CN106074626A - A kind of alleviate dry and astringent antibacterial liquid of eye and preparation method thereof - Google Patents
A kind of alleviate dry and astringent antibacterial liquid of eye and preparation method thereof Download PDFInfo
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
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- A61K36/06—Fungi, e.g. yeasts
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- A61K36/064—Saccharomycetales, e.g. baker's yeast
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Abstract
The invention provides and a kind of alleviate the antibacterial liquid that eye is dry and astringent, it is made up of the raw material including following weight portion: zinc carbonate 13 parts, selenocarrageenan 15 parts, yeast chromium 26 parts, metasilicic acid 35 parts, vitamin B12 35 parts, vitamin B2 35 parts, vitamin C 35 parts, Borneolum Syntheticum 13 parts, purified water 70 100 parts.The dry and astringent antibacterial liquid of alleviation eye of the present invention, with the form of antibacterial liquid, directly acts on eye, instant effect, short treating period, no pain, and cure rate is high, has no side effect.
Description
Technical field
The invention belongs to field of health care products, especially relate to a kind of alleviate dry and astringent antibacterial liquid of eye and preparation method thereof.
Background technology
Eyes are one of most important organs of human body, adapt to social life for people and provide guarantee.It is in the information age,
Along with life style and the change of working condition of people, people have more several times than many decades in the past between at the moment, Ren Menyue
To rely on the video display terminal such as computer, TV manyly and carry out various activity, the most long-time computer work, see TV,
PSP or mobile phone is used to operate video games, meanwhile, wearing of contact lens and U.S. pupil, drive for a long time, spiritual pressure,
All it is easy to make people suffer from visual fatigue disease.
Computer: the screen of computer is made up of little phosphor dot, these phosphor dots are flickers, and wanting to see just needs
Our eyes are wanted constantly to regulate.We oneself imperceptible, but necessary being, our eyes to be deacclimatized it and are easy for
Produce fatigue.Typewriting when, eyes are wanted constantly to convert between manuscript, screen, keyboard, and the focus of eyes and distance are constantly
Ground regulation, also can make eyes feel tired.
PSP, mobile phone: even on the bus rocked, on crowded subway, even in elevator, tide-persons are the most not
Forget PSP, iPod or the MP4 playing with in hands, play game, see a film, add that custom dig-ins mobile phone mad by note, dig-in for a long time
Narrow screen, the most easily allow the eyes of people feel tired.
Contact lens, U.S. pupil: the cornea of people directly absorbs oxygen from air and breathes, now, upper cover one layer " light
Yarn ", the oxygen of picked-up is just few.And, contact lens is located in the foreign body on cornea after all with U.S. pupil, and eyes are each time
Blink, it all can be made to produce certain friction with eyeball surface.So, long-time or continuous contact lens or U.S. pupil, all
Cornea can be made to be in lasting anaerobic condition, cause corneal epithelium edema, erosion.If with the presence of antibacterial or virus, it is possible to
Cause keratitis, even form corneal ulcer.
Drive for a long time: eyes extremely stare at front, spirit high-pressure, this be every day early evening peak drive the cognition of race.Add
The pockets such as upper overpass, access tunnel are walked around the test that eyes just can be allowed to endure high light all angles to the fullest extent.Although not reaching fatigue
Drive, but eyes are the most tired.
Stress: because dysthymia, pressure are excessive, immunologic balance is broken and excessive by eye intensity, all can be direct
Affect the properly functioning of eyes.This is because, when human body nervous, anxiety occurs and the unhealthy emotion such as constrains, on hypophysis cerebri, kidney
Hormone secretion will reduce relatively so that stereopsis vision conduction and visual information machining functions are in low-level state, meeting
Directly result in crystal and eye muscle shrinks and diastole step is inharmonious.
Summary of the invention
In view of this, it is contemplated that propose a kind of to alleviate dry and astringent antibacterial liquid of eye and preparation method thereof, formula is simple,
Preservative free.
