CN204485064U - A kind of implantable nerve stimulating system - Google Patents
A kind of implantable nerve stimulating system Download PDFInfo
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- CN204485064U CN204485064U CN201520145741.9U CN201520145741U CN204485064U CN 204485064 U CN204485064 U CN 204485064U CN 201520145741 U CN201520145741 U CN 201520145741U CN 204485064 U CN204485064 U CN 204485064U
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Abstract
This utility model relates to a kind of implantable nerve stimulating system, and it comprises: a pulse generator, a stimulating electrode, and a vitro program controlled instrument; It is characterized in that, described pulse generator comprises: a power module, one control module, one capacitive detection module be electrically connected with this control module, one channel selecting module be electrically connected with this control module, a signal acquisition module be electrically connected with this control module, a wireless communication module be electrically connected with this control module, one forward stimulates electric capacity, and a negative sense stimulates electric capacity and a shell.Implantable nerve stimulating system of the present utility model provides multichannel pulse output function, based on the active charge balancing function of capacitor charge and discharge, has active charge balancing function.
Description
Technical field
This utility model belongs to mini-medical instrument field, the implantable nerve stimulating system of particularly a kind of medical treatment use and its method of work.
Background technology
Implantable nerve stimulating system kind is a lot, as implanted brain depth stimulator, implanted spinal stimulator, implanted vagus nerve stimulator etc.Produce pulse by the stimulation output module of implantable nerve stimulating system, discharge high-frequency electrical stimulation by implant electrode, stimulate the nerve of specific part in body, thus realize the therapeutical effect to specified disease.
Due to implantable nerve stimulating system use time, the direct implant into body organization internal of its stimulating electrode.Therefore, this kind equipment is directly connected to the safety of implantation person, needs the human nerve tissue to it directly stimulates to realize strict charge balance.
Current implantable nerve stimulating system, strict charge balance realizes mainly through the mode of passive charge balance, can realize the safety of implantable nerve stimulating system.But the mode of passive charge balance makes more, the passive charge balanced time of sheet external component in system longer, and passive charge balance process waveforms amplitude is uncontrollable, controls also underaction.In addition, the current implantable nerve stimulating system possessing active charge balancing function, there is again the problems such as efficiency is low, charge balance safety is not enough in its electricity usage scheme.
Utility model content
In view of this, necessaryly provide a kind of efficiency high and the implantable nerve stimulating system that charge balance safety is high and method of work thereof.
A kind of implantable nerve stimulating system, it comprises: a pulse generator, a stimulating electrode, and a vitro program controlled instrument; It is characterized in that, described pulse generator comprises:
One power module, this power module comprises a positive voltage output end and a negative voltage outfan;
One control module, this control module comprises a microcontroller, a DA output module and a comparator;
One channel selecting module be electrically connected with this control module, this channel selecting module is used for the contact array of this pulse generator with described stimulating electrode to be electrically connected;
One forward stimulates electric capacity and a negative sense to stimulate electric capacity, and described forward stimulates electric capacity to stimulate the capacitance of electric capacity consistent with described negative sense, and described forward stimulates electric capacity and described negative sense to stimulate electric capacity ground connection respectively;
Described positive current outfan stimulates electric capacity to be electrically connected by first switch controlled by this control module with described forward, for stimulating capacitor charging for described forward; Described negative voltage outfan stimulates electric capacity to be electrically connected by the 3rd switch that is controlled by this control module with described negative sense, for stimulating capacitor charging for described negative sense;
Described forward stimulates electric capacity to be electrically connected with described channel selecting module by a second switch controlled by this control module, for providing forward stimulation voltage to described channel selecting module; Described negative sense stimulates electric capacity to be electrically connected with described channel selecting module, for providing negative sense stimulation voltage to described channel selecting module by the 4th switch that is controlled by this control module;
One capacitive detection module be electrically connected with this control module, this capacitive detection module comprises the positive current outfan and a negative current outfan stimulating electric capacity to be electrically connected with this negative sense that a timer, stimulates electric capacity to be electrically connected with this forward, and this capacitive detection module stimulates electric capacity and described negative sense to stimulate the capacitance of electric capacity for detecting described forward;
One signal acquisition module be electrically connected with this control module, and this signal acquisition module stimulates electric capacity and described negative sense to stimulate electric capacity to be electrically connected respectively with described forward, stimulate electric capacity and negative sense to stimulate the magnitude of voltage of electric capacity for gathering described forward;
One wireless communication module be electrically connected with this control module; And
One shell, this shell is for accommodating above-mentioned module.
