CN105998824A - 一种治疗疫毒炽盛型病毒性肝炎的中药及其制备方法 - Google Patents

一种治疗疫毒炽盛型病毒性肝炎的中药及其制备方法 Download PDF

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CN105998824A
CN105998824A CN201610520233.3A CN201610520233A CN105998824A CN 105998824 A CN105998824 A CN 105998824A CN 201610520233 A CN201610520233 A CN 201610520233A CN 105998824 A CN105998824 A CN 105998824A
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黄科钧
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Abstract

本发明提供一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈15‑22份、水牛角15‑22份、生大黄8‑12份、栀子10‑15份、黄连5‑9份、黄芩10‑15份、生地10‑15份、玄参10‑15份、丹皮10‑15份、赤芍10‑15份、金银花8‑12份、白花蛇舌草12‑18份、半边莲10‑15份、连翘8‑12份、丹参12‑18份、白茅根15‑22份、紫草10‑15份、生甘草5‑9份。本发明还提供该中药的制备方法。本发明的目的是按照“清营凉血，解毒利湿”的治疗原则，提供的该中药不仅治愈速度快，愈后不易复发，而且无任何毒副作用，对身体健康还有良好的调理作用。

Description

一种治疗疫毒炽盛型病毒性肝炎的中药及其制备方法
技术领域
本发明属于一种中药，具体涉及一种治疗疫毒炽盛型病毒性肝炎的中药及其制备方法。
背景技术
病毒性肝炎是由多种肝炎病毒引起的以肝脏病变为主的一种传染病。临床上以食欲减退、恶心、上腹部不适、肝区痛、乏力为主要表现。部分病人可有黄疸发热和肝大伴有肝功能损害。有些病人可慢性化，甚至发展成肝硬化，少数可发展为肝癌。对病毒性肝炎要尽早诊断、隔离、报告、治疗及处理，以防止流行。
本病病位在肝，与肝、胆、脾。胃、肾等脏腑有关。外因为感受疫毒湿热之邪，内因为正气虚弱。急性肝炎以实证为主，主要是感受湿热邪毒，郁结脾胃，熏蒸肝胆，阻滞气机所致。慢性肝炎多虚实夹杂，主要是外邪留恋，肝脾不和，肝肾亏虚，脉络瘀阻所致。瘀胆型也是虚实夹杂，主要是湿热留恋，熏蒸肝胆，脾虚血瘀所致。重症肝炎病候危重，主要是疫毒炽盛，化火化燥，内陷营血，邪热内闭，元气欲脱所致。
病毒性肝炎是由多种不同肝炎病毒引起的一组以肝脏害为主的传染病，根据病原学诊断，肝炎病毒至少有5 种，即甲、乙、丙、丁、戊型肝炎病毒，分别引起甲、乙、丙、丁、戊型病毒性肝炎，即甲型肝炎、乙型肝炎、丙型肝炎、丁型肝炎及戊型肝炎；另外一种称为庚型病毒性肝炎，较少见，病毒性肝炎主要通过粪- 口、血液或体液传播；临床上以疲乏、食欲减退、肝肿大、肝功能异常为主要表现，部分病例出现黄疸，无症状感染常见，目前，对于肝病治疗，均有一些治疗性中药，但是，现有技术的中药在治疗的特异性和药物的多样性方面还远远不能满足病毒性肝炎患者的需求，并且现在用中药在治疗病毒性肝炎的方法中，大多数没有很好的区分出不同类型临床表现的不同，所用的药品也不同，没有很好的运用中医在辨证论治中的对症治疗好处。
疫毒炽盛型病毒性肝炎的症状：发病急骤，黄疽迅速加深，鲜明如金色，高热烦渴，胁肋胀痛，纳少呕吐，嗜睡，神昏谵语，极度疲乏，或兼见衄血或便血，小便深黄。舌红绛，苔黄燥，脉弦滑数或细数。多见于重症肝炎。
发明内容
本发明的目的是按照“清营凉血，解毒利湿”治疗原则，提供一种治疗疫毒炽盛型病毒性肝炎的中药及其制备方法，采用该中药不仅治愈速度快，愈后不易复发，而且无任何毒副作用，对身体健康还有良好的调理作用。
