CN1061559C - Medicine for curing hystere myoma - Google Patents

Abstract

The present invention relates to a medicine for treating hysteromyoma, the ingredients of which comprise musk, saffron, pepperweed seed, scorpion, ground beetle, Chinese honeylocust abnormal fruit and leech. The medicine can control the development of hysteromyoma and have stable, favorable and obvious cure effect so as to achieve the purpose of thoroughly curing hysteromyoma.

Description

A kind of treatment hysteromyoma medicine

The present invention relates to a kind of medicine.

Hysteromyoma is that the uterus is carcinoid a kind of, forms by smooth muscle and connective tissue, and be one of modal benign tumor in the female sex organs, be mainly in the women of 30-50 between year.The traditional Chinese medical science thinks, the formation of this disease is how relevant with deficient qi and blood, the capable imbalance of blood.Common is qi depression to blood stasis, factors such as stagnation of phlegm-damp.Modern medicine thinks that the generation cause of disease of hysteromyoma it be unclear that, because this disease pilosity is born in the inharmonic women of maiden, widow and sexual life, helps most physicians to think, chronicity life imbalance, causing the pelvic cavity chronic congestion, is a major incentive of bringing out this disease.Hysteromyoma is commonly encountered disease, frequently-occurring disease, and is very harmful to women's physical and mental health, particularly to unmarried or child-bearing woman not, often causes dripping and produces or infertile.

The objective of the invention is: a kind of medicine for the treatment of hysteromyoma is provided,, strives for the thoroughly purpose of treatment by control tumor development, stable, improvement, produce effects.

Technical scheme of the present invention is: a kind of treatment hysteromyoma medicine, and its composition and part by weight are:

(1) Moschus 0.03--0.3 gram;

(2) Stigma Croci 6--7 gram;

(3) Semen Lepidii (Semen Descurainiae) 3--9 gram;

(4) Scorpio 3--6 gram;

(5) Eupolyphaga Seu Steleophaga 3--9 gram;

(6) Fructus Gleditsiae Abnormalis 3--6 gram;

(7) Hirudo 1.5--3 gram.

The pharmacological action of each composition is as follows among the present invention:

Moschus--the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain is used for carbuncle scrofula etc.

Stigma Croci--blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body is separated the stasis of blood and is calmed the nerves, and is used for menoxenia etc.

Semen Lepidii (Semen Descurainiae)--line water detumescence is used for that ascites pleural fluid is swollen, dysuria etc.

Scorpio--endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, scrofula, skin infection etc.

Eupolyphaga Seu Steleophaga--removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones, blood stasis amenorrhea, abdominal mass purplish or white patches on the skin mass in the abdomen etc.

Fructus Gleditsiae Abnormalis--mass dissipating and swelling eliminating, the pass key is obstructed, external treatment carbuncle etc.

Hirudo--removing blood stasis, removing blood stasis stimulates the menstrual flow, and is used for abdominal mass purplish or white patches on the skin mass in the abdomen, blood stasis amenorrhea etc.

Below by relevant laboratory report pharmacological action of the present invention is described:

The animal experiment report:

1. experiment material:

Medicine: slightly savory for pale brown color Chinese medicine coarse powder, concoct and provide by horizontal pool traditional Chinese medical science tumor clinic.

Cavia porcellus: body weight is 30 of female Cavia porcelluss between the 400--800 gram, by the breeding of Suzhou Medical College Experimental Animal Center and provide.

2 experimental techniques and result:

Imitative clinical application method, to (calculate about medicine 0.1 gram by kilogram/body weight, the 2--4 of suitable approximately people's usual amounts is doubly) be bonded into the ball shape with Lac regis apis, take up with silkworm silk, external one deck gauze wrapping back autoclave sterilization, then the Cavia porcellus four-footed is tightened, back of the body position is fixed on the plank and (is made vaginal orifice up), then under conditions for sterilization the disinfectant pill tremble with fear into the Cavia porcellus intravaginal, matched group is filled in isopyknic sterilized cotton ball, administration after 12 hours is taken off animal, the normal raising after 48 hours made vaginal smear, puts to death animal then, isolates vagina, uterus and cervix uteri send after with 10% formalin fixed Pathological Staff Room to make pathology section microscopy, and the result is as follows:

(1) clostridium tetani inspection: the vaginal smear before and after former medicine (non-sterile) and the administration is made antibacterial culturing through my microorganism teaching and research room of institute, and the result shows and all do not find clostridium tetani in former medicine and the vaginal smear.