Compared with prior art, implantable nerve stimulating system of the present utility model provides multichannel pulse output function, based on the active charge balancing function of capacitor charge and discharge, has active charge balancing function.And the active charge balancing function of this implantable nerve stimulating system possesses high-precision characteristic, greatly reduces neural tissue injury, substantially increases the safety of system, realize high-precision means cost in power consumption extremely low simultaneously.
Accompanying drawing explanation
The structural representation of the implantable nerve stimulating system that Fig. 1 provides for this utility model embodiment.
Fig. 2 is the circuit block diagram of the pulse generator of the implantable nerve stimulating system of Fig. 1.
The method of work flow chart of the pulse generator of the implantable nerve stimulating system that Fig. 3 provides for this utility model embodiment.
The method of work flow chart of the pulse generator of the implantable nerve stimulating system that Fig. 4-7 provides for another embodiment of this utility model, wherein eliminates part run in Fig. 4-7.
The method flow diagram of the Detection capacitance value of the implantable nerve stimulating system that Fig. 8 provides for this utility model embodiment.
Main element symbol description
| Implanted lesions located in deep brain device | 10 | Pulse generator | 11 |
| Control module | 110 | Microcontroller | 1101 |
| DA output module | 1102 | Comparator | 1103 |
| Shell | 111 | Power module | 112 |
| Negative voltage outfan | 1121 | Positive voltage output end | 1122 |
| Capacitive detection module | 113 | Positive direct-current outfan | 1131 |
| Negative DC output end | 1132 | Timer | 1133 |
| Channel selecting module | 114 | Signal acquisition module | 115 |
| Wireless communication module | 116 | Forward stimulates electric capacity | 117 |
| Negative sense stimulates electric capacity | 118 | Switch | 1190 |
| Switch | 1191 | Switch | 1192 |
| Switch | 1193 | Switch | 1194 |
| Switch | 1195 | Switch | 1196 |
| Stimulating electrode | 12 | Contact array | 120 |
| Extension lead | 13 | Vitro program controlled instrument | 14 |
Following detailed description of the invention will further illustrate this utility model in conjunction with above-mentioned accompanying drawing.
Detailed description of the invention
Below in conjunction with the accompanying drawings and the specific embodiments, the implantable nerve stimulating system provided this utility model and method of work thereof are set forth.
Be appreciated that the implantable nerve stimulating system that this utility model provides can be implanted brain depth stimulator, implanted spinal stimulator, implanted vagus nerve stimulator.This utility model embodiment is only described for implanted lesions located in deep brain device.
Refer to Fig. 1, this utility model embodiment provides an implanted lesions located in deep brain device 10, it comprises: one implants subcutaneous pulse generator 11, the stimulating electrode 12 of the one dark brain position of implantation, one extension lead 13 connecting this stimulating electrode 12 and pulse generator 11, and one for the vitro program controlled instrument 14 of this pulse generator 11 program control.
Described pulse generator 11 produces specific electric stimulation pulse signal, and carries out stimulation regulation and control by described extension lead 13 and stimulating electrode 12 conducting to stimulation location.Described vitro program controlled instrument 14 can with the wireless connections of described pulse generator 11, and change its electric pulse stimulation parameter.
Please with further reference to Fig. 2, described stimulating electrode 12 tip has a contact array 120, and it comprises multiple contact, is labeled as contact 1 respectively, contact 2 ... and contact N.After stimulating electrode 12 is implanted target position, have at least a contact to contact closely with stimulation target spot, so that suitable electricity irritation is conducted to target spot, treat the disease of neural class.Be appreciated that the number of described stimulating electrode 12 is not limited to one, can select as required, corresponding position is stimulated, to ensure effect of stimulation.
Be appreciated that described extension lead 13 is a selectable unit, described stimulating electrode 12 can be directly connected on this pulse generator 11.Only have when the distance after described stimulating electrode 12 implants with this pulse generator 11 is larger, just need to be connected by extension lead 13.
Refer to Fig. 2, the circuit of described pulse generator 11 comprises: control module 110, shell 111, power module 112, capacitive detection module 113, channel selecting module 114, signal acquisition module 115, wireless communication module 116, forward stimulates electric capacity 117 and a negative sense to stimulate electric capacity 118.Described control module 110, power module 112, capacitive detection module 113, channel selecting module 114, signal acquisition module 115, wireless communication module 116, forward stimulate electric capacity 117 and negative sense to stimulate electric capacity 118 to be all contained in this shell 111.
