CN106138881A - A kind of Chinese medicine composition for treating pelvic inflammatory disease - Google Patents

A kind of Chinese medicine composition for treating pelvic inflammatory disease Download PDF

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Publication number
CN106138881A
CN106138881A CN201610626531.0A CN201610626531A CN106138881A CN 106138881 A CN106138881 A CN 106138881A CN 201610626531 A CN201610626531 A CN 201610626531A CN 106138881 A CN106138881 A CN 106138881A
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CN
China
Prior art keywords
radix
inflammatory disease
pelvic inflammatory
herba
chinese medicine
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CN201610626531.0A
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Chinese (zh)
Inventor
张晓甦
张艳
殷爱玲
许妍妍
孔德松
潘金津
刘思南
许玢
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Nanjing Hospital of TCM
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Nanjing Hospital of TCM
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Priority to CN201610626531.0A priority Critical patent/CN106138881A/en
Publication of CN106138881A publication Critical patent/CN106138881A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal

Abstract

The present invention discloses a kind of Chinese medicine composition for treating pelvic inflammatory disease, including following component: Flos Lonicerae, Herba Taraxaci, Radix Scutellariae, Radix Bupleuri, Radix Paeoniae Rubra, Cortex Moutan, Radix Salviae Miltiorrhizae, Caulis Sargentodoxae, Herba Patriniae, Semen Coicis and Herba Plantaginis.Prescription of the present invention can carry out heat-clearing and toxic substances removing for the disease of the pelvic inflammatory disease damp and hot folder stasis of blood, blood circulation promoting and blood stasis dispelling, hold concurrently with eliminating damp-heat, circulation of qi promoting is lifted altogether, evil except then sick from disappearing, few side effects high for the more existing similar drugs therapeutic efficiency of case in various degree, this formula can be brewed into Chinese patent medicine soup, and encapsulate preservation, taking convenience.

