CN106138315A - Wild lotus lozenge and preparation method thereof - Google Patents

Wild lotus lozenge and preparation method thereof Download PDF

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Publication number
CN106138315A
CN106138315A CN201610649527.6A CN201610649527A CN106138315A CN 106138315 A CN106138315 A CN 106138315A CN 201610649527 A CN201610649527 A CN 201610649527A CN 106138315 A CN106138315 A CN 106138315A
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China
Prior art keywords
condensate liquid
wild
rosa roxburghii
lozenge
honey
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CN201610649527.6A
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Chinese (zh)
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许备占
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Individual
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Priority to CN201610649527.6A priority Critical patent/CN106138315A/en
Publication of CN106138315A publication Critical patent/CN106138315A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of wild lotus lozenge and preparation method thereof, wherein, the component of following weight portion is mainly included: Wild cottonrose hibiscus extract oil 40~50, China pink condensate liquid 10~20, Common Borage condensate liquid 10~20, purple perilla condensate liquid 10~20, Rosa roxburghii honey ointment 10~20 and pectin 15~25;Wherein, described Rosa roxburghii honey ointment is obtained with honey hybrid process by Rosa roxburghii.This lozenge has beauty treatment, nourishes, regulates body immunity, reduces MCO, make coronary artery and cerebrovascular bleeding capacity increase and improve effect of circulating function.