Described control module 110 controls modules and the element co-ordination of whole pulse generator 11.Described control module 110 comprises: microcontroller 1101, DA (Digital to Analog) output module 1102 and a comparator 1103.Wherein, described microcontroller 1101, is interconnected between described DA output module 1102 and described comparator 1103.Corresponding analog quantity can be exported by the digital output access DA output module 1102 of microcontroller 1101, and by this analog quantity access comparator 1103 to set the comparative voltage of comparator 1103, and the Output rusults of real-time output comparator 1103.
Described power module 112 comprises battery and electric power management circuit.Described power module 112 can under battery powered more than through electric power management circuit management after produce the positive and negative out-put supply of direct current, one monocell is powered the lower positive and negative out-put supply of direct current produced after electric power management circuit management, and one is placed in alternating electromagnetic field to obtain one or more of the alternating current power supply of energy by electromagnetic induction principle.Described power module 112 comprises positive voltage output end 1122 and a negative voltage outfan 1121.Described power module 112 is electrically connected with described control module 110 and capacitive detection module 113, for this control module 110 and capacitive detection module 113 are powered.Be appreciated that described power module 112 is also electrically connected with described channel selecting module 114, signal acquisition module 115 and wireless communication module 116, and be respectively its power supply (not shown).
Described capacitive detection module 113 comprises the negative DC output end 1132 of a positive direct-current outfan 1131, and a timer 1133.Described positive direct-current outfan 1131, negative DC output end 1132, timer 1133 is electrically connected with described microcontroller 1101 respectively, is controlled by this microcontroller 1101.Described positive direct-current outfan 1131 stimulates electric capacity 117 and signal acquisition module 115 to be electrically connected respectively with described forward.Described negative DC output end 1132 stimulates electric capacity 118 and signal acquisition module 115 to be electrically connected respectively with described negative sense.
Described forward stimulates electric capacity 117 to stimulate the capacitance of electric capacity 118 consistent with described negative sense.Described forward stimulates electric capacity 117 one end ground connection, and the other end is electrically connected with described positive voltage output end 1122, described positive direct-current outfan 1131, described signal acquisition module 115 and described channel selecting module 114 respectively.Described positive voltage output end 1122 and described forward stimulate between electric capacity 117 and arrange a switch 1190, and described channel selecting module 114 and described forward stimulate between electric capacity 117 and arrange a switch 1194.Further, described forward stimulates the other end of electric capacity 117 also by switch 1192 ground connection.
Described negative sense stimulates electric capacity 118 one end ground connection, and the other end is electrically connected with described negative voltage outfan 1121, described negative DC output end 1132, described signal acquisition module 115 and described channel selecting module 114 respectively.Described negative voltage outfan 1121 and described negative sense stimulate between electric capacity 118 and arrange a switch 1191, and described channel selecting module 114 and described negative sense stimulate between electric capacity 118 and arrange a switch 1195.Further, described negative sense stimulates the other end of electric capacity 118 also by switch 1193 ground connection.Further, it is the first wire with the wire of described channel selecting module 114 that definition herein connects described switch 1194, and it is the second wire with the wire of described channel selecting module 114 that definition connects described switch 1195.One switch 1196 is set between described first wire and the second wire.Described switch 1190, switch 1191, switch 1192, switch 1193, switch 1194, switch 1195 and switch 1196 are electrically connected with described microcontroller 1101 respectively, are controlled by this microcontroller 1101.
Described channel selecting module 114 is electrically connected with described microcontroller 1101, contact array 120 and shell 111 respectively.Described channel selecting module 114 can be selected some by what stimulate electric capacity 117 and negative sense to stimulate the energy delivery of electric capacity 118 in contact array 120 and shell 111 from described forward, carries out electric pulse stimulation to tissue.Further, described channel selecting module 114 is ground connection also, and possess the function by contact array 120 and shell 111 ground connection.
Described signal acquisition module 115 is electrically connected with described microcontroller 1101, and stimulates electric capacity 117 and negative sense to stimulate the magnitude of voltage of electric capacity 118 for gathering described forward.Described wireless communication module 116 is electrically connected with described microcontroller 1101, and for described vitro program controlled instrument 14 radio communication.Described wireless communication module 116 specifically comprises a radio communication circuit and a radio antenna.
Described shell 111 is a biocompatible metal shell, can use when electricity irritation as an electrode contacts.In the present embodiment, described shell 111 is a titanium shell.