本发明的目的是这样实现的，一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈15-22份、水牛角15-22份、生大黄8-12份、栀子10-15份、黄连5-9份、黄芩10-15份、生地10-15份、玄参10-15份、丹皮10-15份、赤芍10-15份、金银花8-12份、白花蛇舌草12-18份、半边莲10-15份、连翘8-12份、丹参12-18份、白茅根15-22份、紫草10-15份、生甘草5-9份。
优选的， 所述一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈18份、水牛角18份、生大黄9份、栀子12份、黄连6份、黄芩12份、生地12份、玄参12份、丹皮12份、赤芍12份、金银花10份、白花蛇舌草15份、半边莲12份、连翘9份、丹参15份、白茅根18份、紫草12份、生甘草6份。
所述的一种治疗疫毒炽盛型病毒性肝炎的中药的制备方法为，取各原料药，混合，加5 ～ 8倍量水，浸泡45～60分钟，然后常规煎煮2 ～ 3 小时，过滤得滤液，向滤渣中加5～ 8 倍量水，常规煎煮2 ～ 3 小时，过滤得滤液，合并两次滤液，浓缩至相对密度为1.30～ 1.50 的浓缩液，加入与浓缩液2倍体积量的乙醇，混匀后，回收乙醇至无乙醇味，喷雾干燥，得治疗疫毒炽盛型病毒性肝炎的中药的口服制剂，或：加入常规的药用辅料制成颗粒剂或片剂或冲剂。
本发明中药的药理作用如下：
茵陈：苦、辛，微寒。归脾、胃、肝、胆经。清湿热，退黄疸。用于黄疸尿少，湿疮瘙痒；传染性黄疸型肝炎。主治：黄疸、小便不利、湿疮瘙痒、传染性黄疸型肝炎等药理学研究有利胆，保护肝功能解热，抗炎，降血脂，扩冠等作用，茵陈有显著的保肝作用，对甲,乙型肝炎,黄疸型肝炎，有显著的疗效。有利胆,促进胆汁分泌，增加胆汁中胆酸和胆红素排出的作用.能增加心脏冠脉血流量,改善微循环，并有降血压,降血脂，抗凝血,利尿解热平喘，驱除蛔虫及抑制多种致病性皮肤真菌与细菌的作用。
水牛角：味苦；咸；性寒。归心经；肝经。清热；解毒；凉血；定惊。主热病头痛；商热神昏；发斑发疹；吐血、衄血；瘀热发黄；小儿惊风及咽喉肿痛；口舌生疮。
生大黄：药性 苦；性寒 。归经 胃；大肠；肝；脾经 。功效：泻下攻积，清热泻火，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，外治水火烫伤。酒大黄善清上焦血分热毒，用于目赤咽肿，齿龈肿痛。熟大黄泻下力缓，泻火解毒，用于火毒疮疡。大黄炭凉血化瘀止血，用于血热有瘀出血者。
栀子：苦，寒。入心、肝、肺、胃经。清热，泻火，凉血。治热病虚烦不眠，黄疸，淋病，消渴，目赤，咽痛，吐血，衄血，血痢，尿血，热毒疮疡，扭伤肿痛。
黄连：苦，寒。归心、脾、胃、肝、胆、大肠经。功能主治：清热燥湿，泻火解毒。用于湿热痞满，呕吐吞酸，泻痢，黄疸，高热神昏，心火亢盛，心烦不寐，血热吐衄，目赤，牙痛，消渴，痈肿疔疮；外治湿疹，湿疮，耳道流脓。酒黄连善清上焦火热。用于目赤，口疮。姜黄连清胃和胃止呕。用于寒热互结，湿热中阻，痞满呕吐。萸黄连舒肝和胃止呕。用于肝胃不和，呕吐吞酸。
黄芩：味苦，性寒。归肺、胆、脾、大肠、小肠经。功能主治：清热燥湿，泻火解毒，止血，安胎，降血压。用于湿温、暑温胸闷呕恶，湿热痞满，泻痢，黄疸，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒，胎动不安。
生地：性味：甘苦，凉。归经：入心、肝、肾经。清热凉血，养阴，生津。用于热病舌绛烦渴，阴虚内热，骨蒸劳热，内热消渴，吐血，衄血，发斑发疹。
玄参：味甘、苦、咸； 性微寒。归肺，胃，肾经。：清热凉血，泻火解毒，滋阴。【主治】：温邪入营，内陷心包，温毒发斑，热病伤阴、舌绛烦渴、津伤便秘、骨蒸劳嗽、目赤、咽痛、瘰疬、白喉、痈肿疮毒。
丹皮：苦、辛，微寒。归心经、肝经、肾经。清热凉血，和血消瘀。治热入血分，发斑，惊痫，吐、衄、便血，骨蒸劳热，经闭，癥瘕，痈疡，跌打损伤。
赤芍：味苦，性微寒。归肝经。清热凉血，散瘀止痛。用于温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，症瘕腹痛，跌扑损伤，痈肿疮疡。
