CN106110503A - A kind of implantable medical devices with MRI pattern and method of work thereof - Google Patents
A kind of implantable medical devices with MRI pattern and method of work thereof Download PDFInfo
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- CN106110503A CN106110503A CN201610440057.2A CN201610440057A CN106110503A CN 106110503 A CN106110503 A CN 106110503A CN 201610440057 A CN201610440057 A CN 201610440057A CN 106110503 A CN106110503 A CN 106110503A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/16—Screening or neutralising undesirable influences from or using, atmospheric or terrestrial radiation or fields
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
- A61N1/3718—Monitoring of or protection against external electromagnetic fields or currents
Abstract
The present invention relates to the method for work of a kind of implantable medical devices with MRI pattern, it comprises the following steps: step S11, and detection strong external magnetic field also judges whether to detect the existence of strong external magnetic field, if, enter step S12, if it does not, continue to repeat step S11；Step S12, record detects the time of strong external magnetic field and the state of pulse generator, and labelling is in strong magnetic field circumstance, and enters step S13；Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step S14；Step S15, the time of record strong external magnetic field disappearance and the state of pulse generator, labelling leaves strong magnetic field circumstance, and enters step S16；And step S16, switch to normal mode, labelling MRI mode switching event, and return step S11.The invention still further relates to a kind of implantable medical devices.
Description
Technical field
The present invention relates to medical apparatus and instruments correlative technology field, especially, relate to a kind of implantable medical devices
(Implantable Medical Device,IMD)。
Background technology
Implantable medical devices kind is a lot, such as cardiac pacemaker and defibrillator, embedded nerve stimulator, implanted flesh
Meat stimulator etc..Implantable medical devices generally comprises et al. Ke device and outer control device, between the two by two-way
Wireless telecommunications exchange information.
In existing technology, implantable medical devices typically utilizes battery to power, and sends spy by pulse generating circuit
Determine the boost pulse of frequency, specific target spot is stimulated, thus improve the symptom of patient.Described pulse generating circuit is usual
Including a DC-DC voltage conversion circuit.But, under strong magnetic field circumstance, such as under nuclear magnetic resonance (MRI) environment, this DC-DC
Core inductance in change in voltage circuit causes inductance value to decline owing to magnetic core is saturated, and this can affect pulse generating circuit and send
Boost pulse, thus impact to the therapeutic effect of patient and brings potential safety hazard.
Summary of the invention
The present invention provides the method for work of a kind of implantable medical devices that can automatically detect strong magnetic field circumstance and adopts
With the implantable medical devices of the method.
The method of work of a kind of implantable medical devices with MRI pattern, this implantable medical devices includes that one is internal
Implanting device and a peripheral control unit, and this et al. Ke device includes the component that pair of outer high-intensity magnetic field is sensitive；This is planted
Enter the method that the method for work of formula medical apparatus and instruments includes controlling this et al. Ke device；Wherein, this et al. Ke device of this control
Method comprise the following steps:
Step S11, detection strong external magnetic field also judges whether to detect the existence of strong external magnetic field, if it is, enter step
Rapid S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of et al. Ke device of strong external magnetic field, and labelling is in high-intensity magnetic field
Environment, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step
S14；
Step S15, the time of record strong external magnetic field disappearance and the state of et al. Ke device, labelling leaves high-intensity magnetic field ring
Border, and enter step S16；And
Step S16, switches to normal mode, labelling MRI mode switching event, and returns step S11.
According to the method for work of above-mentioned implantable medical devices, wherein, described control volume is implanted into the method for device and enters one
Step comprises the following steps:
Step S17, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S18, if it does not,
Continue to repeat step S17；
Step S18, it may be judged whether have MRI mode switching event, if it is, enter step S19, if it is not, then enter step
Rapid S22；
Step S19, sends MRI mode switching event relevant information to peripheral control unit, subsequently into step S20；
Step S20, waits the response of peripheral control unit, and enters step S21；
Step S21, resets MRI mode switching event labelling, and enters step S22；And
Step S22, terminates.
According to the method for work of above-mentioned implantable medical devices, wherein, the method for work of this implantable medical devices is also wrapped
Include the method controlling this peripheral control unit；The method of this control peripheral control unit comprises the following steps:
Step S23, sends inquiry instruction to et al. Ke device, and enters step S24；
Step S24, it may be judged whether receive the prompting of MRI mode switching event, if it is, enter step S25, if it does not,
Enter step S29；
Step S25, receives MRI mode switching event relevant information, subsequently into step S26；
Step S26, display MRI mode switching event prompting warning, subsequently into step S27；
Step S27, waits that user checks, and enters step S28；
Step S28, sends response to et al. Ke device, and enters step S29；And
Step S29, terminates.
