CN106053346A - 一种光片显微成像转换装置 - Google Patents
一种光片显微成像转换装置 Download PDFInfo
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- CN106053346A CN106053346A CN201610494150.1A CN201610494150A CN106053346A CN 106053346 A CN106053346 A CN 106053346A CN 201610494150 A CN201610494150 A CN 201610494150A CN 106053346 A CN106053346 A CN 106053346A
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- 238000003384 imaging method Methods 0.000 title claims abstract description 80
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 33
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- 230000013011 mating Effects 0.000 claims description 94
- 230000003287 optical effect Effects 0.000 claims description 13
- 238000006073 displacement reaction Methods 0.000 claims description 7
- 239000000523 sample Substances 0.000 abstract description 83
- 239000012472 biological sample Substances 0.000 abstract description 2
- 230000004048 modification Effects 0.000 abstract 1
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- 238000000799 fluorescence microscopy Methods 0.000 description 4
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- 238000010586 diagram Methods 0.000 description 3
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- 239000011521 glass Substances 0.000 description 2
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- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/10—Scanning
- G01N2201/103—Scanning by mechanical motion of stage
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- Biochemistry (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
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Claims (7)
Priority Applications (1)
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CN201610494150.1A CN106053346B (zh) | 2016-06-29 | 2016-06-29 | 一种光片显微成像转换装置 |
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CN201610494150.1A CN106053346B (zh) | 2016-06-29 | 2016-06-29 | 一种光片显微成像转换装置 |
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CN106053346A true CN106053346A (zh) | 2016-10-26 |
CN106053346B CN106053346B (zh) | 2018-06-08 |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106419889A (zh) * | 2016-10-31 | 2017-02-22 | 佛山科学技术学院 | 一种基于片层光的血流三维成像装置及方法 |
WO2020001529A1 (zh) * | 2018-06-27 | 2020-01-02 | 北京天天极因科技有限公司 | 用于透明化液滴成像的光片荧光显微成像装置及检测方法 |
CN111624758A (zh) * | 2020-06-04 | 2020-09-04 | 广州浩康生物科技有限公司 | 一种用于纳米材料转移的复合荧光显微系统 |
CN112198649A (zh) * | 2020-10-27 | 2021-01-08 | 南开大学 | 一种用于光片荧光显微镜的样品池放置台 |
US11814619B2 (en) | 2021-06-04 | 2023-11-14 | Enumerix, Inc. | Compositions, methods, and systems for single cell barcoding and sequencing |
US11834714B2 (en) | 2021-12-20 | 2023-12-05 | Enumerix, Inc. | Detection and digital quantitation of multiple targets |
US12000842B2 (en) | 2022-04-01 | 2024-06-04 | Enumerix, Inc. | Systems and methods for generating droplets and performing digital analyses |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN201177687Y (zh) * | 2007-09-18 | 2009-01-07 | 北京和众视野科技有限公司 | 显微样品旋转夹持器 |
CN103837513A (zh) * | 2014-02-20 | 2014-06-04 | 浙江大学 | 一种基于差分的光片照明显微方法和装置 |
US20140284461A1 (en) * | 2010-06-14 | 2014-09-25 | Howard Hughes Medical Institute | Bessel beam plane illumination microscope |
CN104204898A (zh) * | 2012-04-03 | 2014-12-10 | 圣安德鲁斯大学董事会 | 扩展容积的高分辨率成像 |
CN204422416U (zh) * | 2015-02-05 | 2015-06-24 | 向梅 | 非线性光学参数测量装置 |
CN105359025A (zh) * | 2013-07-10 | 2016-02-24 | 卡尔蔡司显微镜有限责任公司 | 用于光片显微技术的设备 |
CN205910111U (zh) * | 2016-06-29 | 2017-01-25 | 华中科技大学 | 一种光片显微成像转换装置 |
-
2016
- 2016-06-29 CN CN201610494150.1A patent/CN106053346B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN201177687Y (zh) * | 2007-09-18 | 2009-01-07 | 北京和众视野科技有限公司 | 显微样品旋转夹持器 |
US20140284461A1 (en) * | 2010-06-14 | 2014-09-25 | Howard Hughes Medical Institute | Bessel beam plane illumination microscope |
CN104204898A (zh) * | 2012-04-03 | 2014-12-10 | 圣安德鲁斯大学董事会 | 扩展容积的高分辨率成像 |
CN105359025A (zh) * | 2013-07-10 | 2016-02-24 | 卡尔蔡司显微镜有限责任公司 | 用于光片显微技术的设备 |
CN103837513A (zh) * | 2014-02-20 | 2014-06-04 | 浙江大学 | 一种基于差分的光片照明显微方法和装置 |
CN204422416U (zh) * | 2015-02-05 | 2015-06-24 | 向梅 | 非线性光学参数测量装置 |
CN205910111U (zh) * | 2016-06-29 | 2017-01-25 | 华中科技大学 | 一种光片显微成像转换装置 |
Non-Patent Citations (1)
Title |
---|
张刚平等: "快速宽场显微光切片成像技术分析及研究进展", <教育教学论坛> * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106419889A (zh) * | 2016-10-31 | 2017-02-22 | 佛山科学技术学院 | 一种基于片层光的血流三维成像装置及方法 |
CN106419889B (zh) * | 2016-10-31 | 2023-12-05 | 佛山科学技术学院 | 一种基于片层光的血流三维成像装置及方法 |
WO2020001529A1 (zh) * | 2018-06-27 | 2020-01-02 | 北京天天极因科技有限公司 | 用于透明化液滴成像的光片荧光显微成像装置及检测方法 |
CN111624758A (zh) * | 2020-06-04 | 2020-09-04 | 广州浩康生物科技有限公司 | 一种用于纳米材料转移的复合荧光显微系统 |
CN112198649A (zh) * | 2020-10-27 | 2021-01-08 | 南开大学 | 一种用于光片荧光显微镜的样品池放置台 |
US11814619B2 (en) | 2021-06-04 | 2023-11-14 | Enumerix, Inc. | Compositions, methods, and systems for single cell barcoding and sequencing |
US11834714B2 (en) | 2021-12-20 | 2023-12-05 | Enumerix, Inc. | Detection and digital quantitation of multiple targets |
US12000842B2 (en) | 2022-04-01 | 2024-06-04 | Enumerix, Inc. | Systems and methods for generating droplets and performing digital analyses |
Also Published As
Publication number | Publication date |
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CN106053346B (zh) | 2018-06-08 |
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Effective date of registration: 20240321 Address after: Room 1140, Qiantu Creative Space, Building B, 20th Floor, No. 628 Wuluo Road, Wuchang District, Wuhan City, Hubei Province, 430000, China Patentee after: Wuhan Sainz Instrument Equipment Co.,Ltd. Country or region after: Zhong Guo Address before: 430074 Hubei Province, Wuhan city Hongshan District Luoyu Road No. 1037 Patentee before: HUAZHONG University OF SCIENCE AND TECHNOLOGY Country or region before: Zhong Guo |