CN106053797B - A kind of chromatographic assay system - Google Patents
A kind of chromatographic assay system Download PDFInfo
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- CN106053797B CN106053797B CN201610565345.0A CN201610565345A CN106053797B CN 106053797 B CN106053797 B CN 106053797B CN 201610565345 A CN201610565345 A CN 201610565345A CN 106053797 B CN106053797 B CN 106053797B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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Abstract
The invention discloses a kind of chromatographic assay system, including chromatography card and the chromatographic analysis instrument for reading analysis chromatography card, chromatography card includes deck and Ka Gai；Deck include deck body and be uniformly arranged on the outer peripheral face of deck body at least two radially distribution and with the snap arm at the deck body at grade, sample slot is provided with deck body, the sample holes offered sample slot and corresponding analysis bar standing groove connection on chromatography strip standing groove, the cell wall of sample slot are provided with snap arm；Ka Gai includes being provided with well on the deck body cap and snap arm lid with deck form fit, deck body cap, and snap arm, which is covered, is provided with reading window；Chromatographic analysis instrument includes analyzer lower casing；Sample results analytic unit for reading analysis chromatography strip；The chromatography card rotating unit that driving chromatography card is rotated with fixed angle.The present invention needs sample few, can continuously test and analyze the result of the different indexs of sample, simple to operate, detection efficiency is high.
Description
Technical field
The present invention relates to field of immunological detection, more particularly to a kind of chromatographic assay system.
Background technology
In field of immunological detection, chromatographic assay system generally comprises chromatography card and the layer for reading analysis chromatography card
Analyzer is analysed, chromatographic analysis instrument is the instrument for the reading analysis that current field of immunological detection is generally used, and typically requires and takes
Band is convenient, and simple to operate.The chromatographic assay system course of work is in the prior art：Sample was added in chromatography card before this
On chromatography strip, chromatography reaction is carried out to sample by chromatography strip, then reacted chromatography card is inserted into chromatographic analysis instrument, by layer
Reading is identified to the result that chromatography blocks reaction in analysis analyzer, and is analyzed, and prints testing result.At present, in market
Common chromatography card is all bar shaped chromatography card, a kind of index can only be detected, it is necessary to should after the completion of a chromatography card reading analysis
Chromatography card is exited, and is inserted into the chromatography card for detecting other indexs of sample, is carried out other result and is read analysis.Existing layer
The problem of analysis analysis system is present and shortcoming：1. each chromatography card is required for that a sample is added dropwise, the demand to sample is big；2.
Chromatographic analysis instrument can only once be read out analysis operation complexity to an index, read analysis efficiency low；3. block by chromatography
It is put into before chromatographic analysis instrument, it is necessary to which sample fully progress chromatography reaction in chromatography card, can just be put into chromatographic analysis instrument
Analysis is read out, it is necessary to which antedating response, the efficiency of detection and analysis is low.
The content of the invention
Need sample few the present invention solves the technical problem of offer one kind, and the different indexs of institute's test samples
Chromatography strip can be reacted simultaneously, and can continuously read the result of the different index of analysis sample, simple to operate, inspection
Survey the chromatographic assay system of efficiency high.