The method of work of a kind of implantable medical devices with MRI pattern, this implantable medical devices includes that one is internal
Implanting device and a peripheral control unit, and this et al. Ke device includes the component that pair of outer high-intensity magnetic field is sensitive；This is planted
Enter the method that the method for work of formula medical apparatus and instruments includes controlling this et al. Ke device；Wherein, this et al. Ke device of this control
Method comprise the following steps:
Step S10, it may be judged whether receive the detection instruction of peripheral control unit, if it is, enter step S11, if it does not,
Continue to repeat step S10；
Step S11, starts detect strong external magnetic field and judge whether to detect the existence of strong external magnetic field, if it is, enter
Enter step S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of et al. Ke device of strong external magnetic field, and labelling is in high-intensity magnetic field
Environment, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step
S14；
Step S15, the time of record strong external magnetic field disappearance and the state of et al. Ke device, labelling leaves high-intensity magnetic field ring
Border, and enter step S16；
Step S16, switches to normal mode, labelling MRI mode switching event, and enters step S17；And
Step S17, stops detection strong external magnetic field, and returns step S10.
According to the method for work of above-mentioned implantable medical devices, wherein, in described step S17, described stopping detects outside
The method of high-intensity magnetic field comprises the following steps:
Step S171, it may be judged whether receive the stopping detection instruction of peripheral control unit, if it is, enter step S173,
If it does not, enter step S172；
Step S172, if more than a time threshold, if it is, enter step S173, if it does not, return step S171；
And
Step S173, stops detection strong external magnetic field.
According to the method for work of above-mentioned implantable medical devices, wherein, described control volume is implanted into the method for device and enters one
Step comprises the following steps:
Step S17A, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S18, if
No, continue to repeat step S17A；
Step S18, it may be judged whether have MRI mode switching event, if it is, enter step S19, if it is not, then enter step
Rapid S22；
Step S19, sends MRI mode switching event relevant information to peripheral control unit, subsequently into step S20；
Step S20, waits the response of peripheral control unit, and enters step S21；
Step S21, resets MRI mode switching event labelling, and enters step S22；And
Step S22, terminates.
According to the method for work of above-mentioned implantable medical devices, wherein, the method for work of this implantable medical devices is also wrapped
Include the method controlling this peripheral control unit；The method of this control peripheral control unit comprises the following steps:
Step S23, sends inquiry instruction to et al. Ke device, and enters step S24；
Step S24, it may be judged whether receive the prompting of MRI mode switching event, if it is, enter step S25, if it does not,
Enter step S29；
Step S25, receives MRI mode switching event relevant information, subsequently into step S26；
Step S26, display MRI mode switching event prompting warning, subsequently into step S27；
Step S27, waits that user checks, and enters step S28；
Step S28, sends response to et al. Ke device, and enters step S29；And
Step S29, terminates.
A kind of implantable medical devices with MRI pattern, comprising: a peripheral control unit and et al. Ke dress
Put；Including inside described et al. Ke device: a power module, a manostat, a DC-DC voltage conversion circuit, one controls electricity
Road, a magnetic field sensor and a communication module, wherein, the method for work of described implantable medical devices is implantation described above
Any one in the method for work of formula medical apparatus and instruments.
According to above-mentioned implantable medical devices, wherein, described magnetic field sensor include a magnetic field induction element and one with
The judge module of this magnetic field induction element electrical connection；Described judge module is according to the detection data of this magnetic field induction element, it is judged that
Whether existence can make the magnetic field that the energy storage inductor in described DC-DC voltage conversion circuit is saturated.
According to above-mentioned implantable medical devices, wherein, described magnetic field induction element is hall effect sensor；Or described magnetic
Field sensing element is the detecting element of the pulse generator internal circuit parameter of a detection described et al. Ke device, by described
The existence of the change presumption strong external magnetic field of pulse generator internal circuit parameter.
Compared to prior art, implantable medical devices and method of work thereof that the present invention provides can detect strong magnetic automatically
Environment, thus realize the switching of MRI pattern and normal mode, it is to avoid potential safety hazard, improves safety.
Accompanying drawing explanation
Fig. 1 is the structural representation of the lesions located in deep brain device that the embodiment of the present invention uses.
The block diagram of the pulse generator of the lesions located in deep brain device that Fig. 2 provides for the embodiment of the present invention.
The block diagram of the magnetic field sensor of the lesions located in deep brain device that Fig. 3 provides for the embodiment of the present invention.
The block diagram of the another kind of magnetic field sensor of the lesions located in deep brain device that Fig. 4 provides for the embodiment of the present invention.
