CN106124496B - A kind of monitoring material and its preparation method and application based on graphene oxide - Google Patents
A kind of monitoring material and its preparation method and application based on graphene oxide Download PDFInfo
- Publication number
- CN106124496B CN106124496B CN201610463573.7A CN201610463573A CN106124496B CN 106124496 B CN106124496 B CN 106124496B CN 201610463573 A CN201610463573 A CN 201610463573A CN 106124496 B CN106124496 B CN 106124496B
- Authority
- CN
- China
- Prior art keywords
- graphene oxide
- monitoring
- monitoring material
- temperature
- mixed liquor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K11/00—Measuring temperature based upon physical or chemical changes not covered by groups G01K3/00, G01K5/00, G01K7/00 or G01K9/00
- G01K11/12—Measuring temperature based upon physical or chemical changes not covered by groups G01K3/00, G01K5/00, G01K7/00 or G01K9/00 using changes in colour, translucency or reflectance
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Plasma & Fusion (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
The present invention relates to a kind of monitoring material and its preparation method and application based on graphene oxide, more particularly to the monitoring material to temperature and/or light sensitive, belong to the monitoring technical field of perishable food, drug or vaccine, which is the illumination stored in a warehouse for Cold Chain Logistics based on graphene oxide and temperature monitoring material.Monitoring material of the invention is that graphene oxide, catalysis material, reducing agent (are dispersed in water to obtain mixed liquor, mixed liquor sufficiently be dried, to obtain the mixture of above-mentioned three classes material.The material is in yellow under As-deposited state, under the conditions of illumination or higher temperature (> 8 DEG C), the color of material is gradually converted into dark yellow so that black, color change has the characteristics that irreversible, to realize a kind of material while monitor the effect of illumination and temperature, which is protected from light in needs, the Cold Chain Logistics of low temperature, storage field are with important application prospects.
Description
Technical field
The present invention relates to a kind of monitoring material and its preparation method and application based on graphene oxide, and in particular to temperature
The monitoring material of degree and/or light sensitive, belongs to the monitoring technical field of perishable food, drug or vaccine, which is to use
Illumination based on graphene oxide and temperature monitoring material in Cold Chain Logistics storage.
Background technique
Currently, a large amount of vaccine, drug and food are required to be stored in a warehouse under the conditions of low temperature and the cold chain being protected from light, be transported
With use.If wherein some part is due to equipment fault etc., make article departing from cold chain environment, corresponding article character will
It changes.But in the prior art, after corresponding article character changes, because obviously prompting or identifying without corresponding,
User is not easy to find, thus the personal safety of critical vaccine, drug or food user.For example, in the vaccine event of Shandong,
Even veteran doctor, when carrying out vaccine inoculation, since vaccine does not identify accordingly, also go to judge without consciousness
Whether vaccine is gone bad or is failed.
Summary of the invention
Technology of the invention solves the problems, such as: overcome the deficiencies in the prior art, proposes a kind of prison based on graphene oxide
Measure and monitor the growth of standing timber material and its preparation method and application.
The technical solution of the invention is as follows:
A kind of monitoring material based on graphene oxide, the form of the monitoring material are powder, film or block, including oxygen
Graphite alkene, catalysis material and reducing agent；
The graphene oxide, catalysis material, reducing agent mass ratio be 0.5-10:0.1-2:0.1-2；
The catalysis material is the mixture of one or both of titanium dioxide or zinc oxide；
The reducing agent is the mixture of one or more of glucose, maltose, fructose or vitamin C.
A kind of preparation method of the monitoring material based on graphene oxide, step are as follows:
(1) graphene oxide, catalysis material are added to the water, be protected from light, low temperature (1~6 DEG C) under the conditions of ultrasonic disperse 5
~60 minutes, obtain the mixed liquor I of uniform component；
(2) reducing agent is added in the mixed liquor I that step (1) obtains, ultrasonic disperse 1~5 minute, obtains uniform component
Mixed liquor II；
(3) mixed liquor II for obtaining step (2) carries out low temperature drying processing, obtains the monitoring material based on graphene oxide
Material, obtained monitoring material are yellow.
The concentration of graphene oxide is 0.5g/L~10g/L in the step (2), and the concentration of catalysis material is
0.1g/L~2g/L, the concentration of reducing agent are 0.1g/L~2g/L；
The temperature that low temperature drying is handled in the step (3) is 1~6 DEG C；
The mode being dried in the step (3) is atomization drying, suction filtration or convection drying, obtained monitoring material
For powdered, film or bulk.