In order to solve the above technical problems, the technical solution adopted by the present invention is：A kind of chromatographic assay system includes chromatography and blocked
And the chromatographic analysis instrument of the chromatography card is analyzed for reading, the chromatography card includes deck and the Ka Gai being fastened on the deck；
What the deck included deck body and was uniformly arranged on the outer peripheral face of the deck body at least two is radially distributed
Snap arm, the deck body is disposed on the same plane with the snap arm, and sample slot is provided with the deck body, is set in the snap arm
Have offered on the chromatography strip standing groove for the cell wall outer peripheral face for extending to the sample slot, the cell wall of the sample slot by the sample slot with
The sample holes of corresponding chromatography strip standing groove connection；The Ka Gai include with the deck body shape coordinate deck body cap and
Be arranged on the snap arm lid with snap arm form fit on the outer peripheral face of the deck body cap, the deck body cap be provided with for
The well that the sample slot is loaded, the snap arm, which is covered, is provided with reading window；
The chromatographic analysis instrument includes analyzer lower casing；
Sample results analytic unit, is installed in the shell intracavitary of the chromatograph lower casing, and covered by above-mentioned snap arm
Reading window carries out digital independent analysis to the chromatography strip in above-mentioned chromatography card；
Card rotating unit is chromatographed, the shell intracavitary of above-mentioned analyzer lower casing is arranged on, and positioned at the analysis of above-mentioned sample results
The lower section of unit, the chromatography card rotating unit is used to drive above-mentioned chromatography card with the horizontal circular-rotation of fixed angle, for above-mentioned
Sample results analytic unit is read data one by one to the chromatography strip in the snap arm of the chromatography card.
Preferably, above-mentioned chromatography card rotating unit includes rotating mechanism, and is fixedly installed on the rotating mechanism
It is provided with and is matched with the outer shape of above-mentioned chromatography card in chromatography card mounting seat for assembling chromatography card, the chromatography card mounting seat
Chromatography card mounting groove, in reading process, above-mentioned chromatography clamp is fitted in the chromatography card mounting groove.
Preferably, chromatographic analysis instrument also includes being used to above-mentioned chromatography card being sent to sample knot another embodiment of the present invention
Chromatography card feed unit at fruit analytic unit position, the chromatography card feed unit is arranged on the shell chamber of above-mentioned analyzer lower casing
Interior, the chromatography card feed unit includes feeding driving mechanism, transport mechanism, position-limit mechanism, and the feeding driving mechanism drives the biography
Mechanism kinematic is sent, the position-limit mechanism limits the transmission position of the transport mechanism, above-mentioned chromatography card rotating unit also includes working as the layer
Analysis card transmits the bindiny mechanism for being connected the chromatography card with the chromatography card rotating unit when in place.
Preferably, the bindiny mechanism includes being installed on the standard shaft of the deck body lower surface of above-mentioned chromatography card, the standard shaft
The clamping set moved along standard shaft axis is equipped with by Telescopic spring elasticity, clamping set top is provided with buckling groove, the clamping
Set bottom is provided with lower buckling groove, and the standard shaft clamping projection being engaged by clamping with buckling groove on this is symmetrically arranged with the standard shaft, should
Rotary clamping projection is installed with chromatography card rotating unit, the clamping, which is put, is provided with dynamic magnetic coil, the chromatography card rotates single
It is provided with member in the raised top of the rotary clamping and determines magnetic coil, when above-mentioned chromatography card is driven in place, the dynamic magnetic
Coil determine magnetic coil adhesive with this, and then drives lower buckling groove and the raised clamping engagement of rotary clamping, and now clamping set is by layer
Analysis card is connected with chromatography card rotating unit.
Preferably, the shell intracavitary of above-mentioned analyzer lower casing is installed with transmission guide rail in the upper end of above-mentioned transport mechanism, should
Installing plate is provided with above transmission guide rail, above-mentioned sample results analytic unit is arranged on the installing plate, set on the installing plate
It is equipped with the sample collection window that information is gathered for sample results analytic unit.
Preferably, above-mentioned feeding driving mechanism is stepper motor, and the stepper motor is arranged on the terminal of above-mentioned transmission guide rail
Place, above-mentioned transport mechanism includes half gear being fixedly connected with the output shaft of the stepper motor, and is nibbled with half gear
Close and be fixedly installed sliding block on the rack of transmission, the rack, the sliding block is slidably matched with the transmission guide rail, is provided with the sliding block
For above-mentioned standard shaft and clamping set through Double-ear-hole, above-mentioned chromatography card rotating unit includes being fixedly installed on stepper motor output
On axle, and the first bevel gear on the outside of half gear, and by fixing axle rolling assembling in above-mentioned analyzer lower casing
On body, and with the second bevel gear of above-mentioned first bevel gear engaged transmission, be arranged with the fixing axle and the described second cone tooth
Take turns the axle sleeve that is fixedly connected, the rotary clamping projection is installed in the outer peripheral face of the axle sleeve, it is described to determine magnetic coil and be fixedly installed
In the upper end of the fixing axle.