The block diagram of the DC-DC voltage conversion circuit of the lesions located in deep brain device that Fig. 5 provides for the embodiment of the present invention.
The inductive current of the DC-DC voltage conversion circuit of the lesions located in deep brain device that Fig. 6 provides for the embodiment of the present invention exists
Normal work and comparing result when working under 3T nuclear-magnetism high-intensity magnetic field.
Fig. 7 is the feedback control circuit of the DC-DC voltage conversion circuit that the embodiment of the present invention uses.
Fig. 8 is the feedback including normal mode and the DC-DC voltage conversion circuit of MRI pattern that the embodiment of the present invention uses
Control circuit.
The workflow diagram of the pulse generator of the lesions located in deep brain device that Fig. 9 provides for the embodiment of the present invention 1.
The further workflow of the pulse generator of the lesions located in deep brain device that Figure 10 provides for the embodiment of the present invention 1
Figure.
The workflow diagram of the peripheral control unit of the lesions located in deep brain device that Figure 11 provides for the embodiment of the present invention 1.
The workflow diagram of the pulse generator of the lesions located in deep brain device that Figure 12 provides for the embodiment of the present invention 2.
The workflow diagram of the pulse generator of the lesions located in deep brain device that Figure 13 provides for the embodiment of the present invention 3.
The workflow diagram of the pulse generator of the lesions located in deep brain device that Figure 14 provides for the embodiment of the present invention 4.
Main element symbol description
Lesions located in deep brain device 10
Outside program control instrument 11
Pulse generator 12
Extension lead 14
Stimulating electrode 16
Electrode contacts 18
Power module 100
Manostat 101
DC-DC voltage conversion circuit 102
Communication module 103
Magnetic field sensor 104
Control circuit 105
Battery 1001
Current-limiting resistance RS 1002
A/D 1003
Judge module 1004
Magnetic field induction element 1005
Specific examples below will further illustrate the present invention in conjunction with above-mentioned accompanying drawing.
Detailed description of the invention
The invention provides a kind of implantable medical devices and control method thereof.Wherein this implantable medical devices can be
Cardiac pacemaker, defibrillator, lesions located in deep brain device, spinal stimulator, vagus nerve stimulator, the intestines and stomach stimulator or other
Similar implantable medical devices.The present invention only illustrates as a example by lesions located in deep brain device, enters the present invention in conjunction with accompanying drawing
One step explanation.
Referring to Fig. 1, described lesions located in deep brain device 10 includes: an outside program control instrument 11 and the pulse implanted are sent out
Raw device 12, extension lead 14 and stimulating electrode 16 form.Described outside program control instrument 11 controls this pulse generator 12 for producing
The electric pulse of certain pattern, passes at the electrode contacts 18 of stimulating electrode 16 by this extension lead 14, by this electrode contacts
18 stimulate particular core group can reach to treat the purpose of disease.
Referring to Fig. 2, described pulse generator 12 is internal to be included: a power module 100, manostat 101, DC-DC voltage
Translation circuit 102, control circuit 105, magnetic field sensor 104, and communication module 103 etc..Described power module 100 passes through institute
State manostat 101 and produce constant voltage, as the input voltage of described DC-DC voltage conversion circuit 102.Described control circuit
105 for controlling in DC-DC voltage conversion circuit 102 energy storage of inductance and releasing energy.Outside described magnetic field sensor 104 is used for detecting
The strong magnetic field circumstance in portion, and adjust control circuit 105 according to the result of feedback.Described communication module 103 is used for and described outside
Communication between program control instrument 11.
The structure of described magnetic field sensor 104 does not limits.Referring to Fig. 3, described magnetic field sensor 104 generally includes magnetic field sense
Answer element 1005 and the judge module 1004 electrically connected with this magnetic field induction element 1005.Described judge module 1004 is according to this
The detection data of magnetic field induction element 1005, it may be judged whether there is strong external magnetic field, i.e. whether exist and can make described DC-DC
The magnetic field that energy storage inductor in voltage conversion circuit 102 is saturated.The strong magnetic in outside that this magnetic field induction element 1005 can be special
Field sensing element, such as hall effect sensor, it is also possible to be the inspection of a detection described pulse generator 12 internal circuit parameter
Survey element, by the existence of the change presumption strong external magnetic field of described pulse generator 12 internal circuit parameter.Described judgement mould
Block 1004 can be single judge module, it is also possible to be described pulse generator 12 central control module (not shown) one
Part.If described judge module 1004 is single judge module, then require connect to central control module.