A kind of application of the monitoring material based on graphene oxide, step are as follows: the monitoring based on graphene oxide
Material is applied to be protected from light or the monitoring of low-temperature storage article needs；Described be protected from light refers to and avoids solar radiation, and described is low
Temperature refers to temperature not higher than 8 DEG C；The needs are protected from light or low-temperature storage article refers to food, drug or vaccine；
The application of the described monitoring material, refer to will monitor be fixed on after material is packaged with packaging material it is described to
It monitors on article or its outer package surface；
The packaging material is transparent plastic or glass；
It is described be fixed as pasting or with article or packaging integrated plastic packaging to be monitored.
Beneficial effect
(1) monitoring material of the invention when illuminated, effect of the graphene oxide in catalysis material and reducing agent
Under, the transformation to graphene occurs, color is also correspondingly changed into dark yellow so that black from yellow；
(2) monitoring material of the invention be protected from light, higher temperature (> 8 DEG C) under the conditions of, graphene oxide in the material
It is reacted with reducing agent and the transformation to graphene occurs, correspondingly, the color of material is also changed into dark yellow from yellow with blackening
Color；
(3) monitoring material of the invention can reach the monitoring effect of illumination and temperature simultaneously；
(4) when by illumination or in higher temperature conditions, the change procedure of color has monitoring material of the invention
Irreversibility；
(5) monitoring material of the invention by illumination or be in higher temperature conditions when, with light application time or in compared with
The increase of time under high-temperature monitors deepening with additive for material color；
(6) raw material of monitoring material of the invention is nontoxic, harmless, non-volatile, easily encapsulate, and be not easy with it is to be monitored
Article or packaging chemically react, and are free from side effects to article to be monitored；
(7) monitoring material of the invention is before needing to be protected from light, the Cold Chain Logistics of low temperature storage field has important application
Scape, can be used for the material of temperature and illumination monitoring simultaneously, to meet in cold chain storage, transport and use process simultaneously to temperature
With the demand of the dual monitoring of illumination.
(8) monitoring material of the invention is by graphene oxide, catalysis material (in titanium dioxide and Zinc oxide powder
One or two kinds of mixtures), reducing agent (mixture of one or more of glucose, maltose, fructose and vitamin C)
It is dispersed in water to obtain mixed liquor, mixed liquor is sufficiently dry, to obtain the mixture of above-mentioned three classes material.It should under As-deposited state
Material is in yellow, and under the conditions of illumination or higher temperature (> 8 DEG C), the color of material is gradually converted into dark yellow so that black, face
Color change has the characteristics that irreversible, to realize a kind of material while monitor the effect of illumination and temperature, which is being needed
Be protected from light, the Cold Chain Logistics of low temperature, storage field it is with important application prospects.
(9) due to emphasizing need to be protected from light in the outer packing of many vaccines, drug and food in the prior art, low-temperature storage,
But the indicating label of illumination and temperature monitoring is had not been used in packaging etc.；It is of the invention with illumination and temperature monitoring performance
Material is encapsulated in the packaging of vaccine, drug or food etc., once article is departing from cold chain environment, monitoring material will be sent out
Raw irreversible color change can intuitively prompt storage conveying people or user to pay close attention to the change of article character, thus will
The application risk for being detached from cold chain article is greatly reduced.
Detailed description of the invention
Fig. 1 is the monitoring material of As-deposited state in embodiment 1, and color is in yellow；
Fig. 2 is to monitor material in embodiment 1 to irradiate the photo after 8 hours in the sunlight, and color is in black.
Specific embodiment
The present invention is described further with reference to the accompanying drawings and examples.
Embodiment 1
(1) by 10g graphene oxide, 0.5g titanium dioxide be added 1L water in, be protected from light, 6 DEG C under the conditions of ultrasonic disperse 30
Minute, obtain the mixed liquor I of uniform component；Further, the addition 0.1g glucose in above-mentioned mixed liquor, ultrasonic disperse 5 minutes,
Obtain the mixed liquor II of uniform component；
(2) above-mentioned mixed liquor II is obtained under the conditions of 6 DEG C film-form by suction method and monitors material.Under As-deposited state,
The color of material is yellow, as shown in Figure 1；
(3) obtained yellow film shape monitoring material is fixed on to the outer package surface of vaccine to be monitored with plastics package
On；
(4) vaccine with yellow film shape monitoring material for obtaining step (3) irradiates 8 hours in the sunlight, monitors
The color transition of material is black, as shown in Fig. 2, showing that the monitoring material has good illumination indicating effect, while also being mentioned
Show that vaccine has received illumination or the raising of temperature, needs further to check whether vaccine fails or go bad.