Preferably, the card of above-mentioned chromatography card covers information storage Jie for being provided with the information for storing chromatography strip and sample
Matter.
Preferably, the upper surface at the top of above-mentioned deck body and above-mentioned snap arm, which is provided with grafting boss, grafting boss, sets
Spliced eye is equipped with, above-mentioned card, which is covered, is provided with the inserting column that grafting corresponding with spliced eye coordinates, and the Ka Gai is inserted by inserting column
In to spliced eye and then detachably it is fastened on deck.
Preferably, the chromatographic analysis instrument also includes control panel, the control panel and the stepper motor, position-limit mechanism,
Sample results analytic unit is electrically connected.
The beneficial effects of the invention are as follows：The chromatography card provided in the present invention only needs to disposable toward in sample slot add on a small quantity
Sample, sample is flowed into the chromatography strip standing groove in snap arm by sample holes, entered with the chromatography strip in chromatography strip standing groove
The different indexs of sample can be carried out detection reaction by row reaction.Therefore the present invention only needs a small amount of sample, it becomes possible to sample
Different indexs carry out detection and read analysis.
The chromatographic analysis instrument provided in the present invention, chromatography card is installed on the chromatographic analysis instrument, the chromatographic analysis instrument leads to
Crossing chromatography card rotating unit makes chromatography card rotate at a certain angle, analyzes the sample results that correspond to of the snap arm of chromatography card one by one
The lower section of unit, what sample results analytic unit can be one by one is read out analysis to each chromatography strip on chromatography card, realizes
The continuous reading of indexs different to sample is analyzed, and substantially increases detection efficiency；During the chromatographic analysis instrument rotation of the present invention, energy
Enough accelerate reaction speed of the sample in chromatography card, therefore, chromatographic analysis instrument of the invention shortens sample with chromatographing in card
In the chromatography reaction time of chromatography strip, further increase detection efficiency；By the rotation for the chromatography card rotating unit for adjusting chromatograph
Rotary speed, the chromatography reaction speed of sample and the chromatography strip in chromatography card can also be adjusted accordingly, so as to adjust in chromatography card
The chromatography time of sample, creative changing can only lean on the situation that sample is chromatographed naturally in chromatography card in the prior art.
The mounting seat further set, chromatography card to be mounted directly in mounting seat, just can carry out rotation reading to chromatography card
Analysis is taken, it is simple in construction, it is swift to operate, conveniently.
Chromatography card can be sent to inside chromatograph and be read out analysis by the feed unit further set, make whole layer
The structure for analysing analyzer is compacter, seals easy to carry.
The guide rail further set, can further chromatography stick into when play a part of guiding, and sample knot
Fruit analytic unit is arranged on guide rail, sample results analytic unit is closely corresponded to chromatography card, is made accuracy of detection more accurate,
More compact structure.
Feeding driving mechanism is further arranged to stepper motor, a stepper motor can drive simultaneously chromatography stick into
Unit and chromatography card rotating unit, reduce cost, reduce the overall structure of chromatographic analysis instrument.
The information storage medium further set on chromatography card, can easily read the information of sample, it is not necessary in people
Work is recorded.
Further chromatography card is arranged to demountable structure, and simple production process is more square in the interior placement chromatography strip of chromatography card
Just.
Further each function in the chromatographic assay system of the present invention is controlled by a control panel, can realize whole chromatography
The full-automation of analysis system, saves human cost, improves accuracy of detection.