Be appreciated that, described pulse generator 11 is except the battery in shell 111, power module 112, the radio antenna in wireless communication module 116, forward stimulation electric capacity 117 and negative sense stimulation electric capacity 118, and the radio communication circuit in the electric power management circuit in its control module 110, power module 112, capacitive detection module 113, channel selecting module 114, signal acquisition module 115, wireless communication module 116 can be integrated on same chip.Therefore, this pulse generator 11 volume is little, is applicable to the characteristic that implantable medical device volume is limited.
Described vitro program controlled instrument 14 is undertaken by the modes such as display screen, display lamp, buzzer, button and user alternately.Described vitro program controlled instrument 14 comprises a wireless communication module, its for described pulse generator 11 radio communication.This communication can be radio communication or near-field coupling communication etc.Wherein, the communication band of Radio-Frequency Wireless Communication device comprises 401MHz-406MHz, 420-445MHz, 2.3GHz-2.5GHz.The wearing body communication distance and can reach 1m or more of described vitro program controlled instrument 14 and described pulse generator 11.
Refer to Fig. 3, the method for work of described pulse generator 11 comprises the following steps:
Step S10, is detected the capacitance C2 of capacitance C1 and the negative sense stimulation electric capacity 118 obtaining described forward stimulation electric capacity 117, and enters step S11 by capacitive detection module 113;
Step S11, stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to be pre-charged by described power module 112 respectively to described forward, and enters step S12;
Step S12, judges that described forward stimulates electric capacity 117 and negative sense to stimulate the voltage of electric capacity 118 whether to reach setting voltage value, if so, enters step S13, if not, then return step S11;
Step S13, starts an electric pulse stimulation cycle T, and obtaining this forward by signal acquisition module 115 stimulates the current voltage value V1+ of electric capacity 117 and this negative sense to stimulate the current voltage value V2+ of electric capacity 118, and enters step S14;
Step S14, uses the forward charged to stimulate electric capacity 117 to export to described contact array 120 the forward electric pulse stimulation signal that a persistent period is T1 by this channel selecting module 114, and enters step S15;
Step S15, the current voltage value V1-that described forward stimulates electric capacity 117 is obtained by signal acquisition module 115, calculate voltage V2-corresponding to charge balance according to formula C1 × (V1+-V1-)=C2 × (V2--V2+), and enter step S16;
Step S16, uses the negative sense charged to stimulate electric capacity 118 to export a negative sense electric pulse stimulation signal by this channel selecting module 114 to described contact array 120, and enters step S17;
Step S17, judges that described negative sense stimulates the voltage of electric capacity 118 whether to equal V2-, if so, enters step S18, if not, then return step S16;
Step S18, stops exporting negative sense electric pulse stimulation signal, records the time T2 that this output negative sense electric pulse stimulation signal continues, calculate T3=T-T1-T2, and enter step S19;
Step S19, stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to recharge by described power module 112 respectively to described forward, and enters step S20 and step S22;
Step S20, judges that described forward stimulates electric capacity 117 and negative sense to stimulate the voltage of electric capacity 118 whether to reach setting voltage value, if so, enters step S21, if not, then return step S19;
Step S21, stops step S22, keeps standby until charging and standby total duration are T3, terminates an electric pulse stimulation cycle T, and return step S13;
Step S22, judges that whether recharge duration reaches T3, if so, enters step S23, if not, then returns step S19; And
Step S23, stops step S20, terminates an electric pulse stimulation cycle T, and return step S13.
Refer to Fig. 4, further, in described step S23, before returning step S13, be introduced into step S24; The method of work of described pulse generator 11 can also comprise the following steps:
Step S24, judges that described forward stimulates electric capacity 117 or negative sense to stimulate electric capacity 118 whether to be full of, and records the read-around ratio of underfill, and enter step S25;
Step S25, judges whether the read-around ratio of underfill is Nr, if so, enters step S26, if not, then return step S13; And
Step S26, stops stimulating and notifying described vitro program controlled instrument 14 by described wireless communication module 116.
Refer to Fig. 5, further, the method for work of described pulse generator 11 can also comprise the following steps:
Step S27, terminates an electric pulse stimulation cycle T, and what return step S13 judges whether the electric pulse stimulation time reaches Td before, if so, just returns step S10, if not, then still returns step S13.
In described step step S27, often again detected by capacitive detection module 113 after Td after a while and obtain described forward and stimulate the capacitance C1 of electric capacity 117 and negative sense to stimulate the capacitance C2 of electric capacity 118.Described time Td can set as required.Described time Td can be 5 minutes ~ 5 days.In the present embodiment, described time Td is 24 hours.
