CN1060378C - Drop for otitis media - Google Patents

Drop for otitis media Download PDF

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Publication number
CN1060378C
CN1060378C CN97106071A CN97106071A CN1060378C CN 1060378 C CN1060378 C CN 1060378C CN 97106071 A CN97106071 A CN 97106071A CN 97106071 A CN97106071 A CN 97106071A CN 1060378 C CN1060378 C CN 1060378C
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China
Prior art keywords
tympanitis
ear drop
patients
treating
drop
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Expired - Fee Related
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CN97106071A
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CN1174049A (en
Inventor
朱文元
马宝坤
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Individual
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Individual
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Priority to CN97106071A priority Critical patent/CN1060378C/en
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Publication of CN1060378C publication Critical patent/CN1060378C/en
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Abstract

The present invention relates to an ear drop for treating tympanitis, which is characterized in that coptis, phellodendron bark, borneol and wine are used as raw materials, the raw materials are mixed according to a weight ratio and are filled in a container, wine is added into the container to be hermetically placed for 7 days, and the ear drop for treating tympanitis is obtained via filtration and slag removal. The ear drop for treating tympanitis has the advantages of simple medicine, good effect, special function, high exertion speed of medicine effect, high therapeutic effect and short therapeutic time, and is favorable for water evaporating, drying and scabbing wound surfaces. The ear drop for treating tympanitis has optimal effects on acute tympanitis, specifically mild patients are cured for one day, and severe patients are cured for two days. The ear drop for treating tympanitis has good therapeutic effects on patients having chronic tympanitis, and has slightly poor effects on patients having chronic tympanitis for more than 30 years.