Brief description of the drawings
Fig. 1 is the structural representation of the embodiment one for the chromatographic assay system that the present invention is provided；
Fig. 2 is the top view for chromatographing card rotating unit in Fig. 1；
Fig. 3 is the structural representation of the embodiment two for the chromatographic assay system that the present invention is provided；
Fig. 4 is the top view in Fig. 3；
Fig. 5 is the decomposing schematic representation for chromatographing the embodiment blocked in chromatographic assay system.
Embodiment
For the ease of understanding the present invention, below in conjunction with the accompanying drawings and specific embodiment, the present invention will be described in more detail.
The preferred embodiment of the present invention is given in accompanying drawing.But, the present invention can be realized in many different forms, not limited
In the embodiment described by this specification.On the contrary, the purpose for providing these embodiments makes to the disclosure
Understand more thorough comprehensive.
It should be noted that unless otherwise defined, all technologies and scientific terminology are with belonging to used in this specification
The implication that the those skilled in the art of the present invention are generally understood that is identical.In the description of the invention used term only
It is in order to describe the purpose of specific embodiment, to be not intended to the limitation present invention.Term "and/or" bag used in this specification
Include the arbitrary and all combination of one or more related Listed Items.
Embodiment one
Fig. 1 describes a kind of structural representation of the embodiment one of chromatographic assay system of the present invention.Can from Fig. 1
Go out the chromatographic analysis instrument 2 that the chromatographic assay system of the present embodiment includes chromatography card 1 and the chromatography card 1 is analyzed for reading.
Fig. 5 describes the structural representation of the embodiment of the chromatography card in a kind of chromatographic assay system of the present invention.By
Fig. 5 can be seen that the chromatography card includes deck 11 and the card lid 12 being fastened on the deck 11.
It is in spoke that deck 11, which includes deck body 111 and be uniformly arranged on the outer peripheral face of the deck body 111 four,
The snap arm 112 of shape distribution is penetrated, the deck body 111 is disposed on the same plane with snap arm 112, and being provided with four snap arm is
One embodiment of card is chromatographed, the structure of three, six, eight etc. multiple snap arm can also be arranged as required into, these cards
Arm is uniformly laid in the outer peripheral face of deck body, and with deck body in one plane.Set on deck body 111
There are the chromatography strip standing groove 114 that the cell wall outer peripheral face for extending to the sample slot 113 is provided with sample slot 113, snap arm 112, sample
The sample holes 115 for connecting the sample slot 113 with corresponding chromatography strip standing groove 114 are offered on the cell wall of this groove 113.
Card lid 12 is including the deck body cap 121 with the form fit of deck body 111 and is arranged on the deck body cap
With the snap arm lid 122 of the form fit of snap arm 112 on 121 outer peripheral face, being provided with the deck body cap 122 is used for sample slot
Reading window 124 is provided with 113 wells 123 being loaded, snap arm lid 122.
Preferably, deck 11 and Ka Gai 12 can be fastened using dismountable structure.It is further preferred that detachable
Structure include, the upper surface at deck body 111 and the top of snap arm 112, which is provided with grafting boss 13, grafting boss 13, to be set
There is the inserting column for being provided with and coordinating with the corresponding grafting of spliced eye 14 on spliced eye 14, card lid 12, the card lid 12 is inserted by inserting column
Enter into spliced eye 14 and then be detachably fastened on deck 11.
The chromatographic analysis instrument of the present embodiment includes analyzer lower casing 21, sample results analytic unit as seen from Figure 1
22nd, chromatography card rotating unit 23.Sample results analytic unit 22 is fixedly installed on the shell intracavitary of analyzer lower casing 21, sample knot
Fruit analytic unit 22 uses existing conventional analytical technology, passes through the layer in 124 pairs of chromatography cards 1 of reading window on snap arm lid 122
Analyse bar and carry out digital independent analysis.Chromatography card rotating unit 23 is arranged on the shell intracavitary of analyzer lower casing 21, and positioned at above-mentioned
The lower section of sample results analytic unit 22, chromatography card rotating unit 23 is used to drive chromatography card 1 with 90 ° of horizontal circular-rotations in angle,
So that above-mentioned sample results analytic unit is read data one by one to the chromatography strip in the chromatography card 1.