Referring to Fig. 4, in the present embodiment, described power module 100 includes: battery 1001, current-limiting resistance RS1002 and
A/D1003.Described current-limiting resistance RS1002 for limiting the output electric current of this battery 1001, thus protects battery 1001.Described
A/D1003 is used for monitoring current-limiting resistance RSThe voltage at 1002 two ends, thus monitor voltage and the output electric current of battery 1001 in real time,
Thus monitor the duty of battery 1001.Described magnetic field sensor 104 includes: current-limiting resistance RS1002, A/D1003 and with
The judge module 1004 that this A/D1003 connects.Described judge module 1004 is according to the described A/D1003 monitoring number to battery 1001
According to, it may be judged whether there is strong external magnetic field.
Be appreciated that under strong magnetic environment, the energy storage inductor in described DC-DC voltage conversion circuit 102 due to saturated and
Cause inductance value to decline, thus the electric current flowing through inductance increases.Owing to inductive current comes from the output electricity of described battery 1001
Stream, the increase of described inductive current will necessarily cause the increase of the output electric current of described battery 1001.Therefore, by described battery
The actual output current of 1001 and the described battery 1001 saturated shape of energy storage inductor in described DC-DC voltage conversion circuit 102
Electric current under state contrasts, it is possible to judge whether strong external magnetic field.The magnetic field sensor 104 of the embodiment of the present invention leads to
Cross monitoring battery 1001 electric current and achieve that the function of magnetic field sensor, it is not necessary to extra magnetic induction components and parts.
It is appreciated that described magnetic field sensor 104 can work always, it is also possible to start under the control of peripheral control unit
Work or power cut-off.Such as, described magnetic field sensor 104 can start after the detection receiving peripheral control unit instructs
Work, in power cut-off after the stopping detection instruction receiving described outside program control instrument 11.Described peripheral control unit can be
Outside program control instrument 11 or other control equipment being connected with pulse generator 12 such as computer, mobile phone.In the present embodiment, this peripheral hardware control
Device processed is outside program control instrument 11.
Described pulse generator 12 has MRI pattern and two kinds of mode of operations of normal mode.Described pulse generator 12 can
With the strong external magnetic field information detected according to described magnetic field sensor 104 or according to receive from peripheral control unit
The instruction mutual switching between MRI pattern and normal mode, and record relevant handover information.Described pulse introduced below is sent out
The MRI pattern of raw device 12 and the difference of normal mode and switching mode.
Referring to Fig. 5, as a example by DC-DC Boost circuit, described DC-DC voltage conversion circuit 102 includes: energy storage inductor
L, inductance equivalent series resistance RL, switching tube M1, sustained diode 1, and filter capacitor Cload.Under normal circumstances, in order to carry
The efficiency of high DC-DC voltage conversion circuit 102, energy storage inductor L is usually core inductance.Under MRI, magnetic core is saturated, causes storage
Can inductance inductance value L be that the order of magnitude declines, thus cause other parameter change of circuit, most typical cause inductive current exactly
Increase at double.
Referring to Fig. 6, inductive current is at normal work and comparing result when working under 3T nuclear-magnetism high-intensity magnetic field, wherein,
inormalT () represents real-time current during normal work, ipnormalRepresent current peak during normal work, imriT () represents MRI
Real-time current when working under high-intensity magnetic field, ipmriRepresent current peak when working under MRI high-intensity magnetic field.It will be appreciated from fig. 6 that normal work
When making, the inductance value in DC-DC voltage conversion circuit 102 keeps normal value, inductive current peak ipnormalLess.At 3T nuclear-magnetism
Under, due to the saturation effect of magnetic core, core inductance is close to hollow inductance, and inductance value is that the order of magnitude declines.The inductance value reduced,
Cause inductive current peak ipmriBigger.On the one hand circuit may be caused damage by the increase of inductive current, on the other hand causes
The power consumption of circuit increases, and causes the efficiency of circuit to reduce.
Now as a example by DC-DC Boost circuit, and assume that circuit works in discontinuous mode (DCM), strong at MRI
Under magnetic field, it is assumed that inductance value reduces N times, discounting for coil equivalent series circuit, the various resistance such as switch conduction resistance
Impact, inductive current peak will increase N times.So, under MRI high-intensity magnetic field, the power consumption of DC-DC circuit significantly increases.It addition, it is electric
The root-mean-square value of inducing current is expressed as follows:
Wherein, IL,RMSRepresent inductive current root-mean-square value, Vo, IoRepresenting output voltage and electric current respectively, M represents output electricity
Pressure and the ratio of input voltage, L represents inductance value, fsRepresent switch regulation and control frequency.
