CN106097283A - A kind of multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic - Google Patents
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Abstract
The invention discloses a kind of multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, including: gather digital X-ray image, and be normalized;Carry out gamma correction, color space conversion, obtain the image of XYZ color space, and carry out the simulation of hard copy;Gray proces, carries out channel decomposition, obtains cone image and retinal rod image;Laplacian pyramid algorithm is utilized respectively image to be carried out multi-resolution decomposition;Carry out brightness and contrast adaptive;Carry out sensing and threshold processing;Image merges respectively, and is combined rear image and carries out adverse transference sense and inverse gain process, it is achieved the image reconstruction of laplacian pyramid, obtains rebuilding image;Processing rebuilding image normalization, and normalization gained image is carried out color space conversion and gamma correction, rgb color space image after being corrected also exports.The present invention can carry out contrast enhancing effectively to X-ray image and details strengthens, it is possible to more preferably weakens the noise impact on X-ray image.
Description
Technical field
The present invention relates to a kind of multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, belong at image
The technical field of reason.
Background technology
Breast carcinoma is the modal a kind of malignant tumor of women.Adding up according to World Health Organization (WHO), the whole world has more than 50 every year
Ten thousand women die from breast carcinoma, are diagnosed with breast carcinoma more than 1,200,000 women, and sickness rate constantly rises, and increase crowd master
If from developing country.Early detection is the most important means reducing Death Rate of Breast Cancer.Clinical screening and Diagnosis of Breast
The method of cancer mainly have physical examination, serum female/progesterone receptor level measure and imaging diagnosis, wherein imaging diagnosis exists
The inspection of breast carcinoma occupies very important status.And with X-ray photographic diagnosis of technique breast lesion, it is acknowledged as diagnosis breast
The method most effective, most reliable of adenocarcinoma.
And during the radiophotography of X-ray image, owing to the x-ray in the complexity of breast tissue and imaging system dissipates
Penetrate, the impact of the various unfavorable factors such as electro instrument noise, cause the decline of picture quality, mainly show as that details is fuzzy, contrast
Difference, thus affect analysis and the diagnosis of doctor.Especially in breast carcinoma in early days, the sign Microcalcification granule of canceration is at x-ray figure
Show the trickleest in Xiang, it is difficult to be noticeable.Therefore, X-ray image is carried out enhancement process, be doctor when diagnosing can not or
The step lacked.
Traditional image enchancing method has histogram equalization process, edge enhancement process etc., and they can be effectively improved figure
The contrast of picture, reaches to strengthen the visual effect of image.But, traditional image enchancing method can not strengthen x-ray figure effectively
Details in Xiang, especially the best to the details reinforced effects of Microcalcification granule.Therefore the need that X-ray image details strengthens cannot be met
Ask.
Summary of the invention
The technical problem to be solved is to overcome the deficiencies in the prior art, it is provided that a kind of based on human vision system
The multiple dimensioned X-ray image Enhancement Method of system characteristic, can not strengthen in X-ray image solving traditional image enchancing method effectively
Details, especially the best to the details reinforced effects of Microcalcification granule problem.
The present invention solves above-mentioned technical problem the most by the following technical solutions:
A kind of multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, including:
Step (1) gathers digital X-ray image A, and is normalized the pixel value of digital X-ray image A,
To image
Step (2) is to described imageCarry out gamma correction, color space conversion, obtain the image of XYZ color space
And by imagePixel be expressed as physical brightness value, obtain the analog image C of hard copy;
Step (3) carries out gray proces to the analog image C of described hard copy, according to the human eye cone, the spy of rod cell
Property carries out channel decomposition, obtains cone image CconeWith retinal rod image Crod;
Step (4) utilizes laplacian pyramid algorithm respectively to cone image CconeWith retinal rod image CrodCarry out many chis
Degree decomposes;
Step (5) is to the cone image C after described decompositionconeWith retinal rod image CrodCarry out brightness and contrast adaptive;
Step (6) is to the cone image C after described adaptationconeWith retinal rod image CrodCarry out sensing and threshold processing;
Cone image after step (6) processes and retinal rod image are merged by step (7) respectively, and are combined rear image and enter
Row adverse transference sense and inverse gain process, it is achieved the image reconstruction of laplacian pyramid, obtain rebuilding image C ';
Described reconstruction image C ' is normalized by step (8), obtains the image after normalizationAnd to image
Carry out color space conversion and gamma correction, the rgb color space image after being correctedAnd export.