Embodiment 2
(1) by 0.5g graphene oxide, 0.05g titanium dioxide and 0.05g zinc oxide be added 1L water in, be protected from light, 1 DEG C of item
Ultrasonic disperse 5 minutes under part, obtain the mixed liquor I of uniform component；Further, 0.1g fructose is added in above-mentioned mixed liquor, surpasses
Sound disperses 1 minute, obtains the mixed liquor II of uniform component；
(2) above-mentioned mixed liquor II is obtained into powdered monitoring material by atomization drying method.Under As-deposited state, the face of material
Color is yellow；
(3) obtained yellow powder monitoring material is fixed on to the outer package surface of drug to be monitored with glass packaging
On；
(4) by step (3) obtain with yellow powder monitoring material drug be protected from light, 30 DEG C save 24 hours,
Color transition is buff, shows that the monitoring material has good illumination indicating effect, while also prompt drug has been subjected to
The raising of illumination or temperature, needs further to check whether drug fails or go bad.
Embodiment 3
(1) 10g graphene oxide, 1g titanium dioxide and 1g zinc oxide are added in 1L water, be protected from light, 4 DEG C under the conditions of it is super
Sound disperses 60 minutes, obtain the mixed liquor I of uniform component；Further, in above-mentioned mixed liquor be added 0.025g glucose,
0.025g maltose, 0.025g fructose, 0.025g vitamin C ultrasonic disperse 5 minutes, obtain the mixed liquor of uniform component；
(2) above-mentioned mixed liquor II is obtained into bulk material as temperature monitoring material by cold drying.In As-deposited state
Under, the color of material is yellow；
(3) obtained yellow bulk monitoring material is fixed on to the outer package surface of food to be monitored with plastics package
On；
(4) food with yellow bulk monitoring material for obtaining step (3) saves 2 hours in daylight, 25 DEG C, color
It is changed into buff, shows that the monitoring material has good illumination indicating effect, while also prompt food has received light
According to or temperature raising, need further to check whether food fails or go bad.
Embodiment 4
(1) by 10g graphene oxide, 2g zinc oxide be added 1L water in, be protected from light, 6 DEG C under the conditions of ultrasonic disperse 10 minutes,
Obtain the mixed liquor I of uniform component；Further, 2g maltose is added in above-mentioned mixed liquor, ultrasonic disperse 1 minute, obtains into
Divide uniform mixed liquor II；
(2) above-mentioned mixed liquor II is obtained under the conditions of 3 DEG C film-form by suction method and monitors material.Under As-deposited state,
The color of material is yellow；
(3) obtained yellow film shape monitoring material is fixed on to the outer package surface of vaccine to be monitored with plastics package
On；
(4) vaccine with yellow film shape monitoring material for obtaining step (3) irradiates 4 hours in the sunlight, monitors
The color transition of material is buff, shows that the monitoring material has good illumination indicating effect, while also having prompted vaccine
It has been subjected to illumination or the raising of temperature, has needed further to check whether vaccine fails or go bad.
Embodiment 5
(1) by 5g graphene oxide, 0.5g titanium dioxide and 0.5g zinc oxide be added 1L water in, be protected from light, 2 DEG C under the conditions of
Ultrasonic disperse 40 minutes, obtain the mixed liquor I of uniform component；Further, 1g vitamin C, ultrasound are added in above-mentioned mixed liquor
Dispersion 2 minutes, obtains the mixed liquor of uniform component；
(2) above-mentioned mixed liquor II is obtained into bulk material as temperature monitoring material by cold drying.In As-deposited state
Under, the color of material is yellow；
(3) obtained yellow bulk monitoring material is fixed on to the outer package surface of food to be monitored with plastics package
On；
(4) food with yellow bulk monitoring material for obtaining step (3) saves 10 hours in daylight, 30 DEG C, face
Color is changed into black, shows that the monitoring material has good illumination indicating effect, while also prompt food has received light
According to or temperature raising, need further to check whether food fails or go bad.