Under MRI pattern, it is assumed that other parameter constant in formula (1), inductance value L diminishes N times,
IL, RMS_MRI=N1/4IL, RMS_NMRI (2)
It is to say, under MRI high-intensity magnetic field, inductive current root-mean-square value when the root-mean-square value of inductive current is normally to work
N1/4Times.
In Boost circuit, owing to power supply is connected all the time with inductance, inductive current is consistent with electric power outputting current.Therefore,
Formula (2) means the N under MRI high-intensity magnetic field, when the power consumption of DC-DC voltage conversion circuit 102 is normally to work simultaneously1/4Times.Change sentence
Talking about, work 1 hour under MRI high-intensity magnetic field, be equivalent to normally work N1/4Hour, say, that under MRI high-intensity magnetic field with just
The efficiency worked in the case of Chang is than for N1/4:1。。
Therefore, under MRI high-intensity magnetic field, the hidden danger that DC-DC on-off circuit 102 exists is mainly by the electricity increased exponentially
Inducing current causes, to this end, can improve the DC-DC voltage conversion circuit 102 under MRI high-intensity magnetic field.Send out for introduced below
Bright how under MRI high-intensity magnetic field, DC-DC voltage conversion circuit 102 to be improved, thus realize MRI pattern.
Refer to Fig. 7, for the feedback control circuit of the DC-DC voltage conversion circuit 102 that the present invention uses.Described DC-DC
The output voltage of voltage conversion circuit 102 is through divider resistance Rf1And Rf2The feedback voltage V obtained after dividing potential dropfbWith expection with reference to electricity
Pressure VrefCompare, obtain error signal, this error signal and control pulse 201 co-controlling DC-DC voltage conversion circuit
The conducting of 102 breaker in middle and disconnection.
Described control pulse 201 generally includes frequency and two parameters of dutycycle, in order to adapt to circuit ginseng under MRI high-intensity magnetic field
The change that number occurs, improves to this end, this can be controlled pulse 201.As, shown in Fig. 8, when normally working, control pulse
201 first clock generation circuit 301 is produced when can use controls frequency fs1, when the generation of this clock signal is by external low frequency
Zhong Yuan provides.Under MRI high-intensity magnetic field, control pulse 201 and frequency produced by second clock generation circuit 302 can be used higher
fs2Being controlled, this clock signal is provided by the internal clocking DCO of microcontroller.The benefit of this way is, circuit need not increase
Add the f under extra device, normal mode of operations1External clock reference can be used to provide, the f under MRI high-intensity magnetic fields2Can use micro-
The digital dock carried inside controller, the highest frequency of this clock all in 10MHz magnitude, can simply be carried out by software
Frequency regulates and controls.Additionally, except by changing the control frequency controlling pulse 201, it is possible to change its dutycycle, or change simultaneously
Control frequency and dutycycle.So, the conversion of normal mode and MRI pattern can just be realized.
Different embodiment is below divided to introduce the method for work of described lesions located in deep brain device 10.
Embodiment 1
See Fig. 9, in embodiment 1, the outside that described pulse generator 12 detects according to described magnetic field sensor 104
The mutual switching that high-intensity magnetic field information is automatically obtained between MRI pattern and normal mode.Described magnetic field sensor 104 is constantly in work
Make state.Specifically, the workflow of the pulse generator 12 of described lesions located in deep brain device 10 comprises the following steps:
Step S11, detection strong external magnetic field also judges whether to detect the existence of strong external magnetic field, if it is, enter step
Rapid S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of pulse generator 12 of strong external magnetic field, and labelling is in high-intensity magnetic field
Environment, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step
S14；
Step S15, the time of record strong external magnetic field disappearance and the state of pulse generator 12, labelling leaves high-intensity magnetic field ring
Border, and enter step S16；
Step S16, switches to normal mode, labelling MRI mode switching event, and returns step S11.
It is appreciated that above-mentioned method of work usually occurs in patient and enters MRI sensing chamber, in MRI sensing chamber, carries out MRI
During detecting and leaving MRI sensing chamber.
With further reference to Figure 10, in embodiment 1, after patient leaves MRI sensing chamber (after i.e. strong external magnetic field disappears),
The workflow of the pulse generator 12 of described lesions located in deep brain device 10 can also comprise the following steps:
Step S17, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S18, if it does not,
Continue to repeat step S17；
Step S18, it may be judged whether have MRI mode switching event, if it is, enter step S19, if it is not, then enter step
Rapid S22；
Step S19, sends MRI mode switching event relevant information to peripheral control unit, subsequently into step S20；
Step S20, waits the response of peripheral control unit, and enters step S21；
Step S21, resets MRI mode switching event labelling, and enters step S22；
Step S22, terminates.