For reaching above-mentioned purpose, the technical scheme is that and be achieved in that:
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 1-3 part, selenizing
Carrageenan 1-5 part, yeast chromium 2-6 part, metasilicic acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, vitamin C 3-
5 parts, Borneolum Syntheticum 1-3 part, purified water 70-100 part.
Further, the described antibacterial liquid alleviating eye dry and astringent is made up of the raw material including following weight portion: zinc carbonate 2-3
Part, selenocarrageenan 2-5 part, yeast chromium 2-5 part, metasilicic acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, dimension
Raw element C 3-5 part, Borneolum Syntheticum 1-3 part, purified water 70-90 part.
Further, the described antibacterial liquid alleviating eye dry and astringent is made up of the raw material including following weight portion: zinc carbonate 2-3
Part, selenocarrageenan 2-3 part, yeast chromium 2-3 part, metasilicic acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, dimension
Raw element C 3-5 part, Borneolum Syntheticum 1-3 part, purified water 70-90 part.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) purified water is carried out high temperature sterilize, cool down, filter after stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Further, in described step (1), high temperature sterilize step temperature is 100-125 DEG C, time 20-30min.
Further, in described step (1), filtration step is membrane filtration.
Further, described step (2) also includes after blend step ultrasonic, filter, sterilization steps.
The described purposes alleviating the dry and astringent antibacterial liquid of eye, described alleviates the dry and astringent antibacterial liquid of eye in preparation
Alleviate the application in the product that eye strain is dry and astringent with eye.
In described selenocarrageenan, the content of selenium element is 0.8%-1.2%, organic selenium in described selenocarrageenan
Content more than 90%.
In described yeast chromium, the content of chromium element is less than or equal to 0.2%.
The described using method alleviating the dry and astringent antibacterial liquid of eye: every day 3-5 time, each 1-2 drips, general 15-30 days
Just can improve.
In the present invention, containing zinc element in zinc carbonate, zinc is one of trace element of needed by human, grows growth in humans
During play an important role.
The important function of zinc: the promotion growth promoter of human body, enhancing immunity, zinc deficiency, visual problems: visual deterioration, holds
It is easily caused night vision difficulty, myopia, hypermetropia, astigmatism etc..
In the present invention, selenocarrageenan belongs to selenium polysaccharide class, for organic selenium compound, has more preferably than inorganic selenium compound
Bioavailability and physiologic gain effect.Effect of selenium: owing to selenium is some antioxidases and selenium-P in animal and human body
The important component part of albumen, plays a part balance oxidation reduction atmosphere in vivo, and research proof has raising animal immune
Power effect.
The important function of selenium: prevent cataract: retina is more due to contact computer radiate etc., and subject to damage, selenium can be protected
Eyesight protecting net film, the fineness of reinforcing glass body, improves vision, prevents cataractous effect.
In the present invention, yeast chromium is that the chromium nutrition that State Food and Drug Administration specifies supplements one of source.Chromium is
One of necessary trace element of human body.During internal scarce chromium, insulin function substantially reduces, thus blood glucose raises, and causes blood to ooze
Change, the most crystalline and aqueous humor osmotic pressure is thoroughly pressed also to change.When aqueous humor osmotic pressure is less than crystalline lens osmotic pressure, aqueous humor is just
In entrance crystalline lens, making crystalline lens become convex, increase diopter, reflection is fuzzy, i.e. causes myopia.
In the present invention, metasilicic acid has health care to human body cardiovascular, bone growth etc..Relevant information is reported: silicon partially
Acid has the function of good vessel softening to human body, and the blood vessel wall of people can be made to keep elasticity；The elastic force that silicon can strengthen blood vessel is fine
Dimension intensity, particularly inner membrance elastic layer, may make up one barrier to invade in hindering lipid.Therefore, to have anti-atherogenic hard for silicon
The effect changed, may precisely due to silicon can play holding elastic fibers and interstitial integrity, thus prevent ocular angiogenesis hardening and
Increase the effect of blood vessel elasticity.