Further, as a preferred technical solution of the present invention: the analog image C of hard copy in described step (2)
Pixel value be:
Wherein, (X, Y, Z) is the pixel value of image C;(XW, YW, ZW) it is the brightness value of white light;For image's
Pixel value;LmaxMaximum for brightness;LminMinima for brightness;LambientFor environmental light brightness.
Further, as a preferred technical solution of the present invention: cone image C in described step (3)coneAnd retinal rod
Image CrodPixel value be:
Xcone=0.3897X+0.6890Y-0.0787Z=X
Xrod=-0.702X+1.039Y+0.433Z=0.77X
Wherein, XconeRepresent cone image CconePixel value, XrodRepresent retinal rod image CrodPixel value.
Further, as a preferred technical solution of the present invention: described step (4) is by cone image CconeCarry out many
Scale Decomposition is:
LPCone, n+1=fDOWN(LPCone, n), LPCone, 0=Ccone 0≤n≤N
BPCone, n=LPCone, n-fUP(LPCone, n+1) 0≤n < N
Wherein LPCone, nAnd BPCone, nRepresent cone image C respectivelyconeLow pass pyramid and the logical pyramidal n-th layer of band
Image, N is pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function;
And, by retinal rod image CrodCarrying out multi-resolution decomposition is:
LPRod, n+1=fDOWN(LPRod, n), LPRod, 0=Crod≤ n < N
BPRod, n=LPRod, n-fUP(LPRod, n+1) 0≤n < N
Wherein LPRod, nAnd BPRod, nRepresent retinal rod image C respectivelyrodLow pass pyramid and the logical pyramidal n-th layer figure of band
Picture, N is pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function.
Further, as a preferred technical solution of the present invention: described step (5) is to the cone figure after described decomposition
As CconeWith retinal rod image CrodCarry out brightness and contrast adaptive, including,
Described band is led to pyramidal n-th layer image BP by step (5.1)Cone, nAnd BPRod, nCalculate cone signal respectively and regard
The gain factor G of bar signalconeAnd Grod;
Step (5.2) is by the gain factor G of tried to achieve cone signalconePyramidal n-th layer image BP logical with bandCone, n
It is multiplied, obtains contrast adaptation image ABPCone, n;And the gain factor G by tried to achieve retinal rod signalrodLogical with band pyramidal
N-th layer image BPRod, nIt is multiplied, obtains contrast adaptation image ABPRod, n;
Step (5.3) is according to the low pass pyramid n-th layer image LP of cone signalCone, NCalculate and obtain gain factor, and
To this gain factor and low pass pyramidal n-th layer image LPCone, NProduct;And the low pass pyramid N according to retinal rod signal
Tomographic image LPRod, NCalculate and obtain gain factor, and obtain this gain factor and low pass pyramidal n-th layer image LPRod, NTake advantage of
Long-pending, to complete adaptation.
Further, as a preferred technical solution of the present invention: described step (8) also includes according to output image
Format adjusting imageValue.
Further, as a preferred technical solution of the present invention: described method strengthens for mammography X.
