CN106166225A - A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy - Google Patents

Abstract

The invention belongs to field of traditional Chinese, purpose is a kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy according to the traditional Chinese medical science, treatment type Ⅱdiabetes mellitus retinopathy being recognized mechanism and providing, each component of described Chinese medicine composition and mass parts ratio thereof are as follows: the Radix Astragali 150～320g, Radix Puerariae 80～180g, Radix Salviae Miltiorrhizae 80～180g, Radix Rehmanniae 100～300g, Radix Ophiopogonis herb 100～220g, Fructus Lycii 100～220g, Herba Portulacae 100～160g, Semen Cassiae 80～160g, Fructus Leonuri 60～90g, the Rhizoma Anemarrhenae 60～150g, Pollen Typhae 80～400g, quench one's thirst grass 180～680g, Hirudo 30～90g；The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy

Technical field

The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese drug-treated group treating type Ⅱdiabetes mellitus retinopathy Compound, particularly for the field of Chinese medicine composition of diabetic retinopathy.

Background technology

Diabetic retinopathy (DR) is most important performance in diabetic microangiopathy, is that one has spy The retinopathy that the opposite sex changes, is one of the Complicated with Severe card of diabetes.Clinically according to whether retinal neovascularization occurs For mark, the diabetic retinopathy not having retinal neovascularazation is referred to as non-proliferative diabetic retinal Pathological changes (NPDR) (or claiming simple type or background type), and the diabetic retinopathy having retinal neovascularazation is claimed (PDR) is become for proliferating diabetic retinopathy.

So, with regard to how finding a kind of Chinese medicine composition that can effectively treat type Ⅱdiabetes mellitus retinopathy, it is me Current problem in urgent need to solve.

Summary of the invention

Along with the development of China's Chinese medicine, on treatment type Ⅱdiabetes mellitus retinopathy, people are gradually The advantage appreciating Chinese traditional treatment type Ⅱdiabetes mellitus retinopathy, and good effect, instant effect, poison pair over the course for the treatment of Act on the advantages such as little, for the present situation of existing western medical treatment type Ⅱdiabetes mellitus retinopathy, it is an object of the invention to be There is provided a kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, to solve type Ⅱdiabetes mellitus retinopathy trouble The most restorative problem of person.This medicine is with common Chinese medicine as raw material, by selecting rational medicine and mass parts thereof Ratio, can effectively treat above-mentioned type Ⅱdiabetes mellitus retinopathy.

For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide one to treat type Ⅱdiabetes mellitus The Chinese medicine composition of property retinopathy, it is characterised in that each component of described Chinese medicine composition and its mass parts thereof are such as Shown in lower:

The Radix Astragali 150～320g, Radix Puerariae 80～180g, Radix Salviae Miltiorrhizae 80～180g, Radix Rehmanniae 100～300g, herb Radix Ophiopogonis 100～220g, Fructus Lycii 100～220g, Herba Portulacae 100～160g, Semen Cassiae 80～160g, Fructus Leonuri 60～90g, the Rhizoma Anemarrhenae 60～150g, Pu Huang 80～400g, quench one's thirst grass 180～680g, Hirudo 30～90g.

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described Chinese medicine composition Each component and its mass parts ratio as follows:

The Radix Astragali 170～280g, Radix Puerariae 90～160g, Radix Salviae Miltiorrhizae 90～160g, Radix Rehmanniae 115～260g, herb Radix Ophiopogonis 115～200g, Fructus Lycii 115～200g, Herba Portulacae 115～140g, Semen Cassiae 90～140g, Fructus Leonuri 70～80g, the Rhizoma Anemarrhenae 70～130g, Pu Huang 90～350g, quench one's thirst grass 200～600g, Hirudo 36～80g.

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described " preferred plan " Each component of Chinese medicine composition and its mass parts ratio as follows:

Radix Astragali 250g, Radix Puerariae 140g, Radix Salviae Miltiorrhizae 140g, Radix Rehmanniae 230g, herb 170g Radix Ophiopogonis, Fructus Lycii 170g, Herba Portulacae 120g, certainly Pine torch 120g, Fructus Leonuri 75g, Rhizoma Anemarrhenae 110g, Pollen Typhae 300g, quench one's thirst grass 510g, Hirudo 70g.

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described method include as Lower step is prepared from:

A, above-mentioned raw materials Chinese medicine is picked decontamination, dust and dried, be ground into superfine end according to mass parts ratio stand-by；

B, the method preparing Chinese kmedicine bolus agent according to tradition, after being sieved by ground superfine myrrh thing, put in medicine device and mix Mixing all, (granularity of its watered pill is: 4.7mm～4.8mm), and then dry, sealed packaging to be then prepared as watered pill.