Embodiment 6
(1) by 2g graphene oxide, 0.2g zinc oxide be added 1L water in, be protected from light, 1 DEG C under the conditions of ultrasonic disperse 5 minutes,
Obtain the mixed liquor I of uniform component；Further, 0.1g fructose and 0.2g glucose, ultrasonic disperse 2 are added in above-mentioned mixed liquor
Minute, obtain the mixed liquor II of uniform component；
(2) above-mentioned mixed liquor II is obtained into powdered monitoring material by atomization drying method.Under As-deposited state, the face of material
Color is yellow；
(3) obtained yellow powder monitoring material is fixed on to the outer package surface of drug to be monitored with glass packaging
On；
(4) by step (3) obtain with yellow powder monitoring material drug be protected from light, 40 DEG C save 48 hours,
Color transition is black, shows that the monitoring material has good illumination indicating effect, while also prompt drug has received
Illumination or the raising of temperature need further to check whether drug fails or go bad.
Embodiment 7
(1) by 8g graphene oxide, 0.2g titanium dioxide and 0.1g zinc oxide be added 1L water in, be protected from light, 3 DEG C under the conditions of
Ultrasonic disperse 10 minutes, obtain the mixed liquor I of uniform component；Further, 0.5g glucose, 0.1g are added in above-mentioned mixed liquor
Maltose and 0.5g vitamin C ultrasonic disperse 1 minute, obtain the mixed liquor II of uniform component；
(2) above-mentioned mixed liquor II is obtained into powdered monitoring material by atomization drying method.Under As-deposited state, the face of material
Color is yellow；
(3) obtained yellow powder monitoring material is fixed on to the outer package surface of vaccine to be monitored with plastics package
On；
(4) vaccine with yellow powder monitoring material for obtaining step (3) saves 10 hours in daylight, 35 DEG C,
Color transition is black, shows that the monitoring material has good illumination indicating effect, while also prompt vaccine has received
Illumination or the raising of temperature need further to check whether vaccine fails or go bad.
Claims (9)
1. a kind of monitoring material based on graphene oxide, it is characterised in that: the monitoring material includes graphene oxide, photocatalysis
Material and reducing agent；
The catalysis material is the mixture of one or both of titanium dioxide or zinc oxide；
The reducing agent is the mixture of one or more of glucose, maltose, fructose or vitamin C；
The monitoring material can be applied to be protected from light or the monitoring of low-temperature storage article needs；
Described be protected from light refers to and avoids solar radiation, and the low temperature refers to temperature not higher than 8 DEG C.
2. a kind of monitoring material based on graphene oxide according to claim 1, it is characterised in that: the oxidation stone
Black alkene, catalysis material, reducing agent mass ratio be 0.5-10:0.1-2:0.1-2.
3. a kind of application of monitoring material based on graphene oxide according to claim 1, it is characterised in that: described
It needs to be protected from light or low-temperature storage article refers to food or drug.
4. a kind of application of monitoring material based on graphene oxide according to claim 1, it is characterised in that: described
Monitoring material is fixed on article to be monitored or its outer package surface in use, will monitor after material is packaged with packaging material
On.
5. a kind of application of monitoring material based on graphene oxide according to claim 4, it is characterised in that: described
Packaging material is transparent plastic or glass；It is described be fixed as pasting or with article or packaging integrated plastic packaging to be monitored.
6. a kind of preparation method of any monitoring material based on graphene oxide of claim 1-5, it is characterised in that
Step are as follows:
(1) graphene oxide, catalysis material are added to the water, be protected from light, ultrasonic disperse under cryogenic conditions, obtain uniform component
Mixed liquor I；
(2) reducing agent is added in the mixed liquor I that step (1) obtains, ultrasonic disperse obtains the mixed liquor II of uniform component；
(3) mixed liquor II for obtaining step (2) carries out low temperature drying processing, obtains the monitoring material based on graphene oxide.
7. a kind of preparation method of monitoring material based on graphene oxide according to claim 6, it is characterised in that: institute
In the step of stating (1), low temperature is 1~6 DEG C, and the ultrasonic disperse time is 5~60min, and the catalysis material is titanium dioxide
Or the mixture of one or both of zinc oxide, the concentration of graphene oxide are 0.5g/L~10g/L, catalysis material it is dense
Degree is 0.1g/L~2g/L.
