CN105998573A - Externally applied medicament for repairing scars and preparation method thereof - Google Patents
Externally applied medicament for repairing scars and preparation method thereof Download PDFInfo
- Publication number
- CN105998573A CN105998573A CN201610526860.8A CN201610526860A CN105998573A CN 105998573 A CN105998573 A CN 105998573A CN 201610526860 A CN201610526860 A CN 201610526860A CN 105998573 A CN105998573 A CN 105998573A
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- extract
- cicatrix
- allantoin
- carbomer
- butanediol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
The invention provides an externally applied medicament for repairing scars. The externally applied medicament is prepared from, by weight, 50%-65% of water, 5%-8% of glycerin, 3%-4% of xanthan gum, 4%-6% of butanediol, 2%-3% of carbomer, 0.2%-0.5% of sodium hyaluronate, 0.3%-1.2% of sodium hydroxide, 0.5%-0.9% of allantoin, 0.3%-0.5% of nicotinamide, 1%-3% of glycosaminoglycans, 2%-4% of ethylhexylglycerin, 1.5%-1.8% of kava pepper extract, 3%-6% of onion extract, 0.1%-0.6% of amaranthus caudatus seed extract, 1.5%-1.6% of hydrogenated lecithin, 1.2%-1.6% of sorbitol, 1.6%-2.3% of 1,2-hexanediol, 2%-5% of tocopheryl acetate, 3%-4% of soluble collagen, 3.5%-6.5% of herba portulacae extract and 5%-10% of aloe barbadensis leaf juice. The invention further provides a preparation method of the externally applied medicament for repairing the scars.
Description
Technical field
The present invention is a kind of external preparation repairing cicatrix and preparation method thereof, belongs to medicines and health protection nursing technique field.
Background technology
" cicatrix " is that the detrimental effect of the factors such as physics, biology, chemistry is in human body skin soft tissue, causing the major injury of skin soft tissue the most normally not repair, turning the outward appearance that i.e. affects stayed by fibrous tissue replacement reparation affects again the local symptom of function.What " cicatrix " brought to patient is that the huge human body is painful and psychic pain, the cicatrix especially burnt, scald, leave over after severe trauma.
The people of cicatrix body constitution ratio in crowd is minimum, and after it shows as wound healing, surface scars is that persistence increases, and not only affects outward appearance, and local pain, red itches, and cicatrix shrinks and has an effect on functional movement.Just because of the people of cicatrix body constitution is relatively fewer, because the current inspection method of keloid is few, therefore the people of long keloid is also referred to as cicatrix body constitution, cicatrix body constitution and keloid are distinguishing, after the most of site tissue damage of its health of cicatrix body constitution person, can occur such as keloid sample scar healing.In other words, keloid is that the one of cicatrix body constitution necessarily shows, and the keloidal crowd not necessarily belonging to cicatrix body constitution occurs.Cicatrix body constitution shows as spontaneously forming, and predilection site mostly is shirtfront, omoplate, and surface scars is that persistence increases, and color is red, matter is hard, fading of pressure, convex in normal skin surface, and women sends out well rate more than male.Not only affecting outward appearance but also local time has sufferings sense, hypertrophic cicatrix and keloid body constitution to be distinguishing, it is convex in normal skin that hypertrophic cicatrix shows as wound surface healing, matter is hard, and color is red, time have sufferings sense, especially with edible pungent stimulation food, it is particularly acute after drinking.But grow into a certain degree with crossed proliferation period, if do not stimulated skin area, continue extension probability less, its health predilection site of cicatrix body constitution or any cause breakage reason all can cause unlimited hypertrophy.
Cicatrix is a concept the most general, and it is mode of appearance and the general designation of histopathologic change of normal skin tissue caused after various wound.After it is human body wound, a kind of normal, the inevitable physiological reaction during wound or wound surface normal healing, is also the inevitable outcome of wound healing process.The essence of cicatrix is a kind of not possess normal skin tissue's structure and physiological function, loses normal structure vigor, abnormal, unsound tissue.It is beautiful that cicatrix has not only broken up body surface, also can interfere with the physiological function of linked groups or organ, even results in deformity.