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described instructions of taking is: By the watered pill medicine for preparing to take three times a day, the morning, noon and afternoon service once, and dosage 5g/time, warm water is sent after meal Clothes, 30 days are 1 course for the treatment of, and after 3～6 courses for the treatment of of taking medicine, hypoglycemic effect is notable, blood sugar recovery normal range.

Each raw material Chinese medicine in prescription of the present invention all has detailed in Chinese Pharmacopoeia, China's dictionary and its China's book on Chinese herbal medicine Record.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:

The Radix Astragali, nature and flavor: sweet, tepor, there is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation, be used for treating the deficiency of vital energy Weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty burst, burst for a long time do not hold back, Blood deficiency dull yellowish colored skin, interior-heat are quenched one's thirst, chronic nephritis proteinuria, diabetes；

Radix Puerariae, nature and flavor: sweet, pungent, flat, have expelling pathogenic factors from muscles for reducing heat, deliver examine, promoting the production of body fluid to quench thirst, effect of yang invigorating antidiarrheal, be used for controlling Treat fever caused by exogenous pathogens, rigidity pain on the head and nape, measles from the beginning of, rash go out smooth, epidemic febrile disease is thirsty, diabetes, have loose bowels, dysentery, hypertension, coronary disease Sick；

Radix Salviae Miltiorrhizae, nature and flavor: bitter, tepor, there is effect of blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving, be used for treating angina pectoris, the moon Through uncomfortable, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, lump in the abdomen, accumulation, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling；

Radix Rehmanniae, nature and flavor: sweet, cold, there is clearing away heat and cooling blood, yin nourishing, effect of promoting the production of body fluid, be used for treating in calentura crimson tongue excessive thirst, the deficiency of YIN Heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, are spitted blood, epistaxis, send out speckle dermexanthesis；

Radix Ophiopogonis herb, nature and flavor: hardship sweet, micro-, be slightly cold, there is YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, effect of blood sugar lowering, be used for treating sugar Urine disease, the cough of dryness of the lung dry cough, chronic consumptive disease, the insomnia thirsty, vexed of Tianjin wound, interior-heat are quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria；

Fructus Lycii, nature and flavor: sweet in the mouth, property are flat, have effect of nourishing the liver, nourishing kidney, lung moistening, be used for treating caused by liver and kidney deficiency, have a dizzy spell, Visual one clear, the expensive essence of soreness of the waist and knees, sexual impotence, cough due to consumptive disease, taking fluids profusely of quenching one's thirst；

Herba Portulacae, nature and flavor: sour, cold in nature, there is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, dehumidifying, treating stranguria effect, be used for treating pyretic toxicity and rush down Dysentery, pyretic stranguria, urine retention, leucorrhea with red and white discharge, metrorrhagia, hemorrhoidal bleeding, skin infection carbuncle furuncle, erysipelas, scrofula, exudative dermatitis, the disease such as the baldst；

Semen Cassiae, nature and flavor: salty hardship, Pingliang, nontoxic, there is effect of expelling wind and clearing away heat, detoxification and promoting urination, be used for treating anemopyretic cold, Influenza, acute conjunctivitis, jaundice due to damp-heat, acute and chronic nephritis, leukorrhagia, scrofula, carbuncle sore furuncle and phyma, mastitis；

Fructus Leonuri, nature and flavor: sweet in the mouth, pungent, cold nature, upper poison, there is effect of promoting blood flow to regulate menstruation, liver heat removing and eyesight improving, be used for treating menstruation The diseases such as uncomfortable, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, liver-heat headache, dizziness, conjunctival congestion and swelling pain, the raw cataracta of mesh；

The Rhizoma Anemarrhenae, nature and flavor: bitter in the mouth, cold in nature, there is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, effect of relieving restlessness of quenching the thirst, be used for treating epidemic febrile disease, High hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst；

Pollen Typhae, nature and flavor: sweet in the mouth, micro-pungent, property are put down, and have effect of hemostasis, blood stasis dispelling, diuresis, be used for treating haematemesis, spitting of blood, epistaxis, Standby dysentery, have blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, stasis of blood pain in puerperal, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, band Under, congenital deformity of the tongue, aphtha, ear, uncontrolled urination itch；

Quench one's thirst grass, nature and flavor: mildly bitter flavor, sweet, cool in nature flat, there is blood pressure lowering, heat-clearing and toxic substances removing, removing heat from blood promote the production of body fluid, the effect of diuresis of quenching one's thirst, For treat diabetes, hepatopathy, uremic, edema, hypertension, parotitis, suffer from abdominal pain, have a toothache, infections pain, skin ulcer of bursting, knife injury, flu are sent out Heat, laryngitis, tonsillitis, uric acid, neuralgia；

Hirudo, nature and flavor: salty hardship, flat, poisonous, there is removing blood stasis, removing blood stasis, effect of stimulating the menstrual flow, there is blood-retention, lump in the abdomen, accumulation, Fu Nvjing Close, the disease such as blood stasis becomes consumptive disease, injury from falling down, mesh also pain, nebula.