Description

Drop for otitis media
The present invention relates to a kind of traditional Chinese medicine liquid for the treatment of otitis media.
In the prior art, application number is 93115515.0 patent application, discloses a kind of " otitis media specific remedy ".The prescription of organizing is: Rhizoma Chuanxiong, Radix Puerariae, Rhizoma Cimicifugae, Radix Salviae Miltiorrhizae, Rhizoma Polygonati, Shi Chang, Magnetitum, white peony root, Cortex Phellodendri, each 0.1g of Borax, Borneolum Syntheticum 0.25g, Rhizoma Coptidis 0.05g, Rhizoma Drynariae 0.01-0.14g, Moschus 0.01-0.07g, thunder skin Rule 0.01-0.05g, Oleum Juglandis 10cc.Wherein Oleum Juglandis is a solvent, and other medicines all are ground into medicated powder.Get Oleum Juglandis and mix thoroughly, be coated with the affected part after leaving standstill first quarter moon.There is following defective in this prescription:
The first is too numerous and diverse because of used Chinese medicine, and expense is higher, and especially the in great shortage Moschus in medicine source costs an arm and a leg.
It two is to substitute glycerol with Oleum Juglandis to make solvent, and it remains oily matter.Make solvent with oil, poor permeability is unfavorable for invading out of active ingredient, has hindered the evaporation of wound surface moisture content after smearing, so influenced the dry and incrustation of wound surface.
It three is that the performance of drug effect is also slowly inevitable, certainly will cause the prolongation of treatment time because the active ingredient of medicine is slowly to immerse in the oil-based solvent.
It four is that to play Rhizoma Coptidis, Cortex Phellodendri, its content of Borneolum Syntheticum of key drugs with function as the treatment otitis media extremely low.Higher limit in this prescription is 10.86 grams (wherein the weight of Oleum Juglandis is pressed proportion 0.93 calculating), and lower limit is 10.63 grams.Rhizoma Coptidis is that the 0.46-0.47% of gross weight, 0.29-0.94%, the Borneolum Syntheticum that Cortex Phellodendri is gross weight are the 2.3-2.35% of gross weight.So low content is made solvent with the oily matter of poor permeability again, is difficult to the performance better therapeutic effect.
The objective of the invention is that to disclose a kind of prescription simple, cheap, help active ingredient invades out to people, drip the water evaporates that helps wound surface behind the ear, drying, incrustation, curative effect height, the drug effect performance is fast, treatment time is short Drop for otitis media.
The present invention realizes by following proposal.
Prescription (parts by weight):
Rhizoma Coptidis 8-20
Cortex Phellodendri 8-20
Borneolum Syntheticum 0.6-2.0
Chinese liquor 30-100
The production method of Drop for otitis media is:
Rhizoma Coptidis, Cortex Phellodendri are through pulverizing or all can without pulverizing.Rhizoma Coptidis, Cortex Phellodendri, Borneolum Syntheticum are placed in the hermetic container, add 50 degree high quality liquors, soak 7 days after-filtration and remove slag, gained liquid is Drop for otitis media.
Be monarch with the Rhizoma Coptidis heat-clearing and toxic substances removing in the prescription, the evacuation of pus of Cortex Phellodendri dampness is a minister, and the hot perfume (or spice) of Borneolum Syntheticum is walked to scurry removing the necrotic tissue and promoting granulation and is assistant, and Chinese liquor blood circulation promoting and blood stasis dispelling, dispelling toxins and dredging collaterals, anti-inflammatory analgetic are for making.
Though herbal species used in the prescription of Drop for otitis media is few, selectivity is strong, the function speciality, and the medicine letter is imitated grand.The higher limit of the parts by weight of Rhizoma Coptidis, Cortex Phellodendri, Borneolum Syntheticum, Chinese liquor is 142 in the prescription, lower limit is 46.6.Wherein Rhizoma Coptidis accounts for the 14.1-17.2% of gross weight, and Cortex Phellodendri accounts for the 14.1-17.2% of gross weight, and Borneolum Syntheticum accounts for the 1.3-1.4% of gross weight, and Chinese liquor accounts for the 64.4-70.4% of gross weight.Wherein Rhizoma Coptidis, Cortex Phellodendri be higher than Rhizoma Coptidis in the documents, Cortex Phellodendri content 18.30-18.33 doubly, Borneolum Syntheticum is higher than 1.4-1.5 doubly.
In the Drop for otitis media prescription, Chinese liquor is not only as solvent, has also replaced the effect of some drugs in the documents simultaneously.The one, the function of promoting blood circulation to disperse blood clots of replacement Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, white peony root; The 2nd, the function of the dispelling toxins and dredging collaterals of replacement Radix Puerariae, Rhizoma Cimicifugae, Rhizoma Polygonati, Shi Chang, phosphorus stone, Borax; The 3rd, Chinese liquor itself also has anti-corrosion function, thereby has replaced the effect in Moschus, thunder skin Rule.Full side composition has the function of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, dampness evacuation of pus, putrefaction-removing granulation-promoting.
Earlier washes auditory meatus with hydrogen peroxide before the treatment, clean with disinfecting cotton swab, make then and suffer from ear upwards, splash into medicinal liquid 3-5 and drip, sitting up with the sterilized cotton ball ear plug after lying on one's side 5 minutes gets final product, and drips every day twice.Acute otitis media was cured in one day, and chronic otitis media was cured in three days, and is poor slightly to suffering from the old people effect of chronic otitis media more than 30 years.
Confirm that by the clinical experiment statistical data Drop for otitis media reaches 90% to the cure rate of treatment acute-chronic purulent otitis media, effective percentage reaches 96%, and the matched group cure rate reaches 12%, and effective percentage reaches 76%, this shows, the treatment group obviously is better than matched group.See the following form.
Total routine number Recovery from illness Produce effects Effectively Invalid Obvious effective rate Effective percentage
The treatment group 100 90(90%) 4(4%) 2(2%) 4(4%) 94% 96%
Matched group 50 6(12%) 10(20%) 22(44%) 12(24%) 32% 76%
The otitis media dropping liquid drips the water evaporates that helps wound surface behind the ear, keeps the drying of wound surface, therefore incrustation is fast, and healing process is short, and speed is fast.With Chinese liquor do solvent not only adaptability strong, have no side effect, do not have any contraindication, any age all can be used, and cheap, be easy to get.
Below in conjunction with embodiment in detail the present invention is described in detail.
Embodiment 1
Prescription: (parts by weight)
Rhizoma Coptidis 8
Cortex Phellodendri 8
Borneolum Syntheticum 0.6
Chinese liquor 30
Rhizoma Coptidis, Cortex Phellodendri, Borneolum Syntheticum are packed in the container, add 50 degree high quality liquors, under air-tight state, placed 7 days, filter and remove residue then, gained liquid is Drop for otitis media.
Embodiment 2
Prescription (parts by weight)
Rhizoma Coptidis 20
Cortex Phellodendri 20
Borneolum Syntheticum 2
Chinese liquor 100
Preparation method is with embodiment 1.
Embodiment 3
Prescription (parts by weight)
Rhizoma Coptidis 9-15
Cortex Phellodendri 9-15
Borneolum Syntheticum 0.8-1.5
Chinese liquor 40-80
Preparation method is with embodiment 1,2.
Embodiment 4 (most preferred embodiment)
Prescription: (parts by weight)
Rhizoma Coptidis 10
Cortex Phellodendri 10
Borneolum Syntheticum 1
Chinese liquor 50
Preparation method is with embodiment 1,2,3.