8. a kind of preparation method of monitoring material based on graphene oxide according to claim 6, it is characterised in that: institute
In the step of stating (2), the ultrasonic disperse time is 1~5min, and the concentration of reducing agent is 0.1g/L~2g/L, and the reducing agent is
The mixture of one or more of glucose, maltose, fructose or vitamin C.
9. a kind of preparation method of monitoring material based on graphene oxide according to claim 6, it is characterised in that: institute
In the step of stating (3), the temperature of low temperature drying processing is 1~6 DEG C, and the mode of drying process is atomization drying, suction filtration or direct
Dry, obtained monitoring material is yellow, and the form for monitoring material is powdered, film or bulk.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610463573.7A CN106124496B (en) | 2016-06-23 | 2016-06-23 | A kind of monitoring material and its preparation method and application based on graphene oxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610463573.7A CN106124496B (en) | 2016-06-23 | 2016-06-23 | A kind of monitoring material and its preparation method and application based on graphene oxide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106124496A CN106124496A (en) | 2016-11-16 |
| CN106124496B true CN106124496B (en) | 2018-12-21 |
Family
ID=57268062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610463573.7A Expired - Fee Related CN106124496B (en) | 2016-06-23 | 2016-06-23 | A kind of monitoring material and its preparation method and application based on graphene oxide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106124496B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130266628A1 (en) * | 2012-04-10 | 2013-10-10 | Indian Institute Of Technology Madras | Graphene-based antimicrobial composites |
| KR101946007B1 (en) * | 2012-06-20 | 2019-02-08 | 삼성전자주식회사 | Apparatus and Method for analyzing graphene |
| CN103879999B (en) * | 2014-03-03 | 2016-01-06 | 中国科学院合肥物质科学研究院 | Synchronous in-situ reducing graphene oxide prepares the method for composite |
| EP2924444A1 (en) * | 2014-03-28 | 2015-09-30 | AIT Austrian Institute of Technology GmbH | Flow and pressure sensitive graphene sensor |
-
2016
- 2016-06-23 CN CN201610463573.7A patent/CN106124496B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN106124496A (en) | 2016-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2904385B1 (en) | Indicator device | |
| US20160011157A1 (en) | Time Passage Indicator | |
| Zong et al. | Preparation and characterization of a novel intelligent starch/gelatin binary film containing purple sweet potato anthocyanins for Flammulina velutipes mushroom freshness monitoring | |
| CN106124496B (en) | A kind of monitoring material and its preparation method and application based on graphene oxide | |
| CN107647962A (en) | Cold and hot compress product with temperature warning function | |
| US20180327160A1 (en) | Track and trace packaging and systems | |
| CN2897869Y (en) | Packing bag | |
| WO2018129780A1 (en) | Antibacterial packaging film and processing method | |
| Yao et al. | Development of shrimp freshness indicating films by immobilizing red pitaya betacyanins and titanium dioxide nanoparticles in polysaccharide-based double-layer matrix | |
| CN104709567B (en) | Microwave-specific food package bag and manufacturing method thereof | |
| CN104473168A (en) | Processing method for increasing solubility and bioavailability of fat-soluble active component | |
| Chen et al. | Green food packaging with integrated functions of high-efficiency radiation cooling and freshness monitoring | |
| CN206358532U (en) | It is a kind of to prevent the vial of ultraviolet | |
| CN105513273A (en) | Children sleep monitoring alarm | |
| CN208665906U (en) | A kind of food pack | |
| CN108645847A (en) | A method of oxygen is detected based on unformed tungsten oxide/polymer hybridisation nano fibrous membrane | |
| CN106832708A (en) | A kind of hemostasis film formulation hydrolyzed under high temperature | |
| CN103743727B (en) | A kind of nitrite detection reagent | |
| CN203111759U (en) | Freshness protection package for young garlic shoot storage | |
| CN109187527A (en) | A kind of oxygen indicator and the method using oxygen indicator production oxygen instruction product | |
| CN101775222A (en) | Whey protein/TiO2 edible composite membrane and preparation method thereof | |
| CN202399599U (en) | Cold stamping forming medicinal composite hard sheet | |
| CN207204068U (en) | A kind of double source thermal coupling chemical chain gasification device based on microwave | |
| CN104792778B (en) | A kind of oxygen indicator preparation method | |
| AR082433A1 (en) | FOOD PRODUCT WITH FLAVOR ENCAPSULATE |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181221 Termination date: 20190623 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |