CN105999027A - Sheep liver powder and preparation method and application thereof - Google Patents

Sheep liver powder and preparation method and application thereof Download PDF

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Publication number
CN105999027A
CN105999027A CN201610394862.6A CN201610394862A CN105999027A CN 105999027 A CN105999027 A CN 105999027A CN 201610394862 A CN201610394862 A CN 201610394862A CN 105999027 A CN105999027 A CN 105999027A
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parts
powder
liver powder
lamb liver
preparation
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郝珍珠
李国强
李民强
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

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Abstract

The invention discloses a sheep liver powder, and belongs to the field of Chinese patent medicines. The sheep liver powder is mainly prepared from the following raw material medicines in parts by weight: 1-2 parts of sheep livers, 1-2 parts of white atractylodes rhizome, 1-2 parts of white hyacinth bean, 3-5 parts of fructus amomi, 1-2 parts of magnolia obavata, 5-8 parts of aloe, 1-2 parts of poria cocos from Yunnan of China, 1-3 parts of beeswax, and 1-2 parts of hawthorn. The invention also discloses a preparation method of the sheep liver powder and an application of the sheep liver powder in treatment of stomach diseases. The sheep liver powder provided by the invention has significant efficacies on stomach pain, excess gastric acid, hiccups, heartburn, abdominal distension, diarrhea, perennial diarrhea, facial scourge jaundice, apocleisis and other symptoms caused by superficial gastritis, erosive gastritis, gastroptosis, gastric ulcer and other stomach diseases.