Summary of the invention
The deficiency existed for prior art, it is an object of the present invention to provide a kind of external preparation repairing cicatrix and preparation method thereof, and to solve the problem proposed in above-mentioned background technology, the present invention is easy to use, it is simple to operation, good stability, and reliability is high.
nullTo achieve these goals，The present invention is to realize by the following technical solutions: a kind of external preparation repairing cicatrix，It is made up by weight percentage of following component: water 50-65%、Glycerol 5-8%、Xanthan gum 3-4%、Butanediol 4-6%、Carbomer 2-3%、Hyaluronate sodium 0.2-0.5%、Sodium hydroxide 0.3-1.2%、Allantoin 0.5-0.9%、Nicotiamide 0.3-0.5%、Glucose glycosaminoglycan 1-3%、Sensiva SC50 2-4%、Piper methysticum extract 1.5-1.8%、Bulbus Allii Cepae extract 3-6%、Amaranthus caudatus seed extract 0.1-0.6%、Hydrolecithin 1.5-1.6%、Sorbitol 1.2-1.6%、1,2-hexanediol 1.6-2.3%、Tocopherol acetas 2-5%、Soluble collagen 3-4%、Herba portulacae extract 3.5-6.5%、Aloe Barbadensis Miller juice 5-10%.
Further, described piper methysticum extract is a kind of piper methysticum leaf/root/stem extract.
Further, described Bulbus Allii Cepae extract is a kind of onion bulb stem extract.
Further, it is made up by weight percentage of following component: water 55%, glycerol 5%, xanthan gum 3%, butanediol 4%, carbomer 2%, hyaluronate sodium 0.2%, sodium hydroxide 0.3%, allantoin 0.5%, nicotiamide 0.3%, glucose glycosaminoglycan 1.7%, Sensiva SC50 2%, piper methysticum extract 1.5%, Bulbus Allii Cepae extract 3%, amaranthus caudatus seed extract 0.5%, hydrolecithin 1.5%, sorbitol 1.4%, 1,2-hexanediol 1.6%, tocopherol acetas 2%, soluble collagen 3.5%, Herba portulacae extract 3.5%, Aloe Barbadensis Miller juice 7.5%.
A kind of preparation method of the external preparation repairing cicatrix, take glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide, by glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide deionized water, piper methysticum extract, Bulbus Allii Cepae extract, amaranthus caudatus seed extract, hydrolecithin, sorbitol, 1, 2-hexanediol, tocopherol acetas, soluble collagen, 75～85 DEG C it are warming up to after Herba portulacae extract stirring and evenly mixing, take out after insulation 10～15min, stirring cools to about 40 DEG C, sequentially add Aloe Barbadensis Miller juice and water, i.e. complete after stirring and dissolving is complete.
Beneficial effects of the present invention: a kind of external preparation repairing cicatrix of the present invention and preparation method thereof, in the present invention, composition has the effect of bactericidal antiphlogistic, can skin expansion blood capillary, promote skin microcirculation, repair cell strengthening cell viability, accelerate metabolism, recover the function of collagen protein, make impaired skin obtain deep layer reparation；According to clinical verification, it is safe and effective that the present invention nurses ointment, the cicatrix caused for scald, scratch, knife injury, operation wound, comedo, acne etc. is respectively provided with good effect, product contains various plants extract, deep layer can moisten moisturizing, the impaired skin of maintenance, increase skin shine and elasticity, represent the smooth moist sense of skin, distribute charming brilliance.
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, below in conjunction with detailed description of the invention, the present invention is expanded on further.
nullThe present invention provides a kind of technical scheme: a kind of external preparation repairing cicatrix，It is made up by weight percentage of following component: water 50-65%、Glycerol 5-8%、Xanthan gum 3-4%、Butanediol 4-6%、Carbomer 2-3%、Hyaluronate sodium 0.2-0.5%、Sodium hydroxide 0.3-1.2%、Allantoin 0.5-0.9%、Nicotiamide 0.3-0.5%、Glucose glycosaminoglycan 1-3%、Sensiva SC50 2-4%、Piper methysticum extract 1.5-1.8%、Bulbus Allii Cepae extract 3-6%、Amaranthus caudatus seed extract 0.1-0.6%、Hydrolecithin 1.5-1.6%、Sorbitol 1.2-1.6%、1,2-hexanediol 1.6-2.3%、Tocopherol acetas 2-5%、Soluble collagen 3-4%、Herba portulacae extract 3.5-6.5%、Aloe Barbadensis Miller juice 5-10%.
Piper methysticum extract is a kind of piper methysticum leaf/root/stem extract, and Bulbus Allii Cepae extract is a kind of onion bulb stem extract.