Claims (1)

1. Drop for otitis media for the treatment of otitis media is characterized in that: it is that raw material by the following weight ratio is prepared into liquid preparation according to a conventional method:
Rhizoma Coptidis 8-20 Cortex Phellodendri 8-20
Borneolum Syntheticum 0.6-20 Chinese liquor 30-100.
CN97106071A 1997-08-29 1997-08-29 Drop for otitis media Expired - Fee Related CN1060378C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN97106071A CN1060378C (en) 1997-08-29 1997-08-29 Drop for otitis media

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Application Number Priority Date Filing Date Title
CN97106071A CN1060378C (en) 1997-08-29 1997-08-29 Drop for otitis media

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CN1174049A CN1174049A (en) 1998-02-25
CN1060378C true CN1060378C (en) 2001-01-10

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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098080C (en) * 1999-06-09 2003-01-08 安徽医科大学第一附属医院 Ear drops
CN101766722B (en) * 2009-01-05 2012-11-28 生春堂制药工业股份有限公司 Spray formula with slough-eliminating and granulation-promoting effects
CN102274329A (en) * 2011-07-26 2011-12-14 廉威虎 Medicine for treating hemorrhoids and preparation method thereof
CN103100024B (en) * 2012-12-11 2014-07-02 余金标 Drug for treating otitis media suppurative
CN103989789B (en) * 2014-05-29 2016-06-22 高广忠 A kind of Chinese medicine dropping treating otitis media and preparation method thereof
CN104840756A (en) * 2015-06-02 2015-08-19 岳兵兵 Drops for treating acute otitis media and preparation method thereof
CN110772570A (en) * 2019-11-01 2020-02-11 河南一付良方健康科技有限公司 Traditional Chinese medicine formula for treating otitis media and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1069197A (en) * 1992-08-04 1993-02-24 许万山 Control preparation of otitis media new drug and application process
CN1077116A (en) * 1993-04-01 1993-10-13 李恕辉 The externally-applied powder and the manufacture method of treatment otitis media

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1069197A (en) * 1992-08-04 1993-02-24 许万山 Control preparation of otitis media new drug and application process
CN1077116A (en) * 1993-04-01 1993-10-13 李恕辉 The externally-applied powder and the manufacture method of treatment otitis media

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
中医杂志1984,25(8) 1984.8.31 王可进,岵黄滴耳油治疗化脓性中耳炎 *
四川中医1992,10(7) 1992.7.31 席承权,黄连滴耳油治疗中耳炎50例 *
湖北中医杂志1984(4) 1984.4.30 李俊华,二黄滴耳油治疗中耳炎 *
湖北中医杂志1984(4) 1984.4.30 李俊华,二黄滴耳油治疗中耳炎;四川中医1992,10(7) 1992.7.31 席承权,黄连滴耳油治疗中耳炎50例;中医杂志1984,25(8) 1984.8.31 王可进,岵黄滴耳油治疗化脓性中耳炎 *

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