With further reference to Figure 11, in embodiment 1, after patient leaves MRI sensing chamber (after i.e. strong external magnetic field disappears),
The workflow of the peripheral control unit of described lesions located in deep brain device 10 comprises the following steps:
Step S23, sends inquiry instruction to pulse generator 12, and enters step S24；
Step S24, it may be judged whether receive the prompting of MRI mode switching event, if it is, enter step S25, if it does not,
Enter step S29；
Step S25, receives MRI mode switching event relevant information, subsequently into step S26；
Step S26, display MRI mode switching event prompting warning, subsequently into step S27；
Step S27, waits that user checks, and enters step S28；
Step S28, sends response to pulse generator 12, and enters step S29；
Step S29, terminates.
Further, described step S25 can also include: according to the battery current that monitors calculate under MRI high-intensity magnetic field with just
Often efficiency ratio during work.Described step S26 can also include: this efficiency ratio is shown to user.
Embodiment 2
Seeing Figure 12, in example 2, the workflow of the pulse generator 12 of described lesions located in deep brain device 10 includes
Following steps:
Step S10, it may be judged whether receive the detection instruction of peripheral control unit, if it is, enter step S11, if it does not,
Continue to repeat step S10；
Step S11, starts detect strong external magnetic field and judge whether to detect the existence of strong external magnetic field, if it is, enter
Enter step S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of pulse generator 12 of strong external magnetic field, and labelling is in high-intensity magnetic field
Environment, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step
S14；
Step S15, the time of record strong external magnetic field disappearance and the state of pulse generator 12, labelling leaves high-intensity magnetic field ring
Border, and enter step S16；
Step S16, switches to normal mode, labelling MRI mode switching event, and enters step S17；
Step S17, stops detection strong external magnetic field, and returns step S10.
In the embodiment of the present invention 2, described magnetic field sensor 104 is started working under peripheral control unit control or terminates work
Make.In the embodiment of the present invention 2, the method for work of the pulse generator 12 of described lesions located in deep brain device 10 and the embodiment of the present invention
In 1, the method for work of pulse generator 12 is essentially identical, and its difference is, includes that one judges whether to receive before step S11
Step S10 of the detection instruction of peripheral control unit；And be not to return step S11 after step S16, but enter step S17.
Further, described step S17 can specifically include:
Step S171, it may be judged whether receive the stopping detection instruction of peripheral control unit, if it is, enter step S173,
If it does not, enter step S172；
Step S172, if more than a time threshold, if it is, enter step S173, if it does not, return step S171；
Step S173, stops detection strong external magnetic field.
It is appreciated that in the embodiment of the present invention 2, it is also possible to include the method for work described in above-mentioned Figure 10 and Figure 11.
Embodiment 3
Seeing Figure 13, in embodiment 3, the workflow of the pulse generator 12 of described lesions located in deep brain device 10 includes
Following steps:
Step S10, it may be judged whether receive peripheral control unit switches to MRI mode instruction, if it is, enter step
S11, if it does not, continue to repeat step S10；
Step S11, switches to MRI pattern, and enters step S12；
Step S12, it may be judged whether the normal mode that switches to receiving peripheral control unit instructs, if it is, enter step
S15, if it does not, enter step S13；
Step S13, it may be judged whether overtime threshold value, if it is, enter step S14, if it does not, return step S12；
Step S14, switches to normal mode, record time-out handover event, and enters step S15；
Step S15, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S16, if it does not, enter
Enter step S17；
Step S16, sends time-out handover event information to peripheral control unit, enters step S17；
Step S17, terminates.
In the embodiment of the present invention 3, manually switching realize the MRI pattern of described pulse generator 12 and normal mode it
Between switching.And above-described embodiment 1 and 2 all realizes MRI pattern and the normal mode of described pulse generator 12 by automatic switchover
Switching between formula.
In described step S13, this time threshold is an empirical value, and usually patient enters MRI sensing chamber, detects at MRI
Indoor carry out MRI detection and leave the time required for MRI sensing chamber.
Being appreciated that in the embodiment of the present invention 3, step S15 and S16 are optional step.