A kind of preparation method of the external preparation repairing cicatrix, take glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide, by glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide deionized water, piper methysticum extract, Bulbus Allii Cepae extract, amaranthus caudatus seed extract, hydrolecithin, sorbitol, 1, 2-hexanediol, tocopherol acetas, soluble collagen, 75～85 DEG C it are warming up to after Herba portulacae extract stirring and evenly mixing, take out after insulation 10～15min, stirring cools to about 40 DEG C, sequentially add Aloe Barbadensis Miller juice and water, i.e. complete after stirring and dissolving is complete.
As one embodiment of the present of invention: be made up by weight percentage of following component: water 55%, glycerol 5%, xanthan gum 3%, butanediol 4%, carbomer 2%, hyaluronate sodium 0.2%, sodium hydroxide 0.3%, allantoin 0.5%, nicotiamide 0.3%, glucose glycosaminoglycan 1.7%, Sensiva SC50 2%, piper methysticum extract 1.5%, Bulbus Allii Cepae extract 3%, amaranthus caudatus seed extract 0.5%, hydrolecithin 1.5%, sorbitol 1.4%, 1, 2-hexanediol 1.6%, tocopherol acetas 2%, soluble collagen 3.5%, Herba portulacae extract 3.5%, Aloe Barbadensis Miller juice 7.5%.
Glycerol is taken by above-mentioned formula, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide, by glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide deionized water, piper methysticum extract, Bulbus Allii Cepae extract, amaranthus caudatus seed extract, hydrolecithin, sorbitol, 1, 2-hexanediol, tocopherol acetas, soluble collagen, 75～85 DEG C it are warming up to after Herba portulacae extract stirring and evenly mixing, take out after insulation 10～15min, stirring cools to about 40 DEG C, sequentially add Aloe Barbadensis Miller juice and water, i.e. complete after stirring and dissolving is complete.
In the present invention, composition has the effect of bactericidal antiphlogistic, it is possible to skin expansion blood capillary, promotes skin microcirculation, repair cell strengthening cell viability, accelerates metabolism, recover the function of collagen protein, make impaired skin obtain deep layer reparation；According to clinical verification, it is safe and effective that the present invention nurses ointment, the cicatrix caused for scald, scratch, knife injury, operation wound, comedo, acne etc. is respectively provided with good effect, product contains various plants extract, deep layer can moisten moisturizing, the impaired skin of maintenance, increase skin shine and elasticity, represent the smooth moist sense of skin, distribute charming brilliance.
Usage and dosage: at clear water cleaning cicatrix, dry, by the external preparation uniform application of the present invention in affected part, with referring to that abdomen is massaged into after ointment fully absorbs gently,；Once, medication one month is visible positive effect, within three to five months, can repair cicatrix in medication in every six hours；Cicatrix adopts 15 days after disappearing；The cicatrix caused for scalding, abrade knife injury, surgical wound, comedo, acne etc. all has good effect.
Condition of storage: deposit in shady and cool being dried and locate.
The ultimate principle of the present invention and principal character and advantages of the present invention have more than been shown and described, to those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing from the spirit or essential characteristics of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter from the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is limited by claims rather than described above, it is intended that all changes fallen in the implication of equivalency and scope of claim included in the present invention.Should not be considered as limiting involved claim by any labelling in claim.
In addition, it is to be understood that, although this specification is been described by according to embodiment, but the most each embodiment only comprises an independent technical scheme, this narrating mode of description is only for clarity sake, description should can also be formed, through appropriately combined, other embodiments that it will be appreciated by those skilled in the art that as an entirety, the technical scheme in each embodiment by those skilled in the art.
Claims (5)
- null1. the external preparation repairing cicatrix，It is characterized in that: be made up by weight percentage of following component: water 50-65%、Glycerol 5-8%、Xanthan gum 3-4%、Butanediol 4-6%、Carbomer 2-3%、Hyaluronate sodium 0.2-0.5%、Sodium hydroxide 0.3-1.2%、Allantoin 0.5-0.9%、Nicotiamide 0.3-0.5%、Glucose glycosaminoglycan 1-3%、Sensiva SC50 2-4%、Piper methysticum extract 1.5-1.8%、Bulbus Allii Cepae extract 3-6%、Amaranthus caudatus seed extract 0.1-0.6%、Hydrolecithin 1.5-1.6%、Sorbitol 1.2-1.6%、1,2-hexanediol 1.6-2.3%、Tocopherol acetas 2-5%、Soluble collagen 3-4%、Herba portulacae extract 3.5-6.5%、Aloe Barbadensis Miller juice 5-10%.