Description

A kind of Chinese medicine composition for treating pelvic inflammatory disease
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for treating pelvic inflammatory disease.
Background technology
Pelvic inflammatory disease be pathogen by the blood vessel of reproductive tract, lymphatic vessel or direct extension, cause inflammatory diseases of female genital tract very General name to empyema.What puerperal or infection post-abortion, the operation of intrauterine surgical, menstrual hygiene difference and adjacent organs infected spreads Being all the main cause that occurs of pelvic inflammatory disease, clinic mainly shows as lower abdominal pain, heating, vaginal secretions increase, and suffers from abdominal pain as continuing Property, movable or sexual intercourse postemphasis.Sick position at pelvic cavity, pathogenesis mainly blame for damp and hot knot of fighting, accompany blood stasis.Operation technique or health The unclean pelvic infection that causes, damp invasion of lower energizer, damp and hot knot of fighting, block QI-blood circulation for a long time, gas is capable does not freely then cause the stagnation of QI, and the stagnation of QI hinders Blood operation, forms the stasis of blood for a long time.Clinical treatment pelvic inflammatory disease, uses western medicine primary disease, and during medication, the state of an illness has and taken a turn for the better, drug withdrawal Rear easily recurrence, and side effect is bigger, it is impossible to thoroughly cure patient;Existing Chinese medicine class existing for property of Drug therapy is the highest, treatment Imitating inconspicuous, the problem such as take effect slow.
Summary of the invention
Goal of the invention: the object of the invention provides the Chinese medicine for treating pelvic inflammatory disease that a kind of specific aim is high, therapeutic effect is good Compositions.
Technical scheme: a kind of Chinese medicine composition for treating pelvic inflammatory disease of the present invention, including following component: gold silver Flower, Herba Taraxaci, Radix Scutellariae, Radix Bupleuri, Radix Paeoniae Rubra, Cortex Moutan, Radix Salviae Miltiorrhizae, Caulis Sargentodoxae, Herba Patriniae, Semen Coicis and Herba Plantaginis.
Further, the described Chinese medicine composition for treating pelvic inflammatory disease, including following component: Flos Lonicerae 10-15g, Pu Herba Taraxaci 10-15g, Radix Scutellariae 10-15g, Radix Bupleuri 10-15g, Radix Paeoniae Rubra 10-15g, Cortex Moutan 10-15g, Radix Salviae Miltiorrhizae 10-15g, Caulis Sargentodoxae 10-15g, Herba Patriniae 10-15g, Semen Coicis 10-15g and Herba Plantaginis 10-15g.
Further, following component is included described in: Flos Lonicerae 12g, Herba Taraxaci 13g, Radix Scutellariae 12g, Radix Bupleuri 11g, Radix Paeoniae Rubra 14g, Cortex Moutan 14g, Radix Salviae Miltiorrhizae 10g, Caulis Sargentodoxae 11g, Herba Patriniae 15g, Semen Coicis 14g and Herba Plantaginis 12g.
The Chinese medicine composition of the treatment pelvic inflammatory disease that the present invention provides can be applicable to treat the Chinese medicine composition of pelvic inflammatory disease, is used for In the medicine of preparation treatment pelvic inflammatory disease.
Beneficial effect: prescription of the present invention can carry out heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling for the disease of the pelvic inflammatory disease damp and hot folder stasis of blood, holds concurrently With eliminating damp-heat, circulation of qi promoting is lifted altogether, evil except then sick from disappearing, high for the more existing similar drugs therapeutic efficiency of case in various degree, Few side effects, this formula can be brewed into Chinese patent medicine soup, and encapsulate preservation, taking convenience.
Detailed description of the invention
Below by embodiment, technical solution of the present invention is described in detail, but protection scope of the present invention is not limited to In described embodiment.
Embodiment: a kind of Chinese medicine composition for treating pelvic inflammatory disease, including following component: Flos Lonicerae 12g, Herba Taraxaci 13g, Radix Scutellariae 12g, Radix Bupleuri 11g, Radix Paeoniae Rubra 14g, Cortex Moutan 14g, Radix Salviae Miltiorrhizae 10g, Caulis Sargentodoxae 11g, Herba Patriniae 15g, Semen Coicis 14g and Herba Plantaginis Grass 12g.
Flos Lonicerae, Herba Taraxaci heat-clearing and toxic substances removing in side, wherein Herba Taraxaci again can be with dispersing swelling and dissipating binds;Caulis Sargentodoxae, Herba Patriniae heat clearing away solution Poison, dispersing swelling and dissipating binds, stasis-dispelling and pain-killing, strengthen the power of heat clearing away;Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication;Semen Coicis, Herba Plantaginis dampness removing, make Damp and hot go from urine, damp and hot disappear, evil from removing;Radix Paeoniae Rubra, Cortex Moutan, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, the blood stasis then gas that disappears voluntarily, damp and hot has gone Outlet;Finally adding and use Radix Bupleuri depressed liver-energy dispersing and QI regulating, gas row then to promote damp and hot removal, blood stasis is dissipated;The each component drug added Effect is different, therefore, needs the ratio collocation of each component suitably for reaching preferable therapeutic effect, makes a general survey of full side, clearing away heat-damp and promoting diuresis, dispel The stasis of blood, circulation of qi promoting is lifted altogether, evil except then sick from disappearing.
The present invention is to be soaked 20-60 minute by above-mentioned prescription, and the water yield floods powder 3-5cm, and it is slow that rear slow fire is boiled in first big fire Enduring and cease fire to 200-250ml, filter off medicinal residues and drink treatment, instructions of taking is potion every day, at twice decoction being taken warmly, in conjunction with clinical manifestation And gynecologial examination result adjusts and treats the course for the treatment of.
The therapeutic effect using this Chinese medicine formula to carry out clinical treatment is divided into recovery from illness, effective, effective and invalid four classes, recovery from illness Referring to take in one menstrual cycle of this prescription, pelvic inflammation improves, and pelvic inflammation no longer recurs, multiple row gynecologial examination not and Abnormal;Effective referring to takes the 10-14 agent of this prescription, and pelvic inflammatory disease problem is obviously improved, and takes in a menstrual cycle, without substantially Pelvic inflammatory symptom, multiple row gynecologial examination is not and substantially abnormal;Effectively refer to take in the 10-14 agent of this prescription, pelvic inflammatory disease problem Making moderate progress, in two menstrual cycle, without obvious pelvic inflammatory symptom, multiple row gynecologial examination is not and substantially abnormal;Invalid refer to Take three menstrual cycle pelvic inflammatory disease problems continuously to be not improved.
For verifying this prescription curative effect to different age group patient and the safety of therapeutic process further, to 102 examples Out-patient's case carries out treatment track record, is randomly divided into treatment I group 52 example, compares I group 50 example;In treatment I group, the age 20-29 year 10 examples, 30-39 year 30 examples, 40-49 year 11 examples, more than 50 years old 1 example, 1 year person 22 example of course of disease <, 1-5 28 example, > 5 Year 2 examples.Comparison I group 50 example, age 20-29 year 9 examples, 30-39 year 31 examples, 40-49 year 9 examples, more than 50 years old 1 example;Course of disease < 1 year Person 19 example, 1-5 29 example, 5 years 2 examples of >.Two groups of data there was no significant difference (P > 0.05) through statistical procedures.Treatment I group is given This prescription is administered orally, and begins to take after menstruation, and first 3 days time-outs of menstrual phase are taken medicine, and take three menstrual cycle continuously;Comparison I group gives first Nitre azoles, health woman's inflammation capsule and BAOFUKANG SHUAN treatment.Observation index: 1. soreness of waist stomachache, rectal tenesmus and band after main detection treatment Under character;2. gynecologial examination thickens, tenderness, cervix uteri praise the symptoms such as pain, and concrete outcome is as shown in table 1.
The therapeutic effect synopsis of table 1 different age group patient
For verifying this prescription curative effect to patient in various degree and the safety of therapeutic process further, choose 100 examples Out-patient, 100 example patients are randomly divided into comparison II group and treatment each 50 examples of II group, comparison the II group age 21-41 year, put down All the age be (27.6 ± 7.4) year, the course of disease 8 months to 8 years, average course of disease is (4.5 ± 1.2) year, accompanies infertile person 13 example, ovary Cyst person 10 example, pelvic hydrops person 26 example;Treatment II group patient age 22-43 year, the mean age be (28.2 ± 7.8) year, The course of disease 6 months-7 years, average course of disease is (4.7 ± 1.3 years), accompanies infertile person 15 example, and ovarian cyst person 10 example, pelvic hydrops person 25 Example, two groups of patients the ordinary circumstances such as age, the course of disease, state of an illness classification relatively in, no significant difference (P > 0.05), tool There is comparability.Treatment II group gives the treatment of this prescription, and comparison II group gives metronidazole, health woman's inflammation capsule and BAOFUKANG SHUAN.Treatment statistics The results are shown in Table 2:
The therapeutic effect synopsis of table 2 patient in various degree
To sum up, use this prescription that all ages and classes, sufferer in various degree are respectively provided with higher therapeutic effect, and side effect Few, usage safety performance is high.
Although as it has been described above, represented and described the present invention with reference to specific preferred embodiment, but it must not be explained For the restriction to the present invention self.Under the spirit and scope of the present invention premise defined without departing from claims, can be right Various changes can be made in the form and details for it.