Description

A kind of lamb liver powder and its preparation method and application
Technical field
The invention belongs to technical field of Chinese patent medicine, be specifically related to a kind of lamb liver powder and its preparation method and application.
Background technology
Gastropathy, is many general designations with stomach relevant disease.They have similar symptom, as uncomfortable in upper abdomen gastral cavilty portion, pain Bitterly, the most glutted, belch, return acid, even Nausea and vomiting etc..The most common gastropathy has acute gastritis, chronic stomach Inflammation, gastric ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric calculus, the innocent and malignant tumour of stomach, also There are prolapse of gastric mucosa, acute gastric dilatation, pyloric obstruction etc..Patient once suffers from gastropathy, not only can affect stomach healthy, stomach Disease also can affect otherwise health by affecting the diet of patient.
Existing Chinese medicinal formulae has utilize lamb liver powder to treat disease of stomach, but tradition lamb liver powder production technology numerous Trivial, to go out production life cycle long, the products taste generated is poor, curative effect general, even patient tradition lamb liver powder to be produced rejection existing As, it is difficult to lamb liver powder traditional under clothes.
Summary of the invention
It is an object of the invention to provide a kind of lamb liver powder, it is provided that corresponding preparation method and application are then another of the present invention Individual purpose.
Based on above-mentioned purpose, the present invention by the following technical solutions: a kind of lamb liver powder, mainly by the raw material of following weight parts Medicine is prepared from: Hepar Caprae seu ovis 1~2 parts, the Rhizoma Atractylodis Macrocephalae 1~2 parts, Semen Lablab Album 1~2 parts, Fructus Amomi 3~5 parts, Cortex Magnoliae Officinalis 1~2 parts, Aloe 5~8 parts, Poria 1~2 parts, Cera Flava 1~3 parts, Fructus Crataegi 1~2 parts.
Preferably, a kind of lamb liver powder, mainly it is prepared from by the crude drug of following weight parts: Hepar Caprae seu ovis 2 parts, the Rhizoma Atractylodis Macrocephalae 1 Part, Semen Lablab Album 1 part, Fructus Amomi 3 parts, Cortex Magnoliae Officinalis 1 part, Aloe 5 parts, Poria 1 part, 3 parts of Cera Flava, Fructus Crataegi 1 part.
Preferably, the dosage form of lamb liver powder is powder.
The preparation method of above-mentioned lamb liver powder, comprises the following steps:
(1) Hepar Caprae seu ovis section is dried;
(2) by the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Amomi, Cortex Magnoliae Officinalis, Poria, Fructus Crataegi, Hepar Caprae seu ovis mixing, medicated powder is pulverized to obtain;
(3) by the medicated powder of step (2) gained with Aloe powder mixing, add water stirring, after then medicated powder and Aloe powder being made bolus, 1-is steamed 2 hours, dry;
(4) step (3) gained medicine is mixed homogeneously with the Cera Flava after heating and melting i.e. obtain lamb liver powder.
Further, after Aloe intense fire heating, drying is reduced to original 1/3rd to weight, then with step (2) gained Medicated powder mixing.
Further, in step (2), the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Crataegi first carry out parch before using.
Further, in step (3), steam being placed on after bolus on Folium Nelumbinis.
Further, in step (3), bolus after steaming pulverizes, sieve after dry again.
The application in terms of gastrotherapy of the above-mentioned lamb liver powder.
In the present invention, Hepar Caprae seu ovis, cool in nature, sweet-bitter flavor;Nourishing the liver, improving eyesight, enrich blood, clearind deficient heat.
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature;Return spleen, stomach warp;Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For spleen Empty lack of appetite, abdominal distention has loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Semen Lablab Album has antibacterial, antivirus action, to dysentery bacterium and have inhibitory action;Cause alimentary toxicosis vomits Tell, acute gastroenteritis etc. has Detoxication.
Fructus Amomi, warm in nature, acrid in the mouth, there is warming the spleen and kidney, therapeutic method to keep the adverse QI flowing downwards pain relieving, the chest stuffiness relieving diaphragm, dredge the stagnation of QI, except vomiting, increasing food Be intended to, only cold diarrhea, whet the appetite, change effect stagnant, that help digestion, can effectively treat stomachache distension, increased borborygmus and diarrhea, indigestion, vomiting Clear water, thick fur are greasy.
Cortex Magnoliae Officinalis, bitter in the mouth, pungent;Warm in nature;Return spleen channel, stomach warp, large intestine channel;There is circulation of qi promoting removing food stagnancy, dampness except full, sending down the abnormal ascending QI The function relievingd asthma.Cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, expectorant stops up QI rising in reverse order, fullness in the chest is breathed with cough.
Aloe, bitter in the mouth, cold in nature, have under sterilization, antiinflammatory, stomach invigorating and let out effect, it is possible to heart tonifying is invigorated blood circulation.
Poria, sweet in the mouth, light, property is put down;GUIXIN, lung, spleen, kidney channel;Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming;For edema Oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Cera Flava, another name Apis cerana Fabricius, wax, the honey sole of the foot, Cera Flava, white beeswax, Huang account for;Sweet in the mouth, slightly warm in nature;Return spleen channel;There is solution Poison, sore, granulation promoting, effect of pain relieving.
Fructus Crataegi, sour in the mouth is sweet, slightly warm in nature;Enter spleen, stomach, Liver Channel;Help digestion long-pending, dissipating blood stasis blood, expelling tenia.Control meat to amass, disease Abdominal mass, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia after-pains in puerperal, lochiorrhea, children's's breast food is stagnated. Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's thorn Bitterly, hernia pain, hyperlipidemia.
Folium Nelumbinis has a summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, effect of dissipating blood stasis hemostasis, is placed on bolus on Folium Nelumbinis to steam and is conducive to carrying The opsonic action to stomach of high lamb liver powder.