In the present invention, vitamin B12 participates in the conversion of internal methyl and folic acid metabolism, promotes Isosuccinic acid to be changed into succinum
Acid, thus participate in tricarboxylic acid cycle, the synthesis of neural myelinic phospholipid and the integrity of maintenance myelinated nerve fiber function have important
Effect.
In the present invention, vitamin B2 promotes to grow and the regeneration of cell, promotes vision, alleviates the fatigue of eyes, affect people
The body absorption to ferrum.During Vitamin B2 deficiency, just affect the biological oxidation of body, make metabolism generation obstacle.The many performances of its pathological changes
For mouth, eye and the inflammation at external genitalia position.
In the present invention, vitamin C is one of composition of composition eyeball crystalline lens.If be deficient in vitamin, C is easy for suffering from water
The cataract disease of opacity of lens.
Relative to prior art, antibacterial liquid that alleviation eye of the present invention is dry and astringent and preparation method thereof has following excellent
Gesture:
(1) antibacterial liquid that alleviation eye of the present invention is dry and astringent is with the form of antibacterial liquid, directly acts on eye, takes effect
Hurry up, short treating period, no pain, cure rate is high, has no side effect.
(2) the antibacterial liquid formula that alleviation eye of the present invention is dry and astringent is simple, be easy to get, without preservative, safe and reliable,
Health.
(3) containing multi mineral prime element and vitamin in the antibacterial liquid that alleviation eye of the present invention is dry and astringent, slow
Solve eye strain, dry and astringent on the basis of supplement the nutrient substance of needed by human body, improve body immunity.
Detailed description of the invention
Unless otherwise indicated, term used herein is respectively provided with the implication that those skilled in the art's routine understands, in order to
Readily appreciate the present invention, terms more used herein have been carried out following definitions.
All of Digital ID, such as pH, temperature, time, concentration, including scope, be all approximation.It is to be understood that, although
Term " about " is all added before all of Digital ID of the clearest and the most definite narration.Simultaneously it will also be understood that, although the clearest and the most definite
Narration, reagent described herein is only example, and its equivalent is known in the art.
The present invention is described in detail below in conjunction with embodiment.
Embodiment 1
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 1 part, selenizing card
Draw 1 part of glue, yeast chromium 2 parts, metasilicic acid 3 parts, vitamin B12 4 parts, vitamin B2 4 parts, vitamin C 4 parts, Borneolum Syntheticum 1 part is pure
Change 75 parts of water.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Embodiment 2
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 1 part, selenizing card
Draw 1.5 parts of glue, yeast chromium 2 parts, metasilicic acid 3 parts, vitamin B12 4 parts, vitamin B2 4 parts, vitamin C 4 parts, Borneolum Syntheticum 1 part,
Purified water 75 parts.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Embodiment 3
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 3 parts, selenizing card
Draw 3 parts of glue, yeast chromium 3 parts, metasilicic acid 4 parts, vitamin B12 5 parts, vitamin B2 5 parts, vitamin C 5 parts, Borneolum Syntheticum 1 part is pure
Change 90 parts of water.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Embodiment 4
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 2 parts, selenizing card
Draw 3 parts of glue, yeast chromium 3 parts, metasilicic acid 4 parts, vitamin B12 5 parts, vitamin B2 5 parts, vitamin C 5 parts, Borneolum Syntheticum 1 part is pure
Change 80 parts of water.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Embodiment 5
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 2 parts, selenizing card
Draw 5 parts of glue, yeast chromium 5 parts, metasilicic acid 3 parts, vitamin B12 4 parts, vitamin B2 4 parts, vitamin C 4 parts, Borneolum Syntheticum 1 part is pure
Change 80 parts of water.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Embodiment 6
A kind of alleviate the antibacterial liquid that eye is dry and astringent, be made up of the raw material including following weight portion: zinc carbonate 2.5 parts, selenizing
Carrageenan 4 parts, yeast chromium 4 parts, metasilicic acid 3 parts, vitamin B12 4 parts, vitamin B2 4 parts, vitamin C 4 parts, Borneolum Syntheticum 1 part,
Purified water 80 parts.
