CN1060375C

CN1060375C - Traditional Chinese medicinal preparation for curing psoriasis

Info

Publication number: CN1060375C
Application number: CN97105795A
Authority: CN
Inventors: 刘文江
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-04-08
Filing date: 1997-04-08
Publication date: 2001-01-10
Anticipated expiration: 2017-04-08
Also published as: CN1195537A

Abstract

The present invention relates to a psoriasis treating Chinese medicinal preparation which is an oral medicament with various preparations and is prepared from the following Chinese medicinal raw materials by a common method:10 to 20g of coptis, 10 to 20g of baikal skullcap, 10 to 20g of yellow-corktree bark, 10 to 20g of radix isatidis, 10 to 20g of safflower, 10 to 20g of brownishpurple aspidistra root, 10 to 20g of cicada molting, 10 to 30g of angelica, 10 to 30g of day lily, 10 to 20g of rehmannia root, 10 to 30g of rhubarb, 10 to 40g of garter snake, 10 to 30g of glabrous greenbrier rhizome, 10 to 20g of honeycomb and 5 to 10g of radix glycyrrhiza. The psoriasis treating Chinese medicinal preparation has the advantages of good therapeutic effect, fast effect, relapse resistance, no toxic effect and no side effect.

Description

The psoriatic Chinese medicine preparation of a kind of treatment

The present invention relates to the psoriatic Chinese medicine preparation of a kind of treatment.

Psoriasis is a kind of chronic dermatosis of obstinate refractory common, that easily recur, the general instant effect of western medicine, but relapse rate height, and side effect is big, and the treatment by Chinese herbs method is also arranged, and has effect to some extent.

The purpose of this invention is to provide the psoriatic pure Chinese medicinal preparation of a kind of treatment, not only curative effect height, and instant effect, anti-recurrence has no side effect.

Chinese medicine preparation of the present invention, in parts by weight, be by Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri each 10～20, Radix Isatidis 10～20, Flos Carthami 10～20, Periostracum Serpentis, Periostracum Cicadae 10～20, Radix Angelicae Sinensis, Hemerocallis citrina Baroni each 10～30, the oral Chinese medicine of the various dosage forms made by usual way medically for raw material of Chinese medicine of the Radix Rehmanniae 10～20, Radix Et Rhizoma Rhei 10～30, Zaocys 10～40, Rhizoma Smilacis Glabrae 10～30, Nidus Vespae 10～20, Radix Glycyrrhizae 5～10.

Have stupid poison according to psoriasis and meet the flesh natural fibre line of meat deeply, the pathogenic characteristic that the difficult difficulty of loosing is removed, emphasis selects treating the poisonous disease with poisonous drugs, clearing away heat and cooling blood for use, dispel the wind moisturize, the above-mentioned Chinese medicine of nourshing blood and promoting blood circulation, have promoting blood circulation, remove immune complex, improve immunologic function, regulate the body's immunity balance, anti-recurrence, characteristics such as have no side effect, through clinical observation treatment for many years and follow up a case by regular visits to, effective percentage reaches more than 92%, cure rate reaches more than 78.5%, instant effect, anti-recurrence, long-term effect are good, can reach the purpose of radical cure.

Below exemplify Comparison of therapeutic:

1, case data:

Select psoriatic's 500 examples of treatment in the recent period, wherein male 400 examples, women 100 examples, 6～58 years old age, the course of disease 10 days to 20 years.160 similar patients of alternative condition are matched group, male 80 examples, women 80 examples, 8～60 years old age, the course of disease 1 month to 25 years.

2, Therapeutic Method:

The treatment group is taken capsule formulation of the present invention (No. 0 a capsule) twice-daily, and each 10, oral to serve on January be a course of treatment, and general 1～3 course of treatment, matched group is taken the bimolane capsule.

3, criterion of therapeutical effect and result:

Skin lesion or pruritus are all or 90% disappear and be that it 50～90% is effective that recovery from illness, skin lesion or pruritus disappear.Invalidly be one course of treatment of treatment, skin lesion disappearance less than 50% or do not have obvious changer.

The group example	The example number	Recovery from illness	Effectively	Invalid	Effective percentage %
The group example	The example number	Recovery from illness	Effectively	Invalid	Effective percentage %	The treatment group	500	380	80	40	92
Matched group	160	20	60	80	50	The treatment group	500	380	80	40	92

The treatment group has been compared significant differences (X with matched group ²=8%, P＜0.01), before and after the treatment highly significant difference (t=4.97, P＜0.01) is arranged all, have a blood test after the treatment, urine, stool routine, hepatic and renal function, IgG, IgM, IgA and lymphocyte transformation do not have obvious change.