The lamb liver powder that the present invention provides is to superficial gastritis, and erosive gastritis, gastroptosis, caused by the gastropathy such as gastric ulcer The disease effects such as stomachache, turns sour, have the hiccups, heartburn, abdominal distention, diarrhoea, suffers from diarrhea throughout the year, complexion fulminant jaundice, anorexia are notable.
The lamb liver powder prepared by the present invention is easily absorbed, and on the premise of ensureing drug effect, improves flavour of a drug, decreases trouble Person takes pharmacophagous misery.Patent Appetitive stomachic of the present invention, dehumidify spleen invigorating, increases gastrointestinal function.This patent is taken from natural Chinese patent medicine preparation, has the dual function for the treatment of and conditioning;Original prescription can attack focus directly, drives away pathogenic QI in the body;The natural one-tenth of Chinese medicine Divide containing abundant nutrient substance, therefore can repair the gastric ulcer of breakage, elimination gastropathy recurrent exerbation root, thus relapse rate Low, curative effect is lasting.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in detail.
Embodiment 1
A kind of lamb liver powder, dosage form is powder, is mainly prepared from by the crude drug of following weight kilogram: Hepar Caprae seu ovis 2 kilograms, the Rhizoma Atractylodis Macrocephalae 1 are public Jin, Semen Lablab Album 1 kilogram, Fructus Amomi 3 kilograms, Cortex Magnoliae Officinalis 1 kilogram, Aloe 5 kilograms, Poria 1 kilogram, 3 kilograms of Cera Flava, mountain Short, bristly hair or beard 1 kilogram, Folium Nelumbinis 1 (weight is 0.08~0.12 kilogram).
Above-mentioned lamb liver powder uses following methods to prepare:
(1) Hepar Caprae seu ovis section is dried;Aloe intense fire heating, drying is reduced to original 1/3rd to weight;
(2) Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Crataegi are fried to micro-Huang, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Amomi, Cortex Magnoliae Officinalis, Poria, Fructus Crataegi, Hepar Caprae seu ovis are mixed Close, pulverize to obtain medicated powder;
(3) medicated powder of step (2) gained extremely can be pinched balling-up with Aloe powder mixing, the stirring that adds water, Folium Nelumbinis be divided on food steamer, Then it is placed on Folium Nelumbinis after medicated powder and Aloe powder being made bolus and steams 2 hours, pulverize, sieve, dry;
(4) step (3) gained medicine is mixed 20 minutes with the Cera Flava stirring after heating and melting, obtain lamb liver powder.
The application in terms of gastrotherapy of the above-mentioned lamb liver powder.
Embodiment 2
A kind of lamb liver powder, dosage form is powder, is mainly prepared from by the crude drug of following weight kilogram: Hepar Caprae seu ovis 1 kilogram, the Rhizoma Atractylodis Macrocephalae 2 are public Jin, Semen Lablab Album 2 kilograms, Fructus Amomi 5 kilograms, Cortex Magnoliae Officinalis 2 kilograms, Aloe 8 kilograms, Poria 1 kilogram, 1 kilogram of Cera Flava, mountain Short, bristly hair or beard 2 kilograms, Folium Nelumbinis 1 (weight is 0.08~0.12 kilogram).
The preparation method of above-mentioned lamb liver powder, comprises the following steps:
(1) Hepar Caprae seu ovis section is dried;Aloe intense fire heating, drying is reduced to original 1/3rd to weight;
(2) Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Crataegi are fried to micro-Huang, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Amomi, Cortex Magnoliae Officinalis, Poria, Fructus Crataegi, Hepar Caprae seu ovis are mixed Close, pulverize to obtain medicated powder;
(3) medicated powder of step (2) gained extremely can be pinched balling-up with Aloe powder mixing, the stirring that adds water, Folium Nelumbinis be divided on food steamer, Then it is placed on Folium Nelumbinis after medicated powder and Aloe powder being made bolus and steams 1 hour, pulverize, sieve, dry;
(4) step (3) gained medicine is mixed 20 minutes with the Cera Flava stirring after heating and melting, obtain lamb liver powder.
The application in terms of gastrotherapy of the above-mentioned lamb liver powder.
Embodiment 3
A kind of lamb liver powder, dosage form is powder, is mainly prepared from by the crude drug of following weight kilogram: Hepar Caprae seu ovis 2 kilograms, the Rhizoma Atractylodis Macrocephalae 1.5 Kilogram, Semen Lablab Album 2 kilograms, Fructus Amomi 3 kilograms, Cortex Magnoliae Officinalis 1 kilogram, Aloe 8 kilograms, Poria 2 kilograms, 3 kilograms of Cera Flava, Fructus Crataegi 1 kilogram, Folium Nelumbinis 1 (weight is 0.08~0.12 kilogram).
Its preparation method is same as in Example 1.
The application in terms of gastrotherapy of the above-mentioned lamb liver powder.
Embodiment 4 clinical trial
Case 1
Wang, man, 47 years old, people from Henan.Gastroscopy: erosive gastritis, is specially stomachache, complexion fulminant jaundice, inappetence.
Take the lamb liver powder of embodiment 1 preparation, once a day, one time 21 grams, gastroscopy after medication 21 days: Recover normal.
Case 2
Wang is firm, man, 25 years old.Clinical examination is superficial gastritis, specially has the hiccups, inappetence, diarrhoea.
Take embodiment 1 preparation lamb liver powder, once a day, one time 21 grams, medication have the hiccups after 24 days phenomenon disappear, Appetite is recovered, transference cure of suffering from diarrhea.
Case 3
Zhang is beautiful, female, 36 years old.Clinical examination is superficial gastritis, shows as stomachache, inappetence.
Take the lamb liver powder of embodiment 1 preparation, once a day, one time 21 grams, after medication 18 days, stomachache disappears, drink Food recovers normal.
Case 4
History is, man, 14 years old.Clinical examination is superficial gastritis, shows as emaciation and sallow complexion, stomachache, inappetence.
Take the lamb liver powder of embodiment 1 preparation, once a day, one time 21 grams, after medication 30 days, stomachache disappears, drink Food recovers normal.
Case 5
Zhu is strong, man, 43 years old.Clinical examination is erosive gastritis, show as stomachache, inappetence, diarrhoea, acid regurgitation water, Heartburn.
Take the lamb liver powder of embodiment 1 preparation, once a day, one time 21 grams, symptom of suffering from diarrhea after medication 60 days disappears Losing, appetite is recovered, and stomachache disappears.