Embodiment 4
Seeing Figure 14, in example 4, the workflow of the pulse generator 12 of described lesions located in deep brain device 10 includes
Following steps:
Step S10, it may be judged whether receive peripheral control unit switches to MRI mode instruction, if it is, enter step
S11, if it does not, continue to repeat step S10；
Step S11, switches to MRI pattern, and enters step S12；
Step S12, starts detect strong external magnetic field and judge whether to detect the existence of strong external magnetic field, if it is, enter
Enter step S13, if it does not, continue to repeat step S12；
Step S13, record detects time and the state of pulse generator 12 of strong external magnetic field, and labelling is in high-intensity magnetic field
Environment, and enter step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step
S14；
Step S15, the time of record strong external magnetic field disappearance and the state of pulse generator 12, labelling leaves high-intensity magnetic field ring
Border, and enter step S16；
Step S16, it may be judged whether the normal mode that switches to receiving peripheral control unit instructs, if it is, enter step
S18, if it does not, enter step S17；
Step S17, it may be judged whether overtime threshold value, if it is, enter step S18, if it does not, return step S16；
Step S18, stops detection strong external magnetic field, switches to normal mode, record time-out handover event, and enters step
S19；
Step S19, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S20, if it does not, enter
Enter step S21；
Step S20, sends time-out handover event information to peripheral control unit, enters step S21；
Step S21, terminates.
In the embodiment of the present invention 4, described magnetic field sensor 104 is after MRI pattern opened by described pulse generator 12, certainly
Move and start working, and power cut-off automatically after strong external magnetic field disappearance being detected.In the embodiment of the present invention 4, described brain deep
The method of work of the pulse generator 12 of electrostimulator 10 is basic with the method for work of pulse generator 12 in the embodiment of the present invention 3
Identical, its difference is, adds described magnetic field sensor 104 and detects the step of strong external magnetic field, and outside detecting
Portion's high-intensity magnetic field information and the described pulse generator 12 duty under this strong external magnetic field carry out the step recorded.
It is appreciated that in the embodiment of the present invention 4, it is also possible to include the method for work described in above-mentioned Figure 10 and Figure 11.
It is given above multiple embodiments of the present invention, it is to be understood that without departing from present disclosure essence
In the case of god and scope, can make a variety of changes, replace and change, these embodiments are also the guarantor of the present invention
In the range of protecting.
Claims (10)
1. having a method of work for the implantable medical devices of MRI pattern, this implantable medical devices includes et al. Ke
Device and peripheral control unit, and this et al. Ke device includes the component sensitive to strong external magnetic field；This implantable medical
The method that the method for work of apparatus includes controlling this et al. Ke device；It is characterized in that, this et al. Ke device of this control
Method comprises the following steps:
Step S11, detection strong external magnetic field also judges whether to detect the existence of strong external magnetic field, if it is, enter step
S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of et al. Ke device of strong external magnetic field, and labelling is in high-intensity magnetic field ring
Border, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step S14；
Step S15, the time of record strong external magnetic field disappearance and the state of et al. Ke device, labelling leaves strong magnetic field circumstance,
And enter step S16；And
Step S16, switches to normal mode, labelling MRI mode switching event, and returns step S11.
The method of work of the implantable medical devices with MRI pattern the most according to claim 1, it is characterised in that described control
The method of et al. Ke device processed further includes steps of
Step S17, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S18, if it does not, continue
Repeat step S17；
Step S18, it may be judged whether have MRI mode switching event, if it is, enter step S19, if it is not, then enter step
S22；
Step S19, sends MRI mode switching event relevant information to peripheral control unit, subsequently into step S20；
Step S20, waits the response of peripheral control unit, and enters step S21；
Step S21, resets MRI mode switching event labelling, and enters step S22；And step S22, terminate.
The method of work of the implantable medical devices with MRI pattern the most according to claim 2, it is characterised in that this implantation
The method that the method for work of formula medical apparatus and instruments also includes controlling this peripheral control unit；The method of this control peripheral control unit include with
Lower step:
Step S23, sends inquiry instruction to et al. Ke device, and enters step S24；
Step S24, it may be judged whether receive the prompting of MRI mode switching event, if it is, enter step S25, if it does not, enter
Step S29；
Step S25, receives MRI mode switching event relevant information, subsequently into step S26；
Step S26, display MRI mode switching event prompting warning, subsequently into step S27；
Step S27, waits that user checks, and enters step S28；
Step S28, sends response to et al. Ke device, and enters step S29；And
Step S29, terminates.