The course of work of the present embodiment is：The layer that first chromatography strip for needing to detect the different indexs of sample is put on deck
Analyse in bar standing groove, then sample is added drop-wise in the sample slot 113 on chromatography card 1 again, the chromatography card 1 is assembled to this implementation
On the chromatography card rotating unit 23 of chromatographic analysis instrument in example, chromatography card rotating unit 23 works, and drives chromatography card 1 with 90 ° of angles
Rotate successively, each snap arm 112 is corresponding in turn under sample results analytic unit 22, passed through by sample results analytic unit 22
The reaction result in snap arm 112 that 124 pairs of reading window on snap arm lid 122 is corresponding in turn to is read out analysis.
Chromatography card in the present embodiment only needs to disposably add a small amount of sample toward in sample slot, and sample can be by entering
Sample hole is separately flowed into the chromatography strip of different indexs, and the different indexs of sample can be detected, therefore the present embodiment
Chromatography card only needs a small amount of sample, it becomes possible to which the different indexs to sample carry out detection reading analysis.
Chromatography card rotating unit 23 on chromatographic analysis instrument 2 in the present embodiment drives chromatography card 1 to be rotated with fixed angle,
The snap arm of chromatography card is set to be corresponding in turn to below sample results analytic unit, sample results analytic unit 22 can be one by one to layer
Each chromatography strip on analysis card 1 is read out analysis, realizes the continuous reading analysis to the different indexs of sample, greatly improves
During the efficiency of detection, and chromatographic analysis instrument rotation in the present embodiment, sample can be accelerated in chromatography card
Reaction time, therefore the present invention chromatographic analysis instrument shorten sample and chromatography card in chromatography strip between reaction time,
Detection efficiency is further increased, the present invention is more suitable for batch detection analysis.
Fig. 2 is the top view for chromatographing card rotating unit in the present embodiment, can be seen that the present embodiment is excellent by Fig. 1 and Fig. 2
Selection of land, chromatography card rotating unit 23 includes rotating mechanism, and the rotating mechanism includes stepper motor 3, is installed in the defeated of stepper motor 3
First bevel gear 4 on shaft and the second bevel gear 6 by the rolling assembling of fixing axle 5 in chromatograph lower casing 21, first
The axis of bevel gear 4 intersects with the axis of second bevel gear 6 on 90 ° of angles, and intermeshing transmission, the upper surface of second bevel gear 6
It is fixedly installed the chromatography for being provided with and being matched with the outer shape of chromatography card 1 in chromatography card mounting seat 7, the chromatography card mounting seat 7
Card mounting groove 71, above-mentioned chromatography card 1 is assembled in the chromatography card mounting groove 71, and the driving of stepper motor 3 first bevel gear 4 is rotated,
First bevel gear 4 drives second bevel gear 6 to rotate, and then drives chromatography card to be rotated.
Stepper motor in the present embodiment can also be replaced with common motor, can realize driving first bevel gear rotation
.
Certainly in other examples, above-mentioned rotating mechanism directly can also pass through its output shaft band by a motor
Dynamic chromatography card mounting seat is rotated, and realizes that chromatography card is rotated.
Embodiment two
Shown in Fig. 3 is the structural representation of the embodiment two for the chromatographic assay system that the present invention is provided, and Fig. 4 is Fig. 3
Top view.It can be seen that embodiment two and the difference of embodiment one are the chromatographic analysis instrument that embodiment two is provided by Fig. 3 and Fig. 4
Also include being used to that the chromatography card feed unit that card 1 is sent at the position of sample results analytic unit 22, and the second cone will to be chromatographed
The upper surface of gear 6 is not provided with mounting seat, and the chromatography card feed unit is arranged on the shell intracavitary of analyzer lower casing 21, the chromatography card
Feed unit includes feeding driving mechanism, transport mechanism, position-limit mechanism 35, and the feeding driving mechanism drives the transport mechanism to transport
Dynamic, the position-limit mechanism 35 limits the transmission position of the transport mechanism, and above-mentioned chromatography card rotating unit is also included when the chromatography card is passed
The bindiny mechanism for being connected the chromatography card with the chromatography card rotating unit when being sent to.