Case one:

Chen Ying, woman, 64 years old.

History of present illness: after the several years cause is suffered from acute pharyngitis, find that red rash appears in trunk, do not note at that time, increased gradually afterwards, and there is white scales on the surface, pruritus is obvious, once be acute psoriasis at Beijing hospital diagnosis, through many Western medicine, Chinese medicine " KEYIN PIAN " the treatment half a year commentaries on classics of not getting better, general whole body of skin lesion, I treated afterwards.

Check: general medicine is checked no abnormality seen, department of dermatologry is checked in the hair, trunk, general big red grouper of highgrain grain of extremity, the silvery white squama that surface attachment is thin, luminous under the moonlight, the infiltration that takes on a red color of obvious blush, its end is arranged, after squama is peeled off by force around the squama, visible petechia, bottom surface, lower limb skin lesion partial fusion is in blocks.

Western medicine diagnose: psoriasis is carried out the phase.

Differential diagnosis in tcm: blood-heat type psoriasis.

Take capsule of the present invention skin lesion 65% after course of treatment, disappear substantially, after add 2 courses of treatment, all skin lesion, pruritus, squama disappear, not recurrence in 5 years is followed up a case by regular visits in recovery from illness.

Case 2:

Lee X, the man, 38 years old, people from Linyi, I go to a doctor over 90 years.

The main suit: head and trunk, extremity play erythema, and sheet takes off white scales, year surplus in the of ten.

History of present illness: before surplus in the of ten year overhead portion the minority speckle appears, the silvery white squama of loam cake, later erythra increases gradually, merge in flakes, cover the full crown, play is itched, once at Shandong Province's hospital admission, be diagnosed as " psoriasis ", and used multiple medicine all not cure, still stay the minority erythra, same erythra appearred in extremity in 90 years, treated at me, and thing is not all cured, still stay the minority erythra, same erythra appearred in extremity in 90 years, treated at me, came the previous moon of institute at breast, abdomen, the back has most erythra to occur, and be fused into sheet mutually, also constantly have new erythra to occur simultaneously, the Etretinate electuary was taken in inquiring in the past, do not heal, recurrence comes me to treat.

Check: ordinary circumstance is fair, and internal medicine is checked Non Apparent Abnormality, and the full crown covers silvery white squama, silver bits shape cloudlike, sheet comes off, trunk, extremity all have big as YUQIAN, little erythra as syringe needle, squama are adhered in blocks than approaching partial fusion.

Western medicine diagnose: psoriasis resting stage.

Tcm diagnosis: blood-dryness type.

The capsule recovery from illness of the present invention 2 courses of treatment that doses a patient with, but local a small amount of skin lesion is taken the recovery from illness course of treatment again, follows up a case by regular visits to not recurrence in 6 years.

Case three:

Zhao X, the man, 43 years old, people from Zichuan District, on November 26th, 92 came me to go to a doctor.

The main suit: the general rubescent speckle of whole body played pustule 4 years.

History of present illness: found that erythema appearred in ancon in 1986, pustule has squama, the time heavy when light, failed at that time to clarify a diagnosis, in August, 89, general trunk, extremity were lived certain hospital at that time, be diagnosed as pustular psoriasis, once used " histotherapy ", " intramuscular injection " VitB12, oral prednisone, external mustard gas ointment, take medicines such as second imonium, the commentaries on classics of not getting better comes me to treat.

Check: extremity, trunk erythema squama, on indivedual erythra pustule is arranged, duplex portion, chest erythra merge in flakes, and silvery white squama is thicker, and the substrate flushing soaks into obviously, and the fingernail distortion of two backs has thimble to refer to.

Western medicine diagnose: pustule type psoriasis.

Tcm diagnosis: disorder of QI and blood, accumulate in warm.

Give oral capsule of the present invention and disappear after three courses of treatment, follow up a case by regular visits to so far not recurrence.

Embodiment one:

Rhizoma Coptidis 10g, Radix Scutellariae 10g, Cortex Phellodendri 10g, Radix Isatidis 10g, Flos Carthami 10g, Periostracum Serpentis 10g, Periostracum Cicadae 10g, Radix Angelicae Sinensis 10g, Hemerocallis citrina Baroni 10g, Radix Rehmanniae 10g, Radix Et Rhizoma Rhei 10g, Zaocys 10g, Rhizoma Smilacis Glabrae 10g, Nidus Vespae 10g, Radix Glycyrrhizae 5g.

