CN105998390A - Pharmaceutical composition for treatment of seborrheic dermatitis and preparation method thereof - Google Patents
Pharmaceutical composition for treatment of seborrheic dermatitis and preparation method thereof Download PDFInfo
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- CN105998390A CN105998390A CN201510837959.5A CN201510837959A CN105998390A CN 105998390 A CN105998390 A CN 105998390A CN 201510837959 A CN201510837959 A CN 201510837959A CN 105998390 A CN105998390 A CN 105998390A
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Abstract
The invention relates to the medicine field, in particular to a pharmaceutical composition for treatment of seborrheic dermatitis and a preparation method thereof. The pharmaceutical composition comprises the following components by mass: 10-12 parts of grimmia pilifera; 6-8 parts of sea buckthorn oil; 12-20 parts of dried tangerine peel; 10-14 parts of lantana camara; 12-16 parts of mint leaf; and 12-16 parts of Zanthoxylum nitidum leaf. The invention selects a grimmia pilifera extract as the main component for treatment of seborrheic dermatitis, the inventor finds the significant efficacy of grimmia pilifera on seborrheic dermatitis, and by cooperation with lantana camara, mint leaf, Zanthoxylum nitidum leaf and dried tangerine peel, the treatment effect can be more significant, and the use of sea buckthorn oil can make the skin reach better absorption effect and speed up the treatment effect.
Description
Technical field
The present invention relates to field of medicaments, be specifically related to a kind of pharmaceutical composition treating seborrheic dermatitis and preparation method thereof.
Background technology
Seborrheic dermatitis refers to smegma hyperfunctioning.Show as scalp greasiness, greasy shinny, desquamation is more, it is easier at sebum prosperity position occur, it is to occur at a kind of chronic inflammatory disease on the basis of seborrhea, infringement is scarlet or yellowish red color patch, surface has greasy scales or crust, it is often accompanied by pruritus in various degree so that patient suffering can't bear, and affects daily life.
Summary of the invention
The technical problem to be solved is to provide a kind of pharmaceutical composition treating seborrheic dermatitis and preparation method thereof.
The technical problem to be solved is achieved by the following technical programs:
A kind of pharmaceutical composition treating seborrheic dermatitis, including the component of following mass fraction: semi-finished herba abri 10-12 part；Oleum Hippophae 6-8 part；Pericarpium Citri Reticulatae 12-20 part；Lantana 10-14 part；Mentha leave 12-16 part；Shinyleaf pricklyash leaf 12-16 part.
Preferably, described pharmaceutical composition includes the component of following mass fraction: semi-finished herba abri 11 parts；Oleum Hippophae 7 parts；Pericarpium Citri Reticulatae 16 parts；Lantana 12 parts；Mentha leave 14 parts；Shinyleaf pricklyash leaf 14 parts.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis, it is characterised in that first described semi-finished herba abri, lantana, mentha leave, shinyleaf pricklyash leaf are cleaned, puts into extruding juice in extruder, crosses 100 mesh sieves, collect filtrate standby.
Further, the collection medicine juice that water mixing decoction to the water residue 1/10th of Pericarpium Citri Reticulatae and ten times of quality removed slag cools standby.
Further, mix with Oleum Hippophae after standby filtrate and medicine juice are mixed also, be pharmaceutical composition of the present invention.
There is advantages that
The present invention selects semi-finished herba abri extract as the Main Components for the treatment of seborrheic dermatitis, inventor finds evident in efficacy for seborrheic dermatitis of semi-finished herba abri, coordinate lantana, mentha leave, shinyleaf pricklyash leaf and Pericarpium Citri Reticulatae again, make therapeutic effect more notable, and using Oleum Hippophae, it is possible to the assimilation effect making skin is more preferable, accelerates therapeutic effect, skin water loss can also be pinned, reduce dry itching.
Detailed description of the invention
The present invention will be described in detail for embodiment in detail below.
Embodiment 1
A kind of pharmaceutical composition treating seborrheic dermatitis, including the component of following mass fraction: semi-finished herba abri 10-12 part；Oleum Hippophae 6-8 part；Pericarpium Citri Reticulatae 12-20 part；Lantana 10-14 part；Mentha leave 12-16 part；Shinyleaf pricklyash leaf 12-16 part.
Preferably, described pharmaceutical composition includes the component of following mass fraction: semi-finished herba abri 11 parts；Oleum Hippophae 7 parts；Pericarpium Citri Reticulatae 16 parts；Lantana 12 parts；Mentha leave 14 parts；Shinyleaf pricklyash leaf 14 parts.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis, it is characterised in that first described semi-finished herba abri, lantana, mentha leave, shinyleaf pricklyash leaf are cleaned, puts into extruding juice in extruder, crosses 100 mesh sieves, collect filtrate standby；The collection medicine juice that water mixing decoction to the water residue 1/10th of Pericarpium Citri Reticulatae and ten times of quality removed slag again cools standby；Then mix with Oleum Hippophae after standby filtrate and medicine juice being mixed also, be pharmaceutical composition of the present invention.
Embodiment 2
A kind of pharmaceutical composition treating seborrheic dermatitis, including the component of following mass fraction: semi-finished herba abri 12 parts；Oleum Hippophae 6 parts；Pericarpium Citri Reticulatae 18 parts；Lantana 11 parts；Mentha leave 15 parts；Shinyleaf pricklyash leaf 13 parts.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis, it is characterised in that first described semi-finished herba abri, lantana, mentha leave, shinyleaf pricklyash leaf are cleaned, puts into extruding juice in extruder, crosses 100 mesh sieves, collect filtrate standby；The collection medicine juice that water mixing decoction to the water residue 1/10th of Pericarpium Citri Reticulatae and ten times of quality removed slag again cools standby；Then mix with Oleum Hippophae after standby filtrate and medicine juice being mixed also, be pharmaceutical composition of the present invention.