The present embodiment preferably, as shown in figure 3, the bindiny mechanism include be installed in chromatography card 1 deck body lower surface
Standard shaft, the clamping set 8 moved along standard shaft axis is equipped with by Telescopic spring elasticity on standard shaft, clamping covers 8 tops and is provided with
Buckling groove, clamping covers 8 bottoms and is provided with lower buckling groove, and the standard shaft being engaged by clamping with buckling groove on this is symmetrically arranged with the standard shaft
The axle sleeve 61 being fixedly connected with second bevel gear 6 is arranged with clamping projection 9, fixing axle 5, the outer peripheral face of axle sleeve 61 is symmetrically fixed
There is rotary clamping projection 62, the upper end of fixing axle 5, which is fixedly installed, determines magnetic coil 51, dynamic magnetic line is provided with clamping set 8
Circle 81, when chromatography card 1 is driven in place, the dynamic magnetic coil 81 determines the adhesive of magnetic coil 51 with this, and then drives lower buckling groove
It is engaged by clamping with rotary clamping projection 62, chromatography card is connected by now clamping set 8 with chromatography card rotating unit.
The present embodiment is it is further preferred that as shown in Figure 3 and Figure 4, the shell intracavitary of analyzer lower casing 21 is in transport mechanism
Upper end be installed with transmission guide rail 10, transmission guide rail 10 top be provided with installing plate 101, above-mentioned sample results analytic unit 22
It is arranged on the installing plate 101, the sample collection that information is gathered for sample results analytic unit 22 is provided with the installing plate 101
Window.
The present embodiment is it is further preferred that as shown in Figure 3 and Figure 4, feeding driving mechanism is above-mentioned stepper motor 3, should
Stepper motor 3 is arranged on the end of transmission guide rail 10, and transport mechanism includes what is be fixedly connected with the output shaft of the stepper motor 3
Sliding block 33, sliding block are fixedly installed on half gear 31, and the rack 32 with the engaged transmission of half gear 31, the rack 32
33 are slidably matched with transmission guide rail 10, are provided with sliding block 33 and cover 8 Double-ear-holes 34 passed through for clamping, and position-limit mechanism 35 is arranged on
Limit sensors are provided with the end of drive rail 10, position-limit mechanism 35.
The present embodiment it is further preferred that the present embodiment provide chromatographic analysis instrument also include control panel, the control panel with
Stepper motor 3, the limit sensors on position-limit mechanism 35, the electrical connection of sample results analytic unit.
Chromatography in other examples blocks preferred, is covered in its card and is further provided with information storage medium, should
Information storage medium is used for the information for storing chromatography strip and sample.