Refer to Fig. 6, further, the method for work of described pulse generator 11 can also comprise the following steps:
Step S28, terminates an electric pulse stimulation cycle T, return step S13 before judge whether meet to the condition organizing shorted on both ends to discharge, if so, enter step S29, if not, then continue to return step S13; And
Step S29, to organizing shorted on both ends to discharge once, and then returns step S13.
In described step step S28, the described condition to organizing shorted on both ends to discharge comprises but not only comprises: the electric pulse stimulation time reaches Ts, system reboot, stimulus parameter is changed, and external function triggers, and described forward stimulates electric capacity 117 electric voltage exception, described negative sense stimulates electric capacity 118 electric voltage exception, described forward stimulates electric capacity 117 to discharge with being shorted to, and described negative sense stimulate electric capacity 118 to discharge with being shorted in any one, can set as required.Described time Ts can set as required.Described time Ts can be 5 milliseconds ~ 10 seconds.In the present embodiment, described time Ts is 1 second.
In described step step S29, by cut-off switch 1194 and switch 1195, and of short duration for switch 1196 closing is realized this function.
Refer to Fig. 7, further, the method for work of described pulse generator 11 can also comprise the following steps:
Step S30, terminates an electric pulse stimulation cycle T, returns the condition judging whether to meet capacity earth electric discharge before of step S13, if so, enters step S31, if not, then continue to return step S13; And
Step S31, stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to discharge once with being shorted to described forward, and then returns step S11.
In described step step S30, the condition of described capacity earth electric discharge comprises but not only comprises: the electric pulse stimulation time reaches Tc, system reboot, stimulus parameter is changed, external function triggers, described forward stimulates electric capacity 117 electric voltage exception, and described negative sense stimulates any one in electric capacity 118 electric voltage exception, can set as required.Described time Tc can set as required.Described time Tc can be 5 milliseconds ~ 30 seconds.In the present embodiment, described time Tc is 2 seconds.
In described step step S31, particularly, first cut-off switch 1190, switch 1191, switch 1194 and switch 1195, then Closing Switch 1192 and switch 1193, after described forward stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to reach earth potential, cut-off switch 1192 and switch 1193.
Be appreciated that the method for work of described pulse generator 11 can also comprise above-mentioned steps S24 to step S31 simultaneously.
In described step S10, detecting described forward by capacitive detection module 113 stimulates electric capacity 117 and negative sense to stimulate the method for the capacitance of electric capacity 118 comprise but not only comprise: by resistance in conjunction with testing capacitance build single order RC link mode and in real time Detection capacitance charge status with Detection capacitance capacitance.
Refer to Fig. 8, in the present embodiment, the detection method of its correspondence specifically comprises the following steps:
Step S101, stimulates described forward electric capacity 117 and negative sense to stimulate electric capacity 118 difference ground connection electric discharge electric discharge until earth potential, and enters step S102.Particularly, in this step, first cut-off switch 1190, switch 1191, switch 1194 and switch 1195, then Closing Switch 1192 and switch 1193, after described forward stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to reach earth potential, cut-off switch 1192 and switch 1193.
Step S102, exports fixing DC voltage Vt and-Vt respectively by described positive direct-current outfan 1131 and negative DC output end 1132, and enters step S103.Particularly, in this step, this positive direct-current outfan 1131 and negative DC output end 1132 output impedance are respectively R11 and R21.
Step S103, stimulate electric capacity 117 and negative sense to stimulate electric capacity 118 to charge to described forward respectively by described capacitive detection module 113, meanwhile, described timer 1133 starts timing, and enters step S104 and step S107.Particularly, in this step, the accurate measurement resistance being Rcal by two resistances of described capacitive detection module 113 inside stimulates electric capacity 117 and negative sense to stimulate electric capacity 118 to charge to described forward respectively.
Step S104, judges that described forward stimulates electric capacity 117 both end voltage Vc1 whether to reach 0.5Vt, if so, enters step S105, if not, then return step S103.Particularly, in this step, carrying out setting analog quantity by described microcontroller 1101 to described DA output module 1102 is 0.5Vt, and by the analog quantity 0.5Vt that described DA output module 1102 exports, described comparator 1103 is set, and stimulate electric capacity 117 both end voltage Vc1 to compare by described comparator 1103 with described forward, and comparative result is fed back to described microcontroller 1101.
Step S105, timer 1133 Tt1 writing time, calculate the capacitance Ct11 that described forward stimulates electric capacity 117, and enter step S106.Particularly, in this step, according to formula
calculate the capacitance Ct11 that described forward stimulates electric capacity 117.