Comparative example
A kind of pharmaceutical composition treating seborrheic dermatitis, including the component of following mass fraction: Oleum Hippophae 7 parts；Pericarpium Citri Reticulatae 16 parts；Lantana 12 parts；Shinyleaf pricklyash leaf 14 parts.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis, it is characterised in that first described lantana, shinyleaf pricklyash leaf are cleaned, puts into extruding juice in extruder, crosses 100 mesh sieves, collect filtrate standby；The collection medicine juice that water mixing decoction to the water residue 1/10th of Pericarpium Citri Reticulatae and ten times of quality removed slag again cools standby；Then mix with Oleum Hippophae after standby filtrate and medicine juice being mixed also, be pharmaceutical composition of the present invention.
Test example 1
Zhao so-and-so, man, 26 years old, clinical realization: skin is oily skin, and skin has the surface symptoms such as pruritus, desquamation, and erythema is more apparent, be diagnosed as seborrheic dermatitis, prepare pharmaceutical composition according to embodiment 1, every day potion, every day twice, sooner or later taking, 7 days courses for the treatment of, after taking three weeks continuously, skin disappears completely without greasy and gargalesthesia, skin surface symptom.
Test example 2
Ma, female, 35 years old, clinical manifestation: occur well-defined luteotestaceous erythema on skin, with the fresh bits of exquisiteness and incrustation, and with pruritis, pharmaceutical composition is prepared according to embodiment 2, every day, potion, every day twice, took sooner or later, 7 days courses for the treatment of, after taking three weeks continuously, skin is clearly better without gargalesthesia, skin lesion.
Experimental example
Carrying out treating seborrheic dermatitis by pharmaceutical composition prepared in above-described embodiment 1, embodiment 2 and comparative example, its traditional Chinese medical science diagnostic criteria is: the erythema of yellow occurs in skin lesion, with the fresh bits of exquisiteness and incrustation, and with pruritis.The patient selecting 90 examples to have above-mentioned symptom has carried out clinical observation on the therapeutic effect, wherein male 33 example, women 27 example, and age characteristics is 19-52 year, is randomly divided into 3 groups.
As follows with reference to disease of tcm Standardization of diagnosis and curative effect:
Effective: skin surface symptom disappears completely, skin is without greasy and gargalesthesia.
Effective: skin surface symptom is more than or equal to 50%, greasy significantly reduces, and gargalesthesia substantially alleviates.
Invalid: skin surface symptom is more than or equal to 30%, but less than 50%, greasy and scratchiness slightly alleviates or unchanged.Add up to the above two and have total effective rate.Result see table.
Efficacy result statistics before and after table 1 treatment
As can be seen from the above table, medicine composite for curing seborrheic dermatitis effect provided by the present invention is notable, has no side effect, and total effective rate reaches more than 97%, especially evident in efficacy with Chinese medicine composition described in embodiment 2.
Embodiment described above only have expressed embodiments of the present invention; it describes more concrete and detailed; but therefore can not be interpreted as the restriction to the scope of the claims of the present invention; in every case the technical scheme using the form of equivalent or equivalent transformation to be obtained, all should fall within the scope and spirit of the invention.
Claims (5)
1. the pharmaceutical composition treating seborrheic dermatitis, it is characterised in that include the component of following mass fraction: semi-finished herba abri 10-12 part；Oleum Hippophae 6-8 part；Pericarpium Citri Reticulatae 12-20 part；Lantana 10-14 part；Mentha leave 12-16 part；Shinyleaf pricklyash leaf 12-16 part.
A kind of pharmaceutical composition treating seborrheic dermatitis the most according to claim 1, it is characterised in that include the component of following mass fraction: semi-finished herba abri 11 parts；Oleum Hippophae 7 parts；Pericarpium Citri Reticulatae 16 parts；Lantana 12 parts；Mentha leave 14 parts；Shinyleaf pricklyash leaf 14 parts.
A kind of preparation method of the pharmaceutical composition treating seborrheic dermatitis, it is characterized in that first described semi-finished herba abri, lantana, mentha leave, shinyleaf pricklyash leaf being cleaned, put into extruding juice in extruder, cross 100 mesh sieves, collect filtrate standby.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis the most according to claim 3, it is characterised in that the collection medicine juice that water mixing decoction to the water residue 1/10th of Pericarpium Citri Reticulatae and ten times of quality removed slag cools standby.
The preparation method of a kind of pharmaceutical composition treating seborrheic dermatitis the most according to claim 4, it is characterised in that mix with Oleum Hippophae after standby filtrate and medicine juice are mixed also, be pharmaceutical composition of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510837959.5A CN105998390A (en) | 2015-11-26 | 2015-11-26 | Pharmaceutical composition for treatment of seborrheic dermatitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510837959.5A CN105998390A (en) | 2015-11-26 | 2015-11-26 | Pharmaceutical composition for treatment of seborrheic dermatitis and preparation method thereof |
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| Publication Number | Publication Date |
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| CN105998390A true CN105998390A (en) | 2016-10-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510837959.5A Pending CN105998390A (en) | 2015-11-26 | 2015-11-26 | Pharmaceutical composition for treatment of seborrheic dermatitis and preparation method thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1622817A (en) * | 2002-04-15 | 2005-06-01 | 山东哲夫 | Drinking tea for treating dermatitis |
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2015
- 2015-11-26 CN CN201510837959.5A patent/CN105998390A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1622817A (en) * | 2002-04-15 | 2005-06-01 | 山东哲夫 | Drinking tea for treating dermatitis |
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Application publication date: 20161012 |
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| RJ01 | Rejection of invention patent application after publication |