The present invention uses technique scheme, can produce following technique effect:
Based on human visual system's characteristic the multiple dimensioned X-ray image Enhancement Method that the present invention proposes, with existing method
Compare, it is an advantage of the current invention that: (1) uses multiple dimensioned Enhancement Method can avoid the limitation of single yardstick Enhancement Method
Property, grain effect will not be produced;(2) the multi-scale enhancement method based on human visual system's characteristic of the present invention, it is possible to for
The sensitivity characteristic of human eye so that the reinforced effects of contrast and details is the best, is more suitable for eye-observation, it is also possible to more preferably
Ground weakens the noise impact on X-ray image.
Therefore, the method for the present invention can carry out contrast enhancing effectively to X-ray image and details strengthens, and enables in particular to
Strengthen Microcalcification granule, be suitably applied the diagnosis of breast carcinoma of early stage, it is possible to the diagnosis efficiency being effectively improved medical personnel is same
Time reduce misdiagnosis rate, be the medical image enhancement method of a kind of practicality.
Accompanying drawing explanation
Fig. 1 is based on human visual system's characteristic the multiple dimensioned X-ray image Enhancement Method flow chart of the present invention.
Fig. 2 (a) is original image.
Fig. 2 (b) is the enhancing image of traditional histogram equalization method.
Fig. 2 (c) is the enhancing image using image averaging strategy in the inventive method.
Fig. 2 (d) is the enhancing image using pixel Average Strategy in the inventive method.
Detailed description of the invention
Below in conjunction with Figure of description, embodiments of the present invention are described.
As it is shown in figure 1, the present invention devises a kind of multiple dimensioned X-ray image enhancing side based on human visual system's characteristic
Method, the method is applicable to medical image enhancement method, specifically includes following steps:
Step (1) gathers digital X-ray medical image.
Utilize equipment to gather digitized X-ray image A, and the pixel value of A is normalized, obtain
Step (2) carries out gamma correction, color space conversion and the simulation of hard copy to image, specific as follows:
First, to described imageCarry out gamma correction, obtain imageThat is:
Wherein, v represents the image pixel value after correction, belongs to non-linear rgb color space;V represents the front image of correction
Pixel value, belongs to linear rgb color space, and the span of γ is between 1.8-2.6.
Secondly, to gained imageCarry out color space conversion, as a example by standard light source D65, obtain XYZ color space
ImageThat is:
Wherein (r, g b) represent imagePixel value, (X, Y, Z) representPixel value.
Finally, the maximum L of given brightnessmaxWith minima LminAnd environmental light brightness Lambient, unit is candela
Every square metre, by imagePixel value be expressed as physical brightness value, obtain the analog image C of hard copy, it may be assumed that
Wherein, (XW, YW, ZW) it is the brightness value of white light,For imagePixel value, (X, Y, Z) is image C's
Pixel value.
Step (3) carries out channel decomposition according to the characteristic of the human eye cone, rod cell, is specially as follows:
First, the analog image C of hard copy is carried out gray proces, according to the human eye cone, the different qualities of rod cell
Carry out channel decomposition, obtain cone image CcomeWith retinal rod image Crod, i.e.
Xcone=0.3897X+0.6890Y-0.0787Z=X (7)
Xrod=-0.702X+1.039Y+0.433Z=0.77X (8)
Wherein, XconeRepresent cone image CconePixel value, XrodRepresent retinal rod image CrodPixel value.
Step (4) utilizes laplacian pyramid algorithm respectively cone image and retinal rod figure to be carried out multi-resolution decomposition, tool
Body is as follows:
First, utilize laplacian pyramid algorithm to cone image CconeCarry out multi-resolution decomposition, it may be assumed that
LPCone, n+1=fDOWN(LPCone, n), LPCone, 0=Ccone0≤n < N (9)
BPCone, n=LPCone, n-fUP(LPCone, n+1) 0≤n≤N (10)
Wherein, LPCine, nAnd BPCone, nRepresent cone image C respectivelyconeLow pass pyramid and band logical pyramidal n-th
Tomographic image, N is pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function.