Step S106, repeat above step S101, step S102, step S103, step S104 and step S105 altogether (N-1) is secondary, draw described forward stimulate electric capacity 117 capacitance Ct12, Ct13 ... Ct1N, and to Ct11, Ct12 ... Ct1N is averaged the capacitance Ct1 stimulating electric capacity 117 as described forward.Particularly, in this step, N≤5.
Step S107, judges that described negative sense stimulates electric capacity 118 both end voltage Vc2 whether to reach-0.5Vt, if so, enters step S108, if not, then return step S103.Particularly, the Methods and steps S104 in this step is identical, stimulates electric capacity 118 both end voltage Vc2 to compare, and comparative result is fed back to described microcontroller 1101 by described comparator 1103 with negative sense.
Step S108, timer 1133 Tt2 writing time, calculate the capacitance Ct21 that described negative sense stimulates electric capacity 118, and enter step S109.Particularly, in this step, according to formula
calculate the capacitance Ct21 that described negative sense stimulates electric capacity 118.
Step S109, repeat above step S101, step S102, step S103, step S107 and step S108 altogether (N-1) is secondary, draw described negative sense stimulate electric capacity 118 capacitance Ct22, Ct23 ... Ct2N, and to Ct21, Ct22 ... Ct2N is averaged the capacitance Ct2 stimulating electric capacity 118 as described negative sense.Particularly, in this step, N≤5.
In described step S12, obtaining this forward by signal acquisition module 115 stimulates electric capacity 117 and negative sense to stimulate the current voltage value of electric capacity 118, and stimulate electric capacity 117 and negative sense to stimulate the voltage of electric capacity 118 and setting voltage value to contrast described forward by described comparator 1103, and comparative result is fed back to microcontroller 1101.
In described step S11, the method stimulating electric capacity 117 and negative sense to stimulate electric capacity 118 to be pre-charged to described forward by described power module 112 exports relevant with described power module 112 for unidirectional current exports still alternating current.
In one embodiment, described power module 112 is unidirectional current output, and the method to capacitor charging specifically comprises the steps:
Step S111, exports the forward stimulation voltage Vpr of expectation and the negative sense stimulation voltage-Vnr of expectation, respectively as the reference voltage of comparator 1103 by described microcontroller 1101 by described DA output module 1102;
Step S112, by described positive voltage output end 1122 for described forward stimulates electric capacity 117 to charge, simultaneously by described negative voltage outfan 1121 for described negative sense stimulates electric capacity 118 to charge;
Step S113, when described forward stimulates electric capacity 117 both end voltage Vc1 to equal the forward stimulation voltage Vpr expected, cut-off switch 1190 stops charging; When described negative sense stimulates electric capacity 118 both end voltage Vc2 to equal the negative sense stimulation voltage-Vnr expected, cut-off switch 1191 stops charging;
Step S114, when described forward stimulation electric capacity 117 both end voltage Vc1 equals the forward stimulation voltage Vpr of expectation and described negative sense stimulates electric capacity 118 both end voltage Vc2 to equal the negative sense stimulation voltage-Vnr expected, continue standby until this charging stage duration reaches T3;
Step S115, when the single charge time reaches setting value T3, even if described forward stimulates electric capacity 117 both end voltage Vc1 still lower than the forward stimulation voltage Vpr expected, cut-off switch 1190 stops charging; Even if described negative sense stimulates electric capacity 118 both end voltage Vc2 still higher than the negative sense stimulation voltage-Vnr expected, cut-off switch 1191 stops charging.
In another embodiment, described power module 112 is alternating current output, and the method to capacitor charging specifically comprises the steps:
Step S111A, exports the forward stimulation voltage Vpr of expectation and the negative sense stimulation voltage-Vnr of expectation, respectively as the reference voltage of comparator 1103 by described microcontroller 1101 by described DA output module 1102;
Step S112A, makes described positive direct-current outfan 1131 instantaneous output voltage v+ and makes described negative DC output end 1132 instantaneous output voltage v-; Particularly, in this step, export same AC signal to this positive direct-current outfan 1131 respectively by described power module 112 and negative DC output end 1132 forms instantaneous output voltage v+ and v-, that is, v+=v-simultaneously; Or also can be first same AC signal is carried out positive and negative half-wave separation, then export this positive half-wave and negative half-wave to this positive direct-current outfan 1131 respectively and negative DC output end 1132 forms instantaneous output voltage v+ and v-.