金银花：性寒，味甘，入肺、心、胃经，具有清热解毒、抗炎、补虚疗风的 功效，主治胀满下疾、温病发热，热毒痈疡和肿瘤等症。其对于头昏头晕、口干作渴、多汗烦闷、肠炎、菌痢、 麻疹、 肺炎、 乙脑、 流脑、急性乳腺炎、 败血症、 阑尾炎、皮肤感染、痈疽疔疮、丹毒、腮腺炎、化脓性扁桃体炎等病症均有一定疗效。
白花蛇舌草：苦甘，寒。入心、肝、脾三经。清热，利湿，解毒。治肺热喘咳，扁桃体炎。咽喉炎，阑尾炎，痢疾，尿路感染，黄疸，肝炎，盆腔炎，附件炎，痈肿疔疮，毒蛇咬伤，肿瘤。亦可用于消化道癌症。
半边莲：清热解毒；利尿消肿。用于痈肿疔疮，蛇虫蛟伤，膨胀水肿，湿热黄疸，湿疹湿疮。
连翘：【性味】苦，凉。【归经】入心、肝、胆经。清热解毒，消肿散结。用于痈疽，瘰疠，乳痈，丹毒，风热感冒，温病初起，温热入营，高热烦渴，神昏发斑，热淋尿闭。
丹参：性味：味苦，微寒。归经：归心、肝经。祛瘀止痛，活血通经，清心除烦。用于月经不调，经闭痛经，症瘕积聚，胸腹刺痛，热痹疼痛，疮疡肿痛，心烦不眠；肝脾肿大，心绞痛。
白茅根：味甘苦，性寒，无毒。入肺经、胃经、小肠经。凉血止血，清热解毒，主治吐血、尿血、热淋、水肿、黄疸等，脾胃虚寒者忌服。
紫草：苦；寒。入心包络、肝经。凉血，活血，解毒透疹。用于血热毒盛，斑疹紫黑，麻疹不透，疮疡，湿疹，水火烫伤。
甘草：【性味】：甘，平。【归经】：入脾、胃、肺经。益气补中；缓急止痛；润肺止咳；泻火解毒；调和诸药。主倦怠食少；肌瘦面黄；心悸气短；腹痛便溏；四肢挛急疼痛；脏躁；咳嗽气喘；咽喉肿痛；痈疮肿痛；小儿胎毒；及药物、食物中毒。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
本发明的中药，具有清营凉血，解毒利湿，保肝祛毒等功效，适应于治疗疫毒炽盛型病毒性肝炎，经临床验证，其具有见效快、疗效确切、有效率高、远期效果好等优点。
具体实施方式
下面结合实施例对本发明作进一步的说明，下述该实施例仅用于说明本发明而对本发明没有限制。
实施例1
一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈18份、水牛角18份、生大黄9份、栀子12份、黄连6份、黄芩12份、生地12份、玄参12份、丹皮12份、赤芍12份、金银花10份、白花蛇舌草15份、半边莲12份、连翘9份、丹参15份、白茅根18份、紫草12份、生甘草6份。
制备方法为，取各原料药，混合，加6倍量水，浸泡55分钟，然后常规煎煮2.5小时，过滤得滤液，向滤渣中加6倍量水，常规煎煮2.5小时，过滤得滤液，合并两次滤液，浓缩至相对密度为1.45的浓缩液，加入与浓缩液2倍体积量的乙醇，混匀后，回收乙醇至无乙醇味，喷雾干燥，得治疗疫毒炽盛型病毒性肝炎的中药的口服制剂。
实施例2
一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈15份、水牛角15份、生大黄8份、栀子10份、黄连5份、黄芩10份、生地10份、玄参10份、丹皮10份、赤芍10份、金银花8份、白花蛇舌草12份、半边莲10份、连翘8份、丹参12份、白茅根15份、紫草10份、生甘草5份。
制备方法为，取各原料药，混合，加5倍量水，浸泡45分钟，然后常规煎煮2 小时，过滤得滤液，向滤渣中加5 倍量水，常规煎煮2 小时，过滤得滤液，合并两次滤液，浓缩至相对密度为1.30 的浓缩液，加入与浓缩液2倍体积量的乙醇，混匀后，回收乙醇至无乙醇味，喷雾干燥，得治疗疫毒炽盛型病毒性肝炎的中药的口服制剂，加入常规的药用辅料制成颗粒剂。
实施例3
一种治疗疫毒炽盛型病毒性肝炎的中药，其由以下原料药组成：茵陈22份、水牛角22份、生大黄12份、栀子15份、黄连9份、黄芩15份、生地15份、玄参15份、丹皮15份、赤芍15份、金银花12份、白花蛇舌草18份、半边莲15份、连翘12份、丹参18份、白茅根22份、紫草15份、生甘草9份。
制备方法为，取各原料药，混合，加8倍量水，浸泡60分钟，然后常规煎煮 3 小时，过滤得滤液，向滤渣中加8 倍量水，常规煎煮3 小时，过滤得滤液，合并两次滤液，浓缩至相对密度为1.50 的浓缩液，加入与浓缩液2倍体积量的乙醇，混匀后，回收乙醇至无乙醇味，喷雾干燥，得治疗疫毒炽盛型病毒性肝炎的中药的口服制剂，加入常规的药用辅料制成片剂。