The course of work of embodiment two is：It first will need to detect that the chromatography strip of the different indexs of sample is put into chromatography card 1
Chromatography strip standing groove 114 in, sample then is added dropwise to sample slot 113, chromatography card 1 is put into sliding block 33, by control panel
Control stepper motor 3 is rotated forward, and drives half gear 31 to rotate forward and the engaged transmission of rack 32, and then with the sliding block 33 on carry-over bar 32
Feeding, when chromatography card 1 is fed into sample results 22 lower section of analytic unit, now the toothed portion of half gear 31 is point just and rack
32 engagements terminate, and position-limit mechanism 35 is spacing and will pass to control panel by signal in place by sliding block 33, and control panel is received will after signal
Determine magnetic coil 51 and dynamic magnetic coil 81 is powered, clamping set 8 is snapped fit onto in rotary clamping projection 62, and stepper motor 3 continues just
Turn, this hour rack is not in movement, and the driving of stepper motor 3 first bevel gear 4 is rotated, and then drives second bevel gear 6 to drive chromatography
Card 1 rotates freely two weeks, and then stepper motor 3 is inverted, and reversely rotates freely one week, makes in chromatography card 1 driving chromatography to block 1
Sample is fully reacted with chromatography strip, and now stepper motor 3 is rotated successively with certain step-length driving chromatography card with 90 ° of angles again, layer
The snap arm of one chromatography card 1 of the correspondence of sample results analytic unit 22 when analysis blocks 1 90 ° every turn, sample results analytic unit 22 passes through
Reading window 124 on snap arm lid 12 reads the reaction result of analysis chromatography strip, after the completion of four snap arm are all read, and control panel will
Determine magnetic coil 51 and dynamic magnetic coil 81 is powered off, clamping set 8 departs from rotary clamping projection 62 by the tensile force of spring reset
Return to initial position.Now stepper motor 3 continues to invert, and the toothed portion point of half gear 31 is just engaged again with rack 32,
Stepper motor continues to invert, and rack 32 is outwards transmitted with movable slider 33, will chromatograph card 1 and sends out, takes out and read analysis completion
Chromatography card, the chromatography card more renewed continues executing with above-mentioned steps.
In other examples, chromatography card feed unit can also chromatograph to drive sliding block to move by telescoping cylinder
Card rotating unit drives chromatography card to rotate by other drive mechanism such as stepper motor, and stepper motor can be sticked into first to chromatography
Row pre-rotation, makes the sample in chromatography card fully be reacted with chromatography strip, is driving chromatography card to be rotated according to certain angle, is making snap arm
Correspond to one by one below sample results analytic unit, be read out analysis.
In other examples, the structure of described bindiny mechanism has many forms to realize, such as chromatography is snapped into
Engaging tooth is provided with two joggle pieces engaged during position, a joggle piece, is provided with and is inserted for engaging tooth on another joggle piece
The engaging groove entered.
Embodiments of the invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this hair
The equivalent structure transformation that bright specification and accompanying drawing content are made, or other related technical fields are directly or indirectly used in,
It is included within the scope of the present invention.
Claims (6)
1. a kind of chromatographic assay system, including chromatography card and the chromatographic analysis instrument for reading the analysis chromatography card, it is special
Levy and be,
The Ka Gai that the chromatography card includes deck and is fastened on the deck；
The deck include deck body and be uniformly arranged on the outer peripheral face of the deck body at least two in radiation
The snap arm of shape distribution, the deck body is disposed on the same plane with the snap arm, and sample is provided with the deck body
The chromatography strip standing groove for the cell wall outer peripheral face for extending to the sample slot, the groove of the sample slot are provided with groove, the snap arm
The sample holes by the sample slot and the corresponding chromatography strip standing groove connection are offered on wall；
The Ka Gai includes the deck body cap coordinated with the deck body shape and is arranged on the deck body cap
With the snap arm lid of the snap arm form fit on outer peripheral face, it is provided with the deck body cap for being carried out to the sample slot
The well of sample-adding, the snap arm, which is covered, is provided with reading window；
The chromatographic analysis instrument includes analyzer lower casing；
Sample results analytic unit, is installed in the shell intracavitary of the chromatograph lower casing, and the reading covered by the snap arm
Window carries out digital independent analysis to the chromatography strip in the chromatography card；
Card rotating unit is chromatographed, the shell intracavitary of the analyzer lower casing is arranged on, and positioned at the sample results analytic unit