4. having a method of work for the implantable medical devices of MRI pattern, this implantable medical devices includes one interplantation
Enter device and a peripheral control unit, and this et al. Ke device includes the component sensitive to strong external magnetic field；This implanted
The method that the method for work of medical apparatus and instruments includes controlling this et al. Ke device；It is characterized in that, this et al. Ke of this control fills
The method put comprises the following steps:
Step S10, it may be judged whether receive the detection instruction of peripheral control unit, if it is, enter step S11, if it does not, continue
Repeat step S10；
Step S11, starts detect strong external magnetic field and judge whether to detect the existence of strong external magnetic field, if it is, enter step
Rapid S12, if it does not, continue to repeat step S11；
Step S12, record detects time and the state of et al. Ke device of strong external magnetic field, and labelling is in high-intensity magnetic field ring
Border, and enter step S13；
Step S13, switches to MRI pattern, labelling MRI mode switching event, and enters step S14；
Step S14, it is judged that whether strong external magnetic field disappears, if it is, enter step S15, if it is not, then repeat step S14；
Step S15, the time of record strong external magnetic field disappearance and the state of et al. Ke device, labelling leaves strong magnetic field circumstance,
And enter step S16；
Step S16, switches to normal mode, labelling MRI mode switching event, and enters step S17；And
Step S17, stops detection strong external magnetic field, and returns step S10.
The method of work of the implantable medical devices with MRI pattern the most according to claim 4, it is characterised in that described step
In rapid S17, the described method stopping detection strong external magnetic field comprises the following steps:
Step S171, it may be judged whether receive the stopping detection instruction of peripheral control unit, if it is, enter step S173, if
No, enter step S172；
Step S172, if more than a time threshold, if it is, enter step S173, if it does not, return step S171；And
Step S173, stops detection strong external magnetic field.
The method of work of the implantable medical devices with MRI pattern the most according to claim 4, it is characterised in that described control
The method of et al. Ke device processed further includes steps of
Step S17A, it may be judged whether receive the inquiry instruction of peripheral control unit, if it is, enter step S18, if it does not, continue
Continuous repetition step S17A；
Step S18, it may be judged whether have MRI mode switching event, if it is, enter step S19, if it is not, then enter step
S22；
Step S19, sends MRI mode switching event relevant information to peripheral control unit, subsequently into step S20；
Step S20, waits the response of peripheral control unit, and enters step S21；
Step S21, resets MRI mode switching event labelling, and enters step S22；And
Step S22, terminates.
The method of work of the implantable medical devices with MRI pattern the most according to claim 6, it is characterised in that this implantation
The method that the method for work of formula medical apparatus and instruments also includes controlling this peripheral control unit；The method of this control peripheral control unit include with
Lower step:
Step S23, sends inquiry instruction to et al. Ke device, and enters step S24；
Step S24, it may be judged whether receive the prompting of MRI mode switching event, if it is, enter step S25, if it does not, enter
Step S29；
Step S25, receives MRI mode switching event relevant information, subsequently into step S26；
Step S26, display MRI mode switching event prompting warning, subsequently into step S27；
Step S27, waits that user checks, and enters step S28；
Step S28, sends response to et al. Ke device, and enters step S29；And
Step S29, terminates.
8. there is an implantable medical devices for MRI pattern, comprising: peripheral control unit and et al. Ke device；Described
Include inside et al. Ke device: power module, manostat, DC-DC voltage conversion circuit, control circuit, magnetic field sensor with
And communication module, it is characterised in that the method for work of described implantable medical devices is for such as claim 1 to 7 any one institute
The method of work of the implantable medical devices stated.
The implantable medical devices with MRI pattern the most according to claim 8, it is characterised in that described magnetic field sensor bag
Include magnetic field induction element and the judge module electrically connected with this magnetic field induction element；Described judge module is according to this magnetic field induction
The detection data of element, it may be judged whether there is the magnetic field that the energy storage inductor in described DC-DC voltage conversion circuit can be made saturated.
The implantable medical devices with MRI pattern the most according to claim 8, it is characterised in that described magnetic field induction element
For hall effect sensor；Or the internal electricity of pulse generator that described magnetic field induction element is a detection described et al. Ke device
The detecting element of LUSHEN number, by the existence of the change presumption strong external magnetic field of described pulse generator internal circuit parameter.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110160806A1 (en) * | 2009-12-30 | 2011-06-30 | Lyden Michael J | Implantable medical device switching power supply including multiple modes |
| CN103517733A (en) * | 2011-04-27 | 2014-01-15 | 美敦力公司 | Pacing in the presence of electromagnetic interference |
| US20140018870A1 (en) * | 2004-12-17 | 2014-01-16 | Cardiac Pacemakers, Inc. | Mri operation modes for implantable medical devices |
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2016
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140018870A1 (en) * | 2004-12-17 | 2014-01-16 | Cardiac Pacemakers, Inc. | Mri operation modes for implantable medical devices |
| US20110160806A1 (en) * | 2009-12-30 | 2011-06-30 | Lyden Michael J | Implantable medical device switching power supply including multiple modes |
| CN103517733A (en) * | 2011-04-27 | 2014-01-15 | 美敦力公司 | Pacing in the presence of electromagnetic interference |
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