Medicine of the present invention is principle based on Chinese traditional treatment type Ⅱdiabetes mellitus retinopathy, from pharmacological action and work thereof Thinking by mechanism: with regard to type Ⅱdiabetes mellitus retinopathy, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, Above-mentioned disease there is good therapeutic effect.

Detailed description of the invention

The present invention is aiming at the treatment of above-mentioned type Ⅱdiabetes mellitus retinopathy and a kind of Chinese medicine formula of proposing, adopts The medicine effect prepared with this formula is good, and instant effect is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Under Face combines the detailed description of the invention of the present invention and is described in further detail:

Embodiment 1:

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described Chinese medicine composition each Individual component and its mass parts ratio thereof are as follows:

Radix Astragali 250g, Radix Puerariae 140g, Radix Salviae Miltiorrhizae 140g, Radix Rehmanniae 230g, herb 170g Radix Ophiopogonis, Fructus Lycii 170g, Herba Portulacae 120g, certainly Pine torch 120g, Fructus Leonuri 75g, Rhizoma Anemarrhenae 110g, Pollen Typhae 300g, quench one's thirst grass 510g, Hirudo 70g.

Embodiment 2:

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described Chinese medicine composition each Individual component and its mass parts ratio thereof are as follows:

Radix Astragali 280g, Radix Puerariae 160g, Radix Salviae Miltiorrhizae 160g, Radix Rehmanniae 260g, herb 200g Radix Ophiopogonis, Fructus Lycii 200g, Herba Portulacae 140g, certainly Pine torch 140g, Fructus Leonuri 80g, Rhizoma Anemarrhenae 130g, Pollen Typhae 350g, quench one's thirst grass 600g, Hirudo 80g.

Embodiment 3:

A kind of Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described Chinese medicine composition each Individual component and its mass parts ratio thereof are as follows:

Radix Astragali 320g, Radix Puerariae 180g, Radix Salviae Miltiorrhizae 180g, Radix Rehmanniae 300g, herb 220g Radix Ophiopogonis, Fructus Lycii 220g, Herba Portulacae 160g, certainly Pine torch 160g, Fructus Leonuri 90g, Rhizoma Anemarrhenae 150g, Pollen Typhae 400g, quench one's thirst grass 680g, Hirudo 90g.

Model case

Through clinical conditions diabetic retinopathy totally 940 example, the age is 485 examples of more than 58 years old, only Having 455 examples is less than 58 years old.921 examples effective in 940 example patients, 19 invalid examples, total effective rate reaches 98%.

Claims (3)

1. the Chinese medicine composition treating type Ⅱdiabetes mellitus retinopathy, it is characterised in that described Chinese medicine composition Each component and mass parts ratio thereof are as follows:

The Radix Astragali 150～320g, Radix Puerariae 80～180g, Radix Salviae Miltiorrhizae 80～180g, Radix Rehmanniae 100～300g, herb Radix Ophiopogonis 100～220g, Fructus Lycii 100～220g, Herba Portulacae 100～160g, Semen Cassiae 80～160g, Fructus Leonuri 60～90g, the Rhizoma Anemarrhenae 60～150g, Pu Huang 80～400g, quench one's thirst grass 180～680g, Hirudo 30～90g.

The Chinese medicine composition for the treatment of type Ⅱdiabetes mellitus retinopathy the most according to claim 1, it is characterised in that institute Each component and the mass parts ratio thereof of stating Chinese medicine composition are as follows:

The Radix Astragali 170～280g, Radix Puerariae 90～160g, Radix Salviae Miltiorrhizae 90～160g, Radix Rehmanniae 115～260g, herb Radix Ophiopogonis 115～200g, Fructus Lycii 115～200g, Herba Portulacae 115～140g, Semen Cassiae 90～140g, Fructus Leonuri 70～80g, the Rhizoma Anemarrhenae 70～130g, Pu Huang 90～350g, quench one's thirst grass 200～600g, Hirudo 36～80g.

3., according to the Chinese medicine composition of the treatment type Ⅱdiabetes mellitus retinopathy described in claim 1 to 2, its feature exists In, each component of described Chinese medicine composition and mass parts ratio thereof are as follows:

Radix Astragali 250g, Radix Puerariae 140g, Radix Salviae Miltiorrhizae 140g, Radix Rehmanniae 230g, herb 170g Radix Ophiopogonis, Fructus Lycii 170g, Herba Portulacae 120g, certainly Pine torch 120g, Fructus Leonuri 75g, Rhizoma Anemarrhenae 110g, Pollen Typhae 300g, quench one's thirst grass 510g, Hirudo 70g.