Claims (9)

1. a lamb liver powder, it is characterised in that be mainly prepared from by the crude drug of following weight parts: Hepar Caprae seu ovis 1~2 parts, the Rhizoma Atractylodis Macrocephalae 1~2 Part, Semen Lablab Album 1~2 parts, Fructus Amomi 3~5 parts, Cortex Magnoliae Officinalis 1~2 parts, Aloe 5~8 parts, Poria 1~2 parts, Cera Flava 1~3 parts, Fructus Crataegi 1~2 parts.
Lamb liver powder the most according to claim 1, it is characterised in that be mainly prepared from by the crude drug of following weight parts: sheep Liver 2 parts, the Rhizoma Atractylodis Macrocephalae 1 part, Semen Lablab Album 1 part, Fructus Amomi 3 parts, Cortex Magnoliae Officinalis 1 part, Aloe 5 parts, Poria 1 part, 3 parts of Cera Flava, Fructus Crataegi 1 part.
Lamb liver powder the most according to claim 1 and 2, it is characterised in that its dosage form is powder.
4. the preparation method of the lamb liver powder described in claim 1 or 2, it is characterised in that comprise the following steps:
(1) Hepar Caprae seu ovis section is dried;
(2) by the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Amomi, Cortex Magnoliae Officinalis, Poria, Fructus Crataegi, Hepar Caprae seu ovis mixing, medicated powder is pulverized to obtain;
(3) by the medicated powder of step (2) gained with Aloe powder mixing, add water stirring, after then medicated powder and Aloe powder being made bolus, 1-is steamed 2 hours, dry;
(4) step (3) gained medicine is mixed homogeneously with the Cera Flava after heating and melting i.e. obtain lamb liver powder.
The preparation method of lamb liver powder the most according to claim 4, it is characterised in that fresh aloe intense fire heating, drying is to weight After being reduced to original 1/3rd, then mix with the medicated powder of step (2) gained.
The preparation method of lamb liver powder the most according to claim 4, it is characterised in that in step (2), the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Fructus Crataegi first carries out parch before using.
7. the preparation method of the lamb liver powder described in claim 4, it is characterised in that in step (3), by be placed on after bolus Folium Nelumbinis it On steam.
8. the preparation method of the lamb liver powder described in claim 7, it is characterised in that the bolus powder in step (3), after steaming Broken, sieve after dry again.
9. the application in terms of gastrotherapy of the lamb liver powder described in claim 1 or 2.
CN201610394862.6A 2016-06-07 2016-06-07 Sheep liver powder and preparation method and application thereof Pending CN105999027A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915350A (en) * 2005-08-17 2007-02-21 郝素梅 Composition of medication for treating gastric disease
CN104707069A (en) * 2013-12-12 2015-06-17 陕西康乐中医药养生研究院 Traditional Chinese medicine for treating gastric ulcer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915350A (en) * 2005-08-17 2007-02-21 郝素梅 Composition of medication for treating gastric disease
CN104707069A (en) * 2013-12-12 2015-06-17 陕西康乐中医药养生研究院 Traditional Chinese medicine for treating gastric ulcer

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