CN106030278A - 分散在液相中的蛋白质的拉曼光谱结构调查研究 - Google Patents

分散在液相中的蛋白质的拉曼光谱结构调查研究 Download PDF

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Publication number
CN106030278A
CN106030278A CN201580008189.1A CN201580008189A CN106030278A CN 106030278 A CN106030278 A CN 106030278A CN 201580008189 A CN201580008189 A CN 201580008189A CN 106030278 A CN106030278 A CN 106030278A
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China
Prior art keywords
sample
raman
protein
spectral
detector
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CN201580008189.1A
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English (en)
Chinese (zh)
Inventor
E·尼尔·刘易斯
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Malvern Panalytical Ltd
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Malvern Instruments Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/006—Determining flow properties indirectly by measuring other parameters of the system
    • G01N2011/008—Determining flow properties indirectly by measuring other parameters of the system optical properties

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201580008189.1A 2014-03-25 2015-03-25 分散在液相中的蛋白质的拉曼光谱结构调查研究 Pending CN106030278A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461970198P 2014-03-25 2014-03-25
US61/970,198 2014-03-25
US201462026563P 2014-07-18 2014-07-18
US62/026,563 2014-07-18
PCT/GB2015/050892 WO2015145149A1 (en) 2014-03-25 2015-03-25 Raman spectroscopic structure investigation of proteins dispersed in a liquid phase

Publications (1)

Publication Number Publication Date
CN106030278A true CN106030278A (zh) 2016-10-12

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580008189.1A Pending CN106030278A (zh) 2014-03-25 2015-03-25 分散在液相中的蛋白质的拉曼光谱结构调查研究

Country Status (5)

Country Link
US (1) US20180180549A1 (enExample)
EP (1) EP3123150A1 (enExample)
JP (1) JP2017512999A (enExample)
CN (1) CN106030278A (enExample)
WO (1) WO2015145149A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107132209A (zh) * 2017-04-28 2017-09-05 南京理工大学 一种基于纳米银/氧化石墨烯/氯化钠的拉曼增强基底免标记检测牛血清蛋白的方法

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* Cited by examiner, † Cited by third party
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CN109063413B (zh) * 2018-06-07 2021-04-06 浙江工业大学 一种群体爬山迭代蛋白质构象空间优化方法
IL280880B2 (en) * 2018-08-27 2025-04-01 Regeneron Pharma Using Raman Spectroscopy in Downstream Purification
US11698304B2 (en) * 2019-02-15 2023-07-11 Wayne State University Apparatuses, systems, and methods for detecting materials based on Raman spectroscopy
CN111474133B (zh) * 2020-03-31 2023-06-06 上海理工大学 检测胎盘素里黄体酮和雌酮两种激素的方法
FR3112856B1 (fr) * 2020-07-27 2022-11-11 Univ Grenobles Alpes Procede de determination des parametres rheologiques d’un fluide
CN114199852B (zh) * 2021-12-07 2024-03-01 天津大学 一种药物共晶性能的表征方法

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CN1910439A (zh) * 2004-01-23 2007-02-07 贝克曼考尔特公司 多激光器触发系统和方法
US20100211329A1 (en) * 2007-10-12 2010-08-19 Stuart Farquharson Method and apparatus for determining properties of fuels
EP2343117A2 (en) * 2004-01-14 2011-07-13 Chevron Phillips Chemical Company Lp Method and apparatus for monitoring polyolefin production
WO2012037430A1 (en) * 2010-09-17 2012-03-22 Abbott Laboratories Raman spectroscopy for bioprocess operations

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US7107092B2 (en) * 2000-08-21 2006-09-12 The General Hospital Corporation Methods for diagnosing a neurodegenerative condition
US6875973B2 (en) * 2000-08-25 2005-04-05 Amnis Corporation Auto focus for a flow imaging system
US6961599B2 (en) * 2001-01-09 2005-11-01 Childrens Hospital Los Angeles Identifying or measuring selected substances or toxins in a subject using resonant raman signals
US20060023219A1 (en) * 2001-03-28 2006-02-02 Meyer Michael G Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
DE10121999A1 (de) * 2001-05-05 2002-11-07 Merck Patent Gmbh Verfahren und Vorrichtung zur Bestimmung von flüchtigen Substanzen in Lösung
WO2005009236A1 (en) * 2003-07-31 2005-02-03 Koninklijke Philips Electronics N.V. Method and apparatus for determining a property of a fluid which flows through a biological tubular structure with variable numerical aperture
WO2006033962A2 (en) * 2004-09-20 2006-03-30 Wisconsin Alumni Research Foundation Nonlinear spectroscopic methods for identifying and characterizing molecular interactions
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US7920261B2 (en) * 2008-02-11 2011-04-05 Massachusetts Institute Of Technology Method and apparatus for detecting and discriminating particles in a fluid
JP2012507283A (ja) * 2008-10-31 2012-03-29 バイオメリュー・インコーポレイテッド ラマン分光法を使用した微生物の分離、キャラクタリゼーションおよび／または同定方法
WO2011088580A1 (en) * 2010-01-22 2011-07-28 British Columbia Cancer Agency Branch Apparatus and methods for characterization of lung tissue by raman spectroscopy
US20150038347A1 (en) * 2010-03-19 2015-02-05 The University of Wyoming,an institution of higher of the State of Wyoming Surface enhanced raman spectroscopy
WO2011116402A2 (en) * 2010-03-19 2011-09-22 University Of Wyoming, An Institution Of Higher Education Of The State Of Wyoming Surface enhanced raman spectroscopy
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WO2013027034A1 (en) * 2011-08-19 2013-02-28 Malvern Instruments Limited Dual-mode characterization of particulates

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0751388A2 (en) * 1995-06-28 1997-01-02 Kyoto Dai-ichi Kagaku Co., Ltd. Method of optically measuring a component in solution
CN1114098C (zh) * 1995-06-28 2003-07-09 株式会社京都第一科学 溶液中成分的光学测定方法
EP2343117A2 (en) * 2004-01-14 2011-07-13 Chevron Phillips Chemical Company Lp Method and apparatus for monitoring polyolefin production
CN1910439A (zh) * 2004-01-23 2007-02-07 贝克曼考尔特公司 多激光器触发系统和方法
US20100211329A1 (en) * 2007-10-12 2010-08-19 Stuart Farquharson Method and apparatus for determining properties of fuels
WO2012037430A1 (en) * 2010-09-17 2012-03-22 Abbott Laboratories Raman spectroscopy for bioprocess operations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107132209A (zh) * 2017-04-28 2017-09-05 南京理工大学 一种基于纳米银/氧化石墨烯/氯化钠的拉曼增强基底免标记检测牛血清蛋白的方法

Also Published As

Publication number Publication date
EP3123150A1 (en) 2017-02-01
JP2017512999A (ja) 2017-05-25
US20180180549A1 (en) 2018-06-28
WO2015145149A1 (en) 2015-10-01

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Application publication date: 20161012