Claims (3)

1.一种治疗疫毒炽盛型病毒性肝炎的中药，其特征在于：其由以下原料药组成：茵陈15-22份、水牛角15-22份、生大黄8-12份、栀子10-15份、黄连5-9份、黄芩10-15份、生地10-15份、玄参10-15份、丹皮10-15份、赤芍10-15份、金银花8-12份、白花蛇舌草12-18份、半边莲10-15份、连翘8-12份、丹参12-18份、白茅根15-22份、紫草10-15份、生甘草5-9份。
2.根据权利要求1 所述一种治疗疫毒炽盛型病毒性肝炎的中药，其特征在于：其由以下原料药组成：茵陈18份、水牛角18份、生大黄9份、栀子12份、黄连6份、黄芩12份、生地12份、玄参12份、丹皮12份、赤芍12份、金银花10份、白花蛇舌草15份、半边莲12份、连翘9份、丹参15份、白茅根18份、紫草12份、生甘草6份。
3.权利要求1 和2 所述的一种治疗疫毒炽盛型病毒性肝炎的中药的制备方法，其特征在于：取各原料药，混合，加5 ～ 8倍量水，浸泡45～60分钟，然后常规煎煮2 ～ 3 小时，过滤得滤液，向滤渣中加5 ～ 8 倍量水，常规煎煮2 ～ 3 小时，过滤得滤液，合并两次滤液，浓缩至相对密度为1.30 ～ 1.50 的浓缩液，加入与浓缩液2倍体积量的乙醇，混匀后，回收乙醇至无乙醇味，喷雾干燥，得治疗疫毒炽盛型病毒性肝炎的中药的口服制剂，或：加入常规的药用辅料制成颗粒剂或片剂或冲剂。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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* Cited by examiner, † Cited by third party
Title
学中医书馆: "消化系统中医辨证论治大全", 《360DOC.COM个人图书馆》 *

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