(2) to local irritant effect: animal trembles with fear and disappears behind the pill that medicine makes, effectively obviously yellow-white secretions outflow in the vagina, it is thick and red and swollen to see fallopian tube during zootomy, vagina is also seen tangible irritation, find vagina during the pathological section microscopy, cervix uteri and Uterus wall hyperemia, and there is the neutrophil(e) cell to soak into, there are neutrophil and pus cell to ooze out in the vaginal canal, the minority animal still can be seen the vagina squamous epithelial cancer, cervix uteri, the inner membrance adenomatosis, phenomenons such as epithelium of cervix uteri hypersecretion, and control animals there is no significantly above reaction, in sum, the prompting medicine is to vagina, there is stimulation parts such as uterus and causes inflammation reaction.

The invention will be further described below in conjunction with embodiment:

Embodiment: a kind of treatment hysteromyoma medicine, its composition and part by weight are:

(1) Moschus 0.15 gram;

(2) Stigma Croci 6.5 grams;

(3) Semen Lepidii (Semen Descurainiae) 6 grams;

(4) Scorpio 4.5 grams;

(5) Eupolyphaga Seu Steleophaga 6 grams;

(6) Fructus Gleditsiae Abnormalis 4.5 grams;

(7) Hirudo 2 grams.

The present invention can make powder, also can make pill.

With relevant case report therapeutical effect of the present invention is described below:

The 100 routine clinical observations of treatment hysteromyoma:

One. clinical data:

1. case is originated: this group patient clarifies a diagnosis all through ultrasound diagnosis, classifies the clinical observation object as through screening again.

2. clinical observation object:

(1) loses surgical condition or the patient person that disagrees with the operative treatment.

(2) do not educate, older, the very big body constitution void of the muscular tumor person of declining.

(3) menorrhagia, thrombocytopenia, anemia, hypertension, heart disease etc. should not be accepted numb agent and operator.

3. this group case age reckling is 27 years old, the maximum 49 years old.

4. occupation: worker 51 people, cadre 27 people, peasant 15 people, teacher 6 people, other 1 people.

5. the course of disease: surplus the shortest person 3 months, elder 10 year.

6. symptom and sign: common menoxenia, menorrhagia, it is unclean to drench drop, few abdomen pain, low grade fever, anemia, malnutrition, the uterus increases, and the palace body touches lump, and ultrasound diagnosis can be found low echo area etc.

7. typing:

(1) qi stagnation and blood stasis type: inferior belly gas pain tenderness, metrorrhagia, the purple black piece that has of color, tongue fur is purple dark, and hesitant pulse is not smooth.

(2) liver qi stagnation type: costalgia is uncomfortable in chest, and few abdomen, distending pain of the breast, menses are more or less or to drench drop difficult clean, the yellowish stringy pulse of tongue fur.

(3) the heat in blood capable type of dying: flushing, xerostomia, thirst and desire for cold drink, dark red through the blood volume polychrome, tongue fur matter is red, full and rapid pulse.

(4) damp-heat accumulation type: it is vexed, thirsty to generate heat, through the stranguria with blood drop, and helvolus leukorrhagia, yellowish fur, soft and rapid pulse.

(5) insufficiency of spleen-qi type: complexion light is white, and is impractical, and distention and pain in the lower abdomen, anorexia be sugar just, and be many through blood volume, and color is light red or the pouring drop is unclean, and tongue is greasy in vain.

(6) kidney-Yang deficiency type: waist soreness, few abdomen cold, coldness of the body with chills, the continuous color of menses is clear or dark, and tongue fur turns white, thready and weak pulse.

8. Therapeutic Principle and method:

According to understanding and the Clinical typing of motherland's medical science to this disease, work out concrete Therapeutic Principle: liver-smoothing, qi-regulating is in harmonious proportion to dash and appoints promoting QI to circulate and dispersing the agglomeration of the pathogens, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, invigorate the spleen and warm the kidney, benefiting qi and nourishing blood etc.

Be 12 days basic courses of treatment first course of treatment, three months courses of treatment of treatment by Chinese herbs.

Second and third course of treatment, six to nine months for consolidating the course of treatment.