In like manner, to retinal rod image CrodCarry out multi-resolution decomposition, it may be assumed that
LPRod, n+1=fDOWN(LPRod, n), LPRod, 0=Crod0≤n < N (11)
BPRod, n=LPRod, n-fUP(LPRod, n+1) 0≤n < N (12)
Wherein, LPRod, nAnd BPRod, nRepresent retinal rod image C respectivelyrodLow pass pyramid and the logical pyramidal n-th layer of band
Image, N is pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function.
It is adaptive that step (5) carries out brightness and contrast to the cone image after described decomposition and retinal rod image, specific as follows:
Firstly, for cone image CconeBand lead to pyramidal n-th layer image BPCone, nWith retinal rod image CrodThe logical gold of band
The n-th layer image BP of word towerRod, n, calculate the gain factor G of cone signal and retinal rod signal respectivelyconeAnd GrodCalculating public
Formula, it may be assumed that
Wherein, I is input signal.
Image BP logical for bandCone, nAnd BPRod, n, by corresponding low-pass pictures LPCone, n+1And LPRod, n+1As input letter
Number substitute into formula (13) and (14) respectively, the gain factor G tried to achievecone(LPCone, n+1) and Grod(LPRod, n+1) respectively with
BPCone, nAnd BPRod, nIt is multiplied, obtains contrast adaptation image ABPCone, nAnd ABPRod, n, it may be assumed that
ABPCone, n=Gcone(LPCone, n+1)·BPCone, n, 0≤n < N (15)
ABPRod, n=Grod(LPRod, n+1)·BPRod, n, 0≤n < N (16)
And for low-pass pictures LPCone, NAnd LPRod, N, it is divided into two kinds of gain control strategies: the first image averaging strategy,
First try to achieve the meansigma methods of overall brightness in low-pass picturesWithObtain corresponding gain factor againWithThe final product that adaptive result is gain factor and low-pass pictures, it may be assumed that
The second pixel Average Strategy, respectively to low-pass pictures LPCone, NAnd LPRod, NEach pixel carry out gain factor
Calculate, obtain corresponding gain factor figure, the final product that adaptive result is gain factor figure and low-pass pictures, it may be assumed that
ALPcone=Gcone(LPCine, n)·LPCine, N (19)
ALProd=Grod(LPRod, N)·LPRod, N (20)
Cone image after described adaptation and retinal rod image are sensed and threshold processing by step (6), specific as follows:
Firstly, for the logical image of band, cone signal and output valve T of retinal rod sensingBP, cone, nAnd TBP, rod, nRespectively
For:
Wherein, 0≤n < N, the value of index p is as shown in the table with the corresponding relation of number of plies n:
Then, carry out threshold processing, i.e. work as TBP, cone, nOr TBP, rod, nValue more than 50 time, it is set to 50.
Then, for low-pass pictures TLPconeAnd TLProd, the most only need to calculate sensing defeated of cone signal and retinal rod signal
Go out to be worth TLP, coneAnd TLP, rod, it is not necessary to threshold processing, it may be assumed that
TLP, cone=ALPcone/|ALPcone|×30.5(ALPcone)0.5 (23)
TLP, rod=ALProd/|ALProd|×122(ALProd)0.5 (24)
Step 7: image is merged respectively, and be combined rear image and carry out adverse transference sense process and inverse gain process, real
The image reconstruction of existing laplacian pyramid, obtains rebuilding image.Specific as follows:
First, by corresponding cone image TBP, cone, nAnd TLP, coneAnd retinal rod image TBP, rod, nAnd TLP, rodClose respectively
And, it may be assumed that
TBP, n=TBP, cone, n+TBP, rod, n/ 7,0≤n < N (25)
TLP=TLP, cone+TLP, rod/7 (26)
Wherein, TBP, nAnd TLPIt is respectively the band after merging and leads to image and low-pass pictures.
Then, the image after being combined carries out adverse transference sense process, it may be assumed that
Wherein, ABPn' and ALPN' it is respectively the high fdrequency component of the contrast adaptation image after adverse transference sense processes and low frequency division
Amount.