Step S113A, when described positive direct-current outfan 1131 instantaneous output voltage v+ is greater than the voltage Vc1 at described forward stimulation electric capacity 117 two ends and this voltage Vc1 is less than the forward stimulation voltage Vpr of expectation, switch 1190 closes, by described positive voltage output end 1122 for described forward stimulates electric capacity 117 to charge, otherwise switch 1190 remains open; When described negative DC output end 1132 instantaneous output voltage v-is less than the voltage Vc2 at described negative sense stimulation electric capacity 118 two ends and this voltage Vc2 is greater than the negative sense stimulation voltage-Vnr of expectation, switch 1191 closes, by described negative voltage outfan 1121 for described negative sense stimulates electric capacity 118 to charge, otherwise switch 1191 remains open;
Step S114A, when described forward stimulates electric capacity 117 both end voltage Vc1 to equal the forward stimulation voltage Vpr expected, cut-off switch 1190 stops charging; When described negative sense stimulates electric capacity 118 both end voltage Vc2 to equal the negative sense stimulation voltage-Vnr expected, cut-off switch 1191 stops charging;
Step S115A, when described forward stimulation electric capacity 117 both end voltage Vc1 equals the forward stimulation voltage Vpr of expectation and described negative sense stimulates electric capacity 118 both end voltage Vc2 to equal the negative sense stimulation voltage-Vnr expected, then standby until this charging stage duration reaches T3;
Step S116A, when the single charge time reaches setting value T3, even if described forward stimulates electric capacity 117 both end voltage Vc1 still lower than the forward stimulation voltage Vpr expected, cut-off switch 1190 stops charging; Even if described negative sense stimulates electric capacity 118 both end voltage Vc2 still to stop charging higher than the negative sense stimulation voltage-Vnr expected, cut-off switch 1191.
Implantable nerve stimulating system of the present utility model has the following advantages.The first, this implantable nerve stimulating system provides multichannel pulse output function, based on the active charge balancing function of capacitor charge and discharge, has active charge balancing function.The second, the active charge balancing function of this implantable nerve stimulating system possesses high-precision characteristic, greatly reduces neural tissue injury, substantially increases the safety of system, realizes high-precision means cost in power consumption extremely low simultaneously.3rd, owing to there is not resistance in the main output loop of energy, be operated in the dissipative cells such as the MOS of saturation region, also have benefited from the characteristic of the extremely low-yield dissipation of capacitance energy storage element, make system possess splendid energy efficiency.4th, this implantable nerve stimulating system system bulk is little, is applicable to the characteristic that implantable medical device volume is limited.The above-mentioned implantable nerve stimulating system with active charge balancing function and charge balancing method thereof, independent of the stimulation object of implantable nerve stimulating system, can be applicable to all kinds of implantable nerve stimulating system.
In addition, those skilled in the art can also do other changes in this utility model spirit, and these changes done according to this utility model spirit all should be included in this utility model scope required for protection.
Claims (10)
1. an implantable nerve stimulating system, it comprises: a pulse generator, a stimulating electrode, and a vitro program controlled instrument; It is characterized in that, described pulse generator comprises:
One power module, this power module comprises a positive voltage output end and a negative voltage outfan;
One control module, this control module comprises a microcontroller, a DA output module and a comparator;
One channel selecting module be electrically connected with this control module, this channel selecting module is used for the contact array of this pulse generator with described stimulating electrode to be electrically connected;
One forward stimulates electric capacity and a negative sense to stimulate electric capacity, and described forward stimulates electric capacity to stimulate the capacitance of electric capacity consistent with described negative sense, and described forward stimulates electric capacity and described negative sense to stimulate electric capacity ground connection respectively;
Described positive current outfan stimulates electric capacity to be electrically connected by first switch controlled by this control module with described forward, for stimulating capacitor charging for described forward; Described negative voltage outfan stimulates electric capacity to be electrically connected by the 3rd switch that is controlled by this control module with described negative sense, for stimulating capacitor charging for described negative sense;
Described forward stimulates electric capacity to be electrically connected with described channel selecting module by a second switch controlled by this control module, for providing forward stimulation voltage to described channel selecting module; Described negative sense stimulates electric capacity to be electrically connected with described channel selecting module, for providing negative sense stimulation voltage to described channel selecting module by the 4th switch that is controlled by this control module;
One capacitive detection module be electrically connected with this control module, this capacitive detection module comprises the positive current outfan and a negative current outfan stimulating electric capacity to be electrically connected with this negative sense that a timer, stimulates electric capacity to be electrically connected with this forward, and this capacitive detection module stimulates electric capacity and described negative sense to stimulate the capacitance of electric capacity for detecting described forward;
One signal acquisition module be electrically connected with this control module, and this signal acquisition module stimulates electric capacity and described negative sense to stimulate electric capacity to be electrically connected respectively with described forward, stimulate electric capacity and negative sense to stimulate the magnitude of voltage of electric capacity for gathering described forward;
One wireless communication module be electrically connected with this control module; And
One shell, this shell is for accommodating above-mentioned module.