Make capsule by the common capsule preparation method of medical science

Embodiment two:

Rhizoma Coptidis 15g, Radix Scutellariae 13g, Cortex Phellodendri 15g, Radix Isatidis 16g, Flos Carthami 14g, Periostracum Serpentis 15g, Periostracum Cicadae 14g, Radix Angelicae Sinensis 15g, Hemerocallis citrina Baroni 15g, Radix Rehmanniae 15g, Radix Et Rhizoma Rhei 14g, Zaocys 20g, Rhizoma Smilacis Glabrae 18g, Nidus Vespae 15g, Radix Glycyrrhizae 7g.

Make pill by the common pill manufacture method of medical science.

Embodiment three:

Rhizoma Coptidis 18g, Radix Scutellariae 18g, Cortex Phellodendri 18g, Radix Isatidis 18g, Flos Carthami 17g, Periostracum Serpentis 16g, Periostracum Cicadae 17g, Radix Angelicae Sinensis 20g, Hemerocallis citrina Baroni 20g, Radix Rehmanniae 17g, Radix Et Rhizoma Rhei 20g, Zaocys 30g, Rhizoma Smilacis Glabrae 23g, Nidus Vespae 18g, Radix Glycyrrhizae 9g.

Make electuary by the common electuary manufacture method of medical science.

Embodiment four:

Rhizoma Coptidis 19g, Radix Scutellariae 19g, Cortex Phellodendri 19g, Radix Isatidis 19g, Flos Carthami 19g, Periostracum Serpentis 18g, Periostracum Cicadae 19g, Radix Angelicae Sinensis 25g, Hemerocallis citrina Baroni 25g, Radix Rehmanniae 19g, Radix Et Rhizoma Rhei 27g, Zaocys 35g, Rhizoma Smilacis Glabrae 27g, Nidus Vespae 19g, Radix Glycyrrhizae 8g.

Make capsule by the common capsular manufacture method of medical science.

Embodiment five:

Rhizoma Coptidis 20g, Radix Scutellariae 19g, Cortex Phellodendri 20g, Radix Isatidis 18g, Flos Carthami 20g, Periostracum Serpentis 19g, Periostracum Cicadae 20g, Radix Angelicae Sinensis 28g, Hemerocallis citrina Baroni 28g, Radix Rehmanniae 20g, Radix Et Rhizoma Rhei 29g, Zaocys 38g, Rhizoma Smilacis Glabrae 29g, Nidus Vespae 20g, Radix Glycyrrhizae 9g.

Manufacture method by the common pill of medical science is made pill.

Embodiment six:

Rhizoma Coptidis 20g, Radix Scutellariae 20g, Cortex Phellodendri 20g, Radix Isatidis 20g, Flos Carthami 20g, Periostracum Serpentis 20g, Periostracum Cicadae 20g, Radix Angelicae Sinensis 30g, Hemerocallis citrina Baroni 30g, Radix Rehmanniae 20g, Radix Et Rhizoma Rhei 30g, Zaocys 40g, Rhizoma Smilacis Glabrae 30g, Nidus Vespae 20g, Radix Glycyrrhizae 10g.

Make capsule by the common capsular manufacture method of medical science.

Embodiment seven:

Rhizoma Coptidis 10g, Radix Scutellariae 12g, Cortex Phellodendri 18g, Radix Isatidis 15g, Flos Carthami 20g, Periostracum Serpentis 20g, Periostracum Cicadae 20g, Radix Angelicae Sinensis 15g, Hemerocallis citrina Baroni 15g, Radix Rehmanniae 10g, Radix Et Rhizoma Rhei 30g, Zaocys 30g, Rhizoma Smilacis Glabrae 15g, Nidus Vespae 20g, Radix Glycyrrhizae 5g.

Make capsule by the common capsular manufacture method of medical science.

Claims

1, the psoriatic Chinese medicine preparation of a kind of treatment, it is characterized in that: in parts by weight, by Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri each 10～20, Radix Isatidis 10～20, Flos Carthami 10～20, Periostracum Serpentis, Periostracum Cicadae each 10～20, Radix Angelicae Sinensis, Hemerocallis citrina Baroni each 10～30, the oral medicine of the various dosage forms made by usual method for raw material of Chinese medicine of the Radix Rehmanniae 10～20, Radix Et Rhizoma Rhei 10～30, Zaocys 10～40, Rhizoma Smilacis Glabrae 10～30, Nidus Vespae 10～20, Radix Glycyrrhizae 5～10.