- A kind of external preparation repairing cicatrix the most according to claim 1, it is characterised in that: described piper methysticum extract is a kind of piper methysticum leaf/root/stem extract.
- A kind of external preparation repairing cicatrix the most according to claim 1, it is characterised in that: described Bulbus Allii Cepae extract is a kind of onion bulb stem extract.
- A kind of external preparation repairing cicatrix the most according to claim 1, it is characterized in that: be made up by weight percentage of following component: water 55%, glycerol 5%, xanthan gum 3%, butanediol 4%, carbomer 2%, hyaluronate sodium 0.2%, sodium hydroxide 0.3%, allantoin 0.5%, nicotiamide 0.3%, glucose glycosaminoglycan 1.7%, Sensiva SC50 2%, piper methysticum extract 1.5%, Bulbus Allii Cepae extract 3%, amaranthus caudatus seed extract 0.5%, hydrolecithin 1.5%, sorbitol 1.4%, 1, 2-hexanediol 1.6%, tocopherol acetas 2%, soluble collagen 3.5%, Herba portulacae extract 3.5%, Aloe Barbadensis Miller juice 7.5%.
- 5. the preparation method of the external preparation repairing cicatrix, it is characterized in that: take glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide, by glycerol, xanthan gum, butanediol, carbomer, hyaluronate sodium, sodium hydroxide, allantoin and nicotiamide deionized water, piper methysticum extract, Bulbus Allii Cepae extract, amaranthus caudatus seed extract, hydrolecithin, sorbitol, 1, 2-hexanediol, tocopherol acetas, soluble collagen, 75～85 DEG C it are warming up to after Herba portulacae extract stirring and evenly mixing, take out after insulation 10～15min, stirring cools to about 40 DEG C, sequentially add Aloe Barbadensis Miller juice and water, i.e. complete after stirring and dissolving is complete.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610526860.8A CN105998573A (en) | 2016-07-07 | 2016-07-07 | Externally applied medicament for repairing scars and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610526860.8A CN105998573A (en) | 2016-07-07 | 2016-07-07 | Externally applied medicament for repairing scars and preparation method thereof |
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| CN105998573A true CN105998573A (en) | 2016-10-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610526860.8A Pending CN105998573A (en) | 2016-07-07 | 2016-07-07 | Externally applied medicament for repairing scars and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727115A (en) * | 2016-12-13 | 2017-05-31 | 广东科玮生物技术股份有限公司 | A kind of face cream repaired for hyperplastic scar and preparation method thereof |
| CN107028830A (en) * | 2017-04-25 | 2017-08-11 | 徐子雁 | It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia |
| CN107714562A (en) * | 2017-11-29 | 2018-02-23 | 诺斯贝尔化妆品股份有限公司 | A kind of night maintenance elite breast |
| CN108904408A (en) * | 2018-08-16 | 2018-11-30 | 余荣华 | A kind of formula of anti-wrinkle product |
| CN109381409A (en) * | 2018-11-30 | 2019-02-26 | 广州润虹医药科技股份有限公司 | A kind of Aloe Vera Gel and preparation method thereof |
| JP6973740B1 (en) * | 2021-03-26 | 2021-12-01 | 聖子 藤川 | Skin beauty composition and skin beauty method |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727115A (en) * | 2016-12-13 | 2017-05-31 | 广东科玮生物技术股份有限公司 | A kind of face cream repaired for hyperplastic scar and preparation method thereof |
| CN107028830A (en) * | 2017-04-25 | 2017-08-11 | 徐子雁 | It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia |
| CN107028830B (en) * | 2017-04-25 | 2021-03-09 | 徐子雁 | Medicine for preventing scar hyperplasia and preparation process thereof |
| CN107714562A (en) * | 2017-11-29 | 2018-02-23 | 诺斯贝尔化妆品股份有限公司 | A kind of night maintenance elite breast |
| CN108904408A (en) * | 2018-08-16 | 2018-11-30 | 余荣华 | A kind of formula of anti-wrinkle product |
| CN109381409A (en) * | 2018-11-30 | 2019-02-26 | 广州润虹医药科技股份有限公司 | A kind of Aloe Vera Gel and preparation method thereof |
| JP6973740B1 (en) * | 2021-03-26 | 2021-12-01 | 聖子 藤川 | Skin beauty composition and skin beauty method |
| JP2022150429A (en) * | 2021-03-26 | 2022-10-07 | 聖子 藤川 | Skin beauty composition and skin beautifying method |
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Application publication date: 20161012 |