The described preparation method alleviating the dry and astringent antibacterial liquid of eye, comprises the steps:
(1) after purified water is carried out high temperature sterilize (100 DEG C, 20min), cooling, membrane filtration stand-by；
(2) by zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum
Dissolve in purified water after filtration, after mix homogeneously and get final product.
Typical case one:
Zhao so-and-so, man, 20 years old, people from Nankai District, Tianjin City, suffer from eye and do, eye is puckery, and constantly firmly the disease such as nictation, opens to hospital
Part collyrium using effect is the best, starts from March 18th, 2016 through friend's introduction and begins to use the embodiment of the present invention 4 to prepare
Antibacterial liquid drop, four times a day, each 1-2 drips, and does not coordinate other therapies, the puckery remission of eye xerophthalmia after 10 days, 30
Constantly blink after it recovery from illness.
Typical case two:
Bao so-and-so, man, 36 years old, people from peace zone, Tianjin, suffer from eye do, eye puckery wait disease, opened part collyrium to hospital and made
By poor effect, start from March 18th, 2016 through friend's introduction and begin to use the prepared antibacterial liquid point of the embodiment of the present invention 5
Dripping, four times a day, each 1-2 drips, and does not coordinate other therapies, the puckery remission of eye xerophthalmia after 10 days, constantly blinks after 30 days
Eye recovery from illness.
Typical case three:
King so-and-so, man, 45 years old, people from peace zone, Tianjin, suffer from eye and do, eye is puckery waits disease, high intraocular pressure, hospital treatment 3
Month poor effect, introduces the antibacterial liquid point starting from March 20th, 2016 and beginning to use the embodiment of the present invention 6 to prepare through friend
Dripping, every day 5 times, each 1-2 drips, and does not coordinate other therapies, the puckery remission of eye xerophthalmia after 15 days, eye xerophthalmia after 30 days
Puckery recovery from illness, does not the most recur.
Typical case four:
Wear so-and-so, man, 55 years old, people from peace zone, Tianjin, to suffer from eye and do, eye is puckery, high intraocular pressure, and eye is muddy, and Fundus oculi artery is hard
Change, hospital treatment 3 months and the best with 3 months effects of collyrium, start from March 20th, 2016 through friend's introduction
Beginning to use the antibacterial liquid drop that the embodiment of the present invention 6 prepares, every day 5 times, each 1-2 drips, and does not coordinate other therapies, passes through
The puckery remission of eye xerophthalmia after 10 days, after 30 days, the puckery recovery from illness of eye xerophthalmia, does not the most recur.
Typical case five:
Pay so-and-so, man, 70 years old, people from south, Physical Culture Institute, Hexi District, Tianjin, to suffer from eye and do, eye is puckery, sees that distinguished and admirable tear and eyes are the whitest
Cataract, through hospitalize half a year, poor effect, begin to use, on April 15th, 2015, the antibacterial liquid that the embodiment of the present invention 1 prepares
Drop, every day 4-5 time, each 1-2 drips, and does not coordinate other therapies, remission after 10 days, fully recovers, substantially after 30 days
The most repeatedly, cataract is the most serious.
Typical case six:
Liu so-and-so, female, 55 years old, people from Jinnan District, Tianjin, suffer from ocular fundus arteriosclerosis, eye do, eye is puckery, keratitis, through friend
Introduction starts from January 23rd, 2016 and begins to use the prepared antibacterial liquid drop of the embodiment of the present invention 2, every day 4-5 time, each 1-
2, not coordinating other therapies, remission after 5 days, the puckery recovery from illness of eye xerophthalmia after 30 days, ocular fundus arteriosclerosis does not has substantially
Having development, after using 60 days, keratitis is almost recovered.