Description

Wild lotus lozenge and preparation method thereof
Technical field
The present invention relates to technical field of Chinese patent medicine, particularly relate to a kind of wild lotus lozenge.
Background technology
Wild Flos Hibisci Mutabilis has another name called sunset abelmoschus flower, is a kind of herbaceous plant, is grown between the gap of precipice, remote mountains.According to Compendium of Material Medica and " TCM Recipe pharmacy " is recorded, the concrete clearing heat and cooling blood of this plant, disappear alleviate pain, the effect such as moisten the lung and relieve the cough.According to modern medicine study Prove, the root of wild lotus, stem, leaf, flower, son contain various bioactivators, these active materials have beauty treatment, nourishing, Regulation body immunity, reduce MCO, make coronary artery and cerebrovascular bleeding capacity increase and improve circulating function Effect, simultaneously it or natural, can anti-aging, alleviate the biological actions such as anxiety, be health food, beverage, Medicine, the primary raw material of skincare product.But, current people are little to the exploitation dynamics of wild lotus, and market in this respect is deposited In very big blank.And prior art is abundant not to the extraction of active principle in plant, the life being easily destroyed in plant Active substances so that it is health care do not reach due effect.
Content of the invention
It is an object of the invention to solve at least the above and/or defect, and provide at least following excellent by illustrate Point.
It is an object of the present invention to provide a kind of wild lotus lozenge, can improve looks, nourish, regulate body immunity, fall Low MCO, makes coronary artery, cerebrovascular bleeding capacity increase, improves circulating function.
It is a further object of the invention to provide one can fully extract its bioactivator and can be kept it The preparation method of the health care buccal tablets of activity.
Other purposes with some for achieving the above object, the present invention adopts the following technical scheme that
A kind of wild lotus lozenge, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil 40~50, China pink condensate liquid 10~20, Common Borage condensate liquid 10~20, purple perilla condensate liquid 10~ 20th, Rosa roxburghii honey ointment 10~20 and pectin 15~25;
Wherein, described Rosa roxburghii honey ointment is obtained with honey hybrid process by Rosa roxburghii.
Preferably, described wild lotus lozenge, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil the 45th, China pink condensate liquid the 15th, Common Borage condensate liquid the 15th, purple perilla condensate liquid the 15th, Rosa roxburghii honey ointment 15 and Pectin 20.
Preferably, described wild lotus lozenge, wherein, the preparation method of described Rosa roxburghii honey ointment is: by 6~8 weight portions Rosa roxburghii and the mixing of 2~4 weight portion honey are brewed into paste, obtain described Rosa roxburghii honey ointment.A kind of wild cottonrose hibiscus as claimed in claim 1 The preparation method of Rong's lozenge, wherein, mainly comprises the steps that
Step 1, to wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf sterilization, irradiate 20 respectively under ultraviolet light~ 30 minutes;
Described wild lotus seed is carried out described wild lotus is obtained by extraction by step 2, employing supercritical CO 2 extraction technology Essential oil;
Step 3, carry out hot blast gradient drying respectively to phyllostachys nuda leaf, borage flower and perilla leaf, dry temperature and be followed successively by 65~60 DEG C, 59~55 DEG C, 48~44 DEG C, 40~35 DEG C, the drying time of each thermograde be followed successively by 57~52min, 126 ~180min, 214~240min, 275~300min, obtain boil-off gas;
Step 4, described boil-off gas is condensed, respectively obtain China pink condensate liquid, Common Borage condensate liquid and purple perilla Condensate liquid;
Step 5, by described Common Borage condensate liquid, purple perilla condensate liquid, China pink condensate liquid, Wild cottonrose hibiscus extract oil, Rosa roxburghii honey ointment with And pectin mixes, compacting obtains wild lotus lozenge.
The present invention at least includes following beneficial effect: first, the invention provides a kind of wild lotus lozenge, by by open country cottonrose hibiscus Rong's dew mixes with China pink condensate liquid, purple perilla condensate liquid, Common Borage condensate liquid, Rosa roxburghii honey ointment and pectin, makes described lozenge have Improve looks, nourish, regulate body immunity, reduce MCO, make coronary artery and cerebrovascular bleeding capacity increase and improve Effect of circulating function.Secondly, the present invention is by using the system of supercritical carbon dioxide extraction method and hot blast gradient oven drying method Making method and extracting Wild cottonrose hibiscus extract oil, the Wild cottonrose hibiscus extract oil purity making extraction is higher;Hot blast gradient oven drying method remains in plant more Many bioactivators, make wild lotus lozenge improve looks, nourish, regulate body immunity, reduce MCO, make crown moving Arteries and veins and cerebrovascular bleeding capacity increase and improve effect of circulating function and bring into play more fully and the open country made of the present invention Lotus lozenge instant, taste is sweet, taste lubrication.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by this Invention research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is elaborated, after making those of ordinary skill in the art refer to this specification Can implement according to this.
A kind of wild lotus lozenge, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil 40~50, China pink condensate liquid 10~20, Common Borage condensate liquid 10~20, purple perilla condensate liquid 10~ 20th, Rosa roxburghii honey ointment 10~20 and pectin 15~25;
Wherein, described Rosa roxburghii honey ointment is obtained with honey hybrid process by Rosa roxburghii.
Described wild lotus lozenge, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil the 45th, China pink condensate liquid the 15th, Common Borage condensate liquid the 15th, purple perilla condensate liquid the 15th, Rosa roxburghii honey ointment 15 and Pectin 20.