2. implantable nerve stimulating system as claimed in claim 1, is characterized in that, the 5th switch ground connection that described forward stimulates the second end of electric capacity also to be controlled by this control module by one.
3. implantable nerve stimulating system as claimed in claim 2, is characterized in that, the 6th switch ground connection that described negative sense stimulates the second end of electric capacity also to be controlled by this control module by one.
4. implantable nerve stimulating system as claimed in claim 3, it is characterized in that, the wire that definition connects described 5th switch and described channel selecting module is the first wire, and the wire that definition connects described 6th switch and described channel selecting module is the second wire; And the 7th switch controlled by this control module is set between described first wire and the second wire.
5. implantable nerve stimulating system as claimed in claim 1, it is characterized in that, described shell is a biocompatible metal shell, uses as an electrode contacts when electricity irritation.
6. implantable nerve stimulating system as claimed in claim 5, it is characterized in that, described channel selecting module is electrically connected with described shell, and possesses the function of the earthing of casing of the contact array of described stimulating electrode and described pulse generator.
7. implantable nerve stimulating system as claimed in claim 1, is characterized in that, described microcontroller, is interconnected between described DA output module and described comparator; It accesses this DA output module by the digital output of this microcontroller and exports corresponding analog quantity, and this analog quantity is accessed this comparator to set the comparative voltage of this comparator, and exports the Output rusults of this comparator in real time.
8. implantable nerve stimulating system as claimed in claim 1, it is characterized in that, described power module is also electrically connected with described channel selecting module, described signal acquisition module and described wireless communication module.
9. implantable nerve stimulating system as claimed in claim 1, it is characterized in that, described positive direct-current outfan, described negative DC output end and described timer are electrically connected with described microcontroller respectively.
10. implantable nerve stimulating system as claimed in claim 1, is characterized in that, comprises one further for connecting the extension lead of this stimulating electrode and this pulse generator.
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| CN201520145741.9U CN204485064U (en) | 2015-03-16 | 2015-03-16 | A kind of implantable nerve stimulating system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689470A (en) * | 2015-03-16 | 2015-06-10 | 北京品驰医疗设备有限公司 | Implantable neuro-stimulation system |
| CN107773842A (en) * | 2016-08-24 | 2018-03-09 | 四川锦江电子科技有限公司 | A kind of floating earth-current stimulation circuit |
| CN108939294A (en) * | 2017-05-17 | 2018-12-07 | 苏州景昱医疗器械有限公司 | Self-adaptive control module and implantable nerve stimulating system, control method |
| CN109954206A (en) * | 2017-12-22 | 2019-07-02 | 苏州景昱医疗器械有限公司 | Voltage adaptive controlling module and implantable nerve stimulating system with it |
-
2015
- 2015-03-16 CN CN201520145741.9U patent/CN204485064U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689470A (en) * | 2015-03-16 | 2015-06-10 | 北京品驰医疗设备有限公司 | Implantable neuro-stimulation system |
| CN107773842A (en) * | 2016-08-24 | 2018-03-09 | 四川锦江电子科技有限公司 | A kind of floating earth-current stimulation circuit |
| CN108939294A (en) * | 2017-05-17 | 2018-12-07 | 苏州景昱医疗器械有限公司 | Self-adaptive control module and implantable nerve stimulating system, control method |
| CN109954206A (en) * | 2017-12-22 | 2019-07-02 | 苏州景昱医疗器械有限公司 | Voltage adaptive controlling module and implantable nerve stimulating system with it |
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Effective date of registration: 20160922 Address after: 102200 Beijing city Changping District Nan Shao Zhen Xing Chang Road No. 1 Building 1 layer 5 Patentee after: Beijing Pins Medical Co., Ltd. Address before: 102200 Beijing city Changping District Nan Shao Zhen Xing Chang Road No. 1 Building 1 layer 5 Patentee before: Beijing Pins Medical Co., Ltd. Patentee before: Tsinghua University |