Finally, carry out inverse gain process and image reconstruction, provide inversion gain factor Ginv(I) formula, it may be assumed that
Ginv(I)=0.555 (I+1.0)0.85 (29)
By the mean flow rate of display screenAs input signal, calculate the inverse gain factor of this signal, try to achieve ALPN' and should
The product LP of inverse gain factorN', it may be assumed that
By LPN' as the first step rebuild, carry out the inverse gain process with logical image and image reconstruction, in the process
The remaining image LP ' in low pass pyramid is tried to achieve successively according to formula (31)N-1, LP 'N-2..., LP0', finally give reconstruction figure
As C ', it may be assumed that
LPn'=Ginv(LPn+1′)ABPn′+LPn+1', 0≤n≤N (31)
C '=LP0′ (32)
Step 8: be normalized described reconstruction image, obtains the image after normalization, and image is carried out color
Color space conversion and gamma correction, rgb color space image after being corrected also exports.Specific as follows:
First, the image C ' after rebuilding is normalized, obtains the image after normalizationTo imageCarry out
Color space is changed, and obtains imageThat is:
Wherein, (r ', g ', b ') representsPixel value, (X ', Y ', Z ') representPixel value.Then to imageEnter
Row gamma correction, the image after being correctedThat is:
Wherein, v ' represents the image pixel value before correction, belongs to non-linear rgb color space, and V ' represents image after correction
Pixel value, belong to linear rgb color space, the span of γ is between 1.8-2.6.
Finally, it is preferable that according to the Format adjusting image of output imageValue, export image A ', it may be assumed that
Wherein, n is the figure place of image.
It addition, the present embodiment gives the simulation comparison example before and after X-ray image strengthens, as shown in Fig. 2 (a), for original
Image;As shown in Fig. 2 (b), for the enhancing image of traditional histogram equalization method;As shown in Fig. 2 (c), for side of the present invention
Method uses the enhancing image of image averaging strategy;As shown in Fig. 2 (d), for the inventive method uses pixel Average Strategy
Strengthen image.Thus, it is possible to find out Fig. 2 (c) and Fig. 2 (d) so that the reinforced effects of picture contrast and details is the best
Good, it is possible to preferably to weaken the noise impact on X-ray image.
Thus, based on human visual system's characteristic the multiple dimensioned X-ray image Enhancement Method that the present invention proposes can be effective
Ground carries out contrast enhancing to X-ray image and details strengthens, and enables in particular to strengthen Microcalcification granule, is suitably applied mammary gland in early days
The diagnosis of cancer, is effectively used in mammography X enhancing.The diagnosis efficiency that can be effectively improved medical personnel is same
Time reduce misdiagnosis rate, be the medical image enhancement method of a kind of practicality.
Above in conjunction with accompanying drawing, embodiments of the present invention are explained in detail, but the present invention is not limited to above-mentioned enforcement
Mode, in the ken that those of ordinary skill in the art are possessed, it is also possible on the premise of without departing from present inventive concept
Make a variety of changes.
Claims (7)
1. a multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, it is characterised in that including:
Step (1) gathers digital X-ray image A, and is normalized the pixel value of digital X-ray image A, obtains figure
Picture
Step (2) is to described imageCarry out gamma correction, color space conversion, obtain the image of XYZ color spaceAnd will figure
PicturePixel be expressed as physical brightness value, obtain the analog image C of hard copy;
Step (3) carries out gray proces to the analog image C of described hard copy, enters according to the characteristic of the human eye cone, rod cell
Row of channels is decomposed, and obtains cone image CconeWith retinal rod image Crod;
Step (4) utilizes laplacian pyramid algorithm respectively to cone image CconeWith retinal rod image CrodCarry out multiple dimensioned point
Solve;
Step (5) is to the cone image C after described decompositionconeWith retinal rod image CrodCarry out brightness and contrast adaptive;
Step (6) is to the cone image C after described adaptationconeWith retinal rod image CrodCarry out sensing and threshold processing;
Cone image after step (6) processes and retinal rod image are merged by step (7) respectively, and are combined rear image and carry out inverse
Sensing and inverse gain process, it is achieved the image reconstruction of laplacian pyramid, obtain rebuilding image C ';
Described reconstruction image C ' is normalized by step (8), obtains the image after normalizationAnd to imageCarry out
Color space conversion and gamma correction, the rgb color space image after being correctedAnd export.