Typical case seven:
Zhang, female, 80 years old, people from Beichen District, Tianjin, suffer from ocular fundus arteriosclerosis, eye is done, and eye is puckery, severe cataract, eye
End muddiness, a large amount of use medicament for the eyes are not alleviated for several years, start from March 5th, 2016 through friend's introduction and begin to use the present invention real
Executing the antibacterial liquid drop that example 3 prepares, every day 6 times, each 1-2 drips, and does not coordinate other therapies, the puckery disease of eye xerophthalmia after 15 days
Shape is alleviated, the puckery recovery from illness of eye xerophthalmia after 35 days, and ocular fundus arteriosclerosis does not the most develop, and Fundus oculi artery is fullyed recover from an illness after muddy 90 days substantially
More.
From in March, 2015 in June, 2016, clinical treatment observation 190 examples, male 110 examples, female 80 example, wherein eye xerophthalmia
Puckery 190 examples, ocular fundus arteriosclerosis 50 example, cataract 30 example, high intraocular pressure 20 example, muddy 40 examples in optical fundus, real by the drop present invention
Execute the antibacterial liquid that example 3 prepares, do not coordinate additive method, the puckery basic alleviation of eye xerophthalmia after 15 days, the puckery symptom of eye xerophthalmia after 30 days
Disappear, follow up a case by regular visits to wherein 10 example, the most all do not recur.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Within god and principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (8)
1. alleviate the antibacterial liquid that eye is dry and astringent for one kind, it is characterised in that: it is made up of the raw material including following weight portion: zinc carbonate 1-
3 parts, selenocarrageenan 1-5 part, yeast chromium 2-6 part, metasilicic acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, dimension
Raw element C 3-5 part, Borneolum Syntheticum 1-3 part, purified water 70-100 part.
The antibacterial liquid that alleviation eye the most according to claim 1 is dry and astringent, it is characterised in that: described alleviation eye is dry and astringent
Antibacterial liquid is made up of the raw material including following weight portion: zinc carbonate 2-3 part, selenocarrageenan 2-5 part, yeast chromium 2-5 part, inclined silicon
Acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, vitamin C 3-5 part, Borneolum Syntheticum 1-3 part, purified water 70-90 part.
The antibacterial liquid that alleviation eye the most according to claim 2 is dry and astringent, it is characterised in that: described alleviation eye is dry and astringent
Antibacterial liquid is made up of the raw material including following weight portion: zinc carbonate 2-3 part, selenocarrageenan 2-3 part, yeast chromium 2-3 part, inclined silicon
Acid 3-5 part, vitamin B12 3-5 part, vitamin B2 3-5 part, vitamin C 3-5 part, Borneolum Syntheticum 1-3 part, purified water 70-90 part.
4. the preparation method alleviating the dry and astringent antibacterial liquid of eye according to any one of claim 1-3, it is characterised in that: include
Following steps:
(1) purified water is carried out high temperature sterilize, cool down, filter after stand-by；
(2) zinc carbonate, selenocarrageenan, yeast chromium, metasilicic acid, vitamin B12, vitamin B2, vitamin C, Borneolum Syntheticum are dissolved
In purified water after filtration, after mix homogeneously and get final product.
The preparation method of the antibacterial liquid that alleviation eye the most according to claim 4 is dry and astringent, it is characterised in that: described step
(1) in, high temperature sterilize step temperature is 100-125 DEG C, time 20-30min.
The preparation method of the antibacterial liquid that alleviation eye the most according to claim 4 is dry and astringent, it is characterised in that: described step
(1) in, filtration step is membrane filtration.
The preparation method of the antibacterial liquid that alleviation eye the most according to claim 4 is dry and astringent, it is characterised in that: described step
(2) also include after blend step in ultrasonic, filter, sterilization steps.
8. the purposes alleviating the dry and astringent antibacterial liquid of eye according to any one of claim 1-3, it is characterised in that: described is slow
Solve the application in alleviating, in preparation, the product that eye strain is dry and astringent with eye of the eye dry and astringent antibacterial liquid.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112057528A (en) * | 2019-05-22 | 2020-12-11 | 天津道和德商贸有限公司 | Eye care antibacterial solution and preparation method thereof |
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