Lower section, the chromatography card rotating unit be used for drive it is described chromatography card with the horizontal circular-rotation of fixed angle, for the sample
This interpretation of result unit is read data one by one to the chromatography strip in the snap arm of the chromatography card；
The chromatographic analysis instrument also includes being used for being sent to the chromatography card chromatography card at sample results analytic unit position
Feed unit, the chromatography card feed unit is arranged on the shell intracavitary of the analyzer lower casing, the chromatography card feed unit
Including feeding driving mechanism, transport mechanism, position-limit mechanism, the feeding driving mechanism drives the transport mechanism motion, described
Position-limit mechanism limits the transmission position of the transport mechanism, and the chromatography card rotating unit is also included when the chromatography card is sent to
The bindiny mechanism for being connected the chromatography card with the chromatography card rotating unit during position, the bindiny mechanism is described including being installed in
Chromatograph and the card moved along standard shaft axis is equipped with by Telescopic spring elasticity on the standard shaft of the deck body lower surface of card, the standard shaft
Female connector, the clamping set top is provided with buckling groove, and the clamping set bottom is provided with lower buckling groove, the standard shaft symmetrically
It is provided with the standard shaft clamping being engaged by clamping with the upper buckling groove raised, rotary clamping is installed with the chromatography card rotating unit
Projection, the clamping, which is put, is provided with dynamic magnetic coil, in the upper of rotary clamping projection on the chromatography card rotating unit
Side, which is provided with, determines magnetic coil, and when the chromatography card is driven in place, the dynamic magnetic coil determines magnetic coil adhesive with described,
And then drive the lower buckling groove to be engaged by clamping with rotary clamping projection, now clamping set will chromatograph card and be rotated with chromatography card
Unit is connected.
2. chromatographic assay system according to claim 1, it is characterised in that the shell intracavitary of the analyzer lower casing is in institute
The upper end for stating transport mechanism is installed with above transmission guide rail, the transmission guide rail and is provided with installing plate, the sample results point
Analysis unit, which is arranged on the installing plate and then is arranged on the shell intracavitary of the chromatograph lower casing, the installing plate, to be provided with
The sample collection window of information is gathered for sample results analytic unit.
3. chromatographic assay system according to claim 2, it is characterised in that the feeding driving mechanism is stepper motor,
The stepper motor is arranged on the end of the transmission guide rail, and the transport mechanism includes the output shaft with the stepper motor
Sliding block is fixedly installed on half gear being fixedly connected, and the rack with the half gear engaged transmission, the rack,
The sliding block is slidably matched with the transmission guide rail, be provided with the sliding block for the standard shaft and clamping set through ears
Hole, the chromatography card rotating unit includes being fixedly installed on the stepper motor output shaft, and outside half gear
The first bevel gear of side, and by fixing axle rolling assembling on the analyzer lower house, and with the first bevel gear
The axle sleeve being fixedly connected with the second bevel gear, the rotation are arranged with the second bevel gear of engaged transmission, the fixing axle
Turn the outer peripheral face that clamping projection is installed in the axle sleeve, it is described to determine the upper end that magnetic coil is fixedly installed on the fixing axle.
4. chromatographic assay system according to claim 3, it is characterised in that the chromatographic analysis instrument also includes control panel,
The control panel is electrically connected with the stepper motor, position-limit mechanism, sample results analytic unit.
5. the chromatographic assay system according to any claim in Claims 1 to 4, it is characterised in that the chromatography card
Card cover the information storage medium for being provided with the information for storing chromatography strip and sample.
6. chromatographic assay system according to claim 5, it is characterised in that at the top of the deck body and the snap arm
Upper surface, which is provided with grafting boss, the grafting boss, is provided with spliced eye, and the card, which is covered, to be provided with and the spliced eye
The inserting column that correspondence grafting coordinates, the Ka Gai is inserted into the spliced eye by the inserting column and then is detachably fastened on
On the deck.
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| CN106405079A (en) * | 2016-11-18 | 2017-02-15 | 百奥森（江苏）食品安全科技有限公司 | Nine-link detection card for beta-incitant |
| CN107525924B (en) * | 2017-08-28 | 2019-04-23 | 青岛瑞思德生物科技有限公司 | A kind of autoimmune hepatic diseases antibody assay kit |
| CN110361528A (en) * | 2019-07-31 | 2019-10-22 | 苏州和迈精密仪器有限公司 | A kind of high throughput automated fluorescence immunity analyzer and its control method |
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