The most according to claim 1, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: in described step (2), the pixel value of the analog image C of hard copy is:
Wherein, (X, Y, Z) is the pixel value of image C;(XW, YW, ZW) it is the brightness value of white light;For imagePixel
Value;LmaxMaximum for brightness;LminMinima for brightness;LambientFor environmental light brightness.
The most according to claim 1, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: cone image C in described step (3)coneWith retinal rod image CrodPixel value be:
Xcone=0.3897X+0.6890Y-0.0787Z=X
Xrod=-0.702X+1.039Y+0.433Z=0.77X
Wherein, XconeRepresent cone image CconePixel value, XrodRepresent retinal rod image CrodPixel value.
The most according to claim 1, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: described step (4) is by cone image CconeCarrying out multi-resolution decomposition is:
LPCone, n+1=fDOWN(LPCone, n), LPCone, 0=Ccone0≤n < N
BPcone,n=LPcone,n-fup(LPcone,n+1) 0≤n < N
Wherein LPCone, nAnd BPCone, nRepresent cone image C respectivelyconeLow pass pyramid and the logical pyramidal n-th layer image of band,
N is pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function;
And, by retinal rod image CrodCarrying out multi-resolution decomposition is:
LPRod, n+1=fDOWN(LPRod, n), LPRod, 0=Crod0≤n < N
BPRod, n=LPRod, n-fUP(LPRod, n+1) 0≤n < N
Wherein LPRod, nAnd BPRod, nRepresent retinal rod image C respectivelyrodLow pass pyramid and the logical pyramidal n-th layer image of band, N
For pyramidal total number of plies, fDOWNAnd fUPRespectively down sample function and upwards interpolating function.
The most according to claim 4, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: described step (5) is to the cone image C after described decompositionconeWith retinal rod image CrodCarry out brightness and contrast adaptive, bag
Include,
Described band is led to pyramidal n-th layer image BP by step (5.1)Cone, nAnd BPRod, nCalculate cone signal and retinal rod letter respectively
Number gain factor GconeAnd Grod;
Step (5.2) is by the gain factor G of tried to achieve cone signalconePyramidal n-th layer image BP logical with bandCone, nIt is multiplied,
Obtain contrast adaptation image ABPCone, n;And the gain factor G by tried to achieve retinal rod signalrodPyramidal n-th layer logical with band
Image BPRod, nIt is multiplied, obtains contrast adaptation image ABPRod, n;
Step (5.3) is according to the low pass pyramid n-th layer image LP of cone signalCone, NCalculate and obtain gain factor, and be somebody's turn to do
Gain factor and low pass pyramidal n-th layer image LPCone, NProduct;And the low pass pyramid n-th layer figure according to retinal rod signal
As LPRod, NCalculate and obtain gain factor, and obtain this gain factor and low pass pyramidal n-th layer image LPRod, NProduct,
To complete adaptation.
The most according to claim 1, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: described step (8) also includes the Format adjusting image according to output imageValue.
The most according to claim 1, multiple dimensioned X-ray image Enhancement Method based on human visual system's characteristic, its feature exists
In: described method strengthens for mammography X.
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CN112168211B (en) * | 2020-03-26 | 2024-08-09 | 成都思多科医疗科技有限公司 | Fat thickness and muscle thickness measuring method and system for abdomen ultrasonic image |
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