Described wild lotus lozenge, wherein, the preparation method of described Rosa roxburghii honey ointment is: by 6~8 weight portion Rosa roxburghiis and 2~4 The mixing of weight portion honey is brewed into paste, obtains described Rosa roxburghii honey ointment.Described wild lotus has to disappear and alleviates pain, moistens the lung and relieve the cough etc. Effect.
Described China pink has reducing fever and causing diuresis, and broken blood stimulates the menstrual flow, and dissipates the swollen effect of stagnation resolvation.
Described Common Borage has removing toxic substances, the effect of physical function running of bringing down a fever, recover
Described Rosa roxburghii have anticancer reduction cholesterol, anti arteriosclerosis, suppression metastases, reduce Incidence of CHD, Improve the effects such as immunity.
Described honey has promotion regeneration, and promotion digests, improves immunity, protects cardiovascular effect.
Described component mixing can make beauty treatment, nourish, regulate body immunity, reduce MCO, make coronary artery and The efficacy exertion that cerebrovascular bleeding capacity increases and improve circulating function etc. is stablized and strengthens.
The preparation method of a kind of wild lotus lozenge as claimed in claim 1, wherein, mainly comprises the steps that
Step 1, to wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf sterilization, irradiate 20 respectively under ultraviolet light~ 30 minutes;
Described wild lotus seed is carried out described wild lotus is obtained by extraction by step 2, employing supercritical CO 2 extraction technology Essential oil;
Step 3, carrying out hot blast gradient drying respectively to phyllostachys nuda leaf, borage flower and perilla leaf, temperature is followed successively by 65~ 60 DEG C, 59~55 DEG C, 48~44 DEG C, 40~35 DEG C, drying time be followed successively by 57~52min, 126~180min, 214~ 240min, 275~300min, obtain boil-off gas;
Step 4, described boil-off gas is condensed, respectively obtain China pink condensate liquid, Common Borage condensate liquid and purple perilla Condensate liquid;
Step 5, by described Common Borage condensate liquid, purple perilla condensate liquid, China pink condensate liquid, Wild cottonrose hibiscus extract oil, Rosa roxburghii honey ointment with And pectin mixes, compacting obtains wild lotus lozenge.
Embodiment 1
1st, to wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf sterilization, irradiate 25 minutes under ultraviolet light respectively
2nd, be dried open country lotus seed, pulverize, sieving obtains raw meal, is then obtained by supercritical CO 2 extraction technology To 45g Wild cottonrose hibiscus extract oil.
3rd, phyllostachys nuda leaf, borage flower and perilla leaf are dried respectively at 65 DEG C 52min, dry at 59 DEG C 126min, dries DEG C 214min at 48 DEG C, dries 275min at 40 DEG C, and when then will dry, steam is cold by condensing unit Coagulate and obtain 15g China pink condensate liquid, 15g Common Borage condensate liquid and 15g purple perilla condensate liquid.
4th, Rosa roxburghii is cleaned, then according to the ratio that Rosa roxburghii and honey are 2:1 adds honey, be brewed into paste and obtain 15g Rosa roxburghii honey ointment
5th, Wild cottonrose hibiscus extract oil, China pink condensate liquid, Common Borage condensate liquid, purple perilla condensate liquid and Rosa roxburghii honey ointment are mixed, and The compression of 20g pectin is added to make 125 buccal tablets.
Embodiment 2
1st, to wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf sterilization, irradiate 20 minutes under ultraviolet light respectively
2nd, be dried open country lotus seed, pulverize, sieving obtains raw meal, is then obtained by supercritical CO 2 extraction technology To 40g Wild cottonrose hibiscus extract oil.
3rd, phyllostachys nuda leaf, borage flower and perilla leaf are dried respectively at 60 DEG C 55min, dry at 55 DEG C 180min, dries DEG C 240min at 44 DEG C, dries 300min at 35 DEG C, and when then will dry, steam is cold by condensing unit Coagulate and obtain 10g China pink condensate liquid, 10g Common Borage condensate liquid and 10g purple perilla condensate liquid.
4th, Rosa roxburghii is cleaned, then according to the ratio that Rosa roxburghii and honey are 7:3 adds honey, be brewed into paste and obtain 10g Rosa roxburghii honey ointment.
5th, Wild cottonrose hibiscus extract oil, China pink condensate liquid, Common Borage condensate liquid, purple perilla condensate liquid and Rosa roxburghii honey ointment are mixed, and The compression of 15g pectin is added to make 95 buccal tablets.
Embodiment 3
1st, to wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf sterilization, irradiate 30 minutes under ultraviolet light respectively
2nd, be dried open country lotus seed, pulverize, sieving obtains raw meal, is then obtained by supercritical CO 2 extraction technology To 50g Wild cottonrose hibiscus extract oil.
3rd, phyllostachys nuda leaf, borage flower and perilla leaf are dried respectively at 65 DEG C 52min, dry at 59 DEG C 126min, dries DEG C 214min at 48 DEG C, dries 275min at 40 DEG C, and when then will dry, steam is cold by condensing unit Coagulate and obtain 20g phyllostachys nuda leaf condensate liquid, 20g Common Borage condensate liquid and 20g purple perilla condensate liquid.
4th, Rosa roxburghii is cleaned, then according to Rosa roxburghii and honey are 3:1 ratio adds honey, are brewed into paste and obtain 20g thorn Pears honey ointment
5th, Wild cottonrose hibiscus extract oil, China pink condensate liquid, Common Borage condensate liquid, purple perilla condensate liquid and Rosa roxburghii honey ointment are mixed, and 25g pectin glue laminated contraction is added to become 155 buccal tablets.
Although embodiment of the present invention are disclosed as above, but it is not restricted in specification and embodiment listed Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily Realizing other modification, therefore under the universal being limited without departing substantially from claim and equivalency range, the present invention does not limit In specific details.