Claims (4)

1. one kind for treating the Chinese medicine composition of pelvic inflammatory disease, it is characterised in that includes following component: Flos Lonicerae, Herba Taraxaci, Huang A kind of reed mentioned in ancient books, Radix Bupleuri, Radix Paeoniae Rubra, Cortex Moutan, Radix Salviae Miltiorrhizae, Caulis Sargentodoxae, Herba Patriniae, Semen Coicis and Herba Plantaginis.
Chinese medicine composition for treating pelvic inflammatory disease the most according to claim 1, it is characterised in that include following component: gold Flos Lonicerae 10-15g, Herba Taraxaci 10-15g, Radix Scutellariae 10-15g, Radix Bupleuri 10-15g, Radix Paeoniae Rubra 10-15g, Cortex Moutan 10-15g, Radix Salviae Miltiorrhizae 10- 15g, Caulis Sargentodoxae 10-15g, Herba Patriniae 10-15g, Semen Coicis 10-15g and Herba Plantaginis 10-15g.
Chinese medicine composition for treating pelvic inflammatory disease the most according to claim 1, it is characterised in that include following component: gold Flos Lonicerae 12g, Herba Taraxaci 13g, Radix Scutellariae 12g, Radix Bupleuri 11g, Radix Paeoniae Rubra 14g, Cortex Moutan 14g, Radix Salviae Miltiorrhizae 10g, Caulis Sargentodoxae 11g, Herba Patriniae 15g, Semen Coicis 14g and Herba Plantaginis 12g.
4. Chinese medicine composition the answering in the medicine of preparation treatment pelvic inflammatory disease for treating pelvic inflammatory disease described in claim 1 With.
CN201610626531.0A 2016-08-01 2016-08-01 A kind of Chinese medicine composition for treating pelvic inflammatory disease Pending CN106138881A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991526A (en) * 2019-07-25 2020-11-27 王晓兵 A Chinese medicinal granule for treating pelvic inflammatory disease, and its preparation method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103417695A (en) * 2012-05-18 2013-12-04 孙冰清 Traditional Chinese medicine for treating chronic pelvic inflammation

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103417695A (en) * 2012-05-18 2013-12-04 孙冰清 Traditional Chinese medicine for treating chronic pelvic inflammation

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XWK20113: "妇科经验方", 《豆丁网》 *
周秀桃: "棱莪消积汤加味治疗盆腔炎", 《湖北中医杂志》 *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991526A (en) * 2019-07-25 2020-11-27 王晓兵 A Chinese medicinal granule for treating pelvic inflammatory disease, and its preparation method

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Application publication date: 20161123