 79%
Antipollution effect 77%
Seem that skin is the most healthy 77%
Highlight skin 74%
Improve acclimatization change 73%
Pre-hypo-allergenic 70%
From upper table result, only use 7 days emulsions containing the present composition, have preferably feedback.
Last institute is it should be noted that, the present invention is only protected by above example in order to technical scheme to be described Protecting the restriction of scope, although being explained in detail the present invention with reference to preferred embodiment, those of ordinary skill in the art should Understand, technical scheme can be modified or equivalent, without deviating from the essence of technical solution of the present invention And scope.

Claims (10)

1. one kind is prevented the haze weather compositions to skin damage, it is characterised in that described compositions comprises Thallus Laminariae (Thallus Eckloniae) extract 1-5 weight portion and Alteromonad tunning extract 1-5 weight portion.
Compositions the most according to claim 1, it is characterised in that described compositions comprise Thallus Laminariae (Thallus Eckloniae) extract 2-3 weight portion and Alteromonad tunning extract 1-3 weight portion.
Compositions the most according to claim 1 and 2, it is characterised in that described Thallus Laminariae (Thallus Eckloniae) extract is wedge base Thallus Laminariae (Thallus Eckloniae) extract.
4. one kind comprises the cosmetics of compositions described in any one of claims 1 to 3.
Cosmetics the most according to claim 4, it is characterised in that described cosmetics also comprise adjuvant.
Cosmetics the most according to claim 5, it is characterised in that described accessory package is containing following components in parts by weight:
Polyacrylate cross linked polymer 0.2-0.4 part, disodiumedetate 0.01-0.3 part, allantoin 0.1-0.3 part, Glycerol 2-6 part, levan 2-6 part, cetearyl alcohol 0.5-1 part, polydimethylsiloxane 5-8 part, caprylic/capric triglyceride 3-6 part, vitamin E 0.4-0.8 part, Bis(hydroxymethyl)imidazolidinyl urea and the mixture of iodine propilolic alcohol butyl mephenesin Carbamate Mixture 0.2-0.6 part of 0.2-0.5 part, phenoxyethanol and Sensiva SC50, polysorbate-60 0.8-1.2 part, PEG-60 Span60 0.6-1 part, Jojoba oil 2-6 part.
Cosmetics the most according to claim 6, it is characterised in that described cosmetics use following steps to be prepared from:
(1) polyacrylate cross linked polymer, disodiumedetate, allantoin, glycerol, levan are added deionized water In, it is heated to 85 DEG C and extremely dissolves completely, obtain aqueous phase;
(2) by polysorbate-60, PEG-60 Span60, cetearyl alcohol, Jojoba oil, poly dimethyl Siloxanes, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C and extremely dissolve completely, obtain oil phase;
(3) step (2) gained oil phase is added in step (1) gained aqueous phase, homogenizing 4 minutes, then it is incubated emulsifying 5 minutes, stirring It is cooled to 45 DEG C, adds Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, Bis(hydroxymethyl)imidazolidinyl urea and iodine third The most described cosmetics of mixture mix homogeneously of mixture, phenoxyethanol and the Sensiva SC50 of alkynol butyl mephenesin Carbamate.
Cosmetics the most according to claim 5, it is characterised in that described accessory package is containing following components in parts by weight:
Polyacrylate cross linked polymer 0.2-0.4 part, disodiumedetate 0.01-0.3 part, allantoin 0.1-0.3 part, Glycerol 2-6 part, levan 2-6 part, cetearyl alcohol 1-2 part, polydimethylsiloxane 5-8 part, caprylic/capric triglyceride 3- 6 parts, vitamin E 0.4-0.8 part, Bis(hydroxymethyl)imidazolidinyl urea and the mixture 0.2-of iodine propilolic alcohol butyl mephenesin Carbamate Mixture 0.2-0.6 part of 0.5 part, phenoxyethanol and Sensiva SC50, xanthan gum 0.2-0.4 part, hydrolecithin 1-1.5 Part, cetearyl glucoside 2-3 part, isononyl isononanoate 2-6 part, ring five polydimethylsiloxane 2-5 part, poly dimethyl silicon Oxygen alkane cross linked polymer 2-5 part.
Cosmetics the most according to claim 8, it is characterised in that described cosmetics use following steps to be prepared from:
A polyacrylate cross linked polymer, disodiumedetate, allantoin, glycerol, levan, xanthan gum are added by () In deionized water, it is heated to 85 DEG C and extremely dissolves completely, obtain aqueous phase;
B () is by hydrolecithin, polysorbate-60, cetearyl alcohol, cetearyl glucoside, isononyl isononanoate, ring Five polydimethylsiloxane, Dimethicone Crosspolymer, caprylic/capric triglyceride, vitamin E are heated to 85 DEG C To dissolving completely, obtain oil phase;
C step (b) gained oil phase is added in step (a) gained aqueous phase by (), homogenizing 4 minutes, insulation emulsifying 5 minutes, stirring fall Temperature, to 45 DEG C, adds Thallus Laminariae (Thallus Eckloniae) extract, Alteromonad tunning extract, Bis(hydroxymethyl)imidazolidinyl urea and iodine propine The most described cosmetics of mixture mix homogeneously of mixture, phenoxyethanol and the Sensiva SC50 of alcohol butyl mephenesin Carbamate.
10. compositions application in cosmetics described in any one of claims 1 to 3.
CN201610751140.1A 2016-08-29 2016-08-29 A kind of prevent haze weather to the compositions of skin damage and application thereof Pending CN106176569A (en)

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CN106619477A (en) * 2016-12-23 2017-05-10 金日制药(中国)有限公司 Multipurpose isolating and moisturizing spray and preparation method thereof
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CN109431878A (en) * 2018-11-23 2019-03-08 广州市科能化妆品科研有限公司 A kind of anhydrous disposable gold seaweed makeup remover
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CN109953939A (en) * 2019-04-25 2019-07-02 美晨集团股份有限公司 A kind of natural moisture preserving composition and its application
CN115778861A (en) * 2022-12-15 2023-03-14 广州多多化妆品有限公司 Mousse blush suitable for sensitive muscle and preparation method thereof

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