Claims (4)

1. a wild lotus lozenge, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil 40~50, China pink condensate liquid 10~20, Common Borage condensate liquid 10~20, purple perilla condensate liquid 10~20, thorn Pears honey ointment 10~20 and pectin 15~25;
Wherein, described Rosa roxburghii honey ointment is obtained with honey hybrid process by Rosa roxburghii.
2. lotus lozenge as claimed in claim 1 wild, wherein, mainly includes the component of following weight portion:
Wild cottonrose hibiscus extract oil the 45th, China pink condensate liquid the 15th, Common Borage condensate liquid the 15th, purple perilla condensate liquid the 15th, Rosa roxburghii honey ointment 15 and pectin 20。
3. wild lotus lozenge as claimed in claim 1, wherein, the preparation method of described Rosa roxburghii honey ointment is: by 6~8 weight portions Rosa roxburghii and the mixing of 2~4 weight portion honey are brewed into paste, obtain described Rosa roxburghii honey ointment.
4. a preparation method for wild lotus lozenge as claimed in claim 1, wherein, mainly comprises the steps that
Step 1, wild lotus seed, phyllostachys nuda leaf, borage flower and perilla leaf are carried out disinfection respectively;
Described wild lotus seed is carried out described Wild cottonrose hibiscus extract oil is obtained by extraction by step 2, employing supercritical CO 2 extraction technology;
Step 3, carry out hot blast gradient drying respectively to phyllostachys nuda leaf, borage flower and perilla leaf, dry temperature be followed successively by 65~ 60 DEG C, 59~55 DEG C, 48~44 DEG C, 40~35 DEG C, the drying time of each thermograde be followed successively by 57~52min, 126~ 180min, 214~240min, 275~300min, obtain boil-off gas;
Step 4, described boil-off gas is condensed, respectively obtain China pink condensate liquid, Common Borage condensate liquid and purple perilla condensation Liquid;
Step 5, by described Common Borage condensate liquid, purple perilla condensate liquid, China pink condensate liquid, Wild cottonrose hibiscus extract oil, Rosa roxburghii honey ointment and fruit Glue mixing, compacting obtain wild lotus lozenge.
CN201610649527.6A 2016-08-09 2016-08-09 Wild lotus lozenge and preparation method thereof Pending CN106138315A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800007395A1 (en) * 2018-07-20 2020-01-20 COMPOSITION BASED ON ESSENTIAL OILS

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1131517A (en) * 1995-03-20 1996-09-25 王凌 Wild cottonrose hibiscus material
CN1383844A (en) * 2001-05-08 2002-12-11 王绍璋 Wild hibiscus Chinese medicine material and herbal pieces
CN101181390A (en) * 2007-11-27 2008-05-21 山东大学 Roxburgh rose juice buccal tablets
CN101933567A (en) * 2010-05-12 2011-01-05 谈小伦 Golden pomelo sugar-free mint lozenge and preparation method thereof
CN102641319A (en) * 2012-04-03 2012-08-22 浙江农林大学 Buccal tablet with dried particles of flower buds of Chrysanthe memindieum and preparing method thereof
CN103952240A (en) * 2014-05-19 2014-07-30 安徽科技学院 Preparation method of abelmoschus manihot essential oil

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1131517A (en) * 1995-03-20 1996-09-25 王凌 Wild cottonrose hibiscus material
CN1383844A (en) * 2001-05-08 2002-12-11 王绍璋 Wild hibiscus Chinese medicine material and herbal pieces
CN101181390A (en) * 2007-11-27 2008-05-21 山东大学 Roxburgh rose juice buccal tablets
CN101933567A (en) * 2010-05-12 2011-01-05 谈小伦 Golden pomelo sugar-free mint lozenge and preparation method thereof
CN102641319A (en) * 2012-04-03 2012-08-22 浙江农林大学 Buccal tablet with dried particles of flower buds of Chrysanthe memindieum and preparing method thereof
CN103952240A (en) * 2014-05-19 2014-07-30 安徽科技学院 Preparation method of abelmoschus manihot essential oil

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800007395A1 (en) * 2018-07-20 2020-01-20 COMPOSITION BASED ON ESSENTIAL OILS

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