Two. determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs: distinguish according to Chinese medicine that differentiation of symptoms and signs for classification of syndrome such as picture of the tongue, pulse condition, symptom, Signs are executed and control, utilization the four methods of diagnosis and eight key links, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.Want emphasis to note on the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs: strong as patient body, muscular tumor is little, and therapeutic scheme should be attacked little benefit greatly, as muscular tumor and body mid rally strokes, reinforcement and elimination in combination.

Patient body is very weak, haemophilia, and basin blood, thrombocytopenia should be mended for a short time greatly and be attacked, and accomplish eliminating evilly just not hinder.

Three. the efficacy result analysis:

This group case is divided into produce effects, effective, invalid three kinds.

Produce effects: after treatment, cardinal symptom all disappears, clinical cure (B ultrasonic check tumor body disappears).

Effectively: muscular tumor reduces or dwindles, and symptom is the preceding improvement person of treatment.

Invalid: symptom does not disappear, muscular tumor and the preceding no significant change person of treatment.

Curative effect produce effects enabledisable add up to the symptom muscular tumor disappear 32 muscular tumors reduce or dwindle 27 metrorrhagias, 12 dysmenorrheas of leaking down to take a turn for the better take a turn for the better and 8 add up to 32 47 21 100

Find out from last table, after Most patients is received treatment, the special curative effect that all obtains at aspects such as menoxenia, dysmenorrheas in various degree.

Four. the course of treatment and efficacy result: curative effect produce effects enabledisable adds up to symptom to add up to 32 47 21 100 7 12 6 25 three courses of treatment above 5 10 4 19 of 20 25 11 56 second courses of treatment of first course of treatment

As seen, be the basic scheme of treatment first course of treatment, and curative effect is apparent in view, and also show better for consolidating curative effect second and third course of treatment.

Five. drug reaction:

Through clinical observation, see " doctor of Soviet Union animal test results " for details; Lab testing, to hepatic and renal function, blood defecation routine does not find that all the opposite sex changes.

Six. model case:

Yang Xiuhua: the woman, 33 years old, the worker of Sifang Rolling Stock Plant of the Ministry of Railways lived the Sifang District Xing Honglu of Qingdao City No. 35.At the beginning of 87 menstruation in advance and extremely, amount is many and to drench drop difficult clean, few abdomen pain continues nearly half a year, on March 8th, 87, through Qingdao Municipal Hospital and 5, Qingdao City hospitals for gynaecology and obstetrics ultrasound diagnosis in 87 on August, is diagnosed as multiple myomata.On August 21st, 87, hospitalization was after controlling a course of treatment, and it is normal that menstrual onset has become.87 years JIUYUE 100 hospitals of 3 Nikkei PLA and the B ultrasonic check of 26, Qingdao City hospitals for gynaecology and obstetrics of 87 on JIUYUE, muscular tumor reduces surplus one piece, and volume-diminished, after continue two courses of treatment of outpatient service after treatment again, Affiliated Hospital of Qingdao Medical Inst B ultrasonic check on March 8th, 88, hysteromyoma is complete obiteration, and original cervical erosion is fully recovered not recurrence more so far.

Li Aixian, the woman, 38 years old, the worker of Hohai University lived Suzhou, Nanjing road No. 16.In December, 88 is made forcep curettage in the Jiangsu Prov. People's Hospital pregnant eventually, and hysteromyoma is found in ultrasound diagnosis.May 17 was diagnosed as hysteromyoma in the ultrasound diagnosis of the attached First Academy of Nanjing Medical College again, and menoxenia at ordinary times fell behind 7--10 days.Hospitalization medication on July 22 in 89 year only five days, vagina is promptly discharged tissue substance, respectively at checking at Pingjiang District hospital, attached each the hospital's B ultrasonic of Nanjing Medical College on August 17th, 89 and on October 28th, 89, uterus and bilateral adnexa are all found obviously unusual, and menstruation is normal fully.

Claims (1)

1. treat the hysteromyoma medicine for one kind, it is characterized in that the part by weight of each composition is:

(1) Moschus 0.03-0.3 gram;

(2) Stigma Croci 6-7 gram;

(3) Semen Lepidii (Semen Descurainiae) 3-9 gram;

(4) Scorpio 3-6 gram;

(5) Eupolyphaga Seu Steleophaga 3-9 gram;

(6) Fructus Gleditsiae Abnormalis 3-6 gram;

(7) Hirudo 1.5-3 gram.